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https://www.readbyqxmd.com/read/28079633/criterion-referenced-values-of-grip-strength-and-usual-gait-speed-using-instrumental-activities-of-daily-living-disability-as-the-criterion
#1
Meng-Chih Lee, Chih-Cheng Hsu, Yi-Fen Tsai, Ching-Yu Chen, Cheng-Chieh Lin, Ching-Yi Wang
BACKGROUND AND PURPOSE: Current evidence suggests that grip strength and usual gait speed (UGS) are important predictors of instrumental activities of daily living (IADL) disability. Knowing the optimum cut points of these tests for discriminating people with and without IADL disability could help clinicians or researchers to better interpret the test results and make medical decisions. The purpose of this study was to determine the cutoff values of grip strength and UGS for best discriminating community-dwelling older adults with and without IADL disability, separately for men and women, and to investigate their association with IADL disability...
January 10, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28078802/evaluation-of-pva-biodegradable-electric-conductive-membranes-for-nerve-regeneration-in-axonotmesis-injuries-the-rat-sciatic-nerve-animal-model
#2
J Ribeiro, A R Caseiro, T Pereira, Pas Armada-da-Silva, I Pires, J Prada, I Amorim, I Leal Reis, S Amado, J D Santos, S Bompasso, S Raimondo, Asp Varejão, S Geuna, A L Luís, A C Maurício
The therapeutic effect of three polyvinyl alcohol (PVA) membranes loaded with electrically conductive materials - carbon nanotubes (PVA-CNTs) and polypyrrole (PVA-PPy) - were tested in vivo for neuro-muscular regeneration after an axonotmesis injury in the rat sciatic nerve. The membranes electrical conductivity measured was 1.5±0.5x10(-6) S/m, 579±0.6x10(-6) S/m, and 1837.5±0.7 x10(-6) S/m, respectively. At week-12, a residual motor and nociceptive deficit were present in all treated groups, but at week-12, a better recovery to normal gait pattern of the PVA-CNTs and PVA-PPy treated groups was observed...
January 12, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28077804/the-complex-genetics-of-gait-speed-genome-wide-meta-analysis-approach
#3
Dan Ben-Avraham, David Karasik, Joe Verghese, Kathryn L Lunetta, Jennifer A Smith, John A Eicher, Rotem Vered, Joris Deelen, Alice M Arnold, Aron S Buchman, Toshiko Tanaka, Jessica D Faul, Maria Nethander, Myriam Fornage, Hieab H Adams, Amy M Matteini, Michele L Callisaya, Albert V Smith, Lei Yu, Philip L De Jager, Denis A Evans, Vilmundur Gudnason, Albert Hofman, Alison Pattie, Janie Corley, Lenore J Launer, Davis S Knopman, Neeta Parimi, Stephen T Turner, Stefania Bandinelli, Marian Beekman, Danielle Gutman, Lital Sharvit, Simon P Mooijaart, David C Liewald, Jeanine J Houwing-Duistermaat, Claes Ohlsson, Matthijs Moed, Vincent J Verlinden, Dan Mellström, Jos N van der Geest, Magnus Karlsson, Dena Hernandez, Rebekah McWhirter, Yongmei Liu, Russell Thomson, Gregory J Tranah, Andre G Uitterlinden, David R Weir, Wei Zhao, John M Starr, Andrew D Johnson, M Arfan Ikram, David A Bennett, Steven R Cummings, Ian J Deary, Tamara B Harris, Sharon L R Kardia, Thomas H Mosley, Velandai K Srikanth, Beverly G Windham, Ann B Newman, Jeremy D Walston, Gail Davies, Daniel S Evans, Eline P Slagboom, Luigi Ferrucci, Douglas P Kiel, Joanne M Murabito, Gil Atzmon
Emerging evidence suggests that the basis for variation in late-life mobility is attributable, in part, to genetic factors, which may become increasingly important with age. Our objective was to systematically assess the contribution of genetic variation to gait speed in older individuals. We conducted a meta-analysis of gait speed GWASs in 31,478 older adults from 17 cohorts of the CHARGE consortium, and validated our results in 2,588 older adults from 4 independent studies. We followed our initial discoveries with network and eQTL analysis of candidate signals in tissues...
January 10, 2017: Aging
https://www.readbyqxmd.com/read/28077395/the-effects-of-posterior-cruciate-ligament-deficiency-on-posterolateral-corner-structures-under-gait-and-squat-loading-conditions-a-computational-knee-model
#4
K-T Kang, Y-G Koh, M Jung, J-H Nam, J Son, Y H Lee, S-J Kim, S-H Kim
OBJECTIVES: The aim of the current study was to analyse the effects of posterior cruciate ligament (PCL) deficiency on forces of the posterolateral corner structure and on tibiofemoral (TF) and patellofemoral (PF) contact force under dynamic-loading conditions. METHODS: A subject-specific knee model was validated using a passive flexion experiment, electromyography data, muscle activation, and previous experimental studies. The simulation was performed on the musculoskeletal models with and without PCL deficiency using a novel force-dependent kinematics method under gait- and squat-loading conditions, followed by probabilistic analysis for material uncertain to be considered...
January 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28076431/knee-cartilage-thickness-t1%C3%AF-and-t2-relaxation-time-are-related-to-articular-cartilage-loading-in-healthy-adults
#5
Sam Van Rossom, Colin Robert Smith, Lianne Zevenbergen, Darryl Gerard Thelen, Benedicte Vanwanseele, Dieter Van Assche, Ilse Jonkers
Cartilage is responsive to the loading imposed during cyclic routine activities. However, the local relation between cartilage in terms of thickness distribution and biochemical composition and the local contact pressure during walking has not been established. The objective of this study was to evaluate the relation between cartilage thickness, proteoglycan and collagen concentration in the knee joint and knee loading in terms of contact forces and pressure during walking. 3D gait analysis and MRI (3D-FSE, T1ρ relaxation time and T2 relaxation time sequence) of fifteen healthy subjects were acquired...
2017: PloS One
https://www.readbyqxmd.com/read/28075436/gait-kinematic-deviations-in-patients-with-developmental-dysplasia-of-the-hip-treated-with-total-hip-arthroplasty
#6
Yong Nie, Ning Ning, Fuxing Pei, Bin Shen, Zongke Zhou, Zongming Li
Comprehensive gait analysis of patients with Crowe type II and III developmental dysplasia of the hip (DDH) after successful total hip arthroplasty (THA) is lacking in the literature. This study evaluated gait function in joint kinematics after unilateral and bilateral THA in patients with DDH. In addition, the effect of high cup position on gait function was investigated. A total of 16 unilateral and 15 bilateral cementless THA patients due to DDH and 10 healthy participants comprised the study population...
January 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/28074998/-prognostic-factors-of-functional-recovery-from-a-stroke-at-one-year
#7
J A Moreno-Palacios, I Moreno-Martinez, A Bartolome-Nogues, E Lopez-Blanco, R Juarez-Fernandez, I Garcia-Delgado
INTRODUCTION: Recovery of the ability to walk and independence is fundamental for any patient who suffers a stroke, and it can be influenced by a number of factors. AIM: To determine what variables are more important to achieve a good functional recovery at one year after the stroke. PATIENTS AND METHODS: An observational, longitudinal prospective study was conducted with 231 patients diagnosed with a stroke in the year 2013. An analysis was performed of the clinical characteristics, socio-demographic data, neurological situation at the time of hospitalisation -National Institute of Health Stroke Scale (NIHSS)-, functional situation (Rankin Scale and Barthel Index) and ability to walk, both on hospitalisation and on discharge from rehabilitation and at one year...
January 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28074440/distal-femoral-extension-and-shortening-osteotomy-as-a-part-of-multilevel-surgery-in-children-with-cerebral-palsy
#8
Matthias C M Klotz, Klemens Hirsch, Daniel Heitzmann, Michael W Maier, Sebastien Hagmann, Thomas Dreher
BACKGROUND: There are several reports describing an increase in anterior pelvic tilt after hamstring lengthening in children with cerebral palsy (CP). Distal femoral extension and shortening osteotomy (DFESO) is an alternative treatment for correction of fl exed knee gait, but investigations analyzing outcome and infl uence on adjacent joint are few in the literature. The purpose of this study was to analyze the influence of DFESO on knee and pelvis in children with CP. Furthermore, it was of interest if an additional patellar tendon advancement (PA) infl uences outcome...
December 23, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28068857/abobotulinumtoxina-dysport-%C3%A2-improves-function-according-to-goal-attainment-in-children-with-dynamic-equinus-due-to-cerebral-palsy
#9
Ann Tilton, Barry Russman, Resa Aydin, Umit Dincer, Raul G Escobar, Sehim Kutlay, Zbigniew Lipczyk, Juan Carlos Velez, Anne-Sophie Grandoulier, Anissa Tse, Philippe Picaut, Mauricio R Delgado
This secondary analysis of a large (n = 241), randomized, double-blind study evaluated the efficacy of 2 doses of abobotulinumtoxinA + standard of care (SOC) versus placebo + SOC in enabling children with dynamic equinus due to cerebral palsy to achieve their functional goals using Goal Attainment Scaling. Most parents/caregivers selected goals targeting aspects of gait improvement as most relevant. Mean (95% confidence interval) Goal Attainment Scaling T scores at week 4 were higher for both abobotulinumtoxinA groups versus placebo (treatment difference vs placebo: 10 U/kg/leg: 5...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28068837/immediate-effects-of-acupuncture-treatment-on-intra-and-inter-limb-contributions-to-body-support-during-gait-in-patients-with-bilateral-medial-knee-osteoarthritis
#10
Yen-Hung Liu, I-Pin Wei, Ting-Ming Wang, Tung-Wu Lu, Jaung-Geng Lin
Knee osteoarthritis (OA) often leads to altered balance control, joint motion and loading patterns during gait. Acupuncture has been proven to be effective in pain relief but its effects on inter-joint load-sharing for body balance have not been reported. The current study bridged the gap by quantifying the immediate effects of acupuncture on the inter-joint and inter-limb load-sharing in patients with knee OA during level walking in terms of the total support moment (Ms) and the contribution of individual joints to the total support moment...
January 9, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28068520/impact-loading-following-quadriceps-strength-training-in-individuals-with-medial-knee-osteoarthritis-and-varus-alignment
#11
Crystal O Kean, Rana S Hinman, Tim V Wrigley, Boon-Whatt Lim, Kim L Bennell
BACKGROUND: Greater impact loading at initial contact is postulated to play a role in the progression of osteoarthritis. Quadriceps weakness is common in individuals with knee osteoarthritis and may contribute to high impact loading. The purpose of this study was to examine the effects of quadriceps strengthening on impact loading parameters. METHODS: Data from 97 individuals with knee osteoarthritis who participated in a randomized clinical trial examining effects of a 12-week quadriceps strengthening program was used to conduct this secondary exploratory analysis...
January 4, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28067123/the-effect-of-a-supervised-community-based-exercise-program-on-balance-balance-confidence-and-gait-in-individuals-with-lower-limb-amputation
#12
Carol A Miller, Jennifer E Williams, Katey L Durham, Selena C Hom, Julie L Smith
BACKGROUND: Many individuals with lower limb loss report concern with walking ability after completing structured traditional rehabilitation. OBJECTIVES: The purpose of this study was to explore the impact of a supervised community-based exercise program on balance, balance confidence, and gait in individuals with lower limb amputation. STUDY DESIGN: Repeated measures. METHODS: The supervised exercise program was offered biweekly for 6 weeks...
January 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28066528/psychometric-evaluation-of-the-hill-assessment-index-hai-and-stair-assessment-index-sai-in-high-functioning-transfemoral-amputees
#13
M Jason Highsmith, Jason T Kahle, Brian Kaluf, Rebecca M Miro, Larry J Mengelkoch, Tyler D Klenow
The hill assessment index (HAI) and stair assessment index (SAI) were developed to objectively evaluate ramp and stair gait. This study's purpose was to determine the validity and reliability of these tests in a sample of persons with unilateral transfemoral amputation (TFA) using microprocessor prosthetic knee systems. All subjects were fit with a microprocessor knee system. After accommodation, subjects performed three trials ascending and descending a 5° ramp and a flight of stairs while being recorded on video...
September 2016: Technology and Innovation
https://www.readbyqxmd.com/read/28066523/effects-of-the-genium-microprocessor-knee-system-on-knee-moment-symmetry-during-hill-walking
#14
M Jason Highsmith, Tyler D Klenow, Jason T Kahle, Matthew M Wernke, Stephanie L Carey, Rebecca M Miro, Derek J Lura
Use of the Genium microprocessor knee (MPK) system reportedly improves knee kinematics during walking and other functional tasks compared to other MPK systems. This improved kinematic pattern was observed when walking on different hill conditions and at different speeds. Given the improved kinematics associated with hill walking while using the Genium, a similar improvement in the symmetry of knee kinetics is also feasible. The purpose of this study was to determine if Genium MPK use would reduce the degree of asymmetry (DoA) of peak stance knee flexion moment compared to the C-Leg MPK in transfemoral amputation (TFA) patients...
September 2016: Technology and Innovation
https://www.readbyqxmd.com/read/28064358/incipient-progressive-supranuclear-palsy-is-more-common-than-expected-and-may-comprise-clinicopathological-subtypes-a-forensic-autopsy-series
#15
Koji Yoshida, Yukiko Hata, Koshi Kinoshita, Shutaro Takashima, Kortaro Tanaka, Naoki Nishida
We investigated 998 serial Japanese forensic autopsy cases (0-101 years old, mean age 61.7 ± 21.9), with no case selection, using immunohistochemistry to detect cases with progressive supranuclear palsy (PSP). Twenty-nine cases (mean age 82.3 ± 7.2 years, 11 males, 18 females) fulfilled the National Institute of Neuronal Disorders and Stroke (NINDS)-PSP pathological criteria (2.9% of all cases, 4.6% of cases over 60). All had neuronal and glial inclusions in the basal ganglia and brainstem. However, 13 cases had low tau pathology and were categorized as atypical PSP...
January 7, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28064084/comparison-of-tri-axial-accelerometers-step-count-accuracy-in-slow-walking-conditions
#16
Yuanyuan Feng, Christopher K Wong, Vandana Janeja, Ravi Kuber, Helena M Mentis
Accelerometers have shown great promise and popularity for monitoring gait. However, the accuracy of accelerometers for gait analysis in slow walking conditions is largely unknown. In this study, we compared the accuracy of three accelerometers recommended for gait analysis - Axivity AX3, APDM Opal, and the Actigraph wGT3X-BT, by holding the step-count algorithm constant. We evaluated device accuracy in four minutes of treadmill walking at the speeds of 0.9m/s, 1.1m/s, and 1.3m/s. We constructed a symbolization of the gait data to count the steps using Piecewise Aggregate Approximation and compared the estimated step counts with observer counted steps from video recordings...
December 15, 2016: Gait & Posture
https://www.readbyqxmd.com/read/28064033/altered-gait-mechanics-and-elevated-serum-pro-inflammatory-cytokines-in-asymptomatic-patients-with-mri-evidence-of-knee-cartilage-loss
#17
Shannon N Edd, Julien Favre, Katerina Blazek, Patrick Omoumi, Jessica L Asay, Thomas P Andriacchi
OBJECTIVE: To test if sagittal plane gait mechanics parameters and serum inflammation levels differ between healthy asymptomatic subjects and asymptomatic subjects with magnetic resonance imaging (MRI) evidence of cartilage loss. DESIGN: Gait mechanics and resting serum tumor necrosis factor-α (TNFα) concentrations were measured for two groups of asymptomatic subjects recruited for a previous study: Pre-Osteoarthritis (OA) subjects had MRI evidence of partial- or full-thickness knee cartilage loss in at least one compartment (n=52 (30 female), 1...
January 4, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28063896/clinical-correlation-of-abnormal-findings-on-magnetic-resonance-elastography-in-idiopathic-normal-pressure-hydrocephalus
#18
Avital Perry, Christopher S Graffeo, Nikoo Fattahi, Mona M ElSheikh, Nealey Cray, Arvin Arani, Richard L Ehman, Kevin J Glaser, Armando Manduca, Fredric B Meyer, John Huston
BACKGROUND: Idiopathic normal pressure hydrocephalus (iNPH) is ventriculomegaly syndrome characterized by dementia, urinary incontinence, and gait disturbance, which is potentially reversible following ventriculoperitoneal shunting (VPS). Magnetic resonance elastography (MRE) is an evolving imaging technology that noninvasively measures tissue viscoelasticity. OBJECTIVE: We studied iNPH patients using MRE prior to shunting, compared them to normal controls, and analyzed associations between MRE findings and clinical features, as a pilot assessment of MRE in iNPH...
January 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28063273/mechanisms-of-compensation-in-the-gait-of-patients-with-drop-foot
#19
Błażkiewicz Michalina, Wiszomirska Ida, Kaczmarczyk Katarzyna, Grażyna Brzuszkiewicz-Kuźmicka, Wit Andrzej
BACKGROUND: Drop foot is a complex syndrome, with multiple interactions between joints and muscles. Abnormalities in movement patterns can be measured using motion capture techniques, but identifying compensation mechanisms remains challenging. METHODS: In order to identify compensatory mechanisms in patients with drop foot, this study evaluated a sample of 15 such patients using a computerized gait analysis system, as compared to a group of 15 healthy subjects...
January 3, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28057517/myoelectric-activation-pattern-changes-in-the-involved-limb-of-individuals-with-transtibial-amputation-during-locomotor-state-transitions
#20
Bryson H Nakamura, Michael E Hahn
OBJECTIVE: To investigate whether lower extremity muscle activation patterns differ in the strides leading to locomotive state transitions in the involved limb of individuals with transtibial amputation. It was hypothesized that all transitions would elicit activation differences between strides as the subjects moved toward the transition event. DESIGN: A single sample, observational study. SETTING: The study was conducted in the hallways, ramps and stairs of a university building...
January 2, 2017: Archives of Physical Medicine and Rehabilitation
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