keyword
https://read.qxmd.com/read/38607430/a-survey-based-approach-on-restless-legs-syndrome-practices-and-perspectives-among-italian-neurologists
#21
JOURNAL ARTICLE
Elena Antelmi, Gloria Pompea Mingolla, Maria Paola Mogavero, Raffaele Ferri, Giuseppe Lanza, Francesca Morgante, Chiara Bonetto, Antonella Conte, Luigi Ferini-Strambi, Giuseppe Plazzi, Alfredo Berardelli, Michele Tinazzi
INTRODUCTION: Restless Legs Syndrome (RLS) is a widely prevalent and complex neurological disorder. Despite notable advancements in managing RLS, the disorder continues to face challenges related to its recognition and management. OBJECTIVE: This study seeks to gain comprehensive insights into the knowledge and clinical practices among Italian neurologists regarding RLS diagnosis, management, and treatment, comparing approaches among general neurologists, movement disorder specialists, and sleep experts...
April 12, 2024: Journal of Neurology
https://read.qxmd.com/read/38606984/molecular-imprinting-based-sers-detection-strategy-for-the-large-size-protein-quantitation-and-curbing-non-specific-recognition
#22
JOURNAL ARTICLE
Xuan Chen, Abbas Ostovan, Maryam Arabi, Yunqing Wang, Lingxin Chen, Jinhua Li
Molecular imprinting-based surface-enhanced Raman scattering (MI-SERS) sensors have shown remarkable potential from an academic standpoint. However, their practical applications, especially in the detection of large-size protein (≥10 nm), face challenges due to the lack of versatile sensing strategies and nonspecific fouling of matrix species. Herein, we propose a Raman reporter inspector mechanism (RRIM) implemented on a protein-imprinted polydopamine (PDA) layer coated on the SERS active substrate...
April 12, 2024: Analytical Chemistry
https://read.qxmd.com/read/38606066/improving-the-maize-crop-row-navigation-line-recognition-method-of-yolox
#23
JOURNAL ARTICLE
Hailiang Gong, Weidong Zhuang, Xi Wang
The accurate identification of maize crop row navigation lines is crucial for the navigation of intelligent weeding machinery, yet it faces significant challenges due to lighting variations and complex environments. This study proposes an optimized version of the YOLOX-Tiny single-stage detection network model for accurately identifying maize crop row navigation lines. It incorporates adaptive illumination adjustment and multi-scale prediction to enhance dense target detection. Visual attention mechanisms, including Efficient Channel Attention and Cooperative Attention modules, are introduced to better extract maize features...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38603924/the-role-of-perceptual-processing-in-the-oddball-effect-revealed-by-the-thatcher-illusion
#24
JOURNAL ARTICLE
Akira Sarodo, Kentaro Yamamoto, Katsumi Watanabe
When a novel stimulus (oddball) appears after repeated presentation of an identical stimulus, the oddball is perceived to last longer than the repeated stimuli, a phenomenon known as the oddball effect. We investigated whether the perceptual or physical differences between the repeated and oddball stimuli are more important for the oddball effect. To manipulate the perceptual difference while keeping their physical visual features constant, we used the Thatcher illusion, in which an inversion of a face hinders recognition of distortion in its facial features...
April 10, 2024: Vision Research
https://read.qxmd.com/read/38603885/recent-advances-in-functional-nucleic-acid-decorated-nanomaterials-for-cancer-imaging-and-therapy
#25
REVIEW
Liu Wu, Ruitao Yuan, Tong Wen, Yingfeng Qin, Yumin Wang, Xiaoling Luo, Jin-Wen Liu
Nanomaterials possess unusual physicochemical properties including unique optical, magnetic, electronic properties, and large surface-to-volume ratio. However, nanomaterials face some challenges when they were applied in the field of biomedicine. For example, some nanomaterials suffer from the limitations such as poor selectivity and biocompatibility, low stability, and solubility. To address the above-mentioned obstacles, functional nucleic acid has been widely served as a powerful and versatile ligand for modifying nanomaterials because of their unique characteristics, such as ease of modification, excellent biocompatibility, high stability, predictable intermolecular interaction and recognition ability...
April 10, 2024: Biomedicine & Pharmacotherapy
https://read.qxmd.com/read/38601923/multimodal-automatic-assessment-of-acute-pain-through-facial-videos-and-heart-rate-signals-utilizing-transformer-based-architectures
#26
JOURNAL ARTICLE
Stefanos Gkikas, Nikolaos S Tachos, Stelios Andreadis, Vasileios C Pezoulas, Dimitrios Zaridis, George Gkois, Anastasia Matonaki, Thanos G Stavropoulos, Dimitrios I Fotiadis
Accurate and objective pain evaluation is crucial in developing effective pain management protocols, aiming to alleviate distress and prevent patients from experiencing decreased functionality. A multimodal automatic assessment framework for acute pain utilizing video and heart rate signals is introduced in this study. The proposed framework comprises four pivotal modules: the Spatial Module , responsible for extracting embeddings from videos; the Heart Rate Encoder , tasked with mapping heart rate signals into a higher dimensional space; the AugmNet , designed to create learning-based augmentations in the latent space; and the Temporal Module , which utilizes the extracted video and heart rate embeddings for the final assessment...
2024: Front Pain Res (Lausanne)
https://read.qxmd.com/read/38600510/constitutive-knockout-of-interleukin-6-ameliorates-memory-deficits-and-entorhinal-astrocytosis-in-the-mrl-lpr-mouse-model-of-neuropsychiatric-lupus
#27
JOURNAL ARTICLE
Joshua Reynolds, Michelle Huang, Yaxi Li, Myriam Meineck, Tamara Moeckel, Julia Weinmann-Menke, Chandra Mohan, Andreas Schwarting, Chaim Putterman
BACKGROUND: Neuropsychiatric lupus (NPSLE) describes the cognitive, memory, and affective emotional burdens faced by many lupus patients. While NPSLE's pathogenesis has not been fully elucidated, clinical imaging studies and cerebrospinal fluid (CSF) findings, namely elevated interleukin-6 (IL-6) levels, point to ongoing neuroinflammation in affected patients. Not only linked to systemic autoimmunity, IL-6 can also activate neurotoxic glial cells the brain. A prior pre-clinical study demonstrated that IL-6 can acutely induce a loss of sucrose preference; the present study sought to assess the necessity of chronic IL-6 exposure in the NPSLE-like disease of MRL/lpr lupus mice...
April 10, 2024: Journal of Neuroinflammation
https://read.qxmd.com/read/38597943/clinical-and-neuroanatomical-characterization-of-the-semantic-behavioral-variant-of-frontotemporal-dementia-in-a-multicenter-italian-cohort
#28
JOURNAL ARTICLE
Alma Ghirelli, Edoardo Gioele Spinelli, Elisa Canu, Silvia Basaia, Veronica Castelnovo, Giordano Cecchetti, Elisa Sibilla, Teuta Domi, Giuseppe Magnani, Francesca Caso, Paola Caroppo, Sara Prioni, Cristina Villa, Giacomina Rossi, Lucio Tremolizzo, Ildebrando Appollonio, Federico Verde, Nicola Ticozzi, Vincenzo Silani, Massimo Filippi, Federica Agosta
BACKGROUND: Semantic behavioral variant frontotemporal dementia (sbvFTD) is a neurodegenerative condition presenting with specific behavioral and semantic derangements and predominant atrophy of the right anterior temporal lobe (ATL). The objective was to evaluate clinical, neuropsychological, neuroimaging, and genetic features of an Italian sbvFTD cohort, defined according to recently proposed guidelines, compared to semantic variant primary progressive aphasia (svPPA) and behavioral variant FTD (bvFTD) patients...
April 10, 2024: Journal of Neurology
https://read.qxmd.com/read/38596340/social-cognition-abilities-in-patients-with-primary-and-secondary-chronic-pain
#29
JOURNAL ARTICLE
Alessandra Telesca, Alessandra Vergallito, Monica Consonni, Giulia Mattavelli, Alessia Ferrario, Licia Grazzi, Susanna Usai, Leonor Josefina Romero Lauro
Previous evidence suggested that chronic pain is characterized by cognitive deficits, particularly in the social cognition domain. Recently, a new chronic pain classification has been proposed distinguishing chronic primary pain (CPP), in which pain is the primary cause of patients' disease, and chronic secondary pain (CSP), in which pain is secondary to an underlying illness. The present study aimed at investigating social cognition profiles in the two disorders. We included 38 CPP, 43 CSP patients, and 41 healthy controls (HC)...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38595916/pharmacological-enhancement-of-cholinergic-neurotransmission-alleviates-neuroinflammation-and-improves-functional-outcomes-in-a-triple-transgenic-mouse-model-of-alzheimer-s-disease
#30
JOURNAL ARTICLE
Antonio Munafò, Anna Flavia Cantone, Giulia Di Benedetto, Sebastiano Alfio Torrisi, Chiara Burgaletto, Carlo Maria Bellanca, Gabriella Gaudio, Giuseppe Broggi, Rosario Caltabiano, Gian Marco Leggio, Renato Bernardini, Giuseppina Cantarella
Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disorder affecting the elderly population worldwide. Due to the multifactorial nature of the disease, involving impairment of cholinergic neurotransmission and immune system, previous attempts to find effective treatments have faced challenges. Methods: In such scenario, we attempted to investigate the effects of alpha-glyceryl-phosphoryl-choline (α-GPC), a cholinomimetic molecule, on neuroinflammation and memory outcome in the triple transgenic mouse model of AD (3xTg-AD)...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38595063/implicit-induction-of-expressive-suppression-in-regulation-of-happy-crowd-emotions
#31
JOURNAL ARTICLE
Ping Li, Chuanlin Zhu, Peiyao Geng, Weiqi He, Wenbo Luo
Implicit emotion regulation provides an effective means of controlling emotions triggered by a single face without conscious awareness and effort. Crowd emotion has been proposed to be perceived as more intense than it actually is, but it is still unclear how to regulate it implicitly. In this study, participants viewed sets of faces of varying emotionality (e.g. happy to angry) and estimated the mean emotion of each set after being primed with an expressive suppression goal, a cognitive reappraisal goal, or a neutral goal...
April 10, 2024: Social Neuroscience
https://read.qxmd.com/read/38590879/on-the-search-for-efficient-face-recognition-algorithm-subject-to-multiple-environmental-constraints
#32
JOURNAL ARTICLE
John K Essel, Joseph A Mensah, Eric Ocran, Louis Asiedu
From literature, majority of face recognition modules suffer performance challenges when presented with test images acquired under multiple constrained environments (occlusion and varying expressions). The performance of these models further deteriorates as the degree of degradation of the test images increases (relatively higher occlusion level). Deep learning-based face recognition models have attracted much attention in the research community as they are purported to outperform the classical PCA-based methods...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38590248/specialization-of-amygdala-subregions-in-emotion-processing
#33
JOURNAL ARTICLE
Izelle Labuschagne, Juan F Dominguez, Sally Grace, Simone Mizzi, Julie D Henry, Craig Peters, Christine A Rabinak, Erin Sinclair, Valentina Lorenzetti, Gill Terrett, Peter G Rendell, Mangor Pedersen, Darren R Hocking, Markus Heinrichs
The amygdala is important for human fear processing. However, recent research has failed to reveal specificity, with evidence that the amygdala also responds to other emotions. A more nuanced understanding of the amygdala's role in emotion processing, particularly relating to fear, is needed given the importance of effective emotional functioning for everyday function and mental health. We studied 86 healthy participants (44 females), aged 18-49 (mean 26.12 ± 6.6) years, who underwent multiband functional magnetic resonance imaging...
April 2024: Human Brain Mapping
https://read.qxmd.com/read/38586329/ape-recognition-of-familiar-human-faces-changed-by-time-and-covid-19-face-masks
#34
JOURNAL ARTICLE
Lindsay Murray
Reports of primates being able to recognise familiar humans are rare in the literature and tend to be regarded as anecdotal. The COVID-19 pandemic created two unique conditions facilitating the observation of spontaneous face recognition in zoo apes: i) lengthy gaps in contact with human visitors due to lockdowns and zoo closures, and ii) the wearing of face masks obscuring at least half the face of familiar individuals. Here, I report on the historical context of the familiarity between a primatologist and individual apes of two species, how those apes consistently showed recognition of this particular human over a time span of up to thirty years, how facial recognition was extended to family members, and how recognition persisted even when a significant portion of the face was obscured by a mask...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38586236/an-online-learning-experience-simulating-video-telehealth-with-older-adults-student-perceptions
#35
JOURNAL ARTICLE
Megan E Gately, Scott A Trudeau
Older adults are an underserved population with a broad-spectrum of care needs due to multi-morbidity, including increasing rates of mental health conditions. Though a prime target for tele-behavioral health due to access barriers, older adults face a persistent digital divide that necessitates clinician training and education to ensure interprofessional tele-behavioral health is tailored to their needs. This paper presents findings from a simulation learning program designed to teach students about the role of video telehealth with populations with diverse needs...
2024: Journal of Technology in Behavioral Science
https://read.qxmd.com/read/38585263/facial-palsy-after-administration-of-immune-checkpoint-inhibitors-case-report-literature-review-and-clinical-care-management
#36
Essia Mezni, Giovanni Corazza, Roxane Mari, Stephanie Coze, Nathalie Charrier, Brice Chanez, Anne Sophie Chretien, Philippe Rochigneux
Neurological immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI) are rare complications of immunotherapy, particularly dreadful for patients and clinical teams. Indeed, neurological irAEs are potentially severe and their diagnosis require prompt recognition and treatment. Additionally, the spectrum of neurological irAEs is broad, affecting either neuromuscular junction, peripheral or central nervous system. Here, we described the case of a 55-year man with metastatic melanoma, facing a brutal right peripheral cerebral palsy after his third ipilimumab/nivolumab infusion...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38585154/accuracy-of-an-artificial-intelligence-as-a-medical-device-as-part-of-a-uk-based-skin-cancer-teledermatology-service
#37
JOURNAL ARTICLE
Helen Marsden, Polychronis Kemos, Marcello Venzi, Mariana Noy, Shameera Maheswaran, Nicholas Francis, Christopher Hyde, Daniel Mullarkey, Dilraj Kalsi, Lucy Thomas
INTRODUCTION: An artificial intelligence as a medical device (AIaMD), built on convolutional neural networks, has demonstrated high sensitivity for melanoma. To be of clinical value, it needs to safely reduce referral rates. The primary objective of this study was to demonstrate that the AIaMD had a higher rate of correctly classifying lesions that did not need to be referred for biopsy or urgent face-to-face dermatologist review, compared to teledermatology standard of care (SoC), while achieving the same sensitivity to detect malignancy...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38580036/major-depressive-disorder-recognition-by-quantifying-eeg-signal-complexity-using-proposed-aplzc-and-awplzc
#38
JOURNAL ARTICLE
Xianyun Kang, Xiaoya Liu, Sitong Chen, Wenquan Zhang, Shuang Liu, Dong Ming
BACKGROUND: Seeking objective quantitative indicators is important for accurately recognizing major depressive disorder (MDD). Lempel-Ziv complexity (LZC), employed to characterize neurological disorders, faces limitations in tracking dynamic changes in EEG signals due to defects in the coarse-graining process, hindering its precision for MDD objective quantitative indicators. METHODS: This work proposed Adaptive Permutation Lempel-Ziv Complexity (APLZC) and Adaptive Weighted Permutation Lempel-Ziv Complexity (AWPLZC) algorithms by refining the coarse-graining process and introducing weight factors to effectively improve the precision of LZC in characterizing EEGs and further distinguish MDD patients better...
April 3, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38578851/a-closed-form-pairwise-solution-to-local-non-rigid-structure-from-motion
#39
JOURNAL ARTICLE
Shaifali Parashar, Yuxuan Long, Mathieu Salzmann, Pascal Fua
A recent trend in Non-Rigid Structure-from-Motion (NRSfM) is to express local, differential constraints between pairs of images, from which the surface normal at any point can be obtained by solving a system of polynomial equations. While this approach is more successful than its counterparts relying on global constraints, the resulting methods face two main problems: First, most of the equation systems they formulate are of high degree and must be solved using computationally expensive polynomial solvers...
April 4, 2024: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://read.qxmd.com/read/38576358/duration-of-face-mask-exposure-matters-evidence-from-swiss-and-brazilian-kindergartners-ability-to-recognise-emotions
#40
JOURNAL ARTICLE
Ebru Ger, Mirella Manfredi, Ana Alexandra Caldas Osório, Camila Fragoso Ribeiro, Alessandra Almeida, Annika Güdel, Marta Calbi, Moritz M Daum
Wearing facial masks became a common practice worldwide during the COVID-19 pandemic. This study investigated (1) whether facial masks that cover adult faces affect 4- to 6-year-old children's recognition of emotions in those faces and (2) whether the duration of children's exposure to masks is associated with emotion recognition. We tested children from Switzerland ( N  = 38) and Brazil ( N  = 41). Brazil represented longer mask exposure due to a stricter mandate during COVID-19...
April 5, 2024: Cognition & Emotion
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