keyword
MENU ▼
Read by QxMD icon Read
search

Epididymis

keyword
https://www.readbyqxmd.com/read/27908670/proteome-of-the-rete-testis-fluid-from-tropically-adapted-morada-nova-rams
#1
Mauricio Fraga van Tilburg, Solange Damasceno Sousa, Révila Bianca Ferreira de Melo, Frederico B Moreno, Ana Cristina Monteiro-Moreira, Renato A Moreira, Arlindo de Alencar Moura
The rete testis has a close relationship with sperm development and may have other functions besides serving as an intercalated channel. The aim of this study was to identify and characterize the proteins of rete testis fluid (RTF) from tropically-adapted Morada Nova rams. Testicles obtained from six Morada Nova rams were dissected and the head of the epididymis was separated to access the efferent ducts. Rete testis fluid was obtained by gentle massage of the testis. The fluid was centrifuged to remove cell debris and sperm...
November 22, 2016: Animal Reproduction Science
https://www.readbyqxmd.com/read/27908416/suppression-of-the-brain-pituitary-testicular-axis-function-following-acute-arsenic-and-manganese-co-exposure-and-withdrawal-in-rats
#2
Isaac A Adedara, Amos O Abolaji, Ifeoluwa O Awogbindin, Ebenezer O Farombi
Despite the fact that most environmental exposures to metals do not occur in isolation, the combined effects of metal mixtures on brain-pituitary-gonadal axis are poorly known. The present study investigated the impacts of co-exposure to arsenic (As) and manganese (Mn) on sperm characteristics, reproductive hormones and selected oxidative stress indices in the brain, testes and epididymis of rats following exposure for 15 consecutive days to 60mg/L of AsO2Na and 30mg/L of MnCl2 in drinking water. The results showed that while the brain weight remained unaffected, the fluid intake and the weights of testes and epididymis significantly (p<0...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27906723/safety-and-outcome-measures-of-first-in-human-intraperitoneal-%C3%AE-radioimmunotherapy-with-212pb-tcmc-trastuzumab
#3
Ruby F Meredith, Julien J Torgue, Tania A Rozgaja, Eileen P Banaga, Patty W Bunch, Ronald D Alvarez, J Michael Straughn, Michael C Dobelbower, Andrew M Lowy
PURPOSE: One-year monitoring of patients receiving intraperitoneal (IP) Pb-TCMC-trastuzumab to provide long-term safety and outcome data. A secondary objective was to study 7 tumor markers for correlation with outcome. METHODS: Eighteen patients with relapsed intra-abdominal human epidermal growth factor receptor-2 expressing peritoneal metastases were treated with a single IP infusion of Pb-TCMC-trastuzumab, delivered <4 h after 4 mg/kg IV trastuzumab. Seven tumor markers were studied for correlation with outcome...
November 30, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27899969/diagnostic-usefulness-of-the-risk-of-ovarian-malignancy-algorithm-using-the-electrochemiluminescence-immunoassay-for-he4-and-the-chemiluminescence-microparticle-immunoassay-for-ca125
#4
Anita Chudecka-Głaz, Aneta Cymbaluk-Płoska, Katarzyna Luterek-Puszyńska, Janusz Menkiszak
The present study aimed to investigate the usefulness of the Risk of Ovarian Malignancy Algorithm (ROMA) in the preoperative stratification of patients with ovarian tumors using a novel combination of laboratory tests. The study group (n=619) consisted of 354 premenopausal and 265 postmenopausal patients. The levels of carbohydrate antigen 125 (CA125) and human epididymis protein 4 (HE4) were determined, and ROMA calculations were performed for each pre- and postmenopausal patient. HE4 levels were determined using an electrochemiluminescence immunoassay, while CA125 levels were determined by a chemiluminescence microparticle immunoassay...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27892862/melamine-negatively-affects-testosterone-synthesis-in-mice
#5
Jiarui Sun, Yinan Cao, Xinchen Zhang, Qiling Zhao, Endong Bao, Yingjun Lv
Several studies have found that melamine causes damage to the testes, epididymis and sperm. However, few studies have investigated the effect of melamine on the synthesis of testosterone, which plays an import role in testicular development and spermatogenesis. In present study, mice were orally administrated with 2, 10 or 50mg/kg of melamine for 28days. In these groups, various abnormalities were observed including disruption of the seminiferous tubule structure, an increased necrotic germ cells and sperm abnormalities, and a reduced sperm count...
October 13, 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27892789/4-vinylcyclohexene-diepoxide-disrupts-sperm-characteristics-endocrine-balance-and-redox-status-in-testes-and-epididymis-of-rats
#6
Isaac A Adedara, Amos O Abolaji, Emmanuel O Ladipo, Ore J Fatunmibi, Ayodeji O Abajingin, Ebenezer O Farombi
OBJECTIVES: Exposure to 4-vinylcyclohexene diepoxide (VCD) was reported to induce testicular germ cell toxicity in rodents. However, there is paucity of information on the precise biochemical and molecular mechanisms of VCD-induced male reproductive toxicity. METHODOLOGY: This study investigated the influence of VCD on testicular and epidydimal functions following oral exposure of Wistar rats to VCD at 0, 100, 250 and 500 mg/kg for 28 consecutive days. RESULTS: Administration of VCD significantly decreased the body weight gain and organo-somatic indices of the testes and epididymis...
November 28, 2016: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/27888566/functional-expression-of-g-protein-coupled-receptor-30-in-immature-rat-epididymal-epithelium
#7
Xiaonian Cao, Jiehong Huang, Geng Zhang, Wulin Zuo, Chongfeng Lan, Qing Sun, Dengliang Yang, Dongdong Gao, Christopher H K Cheng, Wen-Liang Zhou
The aim of this study is to investigate the functional role of G protein-coupled receptor 30 (GPR30) in the epididymis. We found that GPR30 is expressed in the epithelium of the immature rat epididymis and is involved in chloride secretion into the caudal epididymis lumen. The short-circuit current (Isc) experiments showed that in primary cultured caudal epididymis epithelium, activation of GPR30 by its specific agonist G1 induced a mono-phasic current increase, and G15, the specific antagonist of GPR30, could completely inhibit the current induced by G1...
November 26, 2016: Cell Biology International
https://www.readbyqxmd.com/read/27888149/in-patients-with-obstructive-azoospermia-testicular-spermatozoa-are-of-better-quality-than-epididymal-spermatozoa
#8
I Hammoud, M Bailly, M Bergere, R Wainer, V Izard, F Vialard, J Selva, F Boitrelle
OBJECTIVE: To assess sperm quality as a function of the sampling site (testis or epididymis) in obstructive azoospermia (OA). MATERIALS AND METHODS: DNA fragmentation rates in spermatozoa sampled from the testis and epididymis (from patients with different aetiologies of OA) were assessed in a dUTP nick end labelling (TUNEL) assay. RESULTS: Twenty-one OA patients were included: 5 had congenital bilateral absence of the vas deferens, 8 had genital tract infections and 8 had idiopathic OA...
November 22, 2016: Urology
https://www.readbyqxmd.com/read/27887012/epididymal-papillary-cystadenocarcinoma-metastasising-to-the-testis-in-a-patient-with-infertility-managed-with-onco-microtese
#9
Nisha Pindoria, Yurina Miki, Andrea Tay, Ashish Chandra, Christopher Anderson, Evangelos Zacharakis, Majed Shabbir
Papillary cystadenomas of the epididymis are known to occur in association with Von Hippel-Lindau (VHL) disease. The development of a papillary cystadenocarcinoma, its malignant counterpart, is rare with only a few sporadic cases reported in the literature. Metastatic deposits are exceedingly uncommon; in fact, only a single case report has documented metastases to the paraureteral region, but metastases to the testis have never been reported. A 43-year-old gentleman with VHL disease presented with non-obstructive azoospermia, a right epididymal mass, and an atrophic surgically corrected undescended left testis...
November 24, 2016: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/27885104/could-vitamin-c-and-zinc-chloride-protect-the-germ-cells-against-sodium-arsenite
#10
L S Altoé, I B Reis, Mlm Gomes, H Dolder, Jc Monteiro Pirovani
Arsenic (As) is commonly associated with natural and human processes such as volcanic emissions, mining and herbicides production, being an important pollutant. Several studies have associated As intake with male fertility reduction, thus the aim of the present study was to evaluate whether vitamin C and/or zinc would counteract As side effects within the testicles. Adult male Wistar rats were divided into six experimental groups: control, sodium arsenite (5 mg/kg/day), vitamin C (100 mg/kg/day), zinc chloride (ZnCl2; 20 mg/kg/day), sodium arsenite + vitamin C and sodium arsenite + ZnCl2 Testicles and epididymis were harvested and either frozen or routinely processed to be embedded in glycol methacrylate resin...
November 24, 2016: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/27876458/relative-abundance-of-g-protein-coupled-receptor-30-and-localization-in-testis-and-epididymis-of-sheep-at-different-developmental-stages
#11
Peiyao Lu, Fuchuan Wang, Xianyi Song, Yang Liu, Kai Zhang, Ningxian Cao
The G protein-coupled receptor 30 (GPR30) is a transmembrane estrogen receptor that binds to estrogen, and has been confirmed to have an important role in testicular cell proliferation and development. The main objective of this study was to examine GPR30 gene expression and localization in the testis and epididymis of sheep at different developmental stages. Testes, including the epididymis, were collected from Polled Dorset x Mongolian cross rams at one (n=4; wt), three (n=4; wt), six (n=4; wt), nine (n=4; wt) and 12 (n=4; wt) months of age...
October 11, 2016: Animal Reproduction Science
https://www.readbyqxmd.com/read/27871980/low-dose-assessment-of-the-carcinogenicity-of-furan-in-male-f344-n-nctr-rats-in-a-2-year-gavage-study
#12
Linda S Von Tungeln, Nigel J Walker, Greg R Olson, Maria C B Mendoza, Robert P Felton, Brett T Thorn, M Matilde Marques, Igor P Pogribny, Daniel R Doerge, Frederick A Beland
Furan is a volatile organic chemical that is a contaminant in many common foods. Furan is hepatocarcinogenic in mice and rats; however, the risk to humans from dietary exposure to furan cannot be estimated accurately because the lowest tested dose of furan in a 2-year bioassay in rats gave nearly a 100% incidence of cholangiocarcinoma. To provide bioassay data that can be used in preparing risk assessments, the carcinogenicity of furan was determined in male F344/N Nctr rats administered 0, 0.02, 0.044, 0.092, 0...
November 18, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27871721/roles-of-human-epididymis-protein-4-carbohydrate-antigen-125-inhibin-b-and-anti-m%C3%A3-llerian-hormone-in-the-differential-diagnosis-and-follow-up-of-ovarian-granulosa-cell-tumors
#13
Ulla-Maija Haltia, Marianne Hallamaa, Johanna Tapper, Johanna Hynninen, Henrik Alfthan, Bhanu Kalra, Olli Ritvos, Markku Heikinheimo, Leila Unkila-Kallio, Antti Perheentupa, Anniina Färkkilä
OBJECTIVE: Evaluation of circulating tumor markers in ovarian cancer is crucial for optimal patient care. The goal of this study was to verify the most accurate circulating tumor markers for the diagnosis and follow-up of adult-type granulosa cell tumors (AGCTs). METHODS: The levels of circulating human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125), together with AGCT markers inhibin B and anti-Müllerian hormone (AMH), were measured in 135 samples from AGCT patients, 37 epithelial ovarian carcinoma (EOC) patients, and 40 endometrioma (ENDO) patients...
November 18, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27865411/low-levels-of-apoptotic-like-changes-in-fresh-and-cryopreserved-feline-spermatozoa-collected-from-the-urethra-and-epididymis
#14
Sylwia Prochowska, Wojciech Niżański, Agnieszka Partyka
The aim of this study was to examine apoptotic markers in fresh and frozen-thawed feline spermatozoa collected via urethral catheterization and epididymal slicing. Caspase activation, DNA fragmentation, and phosphatidylserine externalization were evaluated using flow cytometry in sperm cells from both sources before and after cryopreservation. The study revealed no differences between urethral and epididymal spermatozoa, both in fresh and frozen-thawed samples. The level of apoptotic changes in sperm cells in fresh feline semen was low: 0...
January 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/27862665/role-of-human-epididymis-protein-4-in-chemoresistance-and-prognosis-of-epithelial-ovarian-cancer
#15
Seungho Lee, Seowon Choi, Yookyung Lee, Donghae Chung, Suntaek Hong, Nohhyun Park
AIM: Human epididymis protein 4 (HE4) is a novel biomarker for epithelial ovarian cancer. This study was designed to evaluate the role of HE4 in chemo-response against anti-cancer drugs and prognosis of epithelial ovarian cancer. METHODS: HE4-depleted cells and HE4-overexpressing cells were generated. The effect of HE4 gene silencing and overexpression was examined using a cell viability assay after exposure to chemotherapeutic agents and the signaling pathway. We studied the expression of HE4 in ovarian cancer tissue and the prognostic significance...
November 12, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27862454/effect-of-testicular-tissue-lysate-on-developmental-competence-of-porcine-oocytes-matured-and-fertilized-in-vitro
#16
A K Singh, S Naskar, B Saikia, Y Vashi, S Gupta, S Banik, M K Tamuli, V Pande, D K Sarma, S K Dhara
The objective of the present study was to investigate the effect of testicular tissue lysate (TTL) on developmental competence of germinal vesicle (GV) stage porcine oocytes. Two types of TTL were prepared through repeated freeze-thaw in liquid nitrogen, one from whole testicular tissue (wTTL) and other from either of four different sections of testes, namely just beneath the tunica albuginea (TA), from the transitional area between the seminiferous cord/tubules and the mediastinum testis (TR) and from the intermediate area (parenchymal tissue origin) and CE (cauda epididymis origin)...
November 15, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27862401/identification-and-changes-in-the-seasonal-concentrations-of-heat-shock-proteins-in-roe-deer-capreolus-capreolus-epididymides
#17
A M Majewska, W Kordan, M Koziorowska-Gilun, P Wysocki
Heat shock proteins (HSPs) act as molecular chaperones with important regulatory functions. HSPs are considered to be essential factors in animal reproduction. In view of seasonal variations in the secretory activity of the reproductive tract of mature roe deer (Capreolus capreolus), the aims of this study were to identify HSPs in the epididymides and compare the expression of the identified proteins in three periods of the reproductive season. Two-dimensional polyacrylamide gel electrophoresis revealed the highest number of polypeptides in homogenates of epididymal tissues and in caput, corpus and cauda epididymal fluids throughout the reproductive season...
November 13, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27859687/he4-as-a-predictor-of-adjuvant-chemotherapy-resistance-and-survival-in-patients-with-epithelial-ovarian-cancer
#18
Mona Aarenstrup Karlsen, Claus Høgdall, Lotte Nedergaard, Kira Philipsen Prahm, Nikoline Marie Schou Karlsen, Anne Weng Ekmann-Gade, Tine Henrichsen Schnack, Tim Svenstrup Poulsen, Ib Jarle Christensen, Estrid Høgdall
The aim of this study was to investigate the value of serum human epididymis protein 4 (HE4) and HE4 tissue protein expression to predict tumor resistance to adjuvant chemotherapy, progression-free survival (PFS), and overall survival in patients with epithelial ovarian cancer (EOC). Consecutive inclusion of 198 patients diagnosed with EOC was conducted. Blood samples were collected prior to surgery and tissue samples during surgery. Patient data were registered prospectively in the Danish Gynecologic Cancer Database...
December 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27857462/sclerosing-liposarcoma-of-epididymis-role-of-chemical-shift-magnetic-resonance-imaging
#19
Subramaniyan Ramanathan, Vineetha Raghu, Devendra Kumar, Venkata R P Sempiege
Sclerosing liposarcoma of epididymis is a rare extratesticular scrotal tumor with variable prognosis. Ultrasonography is the initial imaging modality of choice for the evaluation of scrotal mass and helps to differentiate testicular and extratesticular masses, thereby narrowing down the differential diagnosis. Magnetic resonance imaging with its excellent soft tissue resolution can help in the further characterization of the nature of the tumor. In this case report, we highlight the role of chemical shift imaging in making a confident preoperative diagnosis of liposarcoma thereby guiding optimal and timely management...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27852932/epididymis-like-tubules-in-adult-renal-hypodysplasia-immunohistochemical-features-indicate-a-mesonephric-origin
#20
Madhavi A Naik, Sanjay A Pai
We report the presence of epididymis-like tubules in unilateral renal hypodysplasia in 3 adult men. Microscopy showed dilated tubules lined by ciliated columnar epithelium and smaller basal cells, morphologically resembling epididymal tubules. Small tubules lined by cuboidal epithelium were also present in all cases, with glomeruli in 2 cases. The epididymis-like tubules expressed CD10, CK7, PAX8, and AR in the luminal epithelium, while the basal cells were positive for p63, CK7, and focally for CD10. The smooth muscle bundles around the epididymis-like tubules were focally AR and WT1 (cytoplasmic) positive...
November 16, 2016: International Journal of Surgical Pathology
keyword
keyword
24365
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"