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https://www.readbyqxmd.com/read/29679301/contemporary-antithrombotic-treatment-in-patients-with-non-valvular-atrial-fibrillation-undergoing-percutaneous-coronary-intervention-rationale-and-design-of-the-greek-antiplatelet-atrial-fibrillation-grape-af-registry
#1
Ioanna Xanthopoulou, Vasiliki-Maria Dragona, Periklis Davlouros, Costas Tsioufis, Efstathios Iliodromitis, Dimitrios Alexopoulos
BACKGROUND: Approximately 5 to 7% of patients undergoing percutaneous coronary intervention (PCI) for the treatment of coronary artery disease require chronic oral anticoagulation (OAC) on top of aspirin and a P2Y12 receptor antagonist, mainly due to non-valvular atrial fibrillation (AF). The advent of non-vitamin K antagonist oral anticoagulants (NOACs) increased treatment options, while there is cumulative evidence that dual combination of a NOAC and a P2Y12 receptor antagonist attenuates risk of bleeding, compared to traditional triple therapy, consisting of a vitamin K antagonist (VKA), aspirin, and a P2Y12 receptor antagonist, without significantly compromising efficacy...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29678994/can-exercise-delay-transition-to-active-therapy-in-men-with-low-grade-prostate-cancer-a-multicentre-randomised-controlled-trial
#2
Daniel A Galvão, Dickon Hayne, Mark Frydenberg, Suzanne K Chambers, Dennis R Taaffe, Nigel Spry, Paul A Scuffham, Robert S Ware, Nicolas H Hart, Robert U Newton
INTRODUCTION: Active surveillance is a strategy for managing low-risk, localised prostate cancer, where men are observed with serial prostate-specific antigen assessments to identify signs of disease progression. Currently, there are no strategies to support active surveillance compliance nor are there interventions that can prevent or slow disease progression, ultimately delaying transition to active treatment before it is clinically required. Recently, we proposed that exercise may have a therapeutic potential in delaying the need for active treatment in men on active surveillance...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678296/impact-of-a-low-intensity-and-broadly-inclusive-ed-care-coordination-intervention-on-linkage-to-primary-care-and-ed-utilization
#3
Sean D Foster, Kim Hart, Christopher J Lindsell, Christopher N Miller, Michael S Lyons
OBJECTIVE: We aim to evaluate the effectiveness of a broadly inclusive, comparatively low intensity intervention linking ED patients to a primary care home. METHODS: This retrospective cohort study evaluated ED patients referred for primary care linkage in a large, urban, academic ED. A care coordination specialist performed a brief interview to gauge access barriers and provide a clinic referral with optional scheduling assistance. Data were abstracted from program records and the electronic medical record...
April 5, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29677141/thematic-analysis-of-medical-notes-offers-preliminary-insight-into-precipitants-for-asian-suicide-attempters-an-exploratory-study
#4
Carol C Choo, Roger C Ho, André A D Burton
One important dynamic risk factor for suicide assessment includes suicide precipitant. This exploratory study used a qualitative paradigm to look into the themes surrounding precipitants for suicide attempts in Singapore. Medical records related to suicide attempters who were admitted to the emergency department of a large teaching hospital in Singapore over a three year period were subjected to analysis. A total of 666 cases were examined (69.2% females; 63.8% Chinese, 15% Malays, 15.8% Indians), ages ranged from 10 years old to 85 years old (Mean = 29...
April 20, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29676138/-clinical-experience-and-academic-thoughts-of-professor-liu-feng-bin-on-case-series-of-gastroesophageal-reflux-disease-based-on-data-mining
#5
Zheng-Kun Hou, Ji-Ping Li, Zhuo-Qun Chen, Feng-Bin Liu
To analyze and summarize Professor LIU Feng-bin's clinical experience and academic thoughts on gastroesophageal reflux disease (GERD), the study group adopted the retrospective study for case series and expert interview, extracted the retrospective data, including the herbs, diseases, syndrome type, medical expense and quantity of herbs of GERD patients attended the First Affiliated Hospital of Guangzhou University of Chinese Medicine. Statistical description and binary Logistic regression were used for the identification and modification of syndrome type and initial core herbs...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29675547/the-association-between-fatigue-and-pain-symptoms-and-decreased-physical-activity-after-cancer
#6
Sally A D Romero, Lee Jones, Joshua M Bauml, Q Susan Li, Roger B Cohen, Jun J Mao
PURPOSE: Patients with cancer frequently experience symptoms such as fatigue and pain that can influence their ability to maintain their usual physical activity (PA). This study aimed to evaluate whether symptoms of fatigue and pain are associated with decreased PA among patients with cancer. METHODS: We recruited patients with a cancer diagnosis from one academic medical center and 11 affiliated community hospitals to participate in a cross-sectional survey. Multivariate logistic regression models were used to examine the association between symptoms, demographics, and clinical characteristics and decreased PA since cancer diagnosis...
April 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29672647/mapping-the-knowledge-structure-of-frailty-in-journal-articles-by-text-network-analysis
#7
Youngji Kim, Soong-Nang Jang
BACKGROUNDS: This study was to understand the trends of frailty research and networking features of keywords from the academic articles focusing on frailty in the last four decades. METHOD: Keywords were extracted from articles (n = 6,424) retrieved from Web of Science, from 1981 to April 2016, using Bibexcel, and a social network analysis was conducted using Net Miner. RESULTS: The core-keywords of research on frailty are constantly changing over the last 40 years...
2018: PloS One
https://www.readbyqxmd.com/read/29672526/structured-patient-handoff-on-an-internal-medicine-ward-a-cluster-randomized-control-trial
#8
Penny Tam, Aman P Nijjar, Mark Fok, Chris Little, Alexandra Shingina, Jesse Bittman, Rashmi Raghavan, Nadia A Khan
BACKGROUND: The effect of a multi-faceted handoff strategy in a high volume internal medicine inpatient setting on process and patient outcomes has not been clearly established. We set out to determine if a multi-faceted handoff intervention consisting of education, standardized handoff procedures, including fixed time and location for face-to-face handoff would result in improved rates of handoff compared with usual practice. We also evaluated resident satisfaction, health resource utilization and clinical outcomes...
2018: PloS One
https://www.readbyqxmd.com/read/29672508/the-gender-gap-in-science-how-long-until-women-are-equally-represented
#9
Luke Holman, Devi Stuart-Fox, Cindy E Hauser
Women comprise a minority of the Science, Technology, Engineering, Mathematics, and Medicine (STEMM) workforce. Quantifying the gender gap may identify fields that will not reach parity without intervention, reveal underappreciated biases, and inform benchmarks for gender balance among conference speakers, editors, and hiring committees. Using the PubMed and arXiv databases, we estimated the gender of 36 million authors from >100 countries publishing in >6000 journals, covering most STEMM disciplines over the last 15 years, and made a web app allowing easy access to the data (https://lukeholman...
April 2018: PLoS Biology
https://www.readbyqxmd.com/read/29672234/transgender-college-students-academic-resilience-and-striving-to-cope-in-the-face-of-marginalized-health
#10
Jenna B Messman, Leigh A Leslie
OBJECTIVE: To examine health behavior and outcome disparities between transgender, female, and male participants in a national sample of US college students. Participants and Method Summary: Analyses utilized secondary data from 32,964 undergraduate and graduate students responding to the Fall 2013 American College Health Association-National College Health Assessment; 65.8% were female, 0.4% were transgender, 67.9% were white, and 90.4% were heterosexual. RESULTS: Transgender students reported more mental health diagnoses, trauma, and suicidality; experienced more violence and less safety, reported more sex partners and sexually transmitted infections (STIs); higher rates of illicit and non-prescription substance use and binge drinking use while engaging in less harm reduction behavior; and reported more barriers to academic success...
April 19, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29670557/teacher-evaluated-self-regulation-is-related-to-school-achievement-and-influenced-by-parental-education-in-schoolchildren-aged-8-12-a-case-control-study
#11
Marleen A J van Tetering, Renate H M de Groot, Jelle Jolles
There are major inter-individual differences in the school achievements of students aged 8-12. The determinants of these differences are not known. This paper investigates two possible factors: the self-regulation of the student and the educational levels obtained by their parents. The study first investigates whether children with high and low academic achievement differ in their self-regulation. It then evaluates whether there are differences in the self-regulation of children with high and moderate-to-low level of parental education (LPE)...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29669430/providing-palliative-care-in-the-medical-icu-a-qualitative-study-of-micu-physicians-beliefs-and-practices
#12
Brittany Gatta, Jessica Turnbull
CONTEXT: With the current and projected shortage of palliative care (PC) specialists, an integrative model of PC will be needed to meet the needs of patients in intensive care units (ICUs). Prior studies of PC interventions suggest that success depends upon meeting the needs of individual institutions or ICUs. OBJECTIVE: The objective of this study was to qualitatively explore the beliefs and practices of one institution's medical ICU (MICU) physicians in regard to providing an integrative model of PC...
January 1, 2018: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29666161/implementation-of-the-sepsis-risk-calculator-at-an-academic-birth-hospital
#13
Miren B Dhudasia, Sagori Mukhopadhyay, Karen M Puopolo
BACKGROUND: Multivariate predictive models for estimating the risk of neonatal early-onset sepsis (EOS) are available as a Web-based sepsis risk calculator (SRC) and may reduce the proportion of newborns empirically treated with antibiotics after birth. EOS risk assessment based on such models would require workflow changes at most birth hospitals. METHODS: A multidisciplinary team of obstetric, neonatal, and information technology staff at a large, academic, birth hospital collaborated to implement the SRC...
April 17, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29664875/do-not-resuscitate-orders-in-the-neonatal-icu-experiences-and-beliefs-among-staff
#14
Bonnie H Arzuaga, C Lydia Wraight, Christy L Cummings, Wenyang Mao, David Miedema, Dara D Brodsky
OBJECTIVES: Studies in adult patients have shown that do-not-resuscitate orders are often associated with decreased medical intervention. In neonatology, this phenomenon has not been investigated, and how do-not-resuscitate orders potentially affect clinical care is unknown. DESIGN: Retrospective medical record data review and staff survey responses about neonatal ICU do-not-resuscitate orders. SETTING: Four academic neonatal ICUs. SUBJECTS: Clinical staff members working in each neonatal ICU...
April 16, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29661634/assessing-patient-risk-of-central-line-associated-bacteremia-via-machine-learning
#15
Cole Beeler, Lana Dbeibo, Kristen Kelley, Levi Thatcher, Douglas Webb, Amadou Bah, Patrick Monahan, Nicole R Fowler, Spencer Nicol, Alisa Judy-Malcolm, Jose Azar
BACKGROUND: Central line-associated bloodstream infections (CLABSIs) contribute to increased morbidity, length of hospital stay, and cost. Despite progress in understanding the risk factors, there remains a need to accurately predict the risk of CLABSIs and, in real time, prevent them from occurring. METHODS: A predictive model was developed using retrospective data from a large academic healthcare system. Models were developed with machine learning via construction of random forests using validated input variables...
April 13, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29661279/sources-of-distress-among-patients-undergoing-surgery-for-colorectal-cancer-a-qualitative-study
#16
Jonathan S Abelson, Alanna Chait, Megan J Shen, Mary Charlson, Anna Dickerman, Heather L Yeo
BACKGROUND: Distress is common among cancer and surgical patients and can lead to worse outcomes if untreated. The objective of this study was to explore sources of distress among colorectal cancer patients undergoing surgery. MATERIALS AND METHODS: This was a qualitative study using in-depth, semistructured, one-on-one interviews in an academic setting. Patients were recruited if they had a pathologically confirmed diagnosis of colon or rectal cancer. Purposive sampling was used to recruit patients who were about to undergo (preoperative), or had recently undergone (postoperative), curative resection for colorectal cancer...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29661239/neonatal-care-practices-in-sub-saharan-africa-a-systematic-review-of-quantitative-and-qualitative-data
#17
REVIEW
Margaret Bee, Anushree Shiroor, Zelee Hill
BACKGROUND: Recommended immediate newborn care practices include thermal care (immediate drying and wrapping, skin-to-skin contact after delivery, delayed bathing), hygienic cord care and early initiation of breastfeeding. This paper systematically reviews quantitative and qualitative data from sub-Saharan Africa on the prevalence of key immediate newborn care practices and the factors that influence them. METHODS: Studies were identified by searching relevant databases and websites, contacting national and international academics and implementers and hand-searching reference lists of included articles...
April 16, 2018: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29661069/the-black-cloud-phenomenon-in-hand-surgery
#18
Emily Zhao, Nathan Tiedeken, William Wang, John Fowler
BACKGROUND: The term black cloud for a surgeon is generally used to describe someone who is unusually busy compared with his or her counterparts, and it is a superstition that tends to pervade the medical world. The purpose of this study is to investigate whether black clouds exist in hand surgery. METHODS: We examined one academic year's worth of hand surgery-specific call at a level I trauma center and tabulated the number of hand-related patient transfers and add-on cases per surgeon...
April 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29660957/a-systematic-review-and-meta-analysis-of-educational-interventions-for-children-and-adolescents-with-acquired-brain-injury
#19
Mark A Linden, Ann E Glang, Audrey McKinlay
BACKGROUND: Children with brain injuries face significant challenges in their recovery. One of the greatest is transitioning from hospital/home to school where they face issues such as reintegration, lack of understanding and catching up with missed work. Many children struggle with their altered circumstances and require additional supports to meet the academic demands of systems which are ill equipped to teach them. OBJECTIVE: To summarise the best available evidence for the use of educational interventions to improve academic attainment in childhood survivors of acquired brain injury (ABI)...
April 7, 2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29660573/midwifery-in-iceland-from-vocational-training-to-university-education
#20
Olof A Olafsdottir, Hildur Kristjansdottir, Berglind Halfdansdottir, Helga Gottfredsdottir
Midwifery education is a foundation for health professionals' competence in providing quality healthcare for the benefit of women, their families and society. This paper describes midwifery and the development of midwifery education in Iceland. It examines policy and extensive reforms, from hospital-based vocational training in midwifery to an academic university education, and the impact on the scope of midwifery practice in Iceland. The university-based programme, with its emphasis on autonomy of the midwife, seems to have affected the context of home birth and strengthened midwives' role in primary healthcare...
April 3, 2018: Midwifery
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