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https://www.readbyqxmd.com/read/28734229/effects-of-dietary-starch-types-on-early-postmortem-muscle-energy-metabolism-in-finishing-pigs
#1
Y J Li, T Gao, J L Li, L Zhang, F Gao, G H Zhou
This study aimed to investigate the effects of different dietary starch types on early postmortem muscle energy metabolism in finishing pigs. Ninety barrows (68.0±2.0kg) were randomly allotted to three experimental diets with five replicates of six pigs, containing pure waxy maize starch (WMS), nonwaxy maize starch (NMS), and pea starch (PS) (amylose/amylopectin were 0.07, 0.19 and 0.28 respectively). Compared with the WMS diet, pigs fed the PS diet exhibited greater creatine kinase activity, higher adenosine triphosphate and adenosine diphosphate contents, lower phosphocreatine (PCr), adenosine monophosphate and glycogen contents, and lower glycolytic potential (P<0...
July 12, 2017: Meat Science
https://www.readbyqxmd.com/read/28734210/effects-analysis-of-substituent-characteristics-and-solvents-on-the-photodegradation-of-polybrominated-diphenyl-ethers
#2
Long Jiang, Youli Qiu, Yu Li
The ultraviolet spectra and electron transition information of 209 polybrominated diphenyl ethers (PBDEs) in gas were first calculated via time-dependent density functional theory using Gaussian 09 software. The main and second-order interactional effects of substituent characteristics on the photodegradation of PBDEs were then analysed using a full factorial experimental design. Solvent effects were considered to research the effect and promotion mechanism of solvent molecules on the photodegradation of PBDEs compared with that in gas...
July 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28734208/effect-of-mutation-on-a%C3%AE-1-42-heme-complex-in-aggregation-mechanism-alzheimer-s-disease
#3
Subramaniam Boopathi, Ponmalai Kolandaivel
Amyloid β (Aβ) peptide aggregation is one of the root causes for Alzheimer's disease. Recently, experimental studies show that three active binding sites (His6, His13 and His14) of Aβ peptides were bound with heme to form Aβ-Heme complex, which leads to inhibit the aggregation process. We apply molecular dynamic simulation to investigate the aggregation pathways of Aβ-Heme peptides. The above three binding sites were mutated by Glycine residue individually and generate three complex systems such as Aβ(His6Gly)-Heme, Aβ(His13Gly)-Heme and Aβ(His14Gly)-Heme...
July 8, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28734205/identification-of-mycobacterium-tuberculosis-enoyl-acyl-carrier-protein-reductase-inhibitors-a-combined-in-silico-and-in-vitro-analysis
#4
Mohsin Y Lone, Mohd Athar, Vivek K Gupta, Prakash C Jha
Mycobacterium tuberculosis (Mtb), had developed evolutionary changes in its genome to adapt for survival and thereby generated multi-drug resistant strains. However, novel drug targets that remained unchanged for their biochemical role has impressed the research community to target such proteins. The comprehensive analysis of multiple protein targets has influenced us to make a consensus structural rule exploited by pharmacophore and other allied techniques from a large repository of protein structures. In this pursuit, we made a retrospective analysis of pharmacophores mapped from the tuberculosis structural proteome and identified unique patterns that can be employed for the novel molecules design...
July 14, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28734202/creating-institutional-flexibility-for-adaptive-water-management-insights-from-two-management-agencies
#5
Michael Peat, Katie Moon, Fiona Dyer, William Johnson, Susan J Nichols
Adaptive management is an experimental approach used by water management agencies around the world to manage and restore aquatic ecosystems. The effectiveness of the approach can often be constrained by inflexible institutional arrangements. In this paper we compare two cases where agencies have implemented adaptive management to manage and restore aquatic ecosystems. Our aim was to understand practitioners' perceptions of how institutional flexibility can be created for adaptive management. We interviewed 14 adaptive management practitioners working in the Murray-Darling Basin, Australia and 14 practitioners in Southern Florida, United States of America...
July 19, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28734188/the-effects-of-neurologic-assessment-e-learning-in-nurses
#6
Ji Yeon Shin, S Barry Issenberg, Young Sook Roh
BACKGROUND: A firm understanding of the preliminary assessment of a patient with neurological disorders is needed for ensuring optimal patient outcomes. OBJECTIVES: The purpose of this study is to evaluate the effects of using e-learning on neurologic assessment knowledge, ability, and self-confidence among nurses. DESIGN: This study used a non-equivalent control group pretest-posttest design. SETTINGS: Nurses working in the neurology and neurosurgery wards, Republic of Korea PARTICIPANTS: A convenience sample of 50 nurses was assigned to either the experimental group (n=24) or the control group (n=26)...
July 15, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28734114/effects-of-pomegranate-peel-extract-on-histopathology-testosterone-levels-and-sperm-of-testicular-torsion-detorsion-induced-in-adult-wistar-rats
#7
Mandana Beigi Boroujeni, Said Saied Shahrokhi, Mahdi Birjandi, Abolfazl Abbaszadeh, Fatemeh Beyranvand, Sakineh Hamoleh, Zohreh Zandbaf, Mohammadreza Gholami
Background In the present study, effects of pomegranate peel extract have been evaluated on decreasing the damage induced by testis torsion. Methods In this study, 30 adult Wistar rats were randomly divided into three groups of control, experimental (1) and experimental (2). CONTROL: no ischemia, received vehicle alone, exposed to sham operation. Experimental (1): Received the vehicle alone during ischemia followed by 60 days' reperfusion. Experimental (2): After performing ischemia reperfusion, 500 mg/kg of pomegranate peel extract has been used for 60 days...
July 22, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28732440/intravenous-injection-of-myelin-oligodendrocyte-glycoprotein-coated-plga-microparticles-have-tolerogenic-effects-in-experimental-autoimmune-encephalomyelitis
#8
Mehrdad Gholamzad, Masoumeh Ebtekar, Mehdi Shafiee Ardestani
The abnormal function of the T lymphocytes causes a range of autoimmune diseases, particularly multiple sclerosis; hence, several methods have been used to treat these disorders through the induction of antigen-specific tolerance in T cells. The present study aims to use a simple and low-cost method to produce poly (lactic-co-glycolic acid) (PLGA) nanoparticles for carrying antigens and inducing antigen-specific tolerance. In this study, PLGA nanoparticles were produced using the water/oil/water (W/O/W) method...
June 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28732394/surface-charge-effects-on-the-electro-orientation-of-insulating-boron-nitride-nanotubes-in-aqueous-suspension
#9
Semih Cetindag, Bishnu Tiwari, Dongyan Zhang, Yoke Khin Yap, Sangil Kim, Jerry W Shan
The alignment of hexagonal boron-nitride nanotubes (BNNTs) in aqueous KCl solutions under spatially uniform electric fields was examined experimentally, using direct optical visualization to probe the orientation dynamics of individual BNNTs for different electric-field frequencies. Different from most previously studied nanowires and nanotubes, BNNTs are wide-bandgap materials which are essentially insulating at room temperature. We analyze the electro-orientation of BNNTs in the general context of polarizable cylindrical particles in liquid suspensions, whose behavior can fall into different regimes, including alignment due to Maxwell-Wagner induced dipoles at high frequencies, and alignment due to fluid motion of the electrical double layer around the particles at lower frequencies...
May 29, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28732341/chirp-excitation
#10
Navin Khaneja
The paper describes the design of broadband chirp excitation pulses. We first develop a three stage model for understanding chirp excitation in NMR. We then show how a chirp π pulse can be used to refocus the phase of the chirp excitation pulse. The resulting magnetization still has some phase dispersion in it. We show how a combination of two chirp π pulses instead of one can be used to eliminate this dispersion, leaving behind a small residual phase dispersion. The excitation pulse sequence presented here allows exciting arbitrary large bandwidths without increasing the peak rf-amplitude...
July 13, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28732333/p-nitrophenol-degradation-by-electro-fenton-process-pathway-kinetic-model-and-optimization-using-central-composite-design
#11
J Meijide, E Rosales, M Pazos, M A Sanromán
The chemical process scale-up, from lab studies to industrial production, is challenging and requires deep knowledge of the kinetic model and the reactions that take place in the system. This knowledge is also useful in order to be employed for the reactor design and the determination of the optimal operational conditions. In this study, a model substituted phenol such as p-nitrophenol was degraded by electro-Fenton process and the reaction products yielded along the treatment were recorded. The kinetic model was developed using Matlab software and was based on main reactions that occurred until total mineralization which allowed predicting the degradation pathway under this advanced oxidation process...
July 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28732329/an-experimental-study-on-the-influence-of-water-stagnation-and-temperature-change-on-water-quality-in-a-full-scale-domestic-drinking-water-system
#12
Lj Zlatanović, J P van der Hoek, J H G Vreeburg
The drinking water quality changes during the transport through distribution systems. Domestic drinking water systems (DDWSs), which include the plumbing between the water meter and consumer's taps, are the most critical points in which water quality may be affected. In distribution networks, the drinking water temperature and water residence time are regarded as indicators of the drinking water quality. This paper describes an experimental research on the influence of stagnation time and temperature change on drinking water quality in a full-scale DDWS...
July 10, 2017: Water Research
https://www.readbyqxmd.com/read/28732318/the-experimental-tobacco-marketplace-ii-substitutability-and-sex-effects-in-dual-electronic-cigarette-and-conventional-cigarette-users
#13
Amanda J Quisenberry, Mikhail N Koffarnus, Leonard H Epstein, Warren K Bickel
AIM: The aim of the current study was to evaluate tobacco product purchasing in the Experimental: Tobacco Marketplace (ETM) among male and female smokers who also use e-cigarettes. We hypothesized a high substitution profile for e-cigarettes and that males would purchase more Snus than females. METHODS: The ETM is an online market used in clinical abuse liability research to mimic real-world purchasing patterns. Tobacco products, including each participant's usual choice of conventional and e-cigarettes, were presented along with a price and description of nicotine content...
July 5, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28732306/photostability-testing-using-online-reactor-hplc-hyphenation-and-mass-spectrometric-compound-identification-illustrated-by-ketoprofen-as-model-compound
#14
Jaber Assaf, Diego Zulkiewicz Gomes, Bernhard Wuest, Maria Kristina Parr
Investigations on the photochemical stability of pharmaceutical substances are mandatory in drug development and licensing as photo-induced degradation of an active pharmaceutical ingredient (API) may not only lead to decreased API concentrations but also to toxic or reactive products. Thus, the US Food and Drug Administration (FDA) and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) issued Guidance for Industry Q1B "Photostability Testing of New Drug Substances and Products" for testing of pure but also packed drugs...
July 8, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28732295/determination-of-54-pesticides-in-waters-of-the-iberian-douro-river-estuary-and-risk-assessment-of-environmentally-relevant-mixtures-using-theoretical-approaches-and-artemia-salina-and-daphnia-magna-bioassays
#15
Catarina Cruzeiro, Sofia Amaral, Eduardo Rocha, Maria João Rocha
As a case study, the estuary of the international Douro River (Iberian Peninsula) was sampled over a year (2010) at six sampling sites to determine the presence of 56 pesticides of different categories (insecticides, herbicides, and fungicides). 96% of measured pesticides were detected in 79% of the quantified samples. Individual average pesticide concentrations ranged from 39 to 1 265ng/L, indicating a ubiquitous presence of the selected compounds; moreover, twelve pesticides were above the 2013/39/EU Directive limits...
July 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28732281/epileptic-seizure-detection-in-eegs-signals-based-on-the-weighted-visibility-graph-entropy
#16
Zeynab Mohammadpoory, Mahda Nasrolahzadeh, Javad Haddadnia
PURPOSE: Epileptic seizure detection has been a complex task for both researchers and specialist in that the assessment of epilepsy is difficult because, electroencephalogram (EEG) signals are chaotic and non-stationary. METHOD: This paper proposes a new method based on weighted visibility graph entropy (WVGE) to identify seizure from EEG signals. Single channel EEG signals are mapped onto the WVGs and WVGEs are calculated from these WVGs. Then some features are extracted of WVGEs and given to classifiers to investigate the performance of these features to classify the brain signals into three groups of normal (healthy), seizure free (interictal) and during a seizure (ictal) groups...
July 11, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28732277/assessment-of-metal-and-pah-profiles-in-suds-soil-based-on-an-improved-experimental-procedure
#17
Damien Tedoldi, Ghassan Chebbo, Daniel Pierlot, Yves Kovacs, Marie-Christine Gromaire
The increasing use of infiltration-based systems for stormwater management questions the soil's ability to act as a long-term filter for runoff contaminants, and brings about operational matters regarding the most effective maintenance practices to enhance contaminant retention in SUDS. This paper reports the vertical extent of metal and PAH contamination in the soil of seven source-control devices in operation for more than 10 years, assessed via a two-step sampling strategy to optimize the representativeness of the contamination profiles...
July 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28732275/plot-farm-and-watershed-scale-effects-of-coffee-cultivation-in-runoff-and-sediment-production-in-western-puerto-rico
#18
Carlos E Ramos-Scharrón, Yasiel Figueroa-Sánchez
The combination of a topographically abrupt wet-tropical setting with the high level of soil exposure that typifies many sun-grown coffee farms represents optimal conditions for high erosion rates. Although traditionally considered as a main cause for water resource degradation, limited empirical evidence has existed to document its true contribution. This study relies on plot-scale experimental results conducted in western Puerto Rico to assess the impact of cultivated surfaces and farm access roads on runoff and sediment production from the plot to the farm and watershed scales...
July 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28732274/new-source-models-to-represent-the-irradiation-process-in-panoramic-gamma-irradiator
#19
Maritza R Gual, Felix M Milian, Amir Z Mesquita, Claubia Pereira
The use of gamma irradiation technologies generates a number of complex scientific and technical problems; for example, the target is manually loaded onto turntables and is rotated during the entire irradiation process and the MCNPX three-dimensional geometry simulation is kept static. For this, it is necessary to introduce additional approaches. In this paper, two new methodologies are proposed for the simulation of irradiation process in panoramic gamma irradiator. The study was performed at the gamma irradiation facility at the Nuclear Technology Development Center of the National Nuclear Energy Commission, Brazil...
June 30, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28732248/effects-of-adults-contingent-responding-on-infants-behavior-in-ambiguous-situations
#20
Gunilla Stenberg
We examined the effect of adults' contingency in responding to infants' behavior in an ambiguous situation in two experiments. In Experiment 1, forty-four 12-month-old infants were exposed to an ambiguous toy. An unfamiliar adult responded either contingently or non-contingently to the infant's bids and then presented the toy and provided positive information. During toy presentation, infants in the non-contingent condition looked less at the experimenter than infants in the contingent condition. In a concluding free-play situation infants in the non-contingent condition played less and tended to touch the toy less...
July 18, 2017: Infant Behavior & Development
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