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https://www.readbyqxmd.com/read/28351067/do-medical-students-narrative-representations-of-the-good-doctor-change-over-time-comparing-humanism-essays-from-a-national-contest-in-1999-and-2013
#1
Pooja C Rutberg, Brandy King, Elizabeth Gaufberg, Pamela Brett-MacLean, Perry Dinardo, Richard M Frankel
PURPOSE: To explore medical students' conceptions of "the good doctor" at two points in time separated by 14 years. METHOD: The authors conducted qualitative analysis of narrative-based essays. Following a constant comparative method, an emergent relational coding scheme was developed which the authors used to characterize 110 essays submitted to the Arnold P. Gold Foundation Humanism in Medicine Essay Contest in 1999 (n = 50) and 2013 (n = 60) in response to the prompt, "Who is the good doctor?" RESULTS: The authors identified five relational themes as guiding the day-to-day work and lives of physicians: doctor-patient, doctor-self, doctor-learner, doctor-colleague, and doctor-system/society/profession...
April 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28351056/comparison-of-umbilical-serum-copeptin-relative-to-erythropoietin-and-s100b-as-asphyxia-biomarkers-at-birth
#2
Milla Summanen, Laura Seikku, Petri Rahkonen, Vedran Stefanovic, Kari Teramo, Sture Andersson, Kai Kaila, Leena Rahkonen
BACKGROUND: Birth asphyxia, estimated to account for a million neonatal deaths annually, can cause a wide variety of neurodevelopmental impairments. There is a need to develop new, swift methods to identify those neonates who would benefit from neuroprotective treatments such as hypothermia. OBJECTIVES: To examine the utility of cord serum copeptin, a stable byproduct of arginine vasopressin release, as a biomarker of birth asphyxia based on a comparison with 2 biomarkers of hypoxia and brain trauma: erythropoietin and S100B...
March 29, 2017: Neonatology
https://www.readbyqxmd.com/read/28350887/auditory-steady-state-responses-and-cochlear-implants-modeling-the-artifact-response-mixture-in-the-perspective-of-denoising
#3
Faten Mina, Virginie Attina, Yvan Duroc, Evelyne Veuillet, Eric Truy, Hung Thai-Van
Auditory steady state responses (ASSRs) in cochlear implant (CI) patients are contaminated by the spread of a continuous CI electrical stimulation artifact. The aim of this work was to model the electrophysiological mixture of the CI artifact and the corresponding evoked potentials on scalp electrodes in order to evaluate the performance of denoising algorithms in eliminating the CI artifact in a controlled environment. The basis of the proposed computational framework is a neural mass model representing the nodes of the auditory pathways...
2017: PloS One
https://www.readbyqxmd.com/read/28350696/monte-carlo-simulations-comparing-the-response-of-a-novel-hemispherical-tepc-to-existing-spherical-and-cylindrical-tepcs-for-neutron-monitoring-and-dosimetry
#4
David P Broughton, Anthony J Waker
Neutron dosimetry in reactor fields is currently mainly conducted with unwieldy flux monitors. Tissue Equivalent Proportional Counters (TEPCs) have been shown to have the potential to improve the accuracy of neutron dosimetry in these fields, and Multi-Element Tissue Equivalent Proportional Counters (METEPCs) could reduce the size of instrumentation required to do so. Complexity of current METEPC designs has inhibited their use beyond research. This work proposes a novel hemispherical counter with a wireless anode ball in place of the traditional anode wire as a possible solution for simplifying manufacturing...
May 2017: Health Physics
https://www.readbyqxmd.com/read/28350673/the-effect-of-workers-compensation-on-outcome-measurement-methods-after-upper-extremity-surgery-a-systematic-review-and-meta-analysis
#5
Yuki Fujihara, Melissa J Shauver, Meghan E Lark, Lin Zhong, Kevin C Chung
BACKGROUND: Patients who receive workers' compensation often display worse surgical results, such as prolonged pain or reduced functional ability. The outcomes of surgery can be assessed using a variety of surveys, assessments, and measurements. It is unknown whether the confounding effect differs based on how results are measured. The aim of this study was to determine whether these variations exist. METHODS: A search of full-length articles published between January 1, 1995, and December 31, 2015, was conducted using 3 online databases...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28350551/the-impact-of-a-violent-physical-assault-on-a-registered-nurse-her-healing-journey-and-return-to-work
#6
Holly Graham
Healthcare practitioners are at an increased risk for workplace violence. What happens to a practitioner after a devastating physical assault from a patient in the workplace? This case report describes the impact of a violent assault on a registered nurse and her healing journey and return to the workplace. The Department of Veteran Affairs/Department of Defense "Clinical Practice Guidelines for Posttraumatic Stress Disorder" outline three categories of risk factors that are associated with the development of posttraumatic stress disorder: pretraumatic factors, peritraumatic or trauma-related factors, and posttraumatic factors...
March 28, 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28350524/an-atf4-atg5-signaling-in-hypothalamic-pomc-neurons-regulates-obesity
#7
Yuzhong Xiao, Yalan Deng, Feixiang Yuan, Tingting Xia, Hao Liu, Zhigang Li, Shanghai Chen, Zhixue Liu, Hao Ying, Yi Liu, Qiwei Zhai, Feifan Guo
ATF4 (activating transcription factor 4) is an important transcription factor that has many biological functions, while its role in hypothalamic POMC (pro-opiomelanocortin-alpha) neurons in the regulation of energy homeostasis has not been explored. We recently discovered that mice with an Atf4 deletion specific to POMC neurons (PAKO mice) are lean and have higher energy expenditure. Furthermore, these mice are resistant to high-fat diet (HFD)-induced obesity and obesity-related metabolic disorders. Mechanistically, we found the expression of ATG5 (autophagy related 5) is upregulated in POMC neurons of PAKO mice, and ATF4 regulates ATG5 expression by binding directly to its promoter...
March 28, 2017: Autophagy
https://www.readbyqxmd.com/read/28350489/redescription-and-molecular-assessment-of-relationships-among-three-species-of-echeneibothrium-rhinebothriidea-echeneibothriidae-parasitizing-the-yellownose-skate-dipturus-chilensis-in-chile
#8
Veronica M Bueno, Janine N Caira
Much progress has recently been made towards revising the taxonomic assignments of genera originally classified in the polyphyletic "Tetraphyllidea". Many of these genera, including Echeneibothrium van Beneden, 1850, were accommodated in the order Rhinebothriidea. However, beyond this larger taxonomic action, little work has been conducted on this genus over the last 50 yrs. As a consequence, the criteria employed for characterizing species of Echeneibothrium have lagged behind those typically employed in more modern descriptions of elasmobranch-hosted cestode taxa...
March 10, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28350475/occupational-radiation-exposure-and-deaths-from-malignant-intracranial-neoplasms-of-the-brain-and-cns-in-u-s-radiologic-technologists-1983-2012
#9
Cari M Kitahara, Martha S Linet, Stephen Balter, Donald L Miller, Preetha Rajaraman, Elizabeth K Cahoon, Raquel Velazquez-Kronen, Steven L Simon, Mark P Little, Michele M Doody, Bruce H Alexander, Dale L Preston
OBJECTIVE: Childhood exposure to acute, high-dose radiation has consistently been associated with risk of benign and malignant intracranial tumors of the brain and CNS, but data on risks of adulthood exposure to protracted, low-to-moderate doses of radiation are limited. In a large cohort of radiologic technologists, we quantified the association between protracted, low-to-moderate doses of radiation and malignant intracranial tumor mortality. MATERIALS AND METHODS: The study population included 83,655 female and 26,642 male U...
March 28, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28350448/mechanism-exploration-of-ion-transport-in-nanocomposite-cation-exchange-membranes
#10
Xin Tong, Bopeng Zhang, Yilin Fan, Yongsheng Chen
The origin of property enhancement of nanocomposite ion exchange membranes (IEMs) is far from being fully understood. By combining experimental work and computational modeling analysis, we could determine the influence of nanomaterials on the ion transport properties of nanocomposite cation exchange membranes (CEMs). We synthesized and characterized a series of nanocomposite CEMs by using SPPO as polymer materials and silica nanoparticles (NPs) (unsulfonated or sulfonated) as nanomaterials. We found that with the increase of NP loading, measured CEM permselectivity and swelling degree first increased and then decreased...
March 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28350431/cellulose-nanofibers-cnf-from-softwood-hardwood-and-tunicate-preparation-structure-film-performance-interrelation
#11
Yadong Zhao, Carl Moser, Mikael E Lindstrom, Gunnar Henriksson, Jiebing Li
This work reveals the structural variations of cellulose nanofibers (CNF) prepared from different cellulose sources, softwood (Picea abies), hardwood (E. grandis x E. urophylla) and tunicate (Ciona intestinalis), using different preparation processes, and their correlations to the formation and performance of the films prepared from the CNF. Here the CNF are prepared from wood chemical pulps and tunicate isolated cellulose by an identical homogenization treatment subsequent to either an enzymatic hydrolysis or a 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO)-mediated oxidation...
March 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28346901/boundary-work-for-implementing-adaptive-management-a-water-sector-application
#12
Blal Adem Esmail, Davide Geneletti, Christian Albert
Boundary work, defined as effort to mediate between knowledge and action, is a promising approach for facilitating knowledge co-production for sustainable development. Here, we investigate a case study of knowledge co-production, to assess the applicability of boundary work as a conceptual framework to support implementing adaptive management in the water sector. We refer to a boundary work classification recently proposed by Clark et al., (2016), based on three types of knowledge uses, i.e. enlightenment, decision-, and negotiation-support, and three types of sources, i...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28346887/high-resolution-mass-spectrometry-as-an-alternative-detection-method-to-tandem-mass-spectrometry-for-the-analysis-of-endogenous-steroids-in-serum
#13
Federico Ponzetto, Julien Boccard, Norbert Baume, Tiia Kuuranne, Serge Rudaz, Martial Saugy, Raul Nicoli
Recently, steroid hormones quantification in blood showed a promising ability to detect testosterone doping and interesting complementarities with the urinary module of the Athlete Biological Passport (ABP). In this work, an ultra-high pressure liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) method was developed for the quantification of eleven endogenous steroids in serum. The performance of the full scan and targeted SIM acquisition modes was evaluated and compared to the performance of tandem mass spectrometry (MS/MS)...
March 18, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28346879/the-spatial-relations-between-stimulus-and-response-determine-an-absolute-visuo-haptic-calibration-in-pantomime-grasping
#14
Shirin Davarpanah Jazi, Matthew Heath
Pantomime-grasps entail a response to an area adjacent to (i.e., spatially dissociated pantomime-grasp), or previously occupied by (i.e., no-target pantomime-grasp) a target. Previous work has reported that pantomime-grasps differ kinematically from naturalistic grasps (i.e., grasping a physical target object) - a result taken to evince that pantomime-grasps are perception-based and mediated via relative visual information. However, such actions differ not only in terms of their visual properties, but also because the former precludes haptic feedback related to a target's absolute size...
March 24, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28346869/multisensory-object-perception-in-infancy-4-month-olds-perceive-a-mistuned-harmonic-as-a-separate-auditory-and-visual-object
#15
Nicholas A Smith, Nicole A Folland, Diana M Martinez, Laurel J Trainor
Infants learn to use auditory and visual information to organize the sensory world into identifiable objects with particular locations. Here we use a behavioural method to examine infants' use of harmonicity cues to auditory object perception in a multisensory context. Sounds emitted by different objects sum in the air and the auditory system must figure out which parts of the complex waveform belong to different sources (auditory objects). One important cue to this source separation is that complex tones with pitch typically contain a fundamental frequency and harmonics at integer multiples of the fundamental...
March 24, 2017: Cognition
https://www.readbyqxmd.com/read/28346840/fabrication-and-evaluation-of-phytomenadione-as-a-nanostructure-lipid-carrier-for-enhancement-of-bioavailability
#16
Bader Mubarak Aljaeid, Khaled Mohamed Hosny
Owing to its limited aqueous solubility, Phytomenadione (vitamin K) undergoes a low bioavailability (50%) with a large inter-individual variability after oral administration. Therefore, the aim of this work was to incorporate vitamine K into nanostructure lipid carrier systems to improve its aqueous solubility and bioavailability. Phytomenadione was used as a liquid lipid, Precirol ATO5, and Compritol ATO were used as solid lipids, Labrasol and Cremophore EL as water soluble surfactants, Capryol 90 and Lauroglycol as lipid soluble surfactants...
March 27, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28346819/parametric-overdispersed-frailty-models-for-current-status-data
#17
Steven Abrams, Marc Aerts, Geert Molenberghs, Niel Hens
Frailty models have a prominent place in survival analysis to model univariate and multivariate time-to-event data, often complicated by the presence of different types of censoring. In recent years, frailty modeling gained popularity in infectious disease epidemiology to quantify unobserved heterogeneity using Type I interval-censored serological data or current status data. In a multivariate setting, frailty models prove useful to assess the association between infection times related to multiple distinct infections acquired by the same individual...
March 27, 2017: Biometrics
https://www.readbyqxmd.com/read/28346817/the-psychosocial-work-environment-is-associated-with-risk-of-stroke-at-working-age
#18
Katarina Jood, Nadine Karlsson, Jennie Medin, Hélène Pessah-Rasmussen, Per Wester, Kerstin Ekberg
Objective The aim of this study was to explore the relation between the risk of first-ever stroke at working age and psychological work environmental factors. Methods A consecutive multicenter matched 1:2 case-control study of acute stroke cases (N=198, age 30-65 years) who had been working full-time at the time of their stroke and 396 sex- and age-matched controls. Stroke cases and controls answered questionnaires on their psychosocial situation during the previous 12 months. The psychosocial work environment was assessed using three different measures: the job-control-demand model, the effort-reward imbalance (ERI) score, and exposures to conflict at work...
March 27, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28346765/the-medial-temporal-memory-system-in-down-syndrome-translating-animal-models-of-hippocampal-compromise
#19
Caron A C Clark, Fabian Fernandez, Stella Sakhon, Goffredina Spanò, Jamie O Edgin
Recent studies have highlighted the dentate gyrus as a region of increased vulnerability in mouse models of Down syndrome (DS). It is unclear to what extent these findings are reflected in the memory profile of people with the condition. We developed a series of novel tasks to probe distinct medial temporal functions in children and young adults with DS, including object, spatial, and serial order memory. Relative to mental age-matched controls (n = 45), individuals with DS (n = 28) were unimpaired on subtests involving short-term object or configural recall that was divorced from spatial or temporal contexts...
March 27, 2017: Hippocampus
https://www.readbyqxmd.com/read/28346759/commentary-what-s-in-a-word-or-words-on-the-relations-among-self-regulation-self-control-executive-functioning-effortful-control-cognitive-control-impulsivity-risk-taking-and-inhibition-for-developmental-psychopathology-reflections-on-nigg-2017
#20
Nancy Eisenberg
In Nigg's excellent article, he deals with a variety of complex conceptual issues related to the constructs of self-regulation and executive functioning (EF). Overall, I agree that the terminology proposed by Nigg should be adopted; moreover, the conceptual distinctions he provides should help the field to move forward with regard to the understanding of varied constructs related to self-regulation. In the spirit of further clarification, I questioned Nigg's suggestions that (a) working memory should be considered as part of the construct of top-down regulation and (b) planning is a higher level component of EF but not part of effortful control...
April 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
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