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https://www.readbyqxmd.com/read/27895871/desmoid-tumor-of-the-chest-wall-mimicking-recurrent-breast-cancer-multimodality-imaging-findings
#1
Kyeong A Choi, Yeong Yi An
Desmoid tumor of breast is a rare benign, locally aggressive tumor with a high recurrence rate. It has been associated with scar from previous breast surgery or trauma. Especially in breast cancer patients with previous operation history, it may simulate recurrent breast cancer clinically and radiologically. We presented multimodality imaging findings (ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography/computed tomography) of chest wall desmoid tumor mimicking recurrent breast cancer in a 38-year-old patient with a history of left modified mastectomy...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27890561/role-of-adjuvant-therapy-for-node-negative-lung-cancer-invading-the-chest-wall
#2
Sarah J Gao, Christopher D Corso, Justin D Blasberg, Frank C Detterbeck, Daniel J Boffa, Roy H Decker, Anthony W Kim
INTRODUCTION: The present study investigated the effect of adjuvant chemotherapy and radiation on survival among patients undergoing chest wall resection for T3N0 non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Patients with T3N0 NSCLC who underwent chest wall resection were identified in the National Cancer Data Base in 2004 to 2012. The cohort was divided into patients who had received adjuvant chemotherapy, radiation therapy, chemoradiation therapy, or no adjuvant treatment...
October 17, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/27872544/breast-lumps-that-do-not-arise-from-the-breast
#3
Srinivas Kodaganur, Priyadarshini C A, Ishwar R Hosamani
An elderly lady presented to the surgical outpatient with a lump in her breast. On examination, there was a well-defined large lump measuring about 12 × 10 cm, hard in consistency and fixed to the chest wall, the skin appeared to be free, and the nipple-areola complex was normal. A provisional diagnosis of phylloides tumor was made, but digital rectal examination revealed a circumferential rectal growth. To our surprise, biopsy of the rectal growth and the chest wall mass revealed similar adenocarcinoma cells...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27871249/benign-clear-cell-sugar-tumor-of-the-lung-in-a-patient-with-birt-hogg-dub%C3%A3-syndrome-a-case-report
#4
Yoko Gunji-Niitsu, Toshio Kumasaka, Shigehiro Kitamura, Yoshito Hoshika, Takuo Hayashi, Hitoshi Tokuda, Riichiro Morita, Etsuko Kobayashi, Keiko Mitani, Mika Kikkawa, Kazuhisa Takahashi, Kuniaki Seyama
BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is a rare inherited autosomal genodermatosis and caused by germline mutation of the folliculin (FLCN) gene, a tumor suppressor gene of which protein product is involved in mechanistic target of rapamycin (mTOR) signaling pathway regulating cell growth and metabolism. Clinical manifestations in BHD syndrome is characterized by fibrofolliculomas of the skin, pulmonary cysts with or without spontaneous pneumothorax, and renal neoplasms. There has been no pulmonary neoplasm reported in BHD syndrome, although the condition is due to deleterious sequence variants in a tumor suppressor gene...
November 21, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27869084/verification-of-dose-distribution-in-carbon-ion-radiation-therapy-for-stage-i-lung-cancer
#5
Daisuke Irie, Jun-Ichi Saitoh, Katsuyuki Shirai, Takanori Abe, Yoshiki Kubota, Makoto Sakai, Shin-Ei Noda, Tatsuya Ohno, Takashi Nakano
PURPOSE: To evaluate robustness of dose distribution of carbon-ion radiation therapy (C-ion RT) in non-small cell lung cancer (NSCLC) and to identify factors affecting the dose distribution by simulated dose distribution. METHODS AND MATERIALS: Eighty irradiation fields for delivery of C-ion RT were analyzed in 20 patients with stage I NSCLC. Computed tomography images were obtained twice before treatment initiation. Simulated dose distribution was reconstructed on computed tomography for confirmation under the same settings as actual treatment with respiratory gating and bony structure matching...
December 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27864598/impact-of-fetal-counseling-on-outcome-of-antenatal-congenital-surgical-anomalies
#6
Shilpa Sharma, Ranjana Bhanot, Dipika Deka, Minu Bajpai, Devendra K Gupta
AIM: To analyze the impact of counseling on antenatal congenital surgical anomalies (ACSA). METHODS: Cases presenting with ACSA for fetal counseling and those presenting in post-natal period following diagnosis of ACSA (PACSA) for surgical opinion were analyzed for spectrum, presentation and outcome. RESULTS: 117 cases including ACSA(68);PACSA(49) were analyzed. Gestational age at diagnosis of ACSA;PACSA was 17-37;17-39 weeks (median 24;32 weeks)...
November 18, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27846900/4dct-and-cbct-based-ptv-margin-in-stereotactic-body-radiotherapy-sbrt-of-non-small-cell-lung-tumor-adhered-to-chest-wall-or-diaphragm
#7
Yi Li, Jing-Lu Ma, Xin Chen, Feng-Wen Tang, Xiao-Zhi Zhang
BACKGROUND: Large tumor motion often leads to larger treatment volumes, especially the lung tumor located in lower lobe and adhered to chest wall or diaphragm. The purpose of this work is to investigate the impacts of planning target volume (PTV) margin on Stereotactic Body Radiotherapy (SBRT) in non-small cell lung cancer (NSCLC). METHODS: Subjects include 20 patients with the lung tumor located in lower lobe and adhered to chest wall or diaphragm who underwent SBRT...
November 15, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27835903/tumor-targeting-salmonella-typhimurium-a1-r-combined-with-temozolomide-regresses-malignant-melanoma-with-a-braf-v600e-mutation-in-a-patient-derived-orthotopic-xenograft-pdox-model
#8
Kei Kawaguchi, Kentaro Igarashi, Takashi Murakami, Bartosz Chmielowski, Tasuku Kiyuna, Ming Zhao, Yong Zhang, Arun Singh, Michiaki Unno, Scott D Nelson, Tara A Russell, Sarah M Dry, Yunfeng Li, Fritz C Eilber, Robert M Hoffman
Melanoma is a recalcitrant disease in need of transformative therapuetics. The present study used a patient-derived orthotopic xenograft (PDOX) nude-mouse model of melanoma with a BRAF-V600E mutation to determine the efficacy of temozolomide (TEM) combined with tumor-targeting Salmonella typhimurium A1-R. A melanoma obtained from the right chest wall of a patient was grown orthotopically in the right chest wall of nude mice to establish a PDOX model. Two weeks after implantation, 40 PDOX nude mice were divided into 4 groups: G1, control without treatment (n = 10); G2, TEM (25 mg/kg, administrated orally daily for 14 consecutive days, n = 10); G3, S...
November 9, 2016: Oncotarget
https://www.readbyqxmd.com/read/27826728/rib-resection-using-a-pneumatic-high-speed-power-drill-system-for-lung-cancer-with-chest-wall-invasion-our-clinical-experience
#9
Yuichiro Ueda, Tatsuo Nakagawa, Toshiya Toyazaki, Naohisa Chiba, Masashi Gotoh
Rib resection for chest wall tumors, including lung cancer with chest wall invasion, is usually performed through open thoracotomy. Resection of part of the external rib cage requires an elongated or additional incision depending on the location and extension of the tumor, eventually becoming more invasive to patients. We recently introduced a technique of rib resection using a pneumatic high-speed power drill system known as "air tome". This novel technique is easy to perform through a small incision or even via video-assisted thoracoscopic surgery (VATS) in selected patients...
November 8, 2016: Surgery Today
https://www.readbyqxmd.com/read/27826375/metastatic-breast-carcinoma-to-the-coronaries-a-rare-cause-of-acute-myocardial-infarction
#10
Nicholas Bhojwani, Alok Harwani, Jason B Hartman, Sasan Partovi, Robert C Gilkeson
A 63-year-old female with a history of invasive ductal breast carcinoma presented to the emergency department with symptoms characteristic of myocardial infarction. Electrocardiography showed sinus tachycardia and ST elevations in leads II, III, and aVF, consistent with inferior wall myocardial infarction. A computed tomography (CT) scan of the chest, abdomen, and pelvis with intravenous contrast demonstrated widespread intrathoracic metastatic disease. Cardiac magnetic resonance imaging (MRI) with contrast revealed obstruction of the left ventricular (LV) outflow tract by an LV mass...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27825689/safety-and-effectiveness-of-cadaveric-allograft-sternochondral-replacement-after-sternectomy-a-new-tool-for-the-reconstruction-of-anterior-chest-wall
#11
Giuseppe Marulli, Andrea Dell'amore, Francesca Calabrese, Marco Schiavon, Niccolò Daddi, Giampiero Dolci, Franco Stella, Federico Rea
BACKGROUND: Surgical excision with wide margins, prevention of respiratory impairment, and protection of surrounding organs are primary goals in resection and reconstruction of the chest wall. We describe our experience of the use of cadaveric cryopreserved sternal allograft. METHODS: Eighteen patients underwent surgery. Indications for sternectomy were sternal metastases (n = 9), primary chondrosarcoma (n = 4), sternal dehiscence (n = 2), soft tissue sarcoma (n = 1), malignant solitary fibrous tumor (n = 1), and direct involvement of thymic carcinoma (n = 1)...
November 5, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27809612/ultrasound-guided-microwave-ablation-a-promising-tool-in-management-of-benign-breast-tumors
#12
Wenbin Zhou, Ruoxi Wang, Xiaoan Liu, Lijun Ling, Mengdi Liang, Cuiying Li, Ge Ma, Li Li, Hong Pan, Haiyan Gong, Qiang Ding, Shui Wang
PURPOSE: Nonsurgical treatments for benign breast tumors have clinical goals of stopping growth and/or reducing (removing) palpable tumors effect without leaving a surgical scar. The purpose of this nonrandomized prospective clinical trial was to assess imaging and clinical outcomes of microwave ablation (MWA) in the treatment of benign breast tumors regardless of the distance from the tumor to the skin and chest wall. METHODS: With approval of the institutional ethics committee and written informed consent, 39 patients with 44 core-biopsy-proved benign breast tumors 3...
November 3, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27807337/-giant-solitary-fibrous-tumor-of-the-pleura-a-case-report-and-literature-review
#13
Guangyan Xu, Jianyong Zhang
Solitary fibrous tumor (SFT) is a derived mesenchymal tumor from spindle cells, mostly occurred in the pleura. To analyze the clinical features of the SFT, data for a patient with SFT that involved in the pleura were retrospectively analyzed by assisted thoracoscope in the Affiliated Hospital of Zunyi Medical College in August 2015. The male patient was 45 years old, who showed the main clinical symptoms of chest pain, cough, sputum, and dyspnea. Large amount of right pleural effusion, chest space-occupying lesions were found by chest CT, suggesting a malignant tumor with metastasis at the 2nd and 3rd right rib...
October 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27785331/congenital-esophageal-duplication-cyst-a-rare-cause-of-dysphagia-in-an-adult
#14
Nikhil Sonthalia, Samit S Jain, Ravindra G Surude, Ashok R Mohite, Pravin M Rathi
Esophageal duplication cyst is a rare congenital embryonal gastrointestinal (GI) malformation which is diagnosed most commonly in childhood. In adults, they can present with a variety of symptoms ranging from dysphagia, chest pain, epigastric discomfort, and vomiting to more serious complications including infections, hemorrhage, and ulcerations. A 30-year-old male presented with gradually progressive dysphagia to solids for 4 months without significant weight loss. Clinical examination and routine laboratory examination were unrevealing...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27785134/surgical-treatment-of-tumours-of-the-sternum-10-years-experience
#15
Katarzyna Kozak, Mariusz P Łochowski, Adam Białas, Michał Rusinek, Józef Kozak
INTRODUCTION: Tumours of the sternum are rare and can be malignant, benign or inflammatory. AIM: To determine the clinical, pathological and therapeutic options for tumours of the sternum. MATERIAL AND METHODS: We report a series of 30 cases of sternal tumours treated in our institution in the period 2006-2015. There were 10 malignant tumours located in the body of the sternum, 2 in the manubrium (metastases of kidney and thyroid carcinoma) and 18 benign tumours located in different parts of the sternum...
September 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27782714/lung-surface-deformation-prediction-from-spirometry-measurement-and-chest-wall-surface-motion
#16
Joubin Nasehi Tehrani, Alistair McEwan, Jing Wang
PURPOSE: The authors have developed and evaluated a method to predict lung surface motion based on spirometry measurements, and chest and abdomen motion at selected locations. METHODS: A patient-specific 3D triangular surface mesh of the lung region was obtained at the end expiratory phase by the threshold-based segmentation method. Lung flow volume changes were recorded with a spirometer for each patient. A total of 192 selected points at a regular spacing of 2 × 2 cm matrix points were used to detect chest wall motion over a total area of 32 × 24 cm covering the chest and abdomen surfaces...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27780619/elastofibroma-dorsi-clinical-evaluation-of-61-cases-and-review-of-the-literature
#17
Mehmet Ali Deveci, Hilmi Serdar Özbarlas, Kıvılcım Eren Erdoğan, Ömer Sunkar Biçer, Mustafa Tekin, Cenk Özkan
OBJECTIVE: Elastofibroma dorsi (ED) is a rare, benign, soft tissue tumor typically located between inferior corner of scapula and posterior chest wall causing mass, scapular snapping, and pain. When classic symptoms and localization are present, it is diagnosed without biopsy and treated with marginal resection. This study retrospectively analyzed patients operated on for ED to evaluate presenting symptoms, tumor size, complications, and clinical results, and to suggest optimal treatments...
October 22, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27778223/mini-review-surgical-management-of-primary-chest-wall-tumors
#18
Takamasa Ito, Hidemi Suzuki, Ichiro Yoshino
Primary chest wall tumors (PCWTs) are relatively rare entities, and their clinical characteristics as well as appropriate treatments are not fully known. Previously reported studies, including ours, are reviewed here, taking into account the clinical approach and findings in Japan for the diagnosis, distribution of histological types, surgical procedures, and prognosis of these entities. Surgery for PCWTs comprised that approximately 0.7 % of surgeries in 2012 in Japan and 28.3 % of PCWTs were malignant with an extremely low rate of mortality within 30 days from surgery...
October 24, 2016: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27777885/male-papillary-breast-cancer-treated-by-wide-resection-and-latissimus-dorsi-flap-reconstruction-a-case-report-and-review-of-the-literature
#19
Malgorzata Banys-Paluchowski, Eike Burandt, Joanna Banys, Stefan Geist, Guido Sauter, Natalia Krawczyk, Peter Paluchowski
Breast cancer (BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation...
October 10, 2016: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27772590/a-glomus-tumor-with-recurrence-and-malignant-transformation-in-the-chest-wall-a-cautionary-tale-of-seeding
#20
Ivan H W Yim, Malcolm B Will, Fiona M Carnochan, William S Walker
Glomus tumors are rare tumors most often occurring in the extremities of the limbs. We report a unique case of a glomus tumor, originally arising in the paraspinal region, which was excised and subsequently recurred in the chest wall with malignant transformation. The recurrence is likely to have been caused by wound seeding. To the best of our knowledge, this is the first report in the English literature of a glomus tumor recurrence secondary to the notion of wound seeding.
November 2016: Annals of Thoracic Surgery
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