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Chest wall tumor

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https://www.readbyqxmd.com/read/29352585/adjuvant-chemotherapy-improves-survival-in-patients-with-completely-resected-t3n0-non-small-cell-lung-cancer-invading-the-chest-wall
#1
Justin A Drake, Jennifer L Sullivan, Benny Weksler
OBJECTIVE: Adjuvant chemotherapy prolongs survival in patients with non-small cell lung cancer with N1 disease or tumors larger than 4 cm. Patients with T3N0 disease due to chest wall invasion often receive adjuvant chemotherapy because their disease is classified as stage II non-small cell lung cancer. This study evaluated whether chemotherapy improves survival after complete resection of T3N0 non-small cell lung cancer with invasion of the chest wall. METHODS: Patients who underwent complete resection of N0 non-small cell lung cancer with invasion of the chest wall were identified in the National Cancer Database...
December 19, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29334989/implantation-of-a-3d-printed-titanium-sternum-in-a-patient-with-a-sternal-tumor
#2
Anton Dzian, Jozef Živčák, Rastislav Penciak, Radovan Hudák
BACKGROUND: Primary malignant or metastatic sternal tumors are uncommon. A subtotal or total sternectomy can offer a radical form of treatment. The issue is to restore the structural integrity of the chest wall. CASE PRESENTATION: We report the implantation of an individualized 3D-printed titanium sternum in a patient with a sternal tumor. CONCLUSIONS: We believe that tridimensional print technologies may also change the strategy of chest wall reconstruction...
January 15, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29324470/fibroma-like-pecoma-a-tuberous-sclerosis-complex-related-lesion
#3
Ana B Larque, Richard L Kradin, Ivan Chebib, G Petur Nielsen, Martin K Selig, Elizabeth A Thiele, Anat Stemmer-Rachamimov, Miriam A Bredella, Pawel Kurzawa, Vikram Deshpande
Perivascular epithelioid cell tumor (PEComa), mesenchymal tumors morphologically characterized by epithelioid cells, coexpress melanocytic and muscle markers. Herein, we describe a heretofore-undescribed tuberous sclerosis complex (TSC)-related neoplasm, morphologically resembling a soft tissue fibroma-like lesion, but showing an immunophenotype resembling PEComa. We identified 3 soft tissue fibroma-like lesions in individuals with TSC. We also evaluated 6 TSC-related periungual fibroma as well as a range of non-TSC fibroma-like lesions (n=19)...
January 10, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29312725/contributing-factors-to-the-outcome-of-primary-malignant-chest-wall-tumors
#4
Abdel Rahman Mohamed Abdel Rahman, Mohamed Rahouma, Rabab Gaafar, Sherif Bahaa, Iman Loay, Mohamed Kamel, Hoda Abdelbaki, Maha Yahia
Background: Primary malignant chest-wall tumors (PMCWTs) are a heterogeneous group of tumors. They require a special experience in designing resection and reconstruction. They account for less than 1% of all primary malignant tumors. This study is designed to clarify different factors contributing to the outcome of patients with PMCWTs in our institution. Methods: A retrospective study included 98 patients with pathology proven PMCWTs, treated at the National Cancer Institute (NCI), Cairo University, Egypt, during the past 10 years...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312715/multidisciplinary-approach-to-chest-wall-resection-and-reconstruction-for-chest-wall-tumors-a-single-center-experience
#5
Elisa Scarnecchia, Valeria Liparulo, Alessandra Pica, Giuseppe Guarro, Carmine Alfano, Francesco Puma
Background: Chest wall resection and reconstruction (CWRR) is quite challenging in surgery, due to evolution in techniques. Neoplasms of the chest wall, primary or secondary, have been considered inoperable for a long time. Thanks to evolving surgical techniques, reconstruction after extensive chest wall resection is possible with good functional and aesthetic results. Methods: In our single-center experience, seven cases of extensive CWRR for tumors were performed with a multidisciplinary approach by both thoracic and plastic surgeons...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29307077/analysis-of-ct-features-and-quantitative-texture-analysis-in-patients-with-thymic-tumors-correlation-with-grading-and-staging
#6
Angelo Iannarelli, Beatrice Sacconi, Francesca Tomei, Marco Anile, Flavia Longo, Mario Bezzi, Alessandro Napoli, Luca Saba, Michele Anzidei, Giulia D'Ovidio, Roberto Scipione, Carlo Catalano
OBJECTIVES: To evaluate potential relationship between qualitative CT features, quantitative texture analysis (QTA), histology, WHO staging, Masaoka classification and myasthenic syndrome in patients with thymic tumors. MATERIALS AND METHODS: Sixteen patients affected by histologically proven thymic tumors were retrospectively included in the study population. Clinical information, with special regard to myasthenic syndrome and serological positivity of anti-AchR antibodies, were recorded...
January 6, 2018: La Radiologia Medica
https://www.readbyqxmd.com/read/29305634/-thoracic-inflammatory-pseudotumors-a%C3%A2-rare-differential-diagnosis
#7
S Sponholz, M Schirren, N Baldes, L Schreiner, A Fisseler-Eckhoff, J Schirren
BACKGROUND: Inflammatory pseudotumors are a rare and in the main benign tumor entity but infiltrative growth, recurrence and metastases are described. Generally, a complete resection is needed to exclude lung cancer. This study analyzed our data and experiences with this rare tumor entity. MATERIAL AND METHODS: We performed a retrospective study of all our patients who had been operated on between 2002 and 2016 in our institution for an inflammatory pseudotumor of the lungs...
January 5, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29304773/breast-carcinoma-with-21-gene-recurrence-score-lower-than-18-rate-of-locoregional-recurrence-in-a-large-series-with-clinical-follow-up
#8
Gulisa Turashvili, Edi Brogi, Monica Morrow, Maura Dickler, Larry Norton, Clifford Hudis, Hannah Y Wen
BACKGROUND: The 21-gene recurrence score (RS) assay determines the benefit of adding chemotherapy to endocrine therapy for patients with early stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. The RS risk groups predict the likelihood of distant recurrence and have recently been associated with an increased risk of locoregional recurrence (LRR). This study analyzed clinicopathologic features of patients with low RS and LRR. METHODS: In our institutional database, we identified 1396 consecutive female patients with lymph node negative, ER+/HER2- invasive breast carcinoma and low RS (<18) results, treated at our center from 2008 to 2013...
January 6, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29260537/diffuse-optical-tomography-using-semiautomated-coregistered-ultrasound-measurements
#9
Atahar Mostafa, Hamed Vavadi, K M Shihab Uddin, Quing Zhu
Diffuse optical tomography (DOT) has demonstrated huge potential in breast cancer diagnosis and treatment monitoring. DOT image reconstruction guided by ultrasound (US) improves the diffused light localization and lesion reconstruction accuracy. However, DOT reconstruction depends on tumor geometry provided by coregistered US. Experienced operators can manually measure these lesion parameters; however, training and measurement time are needed. The wide clinical use of this technique depends on its robustness and faster imaging reconstruction capability...
December 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29251555/reconstruction-of-the-thoracic-wall-with-biologic-mesh-after-resection-for-chest-wall-tumors-a-presentation-of-a-case-series-and-original-technique
#10
Giuseppe D'Amico, Roberto Manfredi, Gabriela Nita, Paola Poletti, Laura Milesi, Luca Livraghi, Eugenio Poletti, Maurizio Verga, Enrico Robotti, Luca Ansaloni
INTRODUCTION: Synthetic materials have traditionally been used for tissue reconstruction in thoracic surgery. New biomaterials have been tested in other areas of surgery with good results. Non-cross-linked swine dermal collagen prosthesis has been used to reconstruct musculofascial defects in the trunk with low infection and herniation rate. MATERIAL AND METHODS: Retrospectively, we analyze our initial experience of chest wall reconstruction on large defects using a non-cross-linked swine dermal collagen matrix mesh with a thickness of 1...
December 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/29240031/thoracic-actinomycosis-with-infiltration-of-the-spine-an-oncological-pitfall
#11
Leila Ronceray, Waltraud Friesenbichler, Caroline Hutter, Karoly Lakatos, Wolfgang Krizmanich, Gabriele Amann, Kaan Boztug, Leo Kager, Georg Mann, Andishe Attarbaschi
Thoracic actinomycosis with involvement of the vertebral column and chest wall is rare in children and may resemble malignant tumors. A 12-year-old girl was admitted to our clinic having B-symptoms, cachexia, and painful scoliosis (Karnofsky index 20%). Imaging showed a large thoracic left-sided paravertebral tumor with infiltration of the vertebrae, destruction of the chest wall and multiple intrapulmonary nodules. Initially, Ewing sarcoma was suspected and chemotherapy started without previous biopsies. Definite diagnosis of actinomycosis was established later upon histopathologic examination and successfully treated by β-lactam antibiotics...
December 12, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29237455/molecular-and-histological-effects-of-mr-guided-pulsed-focused-ultrasound-to-the-rat-heart
#12
Kee W Jang, Tsang-Wei Tu, Matthew E Nagle, Bobbi K Lewis, Scott R Burks, Joseph A Frank
BACKGROUND: Image-guided high intensity focused ultrasound has been used as an extracorporeal cardiac pacing tool and to enhance homing of stem cells to targeted tissues. However, molecular changes in the myocardium after sonication have not been widely investigated. Magnetic-resonance (MR)-guided pulsed focused ultrasound (pFUS) was targeted to the rat myocardium over a range of pressures and the microenvironmental and histological effects were evaluated over time. METHODS: Eight-to-ten-week-old Sprague-Dawley rats received T2-weighted MR images to target pFUS to the left ventricular and septum without cardiac or respiratory gating...
December 13, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29187476/a-case-of-the-resected-lymphohistiocytoid-mesothelioma-bap1-is-a-key-of-accurate-diagnosis
#13
Taichi Matsubara, Gouji Toyokawa, Yuichi Yamada, Kazuki Nabeshima, Naoki Haratake, Yuka Kozuma, Takaki Akamine, Shinkichi Takamori, Fumihiro Shoji, Tatsuro Okamoto, Yoshihiko Maehara
BACKGROUND: Malignant mesothelioma (MM) is a well-known malignant tumor that occurs in the pleura and is histopathologically classified into three subtypes. Lymphohistiocytoid mesothelioma (LHM) is considered a variant of epithelioid MM, and few cases have been reported. First case of LHM was reported by Henderson et al. in 1988. It is difficult to precisely diagnose LHM, and it is often misdiagnosed as reactive mesothelial cell proliferation. CASE REPORT: An 82-year-old man, with the smoking history of nine pack-years, was referred to our Department due to an abnormal shadow and pleural effusion in the left lung field on the chest X-ray imaging...
December 2017: Anticancer Research
https://www.readbyqxmd.com/read/29179900/intra-and-extra-thoracic-muscle-flaps-and-chest-wall-reconstruction-following-resection-of-thoracic-tumors
#14
Sonia L Betancourt Cuellar, Lior Heller, Diana P Palacio, Wayne L Hofstetter, Edith M Marom
Improvements in surgical technique over the last decade enable surgeons to perform extensive resection and reconstruction in patients presenting with tumors involving the soft tissue or bony structures of the chest wall. The type of surgical resection and its size, depend on the type of tumor resected and its location. In addition to providing a better esthetic result, the reconstruction restores support and functionality of the thoracic cage. The approach to chest wall repair includes primary closure or reconstruction by using transposition flaps, free flaps, prosthetic material, or a mixture of a flap and prosthetic material...
December 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29166342/important-considerations-for-performing-prepectoral-breast-reconstruction
#15
REVIEW
Hani Sbitany
Prepectoral breast reconstruction has emerged as an excellent technique for postmastectomy reconstruction, as it allows for full preservation of a patient's pectoralis major muscle and chest wall function. This reduces pain, eliminates animation deformity, and results in high patient satisfaction. Safely performed prepectoral breast reconstruction requires a careful patient selection process before committing to the procedure, taking into account comorbidities, radiation status, and oncologic criteria such as tumor location and breast cancer stage...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29158931/atypical-distant-metastasis-of-breast-malignant-phyllodes-tumors-a-case-report-and-literature-review
#16
Tiphaine de Foucher, Hélène Roussel, Mikael Hivelin, Léa Rossi, Caroline Cornou, Anne-Sophie Bats, Myriam Deloménie, Fabrice Lécuru, Charlotte Ngô
Malignant phyllodes tumors (MPT) are rare breast neoplasms. Preoperative diagnosis is often challenging due to the unspecific clinical, radiological, and histological characteristics of the tumor. Dissemination pathways are local with chest wall invasion, regional with lymph nodes metastasis, and distant, hematogenous, mostly to the lungs, bones, and brain. Distant metastasis (DM) can be synchronous or appear months to years after the diagnosis and initial management. The current report describes the case of a 57-year-old woman presenting with a giant/neglected MPT of the breast, with no DM at initial staging, treated by radical modified mastectomy...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29151797/late-onset-of-primary-pulmonary-primitive-neuroectodermal-tumor-a-case-report
#17
Bilgin Bahadir Başgöz, Adem Aydin, Semra Ince, Ibrahim Demirci, Ayhan Özcan
Lungs are one of most metastatic areas for primitive neuroectodermal tumor (PNET), however primary pulmonary PNET is extremely rare. Here we present a case of a 58-year-old male patient with a tumor in the right lung that originated from the lung but not from chest wall. Patient was diagnosed with PNET following histological and immunohistochemical examination of CT-guided percutaneous tru-cut needle biopsy and no distant metastasis were detected in PET-CT scan. As advised recently in published literature, surgical resection following neoadjuvant chemotherapy protocol is preferred in the treatment of our patient as it has better success of complete resection leading to higher 5-year survival rates...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29132998/waiting-for-radiology-test-results-patient%C3%A2-expectations-and-emotional-disutility
#18
Sean Woolen, Ella A Kazerooni, Amber Wall, Kelly Parent, Shannon Cahalan, Mitchell Alameddine, Matthew S Davenport
PURPOSE: To measure patient willingness to wait and emotional disutility of waiting for outpatient imaging test results. METHODS: A prospective HIPAA-compliant multicenter outpatient quality improvement survey was administered by a trained interviewer to 218 outpatients from November 1, 2016, to February 1, 2017. The survey was vetted by patient- and family-centered care advocates with experience in survey design and underwent precognitive testing for readability...
November 9, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29129340/synchronous-colorectal-cancer-and-multiple-myeloma-with-chest-wall-involvement-is-this-a-coincidence
#19
Qiu-Li Li, Jin-An Ma, Hai-Peng Li, Ren-Bing Huang, Chun-Hong Hu, Xian-Ling Liu, Ya-Wen Gao, Gang-Hua Feng, Fang Wu
Multiple primary malignant neoplasms (MPMNs) are rare malignant neoplasms that simultaneously or successively occur in the same patient as 2 or more primary malignancies. Currently, an increasing number of cases are being reported. In general, MPMNs more commonly occur as 2 solid tumors or 2 hematological malignancies. Cases of MPMN that involve a solid tumor and a hematological malignancy are rare. Here, we report a case of synchronous colorectal cancer (CRC) and multiple myeloma (MM) with chest wall involvement...
September 25, 2017: Current Problems in Cancer
https://www.readbyqxmd.com/read/29106810/stereotactic-body-radiotherapy-for-early-stage-non-small-cell-lung-cancer-american-society-of-clinical-oncology-endorsement-of-the-american-society-for-radiation-oncology-evidence-based-guideline
#20
Bryan J Schneider, Megan E Daly, Erin B Kennedy, Mara B Antonoff, Stephen Broderick, Jill Feldman, Shruti Jolly, Bryan Meyers, Gaetano Rocco, Chad Rusthoven, Ben J Slotman, Daniel H Sterman, Brendon M Stiles
Purpose The American Society for Radiation Oncology (ASTRO) produced an evidence-based guideline on treatment with stereotactic body radiotherapy (SBRT) for patients with early-stage non-small-cell lung cancer. ASCO has a policy and set of procedures for endorsing and/or adapting clinical practice guidelines that have been developed by other professional organizations. Methods The ASTRO Evidence-Based Guideline for Stereotactic Body Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer was reviewed for developmental rigor by methodologists...
November 6, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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