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https://www.readbyqxmd.com/read/29155020/the-uk-dcd-risk-score-a-new-proposal-to-define-futility-in-donation-after-circulatory-death-liver-transplantation
#1
Andrea Schlegel, Marit Kalisvaart, Irene Scalera, Richard W Laing, Hynek Mergental, Darius F Mirza, Thamara Perera, John Isaac, Philipp Dutkowski, Paolo Muiesan
OBJECTIVES: To design a new score on risk assessment in liver transplantation donated after circulatory death (DCD) based on donor and recipient parameters. BACKGROUND: Primary-non-function (PNF) and ischemic cholangiopathy (IC) are the most feared complications following DCD liver transplantation. METHODS: Using the United Kingdom (UK) national DCD database, a risk analysis was performed in adult recipients of DCD liver grafts in UK between 2000 and 2015 (n=1153)...
November 15, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29114517/effects-of-proprioceptive-neuromuscular-facilitation-based-abdominal-muscle-strengthening-training-on-pulmonary-function-pain-and-functional-disability-index-in-chronic-low-back-pain-patients
#2
Beom-Ryong Kim, Hye-Jin Lee
The purpose of this study was to evaluate the effect of abdominal muscle strengthening training (AMST) using proprioceptive neuromuscular facilitation (PNF) on pulmonary function, pain, and functional disability index in chronic low back pain (CLBP) patients. Thirty CLBP patients were randomly assigned to the traditional physical therapy (control) group (n=15) and PNF-AMST group (n=15). Forced expiratory volume at 1 second (FEV1) was measured to measure changes in pulmonary function. To measure the degree of pain, a visual analog scale (VAS) was used...
August 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29114507/investigation-of-alpha-band-of-the-electroencephalogram-before-and-after-a-task-of-proprioceptive-neuromuscular-facilitation
#3
Luan Correia Costa, Alzira Andrade, Lysnara Lial, Rayele Moreira, Ane Caroline Lima, Astrogildo Magvinier, Ricardo Lira, Anderson Aragão, Pedro Henrique Ulisses, Eric Crespo, Marco Orsini, Silmar Teixeira, Victor Hugo Bastos
The proprioceptive neuromuscular facilitation (PNF) sets up a feature of treatment developed with the objective to facilitate and improve the motor performance. The aim of this study was to investigate in healthy female individuals the effects of electrophysiological of a diagonal of the PNF upper limb. The sample consisted of 30 female participants aged between 18 to 28 years, randomly divided into 3 groups (G1, G2, and G3). The three groups had 2 moments of electroencephalographic signal detection, before and after the task...
August 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29098059/curcumin-reverses-the-diazepam-induced-cognitive-impairment-by-modulation-of-oxidative-stress-and-erk-1-2-nf-%C3%AE%C2%BAb-pathway-in-brain
#4
Alexandra C Sevastre-Berghian, Vlad Făgărăsan, Vlad A Toma, Ioana Bâldea, Diana Olteanu, Remus Moldovan, Nicoleta Decea, Gabriela A Filip, Simona V Clichici
Oxidative stress and inflammation can be involved in cognitive dysfunction associated with neurodegenerative disorders. Diazepam (DZP) administration has been chosen to simulate the memory impairment. The aim of this study was to evaluate the effects of curcumin (CUR) on spatial cognition, ambulatory activity, and blood and brain oxidative stress levels. The ERK/NF-κB signaling pathway and the histopathological changes in the hippocampus and frontal lobe, in diazepam-treated rats, were also analyzed. The animals were divided into 4 groups: control, carboxymethylcellulose (CMC) + CUR, CMC + DZP, and CUR + CMC + DZP...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29096587/proprioceptive-neuromuscular-facilitation-increases-alpha-absolute-power-in-the-dorsolateral-prefrontal-cortex-and-superior-parietal-cortex
#5
Lysnara Lial, Rayele Moreira, Luan Correia, Alzira Andrade, Ane Caroline Pereira, Ricardo Lira, Rogério Figueiredo, Fernando Silva-Júnior, Marco Orsini, Pedro Ribeiro, Bruna Velasques, Maurício Cagy, Silmar Teixeira, Victor Hugo Bastos
The physiotherapist's clinical practice includes proprioceptive neuromuscular facilitation (PNF), which is a treatment concept that accelerates the response of neuromuscular mechanisms through spiral and diagonal movements. The adaptations that occur in the nervous system following PNF are still poorly described in the literature. Thus, this study had a goal to investigate the electrophysiological changes in the fronto-parietal circuit during PNF and movement in sagittal and diagonal patterns. This study included 30 female participants, who were divided into three groups (control, PNF, and flexion groups)...
September 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/29084092/acute-effects-of-active-ballistic-passive-and-proprioceptive-neuromuscular-facilitation-streching-on-sprint-and-vertical-jump-performance-in-trained-young-soccer-players
#6
Lucas de Paula Oliveira, Luiz Henrique Palucci Vieira, Rodrigo Aquino, João Paulo Vieira Manechini, Paulo Roberto Pereira Santiago, Enrico Fuini Puggina
The aim of the present study was to compare the acute effects of active (AC), ballistic (BA), passive (PA), proprioceptive neuromuscular facilitation stretching (PNF) methods on performance in vertical jumping, sit and reach, and sprinting in young soccer players. Twelve trained soccer players (17.67 ± 0.87 years) participated in the study. The jump height (H), peak power (PP), and relative power (RP) in the squat jump (SJ) and countermovement jump (CMJ), the range of motion (ROM), the rate of perceived exertion (RPE), and time (s) in 10-20-30 m sprints were evaluated...
October 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29068139/comparative-study-on-chemical-components-and-anti-inflammatory-effects-of-panax-notoginseng-flower-extracted-by-water-and-methanol
#7
Li-Juan Ma, Fang Liu, Zhang-Feng Zhong, Jian-Bo Wan
Methanol and water are commonly used solvents for chemical analysis and traditional decoction, respectively. In the present study, a high-performance liquid chromatography with ultraviolet detection method was developed to quantify 11 saponins in Panax notoginseng Flower extracted by aqueous and methanol solutions, and chemical components and anti-inflammatory effects of these two extracts were compared. The separation of 11 saponins, including notoginsenoside Fc and ginsenoside Rc, was well achieved on a Zorbax SB C18 column...
October 25, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/29040401/a-young-blood-environment-decreases-aging-of-senile-mice-kidneys
#8
Qi Huang, Yichun Ning, Dong Liu, Ying Zhang, Diangeng Li, Yinping Zhang, Zhong Yin, Bo Fu, Guangyan Cai, Xuefeng Sun, Xiangmei Chen
Whether changes in internal body environment affect kidney aging remains unclear. Specifically, it is unknown whether transplanted kidneys from older donors recover from tissue damage after placement in younger recipients. In this study, a parabiosis animal model was established to investigate the effects of a young internal body environment on aged kidneys. The animals were divided into six groups: young (Ycon) and old (Ocon) control groups, isochronic youth-youth group (Y-IP), elderly-elderly group (O-IP) and heterochronic youth (Y-HP) elderly (O-HP) group...
October 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29037625/effects-of-proprioceptive-neuromuscular-facilitation-on-balance-strength-and-mobility-of-an-older-adult-with-chronic-stroke-a-case-report
#9
Christopher S Cayco, Edward James R Gorgon, Rolando T Lazaro
This study described the effects of a proprioceptive neuromuscular facilitation (PNF) program on balance, strength, and mobility in an older adult with chronic stroke. The patient was male, aged 69 years, with right hemiplegia for 17 years, and had diminished balance, balance confidence, lower extremity (LE) strength, and gait velocity. He received 1 h of PNF-based therapy thrice a week for six weeks. Outcome measures were: Mini-BESTest, limits of stability (LOS), Activities-Specific Balance Confidence Scale (ABC), Five Time Sit-to-Stand Test (FTSST), Upright Motor Control Test (UMCT), and 10 Meter Walk Test (10 MWT)...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29034763/pronuclear-pattern-does-not-predict-morphokinetics-behavior-in-human-embryos
#10
Azita Faramarzi, Mohammad Ali Khalili, Marjan Omidi, Azam Agha-Rahimi, Fatemeh Taheri
The purpose was to investigate the correlation between pronuclei (PN) morphology and morphokinetic behaviors of derived embryos with time lapse monitoring (TLM) in assisted reproduction setting. Over time, PN morphology from PN appearance (PNA) to PN fading (PNF), PNF according to size, contact, number and position of nuclear precursor bodies (NPBs) within each PN and morphokinetics variables, including absolute time points, relative timing parameters, cleavage patterns and arrest rate, were evaluated using TLM...
October 16, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29026064/the-effect-of-recipient-body-mass-index-and-its-extremes-on-survival-and-graft-vascular-and-biliary-complications-after-liver-transplantation-a-single-center-retrospective-study
#11
Emmanouil Giorgakis, Michele Tedeschi, Eliano Bonaccorsi-Riani, Shirin Elizabeth Khorsandi, Krishna Menon, Hector Vilca-Melendez, Wayel Jassem, Parthi Srinivasan, Andreas Prachalias, Nigel Heaton
BACKGROUND This is the largest UK-based study on the effect of recipient body mass index (BMI) and its extremes (BMI <18.5 and BMI ≥35 kg/m²) on liver transplant (LT) outcomes. Its purpose was to analyze the BMI effect on post-LT mortality, graft loss, primary non-function (PNF), and graft vascular and biliary complications. MATERIAL AND METHODS Data were retrieved from a single-center LT database of 2,115 consecutive patients receiving first LT during period February 2004 to September 2015. Survivals were compared across the BMI groups; the effects of recipient BMI on survival, PNF, and graft vascular and biliary complications were analyzed via regression...
October 13, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28988441/a-prospective-crossover-trial-of-botulinum-toxin-chemodenervation-versus-injection-augmentation-for-essential-voice-tremor
#12
Christine Estes, Babak Sadoughi, Rachel Coleman, Harini Sarva, Elizabeth Mauer, Lucian Sulica
OBJECTIVES/HYPOTHESIS: Botulinum toxin chemodenervation (BTX) is used to treat essential voice tremor (EVT), but results are not uniformly satisfactory. This study sought to assess the comparative utility of injection augmentation (IA) for EVT. STUDY DESIGN: Prospective crossover treatment study. METHODS: Patients with EVT underwent BTX. After washout patients underwent IA. Multidimensional assessment carried out prior to and 30 days after each treatment included 1) videostroboscopy graded by the Vocal Tremor Scoring System (VTSS), 2) acoustic and aerodynamic assessment (cepstral peak prominence, cepstral spectral index of dysphonia, cepstral peak prominence fundamental frequency, airflow, peak air pressure and intensity, maximum phonation time, and amplitude/frequency of tremor), 3) audio-perceptual assessment via Consensus Audio-Perceptual Evaluation of Voice (CAPE-V), and 4) patient self-assessment via Voice Handicap Index-10 (VHI-10) and Percent of Normal Function (PNF) scale...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28986953/crispr-cas9-mediated-gene-knockout-in-human-coronary-artery-endothelial-cells-reveals-a-pro-inflammatory-role-of-tlr2
#13
Yingge Wang, Zheng Tian, Lu Chen, Xueyi Shen, Xiaohong Wang, Honghai Wu, Yayi Wang, Jiayu Zou, Jingyan Liang
Endothelial inflammatory responses promote the development and progression of atherosclerosis. It was reported that Toll-like receptors 2 (TLR2) is associated with endothelial inflammation. However, the effect of TLR2 on inflammatory responses in human coronary artery endothelial cells (HCAECs) remains largely unknown. Here, we tested the hypothesis that TLR2 can enhance inflammatory reactions in HCAECs after stimulated by TLR2 agonist. First, we used CRISPR-Cas9 technology to knockout TLR2 gene in HCAECs. Then, TLR2-KO and wild type HCAECs were treated with TLR2 agonist peptidoglycan (PGN)...
October 6, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28977681/novel-screening-strategy-reveals-a-potent-bacillus-antagonist-capable-of-mitigating-wheat-take-all-disease-caused-by-gaeumannomyces-graminis-var-tritici
#14
D D Zhang, X J Guo, Y J Wang, T G Gao, B C Zhu
Take-all is a severe root disease of wheat worldwide that is caused by the soilborne fungal pathogen Gaeumannomyces graminis var. tritici (Ggt). In this study, 272 Bacillus isolates were screened for their antifungal activity in vitro to Ggt. Of the 128 strains that demonstrated an antagonistic action, 24 of these exhibited at least three of the four plant-growth-promotion parameters (i.e., indole acetic acid and siderophore production, inorganic phosphorus solubilization and organic phosphorus solubilization) that were tested in wheat plants...
October 4, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28949820/pilates-and-proprioceptive-neuromuscular-facilitation-methods-induce-similar-strength-gains-but-different-neuromuscular-adaptations-in-elderly-women
#15
Fabiana Teixeira de Carvalho, Laiana Sepúlveda de Andrade Mesquita, Rafael Pereira, Osmar Pinto Neto, Renato Amaro Zangaro
Background/Study Context: The aging process is associated with a decline in muscle mass, strength, and conditioning. Two training methods that may be useful to improve muscle function are Pilates and proprioceptive neuromuscular facilitation (PNF). Thus, the present study aimed to compare the influence of training programs using Pilates and PNF methods with elderly women. METHODS: Sixty healthy elderly women were randomly divided into three groups: Pilates group, PNF group, and control group...
September 26, 2017: Experimental Aging Research
https://www.readbyqxmd.com/read/28946541/effects-of-two-proprioceptive-training-programs-on-ankle-range-of-motion-pain-functional-and-balance-performance-in-individuals-with-ankle-sprain
#16
Lazaros Lazarou, Nikolaos Kofotolis, Georgios Pafis, Eleftherios Kellis
BACKGROUND: Following ankle sprain, residual symptoms are often apparent, and proprioceptive training is a treatment approach. Evidence, however, is limited and the optimal program has to be identified. OBJECTIVE: To investigate the effects of two post-acute supervised proprioceptive training programs in individuals with ankle sprain. METHODS: Participants were recruited from a physiotherapy center for ankle sprain rehabilitation. In a pre-post treatment, blinded-assessor design, 22 individuals were randomly allocated to a balance or a proprioceptive neuromuscular facilitation (PNF) group...
September 8, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28946528/pnf-and-manual-therapy-treatment-results-of-patients-with-cervical-spine-osteoarthritis
#17
Tomasz Maicki, Jan Bilski, Elżbieta Szczygieł, Rafał Trąbka
PURPOSE: The aim of this study was to evaluate the effectiveness of PNF and manual therapy methods in the treatment of patients with cervical spine osteoarthritis, especially their efficacy in reducing pain and improving functionality in everyday life. Long-term results were also compared in order to determine which method of treatment is more effective. SUBJECTS AND METHODS: Eighty randomly selected females aged 45-65 were included in the study. They were randomly divided into two groups of 40 persons...
September 22, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28942298/immunohistochemical-expression-profiles-of-cell-adhesion-molecules-matrix-metalloproteinases-and-their-tissue-inhibitors-in-central-and-peripheral-neoplastic-foci-of-feline-mammary-carcinoma
#18
S Pisamai, A Rungsipipat, N Kunnasut, G Suriyaphol
Feline mammary carcinoma (FMC) is a common cancer with high metastatic potential and high mortality rate. Loss of cell-cell interactions and degradation of the extracellular matrix by proteinases enhances tumour invasion and metastasis. Peripheral neoplastic foci (PNF) are defined as the presence of discrete tumour cell clusters, splitting off from central neoplastic foci (CNF) and lodging around these CNF. PNF therefore locate at the tumour-host interface at the site of invasion. The aim of this study was to evaluate immunohistochemically the expression of cell adhesion molecules (e-cadherin [CDH-1], syndecan 1 [SDC-1] and nectin-2), matrix metalloproteinases (matrix metalloproteinase [MMP]-2, MMP-7 and MMP-9) and their tissue inhibitors (tissue inhibitor of matrix metalloproteinase [TIMP]-1 and TIMP-2) together with the cellular proliferation marker, Ki67, in CNF and PNF of FMCs of different clinical stages and histological grades...
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28937253/sirt1-mediates-improvement-in-cognitive-defects-induced-by-focal-cerebral-ischemia-following-hyperbaric-oxygen-preconditioning-in-rats
#19
P Ding, D Ren, S He, M He, G Zhang, Y Chen, H Sang, Z Peng, W Yan
Hyperbaric oxygen preconditioning (HBO-PC) has been proposed as a safe and practical approach for neuroprotection in ischemic stroke. However, it is not known whether HPO-PC can improve cognitive deficits induced by cerebral ischemia, and the mechanistic basis for any beneficial effects remains unclear. We addressed this in the present study using rats subjected to middle cerebral artery occlusion (MCAO) as an ischemic stroke model following HBO-PC. Cognitive function and expression of phosphorylated neurofilament heavy polypeptide (pNF-H) and doublecortin (DCX) in the hippocampus were evaluated 14 days after reperfusion and after short interfering RNA-mediated knockdown of sirtuin1 (Sirt1)...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28917432/complications-after-treating-dupuytren-s-disease-a-systematic-literature-review
#20
C Krefter, M Marks, S Hensler, D B Herren, M Calcagni
The objective of this study was to review the incidence of complications associated with different treatment options for patients with Dupuytren's disease. In a systematic literature review, the PubMed, EMBASE, Cochrane and Scopus databases were searched for clinical studies reporting complications after collagenase treatment, percutaneous needle fasciotomy (PNF), fasciectomy and dermofasciectomy. The incidence of complications was extracted from each study and stratified by procedure. From a total of 2251 references, 113 studies were analyzed and included with complication incidences varying from 0% to 100%...
October 2017: Hand Surgery and Rehabilitation
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