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Ahmer M Hameed, Henry C Pleass, Germaine Wong, Wayne J Hawthorne
BACKGROUND: The two main options for renal allograft preservation are static cold storage (CS) and machine perfusion (MP). There has been considerably increased interest in MP preservation of kidneys, however conflicting evidence regarding its efficacy and associated costs have impacted its scale of clinical uptake. Additionally, there is no clear consensus regarding oxygenation, and hypo- or normothermia, in conjunction with MP, and its mechanisms of action are also debated. The primary aims of this article were to elucidate the benefits of MP preservation with and without oxygenation, and/or under normothermic conditions, when compared with CS prior to deceased donor kidney transplantation...
October 2016: Medicine (Baltimore)
Thanh M Bui, Alain Coron, Jonathan Mamou, Emi Saegusa-Beecroft, Tadashi Yamaguchi, Eugene Yanagihara, Junji Machi, S Lori Bridal, Ernest J Feleppa
OBJECTIVE: To detect metastases in freshly excised human lymph nodes (LNs) using 3-dimensional (3D), high-frequency, quantitative ultrasound (QUS) methods, the LN parenchyma (LNP) must be segmented to preclude QUS analysis of data in regions outside the LNP and to compensate ultrasound attenuation effects due to overlying layers of LNP and residual perinodal fat (PNF). METHODS: After restoring saturated radio-frequency signals from PNF using an approach based on smoothing-cubic splines, the three regions, i...
September 28, 2016: IEEE Transactions on Bio-medical Engineering
Jin-Shei Lai, Sally E Jensen, Zabin S Patel, Robert Listernick, Joel Charrow
Neurofibromatosis Type 1 (NF1) plexiform neurofibromas (pNFs) are associated with a variety of symptoms and concerns that affect patients' quality of life (QOL), highlighting the value of incorporating the patients' perspective when evaluating treatment outcomes. To better conceptualize the experience of patients with pNFs, this qualitative study sought to identify the most important outcomes to assess from the perspective of patients, families, and clinicians. Clinicians, patients age 5 years old and above, and parents of patients aged 5-17 years participated in semi-structured interviews to elicit the pNF symptoms/concerns considered most important to assess...
September 26, 2016: American Journal of Medical Genetics. Part A
Kristian J Hill, Kendall P Robinson, Jennifer W Cuchna, Matthew C Hoch
No abstract text is available yet for this article.
August 24, 2016: Journal of Sport Rehabilitation
Zhiyong Yu, Zhongquan Sun, Songfeng Yu, Lin Zhang, Xiaowen Feng, Mangli Zhang, Xiao Xu, Jian Wu, Jun Yu, Min Zhang, Yan Shen, Weilin Wang, Haiyang Xie, Lin Zhou, Zhenhua Tu, Sheng Yan, Shusen Zheng
BACKGROUND & AIMS: Liver transplantation is the only solution for terminal liver disease. This study aims to determine the association between severity of liver graft steatosis, as well as other risk factors, and poor prognosis of liver transplantation. METHODS: The degree of steatosis was analysed in 563 consecutive liver transplantation and classified by histological examination as M0 (0%), M1 (<30%), M2-1 (30%-39%), M2-2 (40%-49%), M2-3 (50%-59%) or M3 (≥60%)...
September 2, 2016: Liver International: Official Journal of the International Association for the Study of the Liver
Jolanta Krukowska, Marcin Bugajski, Monika Sienkiewicz, Jan Czernicki
In stroke patients, the NDT - (Bobath - Neurodevelopmental Treatment) and PNF (Proprioceptive Neuromuscular Facilitation) methods are used to achieve the main objective of rehabilitation, which aims at the restoration of maximum patient independence in the shortest possible period of time (especially the balance of the body). The aim of the study is to evaluate the effect of the NDT-Bobath and PNF methods on the field support and total path length measure foot pressure (COP) in patients after stroke. The study included 72 patients aged from 20 to 69 years after ischemic stroke with Hemiparesis...
August 20, 2016: Neurologia i Neurochirurgia Polska
Agnieszka Wolińska, Agnieszka Kuźniar, Urszula Zielenkiewicz, Artur Banach, Dariusz Izak, Zofia Stępniewska, Mieczysław Błaszczyk
The main goal of the study was to determine the diversity of the potential nitrogen-fixing (PNF) bacteria inhabiting agricultural (A) soils versus wastelands serving as controls (C). The soils were classified into three groups based on the formation process: autogenic soils (Albic Luvisols, Brunic Arenosols, Haplic Phaeozem) formed on loess material, hydrogenic soils (Mollic Gleysols, Eutric Fluvisol, Eutric Histosol) formed under the effect of stagnant water and lithogenic soils (Rendzina Leptosols) formed on limestone...
August 31, 2016: Microbial Ecology
Somak Das, Sudeepta Kumar Swain, Pavan Kumar Addala, Ramakrishnan Balasubramaniam, C V Gopakumar, Dinesh Zirpe, Kirubakaran Renganathan, Harsha Kollu, Darshan Patel, Bipin B Vibhute, Prashantha S Rao, Elankumaran Krishnan, Mahesh Gopasetty, Anand K Khakhar, Anil Vaidya, Anand Ramamurthy
BACKGROUND: Nations with emerging deceased-donor liver transplantation programs, such as India, face problems associated with poor donor maintenance. Cold ischemic time (CIT) is typically maintained short by matching donor organ recovery and recipient hepatectomy to achieve maximum favorable outcome. We analyzed different extended criteria donor factors including donor acidosis, which may act as a surrogate marker of poor donor maintenance, to quantify the risk of primary nonfunction (PNF) or initial poor function (IPF)...
August 19, 2016: Progress in Transplantation
Xiaojie Hu, Melia Bogari, Andy Tan, Xiaoyan Gao, Yang Gao, Hui Chen, Wei Li, Yunbo Jin, Gang Ma, Xiaoxi Lin
BACKGROUND: Large temporal plexiform neurofibroma (PNF) is an irritating problem that causes facial disfigurement. Surgical resection of PNF is the only effective way to remove the tumor as well as to improve the patient's facial appearance. However, temporal branch of the facial nerve (TBFN) in the tumor is prone to be destroyed during PNF removal. Thus, TBFN palsy is the inevitable complication after surgery and might induce other malformation and dysfunction. Therefore, the aim of this study is to reconstruct a nearly normal face contour while preserving the facial nerve function...
September 2016: Journal of Craniofacial Surgery
Claire Pellot-Barakat, Linda Chami, Jean Michel Correas, Muriel Lefort, Olivier Lucidarme
This study was undertaken to evaluate the impact of free-breathing (FB) vs. Apnea on Shear-wave elastography (SWE) measurements. Quantitative liver-stiffness measurements were obtained during FB and Apnea for 97 patients with various body-morphologies and liver textures. Quality indexes of FB and Apnea elasticity maps (percentage of non-filling (PNF), temporal (TV) and spatial (SV) variabilities) were computed. SWE measurements were also obtained from an homogeneous phantom at rest and during a mechanically-induced motion...
September 2016: European Journal of Radiology
Justin F Hummer, Gerald C Davison
BACKGROUND: Personalized normative feedback (PNF) interventions are designed to reduce misperceived drinking norms by delivering feedback regarding the actual drinking behavior of college students, thereby leading to subsequent reductions in one's own drinking. OBJECTIVE: We examined the roles of data source credibility and reference group proximity in the effectiveness of a laboratory-based PNF intervention to reduce perceived drinking norms and thereby decrease intentions to drink...
November 9, 2016: Substance Use & Misuse
Xiaoli Fan, Zhiquan Chen, David Nasralla, Xianpeng Zeng, Jing Yang, Shaojun Ye, Yi Zhang, Guizhu Peng, Yanfeng Wang, Qifa Ye
Between 2010 and 2013, we recorded 66 cases of failed organ donation after brain death (DBD) due to the excessive use of the vasoactive drugs resulting in impaired hepatic and/or renal function. To investigate the effect of extracorporeal membrane oxygenation (ECMO) in donor management, ECMO was used to provide support for DBD donors with circulatory and/or respiratory failure from 2013 to 2015. A retrospective cohort study between circulatory non-stable DBD with vasoactive drugs (DBD-drug) and circulatory non-stable DBD with ECMO (DBD-ECMO) was designed to compare the transplant outcomes...
October 2016: Clinical Transplantation
Huifeng Liu, Guohua Liu, Ya Li, Xing Wu, Dan Liu, Xiaoqin Dai, Ming Xu, Fengting Yang
Land use conversion and fertilization have been widely reported to be important managements affecting the exchanges of greenhouse gases between soil and atmosphere. For comprehensive assessment of methane (CH4) and nitrous oxide (N2O) fluxes from hilly red soil induced by land use conversion and fertilization, a 14-month continuous field measurement was conducted on the newly converted citrus orchard plots with fertilization (OF) and without fertilization (ONF) and the conventional paddy plots with fertilization (PF) and without fertilization (PNF)...
July 22, 2016: Environmental Science and Pollution Research International
Utku Alemdaroglu, Yusuf Köklü, Mitat Koz
BACKGROUND: The purpose of this study was to compare the acute effects of different stretching types on sprint performance in taekwondo practitioners. METHODS: Twelve male taekwondo practitioners performed stretching exercises using different types (ballistic, proprioceptive neuromuscular facilitation (PNF), static stretching) in a random order at three-day intervals; there was also a control condition involving no stretching exercises. The subjects performed 2 maximal 20m sprints (with 10m split times also recorded) with a recovery period of 1 minute immediately post stretching and at 5, 10, 15 and 20 minutes after stretching...
July 21, 2016: Journal of Sports Medicine and Physical Fitness
Simona Clichici, Diana Olteanu, Adriana Filip, Andras-Laszlo Nagy, Adrian Oros, Petru A Mircea
Silymarin (Si) is a herbal product with hepatoprotective potential, well-known for its antioxidant, anti-inflammatory, and immunomodulatory properties. We have recently demonstrated that the usual therapeutic doses of Si are capable of inhibiting the progression of incipient liver fibrosis. We aimed at further investigating the benefits of Si administration upon liver alterations after the hepatotoxin discontinuation, using CCl4 to induce liver injuries on rats. CCl4 administration induces first of all oxidative stress, but other mechanisms, such as inflammation and liver fibrosis are also triggered...
August 2016: Journal of Medicinal Food
R Liang, Z Wang, M N Zhu, C X Hao, N Zhang, J H Wang, T Zhang, L Yang, H T Gu, B X Dong, Q X Bai, G X Gao, X Q Chen
OBJECTIVE: To investigate the clinical characteristics and prognostic factors of mantle cell lymphoma (MCL) patients. METHODS: The clinical data of 23 MCL patients were retrospectively analyzed. Immunohistochemical stain was performed to detect the protein expressions of Mcl-1, pNF-κB p65 and 14-3-3ζ of MCL patients to analyze its prognostic factors. RESULTS: Among 23 MCL patients, there were 17(73.9%) patients with IPI 0-2 (low risk group) and 6(26...
June 14, 2016: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
C Boffa, F van de Leemkolk, E Curnow, J Homan van der Heide, J Gilbert, E Sharples, R J Ploeg
The gap between supply and demand in kidney transplantation has led to increased use of marginal kidneys; however, kidneys with acute kidney injury are often declined/discarded. To determine whether this policy is justified, we analyzed outcomes of donor kidneys with acute kidney injury (AKI) in a large UK cohort. A retrospective analysis of the UK Transplant Registry evaluated deceased donors between 2003 and 2013. Donors were classified as no AKI, or AKI stage 1-3 according to Acute Kidney Injury Network (AKIN) criteria...
July 18, 2016: American Journal of Transplantation
Siyuan Li, Yuting Ren, Wenjia Zhu, Fei Yang, Xiaolan Zhang, Xusheng Huang
BACKGROUND AND OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by degeneration of both upper and lower motor neurons. In this study, we aimed to measure both plasma and cerebrospinal fluid (CSF) phosphorylated neurofilament heavy chain (pNF-H) levels in patients with ALS, and determine if there is a correlation. We also evaluated plasma and CSF pNF-H levels to investigate if this biomarker could predict the time to generalization (TTG) in ALS better. METHODS: Paired plasma and CSF pNF-H levels of patients with ALS (n=51), multiple system atrophy (n=12) and controls (n=30) were measured by monoclonal sandwich ELISA...
August 15, 2016: Journal of the Neurological Sciences
Jwa-Jun Kim, Se-Yeon Park
[Purpose] The purpose of this study was to evaluate the immediate effect of stabilizing exercise using the PNF technique on standing balance in one-leg and double-leg stances. [Subjects and Methods] The present study recruited 34 healthy participants from a local university. The Participants performed four balance tests (double-leg stance with and without vision, one-leg stance with and without vision), before and after exercise. The exercise consisted of exercises performed using PNF techniques (stabilizing reversal and rhythmic stabilization), which were applied to facilitate trunk musculature...
June 2016: Journal of Physical Therapy Science
A Konrad, S Stafilidis, M Tilp
The purpose of this study was to investigate the influence of a single static, ballistic, or proprioceptive neuromuscular facilitation (PNF) stretching exercise on the various muscle-tendon parameters of the lower leg and to detect possible differences in the effects between the methods. Volunteers (n = 122) were randomly divided into static, ballistic, and PNF stretching groups and a control group. Before and after the 4 × 30 s stretching intervention, we determined the maximum dorsiflexion range of motion (RoM) with the corresponding fascicle length and pennation angle of the gastrocnemius medialis...
July 1, 2016: Scandinavian Journal of Medicine & Science in Sports
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