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https://www.readbyqxmd.com/read/29228442/a-novel-boswellic-acids-delivery-form-casperome%C3%A2-in-the-management-of-musculoskeletal-disorders-a-review
#1
A Riva, P Allegrini, F Franceschi, S Togni, L Giacomelli, R Eggenhoffner
Standard pharmacological treatment of musculoskeletal conditions is often associated with relevant side effects. Botanical preparations endowed with a good tolerability profile, therefore, could have a role in the management of these disorders. Among different natural products, Boswellia serrata extracts have long been used for the treatment of musculoskeletal disorders, given their marked anti-inflammatory activity and their ability to promote tissue regeneration. However, standard preparations of Boswellia serrata show overall modest pharmacokinetic properties, a limitation which may ultimately lead to reduced efficacy...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29227572/factors-associated-with-serum-magnesium-and-vascular-stiffness-in-maintenance-hemodialysis-patients
#2
Mai Yorifuji, Takahiro Kuragano, Sayuri Kawada, Wataru Fukao, Kazuhiro Toyoda, Takeshi Nakanishi
INTRODUCTION: We evaluated the associated factors of serum magnesium in patients on maintenance hemodialysis (MHD). Furthermore, we evaluated the relationship between low serum magnesium and arteriosclerosis in these patients. METHODS: In 129 patients on MHD, we evaluated the blood levels of magnesium, brachial-ankle pulse wave velocity (ba-PWV), ankle-brachial index (ABI), and intima-media thickness of the common carotid artery (IMT). FINDINGS: In MHD patients, the serum level of magnesium was significantly correlated with age, calcium, TNF-α, albumin, and ba-PWV but not with ABI or IMT...
December 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29227525/functional-electrical-stimulation-and-ankle-foot-orthoses-provide-equivalent-therapeutic-effects-on-foot-drop-a-meta-analysis-providing-direction-for-future-research
#3
Sarah Prenton, Kristen L Hollands, Laurence P J Kenney, Pornsuree Onmanee
OBJECTIVE: To compare the randomized controlled trial evidence for therapeutic effects on walking of functional electrical stimulation and ankle foot orthoses for foot drop caused by central nervous system conditions. DATA SOURCES: MEDLINE, CINAHL, Cochrane Central Register of Controlled Trials, REHABDATA, PEDro, NIHR Centre for Reviews and Dissemination, Scopus and clinicaltrials.gov. STUDY SELECTION: One reviewer screened titles/abstracts...
November 17, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29226198/restoration-of-the-mechanical-axis-in-total-knee-artrhoplasty-using-patient-matched-technology-cutting-blocks-a-retrospective-study-of-132-cases
#4
Dimitrios N Lyras, Robert Greenhow, Craig Loucks
Background: The aim of this study is to evaluate the accuracy of bone cuts and the resultant alignment, using the MyKnee patient specific cutting blocks. Methods: We retrospectively reviewed 132 patients undergoing primary TKR for osteoarthritis by one single surgeon. The operative time, the preoperative Hip-Knee-Ankle (HKA) axis based on the CT-scan, the postoperative HKA axis based on long axis standing x-rays, the planned and the actual size of the femoral and the tibial components, and the number of the recuts which has been made intraoperative were measured...
September 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29225591/incidence-of-peripheral-arterial-disease-and-its-association-with-pulse-pressure-a-prospective-cohort-study
#5
Yong Mao, Yixiang Huang, Haining Yu, Peng Xu, Guangping Yu, Jinming Yu, Yiqiang Zhan
Background: The association of pulse pressure and peripheral arterial disease (PAD) has seldom been examined using a prospective design. This study aimed to investigate the association of pulse pressure with PAD incidence in an elderly general population. Methods: We utilized data from a cohort conducted in Beijing with additionally 2-year follow-up time. PAD was defined as an ankle brachial index value <0.9 in either leg. Cox proportional hazard regression model was used to quantify the magnitude of pulse pressure on PAD incidence...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29224948/a-modified-foot-and-ankle-score-for-assessing-patient-outcomes-after-first-metatarsophalangeal-arthrodesis
#6
Hao Guo, Hai-Lin Xu, Hao Lu, Bao-Guo Jiang
First metatarsophalangeal (MTP) arthrodesis is commonly used to treat many end-stage first MTP diseases. The most widely used scale for measuring the clinical outcomes after this procedure, the American Orthopaedic Foot and Ankle Society Hallux Metatarsophalangeal-Interphalangeal scale, has not been adequately validated and does not measure specific foot functions. Another outcome measure, the patient-reported Foot and Ankle Outcome Score (FAOS) has acceptable construct validity but poor content validity. The FAOS scale has 42 questions, many of which are unrelated to the hallux...
December 7, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29224940/results-of-nonoperative-management-of-acute-limb-ischemia-in-infants
#7
S Keisin Wang, Gary W Lemmon, Natalie A Drucker, Raghu L Motaganahalli, Michael C Dalsing, Ashley R Gutwein, Brian W Gray, Michael P Murphy
OBJECTIVE: Acute limb ischemia (ALI) in infants poses a challenge to the clinician secondary to poor operative outcomes, limb loss risk, and lifelong morbidity. This retrospective study reviewed a 10-year institutional experience with the nonoperative management of ALI in infants. METHODS: Infants (aged ≤12 months) diagnosed with ALI by duplex ultrasound and treated with initial nonoperative management at a tertiary care children's hospital were identified through vascular laboratory arterial duplex ultrasound records and International Classification of Diseases and Current Procedural Terminology codes associated with ALI...
December 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29224907/quantitative-postural-analysis-of-children-with-congenital-visual-impairment
#8
Michelle de Pádua, Juliana F Sauer, Silvia M A João
OBJECTIVES: The aim of this study was to compare the postural alignment of children with visual impairment with that of children without visual impairment. METHODS: The sample studied was 74 children of both sexes ages 5 to 12 years. Of these, 34 had visual impairment and 40 were control children. Digital photos from the standing position were used to analyze posture. Postural variables, such as tilt of the head, shoulder position, scapula position, lateral deviation of the spine, ankle position in the frontal plane and head posture, angle of thoracic kyphosis, angle of lumbar lordosis, pelvis position, and knee position in the frontal and sagittal planes, were measured with the Postural Assessment Software 0...
December 7, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29224233/review-article-methodology-for-the-rapid-review-series-on-musculoskeletal-injuries-in-the-emergency-department
#9
REVIEW
Kirsten Strudwick, Megan McPhee, Anthony Bell, Melinda Martin-Khan, Trevor Russell
Musculoskeletal injuries are a common presentation to the ED, with significant costs involved in the management of these injuries, variances in care within the ED and associated morbidity. A series of rapid review papers were completed to guide best practice for the assessment and management of common musculoskeletal injuries presenting to the ED. This paper presents the methodology used across the rapid reviews. PubMed, CINAHL, EMBASE, TRIP and the grey literature, including relevant organisational websites, were searched in 2015...
December 10, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29224059/lower-complication-rate-and-faster-return-to-sports-in-patients-with-acute-syndesmotic-rupture-treated-with-a-new-knotless-suture-button-device
#10
Christian Colcuc, Marc Blank, Thomas Stein, Florian Raimann, Sanjay Weber-Spickschen, Sebastian Fischer, Reinhard Hoffmann
PURPOSE: Suture button devices for tibiofibular syndesmosis injuries provide semirigid dynamic stabilization, but complications including knot irritation have been reported. No randomized trials of the new knotless suture button devices have been performed. We hypothesized that knotless suture button devices eliminate knot irritation and facilitate quicker return to sports. This study was performed to compare the clinical outcomes, complication rates, and time to return to sports between a new knotless suture button device and syndesmotic screw fixation...
December 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29223884/chronic-effect-of-different-types-of-stretching-on-ankle-dorsiflexion-range-of-motion-systematic-review-and-meta-analysis
#11
REVIEW
Diulian Muniz Medeiros, Tamara Fenner Martini
The calf muscles are one of the muscle groups that have the most need for adequate flexibility since they are deeply related to normal lower limb function. When the goal is to increase flexibility, the most commonly used technique is stretching. However, it remains unknown which stretching technique and parameters are the most effective to increase flexibility. Hence, the aim of the current review was to investigate the influence of chronic stretching on ankle dorsiflexion range of motion (DFROM) of healthy individuals...
October 27, 2017: Foot
https://www.readbyqxmd.com/read/29221901/role-of-heel-lifting-in-standing-balance-recovery-a-simulation-study
#12
Kuangyou B Cheng, Hiroko Tanabe, Wen-Chien Chen, Hung-Ta Chiu
Although lifting the heels has frequently been observed during balance recovery, the function of this movement has generally been overlooked. The present study aimed to investigate the functional role of heel lifting during regaining balance from a perturbed state. Computer simulation was employed to objectively examine the effect of allowing/constraining heel lifting on balance performance. The human model consisted of 3 rigid body segments connected by frictionless joints. Movements were driven by joint torques depending on current joint angle, angular velocity, and activation level...
December 2, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29221678/hybrid-imaging-in-foot-and-ankle-disorders
#13
R García Jiménez, F J García-Gómez, E Noriega Álvarez, C Calvo Morón, J J Martín-Marcuartu
Disorders of the foot and ankle are some of the most frequent ones affecting the musculoskeletal system and have a great impact on patients' quality of life. Accurate diagnosis is an important clinical challenge because of the complex anatomy and function of the foot, that make it difficult to locate the source of the pain by routine clinical examination. In the study of foot pathology, anatomical imaging (radiography, magnetic resonance imaging [MRI], ultrasound and computed tomography [CT]) and functional imaging (bone scan, positron emission tomography [PET] and MRI) techniques have been used...
December 5, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29220619/the-effect-of-whole-body-vibration-on-lower-body-resistance-detraining-in-college-age-women
#14
Keston G Lindsay, David L Nichols, Ronald W Davis, David D Marshall
PURPOSE: This study explored the effect of whole-body vibration (WBV) using accelerations of 2.56 g to 7.68 g on lower-body detraining. METHODS: All participants (N = 20) were trained using a lower-body resistance-training program for 30 min twice per week from Week 0 to Week 6. At the end of the program, they were randomly assigned to a control group that performed no further training or a WBV group that performed a progressive static WBV program. Data for the 5-repetition-maximum (5RM) squat and extensors and flexors of the knee and ankle were collected at Weeks 0, 6, 8, 10, and 12 for all participants...
December 8, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29220324/performance-of-optimized-prosthetic-ankle-designs-that-are-based-on-a-hydraulic-variable-displacement-actuator-vda
#15
James Gardiner, Abu Zeeshan Bari, Laurence Kenney, Martin Twiste, David Moser, Saeed Zahedi, David Howard
Current energy storage and return prosthetic feet only marginally reduce the cost of amputee locomotion compared with basic solid ankle cushioned heel feet, possibly due to their lack of push-off at the end of stance. To the best of our knowledge, a prosthetic ankle that utilizes a hydraulic variable displacement actuator (VDA) to improve push-off performance has not previously been proposed. Therefore, here we report a design optimization and simulation feasibility study for a VDA-based prosthetic ankle. The proposed device stores the eccentric ankle work done from heel strike to maximum dorsiflexion in a hydraulic accumulator and then returns the stored energy to power push-off...
December 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29219020/correlation-of-mri-appearance-of-autologous-chondrocyte-implantation-in-the-ankle-with-clinical-outcome
#16
Keith W Chan, Richard D Ferkel, Brian Kern, Sarah S Chan, Gregory R Applegate
The objective of this study was to characterize magnetic resonance imaging (MRI) findings and correlate with clinical results in patients who underwent autologous chondrocyte implantation (ACI) of osteochondral lesions of the talus (OLT). METHODS: Twenty-four grafts were evaluated at a mean 65.8 months after ACI for OLT. MRI was performed on a 1.5-T GE scanner using multiple sequences. Graft appearance was compared with preoperative MRI and evaluated for 6 criteria: defect fill, surface regularity, signal pattern, bone marrow edema, subchondral plate irregularity, and presence of cystic lesions...
January 2018: Cartilage
https://www.readbyqxmd.com/read/29218759/impact-of-pain-and-functional-impairment-in-us-adults-with-haemophilia-patient-reported-outcomes-and-musculoskeletal-evaluation-in-the-pain-functional-impairment-and-quality-of-life-p-fiq-study
#17
C L Kempton, M Recht, A Neff, M Wang, T W Buckner, A Soni, D Quon, M Witkop, L Boggio, R Z Gut, D L Cooper
INTRODUCTION: Standardized and disease-specific patient-reported outcome (PRO) instruments assessing pain, functional impairment and health-related quality of life (HRQoL) in people with haemophilia (PWH) have been used in studies, but infrequently in comprehensive care settings for individual assessment or treatment planning. AIM: To assess the impact of pain and functional impairment on HRQoL in PWH. METHODS: P-FiQ enrolled 381 adult PWH with a history of joint pain/bleeding and included 5 PROs and a clinical joint evaluation (Hemophilia Joint Health Score v2...
December 8, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29218618/metal-artifact-reduction-mri-of-total-ankle-arthroplasty-implants
#18
Cesar de Cesar Netto, Lucas F Fonseca, Benjamin Fritz, Steven E Stern, Esther Raithel, Mathias Nittka, Lew C Schon, Jan Fritz
OBJECTIVES: To assess high-bandwidth and compressed sensing-(CS)-SEMAC turbo spin echo (TSE) techniques for metal artifact reduction MRI of total ankle arthroplasty (TAA) implants. METHODS: Following institutional approval and consent, 40 subjects with TAA implants underwent 1.5-T MRI prospectively. Evaluations included bone-implant interfaces, anatomical structures, abnormal findings and differential diagnoses before and after MRI. AUCs of P-P plots were used to determine superiority...
December 7, 2017: European Radiology
https://www.readbyqxmd.com/read/29218309/kinematic-changes-during-prolonged-fast-walking-in-old-and-young-adults
#19
Camila Fonseca Oliveira, Edgar Ramos Vieira, Filipa Manuel Machado Sousa, João Paulo Vilas-Boas
Walking biomechanics is known to be influenced by speed. However, most of the research examining the effects of walking speed and gait characteristics has been conducted after a fast-walking task, neglecting the changes that may occur during the task. The aim of the present study was to determine the impact of fast-walking over time on kinematics in young and old adults. Twenty-seven young adults (26.6 ± 6.0 years) and 23 old adults (71.0 ± 5.6 years) walked at 70% of their maximum heart rate for 20 min or until exhaustion, and the effects of fast-walking on temporospatial parameters and on angular kinematics were analyzed during the activity...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29217947/coexistence-of-peripheral-spondyloarthritis-and-familial-adenomatous-polyposis-a-rare-case-report-with-treatment-contradictions-and-review-of-the-literature
#20
Berna Urkmez, Muge Kepekci, Sevde Ozer Posul, Aylin Rezvani
Background: The coexistence of familial adenomatous polyposis and spondyloarthritis is rarely defined in literature. The primary aim of this presentation is to report a development of peripheral arthritis in 3 years following colon surgery with the diagnosis of familial adenomatous polyposis (FAP). The secondary aim is to discuss the challenge of in treatment of refractory arthritis, which needs to be treated with biologics. However, it is not yet known well about their safety on patients who have risks for cancer development...
July 2017: Ethiopian Journal of Health Sciences
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