keyword
https://read.qxmd.com/read/38531794/creation-of-an-atherosclerosis-model-using-palmitic-acid-and-oleic-acid-in-the-vascular-smooth-muscle-cells-of-rats
#21
JOURNAL ARTICLE
Fan Zhang, Guangping Li, Xueyin Li, Yi Zheng, Wanting Du, Bo Zhao, Da Sun
BACKGROUND: Atherosclerosis (AS) is a chronic vascular inflammatory disease resulting from vascular endothelial injury and lipid deposition, closely linked to abnormal lipid metabolism within the body. The critical processes involved in atherosclerosis encompass lipid deposition, oxidation, metabolic disruptions, and inflammatory stimulation within the inner vessel wall. Lipid deposition emerges as a pivotal factor triggering these pathological changes, with vascular smooth muscle cells (VSMCs) playing a significant role in the development of AS...
March 2024: Discovery Medicine
https://read.qxmd.com/read/38531344/treating-lateral-epicondylopathy-with-dry-needling-and-exercise-a-case-series
#22
JOURNAL ARTICLE
Brian V Hortz, Sue Falsone
CONTEXT: Lateral epicondylopathy (LE) is a common overuse injury affecting elbow, wrist, and hand function. It is characterized by weakness and pain in the muscles and tendons of the forearm responsible for the extension of your wrist and fingers. Trigger point dry needling is a technique reported to be beneficial in managing pain and dysfunction after LE diagnosis. LE is also commonly treated with conservative treatment, such as joint and soft tissue mobilization, self-care home programs, and anti-inflammatory use...
March 26, 2024: Journal of Sport Rehabilitation
https://read.qxmd.com/read/38530383/the-accessory-vascularization-of-the-tensor-fasciae-latae-muscle-towards-a-new-classification
#23
JOURNAL ARTICLE
Silvia Gandolfi, B Chaput, Y Berkane, E Lupon, A Karra
PURPOSE: The tensor fasciae latae (TFL) muscle is supplied by the lateral femoral circumflex artery (LCFA), arising from the deep femoral artery. However, it has been noted that there is also a consistent vascular anastomotic network. The aim of this study was to describe the accessory vascularization of the TFL muscle through a descriptive anatomical study, in order to hypothesize the feasibility of harvesting a TFL flap in the event of an injury to the main pedicle. In addition, we illustrate this hypothesis with a successful clinical case of Scarpa freconstruction following ligature of the deep femoral artery...
March 26, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38529764/gender-specific-hip-strength-disparities-correlate-with-injury-patterns-in-ncaa-men-s-and-women-s-soccer-players
#24
JOURNAL ARTICLE
David R Bakal, Farah S Hussain, Justin T Dzierzawski, Daniel T Meyer, Holli E Dawson, Oluseun A Olufade
BACKGROUND: In National Collegiate Athletic Association (NCAA) soccer athletes, men have higher rates of hip and groin strains, whereas women have higher rates of knee ligament injuries. Strength imbalances of the hip and thigh, specifically in agonist-antagonist muscles, are known risk factors for these injuries. OBJECTIVE: To perform hip and thigh strength assessments in NCAA soccer players to evaluate for differences between genders and correlations with gender-specific injury patterns...
March 26, 2024: PM & R: the Journal of Injury, Function, and Rehabilitation
https://read.qxmd.com/read/38529597/the-effects-of-5%C3%A2-minutes-of-static-stretching-on-joint-flexibility-and-muscle-strength-are-comparable-between-ballet-dancers-and-non-dancers
#25
JOURNAL ARTICLE
Takamasa Mizuno, Hiromi Okamoto
Introduction: Ballet dancers have a special morphology, such as a large muscle thickness that affects passive torque. Ballet dancers also possess specialized mechanical, and neural properties of muscles and tendons. These characteristics may produce different static stretching effects than non-dancers. Therefore, this study aimed to determine the differences in the effects of static stretching on joint range of motion, passive torque, and muscle strength between ballet dancers and non-dancers. Methods: This study included 13 ballet dancers and 13 college students...
March 26, 2024: Journal of Dance Medicine & Science
https://read.qxmd.com/read/38529418/matrix-rhythm-therapy-as-a-novel-clinical-approach-in-the-rehabilitation-of-surgically-treated-distal-radius-fracture-a-single-case-study
#26
Pallavi R Bhakaney, Om C Wadhokar, Sakshi Upase
Distal radius fractures (DRFs) are prevalent among all hand injuries, commonly due to a fall on an outstretched hand. Not being treated properly can cause many complications such as malunion, non-union, reduced range of motion, and muscle strength. This case report presents a multidisciplinary approach to the physiotherapeutic management of a DRF treated with closed reduction internal fixation using K-wires. The rehabilitation protocol incorporated matrix rhythm therapy (MRT), a novel therapeutic technique, in combination with targeted therapeutic exercises...
February 2024: Curēus
https://read.qxmd.com/read/38529124/unveiling-the-relationship-of-physical-literacy-with-muscular-fitness-and-muscle-strengthening-activities-in-adolescents-the-ehdla-study
#27
JOURNAL ARTICLE
Emilio Villa-González, Avery D Faigenbaum, José Francisco López-Gil
OBJECTIVE: This study evaluated the relationship between physical literacy (PL) and muscular fitness (MF) as well as muscle-strengthening activities (MSA) in adolescents. METHODS: A secondary cross-sectional study included 823 adolescents (45.1% boys) from the Eating Healthy and Daily Life Activities Study. The Spanish Perceived Physical Literacy Instrument for Adolescents (S-PPLI) assessed the participants' perceived PL. The evaluation of MF in the young population was conducted using the Assessing the Levels of Physical Activity and Fitness (ALPHA-FIT) test battery...
2024: BMJ Open Sport & Exercise Medicine
https://read.qxmd.com/read/38529017/tizanidine-advances-in-pharmacology-therapeutics-and-drug-formulations
#28
REVIEW
Ling-Ling Zhu, Yan-Hong Wang, Quan Zhou
BACKGROUND: Skeletal muscle relaxants (SMRs) are widely used in treating musculoskeletal conditions. All SMRs, with the exception of baclofen and tizanidine, are on the list of 2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults. In our geriatric practice, off-label use of tizanidine as preemptive analgesia drove us to find recent advances in its pharmacology and therapeutics. An update review of tizanidine was thus presented, aiming to bring the latest knowledge to clinicians and promote further research and practical exploration...
2024: Journal of Pain Research
https://read.qxmd.com/read/38527916/rfxcas13d-mediated-inhibition-of-circ1647-alleviates-renal-fibrosis-via-pi3k-akt-signaling-pathway
#29
JOURNAL ARTICLE
Yufang Ni, Hongmin Zhang, Qianwen Xian, Wenjie Qin, Hongwei Su, Li Wang, Jianchun Li
BACKGROUND: Circular RNAs ( CircRNAs ) have been shown to be involved in the development of chronic kidney disease (CKD). This study aimed to investigate the role of Circ1647 in renal fibrosis, which is a hallmark of CKD. METHODS: In this study, we established a unilateral ureteral obstruction (UUO) model and delivered Circ1647 RfxCas13d knockdown plasmid into renal parenchymal cells via retrograde injection through the ureter followed by electroporation. After that, the pathological changes were determined by Hematoxylin and Eosin...
December 2024: Renal Failure
https://read.qxmd.com/read/38527769/infographic-injury-mechanisms-and-situational-patterns-of-severe-lower-limb-muscle-injuries-in-male-professional-football-soccer-players-a-systematic-video-analysis-study-on-103-cases
#30
JOURNAL ARTICLE
Francesco Della Villa, Bruno Massa, Antonio Bortolami, Gianni Nanni, Jesus Olmo, Adam Virgile, Matthew Buckthorpe
No abstract text is available yet for this article.
March 25, 2024: British Journal of Sports Medicine
https://read.qxmd.com/read/38526708/role-of-c-ebp-homologous-protein-in-vascular-stenosis-after-carotid-artery-injury
#31
JOURNAL ARTICLE
Lin Teng, Qin Qin, Zi-Yi Zhou, Fei Zhou, Cun-Yu Cao, Chao He, Jia-Wang Ding, Jian Yang
The study aims to explore the fluctuating expression of C/EBP Homologous Protein (CHOP) following rat carotid artery injury and its central role in vascular stenosis. Using in vivo rat carotid artery injury models and in vitro ischemia and hypoxia cell models employing human aortic endothelial cells (HAECs) and vascular smooth muscle cells (T/G HA-VSMCs), a comprehensive investigative framework was established. Histological analysis confirmed intimal hyperplasia in rat models. CHOP expression in vascular tissues was assessed using Western blot and immunohistochemical staining, and its presence in HAECs and T/G HA-VSMCs was determined through RT-PCR and Western blot...
March 25, 2024: Biochemical Genetics
https://read.qxmd.com/read/38526593/trans-2-nonadecyl-4-hydroxymethyl-1-3-dioxolane-tnhd-purified-from-freshwater-clams-markedly-alleviates-dimethylnitrosamine-induced-hepatic-fibrosis
#32
JOURNAL ARTICLE
Ya-Ru Kuo, Chen-Yu Tsai, Wei-Sheng Lin, Chi-I Chang, Ching-Shu Lai, Min-Hsiung Pan
Liver fibrosis occurs due to injury or inflammation, which results in the excessive production of collagen and the formation of fibrotic scar tissue that impairs liver function. Despite the limited treatment options available, freshwater clams may hold promise in the treatment of liver fibrosis. In this study, we demonstrated the effects of ethanol extract of freshwater clam (FCE), ethyl acetate extract of FCE (EA-FCE), and trans-2-nonadecyl-4-(hydroxymethyl)-1,3-dioxolane (TNHD) on liver fibrosis induced by dimethylnitrosamine (DMN)...
March 15, 2024: Journal of Food and Drug Analysis
https://read.qxmd.com/read/38526390/restoration-of-pregnancy-function-using-gt-pcl-biofilm-in-a-rabbit-model-of-uterine-injury
#33
JOURNAL ARTICLE
Di Huang, Jing Liu, Jie Yang, Junhui Liang, Jing Zhang, Qinyu Han, Jianlong Yu, Tingting Yang, Qi Meng, Thorsten Steinberg, Zhongle Chang, Changzhong Li
Biomaterial scaffolds have been used successfully to promote the regenerative repair of small endometrial lesions in small rodents, providing partial restoration of gestational function. The use of rabbits in this study allowed us to investigate a larger endometrial tissue defect and myometrial-injury model. A gelatin/polycaprolactone (GT/PCL) gradient-layer biofilm was sutured at the defect to guide the reconstruction of the original tissue structure. 28 days post-implantation, the uterine cavity had been restored its original morphology; endometrial growth was accompanied by the formation of glands and blood vessels, and the fragmented myofibers of the uterine smooth muscle had begun to resemble the normal structure of the lagomorph uterine cavity, arranging in a circular luminal pattern and a longitudinal serosal pattern...
March 25, 2024: Tissue Engineering. Part A
https://read.qxmd.com/read/38526145/hyaluronidase-inhibitor-sha2-75-alleviates-ischemia-reperfusion-induced-acute-kidney-injury
#34
JOURNAL ARTICLE
Yang Zhang, Huajiang Zhao, Jing Zhang
Hyaluronidases (HAases) are enzymes that degrade hyaluronic acid (HA) in the animal kingdom. The HAases-HA system is crucial for HA homeostasis and plays a significant role in biological processes and extracellular matrix (ECM)-related pathophysiological conditions. This study aims to explore the role of inhibiting the HAases-HA system in acute kidney injury (AKI). We selected the potent inhibitor "sHA2.75" to inhibit HAase activity through mixed inhibitory mechanisms. The ischemia-reperfusion mouse model was established using male BALB/c mice (7-9 weeks old), and animals were subjected to subcapsular injection with 50 mg/kg sHA2...
March 25, 2024: Cell Cycle
https://read.qxmd.com/read/38525927/prospective-randomized-comparison-of-minimally-invasive-tlif-versus-open-tlif-clinical-effectiveness-and-restoration-of-working-capacity-in-railway-workers
#35
JOURNAL ARTICLE
Vadim A Byvaltsev, Andrei A Kalinin, Yurii Ya Pestryakov, Dmitriy V Hozeev, Rustem A Kundubayev, Mikhail Y Biryuchkov, K Daniel Riew
STUDY DESIGN: Randomized Clinical Trial. OBJECTIVE: To compare the clinical efficacy and restoration of working capacity after MI (minimally invasive)-TLIF and O (open)-TLIF in railway workers with lumbar degenerative disease. METHODS: 83 patients, who were indicated for two-level lumbar decompression and fusion were randomly assigned to one of two groups: group 1 (n = 44) had MI-TLIF procedure and group 2 (n = 39) had O-TLIF procedure. The functional status was assessed using SF-36, ODI and VAS for back and leg pain, preoperatively, at discharge, and at 3, 6, and 12 months postoperatively...
March 25, 2024: Global Spine Journal
https://read.qxmd.com/read/38525510/an-investigation-into-the-frequency-and-risk-factors-of-low-back-pain-following-surgical-treatment-of-isolated-calcaneal-fractures
#36
JOURNAL ARTICLE
Dilek Bayraktar, Cengizhan Özgürbüz, Anıl Murat Öztürk, Salih Kemal Aktuğlu, Nadir Özkayın
OBJECTIVE: This study aimed to determine the frequency of low back pain after calcaneal fractures treated with open reduction internal fixation (ORIF) and the risk factors that cause this condition. METHODS: Thirty-one patients (27 males and 4 females) who underwent surgery for a unilateral calcaneal fracture between 2016 and 2020 and had no complaints of low back pain before fracture surgery were included in the study. The patients were divided into 2 groups: those who developed low back pain after the operation and those who did not...
January 2024: Acta Orthopaedica et Traumatologica Turcica
https://read.qxmd.com/read/38525505/investigation-into-a-new-denervation-model-of-the-sciatic-nerve-zones-in-rats-selective-motor-or-sensorial-denervation
#37
JOURNAL ARTICLE
Selman Hakkı Altuntaş, Levent Sarikcioglu, Hasan Rifat Koyuncuoğlu, İbrahim Metin Çiriş, Fuat Uslusoy, Osman Gurdal, Mustafa Asım Aydın
OBJECTIVE: This study aimed to introduce a reliable and useful model of selective sensorial or motor denervations of the sciatic nerve in rats with clinical and laboratory outcomes. METHODS: The surgical technique was determined via detailed cadaveric dissections of rat sciatic nerve roots and cross-sectional histoanatomy. Forty animals were divided into the sham, sensorial denervation (SD), motor denervation (MD), and combined denervation (CD) groups and evaluated clinically via the pinch test and observation...
January 2024: Acta Orthopaedica et Traumatologica Turcica
https://read.qxmd.com/read/38524704/quadricipital-tendon-simultaneous-bilateral-tear-in-a-patient-with-type-ii-diabetes-mellitus-after-low-energy-trauma-case-report
#38
JOURNAL ARTICLE
Breno Almeida de Pinho Tavares, Leonardo Cortes Antunes, Sara Johanna Sanchez Guerrero, Ângelo José Nascif de Faria, Renato Amorim Carvalho, Rademack Duarte Amorim
Simultaneous bilateral rupture of the quadricipital tendon is an extremely rare lesion. We report a case of this injury after low-energy trauma in a patient with type-II diabetes mellitus. Both knees were surgically approached in the same surgical procedure. Early rehabilitation is essential for the adequate functional recovery of the knee. The aim of the present report was to describe an atypical case of this type of injury after minimal trauma, as well as to detail the surgical technique used to treat it.
February 2024: Revista Brasileira de Ortopedia
https://read.qxmd.com/read/38524673/anabolic-steroids-and-the-evaluation-of-patients-with-acute-pm-tendon-rupture-using-microscopy-and-mri
#39
Alberto de Castro Pochini, Benno Ejnisman, Carlos V Andreoli, Paulo H S Lara, Ivan R B Godoy, Leandro M Ribeiro, Maria T Seixas, Paulo S Belangero, Debora C Hipolide
This study presented a pioneering investigation of the changes in the magnetic resonance imaging images of pectoralis major muscle (PMM) tendon rupture. In all, 26 men were evaluated with acute total PMM rupture (<3 months since injury) with a mean age of 37.3 years (SD = 9.7 years) and 10 control patients with a mean age of 32.6 years (SD = 4.2 years). The evaluation of the tendon PMM injuries was based on the magnetic resonance imaging exam and the histological analysis...
March 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38524505/delayed-neurological-dysfunction-following-posterior-laminectomy-with-lateral-mass-screw-fixation-a-case-report-and-review-of-literature
#40
Rui-Zhong Yan, Chao Chen, Chu-Ran Lin, Yan-Hui Wei, Zhi-Jian Guo, Ya-Kun Li, Quan Zhang, He-Yi Shen, Hao-Lin Sun
BACKGROUND: While most complications of cervical surgery are reversible, some, such as symptomatic postoperative spinal epidural hematoma (SEH), which generally occurs within 24 h, are associated with increased morbidity and mortality. Delayed neurological dysfunction is diagnosed in cases when symptoms present > 3 d postoperatively. Owing to its rarity, the risk factors for delayed neurological dysfunction are unclear. Consequently, this condition can result in irreversible neurological deficits and serious consequences...
March 6, 2024: World Journal of Clinical Cases
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