keyword
https://read.qxmd.com/read/38536784/muscle-strength-during-pregnancy-and-postpartum-in-adolescents-and-adults
#1
JOURNAL ARTICLE
Maria Luiza da Silva Santos, Sabrina Gabrielle Gomes Fernandes Macêdo, Juliana Fernandes, Catherine M Pirkle, Saionara M A Câmara
Adolescent childbirth is associated with worse physical function over the long-term. Differential loss of muscle strength during pregnancy and postpartum for adolescents compared to adults may be one explanation for this, but research examining these differences is lacking. The objective of this study as to assess hand grip strength and hip adduction muscle strength in adolescents and adults during pregnancy and postpartum. A prospective cohort study was carried out with adolescent (13 to 18 years) and adult (23 to 28 years) primigravid women...
2024: PloS One
https://read.qxmd.com/read/38536564/metabolic-consequences-of-anabolic-steroids-insulin-and-growth-hormone-abuse-in-recreational-bodybuilders-implications-for-the-world-anti-doping-agency-passport
#2
JOURNAL ARTICLE
Filippo Giorgio Di Girolamo, Chiara Biasinutto, Alessandro Mangogna, Nicola Fiotti, Pierandrea Vinci, Rado Pisot, Filippo Mearelli, Bostjan Simunic, Chiara Roni, Gianni Biolo
BACKGROUND: Hormonal doping in recreational sports is a public-health concern. The World Anti-Doping Agency (WADA) promoted the creation of the Athlete Biological Passport, aiming to monitor athlete's biological variables over time to facilitate indirect detection of doping. Detection tests for anabolic androgenic steroids (AAS) and growth hormone (GH) are available while insulin abuse cannot be revealed. We have determined in recreational bodybuilders the metabolic effects associated with different patterns of hormone abuse...
March 27, 2024: Sports Medicine—Open
https://read.qxmd.com/read/38536418/imatinib-pharmacokinetics-and-creatine-kinase-levels-in-chronic-myeloid-leukemia-patients-implications-for-therapeutic-response-and-monitoring
#3
JOURNAL ARTICLE
Mervat M Omran, Amel B Ibrahim, Raafat Abdelfattah, Samia A Shouman, Marwa S Hamza
BACKGROUND: Imatinib treatment for certain cancers can lead to elevated creatine kinase (CK) levels, potentially indicating muscle injury, and ongoing research aims to understand the correlation between imatinib levels and creatine kinase to assess its impact on treatment response. METHODS: This single-center observational study involved 76 chronic myeloid leukemia (CML) patients receiving imatinib treatment, focusing on evaluating drug and metabolite levels using liquid chromatography-mass spectrometry (LC-MS-MS) instrumentation...
March 27, 2024: European Journal of Clinical Pharmacology
https://read.qxmd.com/read/38536045/functional-anova-for-upper-extremity-fatigue-analysis-during-dynamic-order-picking
#4
JOURNAL ARTICLE
Setareh Kazemi Kheiri, Zahra Vahedi, Hongyue Sun, Fadel M Megahed, Lora A Cavuoto
OCCUPATIONAL APPLICATIONSMusculoskeletal disorders are prevalent among warehouse workers who engage in repetitive and dynamic tasks. To prevent such injuries, it is vital to identify the factors that influence fatigue in the upper extremities during these repetitive activities. Our study reveals that task factors, namely the bottle mass and picking rate, significantly influence upper extremity fatigue. In most cases, the fatigue indicator is a functional variable, meaning that the fatigue score or measurement is a curve captured over time, which could be modeled as a function...
March 27, 2024: IISE transactions on occupational ergonomics and human factors
https://read.qxmd.com/read/38536012/development-of-a-tannic-acid-and-silicate-ion-functionalized-pva-starch-composite-hydrogel-for-in-situ-skeletal-muscle-repairing
#5
JOURNAL ARTICLE
Longkang Li, Huipeng Li, Zhentian Diao, Huan Zhou, Yanjie Bai, Lei Yang
The repair capacity of skeletal muscle is severely diminished in massive skeletal muscle injuries accompanied by inflammation, resulting in muscle function loss and scar tissue formation. In the current work, we developed a tannic acid (TA)- and silicate ion-functionalized tissue adhesive poly(vinyl alcohol) (PVA)-starch composite hydrogel, referred to as PSTS (PVA-starch-TA-SiO3 2- ). It was formed based on the hydrogen bonding of TA to organic polymers, as well as silicate-TA ligand interaction. PSTS could be gelatinized in minutes at room temperature with crosslinked network formation, making it applicable for injection...
March 27, 2024: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://read.qxmd.com/read/38535741/changes-in-body-composition-and-physical-performance-after-a-six-week-international-tour-in-young-chilean-female-tennis-players
#6
JOURNAL ARTICLE
Pablo Luna-Villouta, Luis Valenzuela Contreras, Cristian Martínez Salazar, Jorge Flández Valderrama, Carlos Matus-Castillo, Carol Flores-Rivera, Marcelo Paredes-Arias, Rodrigo Vargas-Vitoria
Junior tennis players travel a lot to play tennis tournaments; this causes them to spend a lot of time away from their homes and disrupts their training, which could reduce their performance and increase the risk of injury. The purpose of this study was to analyze the changes in physical performance and body composition after a six-week international tour in young Chilean female tennis players. Thirty young female tennis players (15.4 ± 0.6) participated in this study. Body weight, skinfolds, and perimeters were measured...
March 11, 2024: Sports
https://read.qxmd.com/read/38535454/exploring-the-potential-of-crassostrea-nippona-hydrolysates-as-dietary-supplements-for-mitigating-dexamethasone-induced-muscle-atrophy-in-c2c12-cells
#7
JOURNAL ARTICLE
M J M S Kurera, D P Nagahawatta, N M Liyanage, H H A C K Jayawardhana, D S Dissanayake, Hyo-Geun Lee, Young-Sang Kim, Sang In Kang, You-Jin Jeon
Muscle atrophy is a detrimental and injurious condition that leads to reduced skeletal muscle mass and disruption of protein metabolism. Oyster ( Crassostrea nippona ) is a famous and commonly consumed shellfish in East Asia and has become a popular dietary choice worldwide. The current investigation evaluated the efficacy of C. nippona against muscle atrophy, which has become a severe health issue. Mammalian skeletal muscles are primarily responsible for efficient metabolism, energy consumption, and body movements...
February 28, 2024: Marine Drugs
https://read.qxmd.com/read/38535423/inter-set-foam-rolling-of-the-latissimus-dorsi-acutely-increases-repetitions-in-lat-pull-down-exercise-without-affecting-rpe
#8
JOURNAL ARTICLE
Luca Russo, Sebastiano Riccio, Giulio Zecca, Alin Larion, Riccardo Di Giminiani, Johnny Padulo, Cristian Popa, Gian Mario Migliaccio
Foam rolling is widely used in fitness, sports, rehabilitation, and injury prevention. However, there are limited data available on the effect of foam rolling techniques on the upper limbs. The aim of this investigation is to assess the effects of foam rolling the latissimus dorsi area during the rest period between two consecutive lat pull-down exercise (LPDE) sets. Seventeen resistance training experienced volunteer male subjects (25.8 ± 3.4 years; 180.3 ± 9.0 cm; 79.7 ± 9.9 kg) participated in this research...
February 29, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38534963/acrylated-hyaluronic-acid-based-hydrogel-for-the-treatment-of-craniofacial-volumetric-muscle-loss
#9
JOURNAL ARTICLE
Lucas Rohrer, Shinji Kato, Shane Browne, Katharine Striedinger, Kevin E Healy, Jason H Pomerantz
Current treatment options for craniofacial volumetric muscle loss (VML) have disadvantages and cannot fully restore normal function. Bio-inspired semi-synthetic acrylated hyaluronic acid (AcHyA) hydrogel, which fills irregularly shaped defects, resembles an extracellular matrix, and induces a minimal inflammatory response, has shown promise in experimental studies of extremity VML. We therefore sought to evaluate the efficacy of AcHyA hydrogel in the treatment of craniofacial VML. For this, we used a novel model of masseter VML in the rat...
March 27, 2024: Tissue Engineering. Part A
https://read.qxmd.com/read/38534814/a-wearable-upper-limb-exoskeleton-system-and-intelligent-control-strategy
#10
JOURNAL ARTICLE
Qiang Wang, Chunjie Chen, Xinxing Mu, Haibin Wang, Zhuo Wang, Sheng Xu, Weilun Guo, Xinyu Wu, Weimin Li
Heavy lifting operations frequently lead to upper limb muscle fatigue and injury. In order to reduce muscle fatigue, auxiliary force for upper limbs can be provided. This paper presents the development and evaluation of a wearable upper limb exoskeleton (ULE) robot system. A flexible cable transmits auxiliary torque and is connected to the upper limb by bypassing the shoulder. Based on the K-nearest neighbors (KNN) algorithm and integrated fuzzy PID control strategy, the ULE identifies the handling posture and provides accurate active auxiliary force automatically...
February 21, 2024: Biomimetics
https://read.qxmd.com/read/38534564/effects-of-stroboscopic-vision-on-depth-jump-motor-control-a-biomechanical-analysis
#11
JOURNAL ARTICLE
Kenneth D Harrison, Christopher J Dakin, Anne Z Beethe, Talin Louder
Researchers commonly use the 'free-fall' paradigm to investigate motor control during landing impacts, particularly in drop landings and depth jumps (DJ). While recent studies have focused on the impact of vision on landing motor control, previous research fully removed continuous visual input, limiting ecological validity. The aim of this investigation was to evaluate the effects of stroboscopic vision on depth jump (DJ) motor control. Ground reaction forces (GRF) and lower-extremity surface electromyography (EMG) were collected for 20 young adults (11 male; 9 female) performing six depth jumps (0...
March 20, 2024: Bioengineering
https://read.qxmd.com/read/38534337/phosphorylations-and-acetylations-of-cytochrome-c-control-mitochondrial-respiration-mitochondrial-membrane-potential-energy-ros-and-apoptosis
#12
REVIEW
Paul T Morse, Tasnim Arroum, Junmei Wan, Lucynda Pham, Asmita Vaishnav, Jamie Bell, Lauren Pavelich, Moh H Malek, Thomas H Sanderson, Brian F P Edwards, Maik Hüttemann
Cytochrome c (Cyt c ) has both life-sustaining and cellular death-related functions, depending on subcellular localization. Within mitochondria, Cyt c acts as a single electron carrier as part of the electron transport chain (ETC). When released into the cytosol after cellular insult, Cyt c triggers the assembly of the apoptosome, committing the cell to intrinsic apoptosis. Due to these dual natures, Cyt c requires strong regulation by the cell, including post-translational modifications, such as phosphorylation and acetylation...
March 12, 2024: Cells
https://read.qxmd.com/read/38533529/adar2-deficiency-ameliorates-non-alcoholic-fatty-liver-disease-and-muscle-atrophy-through-modulating-serum-amyloid-a1
#13
JOURNAL ARTICLE
Mei-Lang Kung, Tai-Hua Yang, Chia-Chi Lin, Jia-Yun Ho, Tzu-Chi Hung, Chih-Hsiang Chang, Kuan-Wen Huang, Chien-Chin Chen, Yun-Wen Chen
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, which is commonly associated with NAFLD. Adenosine-to-inosine editing, catalysed by adenosine deaminase acting on RNA (ADAR), is an important post-transcriptional modification of genome-encoded RNA transcripts. Three ADAR gene family members, including ADAR1, ADAR2 and ADAR3, have been identified...
March 27, 2024: Journal of Cachexia, Sarcopenia and Muscle
https://read.qxmd.com/read/38533161/effectiveness-of-recent-physiotherapy-techniques-along-with-conventional-physiotherapy-techniques-in-a-patient-with-knee-osteoarthritis-a-case-report
#14
Kamya J Somaiya, Subrat Samal, Manali A Boob
Osteoarthritis (OA), the most common joint disease, lowers quality of life, restricts social activity participation, and results in incapacity. Osteoarthritis is characterised by changes in subchondral bone, meniscus degeneration, cartilage loss, and synovial inflammation. Physiotherapy plays a vital role in maintaining the stability of this disease. Various treatment approaches have been shown in numerous studies to be successful in improving the condition of individuals with osteoarthritis in the knee. We are presenting a case of a 47-year-old woman who had bilateral osteoarthritis in her knees...
February 2024: Curēus
https://read.qxmd.com/read/38532992/peripheral-nerve-stimulation-for-the-treatment-of-superior-cluneal-neuralgia-a-cadaver-demonstration-of-a-novel-technique-for-lead-placement
#15
JOURNAL ARTICLE
Alaa Abd-Elsayed, Michael J Gyorfi
Superior cluneal neuralgia (SCN) is a distinct cause of lower back and/or leg pain related to pathology of the superior cluneal nerve. When assessing a patient with low back pain (LBP), superior cluneal neuralgia is frequently misdiagnosed. The pathophysiology of SCN ranges from myofascial compression brought on by aberrant muscle tone to direct iatrogenic injury or trauma. In this technical report we will discuss the anatomy of superior cluneal nerve, superior cluneal neuralgia, current treatment modalities, and a novel approach to peripheral nerve stimulation (PNS) lead placement via a cadaver demonstration for SCN...
2024: Journal of Pain Research
https://read.qxmd.com/read/38532871/injury-epidemiology-in-beach-tennis-incidence-and-risk-factors
#16
JOURNAL ARTICLE
Fabio Lucas Rodrigues, Paulo Sergio Barone, Ramylla Saldanha Penha, Isabela Pagliaro Franco
INTRODUCTION: Due to the growing increase in beach tennis practice in Brazil and the lack of studies on the injuries that occur in this sport, it has become necessary to develop more research on the subject. OBJECTIVE: to identify risk and protection factors for injuries in beach tennis, in order to generate prevention strategies for musculoskeletal injuries. METHOD: A cross-sectional epidemiological study, level 3 of evidence, was carried out through an electronic form with 698 Beach Tennis players, who answered questions about their relationship with the practice of the sport and occurrences of injuries...
2024: Acta Ortopedica Brasileira
https://read.qxmd.com/read/38532869/clinical-and-functional-evaluation-of-wrists-and-hands-of-spinal-cord-injured-patients
#17
JOURNAL ARTICLE
Cíntia Kelly Bittar, Isabela Ferreira Perucci, Danillo Nagel Signorini, Mariana Buratti Mascarenhas, Orcizo Francisco Silvestre, Alberto Cliquet
INTRODUCTION: The inability of the spinal cord to propagate sensory and motor stimuli as a result of the disruption of the nerve tracts is called spinal cord injury. OBJECTIVE: This study analyzes clinically and radiologically the hands and wrists of spinal cord injured patients, evaluating their motor and sensitive functionality, in order to determine if these patients are more likely to develop degenerative alterations. METHODS: 14 patients (8 paraplegics and 6 tetraplegics) were evaluated, undergoing anamnesis and clinical examination - a scale of muscular strength (MRC - Medical Research Council) and the amplitude measurement of the movement with a manual goniometer (ROM), were used for objective evaluation - and x-ray exams...
2024: Acta Ortopedica Brasileira
https://read.qxmd.com/read/38532253/heterotopic-ossification-of-the-abdomen-a-rare-sequela-following-trauma-and-damage-control-laparotomy
#18
JOURNAL ARTICLE
Patrick Cherfan, Michael D Cobler-Lichter, Joshua P Kronenfeld, Zoe Weiss, Patricia M Byers
Heterotopic ossification (HO) of the abdomen is a rare yet highly morbid complication following blunt and penetrating trauma requiring damage control laparotomy. We present the case of a 22-year-old man, 20 months after life-threatening motor vehicle crash with major vascular injury requiring multiple abdominal surgeries. The patient was initially treated at a community hospital and subsequently developed a chronic left lower quadrant enterocutaneous fistula, accompanied by a gradually worsening diffuse abdominal pain...
March 26, 2024: American Surgeon
https://read.qxmd.com/read/38532207/development-of-a-screening-system-of-gene-sets-for-estimating-the-time-of-early-skeletal-muscle-injury-based-on-second-generation-sequencing-technology
#19
JOURNAL ARTICLE
Junyi Shen, Hao Sun, Shidong Zhou, Liangliang Wang, Chaoxiu Dong, Kang Ren, Qiuxiang Du, Jie Cao, Yingyuan Wang, Junhong Sun
The present study is aimed to address the challenge of wound age estimation in forensic science by identifying reliable genetic markers using low-cost and high-precision second-generation sequencing technology. A total of 54 Sprague-Dawley rats were randomly assigned to a control group or injury groups, with injury groups being further divided into time points (4 h, 8 h, 12 h, 16 h, 20 h, 24 h, 28 h, and 32 h after injury, n = 6) to establish rat skeletal muscle contusion models...
March 27, 2024: International Journal of Legal Medicine
https://read.qxmd.com/read/38531801/lncrna-meg3-aggravates-renal-fibrosis-caused-by-unilateral-ureteral-obstruction-in-rats-by-activating-the-hedgehog-pathway
#20
JOURNAL ARTICLE
Pei Dong, Sheng Zhang, Da-Jun Hu, Rui Hou, Li Lei
BACKGROUND: The hedgehog signaling pathway exerts vital functions in regulating epithelial-to-mesenchymal transition (EMT) in renal interstitial fibrosis (RIF). It was reported that lncRNA-maternally expressed gene 3 (lncRNA Meg3) can regulate hepatic fibrosis by regulating the expression of smoothened (Smo) in the hedgehog signaling pathway. However, the specific role of lncRNA Meg3 in renal fibrosis resulting from unilateral ureteral obstruction (UUO) by regulating the hedgehog signaling pathway has not been reported...
March 2024: Discovery Medicine
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