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Calibration logistic regression

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https://www.readbyqxmd.com/read/28093430/development-and-validation-of-a-prediction-model-for-gestational-hypertension-in-a-ghanaian-cohort
#1
Edward Antwi, Rolf H H Groenwold, Joyce L Browne, Arie Franx, Irene A Agyepong, Kwadwo A Koram, Kerstin Klipstein-Grobusch, Diederick E Grobbee
OBJECTIVE: To develop and validate a prediction model for identifying women at increased risk of developing gestational hypertension (GH) in Ghana. DESIGN: A prospective study. We used frequencies for descriptive analysis, χ(2) test for associations and logistic regression to derive the prediction model. Discrimination was estimated by the c-statistic. Calibration was assessed by calibration plot of actual versus predicted probability. SETTING: Primary care antenatal clinics in Ghana...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28081544/nomogram-to-predict-pathologic-complete-response-in-her2-positive-breast-cancer-treated-with-neoadjuvant-systemic-therapy
#2
Takeo Fujii, Takahiro Kogawa, Jimin Wu, Aysegul A Sahin, Dian D Liu, Mariana Chavez-MacGregor, Sharon H Giordano, Akshara Raghavendra, Rushmy K Murthy, Debu Tripathy, Yu Shen, Jose-Miguel Yamal, Naoto T Ueno
BACKGROUND: Pathologic complete response (pCR) is associated with improved survival outcomes in patients with HER2-positive primary breast cancer. We developed a nomogram to predict the probability of pCR rates by using oestrogen receptor (ER) expression, progesterone receptor (PR) expression and HER2/CEP17 ratio as continuous variables. METHODS: We retrospectively reviewed patients with stages I-III HER2-positive invasive breast cancer who had definitive surgery in 1999-2015 and received neoadjuvant systemic therapy (NST)...
January 12, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28081211/development-and-validation-of-a-clinical-prediction-rule-for-bacteremia-among-maintenance-hemodialysis-patients-in-outpatient-settings
#3
Sho Sasaki, Takeshi Hasegawa, Hiroo Kawarazaki, Atsushi Nomura, Daisuke Uchida, Takahiro Imaizumi, Masahide Furusho, Hiroki Nishiwaki, Shingo Fukuma, Yugo Shibagaki, Shunichi Fukuhara
BACKGROUND: To our knowledge, no reliable clinical prediction rule (CPR) for identifying bacteremia in hemodialysis (HD) patients has been established. The aim of this study was to develop a CPR for bacteremia in maintenance HD patients visiting the outpatient department. METHODS: This multicenter cohort study involved consecutive maintenance HD patients who visited the outpatient clinic or emergency room of seven Japanese institutions between August 2011 and July 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28079580/a-predictive-model-for-extended-postanesthesia-care-unit-length-of-stay-in-outpatient-surgeries
#4
Rodney A Gabriel, Ruth S Waterman, Jihoon Kim, Lucila Ohno-Machado
BACKGROUND: A predictive model that can identify patients who are at an increased risk for prolonged postanesthesia care unit (PACU) stay could help optimize resource utilization and case sequencing. Although previous studies identified some predictors, there is not a model that only utilizes various patients demographic and comorbidities, that are already known preoperatively, and that may affect PACU length of stay for outpatient procedures requiring the care of an anesthesiologist...
January 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28073820/predicting-6-month-mortality-risk-of-patients-commencing-dialysis-treatment-for-end-stage-kidney-disease
#5
Sara E Ivory, Kevan R Polkinghorne, Yeasmin Khandakar, Jessica Kasza, Sophia Zoungas, Retha Steenkamp, Paul Roderick, Rory Wolfe
BACKGROUND: There is evidence that end-stage kidney disease patients who are older or with more comorbidity may have a poor trade-off between benefits of dialysis and potential harms. We aimed to develop a tool for predicting patient mortality in the early stages of receiving dialysis. METHODS: In 23 658 patients aged 15+ years commencing dialysis between 2000 and 2009 in Australia and New Zealand a point score tool was developed to predict 6-month mortality based on a logistic regression analysis of factors available at dialysis initiation...
January 10, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28052940/endometrial-cancer-risk-factors-hormone-receptors-and-mortality-prediction
#6
Evan L Busch, Marta Crous-Bou, Jennifer Prescott, Maxine M Chen, Michael J Downing, Bernard Rosner, George L Mutter, Immaculata De Vivo
BACKGROUND: Endometrial tumors arise from a hormonally-responsive tissue. Defining subtypes by hormone receptors might better inform etiology and prediction of patient outcomes. We evaluated the potential role of tumor estrogen receptor (ER) and progesterone receptor (PR) expression to define endometrial cancer subtypes. METHODS: We measured semi-continuous ER and PR protein expression in tissue specimens from 360 endometrial primary tumors from the Nurses' Health Study...
January 4, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28052412/identifying-potentially-avoidable-readmissions-a-medication-based-15-day-readmission-risk-stratification-algorithm
#7
Sreemanee Raaj Dorajoo, Vincent See, Chen Teng Chan, Joyce Zhenyin Tan, Doreen Su Yin Tan, Siti Maryam Binte Abdul Razak, Ting Ting Ong, Narendran Koomanan, Chun Wei Yap, Alexandre Chan
BACKGROUND: Stratifying patients according to 15-day readmission risk would be useful in identifying those who may benefit from targeted interventions during and/or following hospital discharge that are designed to reduce the likelihood of readmission. METHODS: A prediction model was derived via a case-control analysis of patients discharged from a tertiary hospital in Singapore using multivariate logistic regression. The model was validated in two independent external cohorts separated temporally and geographically...
January 4, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28046017/development-and-external-validation-of-the-korean-prostate-cancer-risk-calculator-for-high-grade-prostate-cancer-comparison-with-two-western-risk-calculators-in-an-asian-cohort
#8
Jae Young Park, Sungroh Yoon, Man Sik Park, Hoon Choi, Jae Hyun Bae, Du Geon Moon, Sung Kyu Hong, Sang Eun Lee, Chanwang Park, Seok-Soo Byun
PURPOSE: We developed the Korean Prostate Cancer Risk Calculator for High-Grade Prostate Cancer (KPCRC-HG) that predicts the probability of prostate cancer (PC) of Gleason score 7 or higher at the initial prostate biopsy in a Korean cohort (http://acl.snu.ac.kr/PCRC/RISC/). In addition, KPCRC-HG was validated and compared with internet-based Western risk calculators in a validation cohort. MATERIALS AND METHODS: Using a logistic regression model, KPCRC-HG was developed based on the data from 602 previously unscreened Korean men who underwent initial prostate biopsies...
2017: PloS One
https://www.readbyqxmd.com/read/28043766/re-operative-urethroplasty-after-failed-hypospadias-repair-how-prior-surgery-impacts-risk-for-additional-complications
#9
W Snodgrass, N C Bush
PURPOSE: The primary aim of this report was to compare urethroplasty complications for primary distal and proximal repairs with those after 1, 2, 3, and 4 or more re-operations. METHODS: Prospectively collected data on consecutive hypospadias repairs (tubularized incised plate (TIP), inlay, two-stage graft) from 2000 to 2015 were reviewed. Isolated fistula closures were excluded. Extracted information included patient age, meatal location, repair type, primary vs...
December 7, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28043662/a-novel-risk-score-model-for-prediction-of-contrast-induced-nephropathy-after-emergent-percutaneous-coronary-intervention
#10
Kai-Yang Lin, Wei-Ping Zheng, Wei-Jie Bei, Shi-Qun Chen, Sheikh Mohammed Shariful Islam, Yong Liu, Lin Xue, Ning Tan, Ji-Yan Chen
BACKGROUND: A few studies developed simple risk model for predicting CIN with poor prognosis after emergent PCI. The study aimed to develop and validate a novel tool for predicting the risk of contrast-induced nephropathy (CIN) in patients undergoing emergent percutaneous coronary intervention (PCI). METHODS: 692 consecutive patients undergoing emergent PCI between January 2010 and December 2013 were randomly (2:1) assigned to a development dataset (n=461) and a validation dataset (n=231)...
December 26, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28034691/glycaemic-control-in-sudanese-individuals-with-type-2-diabetes-population-based-study
#11
Sufian K Noor, Wadie M Elmadhoun, Sarra O Bushara, Ahmed O Almobarak, Reham S Salim, Sittana A Forawi, Heitham Awadallah, Einas S Elwali, Mohamed H Ahmed
BACKGROUND: Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. The objective of this study was to determine the prevalence of glycaemic control among individuals with type 2 diabetes across different cities in Sudan. METHODS: Individuals with type 2 diabetes attending selected diabetes centres in Sudan, who had been on treatment for DM for at least one year and volunteered to participate were included. Participants were interviewed using standardized pretested questionnaire to record medical history, sociodemographic and life style characteristics...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28012538/assessment-of-complete-unilateral-cleft-lip-and-palate-patients-determination-of-factors-effecting-dental-arch-relationships
#12
Anas Imran Arshad, Mohammad Khursheed Alam, Mohd Fadhli Khamis
OBJECTIVES: The purpose of the current study was to assess the treatment outcome of non-syndromic patients having complete unilateral cleft lip and palate (CUCLP) by using GOSLON index and to determine any association of pre and/or postnatal factors with the treatment outcome. MATERIALS AND METHODS: One hundred and one sets of dental models of patients having CUCLP were assessed in this retrospective study. Five examiners that were blinded to case-specific information scored the dental models at two instances with an interval of two weeks to ensure memory bias elimination (5 × 101 × 2 = 1010 observations)...
January 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28007407/variable-selection-methods-for-multiple-regressions-influence-the-parsimony-of-risk-prediction-models-for-cardiac-surgery
#13
Md Nazmul Karim, Christopher M Reid, Lavinia Tran, Andrew Cochrane, Baki Billah
OBJECTIVE: To compare the impact of different variable selection methods in multiple regression to develop a parsimonious model for predicting postoperative outcomes of patients undergoing cardiac surgery. METHODS: Data from 84,135 patients in the Australian and New Zealand Society of Cardiac and Thoracic Surgeons registry between 2001 and 2014 were analyzed. Primary outcome was 30-day-mortality. Mixed-effect logistic regressions were used to build the model. Missing values were imputed by the use of multiple imputations...
November 19, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28002683/a-prediction-model-to-help-with-the-assessment-of-adenopathy-in-lung-cancer-hal
#14
Oisin J O'Connell, Francisco A Almeida, Michael J Simoff, Lonny Yarmus, Ray Lazarus, Benjamin Young, Yu Chen, Roy Semaan, Timothy M Saettele, Joseph Cicenia, Harmeet Bedi, Corrine Kliment, Liang Li, Sonali Sethi, Javier Diaz-Mendoza, David Feller-Kopman, Juhee Song, Thomas Gildea, Hans Lee, Horiana B Grosu, Michael Machuzak, Macarena Rodriguez-Vial, George A Eapen, Carlos A Jimenez, Roberto F Casal, David E Ost
RATIONALE: Estimating the probability of finding N2 or N3 (prN2/3) malignant nodal disease on EBUS-TBNA in patients with non-small cell lung cancer (NSCLC) can facilitate the selection of subsequent management strategies. OBJECTIVE: The goal of this study was to develop a clinical prediction model for estimating the prN2/3. METHODS: We used the AQuIRE registry to identify patients with NSCLC with clinical radiographic stage T1-3, N0-3, M0 disease that had EBUS-TBNA for staging...
December 21, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27999959/validation-of-trauma-scales-iss-niss-rts-and-triss-for-predicting-mortality-in-a-colombian-population
#15
Carlos Oliver Valderrama-Molina, Nelson Giraldo, Alfredo Constain, Andres Puerta, Camilo Restrepo, Alba León, Fabián Jaimes
BACKGROUND: Our purpose was to validate the performance of the ISS, NISS, RTS and TRISS scales as predictors of mortality in a population of trauma patients in a Latin American setting. MATERIALS AND METHODS: Subjects older than 15 years with diagnosis of trauma, lesions in two or more body areas according to the AIS and whose initial attention was at the hospital in the first 24 h were included. The main outcome was inpatient mortality. Secondary outcomes were admission to the intensive care unit, requirement of mechanical ventilation and length of stay...
December 20, 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27995881/-establishment-and-assessment-of-a-nomogram-for-predicting-the-differentiation-syndrome-of-acute-promyelocytic-leukemia
#16
X B Bao, X H Hu, C Y Tian, Y H Ji, S N Chen, H Y Qiu, A N Sun, D P Wu
Objective: By analyzing the risk factors for occurrence of differentiation syndrome (DS) during induction therapy in newly-diagnosed acute promyelocytic leukemia (APL) patients, a prediction nomogram for DS was established and the accuracy of this nomogram was validated. Methods: The modeling group was made up of 130 classical APL patients during the period of 1st January 2011 to 31st December 2013. After single factor screening of clinical variables, the logistic regression model was used to identify the final model variables...
November 14, 2016: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/27992611/a-nomogram-to-predict-adequate-lymph-node-recovery-before-resection-of-colorectal-cancer
#17
Zhen-Yu Zhang, Cong Li, Wei Gao, Xiao-Wei Yin, Qi-Feng Luo, Nan Liu, Shiva Basnet, Zhen-Ling Dai, Hai-Yan Ge
Increased lymph node count (LNC) has been associated with prolonged survival in colorectal cancer (CRC), but the underlying mechanisms are still poorly understood. The study aims to identify new predictors and develop a preoperative nomogram for predicting the probability of adequate LNC (≥ 12). 501 eligible patients were retrospectively selected to identify clinical-pathological factors associated with LNC ≥ 12 through univariate and multivariate logistic regression analyses. The nomogram was built according to multivariate analyses of preoperative factors...
2016: PloS One
https://www.readbyqxmd.com/read/27987514/-effects-of-breast-feeding-duration-bottle-feeding-duration-and-oral-habits-on-the-occlusal-characteristics-of-primary-dentition
#18
X X Chen, B Xia, L H Ge, J W Yuan
OBJECTIVE: To assess the effects of breast-feeding duration, bottle-feeding duration and oral habits on the occlusal characteristics of primary dentition in 3-6-year-old children in Beijing. METHODS: This cross sectional study was conducted via an examination of the occlusal characteristics of 734 children combined with a questionnaire completed by their parents/guardians. The examination was performed by a single, previously calibrated examiner and the following variables were evaluated: presence or absence of deep overbite, open bite, anterior cross bite, posterior cross bite, deep overjet, terminal plane relationship of the second primary molar, primary canine relationship, crowding and spacing...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27976604/acceptability-and-potential-effectiveness-of-commercial-portion-control-tools-amongst-people-with-obesity
#19
Eva Almiron-Roig, Angélica Domínguez, David Vaughan, Ivonne Solis-Trapala, Susan A Jebb
Exposure to large portion sizes is a risk factor for obesity. Specifically designed tableware may modulate how much is eaten and help with portion control. We examined the experience of using a guided crockery set (CS) and a calibrated serving spoon set (SS) by individuals trying to manage their weight. Twenty-nine obese adults who had completed 7-12 weeks of a community weight-loss programme were invited to use both tools for 2 weeks each, in a crossover design, with minimal health professional contact. A paper-based questionnaire was used to collect data on acceptance, perceived changes in portion size, frequency, and type of meal when the tool was used...
December 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27976388/covariate-balancing-through-naturally-occurring-strata
#20
Farrokh Alemi, Amr ElRafey, Ivan Avramovic
OBJECTIVE: To provide an alternative to propensity scoring (PS) for the common situation where there are interacting covariates. SETTING: We used 1.3 million assessments of residents of the United States Veterans Affairs nursing homes, collected from January 1, 2000, through October 9, 2012. DESIGN: In stratified covariate balancing (SCB), data are divided into naturally occurring strata, where each stratum is an observed combination of the covariates...
December 14, 2016: Health Services Research
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