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https://www.readbyqxmd.com/read/28110313/framework-for-2d-3d-image-fusion-of-infrared-thermography-with-preoperative-mri
#1
Nico Hoffmann, Florian Weidner, Peter Urban, Tobias Meyer, Christian Schnabel, Yordan Radev, Gabriele Schackert, Uwe Petersohn, Edmund Koch, Stefan Gumhold, Gerald Steiner, Matthias Kirsch
Multimodal medical image fusion combines information of one or more images in order to improve the diagnostic value. While previous applications mainly focus on merging images from computed tomography, magnetic resonance imaging (MRI), ultrasonic and single-photon emission computed tomography, we propose a novel approach for the registration and fusion of preoperative 3D MRI with intraoperative 2D infrared thermography. Image-guided neurosurgeries are based on neuronavigation systems, which further allow us track the position and orientation of arbitrary cameras...
January 23, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28110267/ceratopetalum-cunoniaceae-fruits-of-australasian-affinity-from-the-early-eocene-laguna-del-hunco-flora-patagonia-argentina
#2
REVIEW
María A Gandolfo, Elizabeth J Hermsen
BACKGROUND AND AIMS: Radially symmetrical, five-winged fossil fruits from the highly diverse early Eocene Laguna del Hunco flora of Chubut Province, Patagonia, Argentina, are named, described and illustrated. The main goals are to assess the affinities of the fossils and to place them in an evolutionary, palaeoecological and biogeographic context. METHODS: Specimens of fossil fruits were collected from the Tufolitas Laguna del Hunco. They were prepared, photographed and compared with similar extant and fossil fruits using published literature...
January 20, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28109564/development-of-a-surgical-navigation-system-based-on-3d-slicer-for-intraoperative-implant-placement-surgery
#3
Xiaojun Chen, Lu Xu, Huixiang Wang, Fang Wang, Qiugen Wang, Ron Kikinis
Implant placement has been widely used in various kinds of surgery. However, accurate intraoperative drilling performance is essential to avoid injury to adjacent structures. Although some commercially-available surgical navigation systems have been approved for clinical applications, these systems are expensive and the source code is not available to researchers. 3D Slicer is a free, open source software platform for the research community of computer-aided surgery. In this study, a loadable module based on Slicer has been developed and validated to support surgical navigation...
January 18, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28108802/opportunistic-screening-for-osteoporosis-by-routine-ct-in-southern-europe
#4
Elena Alacreu, David Moratal, Estanislao Arana
: Feasibility evaluation of early detection of osteoporosis in oncologic patients by bone mineral density (BMD) on abdominal computed tomography (CT) scans performed for other clinical indications, by using dual-energy X-ray absorptiometry (DXA) as reference. Abdominal CT images can identify patients with osteoporosis BMD without additional radiation exposure or cost. INTRODUCTION: The purpose of the study is to evaluate the feasibility of early detection of osteoporosis by bone mineral density (BMD) on abdominal computed tomography (CT) scans performed in oncologic patients, comparing calibrated and uncalibrated measurements by using dual-energy X-ray absorptiometry (DXA) as reference...
January 20, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28108082/analysis-of-drugs-of-abuse-in-human-plasma-using-microextraction-by-packed-sorbents-and-ultra-high-performance-liquid-chromatography
#5
P Fernández, M González, M Regenjo, A M Ares, A M Fernández, R A Lorenzo, A M Carro
A miniaturized and simple method based on digitally programmed microextraction by packed sorbent (eVol(®)-MEPS) coupled to ultra-performance liquid chromatography (UPLC) has been developed for quantitative determination of three synthetic cathinones and seven conventional drugs of abuse and metabolites. The influence of several extraction parameters, such as washing and elution solvents were tested. In addition important variables affecting MEPS performance, namely sample volume, sorbent drying time, washing solvent volume, elution volume, number of extraction cycles, sorbent phase and pH, were evaluated using an asymmetrical screening design...
January 16, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28108027/a-postoperative-scoring-system-for-distant-recurrence-in-node-positive-cervical-cancer-patients-after-radical-hysterectomy-and-pelvic-lymph-node-dissection-with-para-aortic-lymph-node-sampling-or-dissection
#6
Young-Jae Lee, Dae-Yeon Kim, Shin-Wha Lee, Jeong-Yeol Park, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Young-Tak Kim, Joo-Hyun Nam
OBJECTIVE: To identify risk factors for distant recurrence in node-positive cervical cancer patients who underwent radical hysterectomy and pelvic lymph node dissection (PLND) with para-aortic lymph node sampling (PALNS) or para-aortic lymph node dissection (PALND). METHODS: A total of 299 patients in whom lymph node metastasis was confirmed after radical surgery at Asan Medical Center for stage IA2 to IIB cervical cancer from February 2001 to December 2012 were identified...
January 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28108009/which-factors-are-most-predictive-for-live-birth-after-in%C3%A2-vitro-fertilization-and-intracytoplasmic-sperm-injection-ivf-icsi-treatments-analysis-of-100-prospectively-recorded-variables-in-8-400-ivf-icsi-single-embryo-transfers
#7
Katarina Kebbon Vaegter, Tatevik Ghukasyan Lakic, Matts Olovsson, Lars Berglund, Thomas Brodin, Jan Holte
OBJECTIVE: To construct a prediction model for live birth after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment and single-embryo transfer (SET) after 2 days of embryo culture. DESIGN: Prospective observational cohort study. SETTING: University-affiliated private infertility center. PATIENT(S): SET in 8,451 IVF/ICSI treatments in 5,699 unselected consecutive couples during 1999-2014. INTERVENTION(S): A total of 100 basal patient characteristics and treatment data were analyzed for associations with live birth after IVF/ICSI (adjusted for repeated treatments) and subsequently combined for prediction model construction...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28107999/determination-of-sulfonamides-in-animal-tissues-by-modified-quechers-and-liquid-chromatography-tandem-mass-spectrometry
#8
Ching-Hsuan Wen, Shu-Ling Lin, Ming-Ren Fuh
In this study, the salting-out solvent extraction and dispersive solid-phase extraction (dSPE) clean-up steps in QuEChERS (quick, easy, cheap, effective, rugged, and safe) method were optimized to reduce matrix effect and efficiently extract target sulfonamides from a variety of edible animal tissues. The extracted sulfonamides were then analyzed using liquid chromatography tandem mass spectrometry (LC-MS/MS). Good extraction recoveries (74.0-100.3% in five different sources of animal tissues; n=3) with acceptable matrix effect (<10%, except for liver samples) were obtained using the proposed method...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107987/generation-of-biostable-l-aptamers-against-achiral-targets-by-chiral-inversion-of-existing-d-aptamers
#9
Huapei Chen, Sitao Xie, Hao Liang, Cuichen Wu, Liang Cui, Shuang-Yan Huan, Xiaobing Zhang
In this paper, based on reciprocal chiral substrate specificity, taking achiral molecules, ethanolamine (EA) and malachite green (MG) as two model targets, biostable L- DNA aptamers and L-RNA aptamers were generated respectively by chiral inversion of existing D-aptamers. In the detection of EA with L-DNA aptamer-based sensors, the feasibility of our strategy was confirmed, while in the detection of MG with L-RNA aptamers, linear calibration curves were obtained in the range from 0.1 to 5µm with the detection limit of 0...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107986/dispersive-solid-phase-extraction-using-polyaniline-modified-zeolite-nay-as-a-new-sorbent-for-multiresidue-analysis-of-pesticides-in-food-and-environmental-samples
#10
Prapha Arnnok, Nopbhasinthu Patdhanagul, Rodjana Burakham
The applicability of polyaniline (PANI)-modified zeolite NaY as a sorbent for multi-class pesticides extraction was investigated. The sorbent had a sorption capacity of 833mgkg(-1) sorbent and preconcentration factor of 42 in the mixture of twenty pesticides. The PANI-coated zeolite NaY was successfully created via oxidative polymerization of aniline onto the surface of the zeolite. The sorbent was applied for dispersive solid phase extraction (DSPE) of commonly used pesticides belonging to five different chemical groups, involving carbamate, organophosphate, sulfonylurea, pyrethroid and neonicotinoid...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107979/electrochemical-sensing-platform-based-on-molecularly-imprinted-polymer-decorated-n-s-co-doped-activated-graphene-for-ultrasensitive-and-selective-determination-of-cyclophosphamide
#11
Bintong Huang, Lili Xiao, Haifeng Dong, Xueji Zhang, Wei Gan, Shahid Mahboob, Khalid Abdullah Al-Ghanim, Qunhui Yuan, Yingchun Li
A novel electrochemical sensor has been facilely fabricated by applying composite elements consisting of nitrogen and sulfur co-doped activated graphene (N,S-AGR) and molecularly imprinted polymer (MIP). N,S-AGR was synthesized by one-pot pyrogenation of a mixture of thiourea, KOH and graphene oxide, which was introduced to improve electron transfer capability and surface area of the electrode, while the electro-polymerized MIP layer afforded simultaneous recognition and quantification of cyclophosphamide (CPA) by utilizing Fe(CN)6(3-/4-) as probe to indicate electrical signals...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107975/comparison-of-sample-preparation-strategies-for-target-analysis-of-total-thyroid-hormones-levels-in-serum-by-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry
#12
E Álvarez, Y Madrid, M D Marazuela
This paper describes a novel method based on liquid chromatography quadrupole time-of-flight-mass spectrometry (LC-QTOF-MS) for target analysis of total THs in serum. Several sample preparation strategies have been evaluated to reduce matrix effect (namely, HybridSPE cartridges, supported liquid extraction, SLE and solid phase extraction, SPE). Deproteinization and further clean-up with mixed-mode SPE was selected as the best strategy for sample preparation, since achieved the cleanest extracts and reduced ionization suppression effects (between -11 and -24%)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107943/development-of-a-nanoarray-capable-of-the-rapid-and-simultaneous-detection-of-zearalenone-t2-toxin-and-fumonisin
#13
Sara E McNamee, Francesca Bravin, Giulia Rosar, Christopher T Elliott, Katrina Campbell
Fusarium mycotoxins such as trichothecenes, zearalenone and fumonisins occur on a worldwide basis in cereal grains, animal feeds and forages. Practical solutions for multiple mycotoxin determination in samples are required by industry and regulators for cost effective screening purposes. The feasibility of developing a novel multiplex nanoarray for the simultaneous and semi-quantitative detection of three regulated mycotoxins: zearalenone (ZEA), T2-toxin (T2) and fumonisin B1 (FUM) was examined. Additionally, the assay was also able to detect HT2 toxin and fumonisin B2 and B3 due to the cross reactivity profiles of the antibodies used...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107937/calibration-free-quantitative-analysis-of-elemental-ratios-in-intermetallic-nanoalloys-and-nanocomposites-using-laser-induced-breakdown-spectroscopy-libs
#14
Seyyed Ali Davari, Sheng Hu, Dibyendu Mukherjee
Intermetallic nanoalloys (NAs) and nanocomposites (NCs) have increasingly gained prominence as efficient catalytic materials in electrochemical energy conversion and storage systems. But their morphology and chemical compositions play critical role in tuning their catalytic activities, and precious metal contents. While advanced microscopy techniques facilitate morphological characterizations, traditional chemical characterizations are either qualitative or extremely involved. In this study, we apply Laser Induced Breakdown Spectroscopy (LIBS) for quantitative compositional analysis of NAs and NCs synthesized with varied elemental ratios by our in-house built pulsed laser ablation technique...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107935/tetraphasic-polar-organic-chemical-integrative-sampler-for-the-determination-of-a-wide-polarity-range-organic-pollutants-in-water-the-use-of-performance-reference-compounds-and-in-situ-calibration
#15
A Iparraguirre, A Prieto, A Vallejo, M Moeder, O Zuloaga, N Etxebarria, A Paschke
In the present work, a homemade polar organic chemical integrative sampler (POCIS) was studied for the determination of 16 target analytes. The suitability of the combination of triphasic mixture (used in so called pesticides-POCIS) and octadecyl-functionalized silica gel (C18) as sorbent for POCIS was evaluated for the determination of alkylphenols (APs), several hormones, bisphenol-A (BPA), synthetic musk fragrances and herbicides such as trifluralin (Tri) and alachlor (Ala). With this purpose, POCIS laboratory calibration study, using a continuous-flow calibration system, was carried out in order to determine the uptake behavior and sampling rate (Rs) values for each target analyte...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107927/electrochemical-detection-of-magnetically-entrapped-dna-sequences-from-complex-samples-by-multiplexed-enzymatic-labelling-application-to-a-transgenic-food-feed-quantitative-survey
#16
C L Manzanares-Palenzuela, J P Martín-Clemente, M J Lobo-Castañón, B López-Ruiz
Monitoring of genetically modified organisms in food and feed demands molecular techniques that deliver accurate quantitative results. Electrochemical DNA detection has been widely described in this field, yet most reports convey qualitative data and application in processed food and feed samples is limited. Herein, the applicability of an electrochemical multiplex assay for DNA quantification in complex samples is assessed. The method consists of the simultaneous magnetic entrapment via sandwich hybridisation of two DNA sequences (event-specific and taxon-specific) onto the surface of magnetic microparticles, followed by bienzymatic labelling...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107923/a-sensitive-and-rapid-uflc-apci-ms-ms-bioanalytical-method-for-quantification-of-endogenous-and-exogenous-vitamin-k1-isomers-in-human-plasma-development-validation-and-first-application-to-a-pharmacokinetic-study
#17
Nagaraj Kumar Nannapaneni, Sunil S Jalalpure, Rajendraprasad Muppavarapu, Sunil Kumar Sirigiri
Due to lack of suitable bioanalytical methods in previous literature, for simultaneous estimation of Vitamin K1 isomers, in compliance with the current regulatory expectation, we aimed to develop a sensitive and rapid method with UFLC-APCI-MS/MS (ultrafast liquid chromatography - tandem mass spectrometry) using human plasma. A simple and cost effective procedure was implemented with the combination of protein precipitation and liquid extraction, to isolate the targets from plasma sample, while achieving an insignificant matrix effects and high recovery (≥88...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107833/water-can-be-a-probe-for-sensing-glucose-in-aqueous-solutions-by-temperature-dependent-near-infrared-spectra
#18
Xiaoyu Cui, Xiuwei Liu, Xiaoming Yu, Wensheng Cai, Xueguang Shao
Near infrared (NIR) spectra are sensitive to the variation on water structure caused by perturbations, such as temperature and additives. In this work, water was applied as a probe to detect glucose in aqueous glucose solutions and human serum samples. Spectral changes of water were captured from the temperature dependent NIR spectra using multilevel simultaneous component analysis (MSCA). The first and second level model were established to describe the quantitative spectra-temperature relationship (QSTR) and the quantitative spectra-concentration relationship (QSCR), i...
March 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28107829/high-throughput-online-solid-phase-extraction-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-method-for-polyfluoroalkyl-phosphate-esters-perfluoroalkyl-phosphonates-and-other-perfluoroalkyl-substances-in-human-serum-plasma-and-whole-blood
#19
Somrutai Poothong, Elsa Lundanes, Cathrine Thomsen, Line Småstuen Haug
A rapid, sensitive and reliable method was developed for the determination of a broad range of poly- and perfluoroalkyl substances (PFASs) in various blood matrices (serum, plasma, and whole blood), and uses only 50 μL of sample material. The method consists of a rapid protein precipitation by methanol followed by high throughput online solid phase extraction (SPE), ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), and negative electrospray ionization detection...
March 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28107701/simultaneous-determination-of-amantadine-rimantadine-and-memantine-in-processed-products-chicken-tissues-and-eggs-by-liquid-chromatography-with-tandem-mass-spectrometry
#20
Yumi Tsuruoka, Takayuki Nakajima, Maki Kanda, Hiroshi Hayashi, Yoko Matsushima, Souichi Yoshikawa, Marie Nagata, Hiroshi Koike, Chieko Nagano, Kotaro Sekimura, Tsuneo Hashimoto, Ichiro Takano, Tetsuya Shindo
A simultaneous determination of amantadine, rimantadine, and memantine in processed products (deep-fried chicken, fried chicken, fried quail egg, and grilled chicken) with liquid chromatography tandem mass spectrometry (LC-MS/MS) was developed. This new method was also applicable for chicken tissue (muscle, liver, and gizzard) and eggs. The chromatographic separation was performed on a Kinetex(®) XB-C18 core-shell technology column using a mobile phase of acetonitrile and 0.1% formic acid in a 10mmol/L ammonium formate solution, resulting in the complete separation of isomers (rimantadine and memantine) and any other obstructive peaks from the sample matrices...
January 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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