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https://www.readbyqxmd.com/read/28339765/stem-moir%C3%A3-analysis-for-2d-strain-measurements
#1
Akimitsu Ishizuka, Martin Hytch, Kazuo Ishizuka
A moiré pattern is created in a scanning transmission electron microscope (STEM) when the scan step is close to a crystalline periodicity. Usually, fringes are visible in only one direction, corresponding to a single set of lattice planes, but fringes can be formed in two directions or more. Using an accurate independent calibration, the strains in silicon devices have been determined from the spacing and orientation of one-directional STEM moiré fringes. In this report, we first discuss the origin of the STEM moiré, and then we show how an accurate calibration of the scan step can be obtained from the STEM moiré pattern itself, providing that we know initially only an approximate scan step and the planar spacing...
February 24, 2017: Microscopy
https://www.readbyqxmd.com/read/28339555/an-item-bank-for-abuse-of-prescription-pain-medication-from-the-patient-reported-outcomes-measurement-information-system-promis%C3%A2
#2
Paul A Pilkonis, Lan Yu, Nathan E Dodds, Kelly L Johnston, Suzanne M Lawrence, Thomas F Hilton, Dennis C Daley, Ashwin A Patkar, Dennis McCarty
Objective.:  There is a need to monitor patients receiving prescription opioids to detect possible signs of abuse. To address this need, we developed and calibrated an item bank for severity of abuse of prescription pain medication as part of the Patient-Reported Outcomes Measurement Information System (PROMIS ® ). Methods.:  Comprehensive literature searches yielded an initial bank of 5,310 items relevant to substance use and abuse, including abuse of prescription pain medication, from over 80 unique instruments...
October 8, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28338965/burrowers-from-the-past-mitochondrial-signatures-of-ordovician-bivalve-infaunalization
#3
Federico Plazzi, Guglielmo Puccio, Marco Passamonti
Bivalves and gastropods are the two largest classes of extant molluscs. Despite sharing a huge number of features, they do not share a key ecological one: gastropods are essentially epibenthic, while most bivalves are infaunal. However, this is not the ancestral bivalve condition; Cambrian forms were surface crawlers and only during the Ordovician a fundamental infaunalization process took place, leading to bivalves as we currently know them. This major ecological shift is linked to the exposure to a different redox environoments (hypoxic or anoxic) and with the Lower Devonian oxygenation event...
March 9, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28338929/performance-tests-of-active-personal-dosemeter-developed-by-%C3%A3-nrtc-nel
#4
Dogan Yasar, Enis Kapdan, Muharrem Korkmaz
The Active personal dosemeter (APD) developed by Çekmece Nuclear Research and Training Center/Nuclear Electronic Laboratory (ÇNRTC/NEL) was calibrated at the reference radiation quality (137Cs). The performance tests were carried out with 137Cs, 60Co and X-ray beam qualities in compliance with the standards of International Organization for Standardization ISO4037-1,3 and The International Electrotechnical Commission, IEC61526:2010. Response of the personal dose equivalent was observed to be within the range from -7...
March 1, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28338842/personal-exposimeter-for-radiation-assessment-in-real-environments-in-the-60-ghz-band
#5
Reza Aminzadeh, Arno Thielens, Haolin Li, Carole Leduc, Maxim Zhadobov, Guy Torfs, Johan Bauwelinck, Luc Martens, Wout Joseph
For the first time, a personal exposimeter (PEX) for 60 GHz radiation measurements is presented. The PEX is designed based on numerical simulations and both on-body and on-phantom calibration measurements to determine the antenna aperture and measurement uncertainty of the PEX. The measurement uncertainty of the PEX is quantified in terms of 50 and 95% prediction intervals of its response. A PEX consisting of three nodes (antennas) with VHH (vertical-horizontal-horizontal) polarization results in a 95% prediction interval of 6...
February 25, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28338642/determination-of-ultra-trace-rhodium-in-water-samples-by-graphite-furnace-atomic-absorption-spectrometry-after-cloud-point-extraction-using-2-5-iodo-2-pyridylazo-5-dimethylaminoaniline-as-a-chelating-agent
#6
Quan Han, Yanyan Huo, Jiangyan Wu, Yaping He, Xiaohui Yang, Longhu Yang
A highly sensitive method based on cloud point extraction (CPE) separation/preconcentration and graphite furnace atomic absorption spectrometry (GFAAS) detection has been developed for the determination of ultra-trace amounts of rhodium in water samples. A new reagent, 2-(5-iodo-2-pyridylazo)-5-dimethylaminoaniline (5-I-PADMA), was used as the chelating agent and the nonionic surfactant TritonX-114 was chosen as extractant. In a HAc-NaAc buffer solution at pH 5.5, Rh(III) reacts with 5-I-PADMA to form a stable chelate by heating in a boiling water bath for 10 min...
March 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28338490/small-volume-injections-evaluation-of-volume-administration-deviation-from-intended-injection-volumes
#7
Matthew K Muffly, Michael I Chen, Rebecca E Claure, David R Drover, Bradley Efron, William L Fitch, Gregory B Hammer
BACKGROUND: In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses...
March 23, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28338135/detection-of-chemical-warfare-agent-simulants-and-hydrolysis-products-in-biological-samples-by-paper-spray-mass-spectrometry
#8
Josiah McKenna, Elizabeth S Dhummakupt, Theresa Connell, Paul S Demond, Dennis B Miller, J Michael Nilles, Nicholas E Manicke, Trevor Glaros
Paper spray ionization coupled to a high resolution tandem mass spectrometer (a quadrupole orbitrap) was used to identify and quantitate chemical warfare agent (CWA) simulants and their hydrolysis products in blood and urine. Three CWA simulants, dimethyl methylphosphonate (DMMP), trimethyl phosphate (TMP), and diisopropyl methylphosphonate (DIMP), and their isotopically labeled standards were analyzed in human whole blood and urine. Calibration curves were generated and tested with continuing calibration verification standards...
March 24, 2017: Analyst
https://www.readbyqxmd.com/read/28337999/comparison-of-validation-and-application-on-various-cardiovascular-disease-mortality-risk-prediction-models-in-chinese-rural-population
#9
Changqing Sun, Fei Xu, Xiaotian Liu, Mingwang Fang, Hao Zhou, Yixiao Lian, Chen Xie, Nan Sun, Chongjian Wang
This research aims to assess application of different cardiovascular disease (CVD) mortality risk prediction models in Chinese rural population. Data was collected from a 6-year follow-up survey in rural area of Henan Province, China. 10338 participants aged 40 to 65 years were included. Baseline study was conducted between 2007 and 2008, and followed up from 2013 to 2014. Seven models: general Framingham risk score (general-FRS), simplified-FRS, Systematic Coronary Risk Evaluation for high (SCORE-high), SCORE-low, Chinese ischemic CVD (CN-ICVD), Pooled Cohort Risk Equation for white (PCE-white) and for African-American (PCE-AA) were assessed and recalibrated...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337676/logistic-proliferation-of-cells-in-scratch-assays-is-delayed
#10
Wang Jin, Esha T Shah, Catherine J Penington, Scott W McCue, Philip K Maini, Matthew J Simpson
Scratch assays are used to study how a population of cells re-colonises a vacant region on a two-dimensional substrate after a cell monolayer is scratched. These experiments are used in many applications including drug design for the treatment of cancer and chronic wounds. To provide insights into the mechanisms that drive scratch assays, solutions of continuum reaction-diffusion models have been calibrated to data from scratch assays. These models typically include a logistic source term to describe carrying capacity-limited proliferation; however, the choice of using a logistic source term is often made without examining whether it is valid...
March 23, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28336787/probabilistic-divergence-time-estimation-without-branch-lengths-dating-the-origins-of-dinosaurs-avian-flight-and-crown-birds
#11
G T Lloyd, D W Bapst, M Friedman, K E Davis
Branch lengths-measured in character changes-are an essential requirement of clock-based divergence estimation, regardless of whether the fossil calibrations used represent nodes or tips. However, a separate set of divergence time approaches are typically used to date palaeontological trees, which may lack such branch lengths. Among these methods, sophisticated probabilistic approaches have recently emerged, in contrast with simpler algorithms relying on minimum node ages. Here, using a novel phylogenetic hypothesis for Mesozoic dinosaurs, we apply two such approaches to estimate divergence times for: (i) Dinosauria, (ii) Avialae (the earliest birds) and (iii) Neornithes (crown birds)...
November 2016: Biology Letters
https://www.readbyqxmd.com/read/28336740/towards-personalised-intra-arterial-treatment-of-patients-with-acute-ischaemic-stroke-a-study-protocol-for-development-and-validation-of-a-clinical-decision-aid
#12
Maxim J H L Mulder, Esmee Venema, Bob Roozenbeek, Joseph P Broderick, Sharon D Yeatts, Pooja Khatri, Olvert A Berkhemer, Yvo B W E M Roos, Charles B L M Majoie, Robert J van Oostenbrugge, Wim H van Zwam, Aad van der Lugt, Ewout W Steyerberg, Diederik W J Dippel, Hester F Lingsma
INTRODUCTION: Overall, intra-arterial treatment (IAT) proved to be beneficial in patients with acute ischaemic stroke due to a proximal occlusion in the anterior circulation. However, heterogeneity in treatment benefit may be relevant for personalised clinical decision-making. Our aim is to improve selection of patients for IAT by predicting individual treatment benefit or harm. METHODS AND ANALYSIS: We will use data collected in the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN) trial to analyse the effect of baseline characteristics on outcome and treatment effect...
March 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28335999/model-for-porosity-changes-occurring-during-ultrasound-enhanced-transcorneal-drug-delivery
#13
Prasanna Hariharan, Marjan Nabili, Allan Guan, Vesna Zderic, Matthew Myers
Ultrasound-enhanced drug delivery through the cornea has considerable therapeutic potential. However, our understanding of how ultrasound enhances drug transport is poor, as is our ability to predict the increased level of transport for given ultrasound parameters. Described here is a computational model for quantifying changes in corneal porosity during ultrasound exposure. The model is calibrated through experiments involving sodium fluorescein transport through rabbit cornea. Validation was performed using nylon filters, for which the properties are known...
March 20, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28335981/external-cavity-quantum-cascade-laser-ec-qcl-spectroscopy-for-protein-analysis-in-bovine-milk
#14
Julia Kuligowski, Andreas Schwaighofer, Mirta Raquel Alcaráz, Guillermo Quintás, Helmut Mayer, Máximo Vento, Bernhard Lendl
The analytical determination of bovine milk proteins is important in food and non-food industrial applications and yet, rather labour-intensive wet-chemical, low-throughput methods have been employed since decades. This work proposes the use of external cavity-quantum cascade laser (EC-QCL) spectroscopy for the simultaneous quantification of the most abundant bovine milk proteins and the total protein content based on the chemical information contained in mid-infrared (IR) spectral features of the amide I band...
April 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28335722/generalizing-cell-segmentation-and-quantification
#15
Zhenzhou Wang, Haixing Li
BACKGROUND: In recent years, the microscopy technology for imaging cells has developed greatly and rapidly. The accompanying requirements for automatic segmentation and quantification of the imaged cells are becoming more and more. After studied widely in both scientific research and industrial applications for many decades, cell segmentation has achieved great progress, especially in segmenting some specific types of cells, e.g. muscle cells. However, it lacks a framework to address the cell segmentation problems generally...
March 23, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28335612/thrombin-generation-in-patients-with-suspected-venous-thromboembolism
#16
Fredrik Wexels, Ola E Dahl, Are H Pripp, Ingebjørg Seljeflot
Increasing number of patients with clinically suspected venous thromboembolism is referred to radiological departments for definitive diagnosis. A simple assay to exclude the diagnosis and avoid radiological examinations is needed. We have reported correlations between D-dimer and prothrombin fragment 1 + 2 measured in plasma and urine. To further develop an analysis based on urine, more understanding of thrombin generation in these patients is needed. The aim of this study was to compare ex vivo thrombin generation with in vivo markers in plasma and urine in patients with and without venous thromboembolism...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28335574/proof-of-concept-development-of-snow-liquid-water-content-profiler-using-cs650-reflectometers-at-caribou-me-usa
#17
Carlos L Pérez Díaz, Jonathan Muñoz, Tarendra Lakhankar, Reza Khanbilvardi, Peter Romanov
The quantity of liquid water in the snowpack defines its wetness. The temporal evolution of snow wetness's plays a significant role in wet-snow avalanche prediction, meltwater release, and water availability estimations and assessments within a river basin. However, it remains a difficult task and a demanding issue to measure the snowpack's liquid water content (LWC) and its temporal evolution with conventional in situ techniques. We propose an approach based on the use of time-domain reflectometry (TDR) and CS650 soil water content reflectometers to measure the snowpack's LWC and temperature profiles...
March 21, 2017: Sensors
https://www.readbyqxmd.com/read/28335436/photonic-low-cost-micro-sensor-for-in-line-wear-particle-detection-in-flowing-lube-oils
#18
Jon Mabe, Joseba Zubia, Eneko Gorritxategi
The presence of microscopic particles in suspension in industrial fluids is often an early warning of latent or imminent failures in the equipment or processes where they are being used. This manuscript describes work undertaken to integrate different photonic principles with a micro- mechanical fluidic structure and an embedded processor to develop a fully autonomous wear debris sensor for in-line monitoring of industrial fluids. Lens-less microscopy, stroboscopic illumination, a CMOS imager and embedded machine vision technologies have been merged to develop a sensor solution that is able to detect and quantify the number and size of micrometric particles suspended in a continuous flow of a fluid...
March 14, 2017: Sensors
https://www.readbyqxmd.com/read/28335262/nanomaterials-for-tissue-engineering-in-dentistry
#19
REVIEW
Manila Chieruzzi, Stefano Pagano, Silvia Moretti, Roberto Pinna, Egle Milia, Luigi Torre, Stefano Eramo
The tissue engineering (TE) of dental oral tissue is facing significant changes in clinical treatments in dentistry. TE is based on a stem cell, signaling molecule, and scaffold triad that must be known and calibrated with attention to specific sectors in dentistry. This review article shows a summary of micro- and nanomorphological characteristics of dental tissues, of stem cells available in the oral region, of signaling molecules usable in TE, and of scaffolds available to guide partial or total reconstruction of hard, soft, periodontal, and bone tissues...
July 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335260/a-label-free-microelectrode-array-based-on-one-step-synthesis-of-chitosan-multi-walled-carbon-nanotube-thionine-for-ultrasensitive-detection-of-carcinoembryonic-antigen
#20
Huiren Xu, Yang Wang, Li Wang, Yilin Song, Jinping Luo, Xinxia Cai
Carcinoembryonic antigen (CEA) has been an extensively used tumor marker responsible for clinical early diagnosis of cervical carcinomas, and pancreatic, colorectal, gastric and lung cancer. Combined with micro-electro mechanical system (MEMS) technology, it is important to develop a novel immune microelectrode array (MEA) not only for rapid analysis of serum samples, but also for cell detection in vitro and in vivo. In this work, we depict a simple approach to modify chitosan-multi-walled carbon nanotubes-thionine (CS-MWCNTs-THI) hybrid film through one-step electrochemical deposition and the CS-MWCNTs-THI hybrid films are successfully employed to immobilize anti-CEA for fabricating simple, label-free, and highly sensitive electro-chemical immune MEAs...
July 11, 2016: Nanomaterials
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