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Tracheal tumor

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https://www.readbyqxmd.com/read/28734442/nonintubated-spontaneous-respiration-anesthesia-for-tracheal-glomus-tumor
#1
Jun Huang, Yuan Qiu, Lei Chen, Hui Liu, Qinglong Dong, Lixia Liang, Jiaxi He, Jianxing He, Hanzhang Chen
Previous tracheal surgeries were performed under tracheal and cross-field intubation. However, the intubation would lead to bleeding if the tumors were large or hemorrhagic. Moreover, the tracheal intubation might interfere the surgical vision and anastomosis during the reconstruction process. Therefore, we performed a tracheal tumor resection and reconstruction via nonintubated spontaneous anesthesia. We describe the feasibility and safety of tracheal surgeries via such anesthesia.
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28723308/percutaneous-trans-tracheal-endoscopic-approach-a-novel-technique-for-the-excision-of-benign-lesions-of-thoracic-trachea
#2
Suresh C Sharma, K Devaraja, Arvind Kairo, Rakesh Kumar
INTRODUCTION: Currently, neoplasms of the trachea and lower airway demand open transcervical approach with or without thoracotomy. We describe here a novel, minimally invasive approach for an intraluminal lesion of the thoracic trachea, called percutaneous trans-tracheal endoscopic approach (PTEA). Apart from obvious advantages over potentially morbid open procedures, this technique has certain peculiar benefits over rigid or flexible bronchoscopic approach. MATERIALS AND METHODS: A 43-year-old male patient had glomus tumor of thoracic trachea...
July 19, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28695809/diagnosis-and-clinical-analysis-of-primary-thyroid-lymphoma
#3
Yong Xie, Wenjing Liu, Yuewu Liu, Wenze Wang, Mengyi Wang, Hongfeng Liu, Xiaoyi Li, Weisheng Gao
Objective To summarize our experiences in the diagnosis and prognosis of different subtypes of primary thyroid lymphoma (PTL). Methods The clinical data of 27 PTL patients who were treated in our hospital from January 1998 to December 2014 were retrospectively analyzed. The pathological types of these patients included B cell lymphoma unclassifiable (BCLU) (n=5),mucosa-associated lymphiod tissue lymphoma (MALT) (n=9),diffuse large B cell lymphoma (DLBCL) (n=12),and T cell lymphoma (n=1). Results Of all these 27 cases,the most common clinical symptom was painless swelling of the neck (n=21,77...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28689797/pudilan-xiaoyan-oral-liquid-alleviates-lps-induced-respiratory-injury-through-decreasing-nitroxidative-stress-and-blocking-tlr4-activation-along-with-nf-%C3%AE-b-phosphorylation-in-mice
#4
Liang Feng, Nan Yang, Chao Li, Gang Tian, Jing Wang, Zi-Bo Dong, Xiao-Bin Jia, Liu-Qing Di
ETHNOPHARMACOLOGICAL RELEVANCE: Pudilan xiaoyan oral liquid (PDL), collected in Chinese Pharmacopoeia, has been used clinically for treating inflammatory diseases such as upper respiratory tract infection diseases. However, its potential anti-inflammation and the mechanism are still unclear. MATERIALS AND METHODS: lipopolysaccharide (LPS) was used to induce respiratory inflammation of mice by intratracheal administration. UPLC/MS was performed for components analysis of PDL...
July 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28681367/expandable-metallic-stent-for-endobronchial-metastasis-from-colorectal-cancer-reports-of-2-cases
#5
Tomoki Nakamura, Takayuki Tajima, Takashi Ogimi, Hiroshi Miyakita, Miho Nitta, Kazunori Myojin, Sakurako Tajiri, Ichiro Kobayashi, Takayuki Nishi, Sotaro Sadahiro, Hideo Shimada
In recent years, there have been many reports about the efficacy of stenting for central bronchial stenosis. When central bronchial stenosis is due to metastasis of a malignant tumor to the trachea and/or bronchi (endobronchial metastasis: EM), it is classified as "narrow EM" and "broad EM." [1] We managed two patients in whom bilateral stent placement was required for narrow and broad EM arising from colorectal cancer. Case 1: In September 2011, a 66-year-old man underwent low anterior resection for advanced colorectal cancer associated with unresectable liver metastasis...
July 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28665067/the-different-clinical-aspects-of-pediatric-primary-airway-tumors-in-the-larynx-trachea-and-bronchi
#6
Hyun Ju Cho, Jisun Yoon, Eun Lee, Yoon Se Lee, Sang Yoon Kim, Jong Lyel Roh, Dong Kwan Kim, Se Hoon Choi, Seung Il Park, Yong Hee Kim, Kyung Nam Koh, Ho Joon Im, Jong Jin Seo, Soo Jong Hong, Jinho Yu
Primary airway tumors are rare in children and no literature reviewed their characteristics each location. We evaluate the clinical characteristics and outcomes of Korean children with primary airway tumors, from the larynx to bronchi. A retrospective chart review of children with primary tumors of the larynx, trachea, and bronchi at Asan Medical Center from January 2000 to July 2016 was conducted. Nineteen children were diagnosed with primary airway tumors of the larynx (47.4%), trachea (10.5%), and bronchi (42...
August 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28659824/hypersensitivity-of-vagal-pulmonary-afferents-induced-by-tumor-necrosis-factor-alpha-in-mice
#7
Ruei-Lung Lin, Qihai Gu, Lu-Yuan Lee
Tumor necrosis factor alpha (TNFα), a pro-inflammatory cytokine, plays a significant role in the pathogenesis of allergic asthma. Inhalation of TNFα also induces airway hyperresponsiveness in healthy human subjects, and the underlying mechanism is not fully understood. A recent study reported that TNFα caused airway inflammation and a sustained elevation of pulmonary chemoreflex responses in mice, suggesting a possible involvement of heightened sensitivity of vagal pulmonary C-fibers. To investigate this possibility, the present study aimed to investigate the effect of a pretreatment with TNFα on the sensitivity of vagal pulmonary afferents in anesthetized mice...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28656580/potential-lung-carcinogenicity-induced-by-chronic-exposure-to-pm2-5-in-the-rat
#8
Xiaoli Hu, Qingzhao Li, Shifeng Shao, Qiang Zeng, Shoufang Jiang, Qi Wu, Chunyang Jiang
Exposure to fine particulate matter (PM2.5) may increase lung cancer risk, but the underlying mechanisms are poorly understood. This study explored the potential carcinogenicity in rat lung induced by chronic exposure to PM2.5. Adult male rats (200-220 g) were treated with PM2.5 (10 mg/kg body weight) by tracheal perfusion once per week for 1 year; the rats were killed, and expression of tumor markers (carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), squamous cell carcinoma antigen (SCCA)), cancer-related genes, and pathological changes were detected...
June 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28639955/endotracheal-leiomyoma-mimicking-malignancy-on-18f-fdg-pet-ct-in-a-patient-with-papillary-thyroid-carcinoma
#9
Jae Pil Hwang, Seung-Won Lee, Jeong Ja Kwak, Jung Mi Park
Endotracheal leiomyoma is a rare benign lesion, accounting for approximately 1% of tracheal tumors, and generally occurs in the lower respiratory tract. Because its growth causes airway obstruction symptom, surgical treatment is generally suggested after detection. We report a case with leiomyoma of the cervical endotracheal space showing intense FDG uptake on F-FDG PET/CT mimicking malignancy in a 79-year-old woman with papillary thyroid carcinoma.
June 20, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28627346/-study-on-rac1-mapk-erk-pathway-mediated-mechanism-and-role-in-rats-with-ventilator-induced-lung-injury
#10
Guanghua Tao, Linghui Pan, Ren Jing, Fei Lin, Huijun Dai, Wanyun Ge
OBJECTIVE: To investigate the role of Ras-related C3 botulinum toxin substrate 1/mitogen-activated protein kinase/extracellular signal-regulated kinase (Rac1/MAPK/ERK) signal pathway in rats with ventilator induced lung injury (VILI) and its mechanism. METHODS: Thirty Sprague-Dawley (SD) rats were randomly divided into spontaneous respiration group, normal tidal volume (VT) group and high VT group with 10 rats in each group. The rats in spontaneous respiration group were kept their spontaneous breathing...
March 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28620556/tracheal-chondrosarcoma-systematic-review-of-tumor-characteristics-diagnosis-and-treatment-outcomes-with-case-report
#11
Emily A Kutzner, Joshua S Park, Salman Zaheer, Jared C Inman
To our knowledge this is the first systematic review of tracheal chondrosarcoma treatment outcomes. Management insights are thoroughly discussed. Men constitute 93.8% of cases, and most of these occur in the distal trachea. The most common symptom, dyspnea, occurs in virtually all patients. Extratracheal extension had occurred in 78.6% of patients. Definitive treatment with tracheal resection showed no recurrences in 10 patients with mean follow-up of 3.1 years. Adjuvant radiotherapy may be utilized for improving local control when open complete resection cannot be performed, but only after endoscopic excision of gross tumor...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28620501/efficacy-of-lenvatinib-in-a-patient-with-anaplastic-thyroid-cancer
#12
Kazuyuki Oishi, Daisuke Takabatake, Yuichi Shibuya
We experienced a case of an 82-year-old woman who presented to our hospital with a 1-month history of dysphagia and dyspnea. Cervical contrast-enhanced computed tomography revealed diffuse thyroid neoplasms causing significant tracheal stenosis with tumors, particularly of the superior mediastinum, which were associated with an embolism of the brachiocephalic vein and suspected invasion to the bilateral common carotid arteries. Anaplastic thyroid cancer (ATC) was diagnosed by fine-needle aspiration; thus, emergency tracheostomy and gastrostomy were performed...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28616295/malignant-tracheal-necrosis-and-fistula-formation-following-palliative-chemoradiotherapy-a-case-report
#13
In Ae Kim, Hyeon Kang Koh, Sun Jong Kim, Kwang Ha Yoo, Kye Young Lee, Hee Joung Kim
Concurrent chemoradiotherapy is an essential treatment strategy for inoperable locally advanced non-small cell lung cancer (NSCLC). Although supportive care has improved, unexpected complications due to the disease or treatment can occur. Tracheomediastinal fistulas are very rare but can be a serious problem. Herein, we report a case of severe chondronecrosis of the distal trachea with formation of a fistula into a metastatic lymphadenopathy in a patient with stage IIIB NSCLC. The patient received external beam radiotherapy with a total dose of 35 Gy in 14 fractions, which was approximately half of the conventional therapeutic radiotherapy dose, along with concurrent cisplatin based chemotherapy...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28610883/the-validation-of-a-no-drain-policy-after-thoracoscopic-major-lung-resection
#14
Junichi Murakami, Kazuhiro Ueda, Toshiki Tanaka, Taiga Kobayashi, Yoshie Kunihiro, Kimikazu Hamano
BACKGROUND: The omission of postoperative chest tube drainage may contribute to early recovery after thoracoscopic major lung resection; however, a validation study is necessary before the dissemination of a selective drain policy. METHODS: A total of 162 patients who underwent thoracoscopic anatomical lung resection for lung tumors were enrolled in this study. Alveolar air leaks were sealed with a combination of bioabsorbable mesh and fibrin glue. The chest tube was removed just after the removal of the tracheal tube in selected patients in whom complete pneumostasis was obtained...
June 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28592026/-clinical-analysis-of-therapeutic-bronchoscopy-for-tracheal-neoplasm
#15
Y F Ding, L Chen, H D Huang, Y C Dong, X P Yao, Y Huang, Q Wang, W Zhang, Q Li, C Bai
Objective: To analyze the clinical features in adults with tracheal neoplasm and to evaluate the efficacy of interventional bronchoscopic treatment. Methods: We retrospectively analyzed the clinical features of 43 adults undergoing therapeutic bronchoscopy for tracheal neoplasm diagnosed in Changhai Hospital affiliated to the Second Military Medical University from January 2004 to July 2014.The degree of stenosis, the grade of dyspnea, and Karnofsky performance status scale were evaluated before and after the last procedure...
June 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28538020/incidence-and-risk-factors-of-hypoxemia-during-interventional-rigid-bronchoscopy-under-spontaneous-assisted-ventilation
#16
Saowapark Chumpathong, Jamsak Tscheikuna, Thanatporn Boonsombat, Saipin Muangman, Choopong Luansritisakul
BACKGROUND: Interventional rigid bronchoscopy for tracheobronchial stenosis can be performed under total intravenous anesthesia and spontaneous-assisted ventilation. Intraoperative hypoxemia can occur during this procedure, but the incidence and risk factors have not yet been determined. MATERIALS AND METHODS: Medical records of patients who underwent rigid bronchoscopy for the treatment of tracheobronchial stenosis under total intravenous anesthesia and spontaneous-assisted ventilation during the study period from January 2011 to December 2012 were retrospectively reviewed...
May 19, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28522278/a-large-french-multicenter-retrospective-series-of-t1-t2n0-vocal-cords-carcinomas-treated-with-exclusive-irradiation
#17
MULTICENTER STUDY
A Robert, Y Pointreau, G Janoray, É Bardet, M Fesneau, P Garaud, S Chapet, C Lafond, O Dupuis, G Calais
PURPOSE: The main objective of this study was to evaluate the 5-year efficacy of exclusive laryngeal radiotherapy without node prophylactic irradiation for localized cancers of the vocal cords. PATIENTS AND METHODS: We retrospectively reviewed charts from 258 patients with T1-T2N0 glottic carcinoma irradiated from April 1987 to March 2015 in four France western centers, including pretreated patients. Toxicity was analyzed according to CTCAE v4.0 classification. RESULTS: The median follow-up was 50 months...
June 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28458792/tracheal-glomus-tumor-a-case-report-and-review-of-the-literature
#18
Ollin Venegas, Andrew Newton, Norge Vergara, Sunil Singhal, Jarrod D Predina
Glomus tumors are rare neoplasms that typically occur within the dermis or subcutis of the subungual space. Primary glomus tumors of the thorax are exceedingly uncommon, thus standard-of-care management is lacking. In this report we describe the management of a patient presenting with a symptomatic glomus tumor of the posterior trachea, and provide a comprehensive review including all documented tracheal glomus tumor reports.
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28449512/primary-tracheal-schwannoma-treated-by-surgical-resection-a-case-report
#19
Ding-Pei Han, Jie Xiang, Zhi-Qiu Ye, Dan-Nong He, Xiao-Chun Fei, Chao-Fu Wang, Jia-Ming Che, Jun-Biao Hang, He-Cheng Li
The rarity and non-specific symptoms of benign primary tracheal tumors always leaded to misdiagnosis and delayed treatment, and also undefined the optimal treatment. In this case, a 45-year-old woman had a history of progressive shortness of breath and dry cough for several years, CT scan revealed an intra-luminal tracheal mass invaded the left side of tracheal wall. After being located by bronchoscope preoperatively, the tumor was removed by surgical resection. The tumor was 1.5 cm in diameter with intact capsule...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28407313/prognosis-of-primary-tracheal-tumor-a-population-based-analysis
#20
Jiaxi He, Jianfei Shen, Jun Huang, Chenyang Dai, Wenhua Liang, Minhua Ye, Min Kong, Baofu Chen, Chengchu Zhu, Jianxing He
BACKGROUND: To elucidate the survival outcomes of tracheal tumors and to propose the potential stage of tracheal tumors. METHOD: All cases of primary tracheal malignant tumors were extracted from the Surveillance, Epidemiology, and End Results database (SEER) during 1973-2013. The overall survival was calculated using Kaplan-Meier method. Cox regression was utilized to identify the prognostic factors. RESULT: A total of 287 cases were finally included...
June 2017: Journal of Surgical Oncology
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