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Sickness Absence

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https://www.readbyqxmd.com/read/29315578/hcn4-pacemaker-channels-attenuate-the-parasympathetic-response-and-stabilize-the-spontaneous-firing-of-sinoatrial-node
#1
Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano
The heart rate is dynamically controlled by the sympathetic and parasympathetic nervous systems that regulate the sinoatrial node (SAN). HCN4 pacemaker channels are well-known causative molecule of congenital sick sinus syndrome. Although HCN4 channels are activated by cAMP, the sympathetic response of SAN was preserved in the patients carrying loss-of-function mutations of HCN4 gene. In order to clarify the contribution of HCN4 channels in the autonomic regulation of SAN, we developed novel gain-of-function mutant mice in which expression level of HCN4 channels could be reversibly changed from zero to ∼3 times of that in wild type mice, using tetracycline trans-activator and tetracycline responsive element...
January 9, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29300819/labour-market-segregation-and-gender-differences-in-sickness-absence-trends-in-2005-2013-in-finland
#2
Taina Leinonen, Eira Viikari-Juntura, Kirsti Husgafvel-Pursiainen, Lauri J Virta, Mikko Laaksonen, Ilona Autti-Rämö, Svetlana Solovieva
Objectives: Women have higher sickness absence rate than men, but less is known of changes in this difference over time. We examined gender differences in sickness absence trends focusing on gender segregation in the labour market. Methods: We used large nationwide register data on Finnish wage earners aged 25-59 and generalized estimation equations based on repeated logistic regression to estimate the annual risk of sickness absence lasting at least 2 weeks. Results: Between 2005 and 2013, the age-adjusted proportion (%) of employees with all-cause sickness absence decreased from the initial levels of 10...
December 29, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29290454/-teacher-sick-leave-prevalence-duration-reasons-and-covariates
#3
M-N Vercambre-Jacquot, F Gilbert, N Billaudeau
BACKGROUND: Absences from work have considerable social and economic impact. In the education sector, the phenomenon is particularly worrying since teacher sick leave has an impact on the overall performance of the education system. Yet, available data are scarce. METHODS: In April-June 2013, 2653 teachers responded to a population-based postal survey on their quality of life (enquête Qualité de vie des enseignants, MGEN Foundation/Ministry of education, response rate 53 %)...
December 28, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29286513/influence-of-polymorphic-variants-of-the-slc6a4-gene-on-the-frequency-of-detection-of-depressive-states-in-the-group-of-the-clean-up-workers-of-consequences-of-chornobyl-accident-in-the-remote-period-after-the-chornobyl-catastrophe
#4
I V Abramenko, N I Bilous, S A Chumak, K M Loganovsky
Mental disorders of the victims are one of the important medical consequences of the Chornobyl accident. It is also known that in the implementation of the pathogenesis of depressive states a significant role belongs to the sero tonin transporter gene (SLC6A4). OBJECTIVE: To determine the effect of polymorphic variants of the SLC6A4 gene on the frequency of detection of depression in a group of clean up workers in the remote period after the Chornobyl catastrophe. METHODS: The study was conducted in a group of 59 victims of the Chornobyl NPP accident, divided into two groups (without depression and with depressive symptoms)...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29282116/sickness-absence-among-municipal-workers-in-a-brazilian-municipality-a-secondary-data-analysis
#5
Ana Lucia M Leao, Anadergh Barbosa-Branco, Marília D Turchi, Ivan A Steenstra, Donald C Cole
BACKGROUND: Sickness absence, work disability associated with illness or injury, is a major public health problem worldwide. Some studies have investigated determinants of sickness absence among workers with shorter job tenure, but have only focused on certain diagnostic groups. Although it is well established that job tenure has an inverse relationship with work injury rate, less is known about its association with sickness absence for other disorders. Therefore, this study aimed to investigate the risk factors for incidence and duration of sickness absence according to diagnosis over a 7-year period...
December 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29282110/the-joint-associations-of-smoking-and-obesity-with-subsequent-short-and-long-sickness-absence-a-five-year-follow-up-study-with-register-linkage
#6
Eira Roos, Tea Lallukka, Eero Lahelma, Ossi Rahkonen
BACKGROUND: Both smoking and obesity are separately associated with sickness absence. Unhealthy lifestyle habits and health conditions may occur concurrently yet studies focusing on their joint association are few. This study examined the joint associations of smoking and obesity with sickness absence (SA). METHODS: A mail survey among employees of the City of Helsinki, Finland, during 2000-2002 included data on obesity, smoking and covariates (N = 8960, response rate 67%, 80% women)...
December 28, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29274274/identifying-return-to-work-trajectories-using-sequence-analysis-in-a-cohort-of-workers-with-work-related-musculoskeletal-disorders
#7
Christopher McLeod, Eline Reiff, Esther Maas, Ute Bültmann
Objectives This study aimed to identify return-to-work (RTW) trajectories among workers with work-related musculoskeletal disorders (MSD) and examine the associations between different MSD and these RTW trajectories. Methods We used administrative workers' compensation data to identify accepted MSD lost-time claims with an injury date between 2010-2012 in British Columbia, Canada. Cox regression analyses were used to investigate differences in time to RTW between MSD. Validated day-to-day calendar measures of four RTW states (sickness absence, modified RTW, RTW, and non-RTW) were grouped into RTW trajectories spanning a one-year period using sequence analysis...
December 23, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29249738/factors-contributing-to-the-self-reported-prevalence-of-multiple-chemical-sensitivity-in-public-facility-workers-and-the-general-population-of-korea
#8
Yong Heo, Sang-Hoon Kim, Seok-Ki Lee, Hyoung-Ah Kim
Multiple chemical sensitivity (MCS), an acquired disorder with multiple recurrent symptoms, has been studied for its association with diverse environmental factors. The present study investigated the factors associated with the self-reported prevalence of MCS in public facility workers and the general population in Korea. The Quick Environmental Exposure Sensitivity Inventory (QEESI) questionnaire was obtained from public facility workers (N=530) and the general population (N=500) to determine the prevalence of MCS and the degree of its risk...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/29246257/comparing-multidisciplinary-and-brief-intervention-in-employees-with-different-job-relations-on-sick-leave-due-to-low-back-pain-protocol-of-a-randomised-controlled-trial
#9
Pernille Pedersen, Claus Vinther Nielsen, Morten Hovgaard Andersen, Vivian Langagergaard, Anders Boes, Ole Kudsk Jensen, Chris Jensen, Merete Labriola
BACKGROUND: Low back pain (LBP) is a common problem that affects the lives of many individuals and is a frequent cause of sickness absence. To help this group of individuals resume work, several interventions have been studied. However, not all individuals may profit from the same intervention and the effect of a given intervention on return to work (RTW) may depend on their work situation. The aim of this study is to evaluate whether employees on sick leave due to LBP and with poor job relations will benefit more from a multidisciplinary intervention, while patients with strong job relations will benefit more from a brief intervention...
December 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29240739/office-design-and-health-a-systematic-review
#10
Ann Richardson, John Potter, Margaret Paterson, Thomas Harding, Gaye Tyler-Merrick, Ray Kirk, Kate Reid, Jane McChesney
AIM: To carry out a systematic review of recent research into the effects of workplace design, comparing individual with shared workspaces, on the health of employees. METHODS: The research question was "Does workplace design (specifically individual offices compared with shared workspaces) affect the health of workers?" A literature search limited to articles published between 2000 and 2017 was undertaken. A systematic review was carried out, and the findings of the reviewed studies grouped into themes according to the primary outcomes measured in the studies...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29236884/prevalence-of-common-mental-disorders-among-sugarcane-workers
#11
Polyana Felipe Ferreira da Costa, Solange Laurentino Dos Santos, Marcelo Saturnino da Silva, Idê Gomes Dantas Gurgel
OBJECTIVE: To estimate the prevalence of common mental disorders and to analyze the associated factors in migrant and sugarcane workers. METHODS: This is a cross-sectional study carried out with 110 workers. Common mental disorders were evaluated using the Self-Reporting Questionnaire (SRQ-20), and sociodemographic, occupational, and lifestyle variables were studied. The CAGE questionnaire was used to detect the abuse of alcoholic beverages. RESULTS: The prevalence of common mental disorders affected 40% of the workers and the association showed statistical significance for the positive result of the CAGE test, sickness, absence from work, and medical care during the harvest period...
December 11, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29234955/predictors-of-return-to-work-6-months-after-the-end-of-treatment-in-patients-with-common-mental-disorders-a-cohort-study
#12
Mattias Victor, Bjørn Lau, Torleif Ruud
Purpose Common mental disorders (CMDs) account for a large portion of sickness absence. Even after attending return to work (RTW) interventions, many patients with a CMD remain on sick leave. To identify people at risk of long-term work disability, more needs to be known about factors that predict RTW after treatment. Methods This was a prospective cohort study that followed 106 former patients at an RTW outpatient clinic for CMDs for 6 months after the end of treatment. Changes in work participation and mental health status between the end of treatment and the 6-month follow-up were analysed...
December 12, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/29234482/roads-to-health-in-developing-countries-understanding-the-intersection-of-culture-and-healing
#13
REVIEW
S Ibeneme, G Eni, A Ezuma, G Fortwengel
Background: The most important attribute to which all human beings aspire is good health because it enables us to undertake different forms of activities of daily living. The emergence of scientific knowledge in Western societies has enabled scientists to explore and define several parameters of health by drawing boundaries around factors that are known to influence the attainment of good health. For example, the World Health Organization defined health by taking physical and psychological factors into consideration...
2017: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/29225216/depressive-symptoms-and-risk-of-absence-among-workers-in-a-manufacturing-company-a-12-month-follow-up-study
#14
Dirga Kumar Lamichhane, Yong Seok Heo, Hwan Cheol Kim
Depression is a leading cause of reduced work ability and absence due to sickness. The objective of this study was to investigate how depressive symptoms are prospectively associated with subsequent absence, whether caused by illness or accidents, among manufacturing workers. This prospective study was conducted on 2,349 male and female employees that underwent a regular health examination at a university hospital. Depressive symptoms were measured at baseline using the Center for Epidemiologic Studies Depression (CES-D) Scale...
December 8, 2017: Industrial Health
https://www.readbyqxmd.com/read/29224640/return-to-the-workforce-following-infective-endocarditis-a-nationwide-cohort-study
#15
MULTICENTER STUDY
Jawad H Butt, Kristian Kragholm, Michael Dalager-Pedersen, Rasmus Rørth, Søren L Kristensen, Mavish S Chaudry, Nana Valeur, Lauge Østergaard, Christian Torp-Pedersen, Gunnar H Gislason, Lars Køber, Emil L Fosbøl
BACKGROUND: The ability to return to work after infective endocarditis (IE) holds important socioeconomic consequences for both patients and society, yet data on this issue are sparse. We examined return to the workforce and associated factors in IE patients of working age. METHODS: Using Danish nationwide registries, we identified 1,065 patients aged 18-60 years with a first-time diagnosis of IE (1996-2013) who were part of the workforce prior to admission and alive at discharge...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29221477/trajectories-and-characteristics-of-functional-impairment-before-and-after-suicide-attempt-in-young-adults-a-nationwide-register-based-cohort-study
#16
Mo Wang, Magnus Helgesson, Syed Rahman, Thomas Niederkrotenthaler, Ellenor Mittendorfer-Rutz
BACKGROUND: Despite high rates of youth suicide attempt, little is known about patterns of functional impairment in terms of sickness absence and disability pension (SA/DP) before and after an attempt. The aim was to identify SA/DP trajectories among young adults with or without suicide attempt and to describe associations of socio-demographic and clinical factors with such trajectories. METHODS: This is a population-based cohort study of 5385 individuals aged 25-40 years with a first suicide attempt during 2007-2009...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29216856/interactional-justice-at-work-is-related-to-sickness-absence-a-study-using-repeated-measures-in-the-swedish-working-population
#17
Constanze Leineweber, Claudia Bernhard-Oettel, Paraskevi Peristera, Constanze Eib, Anna Nyberg, Hugo Westerlund
BACKGROUND: Research has shown that perceived unfairness contributes to higher rates of sickness absence. While shorter, but more frequent periods of sickness absence might be a possibility for the individual to get relief from high strain, long-term sickness absence might be a sign of more serious health problems. The Uncertainty Management Model suggests that justice is particularly important in times of uncertainty, e.g. perceived job insecurity. The present study investigated the association between interpersonal and informational justice at work with long and frequent sickness absence respectively, under conditions of job insecurity...
December 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29212430/work-ability-score-and-future-work-ability-as-predictors-of-register-based-disability-pension-and-long-term-sickness-absence-a-three-year-follow-up-study
#18
Ulla Kinnunen, Jouko Nätti
AIMS: We investigated two single items of the Work Ability Index - work ability score, and future work ability - as predictors of register-based disability pension and long-term sickness absence over a three-year follow-up. METHODS: Survey responses of 11,131 Finnish employees were linked to pension and long-term (more than 10 days) sickness absence register data by Statistics Finland. Work ability score was divided into poor (0-5), moderate (6-7) and good/excellent (8-10) and future work ability into poor (1-2) and good (3) work ability at baseline...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29212387/employee-experience-of-workplace-supervisor-contact-and-support-during-long-term-sickness-absence
#19
Nicholas J Buys, John Selander, Jing Sun
PURPOSE: Workplace support is an important factor in promoting successful return to work. The purpose of this article is to examine relationships between supervisor contact, perceived workplace support and demographic variables among employees on long-term sickness absence. MATERIALS AND METHOD: Data were collected from 204 public employees at a municipality in Sweden who had been on long term sickness absence (60 days or more) using a 23 question survey instrument that collected information on demographic variables, supervisor contact and perceived workplace support...
December 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29210635/potential-drug-targets-in-the-pentose-phosphate-pathway-of-trypanosomatids
#20
Ines Loureiro, Joana Faria, Nuno Santarem, Terry K Smith, Joana Tavares, Anabela Cordeiro-da-Silva
The trypanosomatids, Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp, are causative agents of important human diseases such African sleeping sickness, Chagas' disease and Leishmaniasis, respectively. The high impact of these diseases on human health and economy worldwide, the unsatisfactory available chemotherapeutic options and the absence of human effective vaccines, strongly justifies the search for new drugs. The pentose phosphate pathway has been proposed to be a viable strategy to defeat several infectious diseases, including those from trypanosomatids, as it includes an oxidative branch, important in the maintenance of cell redox homeostasis, and a non-oxidative branch in which ribose 5-phosphate and erythrose 4-phosphate, precursors of nucleic acids and aromatic amino acids, are produced...
December 5, 2017: Current Medicinal Chemistry
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