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weight loss surgery, bariatric, roux-en-y, sleeve

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https://www.readbyqxmd.com/read/29770924/roux-en-y-gastric-bypass-surgery-induced-weight-loss-and-metabolic-improvements-are-similar-in-tgr5-deficient-and-wildtype-mice
#1
Zheng Hao, R Leigh Townsend, Michael B Mumphrey, Thomas W Gettys, Sangho Yu, Heike Münzberg, Christopher D Morrison, Hans-Rudolf Berthoud
BACKGROUND AND PURPOSE: Roux-en-Y gastric bypass surgery (RYGB) remains one of the most effective treatments for obesity and type 2 diabetes. Despite this, the mechanisms through which it acts are still not well understood. Bile acid signaling through the transmembrane G-protein-coupled receptor TGR5 has been shown to have significant effects on metabolism and has recently been reported to be necessary for the full effects of vertical sleeve gastrectomy (VSG), a bariatric surgery with similar effects to RYGB...
May 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29754264/one-year-impact-of-bariatric-surgery-on-serum-anti-mullerian-hormone-levels-in-severely-obese-women
#2
Clara Vincentelli, Marie Maraninchi, René Valéro, Sophie Béliard, Flavia Maurice, Olivier Emungania, Bruno Berthet, Elise Lombard, Anne Dutour, Bénédicte Gaborit, Blandine Courbiere
INTRODUCTION: Although bariatric surgery seems to increase spontaneous fertility by improving ovulatory function in young women, its impact on ovarian reserve remains largely unknown. OBJECTIVE: To evaluate changes in serum anti-Mullerian hormone (AMH) levels in reproductive-age severely obese women after bariatric surgery (BS). METHODS: AMH levels were measured retrospectively in 39 women (mean age 34.6 ± 1.1 years, range 18-45) that underwent a sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) at baseline, and 6 and 12 months after BS...
May 12, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29730732/mechanisms-underlying-the-weight-loss-effects-of-rygb-and-sg-similar-yet-different
#3
REVIEW
A Pucci, R L Batterham
The worldwide obesity epidemic continues unabated, adversely impacting upon global health and economies. People with severe obesity suffer the greatest adverse health consequences with reduced life expectancy. Currently, bariatric surgery is the most effective treatment for people with severe obesity, resulting in marked sustained weight loss, improved obesity-associated comorbidities and reduced mortality. Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), the most common bariatric procedures undertaken globally, engender weight loss and metabolic improvements by mechanisms other than restriction and malabsorption...
May 5, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29724616/a-landscape-of-bariatric-surgery-in-canada-for-the-treatment-of-obesity-type-2-diabetes-and-other-comorbidities-in-adults
#4
REVIEW
Mehran Anvari, Rodrigo Lemus, Ruth Breau
Obesity has escalated worldwide and in Canada. Many chronic conditions, including type 2 diabetes, are directly correlated with obesity, and although the benefits and effectiveness of bariatric surgery have been proven in terms of sustained weight loss and improving comorbidities, the procedure is underaccessed and underutilized in Canada. We explored the complex landscape of bariatric surgery in Canada, reviewing the current state and focusing on the volume of procedures nationwide and at the provincial level, the type of surgical procedures performed, their outcomes and their associated complications...
December 12, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29722910/glycemic-management-in-the-bariatric-surgery-population-a-review-of-the-literature
#5
Meredith L Howard, Taylor D Steuber, Sarah A Nisly
Obesity is a worldwide epidemic often complicated by multiple comorbidities, including type 2 diabetes mellitus (T2DM). Bariatric surgery is an increasingly common and effective weight loss strategy for obese patients that may result in resolution of metabolic related disease states, such as T2DM. Although bariatric surgery has many positive outcomes for patients, dietary and pathophysiologic changes can create difficult to control blood glucose, especially in the immediate perioperative setting. Depending on oral antidiabetic agent and insulin needs preoperatively, many patients require cessation of oral agents and reduction or cessation of insulin...
May 3, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29684298/the-efficacy-of-selected-bariatric-surgery-methods-on-lipid-and-glucose-metabolism-a-retrospective-12-month-study
#6
Marek Bužga, Petra Marešová, Karin Petřeková, Pavol Holéczy, Kamil Kuča
OBJECTIVE: Approximately 25% of the Czech population is currently obese. Obesity rates are expected to increase in the future. Obesity not only raises the risk of health complications for individuals, but increasing rates also represent a significant and steadily growing economic burden for healthcare systems and society as a whole. The aim of this study was to evaluate the therapeutic efficacy of three methods of bariatric surgery: laparoscopic greater curve plication (LGCP), laparoscopic sleeve gastrectomy (LSG), and Roux-en-Y gastric bypass (RYBG) in patients with type 2 diabetes mellitus (DM)...
March 2018: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29663253/older-age-confers-a-higher-risk-of-30-day-morbidity-and-mortality-following-laparoscopic-bariatric-surgery-an-analysis-of-the-metabolic-and-bariatric-surgery-quality-improvement-program
#7
Ivy N Haskins, Tammy Ju, Ashlyn E Whitlock, Lisbi Rivas, Richard L Amdur, Paul P Lin, Khashayar Vaziri
INTRODUCTION: There is a paucity of literature describing the association of age with the risk of adverse events following bariatric surgery. The purpose of this study is to investigate the association of age with 30-day morbidity and mortality following laparoscopic bariatric surgery using the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database. METHODS: All adult patients undergoing laparoscopic Roux-en-Y gastric bypass (RNGYB) or sleeve gastrectomy (SG) were identified within the MBSAQIP database...
April 17, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29629485/has-the-time-come-to-be-more-aggressive-with-bariatric-surgery-in-obese-patients-with-chronic-systolic-heart-failure
#8
REVIEW
Amanda R Vest
PURPOSE OF REVIEW: Obesity is a strong risk factor for the development of heart failure (HF). Diet, exercise, and weight-loss pharmacotherapies have limited potential to achieve significant and sustainable weight loss, especially in patients with symptomatic systolic HF. This review seeks to determine the role of bariatric surgery for patients with systolic HF and obesity. RECENT FINDINGS: Bariatric surgeries such as the laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB) represent the most successful long-term strategy for achieving weight loss and diabetes and hypertension remission in the general obese population...
April 8, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29619914/iron-deficiency-after-bariatric-surgery-what-is-the-real-problem
#9
Nele Steenackers, Bart Van der Schueren, Ann Mertens, Matthias Lannoo, Tara Grauwet, Patrick Augustijns, Christophe Matthys
The growing prevalence of obesity explains the rising interest in bariatric surgery. Compared with non-surgical treatment options, bariatric surgery results in greater and sustained improvements in weight loss, obesity associated complications, all-cause mortality and quality of life. These encouraging metabolic and weight effects come with a downside, namely the risk of nutritional deficiencies. Particularly striking is the risk to develop iron deficiency. Postoperatively, the prevalence of iron deficiency varies between 18 and 53 % after Roux-en-Y gastric bypass and between 1 and 54 % after sleeve gastrectomy...
April 5, 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29618410/-long-term-outcomes-after-bariatric-and-metabolic-surgery
#10
Laurent Genser, Christophe Barrat
At long (≥5 years) and very long term (≥10 years) bariatric and metabolic surgery (BMS) is the only treatment that allows a significant and durable weight loss concomitant with a control of the different obesity related diseases. Regardless of the surgical technique, BMS significantly decrease long-term mortality (-30% at 15 years). The maximum weight loss is reached at postoperative year 2. Beyond, a weight regain and is usually observed in all procedures. The variability of long-term outcomes underlines the importance of multidisciplinary care throughout follow-up...
April 1, 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29616466/weight-loss-and-comorbidity-resolution-3-years-after-bariatric-surgery-an-indian-perspective
#11
Amrit Manik Nasta, Ramen Goel, Shefali Dharia, Madhu Goel, Shireen Hamrapurkar
INTRODUCTION: Bariatric surgery has seen a sharp rise in India in the last decade. India is one of the 10 most obese nations of the world, ranking second in number of type 2 diabetics. AIMS: To evaluate clinical outcomes of bariatric surgery after 3 years of follow-up in terms of weight loss, co-morbidity resolution, complaints of gastroesophageal reflux disease and weight regain. METHODOLOGY: All patients who underwent bariatric surgery from January to December 2013 with a minimum follow-up of 3 years were included in the study...
April 3, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29569341/bariatric-surgery-in-solid-organ-transplant-patients-long-term-follow-up-results-of-outcome-safety-and-effect-on-immunosuppression
#12
Renana Yemini, Eviatar Nesher, Janos Winkler, Idan Carmeli, Carmil Azran, Matan Ben David, Eytan Mor, Andrei Keidar
The surgical risk of transplanted patients is high, and the modified gastrointestinal anatomy after BS may lead to pharmacokinetic alterations in the absorption of immunosuppressive drugs. Data on outcomes of bariatric surgery (BS) and the safety and feasibility of maintaining immunosuppression and graft safety among solid-organ transplanted patients are scarce. In the current study, weight loss, improvement in comorbidities and changes in dosage and trough levels of immunosuppression drugs before and after BS were analyzed for all transplanted patients who underwent laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB) in our institution between 11/2011-1/2017...
March 22, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29549212/protocol-for-a-1-year-prospective-longitudinal-cohort-study-of-patients-undergoing-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-the-bari-lifestyle-observational-study
#13
Friedrich C Jassil, Alisia Carnemolla, Helen Kingett, Bruce Paton, Aidan G O'Keeffe, Jacqueline Doyle, Stephen Morris, Neville Lewis, Amy Kirk, Andrea Pucci, Kusuma Chaiyasoot, Rachel L Batterham
INTRODUCTION: Roux-en-Y gastric bypass and sleeve gastrectomy are the two most common bariatric surgery performed in the UK that result in comparable weight loss and remission of obesity-associated comorbidities. However, there is a paucity of studies examining the impact of these procedures on body composition, physical activity levels, sedentary behaviour, physical function and strength, dietary intake, health-related quality of life and costs. METHODS AND ANALYSIS: The BARI-LIFESTYLE observational study is a 1-year prospective, longitudinal cohort study within a real-world routine clinical care setting aiming to recruit 100 patients with severe obesity undergoing either primary Roux-en-Y gastric bypass or sleeve gastrectomy from two bariatric centres in London, UK...
March 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29530596/patients-preferences-for-information-in-bariatric-surgery
#14
Usha K Coblijn, Sjoerd M Lagarde, Christel A L de Raaff, Bart A van Wagensveld, Ellen M A Smets
BACKGROUND: The decision to undergo bariatric surgery is multifactorial and made both by patient and doctor. Information is of the utmost importance for this decision. OBJECTIVE: To investigate the bariatric surgery patient's preferences regarding information provision in bariatric surgery. SETTING: A teaching hospital, bariatric center of excellence in Amsterdam, the Netherlands. METHODS: All patients who underwent a primary laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy between September 2013 and September 2014 were approached by mail to participate...
May 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29525938/a-screening-study-of-potential-carcinogen-biomarkers-after-surgical-treatment-of-obesity
#15
Luciana Teixeira de Siqueira, Marcela Silvestre Outtes Wanderley, Roberto Afonso da Silva, Adriana da Silva Andrade Pereira, José Luiz de Lima Filho, Álvaro Antônio Bandeira Ferraz
BACKGROUND: Obesity has been associated with the development of various types of cancer. Biomarker studies may provide molecular level knowledge of the factors involved in this association, improving clinical practice through new methods of prevention and treatment. PURPOSE: The present study aimed to analyze proteins found in the plasma of obese patients prior to and 6 months after bariatric surgery, using body mass index (BMI) and percentage total weight loss (%TWL) to evaluate, in a prospective manner, the effects of weight loss on the regulation of proteins related to the appearance of tumors...
March 10, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29525261/postoperative-outcomes-in-bariatric-surgical-patients-participating-in-an-insurance-mandated-preoperative-weight-management-program
#16
Andrew Schneider, Deborah A Hutcheon, Allyson Hale, Joseph A Ewing, Megan Miller, John D Scott
BACKGROUND: Many insurance companies require patient participation in a medically supervised weight management program (WMP) before offering approval for bariatric surgery. Clinical data surrounding benefits of participation are limited. OBJECTIVE: To evaluate the relationship between preoperative insurance-mandated WMP participation and postoperative outcomes in bariatric surgery patients. SETTING: Regional referral center and teaching hospital...
May 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29516396/variation-in-exhaled-acetone-and-other-ketones-in-patients-undergoing-bariatric-surgery-a-prospective-cross-sectional-study
#17
Piers R Boshier, Matyas Fehervari, Sheraz R Markar, Sanjay Purkayastha, Patrik Spanel, David Smith, George B Hanna
BACKGROUND: Dietary restriction together with alteration of the gastrointestinal tract results in major metabolic changes and significant weight loss in patients undergoing bariatric surgery. Current methods of measuring these changes are often inaccurate and lack a molecular basis. The objective of this study was to determine the role of exhaled ketones as non-invasive markers of nutritional status in patients undergoing surgical treatment of obesity. METHODS: Patients at different stages of treatment for obesity were recruited to this single-centre cross-sectional study...
March 7, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29474284/pelvic-organ-prolapse-and-urinary-incontinence-in-women-after-bariatric-surgery-5-year-follow-up
#18
Iwona Gabriel, Ali Tavakkoli, Vatche A Minassian
OBJECTIVE: The objective of this study was to determine if weight loss surgery is associated with decreased prevalence of urinary incontinence (UI) and pelvic organ prolapse (POP) symptoms. METHODS: A survey was conducted among previously morbidly obese women who underwent bariatric surgery at Brigham and Women's Hospital, Boston from 2007 to 2015. In addition to the Pelvic Floor Distress Inventory 20, we collected demographic and clinical data including symptoms of and treatment for UI and POP before surgery...
March 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29460379/five-year-long-term-clinical-outcome-after-bariatric-metabolic-surgery-a-multi-ethnic-asian-population-in-singapore
#19
Bin C Toh, Weng H Chan, Alvin K H Eng, Eugene K W Lim, Chin H Lim, Kwang W Tham, Stephanie Fook-Chong, Jeremy T H Tan
Bariatric surgery is an effective treatment for morbid obesity and its metabolic related comorbidities; type 2 diabetes, hypertension and hyperlipidaemia.1 However, the literature is scarce regarding the long-term outcome after bariatric surgery, especially among multi-ethnic Asian populations. Considering the growing number of bariatric metabolic surgeries in Asia, we have attempted to provide a regional perspective on 5-year long-term clinical outcomes post bariatric surgery in Singapore. Between 2010 and 2016, all bariatric operative cases were included, and these comprised: laparoscopic sleeve gastrectomy (LSG), 393; laparoscopic Roux-En-Y gastric bypass (RYGB), 125; laparoscopic mini-gastric bypass (MGB), 43...
February 20, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29454535/insurance-mandated-preoperative-diet-and-outcomes-after-bariatric-surgery
#20
Charles J Keith, Lauren E Goss, Camille D Blackledge, Richard D Stahl, Jayleen Grams
BACKGROUND: Despite a lack of demonstrated patient benefit, many insurance providers mandate a physician-supervised diet before financial coverage for bariatric surgery. OBJECTIVES: To compare weight loss between patients with versus without insurance mandating a preoperative diet. SETTING: University hospital, United States. METHODS: Retrospective study of all patients who underwent laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy over a 5-year period, stratified based on whether an insurance-mandated physician-supervised diet was required...
February 2, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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