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veterinary medicine, dermatology

Stefano Caccavale, Diana Di Mattia, Eleonora Ruocco
Lately, the innovative concept of an immunocompromised cutaneous district (ICD) has been introduced to explain why a previously injured cutaneous site may become in time a privileged location for the onset of opportunistic infections, tumors, and immune reactions. The injuring events capable of rendering a skin region a potential ICD are various, numerous, and most of the time identifiable by means of a careful clinical history. The reason that only a small minority of injured skin areas actually becomes ICDs, with subsequent opportunistic localization of a second and unrelated skin disorder, is presently unknown...
September 2016: Clinics in Dermatology
Tosso Leeb, Eliane J Müller, Petra Roosje, Monika Welle
BACKGROUND: Molecular genetics has made significant advances in the analysis of hereditary dermatoses during the last several years. OBJECTIVES: To provide an update on currently available genetic tests for skin diseases of dogs, cats and horses, and to aid the veterinary clinician in the appropriate selection and applications of genetic tests. METHODS: The scientific literature on the topic was critically reviewed. The list of known causative variants for genodermatoses and hair morphology traits was compiled by searching the Online Mendelian Inheritance in Animals (OMIA) database...
July 18, 2016: Veterinary Dermatology
Stephen D White, David Sanchez-Migallon Guzman, Joanne Paul-Murphy, Michelle G Hawkins
BACKGROUND: Guinea pigs (Cavia porcellus) are popular companion animals with reported skin diseases, but most reports are accessed from textbooks or review articles. HYPOTHESIS/OBJECTIVES: To document skin diseases and their prevalence in companion guinea pigs in northern California, USA, and to investigate predilections for the most common conditions over a 25 year period. ANIMALS: Two hundred and ninety three guinea pigs from the hospital population met inclusion criteria...
October 2016: Veterinary Dermatology
Natascia Bruni, Maria Teresa Capucchio, Elena Biasibetti, Enrica Pessione, Simona Cirrincione, Leonardo Giraudo, Antonio Corona, Franco Dosio
Antimicrobial peptides (AMPs) represent a vast array of molecules produced by virtually all living organisms as natural barriers against infection. Among AMP sources, an interesting class regards the food-derived bioactive agents. The whey protein lactoferrin (Lf) is an iron-binding glycoprotein that plays a significant role in the innate immune system, and is considered as an important host defense molecule. In search for novel antimicrobial agents, Lf offers a new source with potential pharmaceutical applications...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Tina Koch, Ralf S Mueller, Britta Dobenecker, Andrea Fischer
Epilepsy is one of the most common neurologic disorders in dogs and life-long treatment with antiepileptic drugs (AED) is frequently required. Adverse events of AED targeting the skin are only rarely reported in veterinary medicine and the true incidence and spectrum of cutaneous reactions in epileptic dogs remains unknown. In this study, we hypothesized that cutaneous reactions commonly occur in epileptic dogs and are related to AED treatment. A retrospective case review of 185 dogs treated for epilepsy identified 20...
2016: Frontiers in Veterinary Science
Gagandeep Kaur, Victoria L Voith, Peggy L Schmidt
OBJECTIVE: To describe the prescribing habits of a sample of small animal veterinarians pertaining to use of fluoxetine in dogs and cats. DESIGN: Exploratory descriptive survey using a questionnaire, available on paper and through email, distributed to small animal veterinarians by convenience sampling. PARTICIPANTS: Veterinarians practicing small animal medicine in North America contacted by email and at local veterinary meetings. RESULTS: Of 127 initial respondents, 106 prescribed fluoxetine for dogs and/or cats...
2016: Veterinary Record Open
Sunita Dashrath Bansod, Manisha Subrashrao Bawaskar, Aniket Krishnarao Gade, Mahendra Kumar Rai
Many scientists have focused their research on the role of nanotechnology for the control of human pathogens, but there are also many topical pathogens present in animals, which infect animals and transfer to humans. Topical therapy is extremely important for the management of dermatological condition in animals. Therefore, the present study aims to evaluate the efficacy of biogenic silver nanoparticles (AgNPs) in combination with herbal oils against animal skin infections which may be responsible for causing infections in human beings...
August 2015: IET Nanobiotechnology
Karen K Ho, Karen L Campbell, Sidonie N Lavergne
BACKGROUND: Contact dermatitis (CD) is an inflammatory skin condition induced by direct contact with a specific chemical. Irritant CD (ICD) is a nonspecific inflammatory cutaneous reaction to an irritating agent. Allergic CD (ACD) is an immune-mediated antigen-specific skin reaction to an allergenic chemical. OBJECTIVES AND METHODS: The biomedical literature (human, basic science, veterinary) was reviewed to evaluate the current state of knowledge regarding CD. RESULTS: The incidence of human CD remains unclear, but represents up to 90-95% of all occupational skin diseases...
October 2015: Veterinary Dermatology
Khalid Ahmad, Mushtaq Ahmad, Caroline Weckerle
ETHNOPHARMACOLOGICAL RELEVANCE: Pastoralist tribal communities inhabit Thakht-e-Sulaiman hills since centuries. In this remote and geographically isolated area, local people mainly rely on their natural environment for ethnoveterinary care. The area is therefore of special interest for the documentation and analysis of ethnoveterinary plant use and efficacy. MATERIALS AND METHODS: Field work was conducted from 2010-2012 and 86 informants were interviewed. First, detailed unstructured interviews and group discussions were done with key informants, and second, successive oral freelisting and semi-structured interviews were performed...
July 21, 2015: Journal of Ethnopharmacology
Roberto Ciarcia, Sara Damiano, Alessia Florio, Manuela Spagnuolo, Enza Zacchia, Caterina Squillacioti, Nicola Mirabella, Salvatore Florio, Ugo Pagnini, Tiziana Garofano, Maria Sole Polito, Giovambattista Capasso, Antonio Giordano
Cyclosporine A (CsA) is the prototype of immunosuppressant drugs that has provided new perspectives in human and veterinary medicine to prevent organ transplant rejection and to treat certain autoimmune diseases and dermatologic diseases. Unfortunately, the treatment with CSA is often limited by severe adverse effects such as hypertension and nephrotoxicity. Some data suggest that reactive oxygen species (ROS) and the oxidative stress play an important role in its pathogenesis, in particular the superoxide (O2 (-)) that is the most powerful free radical generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase present mainly in the kidney...
September 2015: Journal of Cellular Biochemistry
R Seebaluck, A Gurib-Fakim, F Mahomoodally
ETHNOPHARMACOLOGICAL RELEVANCE: Acalypha is the fourth largest genus of the Euphorbiaceae family with approximately 450-570 species. Several Acalypha species are used as medicinal plants in Africa and in the Mascarene Islands. Almost every part of the plant including the leaves, stem and roots are used as traditional remedies to treat and manage a panoply of ailments. However, there is no updated compilation of traditionally important medicinal plants from the Acalypha genus. The present review therefore, endeavors to provide for the first time an updated compilation of documented ethnopharmacological information in relation to the ethnomedicinal, ethnoveterinary, zoopharmacognosy, phytochemistry and biological activities of medicinal plants from the Acalypha genus which can subsequently open new perspectives for further pharmacological research...
January 15, 2015: Journal of Ethnopharmacology
Simona Gabrielli, Alessio Giannelli, Emanuele Brianti, Filipe Dantas-Torres, Massimiliano Bufalini, Maurizio Fraulo, Francesco La Torre, Rafael A N Ramos, Cinzia Cantacessi, Maria Stefania Latrofa, Gabriella Cancrini, Domenico Otranto
Despite the widespread distribution of Cercopithifilaria bainae among canine and tick populations worldwide, this filarioid is currently considered of 'minor importance' in veterinary medicine, particularly when compared to related filarioids, such as Dirofilaria immitis and Dirofilaria repens. To date, only a single case of dermatological alterations possibly associated to infection by C. bainae had been reported in a dog. In the present study, we describe the first case of systemic alterations associated to C...
September 15, 2014: Veterinary Parasitology
Peter Forsythe, Sue Paterson
Ciclosporin is a lipophilic cyclic polypeptide with powerful immunosuppressive and immunomodulatory properties that has been used in veterinary medicine for two decades. It is a calcineurin inhibitor whose principal mode of action is to inhibit T cell activation. The drug is principally absorbed from the small intestine and is metabolised in the intestine and liver by the cytochrome P450 enzyme system. Ciclosporin is known to interact with a wide range of pharmacological agents. Numerous studies have demonstrated good efficacy for the management of canine atopic dermatitis and this has been a licensed indication since 2003...
March 2014: Veterinary Record
Paula A Schaffer, Bruce Wobeser, Michelle M Dennis, Colleen G Duncan
A retrospective study evaluated the clinical data and histologic features of non-neoplastic dermatologic lesions in skin biopsies from horses, donkeys, and mules submitted over a 10-year period to the Colorado State University Diagnostic Medicine Center and to the University of Saskatchewan Western College of Veterinary Medicine and Prairie Diagnostic Services. A total of 1793 non-neoplastic biopsies were available for analysis. Based on the histologic description and morphologic diagnosis, each submission was classified as inflammatory, or non-neoplastic/non-inflammatory...
March 2013: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
Aimee R Greenberg, Candace W Barnett
Prescribers practicing in metropolitan Atlanta were surveyed to examine their attitudes about compounding pharmacy, their perceived uses and indicated needs for compounding services, and their interest in learning more about compounding pharmacy. A questionnaire was mailed to random samples of 100 prescribers in each of the following specialties: veterinary, internal medicine, obstetrics and gynecology, and dermatology, with 25% responding. Attitudes toward compounding pharmacy were measured using 21 items and a five-point response scale (1 = strongly disagree)...
January 2004: International Journal of Pharmaceutical Compounding
(no author information available yet)
No abstract text is available yet for this article.
February 2013: Veterinary Dermatology
Wayne S Rosenkrantz, Craig E Griffin
No abstract text is available yet for this article.
November 2009: Compendium: Continuing Education for Veterinarians
Robert J Harman
Adult stem cells come from many sources and have the capacity to differentiate into many cell types, including those of the skin. The most commonly studied stem cells are those termed mesenchymal stem cells (MSCs), which are easily isolated from bone marrow and adipose tissue. Mesenchymal stem cells are known to produce a wide array of cytokines that modulate the regeneration process. The ease of collection, propagation and use of these MSCs in therapy of traumatic, ischaemic and immune-mediated skin conditions is emerging...
February 2013: Veterinary Dermatology
Mandy Burrows, Rusty Muse, Didier N Carlotti
No abstract text is available yet for this article.
February 2013: Veterinary Dermatology
Claudio Leto, Teresa Tuttolomondo, Salvatore La Bella, Mario Licata
ETHNOPHARMACOLOGICAL RELEVANCE: This paper illustrates the results of an ethnobotanical study carried out in the Madonie Regional Park (Central Sicily, Italy). It specifies the medicinal uses of plants in the study area and contains the results of a quantitative analysis carried out for the first time in an area noted for its high degree of biodiversity. It also introduces 28 species not previously accounted for in the area of study for their medicinal uses, highlighting Silene flos-cuculi L...
March 7, 2013: Journal of Ethnopharmacology
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