keyword
MENU ▼
Read by QxMD icon Read
search

Radiation bowel

keyword
https://www.readbyqxmd.com/read/29139310/pudendal-nerve-injury-impairs-anorectal-function-and-health-related-quality-of-life-measures-%C3%A2-2-years-after-3d-conformal-radiotherapy-for-prostate-cancer
#1
Eng Eric Yeoh, Rochelle Botten, Addolorata Di Matteo, Marcus Tippett, Jonathon Hutton, Robert Fraser, Phillip G Dinning, David Wattchow
PURPOSE: To compare GI symptoms, measures of generic and disease specific health related quality of life (HRQoL), anorectal and pudendal nerve function and anal sphincter morphology between (i) patients ≥2 years after 3D conformal radiotherapy (3D-CRT)±high dose rate (HDR) brachytherapy for carcinoma of the prostate and aged matched patients before radiotherapy and (ii) symptomatic and asymptomatic patients ≥2 years after 3D-CRT ± HDR brachytherapy. MATERIAL AND METHODS: Methodology included: (i) modified LENT-SOMA scales for GI symptoms, (ii) EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires for generic and disease specific HRQoL, (iii) anorectal manometry and terminal motor latency for anorectal and pudendal nerve function and (iv) endorectal ultrasound for anal sphincter morphology...
November 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29139208/a-knowledge-based-approach-to-automated-planning-for-hepatocellular-carcinoma
#2
Yujie Zhang, Tingting Li, Han Xiao, Weixing Ji, Ming Guo, Zhaochong Zeng, Jianying Zhang
PURPOSE: To build a knowledge-based model of liver cancer for Auto-Planning, a function in Pinnacle, which is used as an automated inverse intensity modulated radiation therapy (IMRT) planning system. METHODS AND MATERIALS: Fifty Tomotherapy patients were enrolled to extract the dose-volume histograms (DVHs) information and construct the protocol for Auto-Planning model. Twenty more patients were chosen additionally to test the model. Manual planning and automatic planning were performed blindly for all twenty test patients with the same machine and treatment planning system...
November 15, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29131764/nongynecologic-findings-seen-at-pelvic-us
#3
Akram M Shaaban, Maryam Rezvani, Jeffrey D Olpin, Anne M Kennedy, Ayman H Gaballah, Bryan R Foster, Christine O Menias, Khaled M Elsayes
Ultrasonography (US) is frequently the first imaging modality used to examine women with symptoms involving the pelvis. It is widely available and involves no exposure to ionizing radiation. Images can be acquired with a transabdominal, endovaginal, or translabial approach, and the use of video clips and three-dimensional reconstructions can be helpful. US is excellent for assessment of the uterus, ovaries, and adnexa. Occasionally, nongynecologic pelvic diseases arising from the gastrointestinal, genitourinary, and musculoskeletal systems and the pelvic peritoneal and extraperitoneal spaces may be detected and can be a source of diagnostic dilemma...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29130230/-protective-measures-in-laparoscopic-resection-for-upper-or-mid-rectal-cancer-and-sigmoid-colon-cancer-with-transrectal-specimen-extraction-surgery
#4
Chuangang Fu, Zhuqing Zhou, Junyi Han, Bin Lu, Wei Gao, Zhe Zhu, Qixin Jiang, Fang Ji, Tao Du
OBJECTIVE: To introduce the use of a self-made specimen protective sleeve in laparoscopic resection for upper or mid rectal cancer and sigmoid colon cancer with transrectal specimen extraction surgery and the improvement of implantation method, so as to avoid and reduce bacterial contamination and tumor cell dissemination in abdominal cavity. METHODS: During June 2015 and May 2017, 48 cases of high located rectal or sigmoid colon cancer were operated laparoscopically with natural orifices specimen extraction surgery (NOSES) using a self-made specimen protecting sleeve...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29129469/does-the-use-of-volumetric-modulated-arc-therapy-reduce-gastrointestinal-symptoms-after-pelvic-radiotherapy
#5
K L White, E Varrassi, J A Routledge, L H Barraclough, J E Livsey, J McLaughlin, S E Davidson
AIMS: Growing numbers of patients with cancer are surviving after treatment with pelvic radiotherapy. We evaluated the technique of volumetric modulated arc therapy (VMAT), which delivers a decreased dose to the organs at risk. We aimed to determine outcomes of this technique in terms of patient-reported acute toxicity and late effects and correlate the frequency of gastrointestinal symptoms with the volume of bowel receiving radiation dose. MATERIALS AND METHODS: Patients who were to receive VMAT for gynaecological malignancy completed patient-reported outcomes at baseline, the end of treatment, 8 weeks and 1 year...
November 9, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29114614/preoperative-radiation-dose-escalation-for-rectal-cancer-using-a-concomitant-boost-strategy-improves-tumor-downstaging-without-increasing-toxicity-a-matched-pair-analysis
#6
Jillian R Gunther, Awalpreet S Chadha, Ui Sup Shin, In Ja Park, Kiran V Kattepogu, Jonathan D Grant, David C Weksberg, Cathy Eng, Scott E Kopetz, Prajnan Das, Marc E Delclos, Harmeet Kaur, Dipen M Maru, John M Skibber, Miguel A Rodriguez-Bigas, Y Nancy You, Sunil Krishnan, George J Chang
Purpose: Pathologic complete response to neoadjuvant chemoradiation therapy (CRT) is associated with improved outcomes for patients with locally advanced rectal cancer (LARC). Increased response rates have been reported with higher radiation doses, but these studies often lack long-term outcome and/or toxicity data. We conducted a case-control analysis of patients with LARC who underwent definitive CRT to determine the efficacy and safety of intensified treatment with a concomitant boost (CB) approach...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114613/acr-appropriateness-criteria-for-external-beam-radiation-therapy-treatment-planning-for-clinically-localized-prostate-cancer-part-ii-of-ii
#7
REVIEW
Nicholas G Zaorsky, Timothy N Showalter, Gary A Ezzell, Paul L Nguyen, Dean G Assimos, Anthony V D'Amico, Alexander R Gottschalk, Gary S Gustafson, Sameer R Keole, Stanley L Liauw, Shane Lloyd, Patrick W McLaughlin, Benjamin Movsas, Bradley R Prestidge, Al V Taira, Neha Vapiwala, Brian J Davis
Purpose: To present the most updated American College of Radiology (ACR) Appropriateness Criteria formed by an expert panel on the appropriate delivery of external beam radiation to manage stage T1 and T2 prostate cancer (in the definitive setting and post-prostatectomy) and to provide clinical variants with expert recommendations based on accompanying Appropriateness Criteria for target volumes and treatment planning. Methods and materials: The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a panel of multidisciplinary experts...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114589/long-term-economic-value-of-hypofractionated-prostate-radiation-secondary-analysis-of-a-randomized-trial
#8
K Ranh Voong, Lincy S Lal, Deborah A Kuban, Thomas J Pugh, J Michael Swint, Joy Godby, Seungtaek Choi, Andrew K Lee, Pamela J Schlembach, Steven J Frank, Sean E McGuire, Karen E Hoffman
Purpose: Moderately hypofractionated intensity modulated radiation therapy (HIMRT) for prostate cancer shortens the treatment course while providing outcomes comparable with those of conventional intensity modulated radiation therapy (CIMRT). To determine the long-term economic value of HIMRT, including the costs of managing long-term radiation toxicities, a cost minimization analysis compared CIMRT with dose-escalated HIMRT using patient-level data from a randomized trial. Methods and materials: Men with localized prostate cancer were randomized to CIMRT (75...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29113519/does-the-low-fodmap-diet-improve-symptoms-of-radiation-induced-enteropathy-a-pilot-study
#9
Trine Larsen, Trygve Hausken, Synne Otteraaen Ystad, Nils Hovdenak, Bernd Mueller, Gülen Arslan Lied
RATIONALE: Patients with radiation-induced enteropathy (RE) after cancer treatment show similar symptoms as patients with irritable bowel syndrome (IBS). The low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet (LFD) is a widespread management strategy for IBS. We aimed to investigate if there may be a positive effect of LFD on symptoms and health-related quality of life (HRQOL) in patients with RE. METHODS: In an open non-controlled pilot study, 11 patients (all female) with RE-related IBS symptoms were recruited largely based on own initiative...
November 7, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29106365/validation-of-the-french-canadian-version-of-the-expanded-prostate-cancer-index-composite-epic-in-a-french-canadian-population
#10
Éric Vigneault, Josée Savard, Marie-Hélène Savard, Hans Ivers, Philippe Després, William Foster, André-Guy Martin, Vincent Fradet
INTRODUCTION: This study aims to empirically validate the French-Canadian version of the Expanded Prostate Cancer Index Composite (EPIC), a measure of health-related quality of life for prostate cancer patients. METHODS: 251 participants completed a battery of self-report scales including the French-Canadian version of the EPIC, after having received radiation therapy or radical prostatectomy for prostate cancer. RESULTS: The internal consistency for the urinary incontinence, bowel, and sexual domains of the EPIC-26 was high (Cronbach's alpha coefficients from ...
November 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29101643/dosimetric-comparison-of-3-dimensional-conformal-radiotherapy-volumetric-modulated-arc-therapy-and-helical-tomotherapy-for-postoperative-gastric-cancer-patients
#11
Cem Onal, Yemliha Dölek, Berna Akkuş Yıldırım
PURPOSE: To compare dosimetric data for the planning target volume (PTV) and organs at risk (OARs) between 3-dimensional conformal radiotherapy (3DCRT), volumetric modulated arc therapy (VMAT), and helical tomotherapy [1]. MATERIALS AND METHODS: The dosimetric data for 15 gastric cancer patients treated with 3DCRT, VMAT, or HT techniques were used. Cumulative dosimetric parameters, homogeneity index (HI), and conformal index (CI) were compared for the PTV and OARs...
November 3, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29081651/comparison-of-patients-tolerance-between-computed-tomography-enterography-and-double-balloon-enteroscopy
#12
Maochen Zhang, Tianyu Zhang, Liwen Hong, Qiangqiang Wu, Yun Lin, Mengfan Xie, Rong Fan, Zhengting Wang, Jie Zhou, Jie Zhong
BACKGROUND: Computed tomography enterography (CTE) and double-balloon enteroscopy (DBE) are widely used in diagnosis of small bowel diseases. Both of these examinations bring discomfort to patients. The aim of this study was to compare patients' tolerance and preference between CTE and DBE. METHODS: From August 1, 2014 to December 31, 2016, patients with suspected or known small bowel diseases who underwent both CTE and DBE were prospectively enrolled in our study...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29052734/diagnostic-performance-of-magnetic-resonance-enterography-for-detection-of-active-inflammation-in-children-and-adolescents-with-inflammatory-bowel-disease-a-systematic-review-and-diagnostic-meta-analysis
#13
Hee Mang Yoon, Chong Hyun Suh, Jeong Rye Kim, Jin Seong Lee, Ah Young Jung, Kyung Mo Kim, Young Ah Cho
Importance: Magnetic resonance (MR) enterography has the advantage over other techniques of being noninvasive, lacking ionizing radiation, and demonstrating excellent soft-tissue contrast to evaluate pediatric patients with inflammatory bowel disease (IBD). Objective: To evaluate the diagnostic performance of MR enterography for detection of active inflammation in children and adolescents with known or suspected IBD. Data Sources: A search of MEDLINE and EMBASE up to January 2, 2017, was performed to identify studies...
October 9, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/29050211/silibinin-attenuates-radiation-induced-intestinal-fibrosis-and-reverses-epithelial-to-mesenchymal-transition
#14
Joong Sun Kim, Na-Kyung Han, Sung-Ho Kim, Hae-June Lee
Radiotherapy is a common treatment for cancer patients, but its use is often restricted by the tolerance of normal tissue. As cancer patients live longer, delayed radiation effects on normal tissue have become a concern. Radiation-induced enteropathy, including inflammatory bowel disease and fibrosis, are major issues for long-term cancer survivors. To investigate whether silibinin attenuates delayed radiation-induced intestinal injury in mice, we focused on intestinal fibrotic changes. Silibinin improved delayed radiation injuries in mice in association with decreased collagen deposition within the intestines and deceased transforming growth factor (TGF)-β1 levels in the intestine and plasma...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29034790/minimal-toxicity-after-proton-beam-therapy-for-prostate-and-pelvic-nodal-irradiation-results-from-the-proton-collaborative-group-reg001-09-trial
#15
Michael D Chuong, William Hartsell, Gary Larson, Henry Tsai, George E Laramore, Carl J Rossi, J Ben Wilkinson, Adeel Kaiser, Carlos Vargas
BACKGROUND: Proton beam therapy (PBT) reduces normal organ dose compared to intensity modulated radiation therapy (IMXT) for prostate cancer patients who receive pelvic radiation therapy. It is not known whether this dosimetric advantage results in less gastrointestinal (GI) and genitourinary (GU) toxicity than would be expected from IMXT. MATERIAL AND METHODS: We evaluated treatment parameters and toxicity outcomes for non-metastatic prostate cancer patients who received pelvic radiation therapy and enrolled on the PCG REG001-09 trial...
October 14, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29034307/uterine-clostridium-perfringens-infection-related-to-gynecologic-malignancy
#16
Kevin M Kremer, Megan E McDonald, Michael J Goodheart
Uterine gas gangrene caused by Clostridium perfringens is a serious, often life-threatening infection that is rarely encountered in the practice of gynecologic oncology. However, the hypoxic nature of gynecologic cancers due to necrosis and/or prior radiation therapy creates a microenvironment optimal for proliferation of anaerobic bacteria such as the Clostridium species. Early recognition and aggressive treatment with IV antibiotics and surgical debridement remain the cornerstones of management in order to decrease morbidity and mortality...
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29028221/quality-of-life-and-patient-reported-outcomes-following-proton-radiation-therapy-a-systematic-review
#17
REVIEW
Vivek Verma, Charles B Simone, Mark V Mishra
Background: As costs of cancer care rise, the importance of documenting value in oncology increases. Proton beam radiotherapy (PBT) has the potential to reduce toxicities in cancer patients, but is relatively expensive and unproven. Evaluating quality of life (QOL) and patient-reported outcomes (PROs) is essential to establishing PBT's "value" in oncologic therapy. The goal of this systematic review was to assess QOL and PROs in patients treated with PBT. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-guided systematic searches were conducted...
April 1, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29023527/dose-escalated-radiotherapy-for-unresectable-or-locally-recurrent-pancreatic-cancer-dose-volume-analysis-toxicity-and-outcome-of-28-consecutive-patients
#18
Sebastian Zschaeck, Bibiana Blümke, Peter Wust, David Kaul, Marcus Bahra, Hanno Riess, Fritz Klein, Marianne Sinn, Uwe Pelzer, Volker Budach, Pirus Ghadjar
PURPOSE: The role of radiotherapy for unresectable pancreatic cancer is controversial. A benefit of additional radiotherapy is supported by some observations. A dose-effect relationship was recently found by dose escalation employing image guided and intensity modulated radiotherapy. METHODS: We retrospectively evaluated 28 consecutive patients, all with history of extensive prior therapies for unresectable locally advanced/ recurrent pancreatic cancer (LAPC/LRPC)...
2017: PloS One
https://www.readbyqxmd.com/read/28994459/neural-network-dose-models-for-knowledge-based-planning-in-pancreatic-sbrt
#19
Warren G Campbell, Moyed Miften, Lindsey Olsen, Priscilla Stumpf, Tracey Schefter, Karyn A Goodman, Bernard L Jones
PURPOSE: Stereotactic body radiation therapy (SBRT) for pancreatic cancer requires a skillful approach to deliver ablative doses to the tumor while limiting dose to the highly sensitive duodenum, stomach, and small bowel. Here, we develop knowledge-based artificial neural network dose models (ANN-DMs) to predict dose distributions that would be approved by experienced physicians. METHODS: Arc-based SBRT treatment plans for 43 pancreatic cancer patients were planned, delivering 30-33 Gy in five fractions...
October 10, 2017: Medical Physics
https://www.readbyqxmd.com/read/28986677/split-bolus-single-scan-cta-for-evaluation-of-mesenteric-ischemia
#20
Patricia C Jo, Fernanda C Cabral, Azize Sahin, Andrés Camacho, Alexander Brook, Olga R Brook
PURPOSE: To evaluate split-bolus single scan CTA protocol for evaluation of acute mesenteric ischemia. MATERIALS AND METHODS: In this HIPAA-compliant IRB-approved study, consecutive patients evaluated for mesenteric ischemia between 11/2015 and 10/2016 were included. Patients scanned prior to 4/2016 were scanned with multiphasic CTA protocol and after with split-bolus single scan CTA. Objective and subjective evaluation was performed by three board-certified readers...
October 6, 2017: Abdominal Radiology
keyword
keyword
24231
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"