keyword
https://read.qxmd.com/read/38590778/a-review-of-long-non-coding-rnas-in-ankylosing-spondylitis-pathogenesis-clinical-assessment-and-therapeutic-targets
#21
REVIEW
Hanji Wang, Chengxian Yang, Ge Li, Boning Wang, Longtao Qi, Yu Wang
Ankylosing spondylitis (AS) is a chronic immune-mediated type of inflammatory arthritis characterized by inflammation, bone erosion, and stiffness of the spine and sacroiliac joints. Despite great efforts put into the investigation of the disease, the pathogenesis of AS remains unclear, posing challenges in identifying ideal targets for diagnosis and treatment. To enhance our understanding of AS, an increasing number of studies have been conducted. Some of these studies reveal that long non-coding RNAs (lncRNAs) play crucial roles in the etiology of AS...
2024: Frontiers in Cell and Developmental Biology
https://read.qxmd.com/read/38588592/successful-coil-embolization-of-a-ruptured-pseudoaneurysm-of-the-superior-gluteal-artery-after-a-percutaneous-awake-robot-assisted-sacroiliac-joint-fusion-illustrative-case
#22
JOURNAL ARTICLE
Samah Morsi, Alyssa M Bartlett, Andrew A Hardigan, Mounica Paturu, Shawn W Adams, Malcolm R DeBaun, Waleska Pabon-Ramos, Muhammad M Abd-El-Barr
BACKGROUND: Robot-assisted sacroiliac joint (SIJ) fusion has gained popularity, but it carries the risk of complications such as injury to the superior gluteal artery (SGA). The authors present the case of an awake percutaneous robot-assisted SIJ fusion leading to an SGA pseudoaneurysm. OBSERVATIONS: An 80-year-old male, who had undergone an awake percutaneous robot-assisted SIJ fusion, experienced postoperative left hip pain and bruising. Subsequent arteriography demonstrated an SGA branch pseudoaneurysm requiring coil embolization...
April 8, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38586083/-whatever-i-said-didn-t-register-with-her-medical-fatphobia-and-interactional-and-relational-disconnect-in-healthcare-encounters
#23
JOURNAL ARTICLE
Carolin Kost, Kimberly Jamie, Elizabeth Mohr
INTRODUCTION: This article focuses on medical fatphobia as a specific phenomenon structuring interactions between patients and healthcare practitioners. Throughout the article, we use 'fat' and 'fatphobia' as the preferred terms in the body positivity and fat acceptance communities. It is well documented that 'fat' people frequently experience negative and highly stigmatising healthcare encounters where weight is disproportionately centred and over-attributed as a cause of ill-health...
2024: Frontiers in sociology
https://read.qxmd.com/read/38584563/network-pharmacology-and-experimental-verification-of-si-shen-decoction-regulating-fabp4-ppar%C3%AE-nf%C3%AE%C2%BAb-pathway-in-the-treatment-of-collagen-induced-arthritis
#24
JOURNAL ARTICLE
Rui Guan, Jiashu Yao, Qing Qi, Jing Yu, Ruoshi Liu, Mingli Gao
AIM: This study aimed to investigate the mechanism of SSD in rats with Collagen- Induced Arthritis (CIA). BACKGROUND: Rheumatoid arthritis (RA) is a complex immune disease characterized by bilateral symmetrical multi-joint pain and swelling. Si Shen Decoction (SSD) has shown good results in treating RA in clinical applications, but its mechanism of action remains unclear. OBJECTIVE: To investigate the mechanism of SSD in rats with Collagen-Induced Arthritis (CIA)...
April 3, 2024: Combinatorial Chemistry & High Throughput Screening
https://read.qxmd.com/read/38582820/how-to-inject-sacroiliac-joints-with-ultrasound-guidance-a-pictorial-essay
#25
JOURNAL ARTICLE
Suhel G Al Khayyat, Paolo Falsetti, Annarita Saponara, Salvatore Massimo Stella, Alberto Migliore, Andrea Del Chiaro, Luca Cantarini, Bruno Frediani
Active sacroiliitis and sacroiliac joint dysfunction represent a common cause of low back pain in the population and are cause of patients' quality of life reduction and disability worldwide. The use of musculoskeletal ultrasound allows to easily identify the sacroiliac joints and to study every pathological condition affecting its most dorsal part; moreover, musculoskeletal ultrasound allows to guide highly effective injective procedures aimed at improving patients' symptoms and enhance their well-being. This paper aims to briefly explain for the musculoskeletal sonographer the anatomy and biomechanics of the sacroiliac joints, the correct ultrasound scanning method for their visualization and the most appropriate ultrasound guided injection technique to help dealing with the diagnostic and management of sacroiliac joint pain in the everyday scenario...
April 6, 2024: Journal of Ultrasound
https://read.qxmd.com/read/38580773/radiologic-evaluation-of-ankle-fracture-malunions-of-the-fibula
#26
REVIEW
Sam Si-Hyeong Park, Timothy L Miao, Ali Naraghi, Dorota Linda, Lawrence M White
Ankle fractures involving the distal fibula are common injuries. Malreductions and subsequent malunions of the distal fibula can result in worse clinical outcomes and posttraumatic arthritis. The ability to accurately evaluate and identify malreductions and malunions of the distal fibula is important. A number of different radiographic and CT measurements have been described to assess fibular length and rotation. This review highlights various radiologic measures and discusses their advantages and limitations...
April 6, 2024: Skeletal Radiology
https://read.qxmd.com/read/38580353/correction-validation-of-sparcc-mri-retic-e-tools-for-increasing-scoring-proficiency-of-mri-sacroiliac-joint-lesions-in-axial-spondyloarthritis
#27
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 5, 2024: RMD Open
https://read.qxmd.com/read/38580341/diagnostic-accuracy-in-axial-spondyloarthritis-a-systematic-evaluation-of-the-role-of-clinical-information-in-the-interpretation-of-sacroiliac-joint-imaging
#28
JOURNAL ARTICLE
Tim Pohlner, Dominik Deppe, Katharina Ziegeler, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Valeria Rios Rodriguez, Murat Torgutalp, Jürgen Braun, Torsten Diekhoff, Denis Poddubnyy
OBJECTIVES: Radiography and MRI of the sacroiliac joints (SIJ) are relevant for the diagnosis and classification of patients with axial spondyloarthritis (axSpA). This study aimed to evaluate the impact of clinical information (CI) on the accuracy of imaging interpretation. METHODS: Out of 109 patients referred because of suspicion of axSpA with complete imaging sets (radiographs and MRI of SIJ), 61 were diagnosed with axSpA (56%). Images were independently evaluated by three radiologists in four consecutive reading campaigns: radiographs and radiographs+MRI without and with CI including demographic data, SpA features, physical activity and pregnancy...
April 4, 2024: RMD Open
https://read.qxmd.com/read/38579775/multidirectional-instability-of-the-shoulder-a-systematic-review-with-a-novel-classification
#29
JOURNAL ARTICLE
Victor Housset, Sean Wei Loong Ho, Alexandre Lädermann, Sean Kean Ann Phua, Si Jian Hui, Geoffroy Nourissat
PURPOSE: A variety of instabilities are grouped under multidirectional instability (MDI) of the shoulder. This makes understanding its diagnostic process, presentation and treatment difficult due to lack of evidence-based consensus. This review aims to propose a novel classification for subtypes of MDI. METHODS: A systematic search was performed on PubMed Medline and Embase. A combination of the following 'MeSH' and 'non-MesH' search terms were used: (1) Glenohumeral joint[tiab] OR Glenohumeral[tiab] OR Shoulder[tiab] OR Shoulder joint[tiab] OR Shoulder[MeSH] OR Shoulder joint[MeSH], (2) Multidirectional[tiab], (3) Instability[tiab] OR Joint instability[MeSH]...
April 4, 2024: EFORT Open Reviews
https://read.qxmd.com/read/38579573/frequency-compensated-diffusion-model-for-real-scene-dehazing
#30
JOURNAL ARTICLE
Jing Wang, Songtao Wu, Zhiqiang Yuan, Qiang Tong, Kuanhong Xu
Due to distribution shift, deep learning based methods for image dehazing suffer from performance degradation when applied to real-world hazy images. In this paper, this study considers a dehazing framework based on conditional diffusion models for improved generalization to real haze. First, our work finds that optimizing the training objective of diffusion models, i.e., Gaussian noise vectors, is non-trivial. The spectral bias of deep networks hinders the higher frequency modes in Gaussian vectors from being learned and hence impairs the reconstruction of image details...
March 28, 2024: Neural Networks: the Official Journal of the International Neural Network Society
https://read.qxmd.com/read/38578007/coexistence-of-ankylosing-spondylitis-and-beh%C3%A3-et-s-disease-successful-treatment-with-upadacitinib
#31
JOURNAL ARTICLE
Krasimir Kraev, Petar Uchikov, Bozhidar Hristov, Maria Kraeva, Yordanka Basheva-Kraeva, Stanislava Popova-Belova, Milena Sandeva, Dzhevdet Chakarov, Snezhanka Dragusheva, Mariela Geneva-Popova
BACKGROUND: Ankylosing spondylitis (AS) and Behçet's disease (BD) are distinct inflammatory disorders, but their coexistence is a rare clinical entity. This case sheds light on managing this complex scenario with Janus kinase (JAK) inhibitors. CASE PRESENTATION: A 42-year-old woman presented with a decade-long history of lower back pain, nocturnal spinal discomfort, recurrent eye issues, oral and genital ulcers, hearing loss, pus formation in the left eye, and abdominal pain...
April 2024: Immunity, Inflammation and Disease
https://read.qxmd.com/read/38577549/risk-factors-and-characteristics-of-in-hospital-falls-after-spine-surgery-a-retrospective-single-center-cohort-study-in-the-republic-of-korea
#32
JOURNAL ARTICLE
Jae-Won Shin, Heon Jung Park, Yung Park, Joong-Won Ha, Jung Hwa Hong, Hak-Sun Kim, Kyung-Soo Suk, Seong-Hwan Moon, Si-Young Park, Byung-Ho Lee, Ji-Won Kwon
BACKGROUND: Falls after orthopaedic surgery can cause serious injuries, which lengthen hospital stays and increase medical expenses. This has prompted hospitals to implement various fall-prevention protocols. The aims of this study were to determine the incidence of in-hospital falls after spine surgery, to analyze the overall risk factors, to discern factors that have a major influence on falls, and to evaluate the effectiveness of the fall-prevention protocol that we implemented. METHODS: This was a retrospective, single-center study including patients who underwent spine surgery from January 2011 to November 2021 at the National Health Insurance Service Ilsan Hospital (NHISIH) in Goyang, Republic of Korea...
2024: JB & JS Open Access
https://read.qxmd.com/read/38576118/the-effects-of-using-heel-protectors-on-the-prevention-of-heel-pressure-injuries-and-plantar-flexion-contractures
#33
JOURNAL ARTICLE
Kubra Arslan, Sebahat Ates
BACKGROUND: Immobilization in the intensive care unit can lead to pressure injuries and plantar flexion contractures. AIM: This study was conducted to evaluate the effectiveness of heel protectors applied for the prevention of heel pressure injuries and plantar flexion contractures in intensive care units. METHODOLOGY: This study was conducted as a randomized controlled trial in two adult intensive care units of a teaching and research hospital...
April 4, 2024: Nursing in Critical Care
https://read.qxmd.com/read/38567561/sarcoidosis-as-a-cause-of-chronic-back-pain-a-case-report
#34
JOURNAL ARTICLE
Georges El Hasbani, Jessica Nicolas, Vicky Najjar, Ali Jawad, Imad Uthman
While sarcoidosis is typically a multisystem disease, it can, in some instances, exclusively affect the vertebrae, leading to back pain. Additionally, sarcoidosis may manifest with inflammation of the sacroiliac joints, not meeting the criteria for spondyloarthritis, yet contributing to back pain. In this report, we present a case involving a previously healthy 55-year-old woman who sought medical attention due to chronic back pain. She was subsequently diagnosed with spinal sarcoidosis, based on MRI, PET scan, and biopsy results...
March 26, 2024: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://read.qxmd.com/read/38567231/a-case-report-of-sj%C3%A3-gren-s-syndrome-and-rheumatoid-arthritis-the-role-of-physiotherapy-in-enhancing-quality-of-life
#35
Sawari S Bhagwatkar, Pallavi Harjpal, Prajyot Ankar
Rheumatoid arthritis (RA) is a systemic autoimmune disease with profound effects on joints and extra-articular organs. This case report explores the complex treatment approach for a 54-year-old female patient who is dealing with the dual diagnosis of RA and Sjogren's syndrome (SS). RA primarily involves joint inflammation and morning stiffness leading to significant disability, while SS, another autoimmune condition, manifests with autoantibodies and lymphocytic infiltration affecting exocrine glands. The patient presented with joint and low back pain, alongside reduced mobility, portraying a complex clinical picture...
March 2024: Curēus
https://read.qxmd.com/read/38567009/intraoperative-fat-embolism-syndrome-associated-with-implantation-of-titanium-sacroiliac-joint-fusion-implants-a-report-of-two-cases
#36
Alexander C Aretakis, James P Farrell, David C Ou-Yang, Christopher J Kleck
BACKGROUND: For patients undergoing long-construct fusion surgeries, simultaneous sacroiliac joint (SIJ) fusion is a growing trend in spine surgery. Some options for posterior SIJ fusion include 3D-printed triangular titanium implants or self-harvesting SIJ screws. Both implants require fixation within the sacrum and ileum. Fat embolism syndrome is a rare but known complication of lumbar pedicle instrumentation but has never been reported in association with SIJ fusion, regardless of implant type...
March 20, 2024: Journal of Spine Surgery (Hong Kong)
https://read.qxmd.com/read/38563276/glastonbury-festival-medical-care-at-the-world-s-largest-greenfield-music-festival
#37
JOURNAL ARTICLE
Jack F Bennett, David J Cottrell
INTRODUCTION: Music festivals have become an increasingly popular form of mass-gathering event, drawing an increasing number of attendees across the world each year. While festivals exist to provide guests with an enjoyable experience, there have been instances of serious illness, injury, and in some cases death. Large crowds, prolonged exposure to loud music, and high rates of drug and alcohol consumption can pose a dangerous environment for guests as well as those looking after them...
April 2, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38560587/accuracy-of-intraoperative-approximation-of-pelvic-tilt-using-preoperative-standing-radiographs
#38
JOURNAL ARTICLE
William Oetojo, Patrick Lawler, Hassan Farooq, Jim Pierrepont, Daniel Schmitt, Nicholas Brown
BACKGROUND: Anterior approach surgeons who utilize intraoperative fluoroscopy often try to match a preoperative radiograph as a reference for intraoperative cup position. Every degree of inaccuracy in tilt leads to a roughly 0.7° change in anteversion. This study aimed to determine how closely pelvic tilt (PT) is approximated intraoperatively when compared to preoperative anteroposterior (AP) radiographs. METHODS: This was a retrospective review of 193 primary THA's done by 2 surgeons at an academic tertiary referral center between September 2021-January 2023...
August 2024: Journal of Orthopaedics
https://read.qxmd.com/read/38560196/microstructural-characterization-and-corrosion-resistance-behavior-of-friction-stir-welded-a390-10%C3%A2-wt-sic-composites-aa2024-al-alloy-joints
#39
JOURNAL ARTICLE
Hamed Jamshidi Aval, Ivan Galvão
This study examined the effect of traverse speed on the mechanical properties, corrosion-resistance behavior, and microstructure of friction stir-welded A390/10 wt% SiC composites-AA2024 Al alloy joints. The laminar flow of both materials was found to diminish in the stir zone (SZ) when the traverse speed of the tool increased from 40 to 80 mm/min, lowering their mixing rate. Large aspect ratio Si particles are broken by the tool pin-induced applied plastic strain, which turns them into refined equiaxed particles...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38559797/piriformis-syndrome-as-an-overlooked-cause-of-pain-in-a-patient-with-axial-spondyloarthritis-a-case-report
#40
Ezgi Akyildiz Tezcan, Kemal Erol, Ilknur Albayrak Gezer
Piriformis syndrome is a neuromuscular disorder characterized by hip, buttock, and leg pain. Axial spondyloarthritis is a rheumatic disease primarily affecting the sacroiliac joint and the spine. Due to their anatomical proximity, the potential relationship between piriformis syndrome and sacroiliitis has been discussed for some time. However, literature review revealed that there is no study on piriformis syndrome in individuals with axial spondyloarthritis. Here, we present the case of a 30-year-old female with axial spondyloarthritis who developed severe low back, hip, and buttock pain that persisted despite initial treatment for axial spondyloarthritis...
April 1, 2024: Journal of rheumatic diseases
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