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Poly cystic ovarian syndrome

Nitika Gupta, Shilpa Bhandari, Pallavi Agrawal, Ishita Ganguly, Aparna Singh
Objective: This study aims to study the difference in etiology and outcome in terms of implantation rate and abortion rate in fresh (self-stimulated) versus frozen (oocyte donation cycle) in vitro fertilization (IVF) and in transient versus persistent fluid. Material and Methods: This retrospective study was conducted in the Department of Reproductive Medicine of tertiary care center from January 2012 to November 2015. Data were collected retrospectively from the departmental files...
October 2017: Journal of Human Reproductive Sciences
Chun-Man Lee
Poly cystic ovarian syndrome (PCOS) has been described as the common diagnosis for hirsutism in women. Facial hirsutism is by far the most distressing symptom of hyperandrogenism in women with PCOS. A statistically significant improvement in psychological well-being has been reported in patients with PCOS allocated for laser-assisted hair removal. The theory of selective photothermolysis has revolutionized laser hair removal in that it is effective and safe, when operated by sufficiently trained and experienced professionals...
June 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Larissa Paixão, Ramon B Ramos, Anita Lavarda, Debora M Morsh, Poli Mara Spritzer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9-18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovulation. The etiology of PCOS is still poorly known, and information from experimental animal models may help improve current understanding of the mechanisms of PCOS initiation and development. Therefore, we conducted a systematic review of currently available methods for simulation of PCOS in experimental models, focusing on two main endocrine traits: ovarian morphology changes and circulating levels of sex hormones and gonadotropins...
February 10, 2017: Reproductive Biology and Endocrinology: RB&E
Samer El Hayek, Lynn Bitar, Layal H Hamdar, Fadi G Mirza, Georges Daoud
Poly Cystic Ovarian Syndrome (PCOS) is one of the most common metabolic and reproductive disorders among women of reproductive age. Women suffering from PCOS present with a constellation of symptoms associated with menstrual dysfunction and androgen excess, which significantly impacts their quality of life. They may be at increased risk of multiple morbidities, including obesity, insulin resistance, type II diabetes mellitus, cardiovascular disease (CVD), infertility, cancer, and psychological disorders. This review summarizes what the literature has so far provided from guidelines to diagnosis of PCOS...
2016: Frontiers in Physiology
Seyedeh Hajar Shahrami, Zahra Abbasi Ranjbar, Forozan Milani, Ehsan Kezem-Nejad, Afagh Hassanzadeh Rad, Seyedeh Fatemeh Dalil Heirat
Critical issue regarding to variation of findings based on different phenotypes led investigators to define whether they are distinct features or overlapping ones. Therefore, we aimed to investigate the association between diverse phenotypes of PCOS (Poly Cystic Ovary Syndrome) with clinical manifestations, anthropometric indices, and metabolic characteristics. This was a descriptive cross-sectional study conducted in 15-39 years old women with PCOS referred to infertility clinics in the north part of Iran, Rasht during 2010-2011...
February 2016: Acta Medica Iranica
Ataollah Ghahiri, Neda Mogharehabed, Mahboobeh Mamourian
BACKGROUND: The purpose of this study was to determine the efficacy and safety of letrozole on ovulation induction and pregnancy in comparison with clomiphene citrate in PCOS patients. MATERIALS AND METHODS: The study was based on prospective randomized clinical trial comparing the efficacy of letrozole as the first-line management of the PCOS patients in comparison to clomiphene citrate during 2009 to 2011 and was performed in one private infertility clinic. The study included 100 patients divided into 2 equal groups...
2016: Advanced Biomedical Research
Mina Zaree, Vahideh Shahnazi, Shabnam Fayezi, Maryam Darabi, Mahzad Mehrzad-Sadaghiani, Masoud Darabi, Sajjad Khani, Mohammad Nouri
BACKGROUND: The omega-3 fatty acid (ω-3 fatty acid) such as eicosapentaenoic acid (EPA) is currently used in the clinic as a nutritional supplement in the treatment of poly- cystic ovarian syndrome (PCOS). The present study was designed to investigate the ef- fect of EPA on the expression levels of peroxisome proliferator-activated receptor gamma (PPARγ) and cytochrome P450 aromatase (encoded by the CYP-19) in primary cultured granulosa cells (GC) from patients undergoing in vitro fertilization (IVF), and also to compare these effects with those in GC of PCOS patients...
July 2015: International Journal of Fertility & Sterility
Hatav Ghasemi Tehrani, Fatemeh Mostajeran, Somayeh Shahsavari
BACKGROUND: Poly cystic ovary syndrome (PCOS) is considered one of the most common endocrine disorders of women in reproductive age. The aim of this study was evaluating the efficacy of calcium and Vitamin D supplementation on the regularity of menstrual cycles, body mass index (BMI) and hyper androgenism state of women with PCOS. MATERIALS AND METHODS: In this clinical trial, 80 women with PCOS were evaluated. They randomly located in four groups receiving metformin (group 1), metformin plus calcium and Vitamin D (group 2), calcium and Vitamin D (group 3) and placebo (group 4) for 4 months...
September 2014: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Fatemeh Sadat Hoseini, Seyed Mohammad Hossein Noori Mugahi, Firoozeh Akbari-Asbagh, Poopak Eftekhari-Yazdi, Behrouz Aflatoonian, Seyed Hamid Aghaee-Bakhtiari, Reza Aflatoonian, Nasser Salsabili
BACKGROUND: The main objective of the present work was to compare the effects of the gonadotropin-releasing hormone agonist (GnRH-a) and GnRH antagonist (GnRH-ant) on the gene expression profiles of oocytes obtained from Iranian infertile couples undergoing in vitro fertilization (IVF). METHODS: Fifty infertile couples who underwent IVF between June 2012 and November 2013 at the Infertility Center of Tehran Women General Hospital, Tehran University of Medical Sciences, were included in this study...
2014: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
P Saikumar, Vs Kalai Selvi, K Prabhu, Prasana Venkatesh, Prashanth Krishna
BACKGROUND: Polycystic ovarian disease is one of the most common causes of infertility in women of reproductive age. Anti- mullerian hormone (AMH), a member of transforming growth factor (TGF) family which is secreted by granulosa cells of growing follicle, is found to be increased to three to four fold in Poly Cystic Ovarian Syndrome (PCOS) patients as evidenced by previous studies. But the level of AMH in relation to the infertile status of PCOS was not studied yet. The present study was focused to determine the discriminative power of AMH in infertility subjects with regular cycles and infertility subjects associated with PCOS...
September 2013: Journal of Clinical and Diagnostic Research: JCDR
S A Dayani Siriwardene, L P A Karunathilaka, N D Kodituwakku, Y A U D Karunarathne
Poly Cystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, resulting from insulin resistance and the compensatory hyperinsulinemia. This results in adverse effect on multiple organ systems and may result in alteration in serum lipids, anovulation, abnormal uterine bleeding and infertility. According to Ayurvedic view PCOS can be correlated with Aarthava Kshaya. It was revealed that most of subfertility patients who were presented Osuki Ayurveda Centre suffered from the PCOS...
January 2010: Ayu
M K C Nair, Princly Pappachan, Sheila Balakrishnan, M L Leena, Babu George, Paul S Russell
OBJECTIVE: To study the clinical outcome after a gap of 2 years, among adolescent girls with confirmed menstrual irregularity and with or without ultrasound diagnosed polycystic ovaries. METHODS: 136 adolescent girls from a cohort of 301 girls between 15 and 17 years of age with confirmed menstrual irregularity, with or without ultrasound diagnosed polycystic ovaries, were assessed in detail after a gap of 2 years. Present menstrual history and symptoms as well as signs of polycystic ovary syndrome (PCOS) were recorded, apart from ultrasound scanning of abdomen...
January 2012: Indian Journal of Pediatrics
Caroline A Smith, Bridget Carmady
BACKGROUND: Women specific health complaints are common, and women are higher users of complementary therapies and medicines. Acupuncture is one modality used by women. The aim of this paper was to summarise the evidence from scientific trials and systematic reviews assessing the effectiveness of acupuncture to treat the most common women specific reproductive health complaints. METHODS: We conducted a search of the major databases PubMed, CINAHL, and the Cochrane Library from their inception to Sept 2009, to obtain English language texts of randomised controlled trials (RCTs) and systematic reviews...
October 28, 2010: Autonomic Neuroscience: Basic & Clinical
Rachid Khemakhem, Amel Barhoumi, Nadia Matoussi, Saida Hidouri, Sofiane Ghorbel, Faouzi Nouira, Said Jlidi, Saida Ben Becheur, Béji Chaouachi
BACKGROUND: Adnexal torsion is the most frequent gynaecological emergency in children. It requires an early diagnosis and an urgent surgical treatment. PURPOSE: to study the clinical, paraclinical and therapeutic aspect of adnexal torsion in paediatric population. METHODS: This is a retrospective review of nine girls with the diagnosis of ovarian torsion observed over a 7 years period (January 1999 to December 2005). RESULTS: The average age is 9 years (extreme 6 to 13 years)...
May 2008: La Tunisie Médicale
Aziz-un-Nisa Abbasi, Anwar Sultana, Raeesa Izhar, Shamshad Begum, Sadia Razaq
BACKGROUND: This study was carried out to determine the effectiveness and safety of minilaparotomy and ovarian drilling for sub fertile women with clomiphene resistant polycystic ovarian syndrome. METHODS: During a 2 year period (August 2000 to August 2002) 16 patients with polycystic ovarian disease were managed by minilaparotomy and ovarian drilling by diathermy. All the patients underwent full infertility workup and then treated with cyclical clomiphene citrate for 6 months...
October 2003: Journal of Ayub Medical College, Abbottabad: JAMC
W Futterweit, L Deligdisch
The effects of exogenously administered testosterone were evaluated in a group of 19 female to male transsexuals who underwent bilateral salpingo-oophorectomy after a variable period of androgen therapy. The findings were compared to those in an age-matched group of 12 patients who underwent pelvic surgery for nonendocrine reasons. The most significant findings in the 19 androgen-treated female transsexuals was the finding of enlarged or borderline enlarged ovaries in 5 subjects. In addition, we found multiple cystic follicles in 17 patients (89...
January 1986: Journal of Clinical Endocrinology and Metabolism
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