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https://www.readbyqxmd.com/read/29029231/analysis-of-phylogenomic-tree-space-resolves-relationships-among-marsupial-families
#1
David A Duchêne, Jason G Bragg, Sebastián Duchêne, Linda E Neaves, Sally Potter, Craig Moritz, Rebecca N Johnson, Simon Y W Ho, Mark D B Eldridge
A fundamental challenge in resolving evolutionary relationships across the Tree of Life is to account for heterogeneity in the evolutionary signal across loci. Studies of marsupial mammals have demonstrated that this heterogeneity can be substantial, leaving considerable uncertainty in the evolutionary timescale and relationships within the group. Using simulations and a new phylogenomic data set comprising nucleotide sequences of 1550 loci from 18 of the 22 extant marsupial families, we demonstrate the power of a method for identifying clusters of loci that support different phylogenetic trees...
September 22, 2017: Systematic Biology
https://www.readbyqxmd.com/read/29028250/comprehensive-biological-monitoring-to-assess-isocyanates-and-solvents-exposure-in-the-nsw-australia-motor-vehicle-repair-industry
#2
Jimmy Hu, Phillip Cantrell, Aklesh Nand
Urethane products that contain isocyanates are extensively used in the motor vehicle repair (MVR) industry and other industries such as furniture and cabinet-making as two-pack spray paints, clears, and adhesives. Attention has recently been refocussed on isocyanate-containing chemicals, particularly in paints. The spray painters in the MVR industry had a propensity to develop industrial asthma at a rate 80 times higher than the general public, which was previously reported in the UK. To track workers exposure to isocyanates, urine samples were collected from 196 spray painters who worked mainly in 78 MVR shops across 54 New South Wales (NSW) towns and suburbs...
October 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29027529/-twin-pregnancy-with-complete-hydatidiform-mole
#3
I N Voloshchuk, I V Barinova, N I Kondrikov, R A Barto
The paper describes a case of twin pregnancy with complete hydatidiform mole (CHM). According to the data available in the literature, the concurrence of CHM with a normal placenta and a viable fetus occurs in 1 per 20,000-100,000 pregnancies, requires a differential diagnosis with partial hydatidiform mole and placental mesenchymal dysplasia, and is characterized by a high rate of complications. In this concurrence, the frequency of persistent trophoblastic disease is as high as 50%. In this case, the pregnancy ended in a spontaneous abortion at 16-17 weeks of pregnancy...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/29027457/gravimetric-standard-gas-mixtures-for-global-monitoring-of-atmospheric-sf6
#4
Jeong Sik Lim, Jinbok Lee, Dongmin Moon, Jin Seog Kim, Jeongsoon Lee, Bradley D Hall
In this study, standard gas mixtures of SF6 in synthetic air were gravimetrically developed as a suite consisting of 6 mixtures with mole fractions of SF6 ranging from 5 to 15 pmol/mol. For precision in weighing the gas fills, an automatic weighing system coupled with a high sensitivity mass balance was used and a gravimetry precision of 3 mg (2σ) was achieved. Impurity profiles of the raw gases were determined by various analyzers. In particular, sub pmol/mol levels of SF6 in the matrix components (N2, O2, and Ar) were carefully measured, since the mole fraction of SF6 in the final step can be significantly biased by this trace amount of SF6 in the raw gases of the matrix components...
October 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29027092/toxic-effects-of-oxytetracycline-and-copper-separately-or-combined-on-soil-microbial-biomasses
#5
Lanjun Wang, Jinhua Wang, Lusheng Zhu, Jun Wang
The production of commercial livestock and poultry often involves using with antibiotics and feed additives, such as oxytetracycline (OTC) and copper (Cu). These are often excreted into the soil by animal feces; hence, combined pollutants may contaminate the soil. To evaluate single and combined toxic effects of OTC and Cu on the soil ecology, changes in quantities of bacteria, fungi, and actinomycetes in the soil were studied over a 28-d incubation period by a plate count method, microbes numbers counted on days 7, 14, 21, and 28...
October 12, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29026012/the-orbiting-carbon-observatory-2-early-science-investigations-of-regional-carbon-dioxide-fluxes
#6
A Eldering, P O Wennberg, D Crisp, D S Schimel, M R Gunson, A Chatterjee, J Liu, F M Schwandner, Y Sun, C W O'Dell, C Frankenberg, T Taylor, B Fisher, G B Osterman, D Wunch, J Hakkarainen, J Tamminen, B Weir
NASA's Orbiting Carbon Observatory-2 (OCO-2) mission was motivated by the need to diagnose how the increasing concentration of atmospheric carbon dioxide (CO2) is altering the productivity of the biosphere and the uptake of CO2 by the oceans. Launched on 2 July 2014, OCO-2 provides retrievals of the column-averaged CO2 dry-air mole fraction ([Formula: see text]) as well as the fluorescence from chlorophyll in terrestrial plants. The seasonal pattern of uptake by the terrestrial biosphere is recorded in fluorescence and the drawdown of [Formula: see text] during summer...
October 13, 2017: Science
https://www.readbyqxmd.com/read/29025871/audiograms-of-three-subterranean-rodent-species-gen-fukomys-determined-by-auditory-brainstem-responses-reveal-extremely-low-high-frequency-cut-offs
#7
Patricia Gerhardt, Yoshiyuki Henning, Sabine Begall, E Pascal Malkemper
Life underground has shaped the auditory sense of subterranean mammals, shifting their hearing range to low frequencies. Mole-rats of the genus Fukomys have, however, been suggested to hear up to 18.5 kHz, unusually high for a subterranean rodent. We present audiograms of three mole-rat species, Fukomys anselli, Fukomys micklemi and the giant mole-rat Fukomys mechowii, based on evoked auditory brainstem potentials. All species showed low sensitivity and restricted hearing ranges at 60 dB SPL extending from 125 Hz to 4 kHz (5 octaves) with most sensitive hearing between 0...
October 12, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29025264/b-n-b-bond-embedded-phenalenyl-and-its-anions
#8
Haipeng Wei, Yulan Liu, Tullimilli Y Gopalakrishna, Hoa Phan, Xiaobo Huang, Lipiao Bao, Jing Guo, Jun Zhou, Shenglian Luo, Jishan Wu, Zebing Zeng
Despite the great potential of heteroatom-contained polycyclic aromatic hydrocarbons in organic optoelectronics, there are very limited reports on hetero-aromatics containing B-N-B bond in the π-scaffold. Herein, stable 1,9-dibora-9a-azaphenalenyl (DBAP) derivatives, named as BNB-embedded phenalenyls, are presented. The DBAP skeleton contains a three-center two-π-electron B-N-B moiety with total 12 π-electrons and can be regarded as the isoelectronic structure of phenalenyl cation. Chemical reduction of the phenyl derivative of DBAP by potassium generated the dianion containing 14 delocalized π-electrons, which can be regarded as isoelectronic structure of phenalenyl anion...
October 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29025247/molecular-and-histological-characteristics-of-early-triploid-and-partial-molar-pregnancies
#9
Katerina Kubelka-Sabit, Dzengis Jasar, Vanja Filipovski, Gorgi Bozinovski, Dijana Plaseska-Karanfilska
Molar pregnancy has the highest incidence of all gestational trophoblastic diseases. This is a heterogeneous group of diseases, composed of precancerous lesions and gestational trophoblastic tumours. The hydatidiform mole is characterised by varying degrees of proliferation of syncytiotrophoblastic and cytotrophoblastic cells and stromal oedema. Based on established morphological and cytogenetic criteria, molar pregnancy is divided into partial and complete. The risk of persistent trophoblastic disease is higher in complete moles compared with partial moles...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/29023082/be-vigilant-for-skin-manifestations-of-inherited-cancer-syndromes
#10
Alice SM Tidman
More than 200 hereditary cancer susceptibility syndromes have been described, and it is thought that they account for 5-10% of all cancers. Many have dermatological manifestations (usually lesions, occasionally rashes) which frequently precede other systemic pathology. Dermatological signs are usually non-specific and often trivial in appearance, making their significance easy to overlook and a clinical diagnosis challenging. Histological examination is often required to differentiate lesions. They are usually benign and pathologically unrelated to the primary tumours, with the exception of the atypical moles of the dysplastic naevus syndrome, and may present simply as a cosmetic problem for the patient...
January 2017: Practitioner
https://www.readbyqxmd.com/read/29022695/high-activity-and-convenient-ratio-control-dna-directed-coimmobilization-of-multiple-enzymes-on-multifunctionalized-magnetic-nanoparticles
#11
Ye Yang, Ruiqi Zhang, Bingnan Zhou, Jiayi Song, Ping Su, Yi Yang
The development of new methods for fabricating artificial multienzyme systems has attracted much interest because of the potential applications and the urgent need for multienzyme catalysts. Controlling the enzyme ratio is critical for improving the cooperative enzymatic activity in multienzyme systems. Herein, we introduce a versatile strategy for fabricating a multienzyme system by coimmobilizing horseradish peroxidase (HRP) and glucose oxidase (GOx) on magnetic nanoparticles multifunctionalized with dopamine derivatives through DNA-directed immobilization...
October 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29020788/-complete-molar-pregancy-with-development-of-non-metastatic-persistent-trophoblastic-diseasea-case-report-reflection-of-rules-of-care-and-decision-making-processes-forensic-responsibility-and-the-position-of-doctor-in-the-general-gynecologic-and-obstetric-outpatient
#12
S Zeman, P Trávník, K Dvořáková, J Zemanová
OBJECTIVE: To define the forensic responsibility and the position of doctor in the general gynecologic and obstetric outpatient practice in care of the complete molar pregancy. DESIGN: Case report and review article. SETTING: General gynecologic and obstetric outpatient practice Velké Meziříčí; Sanatorium REPROMEDA, Centre of reproductive medicine and preimplantation genetics, Brno; Histopatology department of Hospital Jihlava. CASE REPORT: The changing clinical presentation of complete molar pregnancy with development of non-metastatic gestational trophoblastic disease: management...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29020051/a-combination-of-plasma-phospholipid-fatty-acids-and-its-association-with-incidence-of-type-2-diabetes-the-epic-interact-case-cohort-study
#13
Fumiaki Imamura, Stephen J Sharp, Albert Koulman, Matthias B Schulze, Janine Kröger, Julian L Griffin, José M Huerta, Marcela Guevara, Ivonne Sluijs, Antonio Agudo, Eva Ardanaz, Beverley Balkau, Heiner Boeing, Veronique Chajes, Christina C Dahm, Courtney Dow, Guy Fagherazzi, Edith J M Feskens, Paul W Franks, Diana Gavrila, Marc Gunter, Rudolf Kaaks, Timothy J Key, Kay-Tee Khaw, Tilman Kühn, Olle Melander, Elena Molina-Portillo, Peter M Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, Salvatore Panico, Olov Rolandsson, Sabina Sieri, Carlotta Sacerdote, Nadia Slimani, Annemieke M W Spijkerman, Anne Tjønneland, Rosario Tumino, Yvonne T van der Schouw, Claudia Langenberg, Elio Riboli, Nita G Forouhi, Nick J Wareham
BACKGROUND: Combinations of multiple fatty acids may influence cardiometabolic risk more than single fatty acids. The association of a combination of fatty acids with incident type 2 diabetes (T2D) has not been evaluated. METHODS AND FINDINGS: We measured plasma phospholipid fatty acids by gas chromatography in 27,296 adults, including 12,132 incident cases of T2D, over the follow-up period between baseline (1991-1998) and 31 December 2007 in 8 European countries in EPIC-InterAct, a nested case-cohort study...
October 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29020036/mixtures-of-tense-and-relaxed-state-polymerized-human-hemoglobin-regulate-oxygen-affinity-and-tissue-construct-oxygenation
#14
Donald Andrew Belcher, Uddyalok Banerjee, Christopher Michael Baehr, Kristopher Emil Richardson, Pedro Cabrales, François Berthiaume, Andre Francis Palmer
Pure tense (T) and relaxed (R) quaternary state polymerized human hemoglobins (PolyhHbs) were synthesized and their biophysical properties characterized, along with mixtures of T- and R-state PolyhHbs. It was observed that the oxygen affinity of PolyhHb mixtures varied linearly with T-state mole fraction. Computational analysis of PolyhHb facilitated oxygenation of a single fiber in a hepatic hollow fiber (HF) bioreactor was performed to evaluate the oxygenation potential of T- and R-state PolyhHb mixtures...
2017: PloS One
https://www.readbyqxmd.com/read/29018488/higher-resting-metabolic-rate-in-long-lived-breeding-ansell-s-mole-rats-fukomys-anselli
#15
Charlotte Katharina Maria Schielke, Hynek Burda, Yoshiyuki Henning, Jan Okrouhlík, Sabine Begall
BACKGROUND: Reproduction is an energetically expensive process that supposedly impairs somatic integrity in the long term, because resources are limited and have to be allocated between reproduction and somatic maintenance, as predicted by the life history trade-off model. The consequence of reduced investment in somatic maintenance is a gradual deterioration of function, i.e. senescence. However, this classical trade-off model gets challenged by an increasing number of contradicting studies...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/29016108/vanadium-redox-flow-batteries-using-meta-polybenzimidazole-based-membranes-of-different-thicknesses
#16
Chanho Noh, Mina Jung, Dirk Henkensmeier, Suk Woo Nam, Yongchai Kwon
15, 25, and 35 μm thick meta-polybenzimidazole (PBI) membranes are doped with H2SO4 and tested in a vanadium redox flow battery (VRFB). Their performances are compared with those of Nafion membranes. Immersed in 2 M H2SO4, PBI absorbs about 2 mol of H2SO4 per mole of repeat unit. This results in low conductivity and low voltage efficiency (VE). In ex-situ tests, meta-PBI shows a negligible crossover of V(3+) and V(4+) ions, much lower than that of Nafion. This is due to electrostatic repulsive forces between vanadium cations and positively charged protonated PBI backbones, and the molecular sieving effect of PBI's nanosized pores...
October 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28992307/attempted-molecular-detection-of-the-thermally-dimorphic-human-fungal-pathogen-emergomyces-africanus-in-terrestrial-small-mammals-in-south-africa
#17
Nadine Cronjé, Ilan S Schwartz, Liezl Retief, Armanda D S Bastos, Sonja Matthee, Wolfgang Preiser, Nigel C Bennett, Tsidiso Maphanga, Nelesh P Govender, Robert Colebunders, Chris Kenyon
The ecological niche of Emergomyces africanus (formerly Emmonsia species), a dimorphic fungus that causes an AIDS-related mycosis in South Africa, is unknown. We hypothesized that natural infection with E. africanus occurs in wild small mammals. Using molecular detection with primers specific for E. africanus, we examined 1402 DNA samples from 26 species of mole-rats, rodents, and insectivores trapped in South Africa that included 1324 lung, 37 kidney, and 41 liver specimens. DNA of E. africanus was not detected in any animals...
September 9, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28989827/recovery-of-volatile-fatty-acids-from-fermented-wastewater-by-adsorption
#18
Ehsan Reyhanitash, Sascha R A Kersten, Boelo Schuur
Separation of volatile fatty acids (VFAs) from fermented wastewater is challenging, due to low VFA concentrations in mineral-rich streams. As a result, separation capacity and selectivity with traditional solvents and adsorbents are both compromised. In this study, using a complex artificial model solution mimicking real fermented wastewaters, it is shown that a simple and robust adsorption-based separation technique can retain a remarkable capacity and selectivity for VFAs. Four types of polystyrene-divinylbenzene-based resins (primary, secondary, and tertiary amine-functionalized, and nonfunctionalized) were examined as the adsorbents...
October 2, 2017: ACS Sustainable Chemistry & Engineering
https://www.readbyqxmd.com/read/28989763/into-the-dark-patterns-of-middle-ear-adaptations-in-subterranean-eulipotyphlan-mammals
#19
Daisuke Koyabu, Misato Hosojima, Hideki Endo
Evolution of the middle ear ossicles was a key innovation for mammals, enhancing the transmission of airborne sound. Radiation into various habitats from a terrestrial environment resulted in diversification of the auditory mechanisms among mammals. However, due to the paucity of phylogenetically controlled investigations, how middle ear traits have diversified with functional specialization remains unclear. In order to identify the respective patterns for various lifestyles and to gain insights into fossil forms, we employed a high-resolution tomography technique and compared the middle ear morphology of eulipotyphlan species (moles, shrews and hedgehogs), a group that has radiated into various environments, such as terrestrial, aquatic and subterranean habitats...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28985606/preparation-of-artificial-red-cell-and-its-application-on-alleviation-of-tumor-hypoxia
#20
Jiaxin Qu, Xiaomeng Guo, Wei Li, Wanqing Hou, Hanbo Zhang, Lihua Luo, Chunqi Zhu, Jie Yang, Xiaoyi Yin, Yuan Tao, Yongzhong Du, Yan Lou, Dawei Chen, Jian You
Hemoglobin-based oxygen carriers were developed as an alternative for blood transfusion. However, the research progress for their further clinic applications was slow in recent several years. Hypoxia is found in most solid tumors, which is responsible for the tumor formation, increased metastasis, drug resistance during therapeutic process as well as poor patient survival. In this work, novel hemoglobin (Hb) loaded nanoliposomes, as artificial red cells for oxygen delivery, were optimized by screening various types of phospholipids and analyzing different mole ratio of phospholipid to cholesterol...
September 20, 2017: Colloids and Surfaces. B, Biointerfaces
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