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https://www.readbyqxmd.com/read/28727666/arthropathies-in-inflammatory-bowel-disease-a-review-for-clinicians
#1
Jeremy Wiens, James A Rankin, Karen L Then
Inflammatory bowel disease (IBD) is a systemic, chronic autoimmune disease of the digestive tract. The etiology and pathophysiology of IBD is not fully understood, though it is believed to be due to a complex interaction among the patient's genotype, immune system, and environmental factors. Inflammatory bowel disease is frequently accompanied by extraintestinal manifestations that occur in almost half of all patients. The most common extraintestinal manifestation that occurs is joint disease, collectively termed the arthropathies of IBD...
July 19, 2017: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/28724345/simultaneous-bilateral-total-knee-arthroplasty-in-hemophilia-is-it-recommended
#2
E Carlos Rodriguez-Merchan
Simultaneous bilateral total knee arthroplasty (TKA) is a potentially cost-saving manner of caring for patients with hemophilia who have bilateral symptomatic hemophilic knee arthropathy. Because factor VIII is used only once in bilateral TKA, it is performed in hemophilia to reduce costs. Areas covered: This article reviews the potential role of simultaneous bilateral TKA in patients with hemophilia. Expert commentary: Although two recent reports have mentioned the benefits of simultaneous bilateral TKA in patients with hemophilia, the data are still scant and preliminary...
July 20, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28722831/a-new-wave-in-the-evaluation-of-haemophilic-arthropathy
#3
N Bakeer
No abstract text is available yet for this article.
July 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28722821/sensory-strategies-of-postural-sway-during-quiet-stance-in-patients-with-haemophilic-arthropathy
#4
C Cruz-Montecinos, C De la Fuente, G Rivera-Lillo, S Morales-Castillo, V Soto-Arellano, F Querol, S Pérez-Alenda
INTRODUCTION: The sensory strategies of postural control in adult haemophilic arthropathy patients are still poorly understood. AIM: To determine sensorial posture-control strategies through postural sway frequency analysis when in a bipedal quiet stance with and without visual stimulus deprivation in healthy subjects and patients with haemophilic arthropathy. Secondarily, to determine the irregularity of postural balance control through sample entropy (SampEn)...
July 19, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28721679/phytochemicals-as-potential-antidotes-for-targeting-nf-%C3%AE%C2%BAb-in-rheumatoid-arthritis
#5
REVIEW
R Kowshik Aravilli, S Laveen Vikram, V Kohila
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune destructive arthropathy prevalent among people in the age group of 40-70 years. RA induces severe pain, swelling and stiffness of joints resulting in bone damage. RA leads to reduced life expectancy when left untreated. RA is characterized by synovial hyperplasia, infiltration of inflammatory cells resulting in formation of pannus. Synovial hyperplasia is mediated by proinflammatory cytokines, notably IL-1 and TNF-α. NF-κB is a predominant transcription factor in amplifying the inflammatory response...
August 2017: 3 Biotech
https://www.readbyqxmd.com/read/28719991/the-diagnostic-utility-and-clinical-implications-of-wrist-mri-in-the-pediatric-population
#6
Alex L Gornitzky, Ines C Lin, Robert B Carrigan
BACKGROUND: Unexplained wrist pain is a common presentation in children. To our knowledge, no studies have explored the clinical utility of magnetic resonance imaging (MRI) in the diagnostic workup of pediatric patients. METHODS: We retrospectively reviewed 307 consecutive wrist MRIs ordered at a tertiary-care pediatric hospital. Demographic data and the indication for imaging were recorded and grouped into admitting categories. The final impression of each MRI was scored with regard to potential impact on future treatment (0 = normal, 1 = minimal, 2 = moderate, 3 = high)...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28718589/-drug-induced-iatrogenic-arthropathies
#7
Pascal Zufferey
Arthropathies induced by drugs, especially arthralgias, are very frequently reported in pharmacology. The major difficulty often consists in confirming the accountability of the drug in the occurrence of the symptoms. Stopping the drug when it really responsible of the arthralgia is then likely to lead to the disappearance of the symptoms. The aim of this article is to review some of classical known induced arthropathies and some innovations by describing the clinical characteristics as well as the mechanisms linking the drug to the arthropathies when these have been clarified...
March 8, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28716862/gene-therapy-for-wiskott-aldrich-syndrome-in-a-severely-affected-adult
#8
Emma C Morris, Thomas Fox, Ronjon Chakraverty, Rita Tendeiro, Katie Snell, Christine Rivat, Sarah Grace, Kimberly Gilmour, Sarita Workman, Karen Buckland, Katie Butler, Ronnie Chee, Alan D Salama, Hazem Ibrahim, Havinder Hara, Cecile Duret, Fulvio Mavilio, Frances Male, Frederick D Bushman, Anne Galy, Siobhan O Burns, H Bobby Gaspar, Adrian J Thrasher
Until recently hematopoietic stem cell transplantation was the only curative option for Wiskott-Aldrich syndrome (WAS). The first attempts at gene therapy for WAS using a ϒ-retroviral vector improved immunological parameters substantially but were complicated by acute leukemia as a result of insertional mutagenesis in a high proportion of patients. More recently treatment of children with a state-of-the-art self-inactivating lentiviral vector (LV-w1.6 WASp) has resulted in significant clinical benefit without inducing selection of clones harbouring integrations near oncogenes...
July 17, 2017: Blood
https://www.readbyqxmd.com/read/28709759/total-hip-arthroplasty-outcomes-an-18-year-experience-in-a-single-center-is-systemic-lupus-erythematosus-a-potential-risk-factor-for-adverse-outcomes
#9
Javier Merayo-Chalico, Marco Gónzalez-Contreras, Rigoberto Ortíz-Hernández, Jorge Alcocer-Varela, David Marcial, Diana Gómez-Martín
BACKGROUND: In patients with systemic lupus erythematosus (SLE), persistent joint activity and treatment with glucocorticoids are associated with musculoskeletal complications. About 30% of these patients become candidates for surgical treatment. The aim of this study was to evaluate postoperative outcomes after total hip arthroplasty (THA) in SLE patients. METHODS: We performed a retrospective cohort study at a tertiary care center in Mexico City between 1995 and 2013...
June 19, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28706846/arthroscopic-reduction-and-fixation-of-transverse-intra-articular-glenoid-fractures-with-scapular-extension
#10
Anastasios Papadonikolakis
The most common procedure to address transverse glenoid fractures that are characterized by intra-articular step-off or gapping is open reduction and internal fixation. Disadvantages of open surgery are delay in regaining full range of motion, increased approach morbidity, neurovascular complications, and the need for capsulotomy, which delays healing and increases the risk of stiffness. An arthroscopically assisted fracture fixation, as described in this article, is characterized by better visualization of the glenoid articular surface and reduction of the intra-articular fragments under direct vision, which diminishes the chances of residual step-off after fixation...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28705372/cross-sectional-imaging-for-inflammatory-arthropathy-of-the-pelvis
#11
Ali Alian, Hythem Omar, Avneesh Chhabra
Inflammatory arthropathy predominantly affecting the axial skeleton can cause pain, stiffness, disability, and ankylosis. This article discusses the use of cross-sectional imaging in the domain of inflammatory pelvic and axial arthropathy highlighting the key distinguishing features of common known diseases and their differential diagnoses.
June 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/28704747/two-cases-of-late-medial-instability-of-the-knee-due-to-hip-disease-after-total-knee-arthroplasty
#12
Masanori Tsubosaka, Tomoyuki Matsumoto, Koji Takayama, Naoki Nakano, Ryosuke Kuroda
INTRODUCTION: There are few specific reports of late medial instability after total knee arthroplasty (TKA). We described two cases of late medial instability of the knee due to hip disease with osteoarthritis or rheumatoid arthritis after TKA, which required revision TKA. PRESENTATION OF CASES: An 82-year-old woman experienced right femoral neck fracture due to a fall that required conservative treatment at age 77 years and underwent left TKA at age 80 years. A 68-year-old woman underwent left TKA at age 54 years, right TKA at age 64 years, and left THA at age 67 years...
June 29, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28704245/inciting-events-associated-with-lumbar-facet-joint-pain
#13
Charles A Odonkor, Yian Chen, Peju Adekoya, Bryan J Marascalchi, Hira Chaudhry-Richter, Teresa Tang, Christopher Abruzzese, Berklee K Cohen, Steven P Cohen
BACKGROUND: Low back pain is the leading cause of years lost to disability with approximately 15%-25% of the chronic back pain population suffering from lumbar facet arthropathy. No large-scale study has sought to systematically identify inciting events for lumbar facet arthropathy. The aim of this study is to quantify the proportion of individuals with lumbar facetogenic pain who report a specific precipitating event(s) and to determine if there is a correlation between these events and treatment outcome...
July 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28699404/improved-external-rotation-with-concomitant-reverse-total-shoulder-arthroplasty-and-latissimus-dorsi-tendon-transfer-a-systematic-review
#14
Aaron Wey, John C Dunn, Nicholas Kusnezov, Brian R Waterman, Kelly G Kilcoyne
BACKGROUND: In conjunction with reverse total shoulder arthroplasty (RSA), latissimus dorsi and teres major (LD-TM) transfer has been advocated in the setting of combined loss of elevation and external rotation. The purpose of this systematic review is to summarize the clinical outcomes following RSA with LD-TM transfer. METHODS: A search of PubMed, EMBASE, CINAHL, Medline, and Cochrane databases was performed between January 1, 1990 and March 1, 2016 and included articles related to outcomes following RSA with LD-TM transfer...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28696850/advanced-mr-imaging-techniques-for-differentiation-of-neuropathic-arthropathy-and-osteomyelitis-in-the-diabetic-foot
#15
Teodoro Martín Noguerol, Antonio Luna Alcalá, Luis S Beltrán, Marta Gómez Cabrera, Jordi Broncano Cabrero, Joan C Vilanova
Diagnosis and treatment of foot disease in patients with diabetes is a common clinical-radiologic challenge, particularly the differentiation of neuropathic arthropathy from osteomyelitis. Conventional clinical tests and imaging techniques have limited accuracy for evaluation of the diabetic foot. The introduction of morphologic magnetic resonance (MR) imaging in these patients has provided a qualitative leap in diagnosis. The characteristics of soft-tissue and bone marrow edema and their patterns of distribution throughout the foot allow discrimination between both entities...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28692451/the-value-of-musculoskeletal-ultrasound-in-geriatric-care-and-rehabilitation
#16
Büşra Can, Murat Kara, Özgür Kara, Zekeriya Ülger, Walter Frontera, Levent Özçakar
The WHO reports that one of the major chronic conditions affecting the elderly worldwide is musculoskeletal disorders that are associated with long-term pain and disability. Considering the healthcare needs of the elderly (i.e. comprehensive, accessible, efficient) and the advantages of ultrasound (US) use (patient-friendly, convenient, cost-effective, and does not require exposure to radiation or magnetic fields), there seems to be a 'gap' in the actual clinical practice. In this paper, we aimed to highlight the potential value of US imaging in the management of the elderly with a wide spectrum of musculoskeletal conditions (degenerative/rheumatic joint diseases, falls/trauma, nursing care, peripheral nerve problems, sarcopenia, and interventions)...
July 7, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28689929/serum-c-reactive-protein-in-patients-undergoing-elective-shoulder-arthroplasty-prospective-study
#17
Carlos Torrens, Fernando Santana, Raquel Marí, Lluis Puig, Albert Alier
BACKGROUND: The objective of the study was to determine the normalization curve of the serum C-reactive protein (CRP) in elective shoulder arthroplasty. METHODS: A prospective study including 58 consecutive patients who had undergone elective shoulder arthroplasty. Forty-one patients had received a Reverse Shoulder Arthroplasty, 13 a Total Shoulder Arthroplasty and 4 a Hemiarthroplasty. Based on a pilot study, blood samples to determine CRP values were obtained at baseline (1 h before surgery), on the 1st, 2nd, 6th, 8th and 14th postoperative days...
July 7, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28689820/reverse-total-shoulder-glenoid-baseplate-stability-with-superior-glenoid-bone-loss
#18
Elise J Martin, Thomas R Duquin, Mark T Ehrensberger
BACKGROUND: Superior wear of the glenoid bone is common in patients with rotator cuff arthropathy. This can become a treatment challenge for patients who require shoulder arthroplasty. In reverse shoulder arthroplasty (RSA), glenoid bone loss may affect the stability of baseplate fixation. The primary purpose of this biomechanical laboratory study was to assess the initial fixation stability of RSA glenosphere baseplates in the presence of variable amounts of superior glenoid bone loss...
July 6, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28689372/deficits-of-ankle-muscle-strength-not-found-in-children-adolescents-and-young-adults-with-haemophilic-ankle-arthropathy
#19
S Lobet, J-L Croisier, A-C Lantin, C Hermans, K Peerlinck, J Vandesande, J-B Pialat, K Deschamps
OBJECTIVES: Adequate management of haemophilia patients requires early detection of joint impairment in relatively asymptomatic patients. This study sought to quantify the impact of the ankle's structural impairment on muscle strength in children, adolescent and young adults with haemophilia (CAAwH). METHODS: Twenty-three CAAwH underwent bilateral magnetic resonance imaging (MRI) assessing the anatomical status of tibiotalar joint (TTJ) and subtalar joint (STJ) using the International Prophylaxis Study Group MRI scale...
July 9, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28689367/rapidly-progressive-osteoarthritis-a-review-of-the-clinical-and-radiologic-presentation
#20
REVIEW
Donald J Flemming, Cristy N Gustas-French
PURPOSE OF REVIEW: The purpose of this paper is to review the distinct clinical and radiographic features that may lead to prompt diagnosis of rapidly progressive osteoarthritis (RPOA) and thus obviate unnecessary and costly diagnostic workup. RECENT FINDINGS: RPOA is uncommon but is more frequently seen in practice because of the aging population. RPOA is a destructive arthropathy that occurs most commonly in elderly women but can also be seen in patients that have sustained trauma...
July 2017: Current Rheumatology Reports
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