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https://www.readbyqxmd.com/read/28920485/the-use-of-soft-tissue-expanders-prior-to-total-ankle-arthroplasty
#1
Ameya V Save, Daniel H Wiznia, Mike Wang, Chang-Yeon Kim, John S Reach
Soft tissue coverage and tension-free closure can often be challenging in patients with ankle arthropathy being considered for total ankle arthroplasty. We present 2 patients with severe posttraumatic ankle arthropathy who underwent placement of a soft tissue expander to assist with soft tissue coverage prior to total ankle arthroplasty. LEVELS OF EVIDENCE: Level IV.
October 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28914369/joint-involvement-in-mexican-patients-with-ulcerative-colitis-a-hospital-based-retrospective-study
#2
Jesús K Yamamoto-Furusho, Andrea Sarmiento-Aguilar
The most frequent extra-intestinal manifestation in ulcerative colitis (UC) around the world is joint involvement. There are no previous data in Latin America that is about this aspect of disease; hence, the aim of this study was to determine the frequency and factors associated to joint involvement in Mexican patients with UC. A total of 295 patients with histological diagnosis of UC were studied, divided into two groups: (1) 154 cases with at least one joint affection (arthralgia, peripheral, or axial arthropathy (sacroilitis (SI) or ankylosing spondylitis (AS))) and (2) 141 controls that had never presented any joint involvement during the clinical course of UC...
September 15, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28912633/a-preliminary-case-series-evaluating-the-safety-and-immediate-to-short-term-clinical-benefits-of-joint-mobilization-in-hemophilic-arthritis-of-the-lower-limb
#3
Emma Scaddan, John Rowell, Shaun O'Leary
OBJECTIVES: Arthritis resulting from recurrent intra-articular bleeding in individuals with hemophilia can be severely debilitating due to joint pain and stiffness with subsequent loss of mobility and function. Very limited studies have investigated the potential benefits of joint mobilization for this condition. This case series is a preliminary investigation of safety, as well as immediate and short-term clinical benefits, associated with gentle knee and ankle joint mobilization in people with hemophilic arthropathy...
September 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28912620/hormonal-contraception-and-the-development-of-autoimmunity-a-review-of-the-literature
#4
William V Williams
Estrogens and progestins are known to have profound effects on the immune system and may modulate the susceptibility to autoimmune diseases. A comprehensive literature search was carried out using PubMed for any of 153 autoimmune disease terms and the terms contraception, contraceptive, or their chemical components with limits of Humans + Title or Abstract. Over 1,800 titles were returned and scanned, 352 papers retrieved and reviewed in depth and an additional 70 papers retrieved from the bibliographies. Based on this review, substantial evidence exists linking the use of combined oral contraceptives to a lower incidence of hyperthyroidism, an increase in multiple sclerosis, ulcerative colitis, Crohn's disease, Systemic Lupus Erythematosus, and interstitial cystitis...
August 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28911814/the-effect-of-patient-gender-on-outcomes-after-reverse-total-shoulder-arthroplasty
#5
Stephanie E Wong, Austin A Pitcher, David Y Ding, Nicola Cashman, Alan L Zhang, C Benjamin Ma, Brian T Feeley
BACKGROUND: Gender differences may exist for patients undergoing shoulder arthroplasty. Limited data suggest that women may have worse preoperative disability and outcomes. Our objective was to determine whether gender influences preoperative disability and patient-reported outcomes after reverse total shoulder arthroplasty. METHODS: Data were prospectively collected for patients who underwent reverse total shoulder arthroplasty for rotator cuff arthropathy or osteoarthritis with a rotator cuff tear at a single institution between 2009 and 2015...
September 11, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28891593/effect-of-radiosynoviorthesis-on-the-progression-of-arthropathy-and-haemarthrosis-reduction-in-haemophilic-patients
#6
M Querol-Giner, S Pérez-Alenda, M Aguilar-Rodríguez, J J Carrasco, S Bonanad, F Querol
INTRODUCTION: Repeated haemarthrosis is widely accepted as the triggering cause of synovitis and haemophilic arthropathy. A first-line treatment of chronic synovitis is radiosynoviorthesis (RS). The aim of this study was to evaluate the RS effects on the progression of arthropathy and on a reduction in bleeding in patients with haemophilia. METHODS: An observational-retrospective study was performed. Bleeding episodes in the 12 months following and in the 12 months preceding RS was compared...
September 11, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28891453/management-of-hemophilic-arthropathy-of-the-ankle
#7
E Carlos Rodriguez-Merchan
BACKGROUND: Hemophilic arthropathy (HA) of the ankle is prevalent in people with hemophilia (PWH). It is frequently severe and incapacitating, due to recurrent bleeding into the ankle articulation during infancy. Around 50% of hemophilic patients suffer from ankle pain and radiological signs of HA. OBJECTIVE: To review current treatment of HA of the ankle in PWH. METHOD: A literature review of hemophilic ankle arthropathy in PWH was performed utilizing MEDLINE (PubMed) and the Cochrane Library...
September 7, 2017: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/28886220/anti-inflammatory-effects-of-polyphenols-in-arthritis
#8
REVIEW
Francesca Oliviero, Anna Scanu, Yessica Zamudio-Cuevas, Leonardo Punzi, Paolo Spinella
Polyphenols have been extensively investigated with regard to their anti-oxidant, anti-inflammatory, and immunomodulant properties in many inflammatory chronic conditions. The aim of this review is to summarize how these compounds can modulate the inflammatory pathways which characterize the most prevalent arthropathies including osteoarthritis, rheumatoid arthritis and crystal-induced arthritis. Among polyphenols, epigallocatechin gallate, carnosol, hydroxytyrosol, curcumin, resveratrol, kaempferol and genistein have been the most widely investigated in arthritis...
September 8, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28884797/sapho-syndrome-associated-with-hidradenitis-suppurativa-and-pyoderma-gangrenosum-successfully-treated-with-adalimumab-and-methotrexate-a-case-report-and-review-of-the-literature
#9
REVIEW
Dunja A Vekic, Jane Woods, Peter Lin, Geoffrey D Cains
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare inflammatory condition describing the combination of skin, bone, and joint manifestations that has a heterogeneous presentation. We report a case of severe SAPHO syndrome in association with hidradenitis suppurativa and pyoderma gangrenosum in a 27-year-old male. The patient had an initial migratory arthritis affecting the knees, ankles, metacarpophalangeal joints, proximal interphalangeal joints, wrists, shoulder, and lower back, which progressed to a persistent arthritis and swelling at the sternum, shoulders, wrists, hands, feet, and lower back...
September 7, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28880117/international-variation-in-shoulder-arthroplasty
#10
Anne Lübbeke, Jonathan L Rees, Christophe Barea, Christophe Combescure, Andrew J Carr, Alan J Silman
Background and purpose - The number of shoulder registries increases. We assessed international trends in use of shoulder arthroplasty, and described the current state of procedure selection and outcome presentation as documented in national and regional joint registries. Methods - Published reports from 9 population-based shoulder arthroplasty registries (country/region: Norway, Sweden, New Zealand, Denmark, California, Australia, Emilia-Romagna, Germany, and United Kingdom) were analyzed. Data were extracted on age, sex, disease indication, type of surgical procedure, surgical volume, and outcomes...
September 7, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28879639/nitisinone-induced-keratopathy-in-alkaptonuria-a-challenging-diagnosis-despite-clinical-suspicion
#11
Andrew White, Michel C Tchan
Alkaptonuria is a rare disorder of amino acid metabolism that causes premature large joint and spine arthropathy and cardiac valvular disease. It is characterised by elevated levels of homogentisic acid. Nitisinone (NTBC) is a benzoylcyclohexane-1,3-dione that reversibly inhibits the activity of the enzymatic step immediately prior to homogentisate dioxygenase, hence reducing the production of homogentisic acid. Thus it is thought that nitisinone might be a treatment for alkaptonuria. A side effect of NTBC therapy is elevation of plasma tyrosine levels in a manner analogous to tyrosinemia type 2, another related condition which causes a painful palmoplantar hyperkeratosis and eye pathology described as conjunctivitis and herpetic-like corneal ulceration...
September 7, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28878852/potential-adjunctive-role-of-radiosynovectomy-in-primary-synovial-osteochondromatosis-of-the-knee-a-case-report
#12
Shelvin Kumar Vadi, Devendra Kumar Chouhan, Arun Kumar Reddy Gorla, Jaya Shukla, Ashwani Sood, Bhagwant Rai Mittal
Primary synovial osteochondromatosis (PSOC) is a rare but clinically significant cause of morbidity especially in the male population. Surgery is the primary treatment of choice, but the recurrence rate is reported to be high. Moreover, the presence of widespread loose bodies makes it a cumbersome procedure. The complete removal of the disease is tough at times and results in early recurrence. Radiosynovectomy is an established technique for treating various joint arthropathies. The role of radiosynovectomy in case of PSOC has not yet been explored...
September 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28878548/arthroscopic-diagnosis-and-treatment-of-shoulder-ochronotic-arthropathy-a-case-report
#13
Prateek Kumar Gupta, Ashis Acharya, Dhananjay Sabat, Amit Mourya
Alkaptonuria is a rare inherited metabolic disorder, caused by the deficiency of homogentisate 1,2 dioxygenase enzyme. The three major features of alkaptonuria are the presence of homogentisic acid in urine, ochronosis (bluish-black pigmentation in connective tissue) and arthritis of the spine and large joints. We present a 48 years old female presented with pain, restriction of movements of right shoulder. Arthroscopy was suggestive of ochronotic arthropathy. The definitive diagnosis of ochronosis was subsequently confirmed by laboratory and pathologic evaluation...
August 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28875360/-recurrent-instability-and-instability-arthropathy
#14
REVIEW
L Lacheta, S Siebenlist, A B Imhoff, L Willinger
Capsulolabral reconstruction (Bankart repair) is recommended as the first line treatment in young and functionally demanding active patients with anteroinferior shoulder instability, due to the high tendency to recurrent dislocation. This has become established both for arthroscopic and open primary shoulder stabilization with good clinical outcome; nevertheless, recurrence of dislocation is reported in up to 25% of patients. Risk factors for failed surgery are patient (e.g. young age, male gender and contact sports) and surgery (e...
September 5, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28873289/monitoring-joint-health-in-haemophilia-factors-associated-with-deterioration
#15
I A R Kuijlaars, M A Timmer, P de Kleijn, M F Pisters, K Fischer
INTRODUCTION: Joint bleeds in patients with haemophilia may result in haemophilic arthropathy. Monitoring joint health is essential for identifying early signs of deterioration and allows timely adjustment of treatment. AIM: The aim was to describe changes in joint health over 5-10 years follow-up and identify factors associated with joint health deterioration in patients with haemophilia. METHODS: A post hoc analysis was performed from previous cohort studies in patients with moderate/severe haemophilia, ≥16 years...
September 5, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28872563/jejunal-atresia-periodic-fevers-and-psoriatic-arthropathy-in-baraitser-winter-malformation-syndrome
#16
Avi Saskin, Marc Tischkowitz
No abstract text is available yet for this article.
October 2017: Clinical Dysmorphology
https://www.readbyqxmd.com/read/28861200/reverse-shoulder-arthroplasty-in-patients-with-rheumatoid-arthritis-a-systematic-review
#17
Chul-Hyun Cho, Du-Han Kim, Kwang-Soon Song
BACKGROUND: There are limited data available regarding the results of reverse shoulder arthroplasty (RSA) in patients with rheumatoid arthritis (RA). We performed a systematic review of the literature to investigate the radiological and clinical outcomes after RSA in patients with RA. METHODS: A literature search for publications between 1987 and 2014 was conducted by 2 independent reviewers using PubMed, Scopus, Embase, and Cochrane Central Register of Controlled Trials...
September 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28860213/-18-f-sodium-fluoride-pet-mr-based-localization-and-quantification-of-bone-turnover-as-a-biomarker-for-facet-joint-induced-disability
#18
N W Jenkins, J F Talbott, V Shah, P Pandit, Y Seo, W P Dillon, S Majumdar
Our aim was to prospectively evaluate the relationship between low back pain-related disability and quantitative measures from [(18)F]-sodium fluoride ([(18)F]-NaF) MR imaging. Six patients with facetogenic low back pain underwent dynamic [(18)F]-NaF PET/MR imaging. PET metrics were correlated with clinical measures and MR imaging grading of lumbar facet arthropathy. A significant positive correlation was observed between maximum facet joint uptake rate and clinical disability (P < .05). These data suggest that dynamic [(18)F]-NaF PET may serve as a useful biomarker for facetogenic disability...
August 31, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28840671/-treatment-for-charcot-arthropathy-five-year-follow-up
#19
I Caldiño-Lozada, D Rojas-Osorio, R Esperón-Hernández
INTRODUCTION: Charcot arthropathy is a deformity which alters foot biomechanics and generate bichemical reactions that affect articular joints and bone. The natural history shown us a prevalence on 1% and is classified by Eichenholtz and Simmons modification in four stages; Sanders describe its location in 5 specific areas. MATERIAL AND METHODS: Our goal was to evaluate the specific method of treatment depending in the different stages of the deformity according to the literature review and to our proposed algoritm...
March 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28836341/effect-of-late-prophylaxis-in-hemophilia-on-joint-status-a-randomized-trial
#20
Marilyn J Manco-Johnson, Bjorn Lundin, Sharon Funk, Charles Peterfy, David Raunig, Michael Werk, Christine L Kempton, Mark T Reding, Stefcho Goranov, Liana Gercheva, Luminita Rusen, Valentina Uscatescu, Marta Pierdominici, Sylvia Engelen, Jennifer Pocoski, Dale Walker, Walter Hong
BACKGROUND: Limited data exist on the impact of prophylaxis on adults with severe hemophilia A and pre-existing joint disease. OBJECTIVES: This analysis describes 3-year bleeding, joint, health-related quality-of-life (HRQoL), and other outcomes from the open-label, randomized, multinational SPINART study. PATIENTS/METHODS: Males aged 12-50 years with severe hemophilia A, ≥150 FVIII exposure days, no inhibitors, and no prophylaxis for >12 consecutive months in the past 5 years were randomized to sucrose-formulated recombinant FVIII (rFVIII-FS) prophylaxis or on-demand therapy (OD)...
August 24, 2017: Journal of Thrombosis and Haemostasis: JTH
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