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Tracheal papillomatosis

Satish Kalanjeri, Steve Hoffman, Carol Farver, Francisco Aécio Almeida
No abstract text is available yet for this article.
September 27, 2016: American Journal of Respiratory and Critical Care Medicine
Stalin Vinayagam, Mvs Satya Prakash, Pankaj Kundra, Surianarayana Gopalakrishnan
Endotracheal intubation was successfully accomplished with 70° rigid nasendoscope under video guidance in two patients in whom repeated attempts to secure airway with flexible fibreoptic bronchoscope were unsuccessful. Both patients had compromised airway (laryngeal papillomatosis and a huge thyroid swelling) and were uncooperative. Frova intubating introducer was used along with 70° rigid nasendoscope to accomplish tracheal intubation under video guidance.
July 2016: Indian Journal of Anaesthesia
E S Korovkina, O O Magarshak
A thorough collection of complaints and history data, physical examination, and lung function tests are necessary to confirm the diagnosis of asthma. The latter must be differentiated from different diseases in the majority of patients according to age. Recurrent respiratory papillomatosis is caused by human papillomavirus and involves mainly the upper respiratory tract. The paper describes a case of tracheal papillomatosis concurrent with atopic asthma.
2016: Terapevticheskiĭ Arkhiv
Selmin Karatayli-Ozgursoy, Justin Avery Bishop, Alexander Hillel, Lee Akst, Simon R A Best
AIM: Recurrent respiratory papillomatosis (RRP) is classically described as a benign neoplasm of the larynx caused by the low-risk human papillomavirus (HPV) viral subtypes. Nevertheless, transformation to dysplasia and invasive carcinoma can occur. We aimed to assess the prevalence of dysplasia and carcinoma-ex-papilloma in both adult-onset and juvenile-onset RRP and identify patient risk factors for this dysplastic transformation. MATERIAL AND METHODS: Ten-year retrospective chart review of a tertiary otolaryngology referral center...
March 2016: Annals of Otology, Rhinology, and Laryngology
Chuqin Zhang, Bobei Chen, Benyu Nan, Yingying Chen, Jinjian Gao, Saiyu Huang, Haijie Xiang, Xiao Yu, Xuejun Liu, Baozhen Luo
OBJECTIVE: This study was designed to explore the risk factors associated with severity of juvenile onset recurrent respiratory papillomatosis. METHOD: A retrospective study was conducted to study determinants of severe forms of juvenile recurrent onset respiratory papillomatosis. The patients were separated into different groups based on the onset age, the first recurrence of age, the first recurrence of period, gender and incision of tracheal respectively. The relationship among the lesion severity score,the involvement of the subregion, operation period and the next operation period were also explored...
December 2014: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Fatma Yıldırım, Murat Türk, Sedat Demircan, Nalan Akyürek, Ahmet Selim Yurdakul
Tracheal papilloma (TP) is characterized by papillomatous growth of the bronchial epithelium that involves the trachea as a response to Human Papilloma Virus (HPV) infection. A 40-year-old male, with 3-month history of progressive dyspnea was admitted to our hospital, and there were no any other respiratory symptoms. Physical examination was unremarkable. Chest computed tomography (CT) showed that there was a papillomatous mass at the distal trachea. The lesion occupied 80% of tracheal lumen. This patient received cryotherapy and mechanical debridement under general anesthesia and postoperative pathology showed endotracheal papillomatosis...
2015: Case Reports in Pulmonology
Yang Xiao, Jun Wang, Demin Han, Lijing Ma
OBJECTIVES: To describe an individual with recurrent respiratory papillomatosis that extended into the lung parenchyma and underwent malignant transformation and to discuss the characteristic imaging findings associated with this condition. METHODS: The clinical presentation of an individual with this unusual malignant transformation was reviewed. A literature search was performed to characterize the epidemiology, imaging findings and management of this condition...
July 2015: American Journal of the Medical Sciences
Julie Ahn, Justin A Bishop, Belinda Akpeng, Sara I Pai, Simon R A Best
OBJECTIVE: Identifying effective treatment for papillomatosis is limited by a lack of animal models, and there is currently no preclinical model for testing potential therapeutic agents. We hypothesized that xenografting of papilloma may facilitate in vivo drug testing to identify novel treatment options. METHODS: A biopsy of fresh tracheal papilloma was xenografted into a NOD-scid-IL2Rgamma(null) (NSG) mouse. RESULTS: The xenograft began growing after 5 weeks and was serially passaged over multiple generations...
February 2015: Annals of Otology, Rhinology, and Laryngology
Lamia Jamjoom, Emmanuel C Obusez, Jacobo Kirsch, Thomas Gildea, Tan-Lucien Mohammed
This pictorial essay illustrates, describes, and correlates computed tomographic findings of tracheal neoplasms with fiberoptic bronchoscopy findings. Corresponding computed tomography (CT) and bronchoscopy findings of common primary tracheal neoplasms; squamous cell papilloma, papillomatosis, squamous cell carcinoma, adenoid cystic adenoma, non-Hodgkin׳s lymphoma, and a secondary malignant neoplasm of the trachea; and renal cell carcinoma were correlated.
September 2014: Current Problems in Diagnostic Radiology
Emmanuel C Obusez, Lamia Jamjoom, Jacobo Kirsch, Thomas Gildea, Tan-Lucien Mohammed
To illustrate and describe computed tomographic large airway pathology and correlate with fiberoptic bronchoscopy findings. Commonly encountered diseases of the large airway include tracheobronchial amyloidosis, tracheobronchopathia osteochondroplastica, tracheobronchomegaly, laryngotracheobronchial papillomatosis, relapsing polychondritis, Wegener granulomatosis, sarcoidosis, and tracheal stenosis. Computed tomography manifestations and bronchoscopic findings of these selected large airway diseases are discussed...
September 2014: Current Problems in Diagnostic Radiology
M Grasso, M Remacle, V Bachy, S Van Der Vorst, G Lawson
Recurrent respiratory papillomatosis is a viral-induced disease, associated with exophytic epithelial lesions affecting the upper airways. Problem of treatment is the high recurrence of papilloma growth after surgical removal; therefore, adjuvant therapy schemes have been established. We used cidofovir, 7.5 mg/ml, in adjuvant therapy in the past years. Out of 31 adult patients treated with the drug, 26 (83.9 %) are at the moment in complete response. 19 (73 % of pts with CR) of those 26 patients were cured with a number of injections between 1 and 4 (mean 2...
November 2014: European Archives of Oto-rhino-laryngology
Jagdish Chaturvedi, V Sreenivas, V Hemanth, R Nandakumar
To demonstrate the role of oral acyclovir in monthly regimes after microdebrider assisted excision in 3 patients with adult recurrent respiratory papillomatosis (ARRP). Three patients with ARRP who presented to a tertiary referral hospital in stridor were initially treated with a tracheostomy in order to secure airway. On further evaluation by videolaryngoscopy extensive bilateral laryngeal papillomatosis was noted with history of similar conditions in the past for which they were repeatedly operated. They were admitted and underwent Microlaryngeal surgery and laryngeal microdebrider assisted surgery under general anesthesia...
January 2014: Indian Journal of Otolaryngology and Head and Neck Surgery
Abdul Hamid Alraiyes, Michael S Machuzak, Thomas R Gildea
Respiratory tract infection with human papillomavirus has been associated with major airway complications, including tracheal stenosis. We report a case of recurrent respiratory papillomatosis infection complicated with iatrogenic airway fire injury causing airway stenosis. This was treated with reconstruction and a silicone Y stent placement. Three years after the stent placement, the patient presented with wheezing and shortness of breath. Bronchoscopy revealed tracheal narrowing proximal to the tracheal limb of the Y stent...
October 2013: Journal of Bronchology & Interventional Pulmonology
Zhonglin Hao, Thomas Dillard, Paul Biddinger, Vijay Patel
A 52-year-old non-smoker and renal transplant recipient developed an incessant cough. A CT scan of the thorax revealed ill-defined hazy opacities in the right upper lung. He was diagnosed with non-tuberculosis Mycobacterium chelonae/abscessus infection based on sputum culture results. A trial of antibiotics initially resulted in some clinical improvement. A subsequent CT of the thorax documented worsening of the lesions in the right lung and new lesions on the left. An intratracheal growth was noted. Bronchoscopy with biopsy of the tracheal lesions documented respiratory papillomatosis with transformation to squamous cell cancer...
2013: BMJ Case Reports
Phayvanh P Sjogren, James D Sidman
IMPORTANCE: Obstructing tracheobronchial diseases in children can be treated by a variety of techniques. The nonfiberoptic delivery of the carbon dioxide laser coupled to a rigid bronchoscope has rarely been described for this purpose and has unique advantages over other treatment methods. OBJECTIVES: To report the indications, safety, efficacy, and limitations of the carbon dioxide laser delivered through a rigid bronchoscope for tracheobronchial lesions in the pediatric population...
March 2013: JAMA Otolaryngology—Head & Neck Surgery
Yan Gao, Zujiu Cao
A 63-year-old male patient, with 5 years history of progressive dyspnea and aggravation for 1 year, was hospitalized in our hospital; and there was a slight cough, but no cough phlegm, chest pain, hemoptysis or hoarseness. Physical examination showed that there was a third-degree respiratory distress, obvious three depression sign, but no mass in the neck. Electronic laryngoscopy examination reported a mulberry-like mass in trachea about 1.5cm from the glottis. The tumor occupied 90% range of lumen with its base close to the anterior wall of trachea,and tumor could move up and down with cough airflow...
January 2013: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
R E A Tjon Pian Gi, T Ilmarinen, E R van den Heuvel, L M Aaltonen, J Andersen, J W Brunings, M Chirila, A Dietz, F Ferran Vilà, G Friedrich, H H W de Gier, W Golusinski, M Graupp, A Hantzakos, R Horcasitas, J Jackowska, J C Koelmel, G Lawson, F Lindner, M Remacle, C Sittel, V Weichbold, M Wierzbicka, F G Dikkers
Intralesional use of cidofovir (Vistide(®)) has been one of the mainstays of adjuvant therapy in patients with recurrent respiratory papillomatosis (RRP) since 1998. In 2011, a communication provided by the producer of cidofovir addressed very serious side effects concerning its off-label use. As this was a general warning, it was inconclusive whether this would account for its use in RRP. The aim of this study is to determine whether nephrotoxic, neutropenic, or oncogenic side effects have occurred after intralesional use of cidofovir in patients with RRP...
May 2013: European Archives of Oto-rhino-laryngology
Ya-li Guo, Tie-song Zhang
OBJECTIVE: To explore the long-term therapeutic effects of tracheotomy on juvenile onset recurrent respiratory papillomatosis in children. METHODS: Between 1993 and 2007, 86 cases of juvenile onset recurrent respiratory papillomatosis (JRRP) in children were encounted and divided into tracheotomy group and conventional surgery group, the clinical data of these children were retrospectively analyzed. RESULTS: There were 29 cases in tracheotomy group, the time of carrying tracheal casing pipe was 13 - 66...
December 2012: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Yukihiro Hasegawa, Nobuyuki Sato, Hiromichi Niikawa, Satoshi Kamata, Seiya Sannohe, Hidekachi Kurotaki, Taisuke Sasaki, Akio Ebina
A 75-year-old male was admitted to our hospital in December 2011 with a mass in the right upper pulmonary lobe. He was incidentally diagnosed as having tracheal papillomas 10 years ago. Bronchoscopy revealed multiple polypoid papillomas in the dorsal lesion of the trachea. Polymerase chain reaction amplification detected human papillomavirus type 11 DNA in the papilloma tissues. A computed tomography scan demonstrated the occlusion of the right superior segment bronchus with distal consolidation. Furthermore, F-18 fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography showed intense tracer uptake in the right superior segment of the lung...
January 2013: Japanese Journal of Clinical Oncology
Jun Wang, De-Min Han, Li-Jing Ma, Jing-Ying Ye, Yang Xiao, Qing-Wen Yang
BACKGROUND: Juvenile onset recurrent respiratory papillomatosis (JORRP) is a relatively rare disease. It affects the larynx in most cases. Because reports on JORRP to the lower respiratory tract (LRT) are few, we investigated clinical features of patients with a history of JORRP to analyze the risk factors of this disease. METHODS: Data from 208 JORRP patients admitted to Beijing Tongren Hospital from January 2008 to December 2010 were reviewed. Gender, age at onset of symptoms, age at first surgery, duration of symptoms before the first surgical procedure, the number of surgical procedures, mean interval between surgical interventions, and the number of tracheotomies in patients with and without LRT spread of JORRP were analyzed...
October 2012: Chinese Medical Journal
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