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https://www.readbyqxmd.com/read/28922374/fractional-laser-exposure-induces-neutrophil-infiltration-n1-phenotype-into-the-tumor-and-stimulates-systemic-anti-tumor-immune-response
#1
Masayoshi Kawakubo, Shadmehr Demehri, Dieter Manstein
BACKGROUND: Ablative fractional photothermolysis (aFP) using a CO2 laser generates multiple small diameter tissue lesions within the irradiation field. aFP is commonly used for a wide variety of dermatological indications, including treatment of photodamaged skin and dyschromia, drug delivery and modification of scars due to acne, surgical procedures and burns. In this study we explore the utility of aFP for treating oncological indications, including induction of local tumor regression and inducing anti-tumor immunity, which is in marked contrast to current indications of aFP...
2017: PloS One
https://www.readbyqxmd.com/read/28920474/the-state-of-ethnic-dermatology-in-canada
#2
Boluwaji Ogunyemi, Yvette Miller-Monthrope
Approximately 30% of Canadians will be members of a visible minority by 2031. When dermatology became an independent medical discipline in the late 18th and early 19th centuries, most residents of Canada and the United States were of Northern European descent. Morphology and descriptions of dermatoses are based on patients with light skin. Skin of colour dermatology refers to a unique field in dermatology dedicated to the diagnosis and management of disorders that are more prevalent in patients with moderately to richly pigmented skin...
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28919686/high-performance-liquid-chromatography-ultraviolet-photodiode-array-detection-method-for-aflatoxin-b1-in-cattle-feed-supplements
#3
Lazuardi Mochamad, Bambang Hermanto
AIM: The objective of the current study is to determine the concentration of aflatoxin B1 using high-performance liquid chromatography (HPLC) with a photodiode array (PDA) detector. MATERIALS AND METHODS: Aflatoxin B1 certified reference grade from Trilogy Analytical Laboratory dissolved acetonitrile (ACN) at 10 µg/mL was using standard assessment. HPLC instruments such as ultraviolet-PDA detector used a Shimadzu LC-6AD pump with DGU-20A5 degasser, communication module-20A, and PDA detector SPD-M20A with FRC-10A fraction collector...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28917458/adherence-to-over-the-counter-benzoyl-peroxide-in-patients-with-acne
#4
Annie H Huyler, Andrea L Zaenglein
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28916394/a-useful-strategy-based-on-chromatographic-data-combined-with-quality-by-design-approach-for-food-analysis-applications-the-case-study-of-furanic-derivatives-in-sugarcane-honey
#5
Pedro Silva, Catarina L Silva, Rosa Perestrelo, Fernando M Nunes, José S Câmara
Sugarcane honey (SCH) is one of the Madeira Island products par excellence and it is now popular worldwide. Its sui generis and peculiar sensory properties, explained by a variety of volatile compounds including furanic derivatives (FDs), arise mainly from manufacturing and storage conditions. A simple high-throughput approach based on semi-automatic microextraction by packed sorbent (MEPS) combined with ultra-high performance liquid chromatography (UHPLC) was developed and validated for identification and quantification of target FDs in sugarcane honey...
September 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28916096/the-preparation-of-a-poly-pentaerythritol-tetraglycidyl-ether-co-poly-ethylene-imine-organic-monolithic-capillary-column-and-its-application-in-hydrophilic-interaction-chromatography-for-polar-molecules
#6
Ye Chen, Yan Shu, Zihui Yang, Xumei Lv, Wangming Tan, Yingzhuang Chen, Ming Ma, Bo Chen
An easy single-step thermal treatment "one-pot" approach for the preparation of poly (pentaerythritol tetraglycidyl ether-co-poly ethylene imine) organic monolithic capillary columns was developed successfully. The column was prepared by the epoxy-amine ring-opening polymerization of pentaerythritol tetraglycidyl ether (PTE) with poly (ethylene imine) (PEI) using acetonitrile (ACN) and polyethylene glycol 600 (PEG 600) as the porogenic system at 60 °C for 12 h. The obtained monolith was homogeneous and permeable...
October 2, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28915843/protective-effects-of-gaba-against-metabolic-and-reproductive-disturbances-in-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#7
Asad Ullah, Sarwat Jahan, Suhail Razak, Madeeha Pirzada, Hizb Ullah, Ali Almajwal, Naveed Rauf, Tayyaba Afsar
BACKGROUND: PCOs is a heterogeneous disorder with anovulation/oligo ovulation usually taken as oligo menorrhoea or amenorrhoea, hyperandrogenemia, hirsutism, acne, androgen alopecia and polycystic ovaries as the key diagnostic feathers. The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance. METHODS: PCOs in Adult female rat was induced by the daily gastric administration of letrozole (1 mg/kg/day) in CMC (0...
September 15, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28913735/efficacy-and-safety-of-tazarotene-0-1-plus-clindamycin-1-gel-versus-adapalene-0-1-plus-clindamycin-1-gel-in-facial-acne-vulgaris-a-randomized-controlled-clinical-trial
#8
Rituparna Maiti, Chandra Sekhar Sirka, M A Ashique Rahman, Anand Srinivasan, Sansita Parida, Debasish Hota
BACKGROUND: Acne vulgaris is a multifactorial disorder which is ideally treated with combination therapy with topical retinoids and antibiotics. OBJECTIVES: The present study was conducted to compare the efficacy and safety of tazarotene plus clindamycin against adapalene plus clindamycin in facial acne vulgaris. METHODS: This study is a randomized, open-label, parallel design clinical trial conducted on 60 patients with facial acne at the outpatient dermatology department in a tertiary healthcare center...
September 14, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28912911/doxycycline-induced-acute-pancreatitis-a-rare-adverse-event
#9
Prashanth Rawla, Jeffrey Pradeep Raj
Doxycycline is a broad-spectrum antibiotic belonging to the tetracycline group which acts by inhibiting bacterial protein synthesis. It is considered to be a relatively safe drug. We report a case of doxycycline-induced acute pancreatitis (DIAP) in an adult female patient who was started on the usual therapeutic dose 1 week before for acne vulgaris. The WHO causality assessment was possible, and the Naranjo scale confirmed it as "definite" adverse drug reaction. A brief literature review on case reports previously reporting DIAP has also been summarized...
August 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28912620/hormonal-contraception-and-the-development-of-autoimmunity-a-review-of-the-literature
#10
William V Williams
Estrogens and progestins are known to have profound effects on the immune system and may modulate the susceptibility to autoimmune diseases. A comprehensive literature search was carried out using PubMed for any of 153 autoimmune disease terms and the terms contraception, contraceptive, or their chemical components with limits of Humans + Title or Abstract. Over 1,800 titles were returned and scanned, 352 papers retrieved and reviewed in depth and an additional 70 papers retrieved from the bibliographies. Based on this review, substantial evidence exists linking the use of combined oral contraceptives to a lower incidence of hyperthyroidism, an increase in multiple sclerosis, ulcerative colitis, Crohn's disease, Systemic Lupus Erythematosus, and interstitial cystitis...
August 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28911660/an-ecofriendly-green-liquid-chromatographic-method-for-simultaneous-determination-of-nicotinamide-and-clindamycin-phosphate-in-pharmaceutical-gel-for-acne-treatment
#11
Fawzia Ibrahim, Asmaa Kamal El-Deen, Samah Abo El Abass, Kuniyoshi Shimizu
A new green micellar liquid chromatographic method was developed and validated for the quantitative estimation of nicotinamide (NICO) and clindamycin phosphate (CLD) in bulk and pharmaceutical gel formulation. The analytes are well resolved in less than 6.0 minutes using micellar mobile phase consisting of 0.10M sodium dodecyl sulfate (SDS), 0.3% triethylamine, and 10% 2-propanol in 0.02M orthophosphoric acid at pH 3.0, running through an Eclipse XDB-C8 column (150 mm×4.6 mm, 5 μm particle size) with flow rate 1...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911609/antibacterial-and-laxative-activities-of-strictinin-isolated-from-pu-er-tea-camellia-sinensis
#12
Sheng-Kuo Hsieh, Jun-Rui Xu, Nan-Hei Lin, Yue-Chiun Li, Guan-Heng Chen, Ping-Chung Kuo, Wen-Ying Chen, Jason T C Tzen
Strictinin, the major phenolic compound in Pu'er teas produced from young leaves and buds of wild trees, was isolated to evaluate its antibacterial and laxative activities. The minimum inhibitory concentrations of strictinin against Propionibacterium acnes and Staphylococcus epidermidis were determined as 250 μM and 2000 μM, respectively, apparently higher than those of several antibiotics commonly used for bacterial infections. The additive and synergistic effects on the inhibitory activities of strictinin combined with other commercial antibiotics were observed in two bacteria tested in this study via the analysis of fractional inhibitory concentrations...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28910098/fast-and-simple-protocols-for-mass-spectrometry-based-proteomics-of-small-fresh-frozen-uterine-tissue-sections
#13
Irena Dapic, Naomi Uwugiaren, Petra J Jansen, Garry L Corthals
Human tissues are an important link between organ specific spatial molecular information, patient pathology and patient treatment options. However, patient tissues are uniquely obtained by time and location, and limited in their availability and size. Currently little knowledge exists about appropriate and simplified protocols for routine MS-based analysis of the various types and sizes of tissues. Following standard procedures used in pathology we selected small fresh frozen uterine tissue samples to investigate how the tissue preparation protocol affected the subsequent proteomics analysis...
September 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28903585/reconsidering-accuracy-of-acne-self-reports
#14
Cheng-Wei Liu, Andrea Reed, Mia Sisic, Jerry Tan
No abstract text is available yet for this article.
July 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28902026/chemical-peels-indications-and-special-considerations-for-the-male-patient
#15
Jeave Reserva, Amanda Champlain, Seaver L Soon, Rebecca Tung
BACKGROUND: Chemical peels are a mainstay of aesthetic medicine and an increasingly popular cosmetic procedure performed in men. OBJECTIVE: To review the indications for chemical peels with an emphasis on performing this procedure in male patients. MATERIALS AND METHODS: Review of the English PubMed/MEDLINE literature and specialty texts in cosmetic dermatology, oculoplastic, and facial aesthetic surgery regarding sex-specific use of chemical peels in men...
September 4, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28902005/propionibacterium-acnes
#16
Inês Marques Carneiro, Ana Sousa Pereira, Sara Pinto, Filipa Prata, Cláudia C Faria, José Gonçalo Marques
Infection after implantation of ventriculo-peritoneal (VP) shunts is associated with significant morbidity and mortality. We describe a 9-year-old girl with Propionibacterium acnes shunt infection with negative cerebrospinal fluid cultures, diagnosed by broad-range 16S-rRNA gene PCR. This case supports the use of this molecular diagnostic technique in shunt infections, where the offending pathogens are difficult to culture using traditional methods.
September 7, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28901892/the-effect-of-anthocyanin-supplementation-in-modulating-platelet-function-in-sedentary-population-a-randomised-double-blind-placebo-controlled-cross-over-trial
#17
Kiara Thompson, Holly Hosking, Wayne Pederick, Indu Singh, Abishek B Santhakumar
The anti-thrombotic properties of anthocyanin (ACN) supplementation was evaluated in this randomised, double-blind, placebo (PBO) controlled, cross-over design, dietary intervention trial in sedentary population. In all, sixteen participants (three males and thirteen females) consumed ACN (320 mg/d) or PBO capsules for 28 d followed by a 2-week wash-out period. Biomarkers of thrombogenesis and platelet activation induced by ADP; platelet aggregation induced by ADP, collagen and arachidonic acid; biochemical, lipid, inflammatory and coagulation profile were evaluated before and after supplementation...
September 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28898844/polar-aprotic-solvent-water-mixture-as-the-medium-for-catalytic-production-of-hydroxymethylfurfural-hmf-from-bread-waste
#18
Iris K M Yu, Daniel C W Tsang, Season S Chen, Lei Wang, Andrew J Hunt, James Sherwood, Karine De Oliveira Vigier, François Jérôme, Yong Sik Ok, Chi Sun Poon
Valorisation of bread waste for hydroxymethylfurfural (HMF) synthesis was examined in dimethyl sulfoxide (DMSO)-, tetrahydrofuran (THF)-, acetonitrile (ACN)-, and acetone-water (1:1v/v), under heating at 140°C with SnCl4 as the catalyst. The overall rate of the process was the fastest in ACN/H2O and acetone/H2O, followed by DMSO/H2O and THF/H2O due to the rate-limiting glucose isomerisation. However, the formation of levulinic acid (via rehydration) and humins (via polymerisation) was more significant in ACN/H2O and acetone/H2O...
September 1, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28898474/quality-of-life-measurement-in-acne-position-paper-of-the-european-academy-of-dermatology-and-venereology-eadv-task-forces-on-quality-of-life-and-patient-oriented-outcomes-qol-and-po-and-acne-rosacea-and-hidradenitis-suppurativa-arhs
#19
REVIEW
P V Chernyshov, C C Zouboulis, L Tomas-Aragones, G B Jemec, L Manolache, T Tzellos, F Sampogna, A W M Evers, C Dessinioti, S E Marron, V Bettoli, O D van Cranenburgh, A Svensson, A I Liakou, F Poot, J C Szepietowski, Salek, A Y Finlay
Acne causes profound negative psychological and social effects on the quality of life (QoL) of patients. The European Dermatology Forum S3-Guideline for the Treatment of Acne recommended adopting a QoL measure as an integral part of acne management. Because of constantly growing interest in health-related QoL assessment in acne and because of the high impact of acne on patients' lives, the European Academy of Dermatology and Venereology Task Force on QoL and Patient Oriented Outcomes and the Task Force on Acne, Rosacea and Hidradenitis Suppurativa have documented the QoL instruments that have been used in acne patients, with information on validation, purposes of their usage, description of common limitations and mistakes in their usage and overall recommendations...
September 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28898196/teens-and-technology-transforming-acne-treatment
#20
Donna Lee Ettel, Lora Rose Lamanno, Sarah Anne Neyra, Wallace John Ettel, George Leonard Ettel Iii, Matthew Kevin Mitchell
INTRODUCTION: Although the Internet contains many health Web sites with valid information, it also contains sites with false information. OBJECTIVE: To learn whether high school students searching health care information believe they are using evidence-based sites and to understand their topics of interest, frequently navigated sites, and trust/confidence in the credibility of information found. DESIGN: Cross-sectional. MAIN OUTCOME MEASURES: Students at a private high school answered an anonymous survey inquiring about their belief that they were using evidence-based sites, topics of interest, search engines of choice, and their trust in information obtained...
2017: Permanente Journal
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