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https://www.readbyqxmd.com/read/28930438/supported-planar-mammalian-membranes-as-models-of-in-vivo-cell-surface-architectures
#1
Han-Yuan Liu, Hannah Grant, Hung-Lun Hsu, Raya Sorkin, Filip Bošković, G J L Wuite, Susan Daniel
Emerging technologies use cell plasma membrane vesicles or 'blebs' as an intermediate to form molecularly complete, planar cell surface mimetics that are compatible with a variety of characterization tools and microscopy methods. This approach enables direct incorporation of membrane proteins into supported lipid bilayers without using detergents and reconstitution and preserves native lipids and membrane species. Such a system can be advantageous as in vitro models of in vivo cell surfaces for study of the roles of membrane proteins as drug targets in drug delivery, host-pathogen interactions, tissue engineering, and many other bioanalytical and sensing applications...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28924697/chiropractic-spinal-manipulation-and-the-risk-for-acute-lumbar-disc-herniation-a-belief-elicitation-study
#2
Cesar A Hincapié, J David Cassidy, Pierre Côté, Y Raja Rampersaud, Alejandro R Jadad, George A Tomlinson
PURPOSE: Chiropractic spinal manipulation treatment (SMT) is common for back pain and has been reported to increase the risk for lumbar disc herniation (LDH), but there is no high quality evidence about this. In the absence of good evidence, clinicians can have knowledge and beliefs about the risk. Our purpose was to determine clinicians' beliefs regarding the risk for acute LDH associated with chiropractic SMT. METHODS: Using a belief elicitation design, 47 clinicians (16 chiropractors, 15 family physicians and 16 spine surgeons) that treat patients with back pain from primary and tertiary care practices were interviewed...
September 18, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28924554/molecular-cloning-and-functional-identification-of-sterol-c24-methyltransferase-gene-from-tripterygium-wilfordii
#3
Hongyu Guan, Yujun Zhao, Ping Su, Yuru Tong, Yujia Liu, Tianyuan Hu, Yifeng Zhang, Xianan Zhang, Jia Li, Xiaoyi Wu, Luqi Huang, Wei Gao
Sterol C24-methyltransferase (SMT) plays multiple important roles in plant growth and development. SMT1, which belongs to the family of transferases and transforms cycloartenol into 24-methylene cycloartenol, is involved in the biosynthesis of 24-methyl sterols. Here, we report the cloning and characterization of a cDNA encoding a sterol C24-methyltransferase from Tripterygium wilfordii (TwSMT1). TwSMT1 (GenBank access number KU885950) is a 1530 bp cDNA with a 1041 bp open reading frame predicted to encode a 346-amino acid, 38...
September 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28905117/mechanical-characteristics-of-the-maxillary-sinus-schneiderian-membrane-ex-vivo
#4
Angel Insua, Florencio Monje-Gil, Lucía García-Caballero, Jordi Caballé-Serrano, Hom-Lay Wang, Alberto Monje
OBJECTIVES: It has been speculated that certain Schneiderian membrane thickness (SMT) might be more prone to perforation. This investigation was aimed at studying the mechanical characteristics of the Schneiderian membrane under one- and two-dimensional tests and their correlation to the histological SMT in human samples. MATERIAL AND METHODS: Sixteen Schneiderian membranes were collected from 11 cadaver heads treated with Thiel's embalming method. The samples were processed and analyzed clinically and histologically...
September 13, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28891098/heterometallic-zn3ln3-ensembles-containing-%C3%AE-6-co3-ligand-and-triangular-disposition-of-ln3-ions-single-molecule-toroic-smt-and-single-molecule-magnet-smm-behavior
#5
Vadapalli Chandrasekhar, Enrique Colacio, J M Herrera, W Wernsdorfer, Y Lan, E Suturina, I Kuprov, J Goura
Two new heterometallic Zn3Dy3 (Ln3+=Dy, Tb) complexes with a double triangular topology of the metal ions have been assembled from the polytopicMannich base ligand 6,6'-{(2-(dimethylamino) ethyl azanediyl)bis(methylene)}bis(2-methoxy-4-methylphenol) (H2L)with the aidof in situ generated carbonate ligand from atmospheric CO2 fixation. Theoretical calculations indicate axial ground states for the Ln3+ ions in these complexes with their local magnetic moments being almost coplanarand tangential to the Ln3+ atoms defining the equilateral triangle...
September 11, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28888121/occurrence-distribution-ecological-and-resistance-risks-of-antibiotics-in-surface-water-of-finfish-and-shellfish-aquaculture-in-bangladesh
#6
Anwar Hossain, Shihori Nakamichi, Md Habibullah-Al-Mamun, Keiichiro Tani, Shigeki Masunaga, Hiroyuki Matsuda
The present study for the first time reports the occurrence, distribution, ecological and resistance risks of antibiotics in the surface water of freshwater finfish and brackish water shellfish aquaculture in Bangladesh. Among the nine targets, seven antibiotics were detected in finfish aquaculture, whereas four in shellfish aquaculture. The concentrations (ranges) and overall detection frequency of sulfamethoxazole (SMX) (nd-20.02 ng L(-1) and 73%), trimethoprim (TMP) (nd-41.67 ng L(-1) and 60%), tylosin (TYL) (nd-39...
August 30, 2017: Chemosphere
https://www.readbyqxmd.com/read/28863989/sorption-of-sulfamethazine-to-biochars-as-affected-by-dissolved-organic-matters-of-different-origin
#7
Mingyun Jia, Fang Wang, Yongrong Bian, Robert D Stedtfeld, Guangxia Liu, Jinping Yu, Xin Jiang
Sorption characteristic of sulfamethazine (SMT) to straw biochars pyrolyzed at 300°C (BC300) and 600°C (BC600), and the effect of ubiquitous DOM were investigated. Results showed that physisorption (partition) and weak chemical binding (π-π EDA interaction) dominated the sorption of SMT to BC300 and BC600, respectively. Graphene sheets in biochar played important roles in the sorption of SMT, leading to higher sorption capacity (Kf) on BC600 (1.77mg(1-n)L(n)g(-1)) than BC300 (0.11mg(1-n)L(n)g(-1)). Sorption amount of SMT to BC300 was not affected by polysaccharide and malic acid, while it was slightly promoted by citric acid, but dramatically increased 1...
August 29, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28856699/gender-differences-in-disordered-eating-behaviors-and-body-dissatisfaction-among-adolescents-with-type-1-diabetes-results-from-diabetes-miles-youth-australia
#8
E Araia, Christel Hendrieckx, Timothy Skinner, Frans Pouwer, Jane Speight, Ross M King
OBJECTIVE: To examine gender differences in disordered eating behaviors (DEB) and body dissatisfaction in adolescents with type 1 diabetes. While evidence shows that female youth with type 1 diabetes are more prone to DEB compared to their peers without diabetes, little is known about male adolescents. METHOD: In a national online survey, adolescents (13-19 years) with type 1 diabetes for ≥1 year completed the Diabetes Eating Problem Survey-Revised (DEPS-R), and the Body Mass Index Silhouette Matching Test (BMI-SMT) and items on binge eating and insulin omission...
August 30, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28822473/influence-of-spinal-manipulative-therapy-force-magnitude-and-application-site-on-spinal-tissue-loading-a-biomechanical-robotic-serial-dissection-study-in-porcine-motion-segments
#9
Martha Funabashi, François Nougarou, Martin Descarreaux, Narasimha Prasad, Greg Kawchuk
OBJECTIVE: In order to define the relation between spinal manipulative therapy (SMT) input parameters and the distribution of load within spinal tissues, the aim of this study was to determine the influence of force magnitude and application site when SMT is applied to cadaveric spines. METHODS: In 10 porcine cadavers, a servo-controlled linear actuator motor provided a standardized SMT simulation using 3 different force magnitudes (100N, 300N, and 500N) to 2 different cutaneous locations: L3/L4 facet joint (FJ), and L4 transverse processes (TVP)...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28816381/non-exposed-endoscopic-wall-inversion-surgery-for-submucosal-tumor-of-the-duodenum-a-novel-case-report
#10
Prasit Mahawongkajit, Ajjana Techagumpuch, Pakkavuth Chanswangphuvana
Laparoscopic and endoscopic cooperative surgery for duodenal tumor is the precise oncologic resection procedure and the closure of the defect (1). Non-exposed Endoscopic Wall-inversion Surgery (NEWS) is a novel minimally invasive technique for gastric submucosal mass (SMT) and early gastric cancer having advantageous precision to determine the resection line with no risk of peritoneal contamination (2-5). We describe the NEWS technique that we applied and performed for a small duodenal SMT. This article is protected by copyright...
August 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28816375/adenocarcinoma-of-the-colon-presenting-as-a-submucosal-tumor
#11
Hourin Cho, Shigeki Sekine, Masau Sekiguchi
A 64-year-old woman underwent colonoscopy for abdominal discomfort and a protruded lesion measuring approximately 10 mm was detected in the descending colon. The tumor was entirely covered by normal-appearing mucosa and was regarded as a submucosal tumor (SMT). A small adenomatous polyp was present beside the SMT (Figure 1). For precise histological assessment of the SMT and therapeutic purpose of the coexisted polyp, we performed complete resection of the lesions by endoscopic submucosal dissection. This article is protected by copyright...
August 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28802133/sorptive-removal-of-ionizable-antibiotic-sulfamethazine-from-aqueous-solution-by-graphene-oxide-coated-biochar-nanocomposites-influencing-factors-and-mechanism
#12
Danlian Huang, Xi Wang, Chen Zhang, Guangming Zeng, Zhiwei Peng, Jin Zhou, Min Cheng, Rongzhong Wang, Zhengxun Hu, Xiang Qin
Significant concerns have been raised over antibiotics pollution in aquatic environments in recent years. In this study, sorption of sulfamethazine (SMT) by novel graphene oxide-coated biochar nanocomposites (GO-BC) based on graphene oxide (GO) with bamboo sawdust biochar (BC) was investigated. In comparison with the original BC, the sorption capacity of GO-BC for SMT increased by 1.14 times. Sorption of SMT onto GO-BC was proved to be dominantly by chemisorption, and Freundlich isotherm described the sorption adequately...
November 2017: Chemosphere
https://www.readbyqxmd.com/read/28801071/comparison-of-2-lumbar-manual-therapies-on-temporal-summation-of-pain-in-healthy-volunteers
#13
Charles W Penza, Maggie E Horn, Steven Z George, Mark D Bishop
The purpose of this study was to compare the immediate change in temporal summation of heat pain (TSP) between spinal manipulation (SMT) and spinal mobilization (MOB) in healthy volunteers. Ninety-two volunteers (24 male; 23.8 ± 5.3 years) were randomized to receive SMT, MOB, or no treatment (REST) for 1 session. Primary outcomes were changes in TSP, measured at the hand and foot, immediately after the session. A planned subgroup analysis investigated effects across empirically derived TSP clusters. For the primary outcome there were no differences in the immediate change in TSP measured at the foot between SMT and MOB, however, both treatments were superior to the REST condition...
August 9, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28771400/single-incision-laparoscopic-intragastric-surgery-for-gastric-submucosal-tumor-located-adjacent-to-esophagogastric-junction-report-of-four-cases
#14
Shinsuke Katsuyama, Kiyokazu Nakajima, Yukinori Kurokawa, Tsuyoshi Takahashi, Yasuhiro Miyazaki, Tomoki Makino, Makoto Yamasaki, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
BACKGROUND: Laparoscopic local gastric resection has become the standard form of surgery for gastric submucosal tumors (SMTs) and is currently being actively selected for these cases. However, total gastrectomy or proximal gastrectomy is performed when tumors are adjacent to the cardia of stomach. Unfortunately, these procedures are highly invasive and can cause marked decreases in activities of daily living. We perform a single-incision laparoscopic intragastric surgery (sLIGS), which are both minimally invasive and offers improved cosmetic outcomes, to treat SMT located adjacent to the esophagogastric junction (EGJ)...
August 3, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28767573/endoscopic-resection-for-small-esophageal-submucosa-tumor-band-ligation-versus-conventional-endoscopic-mucosal-resection
#15
COMPARATIVE STUDY
Cheol Woong Choi, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park, Su Jin Kim
Because an esophageal submucosa tumor (SMT) may be malignant despite its small size, a safe endoscopic resection method is needed in some small SMTs. Conventional endoscopic mucosal resection (EMR) may be simple, but incomplete pathologic resection margin status is common. We aimed to investigate the clinical outcomes of 2 kinds of EMR techniques (conventional EMR and EMR with band ligation device) and to evaluate the factors associated with incomplete pathologic resection.We evaluated the medical records of 36 patients...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28757113/cardiovascular-risk-and-the-effect-of-nitric-oxide-synthase-inhibition-in-female-rats-the-role-of-estrogen
#16
Jaqueline C Castardo-de-Paula, Blenda H de Campos, Eric D T Amorim, Rosiane V da Silva, Carine C de Farias, Luciana Higachi, Phileno Pinge-Filho, Décio S Barbosa, Marli C Martins-Pinge
It is known that autonomic modulation is responsive to ovarian hormone levels and that estrogen increases nitric oxide (NO) bioavailability. However, little is known about the interaction of nitric oxide synthase (NOS) isoforms with autonomic modulation, oxidative stress and cardiovascular risk in females. This study aimed to investigate cardiovascular, autonomic and oxidative parameters after selective NOS inhibition. A spectral analysis of systolic arterial pressure (SAP) and heart rate variability (HRV) was performed...
July 28, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28756985/concomitant-epstein-barr-virus-associated-smooth-muscle-tumor-and-granulomatous-inflammation-of-the-liver
#17
Nhu Thuy Can, James P Grenert, Poonam Vohra
Epstein-Barr Virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor typically seen in immunocompromised patients. Here, we report a case of EBV-SMT and associated granulomatous inflammation in the liver of a 32-year-old man with history of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). To our knowledge, an association of these two lesions has not been previously reported. We review the literature and discuss pathogenesis, differential diagnosis and immunohistochemical (IHC) stains helpful for the diagnosis of this rare entity...
July 13, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28748455/resection-of-rectal-cancer-resembling-submucosal-tumor-that-was-preoperatively-diagnosed-with-endoscopic-ultrasound-guided-biopsy
#18
Akimitsu Tanio, Hiroaki Saito, Keigo Ashida, Shouichi Urushibara, Manabu Yamamoto, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Yoshihiko Maeta, Yoshiyuki Fujiwara
BACKGROUND: Colorectal cancer (CRC) resembling submucosal tumor (SMT; CRC/SMT) is very rare. Because its biopsy is challenging, accurate preoperative diagnosis is also very rare. CASE PRESENTATION: A 55-year-old woman with a high serum carcinoembryonic antigen level underwent a computed tomography colonoscopy, which showed extrinsic rectum compression. A coronal magnetic resonance image showed a 4-cm low-intensity tumor between her rectum and sacrum. Endoscopic ultrasound (EUS) showed a 30-mm low-echoic lesion originating from the rectum...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28727062/workload-of-official-contests-net-cost-of-transport-and-metabolic-power-of-mangalarga-marchador-horses-of-marcha-batida-or-picada-gaits
#19
J Lage, M G Fonseca, G G M de Barros, W H Feringer-Júnior, G T Pereira, G C Ferraz
This study aimed to characterize the maximum heart rate (HR) and the intensity of official marcha contests (OMC) and to compare the cost of transport (COT) and metabolic power (Pmet) of Mangalarga Marchador (MM) horses of marcha batida (MB) and marcha picada (MP) gaits. Twenty-two MM horses participated in this study. The experiment was conducted in 3 phases: 1) maximum effort test (MET), 2) OMC, and 3) standardized marcha test (SMT). To characterize the HR, 19 horses (14 MB and 5 MP) underwent a MET. Of those, 13 (9 MB and 4 MP) were monitored during the OMC, which consisted of 4 stages: marcha, walk, functional trial, and rest...
June 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28722090/-evaluation-of-a-new-closure-technique-of-large-defects-after-endoscopic-full-thickness-resection
#20
Xiao Liu, Lizhou Dou, Yong Liu, Shun He, Yueming Zhang, Xinying Yu, Yan Ke, Xudong Liu, Ruigang Wang, Guiqi Wang
OBJECTIVE: To investigate the security and efficacy of a new endoscopic closure method of large defects after endoscopic full-thickness resection (EFTR) double purse-string suture using two endoloops and metallic clips via single-channel endoscopy. METHODS: Clinical data of 23 cases with submucosal tumors (SMT) who received endoscopic resection from June 2015 to July 2016 in our National Cancer Center were collected. For gastric and esophageal SMTs or the mucosa layer injured during submucosal tunneling endoscopic resection (STER), double purse-string suture was conducted after EFTR...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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