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https://www.readbyqxmd.com/read/28523252/prevalence-of-sarcopenia-in-the-world-a-systematic-review-and-meta-analysis-of-general-population-studies
#1
REVIEW
Gita Shafiee, Abbasali Keshtkar, Akbar Soltani, Zeinab Ahadi, Bagher Larijani, Ramin Heshmat
BACKGROUND: Sarcopenia, an age-related decline in muscle mass and function, is one of the most important health problems in elderly with a high rate of adverse outcomes. However, several studies have investigated the prevalence of sarcopenia in the world, the results have been inconsistent. The current systematic review and meta- analysis study was conducted to estimate the overall prevalence of sarcopenia in both genders in different regions of the world. METHODS: Electronic databases, including MEDLINE (via PubMed), SCOPUS and Web of Science were searched between January 2009 and December 2016...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28489550/a-fully-integrated-wireless-soc-for-motor-function-recovery-after-spinal-cord-injury
#2
Yi-Kai Lo, Yen-Cheng Kuan, Stanislav Culaclii, Brian Kim, Po-Min Wang, Chih-Wei Chang, Jonathan A Massachi, Minji Zhu, Kuanfu Chen, Parag Gad, V Reggie Edgerton, Wentai Liu
This paper presents a wirelessly powered, fully integrated system-on-a-chip (SoC) supporting 160-channel stimulation, 16-channel recording, and 48-channel bio-impedance characterization to enable partial motor function recovery through epidural spinal cord electrical stimulation. A wireless transceiver is designed to support quasi full-duplex data telemetry at a data rate of 2 Mb/s. Furthermore, a unique in situ bio-impedance characterization scheme based on time-domain analysis is implemented to derive the Randles cell electrode model of the electrode-electrolyte interface...
May 5, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28485143/charge-directed-immobilization-of-bacteriophage-on-nanostructured-electrode-for-whole-cell-electrochemical-biosensors
#3
Yan Zhou, Abhijit Marar, Peter Kner, Ramaraja Pandian Ramasamy
A new type of carbon nanotube (CNT)-based impedimetric biosensing method has been developed for rapid and selective detection of live bacterial cells. Proof of concept study was conducted using T2 bacteriophage-based biosensors for electrochemical detection of Escherichia coli B. The T2 bacteriophage (virus) served as the bio-recognition element, which was immobilized on polyethylenimine (PEI)-functionalized carbon nanotube transducer on glassy carbon electrode. Charge-directed, orientated immobilization of bacteriophage particles on carbon nanotubes was achieved through covalent linkage of phage capsid onto the carbon nanotubes...
May 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28482488/direct-bioactive-ceramics-coating-via-reactive-growing-integration-layer-method-on-%C3%AE-ti-alloy
#4
Chi-Huang Huang, Rong-Sheng Chen, Masahiro Yoshimura
This paper demonstrates Ca-P-rich bio-ceramic and hydroxyapatite (HA) coatings formed directly from the solution of calcium acetate (CA) and sodium dihydrogen phosphate (SDP) on α-Ti-alloy substrates by Growing Integration Layer (GIL) technology under DC power supply. The composition of the α-Ti-alloy was Ti7Cu5Sn. The GIL coated films formed in 30min time with different voltages applied had porous and rough ceramic surfaces. They consisted mostly of various oxides like rutile, anatase, and calcium phosphates (including hydroxyapatite) that reduce corrosion rate and increase biocompatibility...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28480853/-contemporary-approach-to-diagnosis-of-subclinical-heart-failure
#5
A Azaraksh, G Ivanov, N Bulanova, L Stazhadze, M Nikolaeva, V Vostrikov
Treatment of congestive heart failure (CHF) remains one of the challenging problems in cardiology. In recent years, the method of multifrequency bio-impendancemetry is used in patients with CHF for the assessment of water imbalance and determination of its severity. The aim of the study was to determine the diagnostic capabilities of bio-impendancemetry in evaluation of the early manifestations of CHF. The study included 92 healthy individuals, and 335 patients who were hospitalized in the cardiology department with NYHA I-II functional class (FC) of chronic CHF...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28470316/top-down-fabrication-meets-bottom-up-synthesis-for-nanoelectronic-barcoding-of-microparticles
#6
Pengfei Xie, Xinnan Cao, Zhongtian Lin, Mehdi Javanmard
Traditional optical and plasmonic techniques for barcoding of micro-particles for multiplexed bioassays are generally high in throughput, however bulky instrumentation is often required for performing readout. Electrical impedance based detection allows for ultra-compact instrumentation footprint necessary for wearable devices, however to date, the lack of ability to electronically barcode micro-particles has been a long standing bottleneck towards enabling multiplexed electronic biomarker assays. Nanoelectronic barcoding, which to the best of our knowledge is the first impedance based solution for micro-particle barcoding, works by forming tunable nano-capacitors on the surface of micro-spheres, effectively modulating the frequency dependent dielectric properties of the spheres allowing one bead barcode to be distinguished from another...
May 4, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28460640/physical-performance-and-protein-energy-wasting-in-patients-treated-with-nocturnal-haemodialysis-compared-to-conventional-haemodialysis-protocol-of-the-diaprifit-study
#7
Manouk Dam, Floor Neelemaat, Trudeke Struijk-Wielinga, Peter J Weijs, Brigit C van Jaarsveld
BACKGROUND: Poor physical performance and protein-energy wasting (PEW) are health issues of major concern in haemodialysis patients. The conventional haemodialysis (CHD) regime, three times per week 3-5 h, is subject of discussion because of high morbidity and mortality rates. When patients switch from CHD to longer dialysis sessions, i.e. nocturnal haemodialysis (NHD), improvement in protein intake and increase in body weight is seen. However, it is unclear whether physical performance and more important aspects of PEW, such as body composition, improve as well...
May 1, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28449301/the-profile-and-dynamics-of-rna-modifications-in-animals
#8
Pieter van Delft, Alper Akay, Sabrina M Huber, Christoph Bueschl, Konrad L M Rudolph, Tomás Di Domenico, Rainer Schuhmacher, Eric A Miska, Shankar Balasubramanian
More than a hundred distinct modified nucleosides have been identified in RNA, but little is known about their distribution across different organisms, their dynamic nature and their response to cellular and environmental stress. Mass-spectrometry-based methods have been at the forefront of identifying and quantifying modified nucleosides. However, they often require synthetic reference standards, which do not exist in the case of many modified nucleosides, and this therefore impedes their analysis. Here we use a metabolic labelling approach to achieve rapid generation of bio-isotopologues of the complete Caenorhabditis elegans transcriptome and its modifications and use them as reference standards to characterise the RNA modification profile in this multicellular organism through an untargeted liquid-chromatography tandem high-resolution mass spectrometry (LC-HRMS) approach...
March 16, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28448273/magnetic-induction-spectroscopy-mis-probe-design-for-cervical-tissue-measurements
#9
Jau-Yi Wang, Timothy Healey, Anthony Barker, Brian Brown, Chris Monk, Dilly Anumba
OBJECTIVE: Gradiometers have the advantage of increasing measuring sensitivity, which is particularly useful in magnetic induction spectroscopy (MIS) for bio-impedance measurements. Traditional gradiometers use a pair of field sensing coils equally distant and on opposite sides of a drive coil, which provides high immunity to interference. In this paper, a ferrite-cored coaxial gradiometer probe of 29 mm diameter has been developed for measuring the impedance spectra of cervical tissues in vivo...
May 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28447434/the-influence-of-different-muscle-mass-measurements-on-the-diagnosis-of-cancer-cachexia
#10
Susanne Blauwhoff-Buskermolen, Jacqueline A E Langius, Annemarie Becker, Henk M W Verheul, Marian A E de van der Schueren
BACKGROUND: Progressive loss of muscle mass is a major characteristic of cancer cachexia. Consensus definitions for cachexia provide different options to measure muscle mass. This study describes the effect of different methods to determine muscle mass on the diagnosis of cancer cachexia. In addition, the association of cachexia with other features of cachexia, quality of life, and survival was explored. METHODS: Prior to chemotherapy, cachexia was assessed by weight loss, body mass index, and muscle mass measurements, the latter by mid-upper arm muscle area (MUAMA), computed tomography (CT) scans, and bio-electrical impedance analysis (BIA)...
April 26, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28446134/assessment-of-perioperative-minute-ventilation-in-obese-versus-non-obese-patients-with-a-non-invasive-respiratory-volume-monitor
#11
Jaideep H Mehta, Davide Cattano, Jordan B Brayanov, Edward E George
BACKGROUND: Monitoring the adequacy of spontaneous breathing is a major patient safety concern in the post-operative setting. Monitoring is particularly important for obese patients, who are at a higher risk for post-surgical respiratory complications and often have increased metabolic demand due to excess weight. Here we used a novel, noninvasive Respiratory Volume Monitor (RVM) to monitor ventilation in both obese and non-obese orthopedic patients throughout their perioperative course, in order to develop better monitoring strategies...
April 26, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28433920/proteomic-analysis-of-sockeye-salmon-serum-as-a-tool-for-biomarker-discovery-and-new-insight-into-the-sublethal-toxicity-of-diluted-bitumen
#12
Sarah L Alderman, Laura A Dindia, Christopher J Kennedy, Anthony P Farrell, Todd E Gillis
Pipelines carrying diluted bitumen (dilbit) from Canada's oil sands traverse North America, including the freshwater habitat of Pacific salmon, posing a risk of environmental release and aquatic exposure. Swimming performance is impacted in juvenile sockeye (Oncorhynchus nerka) exposed to dilbit; therefore biomarkers of dilbit exposure will be valuable for monitoring at-risk salmon stocks. This study characterized changes in the serum proteome of sockeye exposed to a sub-lethal and environmentally relevant concentration of dilbit using isobaric tags for relative and absolute quantitation (iTRAQ), and included a range of experimental conditions to permit identification of biomarkers that are robust across time (1 and 4wk) and exercise level (at rest and following a swim test)...
April 12, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/28381339/association-of-mortality-and-phase-angle-measured-by-different-bioelectrical-impedance-analysis-bia-devices
#13
Laurence Genton, François R Herrmann, Adrian Spörri, Christophe E Graf
PURPOSE: A high phase angle measured by the Nutriguard(®) bioelectrical impedance analysis device is associated with a reduced mortality risk in older people. This retrospective study aims to analyze whether this association persists with the other devices that have been used in our hospital. METHODS: This study encompasses all people 65 yrs and older who underwent a phase angle measurement between 1990 and 2011 at the Geneva University Hospitals, with the RJL-101(®) (RJL Systems), Xitron 4000B(®) (Xitron Technologies), Eugedia(®) (Eugédia-Spengler) and Bio-Z(®) (Spengler)...
March 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28376036/evaluation-of-skeletal-muscle-function-in-lung-transplant-candidates
#14
Dmitry Rozenberg, Lianne G Singer, Margaret Herridge, Roger Goldstein, Lisa Wickerson, Noori A Chowdhury, Sunita Mathur
BACKGROUND: Lung transplantation (LTx) is offered to older and more complex patients who may be at higher risk of skeletal muscle dysfunction, but the clinical implications of this remain uncertain. The study aims were to characterize deficits in skeletal muscle mass, strength and physical performance and examine the associations of these deficits with clinical outcomes. METHODS: Fifty LTx candidates (58% male, 59 ± 9 years) were prospectively evaluated for skeletal muscle deficits: muscle mass using bio-electrical impedance, quadriceps, respiratory muscle and handgrip strength, and physical performance with the Short Physical Performance Battery...
April 3, 2017: Transplantation
https://www.readbyqxmd.com/read/28371518/clinical-utility-of-bioimpedance-analysis-in-liver-cirrhosis
#15
Hiroki Nishikawa, Hirayuki Enomoto, Yoshinori Iwata, Takashi Nishimura, Hiroko Iijima, Shuhei Nishiguchi
BACKGROUND: The objective of the present study was to examine the impact of muscle mass depletion (MMD) as determined by data in bioimpedance analysis (BIA) in liver cirrhosis (LC) patients (n = 382, 204 in male and 178 in female) on survival and to validate the utility of cutoff values in BIA recommended from current recommendations. METHODS: Muscle mass depletion was defined as patients with skeletal muscle mass index (SMI) using BIA <7.0 cm(2) /m(2) for male and <5...
March 31, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28349621/-it-feels-sometimes-like-my-house-has-burnt-down-but-i-can-see-the-sky-a-qualitative-study-exploring-patients-views-of-cognitive-behavioural-therapy-for-chronic-fatigue-syndrome
#16
Federica Picariello, Sheila Ali, Caroline Foubister, Trudie Chalder
OBJECTIVES: Cognitive behavioural therapy (CBT) is currently a first-line treatment for chronic fatigue syndrome (CFS). Even though the results from trials are promising, there is variability in patient outcomes. The aim of this study was to explore the experiences of patients with CFS who undertook CBT at a specialist service for CFS. DESIGN: This was a qualitative study. METHODS: Thirteen patients with CFS, approaching the end of CBT, participated in semi-structured interviews...
March 28, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28323272/constipation-predominant-irritable-bowel-syndrome-females-have-normal-colonic-barrier-and-secretory-function
#17
Stephanie A Peters, Shoko Edogawa, Wendy J Sundt, Roy B Dyer, Daniel A Dalenberg, Amelia Mazzone, Ravinder J Singh, Natalie Moses, Thomas C Smyrk, Christopher Weber, David R Linden, Wallace K MacNaughton, Jerrold R Turner, Michael Camilleri, David A Katzka, Gianrico Farrugia, Madhusudan Grover
OBJECTIVES: The objective of this study was to determine whether constipation-predominant irritable bowel syndrome (IBS-C) is associated with changes in intestinal barrier and secretory function. METHODS: A total of 19 IBS-C patients and 18 healthy volunteers (all females) underwent saccharide excretion assay (0.1 g (13)C mannitol and 1 g lactulose), measurements of duodenal and colonic mucosal barrier (transmucosal resistance (TMR), macromolecular and Escherichia coli Bio-Particle translocation), mucosal secretion (basal and acetylcholine (Ach)-evoked short-circuit current (Isc)), in vivo duodenal mucosal impedance, circulating endotoxins, and colonic tight junction gene expression...
March 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28319904/sensitivity-enhancement-of-graphene-zinc-oxide-nanocomposite-based-electrochemical-impedance-genosensor-for-single-stranded-rna-detection
#18
Sze Shin Low, Hwei-San Loh, Jian Sheng Boey, Poi Sim Khiew, Wee Siong Chiu, Michelle T T Tan
An efficient electrochemical impedance genosensing platform has been constructed based on graphene/zinc oxide nanocomposite produced via a facile and green approach. Highly pristine graphene was synthesised from graphite through liquid phase sonication and then mixed with zinc acetate hexahydrate for the synthesis of graphene/zinc oxide nanocomposite by solvothermal growth. The as-synthesised graphene/zinc oxide nanocomposite was characterised with scanning electron microscopy (SEM), transmission electron microscopy (TEM), Raman spectroscopy and X-ray diffractometry (XRD) to evaluate its morphology, crystallinity, composition and purity...
February 27, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28299684/bacterial-detection-using-peptide-based-platform-and-impedance-spectroscopy
#19
Hashem Etayash, Thomas Thundat, Kamaljit Kaur
Antimicrobial peptides have the ability to function as bio-recognition elements in the detection of bacteria. For instance, we showed that Leucocin A, an antimicrobial peptide from class IIa bacteriocins, binds gram-positive Listeria monocytogenes with higher affinity than other gram-positive bacteria like S. aureus, L. innocua, and E. faecalis. The binding was detected using impedance spectroscopy when Leucocin A immobilized on impedance electrodes binds bacteria from a sample. Here we highlight the strength of utilizing Leucocin A as a bio-recognition probe in biosensor platforms and provide details on its application in real-time bacterial detection using electrochemical impedance spectroscopy...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28295907/the-effects-of-short-term-omission-of-daily-medication-on-the-pathophysiology-of-heart-failure
#20
Silviu Dovancescu, Pierpaolo Pellicori, Thato Mabote, Azam Torabi, Andrew L Clark, John G F Cleland
AIMS: Pharmacological therapies for heart failure (HF) aim to improve congestion, symptoms, and prognosis. Failing to take medication is a potential cause of worsening HF. Characterizing the effects of short-term medication omission could inform the development of better technologies and strategies to detect and interpret the reasons for worsening HF. We examined the effect of planned HF medication omission for 48 h on weight, echocardiograms, transthoracic bio-impedance, and plasma concentrations of NT-proBNP...
May 2017: European Journal of Heart Failure
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