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https://www.readbyqxmd.com/read/29276901/-prognostic-role-of-body-composition-in-patients-with-pneumonia-associated-with-decompensated-chf
#1
N A Bylova, G P Arutyunov, A K Rylova, A S Simbirtseva, A G Arutyunov
AIM: To evaluate the effect of body composition on prediction of community-acquired pneumonia caused by Str. pneumoniae in patients with decompensated CHF. MATERIALS AND METHODS: The study included 216 patients. The pneumonia agent was identified by sputum culture. Body composition with determining lean body mass and fat mass was evaluated using a bio-impedance analysis; body mass index (BMI) was calculated. Patients with BMI 18.5-24.9 kg/m2 were included into the study...
2017: Kardiologiia
https://www.readbyqxmd.com/read/29250633/in-situ-probing-electronic-dynamics-at-organic-bulk-heterojunction-aqueous-electrolyte-interfaces-by-charge-modulation-spectroscopy
#2
Haihua Xu, Ying Lv, Yongchun Deng, Qingqing Zhu
Interfacing an organic bulk heterojunction (OBHJ) with an aqueous electrolyte (aqE) solution has the potential for applications in biological sensing and neuronal stimulus, by taking advantage of the benefits of the high excitation efficiency and biocompatibility of the OBHJ. At the OBHJ/aqE interface, local charge transfer and transport processes, which are influenced by the polymer/fullerene interface and ion migration, are critically important for device performance but poorly understood. Here, we have introduced charge modulation spectroscopy (CMS) in aqE-gated heterojunction transistors to in situ investigate electronic dynamics at the OBHJ/aqE interface...
December 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29241303/body-fluid-status-assessment-by-bio-impedance-analysis-in-patients-presenting-to-the-emergency-department-with-dyspnea
#3
Chan Soon Park, Sang-Eun Lee, Hyun-Jai Cho, Yong-Jin Kim, Hyun-Jae Kang, Byung-Hee Oh, Hae-Young Lee
Background/Aims: Fluid retention occurs in patients with heart failure, accounting for dyspnea. We investigated the diagnostic implication of body fluid status, assessed by bio-impedance analysis (BIA), in acute heart failure (AHF) among patients who presented with dyspnea. Methods: A total of 100 patients who presented with dyspnea and suspected with AHF were analyzed in this study. We enrolled 50 AHF and 50 non-AHF patients discriminated through echocardiographic analysis and Framingham criteria and were matched by age and sex...
December 18, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29215565/a-miniaturized-impedimetric-immunosensor-for-the-competitive-detection-of-adrenocorticotropic-hormone
#4
Nan Li, Egor M Larin, Kagan Kerman
Adrenocorticotropic hormone (ACTH) plays an essential role in regulating corticosteroid hormone production, which has important functions in a myriad of critical physiological functions. In this proof-of-concept study, a miniaturized immunosensor was developed for the highly sensitive detection of ACTH using electrochemical impedance spectroscopy (EIS) in connection with disposable screen-printed gold electrodes (SPGEs). A film of 3,3'-dithiobis[sulfosuccinimidylpropionate] (DTSSP) was prepared to immobilize anti-ACTH antibodies covalently on the nanostructured SPGE surface...
December 7, 2017: Sensors
https://www.readbyqxmd.com/read/29182192/-effects-of-high-intensity-interval-training-and-nutritional-education-in-patients-with-type-2-diabetes
#5
Pedro Mangiamarchi, Alexis Caniuqueo, Rodrigo Ramírez-Campillo, Patricio Cárdenas, Sylvana Morales, Johnattan Cano-Montoya, Guilherme Bresciani, Cristian Álvarez
BACKGROUND: High-intensity interval training (HIIT) improves cardiometabolic markers, but its effects on the quality of life of patients with type 2 diabetes (T2D) is not well known. AIM: To determine the effects of a 12-week HIIT exercise program on cardiometabolic and quality of life variables of T2D patients. MATERIAL AND METHODS: Nine T2D women were assigned to a HIIT + nutritional education (GE) and 10, to a nutritional education alone group (GC)...
July 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29154792/robust-real-time-cell-analysis-method-for-determining-viral-infectious-titers-during-development-of-a-viral-vaccine-production-process
#6
Cédric Charretier, Aure Saulnier, Loïc Benair, Corinne Armanet, Isabelle Bassard, Sandra Daulon, Bertrand Bernigaud, Emanuel Rodrigues de Sousa, Clémence Gonthier, Edouard Zorn, Emmanuelle Vetter, Claire Saintpierre, Patrice Riou, David Gaillac
The classical cell-culture methods, such as cell culture infectious dose 50% (CCID50) assays, are time-consuming, end-point assays currently used during the development of a viral vaccine production process to measure viral infectious titers. However, they are not suitable for handling the large number of tests required for high-throughput and large-scale screening analyses. Impedance-based bio-sensing techniques used in real-time cell analysis (RTCA) to assess cell layer biological status in vitro, provide real-time data...
November 14, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/29127898/capacitive-aptasensor-based-on-interdigitated-electrode-for-breast-cancer-detection-in-undiluted-human-serum
#7
Sunil K Arya, Pavel Zhurauski, Pawan Jolly, Marina R Batistuti, Marcelo Mulato, Pedro Estrela
We report the development of a simple and powerful capacitive aptasensor for the detection and estimation of human epidermal growth factor receptor 2 (HER2), a biomarker for breast cancer, in undiluted serum. The study involves the incorporation of interdigitated gold electrodes, which were used to prepare the electrochemical platform. A thiol terminated DNA aptamer with affinity for HER2 was used to prepare the bio-recognition layer via self-assembly on interdigitated gold surfaces. Non-specific binding was prevented by blocking free spaces on surface via starting block phosphate buffer saline-tween20 blocker...
November 8, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29126108/laboratory-scale-photobiotechnology-current-trends-and-future-perspectives
#8
Holger Morschett, Varun Loomba, Gregor Huber, Wolfgang Wiechert, Eric von Lieres, Marco Oldiges
Phototrophic bioprocesses are a promising puzzle piece in future bio-economy concepts but mostly fail for economic reasons, yet. Besides other aspects, this is mainly attributed to the omnipresent issue of optimal light supply impeding scale-up and -down of phototrophic processes according to classic established concepts. This MiniReview examines two current trends in photobiotechnology, namely microscale cultivation and modeling and simulation. Micro photobioreactors are a valuable and promising trend with microfluidic chips and microtiter plates as predominant design concepts...
November 8, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29109091/transcriptomic-profiling-of-mda-mb-231-cells-exposed-to-boswellia-serrata-and-3-o-acetyl-b-boswellic-acid-er-upr-mediated-programmed-cell-death
#9
REVIEW
Elizabeth A Mazzio, Charles A Lewis, Karam F A Soliman
BACKGROUND/AIM: Triple-negative breast cancer (TNBC) is characterized by the absence of hormone receptors (estrogen, progesterone and human epidermal growth factor receptor-2) and a relatively poor prognosis due to inefficacy of hormone receptor-based chemotherapies. It is imperative that we continue to explore natural products with potential to impede growth and metastasis of TNBC. In this study, we screened over 1,000 natural products for capacity to induce cell death in TNBC (MDA-MB -231) cells...
November 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/29083445/the-gene-diet-associations-in-postmenopausal-women-with-newly-diagnosed-dyslipidemia
#10
B Grygiel-Górniak, E Kaczmarek, M Mosor, J Przysławski, J Nowak
OBJECTIVES: The aim of this study was to determine the relationship between polymorphisms of peroxisome proliferator activated receptor - PPAR gamma-2 (Pro12Ala, C1431T) and beta 3-adrenergic receptor - ADRB3 (Trp64Arg) and dietary habits in a group of postmenopausal women who were not under hypolipidemic treatment. DESIGN: Genetic, nutritional and anthropometric parameters were measured in 213 dyslipidemic (LDL ≥115 mg/dL) and 58 normolipidemic (LDL<115) postmenopausal women...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29083144/enhanced-cell-chip-coupling-by-rapid-femtosecond-laser-patterning-of-soft-pedot-pss-biointerfaces
#11
Francesca Santoro, Yoeri van de Burgt, Scott Tom Keene, Bianxiao Cui, Alberto Salleo
Interfacing soft materials with biological systems holds considerable promise for both biosensors and recording live cells. However, the interface between cells and organic substrates is not well studied, despite its crucial role in the effectiveness of the device. Furthermore, well-known cell adhesion enhancers, such as microgrooves, have not been implemented on these surfaces. Here, we present a nanoscale characterization of the cell-substrate interface for 3D laser-patterned organic electrodes by combining electrochemical impedance spectroscopy (EIS) and scanning electron microscopy/focused ion beam (SEM/FIB)...
November 2, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29073520/label-free-biosensors-in-the-field-of-stem-cell-biology
#12
REVIEW
Farzaneh Fathi, Reza Rahbarghazi, Mohammad-Reza Rashidi
A great body of evidence unveiled the existence of different stem cell types in various tissues with efficient capability for self-renewal and differentiation. Characterization and enumeration of a specific stem cell population seem difficult because these cells consist of a small percentage of cells within different milieu. As such, due to lack of accuracy provided by convenient methods, biosensing techniques are at the center of attention to improve stem cells characterization with high rate of sensitivity and specificity...
March 15, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29072035/relation-between-lifestyle-behaviors-and-body-composition-patterns-among-healthy-young-italians-a-cross-sectional-study
#13
Luciana Zaccagni, Natascia Rinaldo, Barbara Bramanti, Emanuela Gualdi-Russo
BACKGROUND: Negative lifestyle factors affect health outcomes adversely. The aim of the study was to assess body composition parameters and their relationship to several lifestyle behaviors among young Italian adults. METHODS: A cross sectional study was carried out on a sample of university students (n= 200; 50% males; 21.9 ± 2.0 years). Anthropometric and bio-impedance traits were directly measured. Behavioral data (physical activity, alcohol consumption and smoking data) were collected by a self- administered questionnaire...
October 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29060300/exploration-and-validation-of-alternate-sensing-methods-for-wearable-continuous-pulse-transit-time-measurement-using-optical-and-bioimpedance-modalities
#14
Bassem Ibrahim, Viswam Nathan, Roozbeh Jafari
In this work we explore the viability of a multimodal sensing device that can be integrated in a wearable form factor for daily, non-invasive ambulatory blood pressure (BP) monitoring. A common approach in previous research has been to rely on measuring the pulse transit time (PTT), which has been shown to be correlated with the BP. In this work, we look into the feasibility of measuring PTT using sensors separated by a small distance on one arm so that any eventual realization of the system is convenient to wear and use over long periods of time...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060187/micro-patterned-films-of-bio-functionalized-conducting-polymers-for-cellular-engineering
#15
SooHyun Park, Mohammad R Abidian, Sheereen Majd
Conducting polymers (CPs) are easy to process and have tunable physical and chemical properties including conductivity, volume, color, and hydrophobicity. Therefore, these organic polymers are attractive in a broad spectrum of bioelectronic applications ranging from implantable electrodes to biosensors and actuators. Patterned films of CPs, especially with various surface chemistries, provide versatile and sophisticated building-blocks for bioelectronics. In this context, we recently introduced a simple and efficient technique of hydrogel-mediated electropolymerization to directly pattern films of PPy (polypyrrole) with spatially-addressable chemistries...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057827/predictors-associated-with-increase-in-skeletal-muscle-mass-after-sustained-virological-response-in-chronic-hepatitis-c-treated-with-direct-acting-antivirals
#16
Kazunori Yoh, Hiroki Nishikawa, Hirayuki Enomoto, Akio Ishii, Yoshinori Iwata, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Ryo Takata, Hiroko Iijima, Shuhei Nishiguchi
AIMS: We aimed to examine changes in skeletal muscle mass in chronic hepatitis C (CHC) patients undergoing interferon (IFN)-free direct acting antivirals (DAAs) therapy who achieved sustained virological response (SVR). PATIENTS AND METHODS: A total of 69 CHC patients treated with DAAs were analyzed. We compared the changes in skeletal muscle index (SMI) using bio-impedance analysis at baseline and SMI at SVR. SMI was calculated as the sum of skeletal muscle mass in upper and lower extremities divided by height squared (cm²/m²)...
October 18, 2017: Nutrients
https://www.readbyqxmd.com/read/29056754/subcutaneous-photovoltaic-infrared-energy-harvesting-for-bio-implantable-devices
#17
Eunseong Moon, David Blaauw, Jamie D Phillips
Wireless biomedical implantable devices on the mm-scale enable a wide range of applications for human health, safety, and identification, though energy harvesting and power generation are still looming challenges that impede their widespread application. Energy scavenging approaches to power biomedical implants have included thermal [1-3], kinetic [4-6], radio-frequency [7-11] and radiative sources [12-14]. However, the achievement of efficient energy scavenging for biomedical implants at the mm-scale has been elusive...
May 2017: IEEE Transactions on Electron Devices
https://www.readbyqxmd.com/read/29048152/a-new-chemometric-approach-for-automatic-identification-of-microplastics-from-environmental-compartments-based-on-ft-ir-spectroscopy
#18
Gerrit Renner, Torsten C Schmidt, Jürgen Schram
One key step studying interactions of microplastics with our ecological system is to identify plastics within environmental samples. Aging processes and surface contamination especially with biofilms impede this characterization. A complex and time-consuming cleaning procedure is a common solution for this problem. However, it implies an artificial change of sample composition with a risk of losing important information or even damaging microplastic particles. In the present work, we introduce a new chemometric approach to identify heavily weathered and contaminated microplastics without any cleaning...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29034941/selective-photocatalysis-of-lignin-inspired-chemicals-by-integrating-hybrid-nanocatalysis-in-microfluidic-reactors
#19
Juan Carlos Colmenares, Rajender S Varma, Vaishakh Nair
This tutorial review assesses the available and possible strategies for attaining higher selectivity and yield of value-added chemicals from lignin using nanocatalysts embedded in a photomicroreactor. The design of the photomicroreactor, the choice of photocatalysts and the techniques for assembling the catalysts in such confined spaces are crucial elements. Lignin, a predominant industrial byproduct and pollutant, has been recognized today as a rich reservoir for aromatic chemicals and a prominent resource...
November 13, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29028929/peripheral-i-v-analysis-piva-of-venous-waveforms-for-volume-assessment-in-patients-undergoing-haemodialysis
#20
K M Hocking, B D Alvis, F Baudenbacher, R Boyer, C M Brophy, I Beer, S Eagle
Background: The assessment of intravascular volume status remains a challenge for clinicians. Peripheral i.v. analysis (PIVA) is a method for analysing the peripheral venous waveform that has been used to monitor volume status. We present a proof-of-concept study for evaluating the efficacy of PIVA in detecting changes in fluid volume. Methods: We enrolled 37 hospitalized patients undergoing haemodialysis (HD) as a controlled model for intravascular volume loss...
December 1, 2017: British Journal of Anaesthesia
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