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Bio impedance

Saeed Rafizadeh-Tafti, Mohammad Hossein Haqiqatkhah, Mehrdad Saviz, Mohsen Janmaleki, Reza Faraji Dana, Somayeh Zanganeh, Mohammad Abdolahad
A highly sensitive impedimetric bio-chip based on vertically aligned multiwall carbon nanotubes (VAMWCNTs), was applied in direct interaction with lung cancer cells. Our tool provided both inducing and monitoring the bioelectrical changes in the cells initiated by electromagnetic (EM) wave stimulation. EM wave of 940MHz frequency with different intensities was used. Here, wave ablation might accumulate electrical charge on the tips of nanotubes penetrated into cell's membrane. The charge might induce ionic exchanges into the cell and cause alterations in electrical states of the membrane...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
Tahereh Sabaghian, Bahareh Hajibaratali, Shiva Samavat
AIM: Bio-impedance analysis (BIA) is a preferred method for estimating the volume status. However, it cannot be utilized in daily practice. Since the assessment of the volume status is important and challenging for hemodialysis (HD) patients, the aim of study was to determine the volume status in chronic HD patients using echocardiographic parameters and assess its correlation with BIA. METHODS: In this cross-sectional analysis, echocardiography and BIA were performed on 30 chronic HD patients 30 min before and 30 min after dialysis...
October 20, 2016: Renal Failure
Mingyue Liu, Libing Wang, Renliang Huang, Yanjun Yu, Rongxin Su, Wei Qi, Zhimin He
Bionanomaterials synthesized by bio-inspired templating methods have emerged as a novel class of composite materials with varied applications in catalysis, detection, drug delivery, and biomedicine. In this study, two kinds of cross-linked lysozyme crystals (CLLCs) of different sizes were applied for the in situ growth of Au nanoparticles (AuNPs). The resulting composite materials were characterized by light microscopy, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis, and X-ray photoelectron spectroscopy...
October 8, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
Anil Koklu, Ahmet C Sabuncu, Ali Beskok
Electrode polarization at the electrolyte/electrode interface is often undesirable for bio-sensing applications, where charge accumulated over an electrode at constant potential causes large potential drop at the interface and low measurement sensitivity. In this study, novel rough electrodes were developed for decreasing electrical impedance at the interface. The electrodes were fabricated using electrochemical deposition of gold and sintering of gold nanoparticles. The performances of the gold electrodes were compared with platinum black electrodes...
July 1, 2016: Electrochimica Acta
Diana Gutiérrez, Claudio Hidalgo-Cantabrana, Ana Rodríguez, Pilar García, Patricia Ruas-Madiedo
Bacteria found in diverse ecosystems grow in a community of aggregated cells that favors their survival and colonization. Different extracellular polymeric substances are used to entrap this multispecies community forming a biofilm, which can be associated to biotic and abiotic surfaces. This widespread and successful way of bacterial life, however, can lead to negative effects for human activity since many pathogen and spoiling bacteria form biofilms which are not easy to eradicate. Therefore, the search for novel anti-biofilm bio-active molecules is a very active research area for which simple, reliable, and fast screening methods are demanded...
2016: PloS One
Maude Dulac, Guy El Hajj Boutros, Charlotte Pion, Sébastien Barbat-Artigas, Gilles Gouspillou, Mylène Aubertin-Leheudre
Objective: To investigate whether handgrip strength normalized to body weight could be a useful clinical tool to identify dynapenia and assess functional capacity in post-menopausal women. Method: A total of 136 postmenopausal women were recruited. Body composition (Dual Energy X-ray Absorptiometry [DEXA], Bio-electrical Impedence Analysis [BIA]), grip strength (dynamometer) and functional capacity (senior fitness tests) were evaluated. Dynapenia was established according to a handgrip strength index (handgrip strength divided by body weight (BW) in Kg/KgBW) obtained from a reference population of young women: Type I dynapenic (<0...
September 15, 2016: Brazilian Journal of Physical Therapy
S Vonck, J Oben, A S Staelens, D Lanssens, K Tomsin, W Gyselaers
INTRODUCTION: Maternal cardiovascular adaptations are mandatory for a normal course of pregnancy. Disturbed adaptations predispose to gestational complications further in pregnancy such as hypertension disorders and/or fetal growth restriction. We aim to explore the early gestational cardiovascular profile in uncomplicated pregnancy, in gestational hypertensive disorders and isolated intra-uterine growth retardation. METHODS: Cardiovascular assessments were done using a standard protocol with impedance cardiography (Niccomo, SonoSite, MedisMedinizinischeMesstechnik GmbH, Ilmenau, Germany) and bio-impedance (Maltron BIOSCAN 920-II; Maltron International LTD, Essex, UK) around 12 weeks of gestation...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
Suryasnata Tripathy, Aniket Ramesh Ghole, Khandavalli Deep, Siva Rama Krishna Vanjari, Shiv Govind Singh
This paper proposes a novel milk quality detection approach based on utilization of inherent biophysical properties as 'markers' for adulteration. Unlike the traditional adulterant-specific approaches, this method is generic and universal. It exploits the change in innate milk properties, such as electrical conductivity and pH, upon addition of adulterants as a transduction mechanism for detecting milk adulteration. In this work, adulteration with more than 10 commercially known hazardous adulterants is detected by monitoring the changes in milk electrical conductivity and pH...
February 15, 2017: Food Chemistry
Edlyne Anugwom, Kenechukwu Anugwom
BACKGROUND: The South-southern zone of Nigeria is one of the zones in the country that has reported consistent high prevalent rates of HIV/AIDS pandemic in the last decade. In spite of bio-medical reasons adduced for the spread of the pandemic, socio-cultural factors may be major issues in the access to both prevention and treatment services especially for women. Hence, this study investigated the socio-cultural factors, which influence the access of women to HIV/AIDS prevention and treatment services in Nigeria...
June 2016: Iranian Journal of Public Health
Martin Proença, Fabian Braun, Josep Solà, Jean-Philippe Thiran, Mathieu Lemay
Current monitoring modalities for patients with pulmonary hypertension (PH) are limited to invasive solutions. A novel approach for the noninvasive and unsupervised monitoring of pulmonary artery pressure (PAP) in patients with PH was proposed and investigated. The approach was based on the use of electrical impedance tomography (EIT), a noninvasive and safe monitoring technique, and was tested through simulations on a realistic 4D bio-impedance model of the human thorax. Changes in PAP were induced in the model by simulating multiple types of hypertensive conditions...
September 17, 2016: Medical & Biological Engineering & Computing
Nadia El Alami El Hassani, Abdoullatif Baraket, Ernandes Taveira Tenório Neto, Michael Lee, J-Pablo Salvador, M-Pilar Marco, Joan Bausells, Nezha El Bari, Benachir Bouchikhi, Abdelhamid Elaissari, Abdelhamid Errachid, Nadia Zine
Sulfapyridine (SPy) is a sulfonamide antibiotic largely employed as veterinary drugs for prophylactic and therapeutic purposes. Therefore, its spread in the food products has to be restricted. Herein, we report the synthesis and characterization of a novel electrochemical biosensor based on gold microelectrodes modified with a new structure of magnetic nanoparticles (MNPs) coated with poly(pyrrole-co-pyrrole-2-carboxylic acid) (Py/Py-COOH) for high efficient detection of SPy. This analyte was quantified through a competitive detection procedure with 5-[4-(amino)phenylsulfonamide]-5-oxopentanoic acid-BSA (SA2-BSA) antigens toward polyclonal antibody (Ab-155)...
August 27, 2016: Biosensors & Bioelectronics
Ravikumar Komandur Elayavilli, Hongfang Liu
BACKGROUND: Computational modeling of biological cascades is of great interest to quantitative biologists. Biomedical text has been a rich source for quantitative information. Gathering quantitative parameters and values from biomedical text is one significant challenge in the early steps of computational modeling as it involves huge manual effort. While automatically extracting such quantitative information from bio-medical text may offer some relief, lack of ontological representation for a subdomain serves as impedance in normalizing textual extractions to a standard representation...
2016: AMIA Summits on Translational Science Proceedings
Jerome Irianto, Charlotte R Pfeifer, Irena L Ivanovska, Joe Swift, Dennis E Discher
Dysmorphic nuclei are commonly seen in cancers and provide strong motivation for studying the main structural proteins of nuclei, the lamins, in cancer. Past studies have also demonstrated the significance of microenvironment mechanics to cancer progression, which is extremely interesting because the lamina was recently shown to be mechanosensitive. Here, we review current knowledge relating cancer progression to lamina biophysics. Lamin levels can constrain cancer cell migration in 3D and thereby impede tumor growth, and lamins can also protect a cancer cell's genome...
June 2016: Cellular and Molecular Bioengineering
Anneleen S Staelens, Sharona Vonck, Geert Molenberghs, Manu L N G Malbrain, Wilfried Gyselaers
OBJECTIVES: Body fluid composition changes during the course of pregnancy and there is evidence to suggest that these changes are different in uncomplicated pregnancies compared to hypertensive pregnancies. The aim of this study was to evaluate the changes in maternal body fluid composition during the course of an uncomplicated pregnancy and to assess differences in uncomplicated pregnancies versus hypertensive pregnancies by using a bio-impedance analysis technique. STUDY DESIGN: Body fluid composition of each patient was assessed using a multiple frequency bioelectrical impedance analyser...
September 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Nazeem Ishrat Siddiqui, Sarfaraz Alam Khan, Mohammad Shoeb, Sukhwant Bose
INTRODUCTION: Phase Angle (PhA) is a ratio of whole body reactance and resistance obtained from Bioelectrical Impedance Analysis (BIA). It indicates cellular health and integrity and is considered as prognostic tool in medical disorders. In spite of prognostic potentials of PhA, it has limited usefulness in clinical practice and in population studies because of non-availability of normal population reference limits for comparison. Moreover, it is influenced by various factors like age, sex, race and body composition (i...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Neha Bakshi, Kalyani Singh
BACKGROUND: Malnutrition is highly prevalent in patients undergoing liver transplantation and has been associated to various clinical variables and outcome of the surgery. METHODS: We recruited 54 adult patients undergoing living donor liver transplant (LT) as study sample. Nutrition assessment was performed by body mass index (BMI), BMI for ascites, albumin, subjective global assessment (SGA) and anthropometry [mid upper arm circumference (MUAC), mid arm muscle circumference (MAMC), and triceps skin-fold (TSF)], Hand Grip strength, and phase angle of the body...
August 2016: Hepatobiliary Surgery and Nutrition
Syo Nakajima, Koichi Watashi, Hirofumi Ohashi, Shinji Kamisuki, Jesus Izaguirre-Carbonell, Andrew Tae-Jun Kwon, Harukazu Suzuki, Michiyo Kataoka, Senko Tsukuda, Maiko Okada, Meng Ling Moi, Toshifumi Takeuchi, Minetaro Arita, Ryosuke Suzuki, Hideki Aizaki, Takanobu Kato, Tadaki Suzuki, Hideki Hasegawa, Tomohiko Takasaki, Fumio Sugawara, Takaji Wakita
UNLABELLED: Cell culture systems reproducing virus replication can serve as unique models for the discovery of novel bioactive molecules. Here, using a hepatitis C virus (HCV) cell culture system, we identified neoechinulin B (NeoB), a fungus-derived compound, as an inhibitor of the liver X receptor (LXR). NeoB was initially identified by chemical screening as a compound that impeded the production of infectious HCV. Genome-wide transcriptome analysis and reporter assays revealed that NeoB specifically inhibits LXR-mediated transcription...
October 15, 2016: Journal of Virology
Bishnu Kumar Shrestha, Rafiq Ahmad, Hamouda M Mousa, In-Gi Kim, Jeong In Kim, Madhav Prasad Neupane, Chan Hee Park, Cheol Sang Kim
A highly electroactive bio-nanohybrid film of polypyrrole (PPy)-Nafion (Nf)-functionalized multi-walled carbon nanotubes (fMWCNTs) nanocomposite was prepared on the glassy carbon electrode (GCE) by a facile one-step electrochemical polymerization technique followed by chitosan-glucose oxidase (CH-GOx) immobilization on its surface to achieve a high-performance glucose biosensor. The as-fabricated nanohybrid composite provides high surface area for GOx immobilization and thus enhances the enzyme-loading efficiency...
November 15, 2016: Journal of Colloid and Interface Science
Tim J T Sutherland, Christene R McLachlan, Malcolm R Sears, Richie Poulton, Robert J Hancox
The relationship between adiposity and respiratory function is poorly understood. Most studies investigating this have used indirect measures of body fat and few have assessed how changes in adiposity influence lung function.Body fat measured by bio-electrical impedance analysis, body mass index, waist circumference, spirometry, body plethysmography and transfer factor were measured at ages 32 and 38 years in 361 non-smoking, non-asthmatic participants from a population-based birth cohort.Higher percentage body fat was associated with lower spirometric and plethysmographic lung volumes, but not with airflow obstruction, or transfer factor at 32 years...
September 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Xin Zhang, Wei Tang, Gang Chen, Fanghui Ren, Haiwei Liang, Yiwu Dang, Minhua Rong
OBJECTIVES: Previous studies have demonstrated that microRNA-132 plays a vital part in and is actively associated with several cancers, with its tumor-suppressive role in hepatocellular carcinoma confirmed. The current study employed multiple bioinformatics techniques to establish gene signatures for hepatocellular carcinoma, microRNA-132 predicted target genes and the corresponding overlaps. METHODS: Various assays were performed to explore the role and cellular functions of miR-132 in HCC and a successive panel of tasks was completed, including NLP analysis, miR-132 target genes prediction, comprehensive analyses (gene ontology analysis, pathway analysis, network analysis and connectivity analysis), and analytical integration...
2016: PloS One
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