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Bio impedance

Karsten Königstein, Denis Infanger, Christopher Klenk, Timo Hinrichs, Anja Rossmeissl, Sandra Baumann, Benjamin Hafner, Henner Hanssen, Arno Schmidt-Trucksäss
BACKGROUND AND AIMS: Higher cardiorespiratory fitness is associated with lower pulse wave velocity and arterial stiffness in normal weight individuals, and this has not been examined in obese individuals. It is unclear whether an altered body composition acts as a modifier of the association between cardiorespiratory fitness and arterial stiffness. We examined the association between peak oxygen uptake and brachial-ankle pulse wave velocity and analysed whether body composition attenuates this association in obese middle-aged individuals...
March 8, 2018: Atherosclerosis
Katherine D Hills, Daniela A Oliveira, Nicholas D Cavallaro, Carmen L Gomes, Eric S McLamore
We demonstrate a sensing mechanism for rapid detection of Listeria monocytogenes in food samples using the actuation of chitosan-aptamer nanobrush borders. The bio-inspired soft material and sensing strategy mimic natural symbiotic systems, where low levels of bacteria are selectively captured from complex matrices. To engineer this biomimetic system, we first develop reduced graphene oxide/nanoplatinum (rGO-nPt) electrodes, and characterize the fundamental electrochemical behavior in the presence and absence of chitosan nanobrushes during actuation (pH-stimulated osmotic swelling)...
March 15, 2018: Analyst
Hiang Kwee Lee, Charlynn Sher Lin Koh, Yih Hong Lee, Chong Liu, In Yee Phang, Xuemei Han, Chia-Kuang Tsung, Xing Yi Ling
Electrochemical nitrogen-to-ammonia fixation is emerging as a sustainable strategy to tackle the hydrogen- and energy-intensive operations by Haber-Bosch process for ammonia production. However, current electrochemical nitrogen reduction reaction (NRR) progress is impeded by overwhelming competition from the hydrogen evolution reaction (HER) across all traditional NRR catalysts and the requirement for elevated temperature/pressure. We achieve both excellent NRR selectivity (~90%) and a significant boost to Faradic efficiency by 10 percentage points even at ambient operations by coating a superhydrophobic metal-organic framework (MOF) layer over the NRR electrocatalyst...
March 2018: Science Advances
Chengquan Wang, Jing Qian, Keqi An, Chanchan Ren, Xiaoting Lu, Nan Hao, Qian Liu, Henan Li, Xingyi Huang, Kun Wang
Aflatoxin B1 (AFB1), one of the most common mycotoxins in food matrixes, has been identified as the most toxic contaminant with mutagenic, teratogenic, immunosuppressive, and carcinogenic effects. In this work, a magnetically assembled aptasensing device has been designed for label-free determination of AFB1 by employing a disposable screen-printed carbon electrode (SPCE) covered with a designed polydimethylsiloxane (PDMS) film as the micro electrolytic cell. The magnetically controlled bio-probes were firstly prepared by immobilization of the thiolated aptamers on the Fe3 O4 @Au magnetic beads, which was rapidly assembled on the working electrode of SPCE within 10 s, by using a magnet placed at the opposite side...
February 28, 2018: Biosensors & Bioelectronics
Yuxiang Chen, Jie Li, Yanqing Lai, Ming Xu, Junming Li, Peng Wang, Zhian Zhang
As low cost substitute of graphene and graphene-derivative, 2D carbon nanosheets are considered as attractive materials for high-performance electrochemical energy storage devices. Nevertheless, the lack of cost-effective and green preparation method still greatly impeded the application of 2D carbon nanosheets in sodium ion battery. Herein, an environmental friendly and versatile strategy is proposed to engineer anisotropically curved N-doped carbon nanosheets (CNCNs) derived from bio-source with hydrosoluble and recyclable flux...
February 28, 2018: ChemSusChem
Hye Jin Kang, Dae Won Jun, Seung Min Lee, Eun Chul Jang, Yong Kyun Cho
Background: Recent several observational studies have reported that high salt intake is associated with obesity. But it is unclear whether salt intake itself induce obesity or low salt diet can reduce body fat mass. We investigated whether a low salt diet can reduce body weight and fat amount. Matrials and Methods: The randomized, open-label pilot trial was conducted at a single institution. A total of 85 obese people were enrolled. All participants were served meals three times a day, and provided either a low salt diet or control diet with same calorie...
February 2, 2018: Oncotarget
Pavel Zhurauski, Sunil K Arya, Pawan Jolly, Christian Tiede, Darren C Tomlinson, Paul Ko Ferrigno, Pedro Estrela
A novel Affimer-functionalised interdigitated electrode-based capacitive biosensor platform was developed for detection and estimation of Her4, a protein tumour biomarker, in undiluted serum. An anti-Her4 Affimer with a C-terminal cysteine was used to create the bio-recognition layer via self-assembly on gold interdigitated electrodes for the sensor fabrication. Electrochemical impedance spectroscopy (EIS) in the absence of redox markers was used to evaluate the sensor performance by monitoring the changes in capacitance...
February 21, 2018: Biosensors & Bioelectronics
Hanneke Buter, Janny A Veenstra, Matty Koopmans, Christiaan E Boerma
INTRODUCTION: Malnutrition at the time of ICU admission is associated with an increased morbidity and mortality. Malnutrition is most often assessed by a questionnaire but can also be determined with bio-impedance and measurement of phase angle. In a single-centre observational study we compared the percentage of malnutrition in patients admitted to our ICU, according to the Short Nutritional Assessment Questionnaire (SNAQ) with the phase angle measured with bio-impedance. Furthermore, we questioned whether malnutrition is related to outcome parameters...
February 2018: Clinical Nutrition ESPEN
Lidan Hu, Peiyuan Wang, Mengyao Zhao, Lu Liu, Lei Zhou, Benhao Li, Fahad H Albaqami, Ahmed Mohamed El-Toni, Xiaomin Li, Yang Xie, Xiaofei Sun, Fan Zhang
As a minimal or noninvasive therapeutic method for tumors, photodynamic therapy (PDT) induced by the external laser irradiations has attracted great attentions. However, the UV-visible responsive property with low tissue penetration and photothermal effect from the prolonged irradiation impedes their further applications. Herein, a near-infrared (NIR) rechargeable "optical battery" for irradiation-free PDT is fabricated by embedding upconversion materials, persistent luminescence materials, photosensitizer into biocompatible polydimethylsiloxane...
May 2018: Biomaterials
Geetha Priyadarshini Badhirappan, Vignesh Nallasivam, Madhuri Varadarajan, Vasantha Priya Leobeemrao, Sivakumar Bose, Elakkiya Venugopal, Selvakumar Rajendran, Peter Chrysologue Angleo
Nano-crystalline Zrx-Cu100-x (x = 20-100 at.%) thin films with thickness ranging from 50 to 185 nm were deposited by magnetron co-sputtering with individual Zr and Cu targets. The as-sputtered thin films were characterized by Field Emission Scanning Electron Microscope (FE-SEM), Atomic Force Microscopy (AFM) and Glancing Incidence X-ray Diffraction (GIXRD) for structural and morphological properties. The crystallite size was found to decrease from 57 nm to 37 nm upon increasing the Zr content from 20 to 30 at...
July 1, 2018: Journal of Nanoscience and Nanotechnology
Vijay K Singh, Saurabh Kumar, Sumit Kumar Pandey, Saurabh Srivastava, Monu Mishra, Govind Gupta, B D Malhotra, R S Tiwari, Anchal Srivastava
Motivation behind the present work is to fabricate a cost effective and scalable biosensing platform for an easy and reliable detection of cancer biomarker Carcinoembryonic antigen (CEA). Here, we report the sensitive and selective detection of CEA using graphene based bio-sensing platform. Large sized (~ 2.5 × 1.0cm2), uniform, continuous, single and few layers graphene films have been grown on copper (Cu) substrate employing chemical vapor deposition (CVD) technique using hexane as a liquid precursor. Functional group has been created over Graphene/Cu substrate through π-π stacking of 1- pyrenebutanoic acid succinimidyl ester (PBSE)...
May 15, 2018: Biosensors & Bioelectronics
Zheng He Wang, Zhong Ping Yang, Xi Jie Wang, Yan Hui Dong, Jun Ma
To examine accuracy of body composition predicted by the Multi-Frequency Bioelectric Impedance Analysis (MF-BIA) compared with the Dual-energy X-ray Absorptiometry (DXA) in adults with obese. We measured body composition of 749 adults with obese both by the MF-BIA and DXA. The Lin's concordance correlation and the Bland-Altman plots were used to examine the consistency. The concordance correlation coefficient of %BF between the MF-BIA and DXA in men and women was 0.560, and 0.669, respectively. Compared with the DXA, the MF-BIA significantly underestimated %BF by 4...
January 2018: Biomedical and Environmental Sciences: BES
Mario Urso, Giovanna Pellegrino, Vincenzina Strano, Elena Bruno, Francesco Priolo, Salvatore Salvo Mirabella
Ni based nanostructures are attractive catalytic materials for many electrochemical applications among which non-enzymatic sensing, charge storage, water splitting. In this work, we clarify the synthesis kinetics of Ni(OH)<sub>2</sub>/NiOOH nanowalls grown by chemical bath deposition at room temperature and at 50 °C, and then we applied the results to non-enzymatic glucose sensing reaching the utmost sensitivity of 31 mA/(cm<sup>2</sup>mM). Using scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis and Rutherford backscattering spectrometry (RBS) we found that the growth occurs through two regimes: first, a quick random growth leading to disordered sheets of Ni oxy-hydroxide, followed by a slower growth of well-aligned sheets of Ni hydroxide...
February 2, 2018: Nanotechnology
Jahaun Azadmanesh, Gloria E O Borgstahl
Superoxide dismutases (SODs) are necessary antioxidant enzymes that protect cells from reactive oxygen species (ROS). Decreased levels of SODs or mutations that affect their catalytic activity have serious phenotypic consequences. SODs perform their bio-protective role by converting superoxide into oxygen and hydrogen peroxide by cyclic oxidation and reduction reactions with the active site metal. Mutations of SODs can cause cancer of the lung, colon, and lymphatic system, as well as neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis...
January 30, 2018: Antioxidants (Basel, Switzerland)
Milad Zamani, Yasser Rezaeiyan, Omid Shoaei, Wouter A Serdijn
This paper presents an implantable bio-impedance measurement system for cardiac pacemakers. The fully integrated system features a low power analog front-end and pulse width modulated output. The bio-impedance readout benefits from voltage to time conversion to achieve a very low power consumption for wirelessly transmitting the data outside the body. The proposed IC is fabricated in a 0.18 μm CMOS process and is capable of measuring the bio-impedance at 2 kHz over a wide dynamic range from to with accuracy and maximum current injection while consuming just from a 1 V supply...
February 2018: IEEE Transactions on Biomedical Circuits and Systems
Aditya Parekh, Debanjan Das, Subhayan Das, Santanu Dhara, Karabi Biswas, Mahitosh Mandal, Soumen Das
Determination of cancer aggressiveness is mainly assessed in tissues by looking at the grade of cancer. There is a lack of specific method to determine aggressiveness of cancer cells in vitro. In our present work, we have proposed a bio-impedance based non-invasive method to differentiate aggressive property of two breast cancer cell lines. Real-time impedance analysis of MCF-7 (less aggressive) and MDA-MB-231 cells (more aggressive) demonstrated unique growth pattern. Detailed slope-analysis of impedance curves at different growth phases showed that MDA-MB-231 had higher proliferation rate and intrinsic resistance to cell death, when allowed to grow in nutrient and space limiting conditions...
January 15, 2018: Scientific Reports
N A Bylova, G P Arutyunov, A K Rylova, A S Simbirtseva, A G Arutyunov
AIM: To evaluate the effect of body composition on prediction of community-acquired pneumonia caused by Str. pneumoniae in patients with decompensated CHF. MATERIALS AND METHODS: The study included 216 patients. The pneumonia agent was identified by sputum culture. Body composition with determining lean body mass and fat mass was evaluated using a bio-impedance analysis; body mass index (BMI) was calculated. Patients with BMI 18.5-24.9 kg/m2 were included into the study...
2017: Kardiologiia
Haihua Xu, Ying Lv, Yongchun Deng, Qingqing Zhu
Interfacing an organic bulk heterojunction (OBHJ) with an aqueous electrolyte (aqE) solution has the potential for applications in biological sensing and neuronal stimulus, by taking advantage of the benefits of the high excitation efficiency and biocompatibility of the OBHJ. At the OBHJ/aqE interface, local charge transfer and transport processes, which are influenced by the polymer/fullerene interface and ion migration, are critically important for device performance but poorly understood. Here, we have introduced charge modulation spectroscopy (CMS) in aqE-gated heterojunction transistors to in situ investigate electronic dynamics at the OBHJ/aqE interface...
December 18, 2017: Physical Chemistry Chemical Physics: PCCP
Chan Soon Park, Sang-Eun Lee, Hyun-Jai Cho, Yong-Jin Kim, Hyun-Jae Kang, Byung-Hee Oh, Hae-Young Lee
Background/Aims: Fluid retention occurs in patients with heart failure, accounting for dyspnea. We investigated the diagnostic implication of body fluid status, assessed by bio-impedance analysis (BIA), in acute heart failure (AHF) among patients who presented with dyspnea. Methods: A total of 100 patients who presented with dyspnea and suspected with AHF were analyzed in this study. We enrolled 50 AHF and 50 non-AHF patients discriminated through echocardiographic analysis and Framingham criteria and were matched by age and sex...
December 18, 2017: Korean Journal of Internal Medicine
Nan Li, Egor M Larin, Kagan Kerman
Adrenocorticotropic hormone (ACTH) plays an essential role in regulating corticosteroid hormone production, which has important functions in a myriad of critical physiological functions. In this proof-of-concept study, a miniaturized immunosensor was developed for the highly sensitive detection of ACTH using electrochemical impedance spectroscopy (EIS) in connection with disposable screen-printed gold electrodes (SPGEs). A film of 3,3'-dithiobis[sulfosuccinimidylpropionate] (DTSSP) was prepared to immobilize anti-ACTH antibodies covalently on the nanostructured SPGE surface...
December 7, 2017: Sensors
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