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Global Health Research Ethics

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https://www.readbyqxmd.com/read/28931576/partnerships-for-global-child-health
#1
REVIEW
Andrew P Steenhoff, Heather L Crouse, Heather Lukolyo, Charles P Larson, Cynthia Howard, Loeto Mazhani, Suzinne Pak-Gorstein, Michelle L Niescierenko, Philippa Musoke, Roseda Marshall, Miguel A Soto, Sabrina M Butteris, Maneesh Batra
Child mortality remains a global health challenge and has resulted in demand for expanding the global child health (GCH) workforce over the last 3 decades. Institutional partnerships are the cornerstone of sustainable education, research, clinical service, and advocacy for GCH. When successful, partnerships can become self-sustaining and support development of much-needed training programs in resource-constrained settings. Conversely, poorly conceptualized, constructed, or maintained partnerships may inadvertently contribute to the deterioration of health systems...
September 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28871019/biopsychosocial-factors-associated-with-non-recovery-after-a-minor-transport-related-injury-protocol-for-a-systematic-review
#2
Stella Samoborec, Rasa Ruseckaite, Lorena Romero, Sue M Evans
INTRODUCTION: Globally, road transport accidents contribute substantially to the number of deaths and also to the burden of disability. Up to 50 million people suffer a transport-related non-fatal injury each year, which often leads to long-term disability. It has been shown that substantial number of people with minor injuries struggle to recover and the reasons are still not well explored.Despite the high prevalence, little is known about the factors hindering recovery following minor traffic-related injuries...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28864700/psychological-distress-and-quality-of-life-rationale-and-protocol-of-a-prospective-cohort-study-in-a-rural-district-in-bangaladesh
#3
Mohammed Nazim Uddin, Sunil Bhar, Abdullah Al Mahmud, Fakir M Amirul Islam
INTRODUCTION: A significant proportion of the global burden of disease has been attributed to mental and behavioural disorders. People with mental disorders (MDs) have lower levels of health-related quality of life than those without MDs. Several studies have shown that in low-resource countries, a range of social determinants including poor health literacy is critical in the epidemiological transition of disease outcome. There is a lack of evidence of MDs literacy, the prevalence and risk factors of common mental health conditions, or any validated instruments to measure psychological distress or evaluate the quality of life in rural areas of Bangladesh...
September 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28841897/developing-an-informational-tool-for-ethical-engagement-in-medical-tourism
#4
Krystyna Adams, Jeremy Snyder, Valorie A Crooks, Rory Johnston
BACKGROUND: Medical tourism, the practice of persons intentionally travelling across international boundaries to access medical care, has drawn increasing attention from researchers, particularly in relation to potential ethical concerns of this practice. Researchers have expressed concern for potential negative impacts to individual safety, public health within both countries of origin for medical tourists and destination countries, and global health equity. However, these ethical concerns are not discussed within the sources of information commonly provided to medical tourists, and as such, medical tourists may not be aware of these concerns when engaging in medical tourism...
August 25, 2017: Philosophy, Ethics, and Humanities in Medicine: PEHM
https://www.readbyqxmd.com/read/28832821/narrative-medicine-in-the-framework-of-empirical-social-research-the-russian-context
#5
Vitaly Lekhtsier, Anna Gotlib
This article contains the results of the empirical analysis carried out in 2012-2016 which sought to examine whether patients' narratives of their illness were present in doctor-patient communication and whether this subjective story was significant to both sides of the medical communication in Russian somatic disease medicine. The research was carried out in four stages and combined qualitative and quantitative methods, analyzing the perspectives of patients, doctors and medical students through surveys and interviews as well as looking at online doctor-patient communication in health forums...
April 2017: Salud Colectiva
https://www.readbyqxmd.com/read/28830078/reproducing-epidemiologic-research-and-ensuring-transparency
#6
Steven S Coughlin
Measures for ensuring that epidemiologic studies are reproducible include making data sets and software available to other researchers so they can verify published findings, conduct alternative analyses of the data, and check for statistical errors or programming errors. Recent developments related to the reproducibility and transparency of epidemiologic studies include the creation of a global platform for sharing data from clinical trials and the anticipated future extension of the global platform to non-clinical trial data...
August 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28828869/utilisation-of-the-partogram-among-nurses-and-midwives-in-selected-health-facilities-in-the-eastern-province-of-rwanda
#7
Oliva Bazirete, Nomafrench Mbombo, Oluyinka Adejumo
BACKGROUND: Maternal mortality continues to be a global burden, with more than 200 million women becoming pregnant each year and a large number dying as a result of complications of pregnancy or childbirth. The World Health Organisation has recommended use of the partogram to monitor labour and delivery in order to improve healthcare and reduce maternal and foetal mortality rates. OBJECTIVE: This study described factors affecting utilisation of the partogram among nurses and midwives in selected health facilities of Rwanda...
August 3, 2017: Curationis
https://www.readbyqxmd.com/read/28815982/bridge-the-gap-the-need-for-harmonized-regulatory-and-ethical-standards-for-postmarketing-observational-studies
#8
REVIEW
Hisashi Urushihara, Louise Parmenter, Shimon Tashiro, Kenji Matsui, Nancy Dreyer
Drug safety issues do not respect national borders. Hence, addressing a safety question may necessitate globally coordinated efforts between regulatory authorities and market authorization holders (MAHs) to draw reliable conclusions. Regulatory authorities have shared responsibility with MAHs sponsoring postmarketing nonintervention studies in determining study goals and design. Their shared accountabilities include what will be investigated and how the data will be retrieved to ensure appropriate study quality required for regulatory decision making...
August 16, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28809613/enrolling-hiv-positive-adolescents-in-mental-health-research-a-case-study-reflecting-on-legal-and-ethical-complexities
#9
Nataly Woollett, John Peter, Lucie Cluver, Heena Brahmbhatt
BACKGROUND: Adolescents living with HIV are an emerging group in the global HIV/AIDS epidemic. Mental health in this population affects HIV care, treatment, consequential morbidity and secondary transmission. There is a paucity of research regarding these youth in South Africa (SA), partly because section 71 of the National Health Act of 2003 (NHA) requires parental or guardian's consent. OBJECTIVE: To explore legal and ethical issues related to conducting adolescent mental health research in SA...
July 28, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28801396/the-sims-trial-adjustable-anchored-single-incision-mini-slings-versus-standard-tension-free-midurethral-slings-in-the-surgical-management-of-female-stress-urinary-incontinence-a-study-protocol-for-a-pragmatic-multicentre-non-inferiority-randomised-controlled
#10
Mohamed Abdel-Fattah, Graeme MacLennan, Mary Kilonzo, R Phil Assassa, Kirsty McCormick, Tracey Davidson, Alison McDonald, James N'Dow, Judith Wardle, John Norrie
INTRODUCTION: Single-incision mini-slings (SIMS) represent the third generation of midurethral slings. They have been developed with the aim of offering a true ambulatory procedure for treatment of female stress urinary incontinence (SUI) with reduced morbidity and earlier recovery while maintaining similar efficacy to standard midurethral slings (SMUS). The aim of this study is to determine the clinical and cost-effectiveness of adjustable anchored SIMS compared with tension-free SMUS in the surgical management of female SUI, with 3-year follow-up...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28780559/doctor-referral-of-overweight-people-to-a-low-energy-treatment-droplet-in-primary-care-using-total-diet-replacement-products-a-protocol-for-a-randomised-controlled-trial
#11
Susan A Jebb, Nerys M Astbury, Sarah Tearne, Alecia Nickless, Paul Aveyard
INTRODUCTION: The global prevalence of obesity has risen significantly in recent decades. There is a pressing need to identify effective interventions to treat established obesity that can be delivered at scale. The aim of the Doctor Referral of Overweight People to a Low-Energy Treatment (DROPLET) study is to determine the clinical effectiveness, feasibility and acceptability of referral to a low-energy total diet replacement programme compared with usual weight management interventions in primary care...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28775196/systematic-review-and-meta-analysis-of-infant-and-young-child-feeding-practices-enat-p-in-ethiopia-protocol
#12
Tesfa Dejenie Habtewold, Md Atiqul Islam, Nigussie Tadesse Sharew, Shimels Hussien Mohammed, Mulugeta Molla Birhanu, Balewgizie Sileshi Tegegne
INTRODUCTION: Infant and young child feeding (IYCF) is the cornerstone of infant and child survival, healthy growth and development, healthy future generations and national development. In spite of the importance of optimal nutrition in low- and middle-income countries, there has been no review conducted in Ethiopia. Thus, the aim of this systematic review and meta-analysis is to estimate the national coverage and identify the associated factors of IYCF practices in Ethiopia. METHODS: PubMed, Scopus, EMBASE, CINHAL, EBSCO, Web of Science and WHO Global Health Library databases will be searched for all available publications from 1 January 2000 to 30 September 2017...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28740618/ethical-issues-associated-with-medical-tourism-in-africa
#13
REVIEW
John J O Mogaka, Lucia Mupara, Joyce M Tsoka-Gwegweni
Global disparities in medical technologies, laws, economic inequities, and social-cultural differences drive medical tourism (MT), the practice of travelling to consume healthcare that is either too delayed, unavailable, unaffordable or legally proscribed at home. Africa is simultaneously a source and destination for MT. MT however, presents a new and challenging health ethics frontier, being largely unregulated and characterized by policy contradictions, minority discrimination and conflict of interest among role-players...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28729309/the-role-of-a-decision-support-smartphone-application-in-enhancing-community-health-volunteers-effectiveness-to-improve-maternal-and-newborn-outcomes-in-nairobi-kenya-quasi-experimental-research-protocol
#14
Pauline Bakibinga, Eva Kamande, Milka Omuya, Abdhalah K Ziraba, Catherine Kyobutungi
INTRODUCTION: Improving maternal and newborn survival remains major aspirations for many countries in the Global South. Slum settlements, a result of rapid urbanisation in many developing countries including Kenya, exhibit high levels of maternal and neonatal mortality. There are limited referral mechanisms for sick neonates and their mothers from the community to healthcare facilities with ability to provide adequate care. In this study, we specifically plan to develop and assess the added value of having community health volunteers (CHVs) use smartphones to identify and track mothers and children in a bid to reduce pregnancy-related complications and newborn deaths in the urban slums of Kamukunji subcounty in Nairobi, Kenya...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28727695/where-to-from-here-posthumous-healthcare-data-digital-e-lectronic-mortality-and-new-zealand-s-healthcare-future
#15
Katie Hoeksema, Richman Wee, Alastair Macdonald, Parry Guilford, Jesse Wall, Jon Cornwall
Ongoing improvements in digital data acquisition and storage has led to the phenomenon of e(lectronic)-mortality, where digital data can now exist for a potentially infinite period. Globally, many countries are facilitating the acquisition and researcher-led access to large-scale, population-based digitised healthcare data sets. Their utilisation has led to numerous positive advances in healthcare. New Zealand's medical record system is becoming increasingly digitised, and as a consequence there will be an ever-increasing resource of posthumous healthcare data stored digitally, including genomic information...
July 21, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28716796/clinical-and-cost-effectiveness-of-progressive-exercise-compared-with-best-practice-advice-with-or-without-corticosteroid-injection-for-the-treatment-of-rotator-cuff-disorders-protocol-for-a-2x2-factorial-randomised-controlled-trial-the-grasp-trial
#16
Sally Hopewell, David J Keene, Michael Maia Schl├╝ssel, Melina Dritsaki, Susan Dutton, Andrew Carr, William Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Hessam Soutakbar, Peter Heine, Lucy Cureton, Karen Barker, Sarah E Lamb
INTRODUCTION: Shoulder pain is very common, with around 70% of cases due to disorders of the rotator cuff. Despite widespread provision of physiotherapy, there is uncertainty about which type of exercise and delivery mechanisms are associated with best outcomes. There is also uncertainty around the long-term benefits and harms of corticosteroid injection therapy, which is often used in addition to physiotherapy. The Getting it Right: Addressing Shoulder Pain trial will assess the clinical and cost-effectiveness of individually tailored, progressive exercise compared with best practice advice, with or without corticosteroid injection, in adults with a rotator cuff disorder...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28706087/periconception-endogenous-and-exogenous-maternal-sex-steroid-hormones-and-risk-of-asthma-and-allergy-in-offspring-protocol-for-a-systematic-review-and-meta-analysis
#17
Merhunisa Talovic, Aziz Sheikh, Nicola McCleary, Maijaliisa Erkkola, Minna Kaila, Suvi M Virtanen, Bright I Nwaru
INTRODUCTION: Pregnancy is associated with several hormonal changes which influence the developing fetus. Variations in maternal endogenous hormones and prepregnancy use of hormonal preparations have been linked to asthma and allergy in the offspring, but findings are inconsistent. We plan to undertake a systematic review to synthesise the evidence on the association between endogenous and exogenous maternal sex hormones and the risk of asthma and allergy in the offspring. METHODS AND ANALYSIS: We will search Medline, Embase, Cochrane Library, Institute of Scientific Information Web of Science, Cumulative Index of Nursing and Allied Health, Scopus, Google Scholar, Allied and Complementary Medicine Database, Global Health, Psychological Information (PsycINFO), Centre for Agriculture and Bioscience (CAB) International and WHO Global Health Library from inception until 2016 to identify relevant studies on the topic...
July 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28690734/individual-and-socioeconomic-factors-associated-with-childhood-immunization-coverage-in-nigeria
#18
Obinna Oleribe, Vibha Kumar, Adebowale Awosika-Olumo, Simon David Taylor-Robinson
INTRODUCTION: Immunization is the world's most successful and cost-effective public health intervention as it prevents over 2 million deaths annually. However, over 2 million deaths still occur yearly from Vaccine preventable diseases, the majority of which occur in sub-Saharan Africa. Nigeria is a major contributor of global childhood deaths from VPDs. Till date, Nigeria still has wild polio virus in circulation. The objective of this study was to identify the individual and socioeconomic factors associated with immunization coverage in Nigeria through a secondary dataset analysis of Nigeria Demographic and Health Survey (NDHS), 2013...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28687532/studying-scale-up-and-spread-as-social-practice-theoretical-introduction-and-empirical-case-study
#19
James Shaw, Sara Shaw, Joseph Wherton, Gemma Hughes, Trisha Greenhalgh
BACKGROUND: Health and care technologies often succeed on a small scale but fail to achieve widespread use (scale-up) or become routine practice in other settings (spread). One reason for this is under-theorization of the process of scale-up and spread, for which a potentially fruitful theoretical approach is to consider the adoption and use of technologies as social practices. OBJECTIVE: This study aimed to use an in-depth case study of assisted living to explore the feasibility and usefulness of a social practice approach to explaining the scale-up of an assisted-living technology across a local system of health and social care...
July 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28674137/key-priority-areas-for-patient-safety-improvement-strategy-in-libya-a-protocol-for-a-modified-delphi-study
#20
Mustafa Elmontsri, Ricky Banarsee, Azeem Majeed
INTRODUCTION: Patient safety is a global public health problem. Estimates and size of the problem of patient safety in low-income and developing countries are scarce. A systems approach is needed for ensuring that patients are protected from harm while receiving care. The primary objective of this study will be to use a consensus-based approach to identify the key priority areas for patient safety improvement in Libya as a developing country. DESIGN: A modified Delphi study...
July 2, 2017: BMJ Open
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