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https://www.readbyqxmd.com/read/28916260/primary-facial-reanimation-in-head-and-neck-cancer
#1
REVIEW
Axel Sahovaler, David Yeh, John Yoo
Facial Paralysis (FP) profoundly impairs the life of individuals, both functionally and psychosocially. Surgical approaches to treat this condition are myriad, but the ultimate goal is to restore symmetry and movement. Ablative surgery for tumors of the head and neck region are amongst the most common etiologies causing FP and this group of patients represents unique challenges. Surgical defects may have multiple competing reconstructive requirements and addressing the FP must be considered in this context...
September 12, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28891433/innate-lymphoid-cells-mediate-pulmonary-eosinophilic-inflammation-airway-mucous-cell-metaplasia-and-type-2-immunity-in-mice-exposed-to-ozone
#2
Kazuyoshi Kumagai, Ryan P Lewandowski, Daven N Jackson-Humbles, Nicholas Buglak, Ning Li, Kaylin White, Steven J Van Dyken, James G Wagner, Jack R Harkema
Exposure to elevated levels of ambient ozone in photochemical smog is associated with eosinophilic airway inflammation and nonatopic asthma in children. In the present study, we determined the role of innate lymphoid cells (ILCs) in the pathogenesis of ozone-induced nonatopic asthma by using lymphoid cell-sufficient C57BL/6 mice, ILC-sufficient Rag2(-/-) mice (devoid of T and B cells), and ILC-deficient Rag2(-/-)Il2rg(-/-) mice (depleted of all lymphoid cells including ILCs). Mice were exposed to 0 or 0.8 parts per million ozone for 1 day or 9 consecutive weekdays (4 hr/day)...
January 1, 2017: Toxicologic Pathology
https://www.readbyqxmd.com/read/28882797/modification-of-the-plasma-complement-protein-profile-by-exogenous-estrogens-is-indicative-of-a-compromised-immune-competence-in-marine-medaka-oryzias-melastigma
#3
Miao Dong, Frauke Seemann, Joseph L Humble, Yimin Liang, Drew R Peterson, Rui Ye, Honglin Ren, Hui-Su Kim, Jae-Seong Lee, Doris W T Au, Yun Wah Lam
Growing evidence suggests that the immune system of teleost is vulnerable to xenoestrogens, which are ubiquitous in the marine environment. This study detected and identified the major circulatory immune proteins deregulated by 17α-ethinylestradiol (EE2), which may be linked to fish susceptibility to pathogens in the marine medaka, Oryzias melastigma. Fish immune competence was determined using a host resistance assay to pathogenic bacteria Edwardsiella tarda. Females were consistently more susceptible to infection-induced mortality than males...
September 4, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28857578/awe-and-humility
#4
Jennifer E Stellar, Amie Gordon, Craig L Anderson, Paul K Piff, Galen D McNeil, Dacher Keltner
Humility is a foundational virtue that counters selfish inclinations such as entitlement, arrogance, and narcissism (Tangney, 2000). We hypothesize that experiences of awe promote greater humility. Guided by an appraisal-tendency framework of emotion, we propose that when individuals encounter an entity that is vast and challenges their worldview, they feel awe, which leads to self-diminishment and subsequently humility. In support of these claims, awe-prone individuals were rated as more humble by friends (Study 1) and reported greater humility across a 2-week period (Study 2), controlling for other positive emotions...
August 31, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28847119/in-reply-to-small-stories-in-defense-of-the-humble-case-report
#5
LETTER
Hussam Abou-Al-Shaar, Abdulrahman J Sabbagh
No abstract text is available yet for this article.
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28847118/small-stories-in-defense-of-the-humble-case-report
#6
LETTER
Christopher S Graffeo, Avital Perry, Lucas P Carlstrom, William R Copeland, Kathryn M Van Abel, Michael J Link
No abstract text is available yet for this article.
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28831545/how-the-humble-insect-brain-became-a-powerful-experimental-model-system
#7
REVIEW
Heinrich Reichert
In the 21st century, neurobiological studies focused on the insect brain are revealing unprecedented insight into the molecular, cellular, developmental, and circuit aspects of brain organization and function, notably in the genetic model system of Drosophila melanogaster. Underlying this accelerating progress in understanding the insect brain is a century-long history of ground breaking experimental investigation, methodological advance, and conceptual insight catalyzed by the integration of two emerging research fields, neuroscience and genetics...
August 22, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28829441/nk-cells-join-the-plasticity-party
#8
Jonathan S Silver, Alison A Humbles
No abstract text is available yet for this article.
August 22, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28792579/-a-new-challenge-of-working-together-psychiatry-and-heraing-voices
#9
Christian Laval
Recovery model, as the hearing voices movement, promotes the users discourse among the health workers. This interference of users in the expertise considering the meaning of their voices is faced with the vision of advocating health workers, particularly the psychiatrists supporting the psychiatric users movement. On the field, this association seems challenging. On the experimental site in Marseille, professionals through various tensions and practical difficulties tend to reconsider their power / knowledge...
2017: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/28782216/temporal-changes-in-neutropenic-blood-culture-isolates-and-disease-associations-a-single-centre-series-of-1139-episodes
#10
Nathanael Lucas, Michael Humble, Dalice Sim, Michelle Balm, John Carter, Robert Weinkove
Neutropenic infections are life-threatening and require empiric antibiotic treatment. We examined 1139 blood culture isolates from our institution over a 36-year period from neutropenic patients to examine temporal trends and disease associations. Positive associations were found between viridans streptococci and acute myeloid leukaemia, coagulase negative staphylococci and acute lymphoblastic leukaemia and Pseudomonas aeruginosa and indolent B-cell malignancies.
August 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28764950/prognosis-after-cardiac-arrest-vindication-of-the-humble-ct-scan
#11
EDITORIAL
G Bryan Young
No abstract text is available yet for this article.
July 29, 2017: Resuscitation
https://www.readbyqxmd.com/read/28755564/measurements-of-argon-39-at-the-u20az-underground-nuclear-explosion-site
#12
J I McIntyre, C E Aalseth, T R Alexander, H O Back, B J Bellgraph, T W Bowyer, V Chipman, M W Cooper, A R Day, S Drellack, M P Foxe, B G Fritz, J C Hayes, P Humble, M E Keillor, R R Kirkham, E J Krogstad, J D Lowrey, E K Mace, M F Mayer, B D Milbrath, A Misner, S M Morley, M E Panisko, K B Olsen, M D Ripplinger, A Seifert, R Suarez
Pacific Northwest National Laboratory reports on the detection of (39)Ar at the location of an underground nuclear explosion on the Nevada Nuclear Security Site. The presence of (39)Ar was not anticipated at the outset of the experimental campaign but results from this work demonstrated that it is present, along with (37)Ar and (85)Kr in the subsurface at the site of an underground nuclear explosion. Our analysis showed that by using state-of-the-art technology optimized for radioargon measurements, it was difficult to distinguish (39)Ar from the fission product (85)Kr...
July 26, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28746485/an-interview-with-steven-j-lindauer
#13
Steven J Lindauer
There are so many compliments to Dr. Steven Lindauer that is hard for one to figure where to start from… Well, travelling backwards in time, all the way to the year 2000, I went to Virginia to study English at Virginia Commonwealth University (VCU), in Richmond, Virginia, USA. During my daily walks to the English school, I used to pass by the School of Dentistry, where the Department of Orthodontics was. That was the place where my very first "contact" with the VCU happened. In 2015, 15 years later, I had the pleasure to go back to the VCU and spend two days with Dr...
May 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28710948/brainstem-auditory-evoked-potentials-for-diagnosing-autism-spectrum-disorder-adhd-and-schizophrenia-spectrum-disorders-in-adults-a-blinded-study
#14
Irina Manouilenko, Mats B Humble, Jeanette Georgieva, Susanne Bejerot
The aim of the present study was to examine the clinical utility of complex auditory brainstem response (c-ABR) and investigate if c-ABR is helpful in the diagnostic procedure. Thirty-one adult psychiatric patients, thoroughly diagnosed with autism spectrum disorder (ASD) (n=16), ADHD (n=8), or schizophrenia spectrum disorder (SSD) (n=7) and 15 healthy controls (HC), were blindly assessed with SensoDetect BERA. This c-ABR correctly identified psychiatric diagnoses in 4 patients (13%) and provided partially correct diagnoses in 11 more patients...
July 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28704444/maternal-inheritance-of-deltamethrin-resistance-in-the-salmon-louse-lepeophtheirus-salmonis-kr%C3%A3-yer-is-associated-with-unique-mtdna-haplotypes
#15
Greta Carmona-Antoñanzas, Michaël Bekaert, Joseph L Humble, Sally Boyd, William Roy, David I Bassett, Ross D Houston, Karim Gharbi, James E Bron, Armin Sturm
Parasitic infections by the salmon louse, Lepeophtheirus salmonis (Krøyer), cause huge economic damage in salmon farming in the northern hemisphere, with combined treatment costs and production losses in 2014 having been estimated at US$ 350 million for Norway (annual production 1.25 million tonnes). The control of L. salmonis relies significantly on medicinal treatments, supplemented by non-pharmacological approaches. However, efficacy losses have been reported for several delousing agents, including the pyrethroid deltamethrin...
2017: PloS One
https://www.readbyqxmd.com/read/28681125/a-cross-sectional-review-of-patient-information-available-in-the-world-wide-web-on-cyberknife-fallacies-and-pitfalls
#16
Durgapoorna Menon, Prameela G Chelakkot, Devika Sunil, Ashwini Lakshmaiah
PURPOSE: The purpose of this study is to assess the quality of videos available in YouTube on CyberKnife. METHODS: The term "CyberKnife" was input into the search window of www.youtube.com on a specific date and the first 50 videos were assessed for technical and content issues. The data was tabulated and analysed. RESULTS: The search yielded 32,300 videos in 0.33 s. Among the first 50 analysed, most were professional videos, mostly on CyberKnife in general and for brain tumours...
July 5, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28662064/identifiers-for-the-21st-century-how-to-design-provision-and-reuse-persistent-identifiers-to-maximize-utility-and-impact-of-life-science-data
#17
Julie A McMurry, Nick Juty, Niklas Blomberg, Tony Burdett, Tom Conlin, Nathalie Conte, Mélanie Courtot, John Deck, Michel Dumontier, Donal K Fellows, Alejandra Gonzalez-Beltran, Philipp Gormanns, Jeffrey Grethe, Janna Hastings, Jean-Karim Hériché, Henning Hermjakob, Jon C Ison, Rafael C Jimenez, Simon Jupp, John Kunze, Camille Laibe, Nicolas Le Novère, James Malone, Maria Jesus Martin, Johanna R McEntyre, Chris Morris, Juha Muilu, Wolfgang Müller, Philippe Rocca-Serra, Susanna-Assunta Sansone, Murat Sariyar, Jacky L Snoep, Stian Soiland-Reyes, Natalie J Stanford, Neil Swainston, Nicole Washington, Alan R Williams, Sarala M Wimalaratne, Lilly M Winfree, Katherine Wolstencroft, Carole Goble, Christopher J Mungall, Melissa A Haendel, Helen Parkinson
In many disciplines, data are highly decentralized across thousands of online databases (repositories, registries, and knowledgebases). Wringing value from such databases depends on the discipline of data science and on the humble bricks and mortar that make integration possible; identifiers are a core component of this integration infrastructure. Drawing on our experience and on work by other groups, we outline 10 lessons we have learned about the identifier qualities and best practices that facilitate large-scale data integration...
June 2017: PLoS Biology
https://www.readbyqxmd.com/read/28629982/polymeric-nanoparticles-promising-platform-for-drug-delivery
#18
REVIEW
Khalid M El-Say, Hossam S El-Sawy
Nano medicine had viewed countless breakthroughs in drug delivery implementations. The main objective of nanotechnology application in delivering and carrying many promising therapeutics is to assure drugs carriage to their action sites, to maximize the pharmacological desired influence of remedies and to overcome their limitations and drawbacks that would hinder the required effectiveness. One of these applications was the particulates type of nano-range in size and tremendous impact in achievement. About this specific diversity of particulates, the different elaboration methodologies, mandatory and elementary components for design, and examples of splendid success stories for these particulates were emphasized in this humble review...
August 7, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28615200/kallikrein-related-peptidase-5-contributes-to-h3n2-influenza-virus-infection-in-human-lungs
#19
Mélia Magnen, Fabien Gueugnon, Antoine Guillon, Thomas Baranek, Virginie C Thibault, Agnès Petit-Courty, Simon J de Veer, Jonathan Harris, Alison A Humbles, Mustapha Si-Tahar, Yves Courty
Hemagglutinin (HA) of influenza virus must be activated by proteolysis before the virus can become infectious. Previous studies indicated that HA cleavage is driven by membrane-bound or extracellular serine proteases in the respiratory tract. However, there is still uncertainty as to which proteases are critical for activating HAs of seasonal influenza A viruses (IAVs) in humans. This study focuses on human KLK1 and KLK5, 2 of the 15 serine proteases known as the kallikrein-related peptidases (KLKs). We find that their mRNA expression in primary human bronchial cells is stimulated by IAV infection...
August 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28579868/evidence-based-brief-obsessive-compulsive-scale
#20
COMMENT
Susanne Bejerot, Gunnar Edman, Louise Frisén, Mats Humble
No abstract text is available yet for this article.
2017: Journal of Central Nervous System Disease
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