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Magnetic resonance enterography

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https://www.readbyqxmd.com/read/29737955/comparison-of-two-neutral-oral-contrast-agents-in-pediatric-patients-a-prospective-randomized-study
#1
Jonathan R Dillman, Alexander J Towbin, Rebecca Imbus, Julie Young, Erica Gates, Andrew T Trout
Purpose To prospectively compare small bowel distention provided by, as well as patient acceptance of, two different neutral (negative) oral contrast materials used for cross-sectional enterography in a pediatric population. Materials and Methods In this noninferiority study, 66 pediatric patients undergoing clinical computed tomographic (CT) or magnetic resonance (MR) enterography were randomized to receive either a flavored beverage for neutral abdominal and pelvic imaging (Breeza; Beekley Medical, Bristol, Conn) or a low-density barium sulfate suspension...
May 8, 2018: Radiology
https://www.readbyqxmd.com/read/29705029/usefulness-of-contrast-enhanced-ultrasound-ceus-in-inflammatory-bowel-disease-ibd
#2
REVIEW
Silvia Pecere, Grainne Holleran, Maria Elena Ainora, Matteo Garkovic, Franco Scaldaferri, Antonio Gasbarrini, Maria Assunta Zocco
Intestinal ultrasonography has emerged as a cheap, non-invasive and readily accessible modality for the assessment of a number of gastroenterological diseases. Over the last decade, particularly due to the widespread use of biological agents in Inflammatory Bowel Disease (IBD), guidelines regarding management and follow-up advise more regular disease assessment and surveillance in order to guide treatment adjustments, and provide more personalised care. Given the young age of the majority of patients with IBD the availability of an alternative modality to harmful radiation or the risks of endoscopy for this indication offers an appealing advantage...
April 3, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29696432/mesenteric-lymph-nodes-in-mr-enterography-are-they-reliable-followers-of-bowel-in-active-crohn-s-disease
#3
Amir Reza Radmard, Rana Eftekhar Vaghefi, Seyed Ali Montazeri, Sara Naybandi Atashi, Amir Pejman Hashemi Taheri, Sepehr Haghighi, Aneseh Salehnia, Mehrdad Dadgostar, Reza Malekzadeh
OBJECTIVES: To demonstrate magnetic resonance enterography (MRE) features of mesenteric lymph nodes (LN) in patients with Crohn's disease (CD) and investigate whether they follow enhancement or apparent diffusion coefficient (ADC) parameters of bowel. METHODS: This study was approved by the institutional review board. A total of 788 MREs from patients with CD were retrospectively reviewed. Eighty-eight patients, aged 16-66 years, including 59 active cases, were enrolled based on inclusion criteria...
April 25, 2018: European Radiology
https://www.readbyqxmd.com/read/29686731/a-review-of-magnetic-resonance-enterography-based-indices-for-quantification-of-crohn-s-disease-inflammation
#4
REVIEW
Noa Rozendorn, Marianne Michal Amitai, Rami Abraham Eliakim, Uri Kopylov, Eyal Klang
Magnetic resonance enterography (MRE) is a leading radiological modality in Crohn's disease (CD) and is used together with laboratory findings and endoscopic examinations for the evaluation of patients during initial diagnosis and follow up. Over the years, there has been great progress in the understanding of CD and there is a continuous strive to achieve better monitoring of patients and to develop new modalities which will predict disease course and thus help in clinical decisions making. An objective evaluation of CD using a quantification score is not a new concept and there are different clinical, endoscopies, radiological and combined indices which are used in clinical practice...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29685526/paediatric-magnetic-resonance-enterography-in-inflammatory-bowel-disease
#5
Mary-Louise C Greer
Paediatric magnetic resonance enterography (MRE) has been increasingly employed in the evaluation of inflammatory bowel disease (IBD) in the past decade. This is in parallel with a global rise in paediatric-onset IBD, greater recognition of the hazards of ionizing radiation, especially in children, and improved treatment options. MRE is now the reference standard for assessing the small bowel in suspected or proven paediatric IBD, and is central to the diagnosis of Crohn's disease (CD), helping distinguish it from ulcerative colitis...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29668921/predictors-of-durability-of-radiological-response-in-patients-with-small-bowel-crohn-s-disease
#6
Parakkal Deepak, Joel G Fletcher, Jeff L Fidler, John M Barlow, Shannon P Sheedy, Amy B Kolbe, William S Harmsen, Terry Therneau, Stephanie L Hansel, Brenda D Becker, Edward V Loftus, David H Bruining
Background: The long-term significance of radiological transmural response (TR) as a treatment goal at the first follow-up scan in small bowel Crohn's disease (CD) has been previously shown. We examined the durability of a long-term strategy of treating to a target of radiological TR and the influence of baseline predictors on the maintenance of TR. Methods: Small bowel CD patients between January 1, 2002, and December 31, 2014, were identified with serial computed tomography enterography (CTE)/magnetic resonance enterography (MRE) before and after initiation of therapy or on maintenance therapy...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29662538/the-accuracy-of-intestinal-ultrasound-compared-with-small-bowel-capsule-endoscopy-in-assessment-of-suspected-crohn-s-disease-in-patients-with-negative-ileocolonoscopy
#7
Dan Carter, Lior H Katz, Eytan Bardan, Eti Salomon, Shulamit Goldstein, Shomron Ben Horin, Uri Kopylov, Rami Eliakim
Background: Small bowel involvement in Crohn's disease (CD) is frequently proximal to the ileocecal valve and inaccessible by conventional ileocolonoscopy (IC). Small bowel capsule endoscopy (SBCE) is among the prime modalities for assessment of small bowel disease in these patients. Intestinal ultrasound (IUS) is an accurate bedside fast and low-cost diagnostic modality utilized in CD for both diagnosis and monitoring. The aim of this study was to examine the accuracy of IUS in patients with suspected CD after a negative IC, and to evaluate the correlation of IUS with SBCE, inflammatory biomarkers and other cross-sectional imaging techniques...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29651607/detecting-inflammation-in-inflammatory-bowel-disease-how-does-ultrasound-compare-to-magnetic-resonance-enterography-using-standardised-scoring-systems
#8
Joy L Barber, Alexsandra Zambrano-Perez, Øystein E Olsen, Fevronia Kiparissi, Mila Baycheva, Daniela Knaflez, Neil Shah, Tom A Watson
BACKGROUND: Magnetic resonance enterography (MRE) is the current gold standard for imaging in inflammatory bowel disease, but ultrasound (US) is a potential alternative. OBJECTIVE: To determine whether US is as good as MRE for the detecting inflamed bowel, using a combined consensus score as the reference standard. MATERIALS AND METHODS: We conducted a retrospective cohort study in children and adolescents <18 years with inflammatory bowel disease (IBD) at a tertiary and quaternary centre...
April 13, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29643328/superior-mesenteric-artery-syndrome-in-patients-with-crohn-s-disease-a-description-of-2-cases-studied-with-a-novel-magnetic-resonance-enterography-mre-procedure
#9
Giuseppe Cicero, Tommaso D'Angelo, Antonio Bottari, Giuseppe Costantino, Carmela Visalli, Sergio Racchiusa, Maria Adele Marino, Marco Cavallaro, Luciano Frosina, Alfredo Blandino, Silvio Mazziotti
BACKGROUND Superior mesenteric artery syndrome is caused by vascular compression of the third portion of the duodenum between the aorta and the superior mesenteric artery. It may occur with acute or chronic symptomatology, such as vomiting or postprandial abdominal pain, and it is usually caused by a lack of mesenteric fat pad under conditions of severe weight loss. Crohn's disease can be one of them. CASE REPORT We report 2 cases of Crohn's disease patients with clinical suspicion of jejunal stricture who underwent MR-enterography with a novel approach...
April 12, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29611841/significance-of-diffusion-weighted-imaging-dwi-as-an-improving-factor-in-contrast-enhanced-magnetic-resonance-imaging-mri-enterography-in-evaluation-of-patients-with-crohn-s-disease
#10
Bilal Imširović, Enver Zerem, Alma Efendić, Alma Mekić Abazović, Omar Zerem, Muhamed Djedović
Aim To determine capabilities and potential of contrast enhanced magnetic resonance imaging (MRI) enterography in order to establish the diagnosis and to evaluate severity and activity of intestinal inflammation. Methods Fifty-five patients with suspicion for presence of Crohn's disease were evaluated. All patients underwent contrast enhanced MRI enterography and diffusion weighted imaging (DWI), and subsequently endoscopic examination or surgical treatment. Four parameters were analysed: thickening of the bowel wall, and presence of abscess, fistula and lymphadenopathy...
August 1, 2018: Medicinski Glasnik
https://www.readbyqxmd.com/read/29549474/contributions-of-magnetic-resonance-imaging-to-gastroenterological-practice-mris-for-gis
#11
REVIEW
Christopher G Roth, Dina Halegoua-De Marzio, Flavius F Guglielmo
MRI has transformed from the theoretical, investigative realm to mainstream clinical medicine over the past four decades and has become a core component of the diagnostic toolbox in the practice of gastroenterology (GI). Its success is attributable to exquisite contrast and the ability to isolate specific proton species through the use of different pulse sequences (i.e., T1-weighted, T2-weighted, diffusion-weighted) and exploiting extracellular and hepatobiliary contrast agents. Consequently, MRI has gained preeminence in various GI clinical applications: liver and pancreatic lesion evaluation and detection, liver transplantation evaluation, pancreatitis evaluation, Crohn's disease evaluation (using MR enterography) rectal cancer staging and perianal fistula evaluation...
March 16, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29506048/comparison-of-capsule-endoscopy-and-magnetic-resonance-enterography-for-the-assessment-of-small-bowel-lesions-in-crohn-s-disease
#12
Begoña González-Suárez, Sonia Rodriguez, Elena Ricart, Ingrid Ordás, Jordi Rimola, Álvaro Díaz-González, Cristina Romero, Cristina Rodríguez de Miguel, Arantxa Jáuregui, Isis K Araujo, Anna Ramirez, Marta Gallego, Gloria Fernández-Esparrach, Ángels Ginés, Oriol Sendino, Josep Llach, Julian Panés
Background and Aims: Diagnostic yield of Small Bowel Capsule Endoscopy (SBCE) for the assessment of small bowel (SB) lesions is higher than radiologic imaging techniques. However, magnetic resonance enterography (MRE) data are scarce and inconclusive. Colon Capsule Endoscopy (CCE) is a new capsule modality. The primary aim of our study was to compare MRE and capsule endoscopy (CE) for the assessment of Crohn's disease (CD). The secondary objectives were to compare the diagnostic accuracy of both CE modalities and changes in Montreal classification after each examination...
March 19, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29501599/associations-among-mucosal-and-transmural-healing-and-fecal-level-of-calprotectin-in-children-with-crohn-s-disease
#13
Inbar Nakar, Gili Focht, Peter Church, Thomas D Walters, Guila Abitbol, Sudha Anupindi, Laureline Berteloot, Jessie M Hulst, Frank Ruemmele, Daniel A Lemberg, Steven T Leach, Ruth Cytter, Mary-Louise Greer, Anne M Griffiths, Dan Turner
BACKGROUND & AIMS: Bowel healing is an important goal of therapy for patients with Crohn's disease (CD). Although there have been many studies of mucosal healing, transmural healing (in the bowel wall) has not been investigated in children. We analyzed data from the ImageKids study to determine associations among mucosal and transmural healing and levels of calprotectin and C-reactive protein in children with CD. METHODS: We collected data from a multi-center study designed to develop 2 magnetic resonance enterography (MRE)-based measures for children with CD (6-18 years old)...
March 2, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29500613/-radiological-characterization-of-chronic-inflammatory-bowel-disease
#14
REVIEW
H Schöllnast
BACKGROUND: During the course of the disease, chronic inflammatory bowel diseases (CIBD) show different activities, which-in addition to morphological changes-significantly influence the choice of therapy. OBJECTIVE: The value of imaging in characterization of the activity of inflammatory changes is evaluated. MATERIALS AND METHODS: In the present review of the current literature, indications, performance, and findings of imaging of inflammatory bowel disease and on the assessment of disease activity are assessed...
April 2018: Der Radiologe
https://www.readbyqxmd.com/read/29499912/quantitative-bowel-apparent-diffusion-coefficient-measurements-in-children-with-inflammatory-bowel-disease-are-not-reproducible
#15
T Watson, A Calder, J L Barber
AIM: To investigate the intra-observer and interobserver variability of quantitative apparent diffusion coefficient (ADC) measurements in children with inflammatory bowel disease. MATERIALS AND METHODS: Nine readers were recruited. Six magnetic resonance imaging (MRI) enterography cases with known active disease in the jejunum, terminal ileum, or colon were analysed. Readers measured repeat ADC values from the known diseased site and an unaffected site, at two sittings...
June 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29455313/-18-f-fdg-pet-mr-enterography-for-the-assessment-of-inflammatory-activity-in-crohn-s-disease-comparison-of-different-mri-and-pet-parameters
#16
Yan Li, Karsten Beiderwellen, Felix Nensa, Johannes Grüneisen, Gustav Dobos, Ken Herrmann, Thomas Lauenstein, Lale Umutlu, Jost Langhorst
PURPOSE: To evaluate the diagnostic performance of integrated whole-body positron emission tomography (PET)/magnetic resonance (MR) enterography in patients with Crohn's disease (CD). METHODS: Fifty patients with known CD and recurrent symptoms underwent ileocolonoscopy (reference standard) as well as PET/MR enterography. Seven ileocolonic segments were endoscopically analysed using the Simplified Endoscopic Activity Score for Crohn's Disease (SES-CD) and additionally classified into three categories of inflammation (none, mild to moderate and severe ulcerative inflammation)...
February 17, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29438853/gastric-ulceration-and-perforation-secondary-to-large-trichobezoar-a-case-report-describing-the-role-of-magnetic-resonance-imaging-in-diagnosis
#17
M M Hennessy, I Ivanovski, C B Ó Súilleabháin
INTRODUCTION: Trichotillomania and trichotillophagia can result in huge intraluminal coagulations of hair. Rarely, these can present with gastric perforation. This work has been reported in line with the SCARE criteria (Agha et al., 2016) [1]. PRESENTATION OF CASE: We report the case of a 15 year old girl who attended the emergency department with abdominal pain and vomiting. Ultrasound abdomen and pelvis identified free fluid within the pelvis concerning for inflammatory bowel disease...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29428210/semiautomatic-assessment-of-the-terminal-ileum-and-colon-in-patients-with-crohn-disease-using-mri-the-vigor-project
#18
Carl A J Puylaert, Peter J Schüffler, Robiel E Naziroglu, Jeroen A W Tielbeek, Zhang Li, Jesica C Makanyanga, Charlotte J Tutein Nolthenius, C Yung Nio, Douglas A Pendsé, Alex Menys, Cyriel Y Ponsioen, David Atkinson, Alastair Forbes, Joachim M Buhmann, Thomas J Fuchs, Haralambos Hatzakis, Lucas J van Vliet, Jaap Stoker, Stuart A Taylor, Frans M Vos
RATIONALE AND OBJECTIVES: The objective of this study was to develop and validate a predictive magnetic resonance imaging (MRI) activity score for ileocolonic Crohn disease activity based on both subjective and semiautomatic MRI features. MATERIALS AND METHODS: An MRI activity score (the "virtual gastrointestinal tract [VIGOR]" score) was developed from 27 validated magnetic resonance enterography datasets, including subjective radiologist observation of mural T2 signal and semiautomatic measurements of bowel wall thickness, excess volume, and dynamic contrast enhancement (initial slope of increase)...
February 7, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29361096/reliability-of-measuring-ileo-colonic-disease-activity-in-crohn-s-disease-by-magnetic-resonance-enterography
#19
Vipul Jairath, Ingrid Ordas, Guangyong Zou, Julian Panes, Jaap Stoker, Stuart A Taylor, Cynthia Santillan, Karin Horsthuis, Mark A Samaan, Lisa M Shackelton, Larry W Stitt, Pieter Hindryckx, Reena Khanna, William J Sandborn, Geert D'Haens, Brian G Feagan, Barrett G Levesque, Jordi Rimola
Background: Magnetic resonance enterography is increasingly utilized for assessment of luminal Crohn's disease activity. The Magnetic Resonance Index of Activity and the London Index are the most commonly used outcome measures in clinical trials. We assessed the reliability of these indices and several additional items. Methods: A consensus process clarified scoring conventions and identified additional items based on face validity. Four experienced radiologists evaluated 50 images in triplicate, in random order, at least 1 month apart, using a central image management system...
January 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29342997/-x-linked-inhibitor-of-apoptosis-deficiency-manifested-as-crohn-s-disease-a-case-report-and-literature-review
#20
L J Xu, Y Y Luo, J D Yu, J G Lou, Y H Fang, J Chen
Objective: To analyze the clinical characteristics of X-linked inhibitor of apoptosis (XIAP) deficient patients with clinical manifestation of Crohn's disease. Methods: Clinical manifestations, laboratory investigations, genetic testing and therapeutic interventions of one case of XIAP deficiency who was admitted to Department of Gastroenterology in Children's Hospital, Zhejiang University School of Medicine in May 2016 were summarized. PubMed and Chinese database for articles published from January 2016 to June 2017 were searched using the key words of'Crohn's disease'and'XIAP', and the relevant literature was reviewed...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
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