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Magnetic resonance enterography

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https://www.readbyqxmd.com/read/28630777/magnetic-resonance-enterography-findings-of-intestinal-beh%C3%A3-et-disease-in-a-child
#1
Tommaso D'Angelo, Romina Gallizzi, Claudio Romano, Giuseppe Cicero, Silvio Mazziotti
Behçet's disease (BD) is a multisystem disorder of unknown aetiology, characterized by recurrent oral ulcers, genital ulcers, uveitis, skin lesions, and pathergy. Gastrointestinal disease outside the oral cavity is well recognized and usually takes the form of small intestinal ulcers, with the most significant lesions frequently occurring in the ileocaecal region. Symptoms usually include nausea, vomiting, colicky abdominal pain, and change in bowel habit and it is not unusual that patients may present late, with life-threatening complications requiring surgery...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28612164/increasing-efficiency-of-mre-for-diagnosis-of-crohn-s-disease-activity-through-proper-sequence-selection-a-practical-approach-for-clinical-trials
#2
Jordi Rimola, Almudena Alvarez-Cofiño, Tamara Pérez-Jeldres, Sonia Rodríguez, Ignacio Alfaro, Ingrid Ordás, Elena Ricart, Julián Panés
PURPOSE: To derive the best magnetic resonance enterography (MRE) approach for detecting activity and severe lesions in Crohn's disease (CD) to use for selecting patients and measuring response to treatment in clinical trials. METHODS: We compared the accuracies of MRE (T2-weighted sequences, DWI (b = 800 s/mm(2)) sequences, combined T2-weighted and DWI sequences, combined T2-weighted or DWI sequences, and MaRIA score based on T2-weighted and contrast-enhanced T1-weighted sequences) versus ileocolonoscopy (SES-CD) performed within 1 month...
June 13, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28595876/a-diagnostic-accuracy-meta-analysis-of-ct-and-mri-for-the-evaluation-of-small-bowel-crohn-disease
#3
Wenhong Liu, Jincai Liu, Wenlian Xiao, Guanghua Luo
RATIONALE AND OBJECTIVES: This study aimed to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) in assessing small bowel (SB) Crohn disease (CD). MATERIALS AND METHODS: We systematically searched PubMed, Elsevier, ScienceDirect, Karger, Web of Science, Wiley Online Library, and Springer for studies in which CT or MRI were evaluated to assess SB CD. Bivariate random effect meta-analytic methods were used to estimate pooled sensitivity, specificity, and receiver operating characteristic curves...
June 5, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28577319/diffusion-kurtosis-mri-versus-conventional-diffusion-weighted-imaging-for-evaluating-inflammatory-activity-in-crohn-s-disease
#4
Li Huang, Xue-Hua Li, Si-Yun Huang, Zhong-Wei Zhang, Xu-Feng Yang, Jin-Jiang Lin, Meng-Jie Jiang, Shi-Ting Feng, Can-Hui Sun, Zi-Ping Li
PURPOSE: To assess the efficacy of diffusion kurtosis imaging (DKI) and to compare DKI-derived parameters with that of conventional diffusion-weighted imaging (DWI) for grading the inflammatory activity of Crohn's disease (CD). MATERIALS AND METHODS: In all, 38 patients with CD underwent 3T magnetic resonance enterography (MRE) with DKI (b values of 0-2000 s/mm(2) ). The inflammatory activity of the bowel segments was graded by magnetic resonance index of activity (MaRIA) as inactive (<7), mild (≥7 and <11), or moderate-severe (≥11)...
June 3, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28548906/beyond-the-bowel-extraintestinal-manifestations-of-inflammatory-bowel-disease
#5
Jeffrey D Olpin, Brett P Sjoberg, Sarah E Stilwill, Leif E Jensen, Maryam Rezvani, Akram M Shaaban
Inflammatory bowel disease (IBD) is a chronic, relapsing immune-mediated inflammation of the gastrointestinal tract. IBD includes two major disease entities: Crohn disease and ulcerative colitis. Imaging plays an important role in the diagnosis and surveillance of these complex disorders. Computed tomographic and magnetic resonance enterographic techniques have been refined in recent years to provide a superb means of evaluating the gastrointestinal tract for suspected IBD. Although the intestinal imaging manifestations of IBD have been extensively discussed in the radiology literature, extraintestinal imaging manifestations of IBD have received less attention...
May 26, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28512287/levels-of-faecal-calprotectin-and-magnetic-resonance-enterocolonography-correlate-with-severity-of-small-bowel-crohn-s-disease-a-retrospective-cohort-study
#6
Lei Ye, Wei Chen, Bi-Qin Chen, Xing Lan, Shao-Dong Wang, Xiao-Chen Wu, Wei Huang, Fang-Yu Wang
Few studies have evaluated the usefulness of fecal calprotectin (FC) or magnetic resonance enterography (MRE) in diagnosing active Crohn's disease (CD) of the small bowel. In the study, we investigated the reliability of FC and MRE in assessing the activity of ileal CD and further explored the relationship between levels of FC and MRE scores. A total of 221 patients were diagnosed with ileal or ileo-colitis CD in our department between July 2012 and October 2016. The global magnetic resonance index of activity (MaRIA) correlated with the simple endoscopic score for CD (SES-CD) (r = 0...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28512034/diagnostic-yield-of-capsule-endoscopy-versus-magnetic-resonance-enterography-and-small-bowel-contrast-ultrasound-in-the-evaluation-of-small-bowel-crohn-s-disease-systematic-review-and-meta-analysis
#7
REVIEW
Uri Kopylov, Diana E Yung, Tal Engel, Sanju Vijayan, Ofir Har-Noy, Lior Katz, Salvatore Oliva, Tomer Avni, Robert Battat, Rami Eliakim, Shomron Ben-Horin, Anastasios Koulaouzidis
BACKGROUND AND AIMS: Capsule endoscopy (CE), magnetic resonance enterography (MRE) and small bowel (SB) intestinal contrast ultrasound (SICUS) are the modalities of choice for SB evaluation. This study aimed to compare the diagnostic yield (DY) of CE to MRE and SICUS in detection and monitoring of SB CD through meta-analysis of the available literature. METHODS: We performed a systematic literature search for trials comparing the accuracy of CE, MRE and SICUS for detection of active SB inflammation in patients with suspected and/or established CD...
April 27, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28506799/diffusion-weighted-imaging-in-quiescent-crohn-s-disease-correlation-with-inflammatory-biomarkers-and-video-capsule-endoscopy
#8
E Klang, U Kopylov, R Eliakim, N Rozendorn, D Yablecovitch, A Lahat, S Ben-Horin, M M Amitai
AIM: To investigate the role of restricted diffusion in quiescent Crohn's disease (CD) patients and its association with inflammatory biomarkers and endoscopic disease. MATERIAL AND METHODS: Fifty-two quiescent CD patients prospectively underwent magnetic resonance enterography (MRE) and video capsule endoscopy (VCE) and were tested for the inflammatory biomarkers, faecal calprotectin (FCP) and C-reactive protein (CRP). Restricted diffusion in the distal ileum was qualitatively (absence/presence) and quantitatively (apparent diffusion coefficient [ADC]) assessed by two readers...
May 13, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28506472/gadolinium-accumulation-after-contrast-enhanced-magnetic-resonance-imaging-which-implications-in-patients-with-crohn-s-disease
#9
Edoardo Savarino, Vito Chianca, Giorgia Bodini, Domenico Albano, Carmelo Messina, Gian Eugenio Tontini, Luca Maria Sconfienza
Crohn's disease (CD) is a chronic inflammatory condition of the bowel, characterized by an alternation of remission and relapse phases, leading to a progressive intestinal damage with loss of function. Magnetic resonance enterography has been widely used in the past for the evaluation of fistulizing disease, but its use increased over time, being considered helpful in different moments of disease course. Intravenous injection of Gadolinium-based contrast agents has been demonstrated to be crucial to assess mucosal inflammation, transmural involvement, and extraintestinal disease...
April 26, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28498158/transmural-healing-is-associated-with-improved-long-term-outcomes-of-patients-with-crohn-s-disease
#10
Samuel R Fernandes, Rita V Rodrigues, Sónia Bernardo, João Cortez-Pinto, Isadora Rosa, João P da Silva, Ana R Gonçalves, Ana Valente, Cilénia Baldaia, Paula M Santos, Luís Correia, José Venâncio, Paula Campos, António D Pereira, José Velosa
BACKGROUND: Mucosal healing (MH) is currently accepted as one of the best treatment targets in Crohn's disease. However, even in patients with sustained MH, residual bowel wall inflammation can still be detected by cross-sectional imaging. The long-term benefits of obtaining transmural healing (TH) have not been previously assessed. METHODS: We performed an observational study including 214 patients with Crohn's disease with a magnetic resonance enterography (MRE) and colonoscopy performed within a 6-month interval...
May 11, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28457088/feasibility-of-bedside-bowel-ultrasound-performed-by-a-gastroenterologist-for-detection-and-follow-up-of-inflammatory-bowel-disease
#11
Dan Carter, Rami Eliakim
BACKGROUND: Bowel ultrasound has several possible uses in inflammatory bowel disease (IBD), including the initial evaluation of suspected IBD, monitoring of therapeutic response, detection of relapse, and diagnosis of complications as well as of extra-intestinal manifestations. However, its use has been limited mainly to countries where it is performed by the attending physician. OBJECTIVES: To investigate the feasibility and sensitivity of bedside bowel ultrasound performed by a gastroenterologist for assessing disease activity and complications in IBD...
March 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28447964/a-rare-cause-of-acute-gastrointestinal-hemorrhage-ileal-lipoma-case-report
#12
E Manna, Fabrizio Maria Frattaroli, E Polettini, Aldo Nunziale, Giuseppe Pappalardo
Primary small bowel tumors account for 1-6% of all Gastrointestinal (G.I.) tract malignancies. Among these pedunculated lipomas are unusual. We report a case of a 66-year-old male with a history of G.I. hemorrhage and acute anemia, negative upper and lower endoscopies and a pedunculated lipoma in distal ileum, revealed by CT enterography. The patient was successfully treated by open surgery. Patients with G.I. hemorrhage and negative upper and lower endoscopies need an accurate evaluation of small bowel. Multislice CT enterography or Magnetic Resonance enteroclysis/ enterography represent the fastest and more accurate tools to obtain an exhaustive evaluation of small bowel...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28445795/a-novel-approach-to-calculating-small-intestine-length-based-on-magnetic-resonance-enterography
#13
Nicole A Wilson, Hyung-Soon Park, Kyoung Soub Lee, Lauren K Barron, Brad W Warner
BACKGROUND: Bowel length is an important factor in the management of patients with intestinal failure and short bowel syndrome. However, it is difficult to accurately measure the length of the small intestine. Our aim was to demonstrate the feasibility of a dedicated software algorithm for calculating small intestine length based on magnetic resonance enterography (MRE) images. STUDY DESIGN: A custom algorithm for image thresholding, wall identification, segmentation, and path extraction was designed and implemented...
April 23, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28417181/colonic-inflammation-in-pediatric-inflammatory-bowel-disease-detection-with-magnetic-resonance-enterography
#14
Alessandro Campari, Marcello Napolitano, Giovanna Zuin, Luciano Maestri, Giovanni Di Leo, Francesco Sardanelli
BACKGROUND: Colonic involvement in pediatric inflammatory bowel disease is common. Magnetic resonance (MR) enterography is considered the best imaging modality for pediatric inflammatory bowel disease evaluation. It is unclear whether the lack of a dedicated large bowel preparation prevents a reliable colonic assessment. OBJECTIVE: To determine the diagnostic performance of standard MR enterography in detecting and grading colonic inflammatory activity. MATERIALS AND METHODS: We retrospectively evaluated children who underwent both MR enterography and ileocolonoscopy with biopsies <4 weeks apart...
June 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28386628/paediatric-magnetic-resonance-enteroclysis-under-general-anaesthesia-initial-experience
#15
Sophie Sadigh, Mark Chopra, Michael R Sury, Neil Shah, Øystein E Olsen, Tom A Watson
MR enterography is the accepted imaging reference standard for small bowel assessment in inflammatory bowel disease. There is an increasing cohort of children with inflammatory bowel disease presenting at an early age (<5 years) with severe disease. Younger children present a technical challenge for enterography because of the need for sedation/general anaesthesia to allow image optimisation and the need for oral contrast to allow adequate luminal assessment. Through our experiences, MR enteroclysis under general anaesthesia has proven to be a successful imaging technique for the work-up of these patients...
April 6, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28362690/perianal-pediatric-crohn-s-disease-is-associated-with-a-distinct-phenotype-and-greater-inflammatory-burden
#16
Amit Assa, Michal Amitai, Mary-Louise Greer, Denise A Castro, Ruth Cytter Kuint, Maria Martínez-León, Izabela Herman-Sucharska, Eva Coppenrath, Sudha Anupindi, Alexander Towbin, Douglas Moote, Osnat Konen, Li-Tal Pratt, Anne Griffiths, Dan Turner
BACKGROUND: Data on the outcomes of children with perianal Crohn's disease (pCD) are limited, although its presence is often used for justifying early use of biologics. We aimed to assess whether pCD in children is associated with more severe outcomes as found in adults. METHODS: Data were extracted from the ImageKids database, a prospective, multicenter, longitudinal cohort study. The study enrolled 246 children at disease onset or thereafter. All patients underwent comprehensive clinical, endoscopic, and radiologic evaluation at enrollment; 98 children had repeat evaluation at 18 months...
March 30, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28347526/the-role-of-imaging-in-the-preoperative-assessment-of-children-with-inflammatory-colitis
#17
Natashia M Seemann, Shilpa Radhakrishnan, Aaron Gazendam, Sebastian K King, Michelle Falkiner, Nicholas Shkumat, Mary-Louise C Greer, Jacob C Langer
BACKGROUND: Accurate diagnosis of Crohn's disease or ulcerative colitis is essential for surgical planning. This study compared the accuracy, safety, and utility of small bowel follow-through (SBFT) and magnetic resonance enterography (MRE) for detecting small bowel (SB) involvement preoperatively. METHODS: A retrospective review of children who underwent colectomy for inflammatory bowel disease (2000-2014) was performed. Preoperative SBFT and MRE were independently reviewed by two radiologists blinded to clinical data...
June 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28334618/is-there-a-role-of-magnetic-resonance-imaging-in-deciding-to-stop-anti-tumor-necrosis-factor-treatment-in-ileal-crohn-s-disease
#18
Jose C Gallego, Ana Echarri
PURPOSE: This study was performed to assess the ability of magnetic resonance enterography to predict the evolution of patients in whom anti-tumor necrosis factor-α therapy was suspended. METHODS: A prospective study of patients with ileal Crohn's disease was performed. RESULTS: Twenty-nine patients were included. Patients who later relapsed showed higher magnetic resonance scores than those who did not relapse (4.2 vs. 2.5, respectively; p<0...
May 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28302273/there-is-good-agreement-between-mr-enterography-and-bowel-ultrasound-with-regards-to-disease-location-and-activity-in-paediatric-inflammatory-bowel-disease
#19
COMPARATIVE STUDY
J L Barber, J Maclachlan, K Planche, M Furman, D Crespi, N Bab, I Beal
AIM: To investigate concordance of bowel ultrasound and magnetic resonance enterography (MRE) in identifying active disease in children with inflammatory bowel disease. MATERIALS AND METHODS: The imaging of children with inflammatory bowel disease who had undergone bowel ultrasound and MRE within 30 days were retrospectively reviewed, from January 2009 to November 2015. Ultrasound was without oral contrast medium; MRI was conducted with patients unsedated with oral contrast medium and gadolinium...
July 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28298964/magnetic-resonance-enterography-in-crohn-s-disease-how-we-do-it-and-common-imaging-findings
#20
REVIEW
Annalisa Mantarro, Paola Scalise, Elisa Guidi, Emanuele Neri
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract, with unpredictable clinical course by phases of relapses alternating with other of quiescence. The etiology is multifactorial and is still not completely known; globally the westernization of lifestyle is causing an increasing incidence of CD, with peak age of 20-30 years. The diagnostic workup begins with the evaluation of the clinical history, physical examination and laboratory tests. However, the clinical assessment is subjected interobserver variability and, occasionally, the symptoms of acute and chronic inflammation may be indistinguishable...
February 28, 2017: World Journal of Radiology
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