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https://www.readbyqxmd.com/read/28629982/polymeric-nanoparticles-promising-platform-for-drug-delivery
#1
REVIEW
Khalid M El-Say, Hossam S El-Sawy
Nano medicine had viewed countless breakthroughs in drug delivery implementations. The main objective of nanotechnology application in delivering and carrying many promising therapeutics is to assure drugs carriage to their action sites, to maximize the pharmacological desired influence of remedies and to overcome their limitations and drawbacks that would hinder the required effectiveness. One of these applications was the particulates type of nano-range in size and tremendous impact in achievement. About this specific diversity of particulates, the different elaboration methodologies, mandatory and elementary components for design, and examples of splendid success stories for these particulates were emphasized in this humble review...
June 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28615200/kallikrein-related-peptidase-5-contributes-to-h3n2-influenza-virus-infection-in-human-lungs
#2
Melia Magnen, Fabien Gueugnon, Antoine Guillon, Thomas Baranek, Virginie C Thibault, Agnès Petit-Courty, Simon J de Veer, Jonathan Harris, Alison A Humbles, Mustapha Si-Tahar, Yves Courty
The HA (hemagglutinin) of influenza virus must be activated by proteolysis before the virus can become infectious. Previous studies have indicated that HA cleavage is driven by membrane-bound or extracellular serine proteases in the respiratory tract. However, there is still uncertainty as to which proteases are critical for activating the HA of seasonal influenza A viruses (IAV) in humans. This study focuses on human KLK1 and KLK5, two of the 15 serine proteases known as the kallikrein-related peptidases (KLK)...
June 14, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28579868/evidence-based-brief-obsessive-compulsive-scale
#3
COMMENT
Susanne Bejerot, Gunnar Edman, Louise Frisén, Mats Humble
No abstract text is available yet for this article.
2017: Journal of Central Nervous System Disease
https://www.readbyqxmd.com/read/28569703/scholars-versus-practitioners-anchor-proof-testing-and-the-birth-of-a-mixed-culture-in-eighteenth-century-france
#4
Arnaud Orain, Sylvain Laubé
In line with studies that question the conventional dichotomies between "head" and "hand," this article analyzes the emergence of a mixed naval culture, between science and technology, during the French Enlightenment. The case at issue is that of the circuitous development of an anchor proof testing protocol, an important method in the competition for maritime supremacy used at least until the first third of the nineteenth century. The story begins in the dockyard of Brest with a humble boatswain, and continues with the dissemination of his experiments thanks to prominent figures of the Naval Academy of Brest and of the Royal Academy of Sciences of Paris...
2017: Technology and Culture
https://www.readbyqxmd.com/read/28557932/humbled
#5
J S Desai
No abstract text is available yet for this article.
June 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28537164/all-the-world-s-a-stage
#6
Jane Bates
Whenever an actor describes their job as hard work, I have been known to guffaw ungenerously. But I have had to eat humble pie.
May 24, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28499371/-placebo-effect-is-probably-what-we-refer-to-as-patient-healing-power-a-qualitative-pilot-study-examining-how-norwegian-complementary-therapists-reflect-on-their-practice
#7
Trine Stub, Nina Foss, Ingrid Liodden
BACKGROUND: Complementary therapists spend considerable time with their patients, especially in the first consultation. The communication between patients and their therapists is important for raising consciousness and activation of the patient's self-healing power. Thus, the aims in this study were to delineate what complementary therapists regard as essential in patient consultations, their view of the healing process, and how the therapists understand the placebo effect and its position in the healing process...
May 12, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28450479/judges-humbled-by-lengths-to-which-people-go-to-improve-animals-lives
#8
(no author information available yet)
No abstract text is available yet for this article.
April 29, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28378684/-you-can-t-help-but-be-humbled-by-how-our-staff-responded
#9
Erin Dean
When nurses, colleagues and patients found themselves drawn into the centre of the terrorist attack in Westminster last month, just metres from a major London hospital, their response was admirable.
April 5, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28340075/a-rainbow-of-extra-tubes-useful-or-wasteful-practice
#10
Robert M Humble, Scott R Davis, Hermann G Hounkponou, Matthew D Krasowski
No abstract text is available yet for this article.
March 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28333520/plan-pray
#11
Lisa S Gussak
Presents a poem the author wrote about patient she encountered who made her feel humbled. The experience she had with this young woman led her to reflect on the similarities and differences in their lives. The author connected with the patient as a woman who dreams of an easier life for her children and in their shared belief in the power of prayer to bring comfort. (PsycINFO Database Record
March 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/28329584/reusing-surgical-instruments-during-mohs-micrographic-surgery-safe-from-infection-but-not-free-from-risk
#12
Tatyana A Petukhova, Thomas H King, Kenny J Omlin, Daniel B Eisen
We report several scenarios of compromise in patient safety owing to the re-use of mis-assigned patient's surgical instruments in Mohs micrographic surgery.We discuss the breaks in universal protocols that others may experience in their practices and describe corrective measures that our institutions employed to avoid such future events.There is a lack of publication in the literature on the topic of mis-assigned instrument use in Mohs surgery. We believe that the  practice of re-using instruments is cost-effective and therefore common...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328603/simultaneous-autologus-mandible-and-temporomandibular-joint-reconstruction
#13
Yigit Ozer Tiftikcioglu, Ersin Gur, Ufuk Bilkay
Ablative surgery of mandible often necessitates combined reconstruction of the mandible and the temporomandibular joint. Fibula-free flaps with gap arthroplasty or osseochondral grafts are common procedures in the authors' practice. In search for a better reconstructive option free fibula flap is used together with a metatarsal bone flap for the vascular reconstruction of the mandibular body and the condyle at the same time. The 2 osseous-free flaps have been fused and used as a combined flow through double-free flap...
June 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28302153/students-as-effective-harm-reductionists-and-needle-exchange-organizers
#14
EDITORIAL
Kyle Barbour, Miriam McQuade, Brandon Brown
BACKGROUND: Needle exchange programs are safe, highly effective programs for promoting health among people who inject drugs. However, they remain poorly funded, and often illegal, in many places worldwide due to fear and stigma surrounding drug use. Continued advocacy, education, and implementation of new needle exchanges are thus essential to improve public health and reduce structural inequality. COMMENTARY: We argue that students, and especially professional and graduate students, have the potential to play an important role in advancing harm reduction...
March 17, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28236555/development-of-a-low-level-39-ar-calibration-standard-analysis-by-absolute-gas-counting-measurements-augmented-with-simulation
#15
R M Williams, C E Aalseth, J M Brandenberger, A R Day, E Finn, E S Fuller, E W Hoppe, P H Humble, M E Keillor, E K Mace, A W Myers, C T Overman, M E Panisko, A Seifert, S K White
This paper describes the generation of (39)Ar, via reactor irradiation of potassium carbonate, followed by quantitative analysis (length-compensated proportional counting) to yield two calibration standards that are respectively 50 and 3 times atmospheric background levels. Measurements were performed in Pacific Northwest National Laboratory's shallow underground counting laboratory studying the effect of gas density on beta-transport; these results are compared with simulation. The total expanded uncertainty of the specific activity for the ~50× (39)Ar in P10 standard is 3...
February 17, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28225399/poster-creation-guidelines-and-tips-for-success
#16
Cindy Kohtz, Carrie Hymer, Patricia Humbles-Pegues
No abstract text is available yet for this article.
March 2017: Nursing
https://www.readbyqxmd.com/read/28211745/superdense-coding-over-optical-fiber-links-with-complete-bell-state-measurements
#17
Brian P Williams, Ronald J Sadlier, Travis S Humble
Adopting quantum communication to modern networking requires transmitting quantum information through a fiber-based infrastructure. We report the first demonstration of superdense coding over optical fiber links, taking advantage of a complete Bell-state measurement enabled by time-polarization hyperentanglement, linear optics, and common single-photon detectors. We demonstrate the highest single-qubit channel capacity to date utilizing linear optics, 1.665±0.018, and we provide a full experimental implementation of a hybrid, quantum-classical communication protocol for image transfer...
February 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28186333/the-exponential-growth-of-autophagy-related-research-from-the-humble-yeast-to-the-nobel-prize
#18
Noboru Mizushima
Autophagy was discovered more than half a century ago. In the early days, autophagy was studied mostly through the use of biochemical methods and electron microscopy. In the 1990s, yeast genetics was introduced to this field and brought about an exponential expansion. The 2016 Nobel Prize in Physiology or Medicine was eventually awarded to the scientist who spearheaded the rapid development of the field: Yoshinori Ohsumi. Here, I describe in a Nutshell how the autophagy machinery was discovered and how the autophagy research field has grown following the breakthroughs from yeast studies...
March 2017: FEBS Letters
https://www.readbyqxmd.com/read/28147436/from-humble-beginnings-%C3%A2-the-evolution-of-the-fracs-urology
#19
Athina Pirpiris, Amanda S J Chung, Prem Rashid
BACKGROUND: Surgery has a rich and colourful history dating as far back as, at least, the Neolithic period. There have been many advances in knowledge and technology, as well as changes to working conditions and public perception and expectations. The urology training programme is jointly managed by the Royal Australasian College of Surgeons and the Urological Society of Australia and New Zealand. Urological training in Australia and New Zealand has undergone a number of changes over the years...
February 1, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28138444/conscience-imperative-of-providing-information-and-knowledge-in-hepatology-the-portuguese-approach
#20
Guilherme Macedo, Marco Silva
The last 25 years have been a thrilling time for the Portuguese hepatologists. Our national meetings have been providing the forum for the exchange of scientific ideas and the presentation of clinical research in clinical Hepatology, a growing world of knowledge in medical care. Bridging the gaps between technology and clinical daily practice, the latest development and the almost humble bedside care, has been a challenge for the increasing numbers of doctors devoted to the diagnostic and treatment of liver disease...
January 16, 2017: World Journal of Clinical Cases
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