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https://www.readbyqxmd.com/read/28703922/sensitivity-evaluation-and-selective-plane-imaging-geometry-for-x-ray-induced-luminescence-imaging
#1
Bryan P Quigley, Corey D Smith, Shih-Hsun Cheng, Jeffrey S Souris, Charles A Pelizzari, Chin-Tu Chen, Leu-Wei Lo, Chester S Reft, Rodney D Wiersma, Patrick J La Riviere
PURPOSE: X-ray induced luminescence (XIL) is a hybrid X-ray/optical imaging modality that employs nanophosphors that luminescence in response to X-ray irradiation. X-ray-activated phosphorescent nanoparticles have potential applications in radiation therapy as theranostics, nanodosimeters, or radiosensitizers. Extracting clinically relevant information from the luminescent signal requires the development of a robust imaging model that can determine nanophosphor distributions at depth in an optically scattering environment from surface radiance measurements...
July 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28610689/experimental-assessment-of-proton-dose-calculation-accuracy-in-inhomogeneous-media
#2
J Sorriaux, M Testa, H Paganetti, J Orban de Xivry, J A Lee, E Traneus, K Souris, S Vynckier, E Sterpin
PURPOSE: Proton therapy with Pencil Beam Scanning (PBS) has the potential to improve radiotherapy treatments. Unfortunately, its promises are jeopardized by the sensitivity of the dose distributions to uncertainties, including dose calculation accuracy in inhomogeneous media. Monte Carlo dose engines (MC) are expected to handle heterogeneities better than analytical algorithms like the pencil-beam convolution algorithm (PBA). In this study, an experimental phantom has been devised to maximize the effect of heterogeneities and to quantify the capability of several dose engines (MC and PBA) to handle these...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28496466/validated-spectrophtometric-method-for-simultaneous-determination-of-buprenorphine-and-naloxone-in-pharmaceutical-dosage-forms
#3
Effat Souri, Farzaneh Sadat Ahmadi, Maliheh Barazandeh Tehrani, Majid Mohammad Hosseini, Sedigheh Fadaye Vatan
Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence. In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of buprenorphine hydrochloride and naloxone hydrochloride in tablets. The measurements were carried out at wavelengths of 257...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28495517/berberine-confers-neuroprotection-in-coping-with-focal-cerebral-ischemia-by-targeting-inflammatory-cytokines
#4
Solmaz Nasseri Maleki, Nahid Aboutaleb, Faramarz Souri
SCOPE: Existing research indicates that anti-inflammatory and antioxidant properties of berberine play major roles in coping with oxidative stress in neurodegenerative diseases, but it is not known if this isoquinoline alkaloid affects inflammatory cytokines such as interleukin 10 in focal cerebral ischemia. METHODS AND RESULTS: Male Wistar rats (10 weeks old) were treated with 40mg/kg concentration of berberine 1h after focal cerebral ischemia and the anti-inflammatory properties of berberine were evaluated by immunohistochemical analysis, water content measure and behavioral tests...
May 8, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28494013/modeling-spatial-variation-in-risk-of-presence-and-insecticide-resistance-for-malaria-vectors-in-laos
#5
Marc Souris, Sébastien Marcombe, Julie Laforet, Paul T Brey, Vincent Corbel, Hans J Overgaard
Climatic, sociological and environmental conditions are known to affect the spatial distribution of malaria vectors and disease transmission. Intensive use of insecticides in the agricultural and public health sectors exerts a strong selective pressure on resistance genes in malaria vectors. Spatio-temporal models of favorable conditions for Anopheles species' presence were developed to estimate the probability of presence of malaria vectors and insecticide resistance in Lao PDR. These models were based on environmental and meteorological conditions, and demographic factors...
2017: PloS One
https://www.readbyqxmd.com/read/28488470/antioxidant-enzymes-responses-in-shoots-of-arsenic-hyperaccumulator-isatis-cappadocica-desv-under-interaction-of-arsenate-and-phosphate
#6
Zahra Souri, Naser Karimi, Letúzia M de Oliveira
The present study investigated the effects of arsenate and phosphate interaction on growth, lipid peroxidation, arsenic (As) accumulation, phosphorus (P) accumulation, and the activities of some antioxidant enzymes in Isatis cappadocica. Plants were exposed to (50-1200 μmol L(-1)) arsenate and (5-1600 μmol L(-1)) phosphate for 28 days in a hydroponic system. At a phosphate concentration of 1600 µM, biomass production and chlorophyll content increased, demonstrating clearly that phosphate was able to provide protection against As toxicity...
May 27, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28484145/comparison-the-effects-of-poor-health-and-low-income-on-early-retirement-a-systematic-review-and-meta-analysis
#7
Enayatollah Homaie Rad, Arash Rashidian, Mohamad Arab, Ali Souri
The main aim of this study was to estimate the effects of poor health and low income on early retirement. For this purpose systematic review and meta-analysis were conducted. Web of Science, PUBMED and Scopus databases were searched systematically. Finally 17 surveys were added in meta-analysis. These studies were conducted in 13 countries. At the end a Meta regression was done to show the effects of welfare system type on effect sizes of poor health and low income. The results of this study showed that poor health had effect on the risk of early retirement...
May 9, 2017: Industrial Health
https://www.readbyqxmd.com/read/28381771/oil-characteristics-of-four-palestinian-olive-varieties
#8
Enrico Maria Lodolini, Serena Polverigiani, Saed Ali, Mohammed Mutawea, Mayyada Qutub, Taysir Arabasi, Fabio Pierini, Mohammed Abed, Davide Neri
Olive oil represents an important source of income for Palestinian farmers in local, national and international markets. Sometimes, olive oil produced in local climatic conditions, does not achieve the International Olive Council (IOC) trade standards so that international markets are precluded. The oil chemical composition and sensory profile of four Palestinian olive varieties (Nabali Baladi, Nabali Mohassan, Souri and K18) were characterized in 2010 throughout an in situ evaluation. Most of the physic-chemical characteristics and the fatty acid composition of the varieties met the International Olive Council trade standards (IOC-TS) for extra virgin olive oils...
April 4, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28380473/successful-management-of-a-patient-with-autoimmune-hemorrhaphilia-due-to-anti-factor-xiii-13-antibodies-complicated-by-pulmonary-thromboembolism
#9
Yoshiyuki Ogawa, Kunio Yanagisawa, Masayoshi Souri, Masahiro Mihara, Chiaki Naito, Makiko Takizawa, Takuma Ishizaki, Takeki Mitsui, Hiroshi Handa, Tsukasa Osaki, Yoshihisa Nojima, Akitada Ichinose
Autoimmune hemophilia-like disease (hemorrhaphilia) due to anti-factor XIII (FXIII) antibodies (AH13) is a very rare, life-threatening bleeding disorder. A 77-year-old woman developed macrohematuria and a right renal pelvic hematoma. The coagulation times were not prolonged, but FXIII activity and antigen levels were severely and moderately reduced to 9 and 29% of normal values, respectively. Accordingly, the FXIII-specific activity turned out to be low. FXIII inhibitor and anti-FXIII-A subunit autoantibodies were detected by a 1:1 crossmixing test and immunoblot and immunochromatographic assays...
2017: Acta Haematologica
https://www.readbyqxmd.com/read/28363770/lectin-functionalized-mesoporous-silica-nanoparticles-for-endoscopic-detection-of-premalignant-colonic-lesions
#10
Nai-Tzu Chen, Jeffrey S Souris, Shih-Hsun Cheng, Chia-Hui Chu, Yu-Chao Wang, Vani Konda, Urszula Dougherty, Marc Bissonnette, Chung-Yuan Mou, Chin-Tu Chen, Leu-Wei Lo
Colorectal cancer (CRC) is one of the leading causes of cancer-deaths worldwide. Methods for the early in situ detection of colorectal adenomatous polyps and their precursors - prior to their malignancy transformation into CRC - are urgently needed. Unfortunately at present, the primary diagnostic method, colonoscopy, can only detect polyps and carcinomas by shape/morphology; with sessile polyps more likely to go unnoticed than polypoid lesions. Here we describe our development of polyp-targeting, fluorescently-labeled mesoporous silica nanoparticles (MSNs) that serve as targeted endoscopic contrast agents for the early detection of colorectal polyps and cancer...
March 29, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28349615/development-and-perceived-effects-of-an-educational-programme-on-quality-and-safety-in-medication-handling-in-residential-facilities
#11
Anna Mygind, Mira El-Souri, Charlotte Rossing, Linda Aagaard Thomsen
OBJECTIVES: To develop and test an educational programme on quality and safety in medication handling for staff in residential facilities for the disabled. METHODS: The continuing pharmacy education instructional design model was used to develop the programme with 22 learning objectives on disease and medicines, quality and safety, communication and coordination. The programme was a flexible, modular seven + two days' course addressing quality and safety in medication handling, disease and medicines, and medication supervision and reconciliation...
March 27, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28293047/personality-driving-behavior-and-mental-disorders-factors-as-predictors-of-road-traffic-accidents-based-on-logistic-regression
#12
Seyyed Salman Alavi, Mohammad Reza Mohammadi, Hamid Souri, Soroush Mohammadi Kalhori, Fereshteh Jannatifard, Ghazal Sepahbodi
BACKGROUND: The aim of this study was to evaluate the effect of variables such as personality traits, driving behavior and mental illness on road traffic accidents among the drivers with accidents and those without road crash. METHODS: In this cohort study, 800 bus and truck drivers were recruited. Participants were selected among drivers who referred to Imam Sajjad Hospital (Tehran, Iran) during 2013-2015. The Manchester driving behavior questionnaire (MDBQ), big five personality test (NEO personality inventory) and semi-structured interview (schizophrenia and affective disorders scale) were used...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28195015/the-effect-of-catastrophic-health-expenditure-on-work-after-retirement
#13
Enayatollah Homaie Rad, Arash Rashidian, Mohamad Arab, Ali Souri
Several factors can force retirees to go to paid work. Catastrophic health-care expenditure (CHCE) is one of the driving forces for retirees to go to paid work. This cross-sectional study was based on 6,307 Iran retirees' data. Xu method was used to calculate CHCE, and a logit model was estimated to show the association between CHCE and bridge employment. Other control variables were added to the model. The findings showed that there was positive relationship between CHCE and bridge employment. Retirement pension had negative relationship with work after retirement...
March 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28166755/testing-the-potential-significance-of-different-scion-rootstock-genotype-combinations-on-the-ecology-of-old-cultivated-olive-trees-in-the-southeast-mediterranean-area
#14
Oz Barazani, Yoni Waitz, Yizhar Tugendhaft, Michael Dorman, Arnon Dag, Mohammed Hamidat, Thameen Hijawi, Zohar Kerem, Erik Westberg, Joachim W Kadereit
BACKGROUND: A previous multi-locus lineage (MLL) analysis of SSR-microsatellite data of old olive trees in the southeast Mediterranean area had shown the predominance of the Souri cultivar (MLL1) among grafted trees. The MLL analysis had also identified an MLL (MLL7) that was more common among rootstocks than other MLLs. We here present a comparison of the MLL combinations MLL1 (scion)/MLL7 (rootstock) and MLL1/MLL1 in order to investigate the possible influence of rootstock on scion phenotype...
February 6, 2017: BMC Ecology
https://www.readbyqxmd.com/read/28133755/evaluation-of-motion-mitigation-using-abdominal-compression-in-the-clinical-implementation-of-pencil-beam-scanning-proton-therapy-of-liver-tumors
#15
Liyong Lin, Kevin Souris, Minglei Kang, Adam Glick, Haibo Lin, Sheng Huang, Kristin Stützer, Guillaume Janssens, Edmond Sterpin, John A Lee, Timothy D Solberg, James E McDonough, Charles B Simone, Edgar Ben-Josef
PURPOSE: To determine whether individual liver tumor patients can be safely treated with pencil beam scanning proton therapy. This study reports a planning preparation workflow that can be used for beam angle selection and the evaluation of the efficacy of abdominal compression (AC) to mitigate motion. METHODS: Four-dimensional computed tomography scans (4DCT) with and without AC were available from 10 liver tumor patients with fluoroscopy-proven motion reduction by AC, previously treated using photons...
February 2017: Medical Physics
https://www.readbyqxmd.com/read/28095031/the-role-of-drug-and-alcohol-use-and-the-risk-of-motor-vehicle-crashes-in-shiraz-iran-2014-a-case-crossover-study
#16
Narges Khanjani, Masoomeh Mousavi, Amirreza Dehghanian, Yunes Jahani, Hamid Souri
BACKGROUND: Traffic accidents and traffic-related injuries and mortality have become a major public health concern in Iran. This study aimed to examine the role of drug and alcohol use in motor vehicle accidents in Iran. METHODS: This case-crossover study was conducted on 441 drivers who survived a road traffic crash and were taken to the emergency department of Shahid Rajaee trauma hospital in Shiraz, southern Iran. Data were collected using checklists that included demographic characteristics and drug and alcohol use prior to driving...
August 18, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28092442/upconverted-photosensitization-of-tb-visible-emission-by-nir-yb-excitation-in-discrete-supramolecular-heteropolynuclear-complexes
#17
Nabila Souri, Pingping Tian, Carlos Platas-Iglesias, Ka-Leung Wong, Aline Nonat, Loïc J Charbonnière
Addition of Tb(3+) salts to a solution of a (YbLD) complex in D2O resulted in the formation of [(YbLD)2Tbx] (x = 1 to 3) complexes that, upon NIR excitation at 980 nm, showed an unprecedented Yb to Tb upconversion sensitization phenomenon resulting in the observation of the typical green emission of Tb.
February 1, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28048860/su-f-p-54-guidelines-to-check-image-registration-qa-of-a-clinical-deformation-registration-software-a-single-institution-preliminary-study
#18
G Gill, S Souri, A Rea, Y Chen, J Antone, X Qian, A Riegel, P Taylor, M Marrero, F Diaz, Y Cao, A Jamshidi, S Barley, V Sorell, G Karangelis, T Button, E Klein
PURPOSE: The objective of this study is to verify and analyze the accuracy of a clinical deformable image registration (DIR) software. METHODS: To test clinical DIR software qualitatively and quantitatively, we focused on lung radiotherapy and analyzed a single (Lung) patient CT scan. Artificial anatomical changes were applied to account for daily variations during the course of treatment including the planning target volume (PTV) and organs at risk (OAR). The primary CT (pCT) and the structure set (pST) was deformed with commercial tool (ImSimQA-Oncology Systems Limited) and after artificial deformation (dCT and dST) sent to another commercial tool (VelocityAI-Varian Medical Systems)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047521/su-f-t-52-study-of-energy-dependent-effect-of-dosimetry-systems-used-in-therapeutic-soft-x-ray-energy-range
#19
S Souri, X Qian, G Gill, A Jamshidi, Y Cao, Y Chen
PURPOSE: To investigate energy dependent effects of different dosimetry systems which can be used as in vivo dosimetry monitoring for intraoperative radiotherapy in therapeutic soft x-ray energy range. METHODS: Three dosimetry systems were evaluated in therapeutic soft x-ray energy range: optically stimulated luminescent dosimeter (OSLD) nanoDots, radiochromic EBT2 and EBT3 films. The x-ray photons were produced by a Zeiss Intrabeam 50 kV x-ray radiotherapy system...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047427/su-f-t-121-abdominal-compression-effectively-reduces-the-interplay-effect-and-enables-pencil-beam-scanning-proton-therapy-of-liver-tumors
#20
K Souris, A Glick, M Kang, G Janssens, E Sterpin, H Lin, J McDonough, C Simone, T Solberg, E Ben-Josef, J Lee, L Lin
PURPOSE: To study if abdominal compression can reduce breathing motion and mitigate interplay effect in pencil beam scanning proton therapy (PBSPT) treatment of liver tumors in order to better spare healthy liver volumes compared with photon therapy. METHODS: Ten patients, six having large tumors initially treated with IMRT and four having small tumors treated with SBRT, were replanned for PBSPT. ITV and beam-specific PTVs based on 4D-CT were used to ensure target coverage in PBSPT...
June 2016: Medical Physics
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