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https://www.readbyqxmd.com/read/29785084/impact-of-virtual-reality-simulation-on-learning-barriers-of-phacoemulsification-perceived-by-residents
#1
Danny Siu-Chun Ng, Zihan Sun, Alvin Lerrmann Young, Simon Tak-Chuen Ko, Jerry Ka-Hing Lok, Timothy Yuk-Yau Lai, Shameema Sikder, Clement C Tham
Objective: To identify residents' perceived barriers to learning phacoemulsification surgical procedures and to evaluate whether virtual reality simulation training changed these perceptions. Design: The ophthalmology residents undertook a simulation phacoemulsification course and proficiency assessment on the Eyesi system using the previously validated training modules of intracapsular navigation, anti-tremor, capsulorrhexis, and cracking/chopping. A cross-sectional, multicenter survey on the perceived difficulties in performing phacoemulsification tasks on patients, based on the validated International Council of Ophthalmology's Ophthalmology Surgical Competency Assessment Rubric (ICO-OSCAR), using a 5-point Likert scale (1 = least and 5 = most difficulty), was conducted among residents with or without prior simulation training...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29780334/an-innovative-framework-for-delivering-psychotherapy-to-patients-with-treatment-resistant-posttraumatic-stress-disorder-rationale-for-interactive-motion-assisted-therapy
#2
Marieke J van Gelderen, Mirjam J Nijdam, Eric Vermetten
Despite an array of evidence-based psychological treatments for patients with a posttraumatic stress disorder (PTSD), a majority of patients do not fully benefit from the potential of these therapies. In veterans with PTSD, up to two-thirds retain their diagnosis after psychotherapy and often their disorder is treatment-resistant, which calls for improvement of therapeutic approaches for this population. One of the factors hypothesized to underlie low response in PTSD treatment is high behavioral and cognitive avoidance to traumatic reminders...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29774657/cheminformatics-in-drug-discovery-an-industrial-perspective
#3
REVIEW
Hongming Chen, Thierry Kogej, Ola Engkvist
Cheminformatics has established itself as a core discipline within large scale drug discovery operations. It would be impossible to handle the amount of data generated today in a small molecule drug discovery project without persons skilled in cheminformatics. In addition, due to increased emphasis on "Big Data", machine learning and artificial intelligence, not only in the society in general, but also in drug discovery, it is expected that the cheminformatics field will be even more important in the future...
May 18, 2018: Molecular Informatics
https://www.readbyqxmd.com/read/29772381/high-gamma-activity-in-the-human-hippocampus-and-parahippocampus-during-inter-trial-rest-periods-of-a-virtual-navigation-task
#4
Yi Pu, Brian R Cornwell, Douglas Cheyne, Blake W Johnson
In rodents, hippocampal cell assemblies formed during learning of a navigation task are observed to re-emerge during resting (offline) periods, accompanied by high-frequency oscillations (HFOs). This phenomenon is believed to reflect mechanisms for strengthening newly-formed memory traces. Using magnetoencephalography recordings and a beamforming source location algorithm (synthetic aperture magnetometry), we investigated high-gamma (80-140 Hz) oscillations in the hippocampal region in 18 human participants during inter-trial rest periods in a virtual navigation task...
May 14, 2018: NeuroImage
https://www.readbyqxmd.com/read/29769058/efficacy-of-standardized-training-on-a-virtual-reality-simulator-to-advance-knee-and-shoulder-arthroscopic-motor-skills
#5
Stefan Rahm, Karl Wieser, David E Bauer, Felix Wa Waibel, Dominik C Meyer, Christian Gerber, Sandro F Fucentese
BACKGROUND: Most studies demonstrated, that training on a virtual reality based arthroscopy simulator leads to an improvement of technical skills in orthopaedic surgery. However, how long and what kind of training is optimal for young residents is unknown. In this study we tested the efficacy of a standardized, competency based training protocol on a validated virtual reality based knee- and shoulder arthroscopy simulator. METHODS: Twenty residents and five experts in arthroscopy were included...
May 16, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29764639/web-based-versus-face-to-face-interprofessional-team-encounters-with-standardized-patients
#6
Kelly A Lempicki, Christine S Holland
BACKGROUND: Challenges exist in developing interprofessional education (IPE) activities including coordinating schedules and obtaining appropriate space for teams to work. Virtual worlds have been explored as a means to overcome some of these challenges. We sought to develop a web-based interprofessional team interaction with a standardized patient (SP), as compared to a face-to-face SP interaction, focusing on the competency area of interprofessional communication. INTERPROFESSIONAL EDUCATION ACTIVITY: Interprofessional teams of students were randomized to complete a web-based or face-to-face SP encounter...
March 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29764633/national-preceptor-development-program-pdp-prototype-the-third-of-a-3-part-series
#7
Craig D Cox, Katrina Mulherin, Sheila Walter
INTRODUCTION: Preceptor development is critical to successful delivery of experiential learning. Although many preceptor development programs exist, a more individualized approach to training is needed. To accomplish this a national preceptor development program should be considered based on the continuing professional development model. A detailed prototype for this program has been described. METHODS: In this final installment of the series, the twelve evidence-based recommendations from the first installment were utilized to construct a prototype for a preceptor development program...
March 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29759077/regulating-pharmaceutical-companies-financial-largesse
#8
REVIEW
Ronen Avraham, Charles Silver
Nissanholtz-Gannot and Yenkellevich (NGY) explore the impact of a 2010 amendment to the Israeli National Health Insurance Law that requires annual reporting of payments from pharmaceutical companies (PCs) to doctors and healthcare organizations. The amendment was adopted to ensure transparency and to facilitate appropriate regulation of interest conflicts. To learn whether the amendment was having the desired effects, NGY interviewed multiple representatives of an assortment of stakeholders. They found broad agreement among the respondents that financial relationships between PCs and physicians should be transparent...
May 14, 2018: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29757973/a-new-strategy-to-control-and-eradicate-undruggable-oncogenic-k-ras-driven-pancreatic-cancer-molecular-insights-and-core-principles-learned-from-developmental-and-evolutionary-biology
#9
REVIEW
Robert E Van Sciver, Michael P Lee, Caroline Dasom Lee, Alex C Lafever, Elizaveta Svyatova, Kevin Kanda, Amber L Colliver, Lauren L Siewertsz van Reesema, Angela M Tang-Tan, Vasilena Zheleva, Monicah N Bwayi, Minglei Bian, Rebecca L Schmidt, Lynn M Matrisian, Gloria M Petersen, Amy H Tang
Oncogenic K-RAS mutations are found in virtually all pancreatic cancers, making K-RAS one of the most targeted oncoproteins for drug development in cancer therapies. Despite intense research efforts over the past three decades, oncogenic K-RAS has remained largely "undruggable". Rather than targeting an upstream component of the RAS signaling pathway (i.e., EGFR/HER2) and/or the midstream effector kinases (i.e., RAF/MEK/ERK/PI3K/mTOR), we propose an alternative strategy to control oncogenic K-RAS signal by targeting its most downstream signaling module, Seven-In-Absentia Homolog (SIAH)...
May 14, 2018: Cancers
https://www.readbyqxmd.com/read/29754119/a-pilot-study-and-brief-overview-of-rehabilitation-via-virtual-environment-in-patients-suffering-from-dementia
#10
Th Fasilis, P Patrikelis, A Siatouni, A Alexoudi, A Veretzioti, L Zachou, S-St Gatzonis
Dementia is one of the increasing problems of modern societies. The immediate cure is not a possible solution, at least at the moment, but science has found a number of new ways to retard and under specific conditions to halt its development. A potential, and constantly evolving scientific field is the use of Computerized Cognitive Rehabilitation (CCR) and Virtual Environments (Vr.E). According to the existing literature, subjecting patients to various neuro-rehabilitative conditions within 3D virtual environments, allows them to obtain significant therapeutic benefits in which both transferability and durations over time are observed, in relation to the training period of the intervention...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29752249/virtual-antenatal-encounter-and-standardized-simulation-assessment-vanessa-pilot-study
#11
Patrick Motz, Megan Gray, Taylor Sawyer, Jennifer Kett, Douglas Danforth, Kellen Maicher, Rachel Umoren
BACKGROUND: Prenatal counseling at the limits of newborn viability involves sensitive interactions between neonatal providers and families. Empathetic discussions are currently learned through practice in times of high stress. Decision aids may help improve provider communication but have not been universally adopted. Virtual standardized patients are increasingly recognized as a modality for education, but prenatal counseling simulations have not been described. To be valuable as a tool, a virtual patient would need to accurately portray emotions and elicit a realistic response from the provider...
May 11, 2018: JMIR Serious Games
https://www.readbyqxmd.com/read/29748825/training-for-laparoscopic-pancreaticoduodenectomy
#12
REVIEW
Tamotsu Kuroki, Hikaru Fujioka
In recent years, laparoscopic procedures have developed rapidly, and the reports of laparoscopic pancreatic resection including laparoscopic pancreaticoduodenectomy (LPD) have increased in number. Although LPD is a complex procedure with high mortality, the training system for LPD remains unestablished. Ensuring patient safety is extremely important, even in challenging surgeries such a LPD. At present, several tools have been developed for surgical education to ensure patient safety preoperatively, such as video learning, virtual reality simulators, and cadaver training...
May 10, 2018: Surgery Today
https://www.readbyqxmd.com/read/29746560/clinical-virological-and-epidemiological-characterization-of-an-outbreak-of-testudinid-herpesvirus-3-in-a-chelonian-captive-breeding-facility-lessons-learned-and-first-evidence-of-tehv3-vertical-transmission
#13
Maria Luisa Marenzoni, Lorenzo Santoni, Andrea Felici, Carmen Maresca, Valentina Stefanetti, Monica Sforna, Maria Pia Franciosini, Patrizia Casagrande Proietti, Francesco Carlo Origgi
Testudinid herpesviruses (TeHVs) have a worldwide distribution among tortoises. However, information such as risk factors promoting the occurrence or the recrudescence of the associated disease and the mid-term sequelae of an outbreak comprising the extent and dynamic of the viral shedding have been only minimally investigated. Critical management information is also lacking or anecdotal. Furthermore, major aspects of the viral pathogenesis including the likelihood of vertical transmission of the virus are virtually unknown...
2018: PloS One
https://www.readbyqxmd.com/read/29746465/the-cybathlon-bci-race-successful-longitudinal-mutual-learning-with-two-tetraplegic-users
#14
Serafeim Perdikis, Luca Tonin, Sareh Saeedi, Christoph Schneider, José Del R Millán
This work aims at corroborating the importance and efficacy of mutual learning in motor imagery (MI) brain-computer interface (BCI) by leveraging the insights obtained through our participation in the BCI race of the Cybathlon event. We hypothesized that, contrary to the popular trend of focusing mostly on the machine learning aspects of MI BCI training, a comprehensive mutual learning methodology that reinstates the three learning pillars (at the machine, subject, and application level) as equally significant could lead to a BCI-user symbiotic system able to succeed in real-world scenarios such as the Cybathlon event...
May 2018: PLoS Biology
https://www.readbyqxmd.com/read/29742913/the-psychosocial-impact-of-nhs-digital-badges-on-a-school-aged-cohort
#15
Joanne H Alexander, Sarah Neill
Goal-oriented modalities of learning have long been used in educational settings to promote engagement and encourage a step-by-step approach to the acquisition of skills and knowledge. Historically, badges have been material, but in keeping with technological advancements there is a move towards encouraging greater digital engagement. Digital badges are today's version of the Scouts and Guides badge, a virtual non-material version, increasingly being utilized as a pedagogical resource in education and business settings...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29740974/a-machine-learning-approach-as-a-surrogate-of-finite-element-analysis-based-inverse-method-to-estimate-the-zero-pressure-geometry-of-human-thoracic-aorta
#16
Liang Liang, Minliang Liu, Caitlin Martin, Wei Sun
Advances in structural finite element analysis (FEA) and medical imaging have made it possible to investigate the in vivo biomechanics of human organs such as blood vessels, for which organ geometries at the zero-pressure level need to be recovered. Although FEA-based inverse methods are available for zero-pressure geometry estimation, these methods typically require iterative computation, which are time-consuming and may be not suitable for time-sensitive clinical applications. In this study, by using machine learning (ML) techniques, we developed a ML-model to estimate the zero-pressure geometry of human thoracic aorta by given two pressurized geometries of the same patient at two different blood pressure levels...
May 9, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29740365/the-use-of-virtual-reality-to-facilitate-mindfulness-skills-training-in-dialectical-behavioral-therapy-for-spinal-cord-injury-a-case-study
#17
Araceli Flores, Marsha M Linehan, S Rob Todd, Hunter G Hoffman
Introduction: Paralysis from a spinal cord injury (SCI) increases risk of psychological problems including suicide attempts, substance use disorder, negative emotions (e.g., anger), depression, anxiety, ASD/PTSD. Dialectical Behavioral Therapy® (DBT®) has been shown to be effective for treating similar psychological symptoms in non-SCI patient populations. The current study explored for the first time, the feasibility and clinical potential of using Immersive Virtual Reality (VR) enhanced DBT® Mindfulness skills training to help reduce psychological symptoms (negative emotions and anxiety, ASD/PTSD) of two patients with SCI...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29739837/nvertx-a-gene-expression-database-to-compare-embryogenesis-and-regeneration-in-the-sea-anemone-nematostella-vectensis
#18
Jacob F Warner, Vincent Guerlais, Aldine R Amiel, Hereroa Johnston, Karine Nedoncelle, Eric Röttinger
For over a century researchers have been comparing embryogenesis and regeneration hoping that lessons learned from embryonic development will unlock hidden regenerative potential. This problem has historically been a difficult one to investigate since the best regenerative model systems are poor embryonic models and vice versa. Recently however, this question has seen renewed interest as emerging models have allowed researchers to investigate these processes in the same organism. This interest has been further fueled by the advent of high-throughput transcriptomic analyses that provide virtual mountains of data...
May 8, 2018: Development
https://www.readbyqxmd.com/read/29737635/early-2018-update-board-members-preprints-and-special-issues
#19
EDITORIAL
David Peralta
Exciting changes: Editor David Peralta presents some changes to the ChemMedChem Editorial Board and International Advisory Board. Learn about the new board members in their biographies featured here. Also discussed are our new stance on preprint servers and our upcoming Special Issues, Virtual Issues, and exciting conferences the journal is supporting.
May 8, 2018: ChemMedChem
https://www.readbyqxmd.com/read/29735903/pharmaceutical-machine-learning-virtual-high-throughput-screens-identifying-promising-and-economical-small-molecule-inhibitors-of-complement-factor-c1s
#20
Jonathan J Chen, Lyndsey N Schmucker, Donald P Visco
When excessively activated, C1 is insufficiently regulated, which results in tissue damage. Such tissue damage causes the complement system to become further activated to remove the resulting tissue damage, and a vicious cycle of activation/tissue damage occurs. Current Food and Drug Administration approved treatments include supplemental recombinant C1 inhibitor, but these are extremely costly and a more economical solution is desired. In our work, we have utilized an existing data set of 136 compounds that have been previously tested for activity against C1...
May 7, 2018: Biomolecules
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