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https://www.readbyqxmd.com/read/28727421/shallow-representation-learning-via-kernel-pca-improves-qsar-modelability
#1
Stefano E Rensi, Russ B Altman
Linear models offer a robust, flexible, and computationally efficient set of tools for modeling quantitative structure activity relationships (QSAR), but have been eclipsed in performance by non-linear methods. Support vector machines (SVMs) and neural networks are currently among the most popular and accurate QSAR methods because they learn new representations of the data that greatly improve modelability. In this work we use shallow representation learning to improve the accuracy of L1 regularized logistic regression (LASSO) and meet the performance of Tanimoto SVM...
July 20, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28726502/spatial-reorientation-decline-in-aging-the-combination-of-geometry-and-landmarks
#2
Alessandro O Caffò, Antonella Lopez, Giuseppina Spano, Silvia Serino, Pietro Cipresso, Fabrizio Stasolla, Michelina Savino, Giulio E Lancioni, Giuseppe Riva, Andrea Bosco
OBJECTIVES: The study is focused on the assessment of reorientation skills in a sample of community-dwelling elderly people, manipulating landmarks and geometric (layout) information. METHOD: A neuropsychological assessment was administered to 286 elderly participants, divided into six groups (healthy controls, HC; four subgroups of participants with mild cognitive impairment, MCI; participants with probable dementia, Prob_D) and tested with the Virtual Reorientation Test (VReoT)...
July 20, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28724281/the-virtual-asthma-guideline-e-learning-program-learning-effectiveness-and-user-satisfaction
#3
Sung-Yoon Kang, Sae-Hoon Kim, Yong-Eun Kwon, Tae-Bum Kim, Hye-Kyung Park, Heung-Woo Park, Yoon-Seok Chang, Young-Koo Jee, Hee-Bom Moon, Kyung-Up Min, Sang-Heon Cho
Background/Aims: Effective educational tools are important for increasing adherence to asthma guidelines and clinical improvement of asthma patients. We developed a computer-based interactive education program for asthma guideline named the Virtual Learning Center for Asthma Management (VLCAM). We evaluated the usefulness of program in terms of its effects on user awareness of asthma guideline and level of satisfaction. Methods: Physicians-in-training at tertiary hospitals in Korea were enrolled in a cross-sectional questionnaire survey...
July 21, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28723986/the-contributions-of-digital-technologies-in-the-teaching-of-nursing-skills-an-integrative-review
#4
Maurício de Souza Silveira, Ana Luísa Petersen Cogo
Objective: To analyze the contributions of digital educational technologies used in teaching nursing skills. Method: Integrative literature review, search in five databases, from 2006 to 2015 combining the descriptors 'education, nursing', 'educational technology', 'computer-assisted instruction' or related terms in English. Results: Sample of 30 articles grouped in the thematic categories 'technology in the simulation with manikin', 'incentive to learning' and 'teaching of nursing skills'...
July 13, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28720915/evaluation-of-the-use-of-a-virtual-patient-on-student-competence-and-confidence-in-performing-simulated-clinic-visits
#5
Catherine A Taglieri, Steven J Crosby, Kristin Zimmerman, Tulip Schneider, Dhiren K Patel
Objective. To assess the effect of incorporating virtual patient activities in a pharmacy skills lab on student competence and confidence when conducting real-time comprehensive clinic visits with mock patients. Methods. Students were randomly assigned to a control or intervention group. The control group completed the clinic visit prior to completing virtual patient activities. The intervention group completed the virtual patient activities prior to the clinic visit. Student proficiency was evaluated in the mock lab...
June 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28719062/immersive-virtual-reality-as-a-teaching-tool-for-neuroanatomy
#6
Katelyn Stepan, Joshua Zeiger, Stephanie Hanchuk, Anthony Del Signore, Raj Shrivastava, Satish Govindaraj, Alfred Iloreta
BACKGROUND: Three-dimensional (3D) computer modeling and interactive virtual reality (VR) simulation are validated teaching techniques used throughout medical disciplines. Little objective data exists supporting its use in teaching clinical anatomy. Learner motivation is thought to limit the rate of utilization of such novel technologies. The purpose of this study is to evaluate the effectiveness, satisfaction, and motivation associated with immersive VR simulation in teaching medical students neuroanatomy...
July 18, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28716337/physical-models-and-virtual-reality-simulators-in-otolaryngology
#7
REVIEW
Luv Javia, Maya G Sardesai
The increasing role of simulation in the medical education of future otolaryngologists has followed suit with other surgical disciplines. Simulators make it possible for the resident to explore and learn in a safe and less stressful environment. The various subspecialties in otolaryngology use physical simulators and virtual-reality simulators. Although physical simulators allow the operator to make direct contact with its components, virtual-reality simulators allow the operator to interact with an environment that is computer generated...
July 14, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28711211/advanced-tissue-characterization-and-texture-analysis-using-dual-energy-computed-tomography-horizons-and-emerging-applications
#8
REVIEW
Reza Forghani, Ashok Srinivasan, Behzad Forghani
In the last article of this issue, advanced analysis capabilities of DECT is reviewed, including spectral Hounsfield unit attenuation curves, virtual monochromatic images, material decomposition maps, tissue effective Z determination, and other advanced post-processing DECT tools, followed by different methods of analysis of the attenuation curves generated using DECT. The article concludes with exciting future horizons and potential applications, such as the use of the rich quantitative data in dual energy CT scans for texture or radiomic analysis and the use of machine learning methods for generation of prediction models using spectral data...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28710000/the-perisylvian-language-network-and-language-analytical-abilities
#9
Olga Kepinska, Egbert A J F Lakke, Eleanor M Dutton, Johanneke Caspers, Niels O Schiller
Aiming at exploring the brain's structural organisation underlying successful second language learning, we investigate the anatomy of the perisylvian language network in a group of healthy adults, consisting of participants with high and average language analytical abilities. Utilising deterministic tractography, six tracts per participant (left and right long direct segment, left and right indirect anterior segment and left and right indirect posterior segment) were virtually dissected and measurements pertaining to their microstructural organisation were collected...
July 11, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28708548/predicting-locations-of-high-risk-plaques-in-coronary-arteries-in-patients-receiving-statin-therapy
#10
Ling Zhang, Andreas Wahle, Zhi Chen, John J Lopez, Tomas Kovarnik, Milan Sonka
Features of high-risk coronary artery plaques prone to major adverse cardiac events (MACE) were identified by intravascular ultrasound (IVUS) virtual histology (VH). These plaque features are: Thin-cap fibroatheroma (TCFA), plaque burden PB≥70%, or minimal luminal area MLA≤4mm². Identification of arterial locations likely to later develop such high-risk plaques may help prevent MACE. We report a machine learning method for prediction of future high-risk coronary plaque locations and types in patients under statin therapy...
July 11, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28705738/identification-of-novel-potential-scaffold-for-class-i-hdacs-inhibition-an-in-silico-protocol-based-on-virtual-screening-molecular-dynamics-mathematical-analysis-and-machine-learning
#11
Cong Fan, Yanxin Huang
Histone deacetylases (HDACs) family has been widely reported as an important class of enzyme targets for cancer therapy. Much effort has been made in discovery of novel scaffolds for HDACs inhibition besides existing hydroxamic acids, cyclic peptides, benzamides, and short-chain fatty acids. Herein we set up an in-silico protocol which not only could detect potential Zn(2+) chelation bonds but also still adopted non-bonded model to be effective in discovery of Class I HDACs inhibitors, with little human's subjective visual judgment involved...
July 10, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28705170/can-lokomat-therapy-with-children-and-adolescents-be-improved-an-adaptive-clinical-pilot-trial-comparing-guidance-force-path-control-and-freed
#12
Tabea Aurich-Schuler, Fabienne Grob, Hubertus J A van Hedel, Rob Labruyère
BACKGROUND: Robot-assisted gait therapy is increasingly being used in pediatric neurorehabilitation to complement conventional physical therapy. The robotic device applied in this study, the Lokomat (Hocoma AG, Switzerland), uses a position control mode (Guidance Force), where exact positions of the knee and hip joints throughout the gait cycle are stipulated. Such a mode has two disadvantages: Movement variability is restricted, and patients tend to walk passively. Kinematic variability and active participation, however, are crucial for motor learning...
July 14, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28704286/the-effect-of-force-feedback-in-a-virtual-learning-environment-on-the-performance-and-satisfaction-of-dental-students
#13
Ilse R de Boer, Maxim D Lagerweij, Merlijn W de Vries, Paul R Wesselink, Johanna M Vervoorn
INTRODUCTION: This study investigated the effect of force feedback (FFB) on student performance in a virtual learning environment (VLE) using the Simodont dental trainer (Moog, Nieuw-Vennep, the Netherlands) and evaluated the students' satisfaction with and without FFB. METHODS: The Simodont dental trainer, which was used as a VLE, was randomly assigned to 101 first-year dental students with no previous experience in cutting a tooth or working in a VLE with FFB...
April 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28704187/striving-for-better-medical-education-the-simulation-approach
#14
REVIEW
Boris E Sakakushev, Blagoi I Marinov, Penka P Stefanova, Stefan St Kostianev, Evangelos K Georgiou
Medical simulation is a rapidly expanding area within medical education due to advances in technology, significant reduction in training hours and increased procedural complexity. Simulation training aims to enhance patient safety through improved technical competency and eliminating human factors in a risk free environment. It is particularly applicable to a practical, procedure-orientated specialties. Simulation can be useful for novice trainees, experienced clinicians (e.g. for revalidation) and team building...
June 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28701199/effectiveness-of-distance-learning-strategies-for-continuing-professional-development-cpd-for-rural-allied-health-practitioners-a-systematic-review
#15
Angela Berndt, Carolyn M Murray, Kate Kennedy, Mandy J Stanley, Susan Gilbert-Hunt
BACKGROUND: Allied health professionals working in rural areas face unique challenges, often with limited access to resources. Accessing continuing professional development is one of those challenges and is related to retention of workforce. Effectiveness of distance learning strategies for continuing professional development in rural allied healthcare workers has not been evaluated. METHODS: We searched 17 databases and the grey literature up to September 2016 following the PRISMA guidelines...
July 12, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28697057/computerized-virtual-reality-simulation-in-preclinical-dentistry-can-a-computerized-simulator-replace-the-conventional-phantom-heads-and-human-instruction
#16
Anastasios Plessas
In preclinical dental education, the acquisition of clinical, technical skills, and the transfer of these skills to the clinic are paramount. Phantom heads provide an efficient way to teach preclinical students dental procedures safely while increasing their dexterity skills considerably. Modern computerized phantom head training units incorporate features of virtual reality technology and the ability to offer concurrent augmented feedback. The aims of this review were to examine and evaluate the dental literature for evidence supporting their use and to discuss the role of augmented feedback versus the facilitator's instruction...
July 10, 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28692230/-virtual-reality-simulation-training-in-gynecology-review-and-perspectives
#17
Dominique Ricard-Gauthier, Silvia Popescu, Naida Benmohamed, Patrick Petignat, Jean Dubuisson
Laparoscopic simulation has rapidly become an important tool for learning and acquiring technical skills in surgery. It is based on two different complementary pedagogic tools : the box model trainer and the virtual reality simulator. The virtual reality simulator has shown its efficiency by improving surgical skills, decreasing operating time, improving economy of movements and improving self-confidence. The main objective of this tool is the opportunity to easily organize a regular, structured and uniformed training program enabling an automated individualized feedback...
October 26, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28691756/surgical-specimen-handover-from-the-operating-theatre-to-laboratory-can-we-improve-patient-safety-by-learning-from-aviation-and-other-high-risk-organisations
#18
Peter A Brennan, Marieke T Brands, Lucy Caldwell, Felipe Paiva Fonseca, Nic Turley, Susie Foley, Siavash Rahimi
Essential communication between healthcare staff is considered one of the key requirements for both safety and quality care when patients are handed over from one clinical area to other. This is particularly important in environments such as the operating theatre and intensive care where mistakes can be devastating. Healthcare has learned from other high-risk organisations (HRO) such aviation where the use of checklists and human factors awareness has virtually eliminated human error and mistakes. To our knowledge, little has been published around ways to improve pathology specimen handover following surgery, with pathology request forms often conveying the bare minimum of information to assist the laboratory staff...
July 10, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28691267/the-use-of-virtual-patient-scenarios-as-a-vehicle-for-teaching-professionalism
#19
H F Marei, M M Al-Eraky, N N Almasoud, J Donkers, J J G Van Merrienboer
OBJECTIVES: This study aimed to measure students' perceptions of virtual patient scenarios (VPs) for developing ethical reasoning skills and to explore features in VP design that are necessary to promote professionalism. METHODS: Sixty-five dental students participated in learning sessions that involved collaborative practice with five VPs (four high fidelity and one low fidelity), followed by reflection sessions. Students' perceptions towards the use of VPs in developing ethical reasoning skills were assessed using a questionnaire that involved 10 closed and three open-ended questions...
July 10, 2017: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/28690437/the-use-of-modular-electronic-neuron-simulators-for-neural-circuit-construction-produces-learning-gains-in-an-undergraduate-anatomy-and-physiology-course
#20
Andrew Petto, Zachary Fredin, Joseph Burdo
During the spring of 2016 at the University of Wisconsin-Milwaukee, we implemented a novel educational technology designed to teach undergraduates about the nervous system while allowing them to physically construct their own neural circuits. Modular, electronic neuron simulators called NeuroBytes were used by the students in BIOSCI202 Anatomy and Physiology I, a four-credit course consisting of three hours per week each of lecture and laboratory time. 162 students participated in the laboratory sessions that covered reflexes; 83 in the experimental sections used the NeuroBytes to build a model of the patellar tendon reflex, while 79 in the control sections participated in alternate reflex curricula...
2017: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
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