keyword
https://read.qxmd.com/read/38470573/ctnet-contrastive-transformer-network-for-polyp-segmentation
#21
JOURNAL ARTICLE
Bin Xiao, Jinwu Hu, Weisheng Li, Chi-Man Pun, Xiuli Bi
Segmenting polyps from colonoscopy images is very important in clinical practice since it provides valuable information for colorectal cancer. However, polyp segmentation remains a challenging task as polyps have camouflage properties and vary greatly in size. Although many polyp segmentation methods have been recently proposed and produced remarkable results, most of them cannot yield stable results due to the lack of features with distinguishing properties and those with high-level semantic details. Therefore, we proposed a novel polyp segmentation framework called contrastive Transformer network (CTNet), with three key components of contrastive Transformer backbone, self-multiscale interaction module (SMIM), and collection information module (CIM), which has excellent learning and generalization abilities...
March 12, 2024: IEEE Transactions on Cybernetics
https://read.qxmd.com/read/38469604/the-prognostic-importance-of-cancer-stem-cells-in-colorectal-polyps
#22
JOURNAL ARTICLE
Aynur Safiyeva, Nuru Bayramov, Mustafa Cihat Avunduk
BACKGROUND: This purpose aims to investigate the usefulness of CD133, a stem cell marker, for the prognosis of colon polyps. This study aimed to assess the adenomatous polyps that have an essential role in the development of colorectal cancer. The risk of colorectal carcinogenesis can be reduced by polypectomy and close medical supervision of the patients with adenomatous polyps. The prominence of stem cells in carcinoma development is also a recognized verdict. It must be noted that stem cell evaluation in adenomatous polyps may provide information about carcinoma development...
2024: Annali Italiani di Chirurgia
https://read.qxmd.com/read/38465713/recurrence-and-carcinogenetic-rates-of-colorectal-polyps
#23
JOURNAL ARTICLE
Marilena Stoian, Gabriel Becheanu, Irina Balescu, Mihai Eftimie, Sorin Petrea, Camelia Diaconu, Bogdan Gaspar, Lucian Pop, Valentin Varlas, Adrian Hasegan, Cristina Martac, Ciprian Bolca, Cezar Stroescu, Anca Zgura, Nicolae Bacalbasa
AIM: to determin the recurrence rate of benign recto-colonic polyps in a 5-year interval, and compare the development rate of intrapolypoid carcinomatous lesions in polypectomized versus nonpolypectomized subjects. MATERIAL AND METHOD: a group of 77 patients diagnosed with recto-colonic polypoid lesions during the period 2014-2019 underwent colonoscopy at the time of study initiation and then annually during a five-year interval. Results: The recurrence rate of polyps increased annually from 5 to 12...
February 2024: Chirurgia
https://read.qxmd.com/read/38465396/screening-for-colorectal-cancer-by-full-colonoscopy-in-first-degree-relatives-of-colorectal-cancer-patients-a-multicentric-study-by-the-italian-league-for-the-fight-against-cancer
#24
JOURNAL ARTICLE
Giacomo Diedenhofen, Augusto Morgia, Nicola Sinnona, Alberto Pacchiarotti, Anna Fiaschetti, Vito Forte, Mauro Tosoni, Fabrizio Liberati, Sandro Boschetto, Enrico Zepponi, Pietro Marogna, Alessandra Manca, Marco Bisail, Annarita Vestri, Alessandro Rossi
BACKGROUND: Colorectal cancer currently presents the third-highest incidence of cancers worldwide, making secondary prevention through screening programs for colorectal cancer, usually by Fecal Occult Blood Testing, an essential preventive medicine intervention. First-degree relatives of colorectal cancer patients are a particularly at-risk group, with indications to consider direct screening by full colonoscopy. Colonoscopy is considered the gold standard for diagnosing colorectal cancer, as it has high sensitivity and specificity, and is both a diagnostic and therapeutic tool...
March 7, 2024: Annali di Igiene: Medicina Preventiva e di Comunità
https://read.qxmd.com/read/38464818/association-between-triglyceride-glucose-index-and-colorectal-polyps-a-retrospective-cross-sectional-study
#25
JOURNAL ARTICLE
Ya-Jie Teng, Ying-Xue Yang, Jing-Jing Yang, Qiu-Yan Lu, Jia-Yi Shi, Jian-Hao Xu, Jie Bao, Qing-Hua Wang
BACKGROUND: Colorectal polyps (CPs) are frequently occurring abnormal growths in the colorectum, and are a primary precursor of colorectal cancer (CRC). The triglyceride-glucose (TyG) index is a novel marker that assesses metabolic health and insulin resistance, and has been linked to gastrointestinal cancers. AIM: To investigate the potential association between the TyG index and CPs, as the relation between them has not been documented. METHODS: A total of 2537 persons undergoing a routine health physical examination and colonoscopy at The First People's Hospital of Kunshan, Jiangsu Province, China, between January 2020 and December 2022 were included in this retrospective cross-sectional study...
February 16, 2024: World Journal of Gastrointestinal Endoscopy
https://read.qxmd.com/read/38461798/uptake-and-detection-rate-of-colorectal-cancer-screening-with-colonoscopy-in-china-a-population-based-prospective-cohort-study
#26
JOURNAL ARTICLE
Zhikai Yu, Bibo Li, Shenglin Zhao, Jia Du, Yan Zhang, Xiu Liu, Qing Guo, Hong Zhou, Mei He
BACKGROUND: Colorectal cancer is the leading cause of cancer-related death worldwide. Colonoscopy is widely used as a screening test for detecting colorectal cancer in many countries. However, there is little evidence regarding the uptake and diagnostic yields of colonoscopy in population-based screening programs in countries with limited medical resources. OBJECTIVE: We reported the uptake of colonoscopy and the detection of colorectal lesions and explored related factors based on a colorectal cancer screening program in China...
February 20, 2024: International Journal of Nursing Studies
https://read.qxmd.com/read/38461207/slc26a9-promotes-colorectal-tumorigenesis-by-modulating-wnt-%C3%AE-catenin-signaling
#27
JOURNAL ARTICLE
Minglin Zhang, Zhiyuan Ma, Zhiqiang Yi, Hu Wang, Jiaxing Zhu, Guorong Wen, Hai Jin, Jiaxing An, Zilin Deng, Biguang Tuo, Taolang Li, Xuemei Liu
Solute carrier family 26 member 9 (SLC26A9) is a member of the Slc26a family of multifunctional anion transporters that functions as a Cl- channel in parietal cells during acid secretion. We explored the role of SLC26A9 in colorectal cancer (CRC) and its related mechanisms through clinical samples from CRC patients, CRC cell lines and mouse models. We observed that SLC26A9 was expressed at low levels in the cytoplasm of adjacent tissues, polyps and adenomas but was significantly increased in colorectal adenocarcinoma...
March 9, 2024: Cell Death Discovery
https://read.qxmd.com/read/38459471/efficacy-and-safety-of-esketamine-combined-with-propofol-for-curative-endoscopic-resection-in-colorectum-a-prospective-randomized-controlled-trial
#28
JOURNAL ARTICLE
Yimei Ma, Jiali Wang, Yuying Yang, Minmin Yao
BACKGROUND: Curative endoscopic resection is widely used to treat colonic polyps and early stage cancers. The anesthetic strategy commonly involves the use of propofol combined with a small dose of opioids for sedation. Adverse respiratory or cardiovascular events such as hypotension often occur when attempting to achieve the necessary level of sedation. Several studies have suggested its advantages owing to the anesthetic, analgesic, and sympathomimetic properties of esketamine. However, there are no reports on curative colorectal endoscopic resection...
March 9, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38454673/simultaneous-segmentation-and-classification-of-colon-cancer-polyp-images-using-a-dual-branch-multi-task-learning-network
#29
JOURNAL ARTICLE
Chenqian Li, Jun Liu, Jinshan Tang
Accurate classification and segmentation of polyps are two important tasks in the diagnosis and treatment of colorectal cancers. Existing models perform segmentation and classification separately and do not fully make use of the correlation between the two tasks. Furthermore, polyps exhibit random regions and varying shapes and sizes, and they often share similar boundaries and backgrounds. However, existing models fail to consider these factors and thus are not robust because of their inherent limitations...
January 8, 2024: Mathematical Biosciences and Engineering: MBE
https://read.qxmd.com/read/38451998/underwater-versus-conventional-endoscopic-mucosal-resection-for-%C3%A2-10-mm-sessile-or-flat-colorectal-polyps-a-systematic-review-and-meta-analysis
#30
JOURNAL ARTICLE
Xue Wang, Yue Wang, Xueyan Cao, Chunmei Zhang, Lin Miao
BACKGROUND AND AIM: Underwater endoscopic mucosal resection (UEMR) has been an emerging substitute for conventional EMR (CEMR). This systematic review and meta-analysis aimed at comparing the efficiency and safety of the two techniques for removing ≥10 mm sessile or flat colorectal polyps. METHODS: PubMed, Cochrane Library and Embase databases were searched up to February 2023 to identify eligible studies that compared the outcomes of UEMR and CEMR. This meta-analysis was conducted on the en bloc resection rate, R0 resection rate, complete resection rate, procedure time, adverse events rate and recurrence rate...
2024: PloS One
https://read.qxmd.com/read/38445134/effectiveness-of-dual-focus-magnification-on-confidence-levels-in-optical-diagnosis-of-small-colorectal-polyps
#31
JOURNAL ARTICLE
Tien M Huynh, Quang D Le, Nhan Q Le, Huy M Le, Duc T Quach
Background and objectives Achieving accurate real-time optical diagnoses of colorectal polyps with high-confidence predictions is crucial for appropriate decision-making in daily practice. The dual-focus (DF) magnification mode helps endoscopists scrutinize subtle features of polyp surfaces and vessel patterns. This prospective study aimed to evaluate the impact of DF imaging on enhancing the rate of high-confidence narrow-band imaging (NBI)-based optical diagnosis. Methods Consecutive adult patients who underwent colonoscopy and had small colorectal polyps (<10 mm) were enrolled between September 2022 and May 2023...
February 2024: Curēus
https://read.qxmd.com/read/38444677/retrospective-cohort-study-investigating-association-between-precancerous-gastric-lesions-and-colorectal-neoplasm-risk
#32
JOURNAL ARTICLE
Hui Pan, Yu-Long Zhang, Chao-Ying Fang, Yu-Dai Chen, Li-Ping He, Xiao-Ling Zheng, Xiaowen Li
BACKGROUND: Colorectal cancer (CRC) is considered the most prevalent synchronous malignancy in patients with gastric cancer. This large retrospective study aims to clarify correlations between gastric histopathology stages and risks of specific colorectal neoplasms, to optimize screening and reduce preventable CRC. METHODS: Clinical data of 36,708 patients undergoing gastroscopy and colonoscopy from 2005-2022 were retrospectively analyzed. Correlations between gastric and colorectal histopathology were assessed by multivariate analysis...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38435637/methods-for-identification-of-the-opportunistic-gut-mycobiome-from-colorectal-adenocarcinoma-biopsy-tissues
#33
JOURNAL ARTICLE
Aisyah Yunus, Norfilza Mohd Mokhtar, Raja Affendi Raja Ali, Siti Maryam Ahmad Kendong, Hajar Fauzan Ahmad
Colorectal cancer poses a significant threat to global health, necessitating the development of effective early detection techniques. However, the potential of the fungal microbiome as a putative biomarker for the detection of colorectal adenocarcinoma has not been extensively explored. We analyzed the viability of implementing the fungal mycobiome for this purpose. Biopsies were collected from cancer and polyp patients. The total genomic DNA was extracted from the biopsy samples by utilizing a comprehensive kit to ensure optimal microbial DNA recovery...
June 2024: MethodsX
https://read.qxmd.com/read/38433553/novel-method-of-image-analysis-that-combines-radon-and-fourier-image-transformations-for-the-purpose-of-differentiating-between-malignant-and-benign-colonic-biopsies
#34
JOURNAL ARTICLE
Chen Faibis, Edmond Sabo, Salam Mazareb, Geula Klorin
Colorectal cancer is the third most common type of cancer. It develops slowly as a polyp that can turn into a cancerous tumor. This study aimed to develop a decision-making algorithm of microscopic images using texture analysis that is orientation free, to be used for automated classification of normal and neoplastic (malignant or premalignant) colonic biopsies. Forty-nine colonic adenocarcinomas, 41 adenomas and a control group of adjacent normal colonic mucosa were included in the texture analysis. Radon transform followed by the Fast Fourier transform were applied to the images...
March 3, 2024: Microscopy Research and Technique
https://read.qxmd.com/read/38433121/adenoma-characteristics-in-the-english-bowel-cancer-screening-programme
#35
JOURNAL ARTICLE
Debasis Majumdar, Roisin Bevan, Mahmoud Essam, Claire Nickerson, Pali Hungin, Mike Bramble, Matthew D Rutter
AIM: The English Bowel Cancer Screening Programme detects colorectal cancers and premalignant polyps in a faecal occult blood test-positive population. The aim of this work is to describe the detection rates and characteristics of adenomas within the programme, identify predictive factors influencing the presence or absence of carcinoma within adenomas and identify the factors predicting the presence of advanced colonic neoplasia in different colon segments. METHOD: The Bowel Cancer Screening System was retrospectively searched for polyps detected during colonoscopies between June 2006 and June 2012, at which time a guaiac test was being used...
March 3, 2024: Colorectal Disease
https://read.qxmd.com/read/38429684/efficient-organized-colorectal-cancer-screening-in-shenzhen-a-microsimulation-modelling-study
#36
JOURNAL ARTICLE
Minmin Zhu, Xuan Zhong, Tong Liao, Xiaolin Peng, Lin Lei, Ji Peng, Yong Cao
BACKGROUND: Colorectal cancer (CRC) is a global health issue with noticeably high incidence and mortality. Microsimulation models offer a time-efficient method to dynamically analyze multiple screening strategies. The study aimed to identify the efficient organized CRC screening strategies for Shenzhen City. METHODS: A microsimulation model named CMOST was employed to simulate CRC screening among 1 million people without migration in Shenzhen, with two CRC developing pathways and real-world participation rates...
March 1, 2024: BMC Public Health
https://read.qxmd.com/read/38429655/downregulation-of-smoc1-is-associated-with-progression-of-colorectal-traditional-serrated-adenomas
#37
JOURNAL ARTICLE
Hironori Aoki, Akira Takasawa, Eiichiro Yamamoto, Takeshi Niinuma, Hiro-O Yamano, Taku Harada, Toshiyuki Kubo, Akira Yorozu, Hiroshi Kitajima, Kazuya Ishiguro, Masahiro Kai, Akio Katanuma, Toshiya Shinohara, Hiroshi Nakase, Tamotsu Sugai, Makoto Osanai, Hiromu Suzuki
BACKGROUND: Aberrant DNA methylation is prevalent in colorectal serrated lesions. We previously reported that the CpG island of SMOC1 is frequently methylated in traditional serrated adenomas (TSAs) and colorectal cancers (CRCs) but is rarely methylated in sessile serrated lesions (SSLs). In the present study, we aimed to further characterize the expression of SMOC1 in early colorectal lesions. METHODS: SMOC1 expression was analyzed immunohistochemically in a series of colorectal tumors (n = 199) and adjacent normal colonic tissues (n = 112)...
March 1, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38422398/histopathological-evaluation-of-pouch-neoplasia-in-inflammatory-bowel-diseases-and-familial-adenomatous-polyposis
#38
JOURNAL ARTICLE
Huaibin Mabel Ko
BACKGROUND: Ileal pouch-anal anastomosis is often required for patients with ulcerative colitis or familial adenomatous polyposis after colectomy. This procedure reduces but does not completely eliminate the risk of neoplasia. OBJECTIVE: This study focuses on the histopathology of neoplasia in the ileal pouch, rectal cuff, and anal transition zone. DATA SOURCES: We performed a Medline search for English language studies published between 1981 and 2022 using the PubMed search engine...
February 29, 2024: Diseases of the Colon and Rectum
https://read.qxmd.com/read/38418684/cold-snare-polypectomy-with-or-without-submucosal-injection-for-endoscopic-resection-of-colorectal-polyps-a-meta-analysis-of-randomized-controlled-trials
#39
JOURNAL ARTICLE
Xiu-He Lv, Tong Liu, Zi-Jing Wang, Tao Gan, Jin-Lin Yang
BACKGROUND AND AIMS: The impact of submucosal injection during cold snare polypectomy (CSP) remains uncertain. We conducted an evidence-based comparison of conventional CSP (C-CSP) and CSP with submucosal injection (SI-CSP) for colorectal polyp resection. METHODS: PubMed, Embase, and the Cochrane Library databases were searched for randomized controlled trials (RCTs) comparing C-CSP with SI-CSP. Major outcomes included the rates of complete resection, en bloc resection, polyp retrieval, and adverse events, as well as the duration of polypectomy...
February 28, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38418285/the-impact-of-endocuff-assisted-colonoscopy-on-the-polyp-detection-rate-a-cross-over-randomized-back-to-back-study
#40
JOURNAL ARTICLE
Mohammed Sherif Naguib, Ahmed Khairy, Hany Shehab, Hazem Abosheaishaa, Abdel Meguid Kassem
BACKGROUND AND STUDY AIMS: Colorectal cancer (CRC) is one of the most common cancers worldwide, and most CRCs develop from polyps with malignant potential. We aimed to study the difference in polyp detection rate between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopy (SC). PATIENTS AND METHODS: This study was conducted at Cairo University Hospitals on patients referred for screening or diagnostic colonoscopy from July 2018 to August 2020. All included patients underwent back-to-back standard colonoscopy (SC) and ENDOCUFF VISION-assisted colonoscopies (EAC)...
February 27, 2024: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
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