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https://www.readbyqxmd.com/read/28730368/safety-of-cold-polypectomy-for-small-colorectal-neoplastic-lesions-a-prospective-cohort-study-in-japan
#1
Yuichi Shimodate, Motowo Mizuno, Rio Takezawa, Mami Kobayashi, Tatsuhiro Yamazaki, Akira Doi, Naoyuki Nishimura, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto
BACKGROUND: Cold polypectomy has been widely accepted for removal of small colorectal polyps. However, no large-scale prospective study exists as for its safety in Japan. We investigated this issue in this single-center, prospective cohort study in a total of 1198 colorectal polyps resected with cold polypectomy. PATIENTS AND METHODS: Four hundred and seventy-four patients who underwent cold polypectomy for colorectal neoplastic lesions less than 10-mm diameter between September 2014 and October 2016 were enrolled...
July 20, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28728314/local-recurrence-and-its-risk-factor-after-incomplete-resection-of-colorectal-advanced-adenomas-a-single-center-retrospective-study
#2
Dae Myung Oh, Jae Kwang Lee, Hyunsoo Kim, Chang Keun Park, Jae Kwon Jung, Dae Jin Kim, Yun Jin Chung, Tae Hoon Kim, Myung Il Park, Jong Pil Park
Background/Aims: Colonoscopy can detect precancerous lesions, which can subsequently be removed and reduce incidences of and mortality from colorectal cancer (CRC). However, recently published data have highlighted a significant rate of CRC in patients who previously underwent colonoscopy. Among many reasons, incomplete resection has been considered as a significant contributor. However, to date, there have only been a few studies regarding incompletely resected polyps, especially advanced colorectal adenoma (ACA)...
July 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28725959/linked-color-imaging-improves-the-visibility-of-various-featured-colorectal-polyps-in-an-endoscopist-s-visibility-and-color-difference-value
#3
Naohisa Yoshida, Yuji Naito, Ritsu Yasuda, Takaaki Murakami, Ryohei Hirose, Kiyoshi Ogiso, Yutaka Inada, Osamu Dohi, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Hideyuki Konishi, Rafiz Abdul Rani, Mitsuo Kishimoto, Eiichi Konishi, Yoshito Itoh
PURPOSE: Linked color imaging (LCI) by laser endoscopy is a novel narrow band light observation. In this study, we analyzed the efficacy of LCI for improving the various featured colorectal polyp's visibility utilizing a subjective endoscopist's visibility scoring and objective color difference (CD) value. METHODS: We retrospectively reviewed two pictures both with white light (WL) and LCI for 54 consecutive neoplastic polyps 2-20 mm in size. All pictures were evaluated by four endoscopists according to a published polyp visibility score from four (excellent visibility) to one (poor visibility)...
July 19, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28721979/histological-outcomes-between-hot-and-cold-snare-polypectomy-for-small-colorectal-polyps
#4
Toshiki Yamamoto, Sho Suzuki, Chika Kusano, Kyoko Yakabe, Maho Iwamoto, Hisatomo Ikehara, Takuji Gotoda, Mitsuhiko Moriyama
BACKGROUND/AIM: To compare the complete resection rate of hot and cold snare polypectomy for small colorectal polyps. PATIENTS AND METHODS: We retrospectively reviewed the medical records of 233 consecutive patients with 461 colorectal polyps up to 10 mm in diameter that were treated by hot or cold snare polypectomy between April 2014 and August 2016. Lesions treated by hot snare polypectomy (n = 137) and cold snare polypectomy (n = 324) were compared. The histological complete resection rates were evaluated between the two groups...
July 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28717246/estimating-utility-weights-and-quality-adjusted-life-year-loss-for-colorectal-cancer-related-health-states-in-korea
#5
Jin Yong Lee, Minsu Ock, Min-Woo Jo, Woo-Seung Son, Hyeon-Jeong Lee, Seon-Ha Kim, Hyun Joo Kim, Jong Lyul Lee
We aimed to assess utility weight of health states associated with colorectal cancer (CRC) that reflect the societal preference of the Korean population and to estimate the quality-adjusted life year (QALY) loss with CRC. We recruited 607 individuals from the Korean population; they were surveyed via face-to-face computer-assisted interviews. The participants evaluated each CRC-associated health state using standard gamble. Utility weight for each health state was calculated as the possibility of full health restoration...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28710436/epithelial-derived-il-33-promotes-intestinal-tumorigenesis-in-apc-min-mice
#6
Zhengxiang He, Lili Chen, Fabricio O Souto, Claudia Canasto-Chibuque, Gerold Bongers, Madhura Deshpande, Noam Harpaz, Huaibin M Ko, Kevin Kelley, Glaucia C Furtado, Sergio A Lira
Increased expression of Interleukin (IL)-33 has been detected in intestinal samples of patients with ulcerative colitis, a condition associated with increased risk for colon cancer, but its role in the development of colorectal cancer has yet to be fully examined. Here, we investigated the role of epithelial expressed IL-33 during development of intestinal tumors. IL-33 expression was detected in epithelial cells in colorectal cancer specimens and in the Apc (Min/+) mice. To better understand the role of epithelial-derived IL-33 in the intestinal tumorigenesis, we generated transgenic mice expressing IL-33 in intestinal epithelial cells (V33 mice)...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28705174/extensive-colorectal-lymphomatous-polyposis-complicated-by-acute-intestinal-obstruction-a-case-report
#7
Jaques Waisberg, Amanda do Val Anderi, Pedro Augusto Soffner Cardoso, José Henrique Miranda Borducchi, Demetrius Eduardo Germini, Maria Isete Fares Franco, Cidia Vasconcellos
BACKGROUND: Multiple lymphomatous polyposis is a rare type of gastrointestinal lymphoma that extensively infiltrates the intestine. Multiple lymphomatous polyposis originates from the mantle zone of the lymphoma follicle and is considered to be a mantle cell lymphoma, which is a relatively aggressive type of B-cell non-Hodgkin's lymphoma. We report an unusual case of a patient with multiple lymphomatous polyposis with extensive colorectal involvement and acute intestinal obstruction, an atypical complication of this rare disease...
July 13, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28702775/quality-indicators-in-colonoscopy
#8
REVIEW
Kjetil Garborg, Thomas de Lange, Michael Bretthauer
Colonoscopy is one of the most commonly performed endoscopic procedures. It is the gold standard examination for work-up of colonic symptoms, for follow-up of positive colorectal cancer screening tests and for detection and removal of neoplastic polyps. Colonoscopy is a complex and invasive procedure with a potential not only for colorectal cancer prevention, but also for serious complications. Numerous factors may affect the balance of benefit versus harm of colonoscopy, including the performance of the endoscopist...
July 12, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28702134/evaluating-the-frequency-of-mlh-1-loss-in-serrated-polyps-of-colon-a-single-center-study-from-southern-iran
#9
Bita Geramizadeh, Nooshin Dindar, Samirasadat Hasheminasab, Tahere Haeidari
AIM: Evaluation of the role of MLH-1 loss in serrated polyps of colon in a population of South of Iran. BACKGROUND: There has been extensive change in classification and pathogenesis of serrated polyps of the colon during the last 10 years. The new classification is mostly based on the knowledge of the molecular pathogenesis and the rate of progression to colorectal cancer in these types of polyps. One of the most common and early lesions in molecular pathogenesis of serrated colorectal cancer is loss of MLH-1...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702131/distribution-pattern-of-colorectal-diseases-based-on-2300-total-colonoscopies
#10
Yousef Bafandeh, Fereshteh Yazdanpanah
AIM: We conducted a cross-sectional study to estimate the prevalence of CRD in our area in East Azerbaijan, Iran. BACKGROUND: Colorectal diseases (CRD) include a broad spectrum that varies from benign lesions to malignant and cancerous masses. CRD can be investigated by colonoscopy. Some of these diseases are highly preventable with timely screening and appropriate planning by the healthcare system. METHODS: This is a hospital-based, cross-sectional study by the Gastroenterology Department on patients who underwent colonoscopy between June 2013 and March 2015 in outpatient clinics at private Shahriyar medical center and Imam Reza University Hospital in Tabriz, East Azerbaijan province, Iran...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28698863/evaluation-of-the-expression-of-the-inhibitor-of-apoptosis-protein-family-and-human-telomerase-reverse-transcriptase-in-patients-with-advanced-colorectal-adenoma
#11
Joon Young Choi, Hyuk Yoon, Gyeongjae Na, Yoon Jin Choi, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
BACKGROUND: It has been reported that the expression of the inhibitor of apoptosis protein (IAP) family increases in patients with colon cancer. We evaluated the expression of the IAP family and human telomerase reverse transcriptase (hTERT) in normal colon mucosa from patients with advanced colorectal adenoma and investigated their features according to characteristics of advanced colorectal adenoma. METHODS: While resections of polyps were performed in patients (n = 80) diagnosed with advanced colorectal adenoma or carcinoma in situ, additional normal tissues were obtained from the sigmoid colon...
June 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28697187/can-semiquantitative-measurements-of-suvmax-and-cut-off-values-differentiate-malignant-from-benign-colorectal-cancer
#12
Tram Nguyen, Søren Hess, Henrik Petersen, Abass Alavi, Poul Flemming Høilund-Carlsen
OBJECTIVE: We investigated maximum standardized uptake value (SUVmax) and cut-off values for differentiation of malignant and benign lesions in colorectal cancer (CC) as multiple studies have questioned their validity. We also investigated more extended indices using common semi-quantification analysis in incidental colorectal findings (ICF). SUBJECTS AND METHODS: Fluorine-18-fluoro deoxy glucose positron emission tomography/computed tomography in 25 patients with a total of 30 focal ICF was retrospectively analysed using dedicated software...
July 12, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28689541/-management-of-unexpected-cancer-in-locally-resected-colorectal-polyps
#13
Issam Al-Najami, Gunnar Baatrup
Excised colorectal polyps may contain unexpected malignancy. Once diagnosed histologically, further management is controversial, and little evidence exists to help in the choice between salvage bowel resection, local resection, systemic oncological treatment or watchful waiting. Choice of treatment must take patient-related factors as age and co-morbidity into consideration. Clinicians often face a dilemma concerning further treatment because of the scarce evidence. We want to establish a suggestion of a tailor-made treatment of malignant colorectal polyps based on the given evidence...
July 10, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28689023/profiling-of-cytokines-chemokines-and-other-soluble-proteins-as-a-potential-biomarker-in-colorectal-cancer-and-polyps
#14
Nor Adzimah Johdi, Luqman Mazlan, Ismail Sagap, Rahman Jamal
Soluble proteins including cytokines, chemokines and growth factors are small proteins that mediate and regulate immunity. They involved in the pathogenesis of many diseases including cancers. The concentration of these proteins in biological fluids (serum or plasma) and tissues in diseases may suggest pathway activation that leads to inflammatory response or disease progression. Therefore, these soluble proteins may be useful as a tool for screening, diagnosis classification between stages of disease or surveillance for therapy...
July 6, 2017: Cytokine
https://www.readbyqxmd.com/read/28685081/clinical-endoscopic-and-pathological-characteristics-of-colorectal-polyps-in-elderly-patients-single-center-experience
#15
Lei Zhou, Heng Zhang, Shengbin Sun, Manling Huang, Jing Liu, Dan Xu, Min Song, Chenming Sun, Hui Li, Dan Zheng, Yan Fan, Yusheng Liao, Ping Wang, Jie Wu
Increasing age is a risk factor for the development of colorectal adenomas and advanced adenomas. However, few studies have been published on the features of colorectal polyps in the elderly. The present study aimed to investigate the clinical, enteroscopic and pathological characteristics of colorectal polyps in Chinese elderly patients in a single center (The Central Hospital of Wuhan, Hubei, China). The endoscopic and pathological reports of colonoscopies performed in our center were retrospectively analyzed...
July 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28684185/transabdominal-ultrasound-colonography-for-detection-of-colorectal-neoplasms-initial-clinical-experience
#16
Jin-Ya Liu, Li-Da Chen, Jian-Bo Xu, Hui Wu, Jin-Ning Ye, Xin-Hua Zhang, Xiao-Yan Xie, Wei Wang, Ming-De Lu
We investigated the feasibility of using ultrasound colonography (USC) to visualize the healthy colon and rectum and detect colorectal polyps. Eight healthy volunteers underwent USC after standard bowel preparation. The feasibility and image quality of USC in different segments were evaluated. Then, USC was conducted on eight patients with known colonic neoplasms using colonoscopy as the reference standard. For volunteers, USC examinations were successfully performed on four (50.0%) ascending, three (37.5%) transverse and eight (100%) descending colons, as well as all sigmoid colons and rectums...
July 3, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28682916/risk-factors-of-missed-colorectal-lesions-after-colonoscopy
#17
Jeonghun Lee, Sung Won Park, You Sun Kim, Kyung Jin Lee, Hyun Sung, Pil Hun Song, Won Jae Yoon, Jeong Seop Moon
Several studies have reported a significant rate of missed colorectal polyps during colonoscopy. This study aimed to determine the variables that affect the miss rate of colorectal polyps.We performed a retrospective observational study of patients who, between January 2007 and December 2014, had undergone a second colonoscopy within 6 months of their first. In all patients, the first colonoscopy constituted a screening or surveillance colonoscopy as part of a health check-up, and the patients were referred to the endoscopic clinic if there were meaningful polyps...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28681123/estrogen-receptor-%C3%AE-as-a-prognostic-marker-of-tumor-progression-in-colorectal-cancer-with-familial-adenomatous-polyposis-and-sporadic-polyps
#18
Paulo Roberto Stevanato Filho, Samuel Aguiar Júnior, Maria Dirlei Begnami, Fábio de Oliveira Ferreira, Wilson Toshihiko Nakagawa, Ranyell Matheus Sobreira Batista Spencer, Tiago Santoro Bezerra, Philip Edward Boggiss, Ademar Lopes
The incidence of colorectal cancer (CRC) is lower in women than in men, and sex steroids can be considered contributing factors because oral contraception usage and estrogen replacement therapy are associated with decreased risk. Conversely, colorectal polyp development in familial adenomatous polyposis (FAP) begins during puberty. The objectives were to evaluate the relationship between the expression of these hormone receptors and adenoma-carcinoma progression, CRC stage and overall survival. We studied 120 A...
July 5, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28675538/the-frequency-and-risk-factors-of-colorectal-adenoma-in-patients-with-early-gastric-cancer
#19
Hyun Hee Chung, Kyeong Ok Kim, Si Hyung Lee, Byung Ik Jang, Tae Nyeun Kim
BACKGROUND/AIMS: The authors aimed to determine the clinical value of colonoscopy by evaluating the frequency of colorectal neoplasm detection in patients with early gastric cancer (EGC) as compared with healthy controls and analyzed the risk factors of advanced colorectal neoplasm in patients with EGC. METHODS: The medical records of 201 patients diagnosed as EGC and age and gender matched healthycontrols were retrospectively reviewed. Frequencies and clinical features of colorectal polyps of patients and controls were compared...
July 4, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28670889/heuristic-classifier-for-observe-accuracy-of-cancer-polyp-using-video-capsule-endoscopy
#20
Geetha K, Rajan C
Methods: Colonoscopy is a technique for examine colon cancer, polyps. In endoscopy, video capsule is universally used mechanism for finding gastrointestinal stages. But both the mechanisms are used to find the colon cancer or colorectal polyp. The Automatic Polyp Detection sub-challenge conducted as part of the Endoscopic Vision Challenge (http://endovis.grand-challenge.org). Method: Colonoscopy may be primary way of improve the ability of colon cancer detection especially flat lesions. Which otherwise may be difficult to detect...
June 25, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
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