keyword
MENU ▼
Read by QxMD icon Read
search

Colorectal polyps

keyword
https://www.readbyqxmd.com/read/28103453/-analysis-of-the-cochrane-review-chromoscopy-versus-conventional-endoscopy-for-the-detection-of-polyps-in-the-colon-and-rectum-cochrane-database-syst-rev-2016-4-cd006439
#1
Diogo Libânio, Luís Filipe Azevedo
Although colonoscopy is considered the most accurate test for the investigation of colorectal polyps, lesions ≤ 10 mm may be missed in approximately 10%. Chromoscopy may increase the detection of colorectal polyps. A systematic review and meta-analysis was performed to investigate the benefit of cromoscopy in colorectal polyps detection. Seven randomized controlled trials were included (incuding 2,727 participants) comparing polyp detection (both neoplastic and non- neoplastic polyps) in patients submitted to conventional colonoscopy or colonoscopy with chromoscopy...
October 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28091843/the-incidence-of-post-colonoscopy-colorectal-cancer-a-retrospective-long-term-cohort-study-using-a-colonoscopy-database
#2
Ayako Nakada, Ryota Niikura, Atsuo Yamada, Shuntaro Yoshida, Yoshihiro Hirata, Kazuhiko Koike
PURPOSE: The cumulative incidence of post-colonoscopy colorectal cancer remains unclear. Our aims were to estimate the incidence of and identify risk factors associated with post-colonoscopy colorectal cancer. METHODS: We conducted a retrospective cohort study using the colonoscopy database of the Department of Gastroenterology, the University of Tokyo Hospital Records from1995-2012. A cohort of 2544 patients, who received multiple colonoscopies without colorectal cancer findings at first colonoscopy, was selected...
January 14, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28090006/expression-of-apical-junction-complex-proteins-in-colorectal-mucosa-of-miniature-dachshunds-with-inflammatory-colorectal-polyps
#3
Nozomu Yokoyama, Hiroshi Ohta, Yumiko Kagawa, Rommaneeya Leela-Arporn, Angkhana Dermlim, Khoirun Nisa, Tomoya Morita, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Mitsuyoshi Takiguchi
We examine the expression of tight junction and adherence junction proteins in the colorectal mucosa of miniature dachshunds (MDs) with inflammatory colorectal polyps (ICRPs). Colorectal mucosa samples were endoscopically obtained from 8 MDs with ICRPs and 8 control dogs for immunoblotting. Paraffin-embedded tissues of surgically resected inflamed lesions from another 5 MDs with ICRPs and full-thickness colorectal specimens from 5 healthy beagles were obtained for immunohistochemistry. The expression patterns of claudin-1, -2, -3, -4, -5, -7 and -8, E-cadherin and β-catenin were analyzed in the non-inflamed mucosa and inflamed mucosa of ICRPs and colorectal mucosa of control dogs by immunoblotting...
January 16, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28089357/localization-of-toll-like-receptor-tlr-2-and-tlr4-mrna-in-the-colorectal-mucosa-of-miniature-dachshunds-with-inflammatory-colorectal-polyps
#4
N Yokoyama, H Ohta, J Yamazaki, Y Kagawa, O Ichii, N Khoirun, T Morita, T Osuga, S Y Lim, N Sasaki, K Morishita, K Nakamura, M Takiguchi
Inflammatory colorectal polyps (ICRPs) are characterized by the formation of multiple or solitary polyps with marked neutrophil infiltration in the colorectal area, and are speculated to be a novel form of breed-specific canine idiopathic inflammatory bowel disease (IBD). In human IBD, toll-like receptor (TLR) 2 and TLR4 have been reported to be involved in the pathogenesis of the disease. The aim of this study was to evaluate the expression of TLR2 and TLR4 mRNA in the colorectal mucosa of dogs with ICRPs by in-situ hybridization using an RNAscope assay...
January 12, 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28078114/colorectal-cancer-anatomic-distribution-patterns-remain-the-same-after-sessile-serrated-adenoma-polyp-considered-cancer-precursor-a-9-year-comparison-study-from-community-based-endoscopy-centers
#5
Juliana F Yang, Amy E Noffsinger, Deepak Agrawal, Qing-Hua Yang
BACKGROUND: The overall incidence of colorectal cancer (CRC) in the United States has steadily decreased. However, the incidence of right-sided CRC remains unchanged for the past two decades. The serrated neoplastic pathway (sessile serrated adenoma/polyp, SSA/P) has been considered an important pathway of colorectal carcinogenesis, especially in the right-sided CRC. The aim of this study was to compare CRC anatomic distribution patterns in a 9-year interval in the general population before and after SSA/P was recognized and treated as a CRC precursor...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28075483/detecting-apc-gene-mutations-in-familial-adenomatous-polyposis-fap
#6
Babi Ramesh Reddy Nallamilli, Madhuri Hegde
Hereditary forms of colorectal cancer (CRC) account for up to 5% of total cases. Familial adenomatous polyposis (FAP) is an autosomal dominant condition affecting nearly 1 in 5000 people and accounts for only about 1% of all CRCs. It is characterized by the progressive development of hundreds to thousands of adenomatous colon polyps. The gene associated with FAP (APC) contains 15 coding exons. The mutation spectrum of the APC gene is broad in that 87% of causative mutations are point mutations (including other sequence variants) and around 10% to 15% are intragenic deletions and duplications...
January 11, 2017: Current Protocols in Human Genetics
https://www.readbyqxmd.com/read/28070659/diagnosis-treatment-and-consequences-of-anastomotic-leakage-in-colorectal-surgery
#7
Bodil Gessler, Olle Eriksson, Eva Angenete
PURPOSE: The aim of this study was to explore the choice of modality for diagnosis, treatments, and consequences of anastomotic leakage. METHODS: This is a retrospective study of consecutive patients who underwent surgery that included a colorectal anastomosis due to colorectal cancer, diverticulitis, inflammatory bowel disease (IBD), or benign polyps. RESULTS: A total of 600 patients were included during 2010-2012, and 60 (10%) had an anastomotic leakage...
January 9, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28070233/complete-rectal-prolapse-in-young-egyptian-males-is-schistosomiasis-really-condemned
#8
Ahmed A Abou-Zeid, Islam H ElAbbassy, Ahmed M Kamal, Dina A Somaie
AIM: To investigate the assumption that schistosomiasis is the main cause of rectal prolapse in young Egyptian males. METHODS: Twenty-one male patients between ages of 18 and 50 years with complete rectal prolapse were included in the study out of a total 29 patients with rectal prolapse admitted for surgery at Colorectal Surgery Unit, Ain Shams University hospitals between the period of January 2011 and April 2014. Patients were asked to fill out a specifically designed questionnaire about duration of the prolapse, different bowel symptoms and any past or present history of schistosomiasis...
December 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28069476/missed-adenomas-with-behind-folds-visualizing-colonoscopy-technologies-compared-with-standard-colonoscopy-a-pooled-analysis-of-3-randomized-back-to-back-tandem-colonoscopy-studies
#9
Eelco C Brand, Vincent K Dik, Martijn G H van Oijen, Peter D Siersema
BACKGROUND AND AIMS: The Third Eye Retroscope, Full Spectrum Endoscope (FUSE) and EndoRings device have been shown to reduce overall adenoma miss rates. We evaluated the characteristics of adenomas and patient subgroups for which these "behind folds visualizing" technologies mostly reduce adenoma miss rates. METHODS: Data of 3 multicenter randomized trials (NCT01044732; NCT01549535; NCT01955122) were combined. Patients underwent same-day, back-to-back tandem examinations with standard colonoscopy and Third Eye Retroscope, FUSE or EndoRings colonoscopy, respectively...
January 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28064440/dietary-fibre-for-the-prevention-of-recurrent-colorectal-adenomas-and-carcinomas
#10
REVIEW
Yibo Yao, Tao Suo, Roland Andersson, Yongqing Cao, Chen Wang, Jingen Lu, Evelyne Chui
BACKGROUND: This is an update of the Cochrane review published in 2002.Colorectal cancer (CRC) is a major cause of morbidity and mortality in industrialised countries. Experimental evidence has supported the hypothesis that dietary fibre may protect against the development of CRC, although epidemiologic data have been inconclusive. OBJECTIVES: To assess the effect of dietary fibre on the recurrence of colorectal adenomatous polyps in people with a known history of adenomatous polyps and on the incidence of CRC compared to placebo...
January 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28054186/radiographic-capsule-based-system-for-non-cathartic-colorectal-cancer-screening
#11
Yoav Kimchy, Ronen Lifshitz, Shlomo Lewkowitz, Guiseppe Bertuccio, Nadir Arber, Nathan Gluck, Perry J Pickhardt
Many patients are reluctant to undergo optical colonoscopy for colorectal cancer screening. The Check-Cap colon imaging system is a non-invasive test that comprises an ingestible imaging capsule that emits and detects ultra-low-dose radiation. The capsule generates a 3D reconstruction of the colonic lumen for detection of polyps and cancer. Preliminary preclinical and clinical testing has demonstrated safety and feasibility. Mean radiation dose is estimated at 0.04 mSv. In conclusion, we describe a novel capsule-based, patient-friendly colorectal test that holds potential for non-invasive screening...
January 4, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28052292/evaluation-for-the-clinical-efficacy-of-colon-capsule-endoscopy-in-the-detection-of-laterally-spreading-tumors
#12
Atsushi Igawa, Shiro Oka, Shinji Tanaka, Ichiro Otani, Sayoko Kunihara, Kazuaki Chayama
BACKGROUND AND AIM: The manner in which colorectal lesions are being detected with PillCam COLON2 capsule endoscopy (CCE2) has markedly improved in recent days. However, limited data are available on CCE2 for detecting laterally spreading tumors (LSTs). The aim of this study was to compare CCE2 with optical colonoscopy (OC), which is currently the gold standard used in the detection of LSTs. METHODS: We performed a prospective, single-academic center study comparing CCE2 with OC in patients with LSTs diagnosed using OC, which was performed during the 3-month period prior to CCE2...
2017: Digestion
https://www.readbyqxmd.com/read/28041973/prognostic-significance-of-stromal-grem1-expression-in-colorectal-cancer
#13
Bo Gun Jang, Hye Sung Kim, Weon Young Chang, Jeong Mo Bae, Hyeon Jeong Oh, Xianyu Wen, Seorin Jeong, Nam Yun Cho, Woo Ho Kim, Gyeong Hoon Kang
Cancer associated fibroblasts (CAFs) are the dominant cell population in the cancer stroma. Gremlin 1 (GREM1), an antagonist of the bone morphogenetic protein pathway, is expressed by CAFs in a variety of human cancers. However, its biological significance for cancer patients is largely unknown. We applied RNA in situ hybridization (ISH) to evaluate the prognostic value of stromal GREM1 expression in a large cohort of 670 colorectal cancers (CRCs). Overall GREM1 expression in CRCs was lower than that of the matched normal mucosa, and GREM1 expression had a strong positive correlation with BMI1 and inverse correlations with EPHB2 and OLFM4...
December 29, 2016: Human Pathology
https://www.readbyqxmd.com/read/28038683/the-gut-microbiota-in-conventional-and-serrated-precursors-of-colorectal-cancer
#14
Brandilyn A Peters, Christine Dominianni, Jean A Shapiro, Timothy R Church, Jing Wu, George Miller, Elizabeth Yuen, Hal Freiman, Ian Lustbader, James Salik, Charles Friedlander, Richard B Hayes, Jiyoung Ahn
BACKGROUND: Colorectal cancer is a heterogeneous disease arising from at least two precursors-the conventional adenoma (CA) and the serrated polyp. We and others have previously shown a relationship between the human gut microbiota and colorectal cancer; however, its relationship to the different early precursors of colorectal cancer is understudied. We tested, for the first time, the relationship of the gut microbiota to specific colorectal polyp types. RESULTS: Gut microbiota were assessed in 540 colonoscopy-screened adults by 16S rRNA gene sequencing of stool samples...
December 30, 2016: Microbiome
https://www.readbyqxmd.com/read/28035253/colon-adenoma-features-and-their-impact-on-risk-of-future-advanced-adenomas-and-colorectal-cancer
#15
Audrey H Calderwood, Karen E Lasser, Hemant K Roy
AIM: To review the evidence on the association between specific colon adenoma features and the risk of future colonic neoplasia [adenomas and colorectal cancer (CRC)]. METHODS: We performed a literature search using the National Library of Medicine through PubMed from 1/1/2003 to 5/30/2015. Specific Medical Subject Headings terms (colon, colon polyps, adenomatous polyps, epidemiology, natural history, growth, cancer screening, colonoscopy, CRC) were used in conjunction with subject headings/key words (surveillance, adenoma surveillance, polypectomy surveillance, and serrated adenoma)...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28035250/from-traditional-serrated-adenoma-to-tubulovillous-adenoma-and-beyond
#16
REVIEW
Sangeetha N Kalimuthu, Adeline Chelliah, Runjan Chetty
It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated polyps. TSAs are characterised by the presence of a "pinecone-like" architecture, granular eosinophilic cytoplasm, luminal serrations, ectopic crypt foci (ECF) and elongated, pencillate nuclei. However, the distinct slit-like luminal serrations, reminiscent of small bowel mucosa, appear to be the most unique and reproducible feature to distinguish TSAs from other polyps...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28026076/ethical-issues-with-colorectal-cancer-screening-a-systematic-review
#17
Bjørn Hofmann
RATIONALE, AIMS, AND OBJECTIVES: Colorectal cancer (CRC) screening is widely recommended and implemented. However, sometimes CRC screening is not implemented despite good evidence, and some types of CRC screening are implemented despite lack of evidence. The objective of this article is to expose and elucidate relevant ethical issues in the literature on CRC screening that are important for open and transparent deliberation on CRC screening. METHODS: An axiological question-based method is used for exposing and elucidating ethical issues relevant in HTA...
December 27, 2016: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28025763/helicobacter-pylori-infection-is-an-independent-risk-factor-for-colonic-adenomatous-neoplasms
#18
Ji Hyung Nam, Chang Won Hong, Byung Chang Kim, Aesun Shin, Kum Hei Ryu, Bum Joon Park, Bun Kim, Dae Kyung Sohn, Kyung Su Han, Jeongseon Kim, Chan Wha Lee
PURPOSE: Helicobacter pylori infection is considered to have a positive association with colorectal neoplasms. In this study, we evaluated the association between H. pylori infection and colorectal adenomas, based on the characteristics of these adenomas in Korea, where the prevalence of H. pylori infection is high and the incidence of colorectal cancer continues to increase. METHODS: The study cohort consisted of 4,466 subjects who underwent colonoscopy and esophagogastroduodenoscopy during screening (1,245 colorectal adenomas vs...
December 27, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28025471/-new-colonoscopy-devices-to-improve-colon-neoplasm-detection
#19
REVIEW
Sung Jae Shin
Early detection and removal of adenomatous polyps can prevent the development of colorectal cancer. However, it is fairly common-up to 20%-for polyps to be undetected in a colonoscopy due to poor visualization of the proximal aspect of colonic folds and anatomical flexures. To overcome these limitations, many new endoscopes and accessories have been developed. A wide-angle colonoscopy did not improve the detection of adenoma compared with the standard colonoscopy. An extra-wide angle and Retroview colonoscopies showed a significantly lower miss rate of polyps in the colon model...
December 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28024986/the-natural-history-of-diminutive-and-small-colorectal-polyps-a-systematic-literature-review
#20
REVIEW
Jasper L A Vleugels, Yark Hazewinkel, Paul Fockens, Evelien Dekker
BACKGROUND: Diminutive (1-5 mm) and small (6-9 mm) polyps comprise 90% of detected lesions during colonoscopy and rarely contain advanced histology or colorectal cancer (CRC). Routine removal of these lesions results in a significant burden to colonoscopy programs. At the same time, the risk for progression of these polyps to CRC is unclear. We performed a systematic review to explore the natural history of diminutive and small colorectal polyps. METHODS: We searched MEDLINE and EMBASE for studies investigating the natural history of colorectal polyps...
December 23, 2016: Gastrointestinal Endoscopy
keyword
keyword
24137
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"