keyword
MENU ▼
Read by QxMD icon Read
search

Hyperacusis

keyword
https://www.readbyqxmd.com/read/27920720/validation-of-online-versions-of-tinnitus-questionnaires-translated-into-swedish
#1
Karolina Müller, Niklas K Edvall, Esma Idrizbegovic, Robert Huhn, Rilana Cima, Viktor Persson, Constanze Leineweber, Hugo Westerlund, Berthold Langguth, Winfried Schlee, Barbara Canlon, Christopher R Cederroth
Background: Due to the lack of objective measures for assessing tinnitus, its clinical evaluation largely relies on the use of questionnaires and psychoacoustic tests. A global assessment of tinnitus burden would largely benefit from holistic approaches that not only incorporate measures of tinnitus but also take into account associated fears, emotional aspects (stress, anxiety, and depression), and quality of life. In Sweden, only a few instruments are available for assessing tinnitus, and the existing tools lack validation...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27895575/can-animal-models-contribute-to-understanding-tinnitus-heterogeneity-in-humans
#2
REVIEW
Jos J Eggermont
The brain activity of humans with tinnitus of various etiologies is typically studied with electro- and magneto-encephalography and functional magnetic resonance imaging-based imaging techniques. Consequently, they measure population responses and mostly from the neocortex. The latter also underlies changes in neural networks that may be attributed to tinnitus. However, factors not strictly related to tinnitus such as hearing loss and hyperacusis, as well as other co-occurring disorders play a prominent role in these changes...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27862478/reductions-in-cortical-alpha-activity-enhancements-in-neural-responses-and-impaired-gap-detection-caused-by-sodium-salicylate-in-awake-guinea-pigs
#3
Joel I Berger, Ben Coomber, Mark N Wallace, Alan R Palmer
Tinnitus chronically affects between 10-15% of the population but despite its prevalence, the underlying mechanisms are still not properly understood. One experimental model involves administration of high doses of sodium salicylate, as this is known to reliably induce tinnitus in both humans and animals. Guinea pigs were implanted with chronic electrocorticography (ECoG) electrode arrays, with silver ball electrodes placed on the dura over left and right auditory cortex. Two more electrodes were positioned over the cerebellum to monitor auditory brainstem responses (ABRs)...
November 12, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27793584/effects-of-long-term-non-traumatic-noise-exposure-on-the-adult-central-auditory-system-hearing-problems-without-hearing-loss
#4
REVIEW
Jos J Eggermont
It is known that hearing loss induces plastic changes in the brain, causing loudness recruitment and hyperacusis, increased spontaneous firing rates and neural synchrony, reorganizations of the cortical tonotopic maps, and tinnitus. Much less in known about the central effects of exposure to sounds that cause a temporary hearing loss, affect the ribbon synapses in the inner hair cells, and cause a loss of high-threshold auditory nerve fibers. In contrast there is a wealth of information about central effects of long-duration sound exposures at levels ≤ 80 dB SPL that do not even cause a temporary hearing loss...
October 25, 2016: Hearing Research
https://www.readbyqxmd.com/read/27746216/early-age-noise-exposure-increases-loudness-perception-a-novel-animal-model-of-hyperacusis
#5
Ana'am Alkharabsheh, Fen Xiong, Senthilvelan Manohar, Guangdi Chen, Richard Salvi, Wei Sun
The neural mechanisms that give rise to hyperacusis, a reduction in loudness tolerance, are largely unknown. Some reports suggest that hyperacusis is linked to childhood hearing loss. However, the evidence for this is largely circumstantial. In order to rigorously test this hypothesis, we studied loudness changes in rats caused by intense noise exposure (12 kHz narrow band noise, 115 dB SPL, 4 h) at postnatal 16 days. Rats without noise exposure were used as controls. The exposed noise group (n = 7) showed a mean 40-50 dB hearing loss compared to the control group (n = 8) at high frequencies (>= 8 kHz) and less hearing loss at lower frequencies...
October 13, 2016: Hearing Research
https://www.readbyqxmd.com/read/27742966/-dehiscence-syndromes-diagnosis-and-treatment
#6
A Ernst, I Todt, J Wagner
BACKGROUND: Dehiscence syndromes of the semicircular canals are a relatively new group of neurotological disorders. They have a variety of symptoms with hearing/balance involvement. Younger patients have clinically relevant symptoms in only about one third of cases. In addition to etiology and pathogenesis, the present paper describes diagnostic and therapeutic possibilities using a patient series of the authors. MATERIALS AND METHODS: This nonrandomized prospective study included 52 patients with uni-/bilateral dehiscence syndromes of the superior and/or posterior canal (SCDS/PCDS), diagnosed with high-resolution computed tomography (HR-CT) of the petrous bone...
October 14, 2016: HNO
https://www.readbyqxmd.com/read/27728719/scrub-typhus-with-hyperacusis-and-tinnitus
#7
Alfia Rachel Kaki, Sowmya Satyendra
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27683915/conductive-hearing-loss-has-long-lasting-structural-and-molecular-effects-on-presynaptic-and-postsynaptic-structures-of-auditory-nerve-synapses-in-the-cochlear-nucleus
#8
Cheryl Clarkson, Flora M Antunes, Maria E Rubio
UNLABELLED: Sound deprivation by conductive hearing loss increases hearing thresholds, but little is known about the response of the auditory brainstem during and after conductive hearing loss. Here, we show in young adult rats that 10 d of monaural conductive hearing loss (i.e., earplugging) leads to hearing deficits that persist after sound levels are restored. Hearing thresholds in response to clicks and frequencies higher than 8 kHz remain increased after a 10 d recovery period. Neural output from the cochlear nucleus measured at 10 dB above threshold is reduced and followed by an overcompensation at the level of the lateral lemniscus...
September 28, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27681261/survey-on-the-effectiveness-of-dietary-supplements-to-treat-tinnitus
#9
Claudia Coelho, Richard Tyler, Haihong Ji, Eveling Rojas-Roncancio, Shelley Witt, Pan Tao, Hyung-Jin Jun, Tang Chuan Wang, Marlan R Hansen, Bruce J Gantz
PURPOSE: We surveyed the benefit of dietary supplements to treat tinnitus and reported adverse effects. METHOD: A website was created for people with tinnitus to complete a variety of questions. RESULTS: The 1,788 subjects who responded to questionnaires came from 53 different countries; 413 (23.1%) reported taking supplements. No effect on tinnitus was reported in 70.7%, improvement in 19.0%, and worsening in 10.3%. Adverse effects were reported in 6% (n = 36), including bleeding, diarrhea, headache, and others...
September 1, 2016: American Journal of Audiology
https://www.readbyqxmd.com/read/27668792/minimally-invasive-surgery-for-the-treatment-of-hyperacusis
#10
Herbert Silverstein, Rosemary Ojo, Julie Daugherty, Ronen Nazarian, Jack Wazen
OBJECTIVE: To evaluate the efficacy of a minimally invasive surgical procedure in patients with severe hyperacusis. STUDY DESIGN: Prospective, longitudinal design. SETTING: Tertiary referral center. PATIENTS: Adult patients with history of severe hyperacusis. INTERVENTION: Using a transcanal approach, the round and oval window was reinforced with temporalis fascia or tragal perichondrium in six subjects (nine ears) and was subdivided into two groups (unilateral or bilateral reinforcement procedure)...
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27630564/reactive-neurogenesis-and-down-regulation-of-the-potassium-chloride-cotransporter-kcc2-in-the-cochlear-nuclei-after-cochlear-deafferentation
#11
Brahim Tighilet, Sophie Dutheil, Marina I Siponen, Arnaud J Noreña
While many studies have been devoted to investigating the homeostatic plasticity triggered by cochlear hearing loss, the cellular and molecular mechanisms involved in these central changes remain elusive. In the present study, we investigated the possibility of reactive neurogenesis after unilateral cochlear nerve section in the cochlear nucleus (CN) of cats. We found a strong cell proliferation in all the CN sub-divisions ipsilateral to the lesion. Most of the newly generated cells survive up to 1 month after cochlear deafferentation in all cochlear nuclei (except the dorsal CN) and give rise to a variety of cell types, i...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27619040/demographic-data-referral-patterns-and-interventions-used-for-children-and-adolescents-with-tinnitus-and-hyperacusis-in-denmark
#12
Susanne Nemholt Rosing, Anestis Kapandais, Jesper Hvass Schmidt, David M Baguley
OBJECTIVES: To investigate whether children and adolescents with tinnitus and/or hyperacusis are seen in Ear-Nose-Throat (ENT) clinics and to report the clinical data, treatment and referral patterns of these children. To describe the population of children and adolescents with tinnitus and/or hyperacusis found in Educational- Psychological Advisory services (EPAs) and Centres for special Education for Adults (CEAs) and to identify the referral patterns and interventions used for the children in each of these settings...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27618300/toward-a-differential-diagnosis-of-hidden-hearing-loss-in-humans
#13
M Charles Liberman, Michael J Epstein, Sandra S Cleveland, Haobing Wang, Stéphane F Maison
Recent work suggests that hair cells are not the most vulnerable elements in the inner ear; rather, it is the synapses between hair cells and cochlear nerve terminals that degenerate first in the aging or noise-exposed ear. This primary neural degeneration does not affect hearing thresholds, but likely contributes to problems understanding speech in difficult listening environments, and may be important in the generation of tinnitus and/or hyperacusis. To look for signs of cochlear synaptopathy in humans, we recruited college students and divided them into low-risk and high-risk groups based on self-report of noise exposure and use of hearing protection...
2016: PloS One
https://www.readbyqxmd.com/read/27569405/characteristics-of-hyperacusis-in-the-general-population
#14
Johan Paulin, Linus Andersson, Steven Nordin
There is a need for better understanding of various characteristics in hyperacusis in the general population. The objectives of the present study were to investigate individuals in the general population with hyperacusis regarding demographics, lifestyle, perceived general health and hearing ability, hyperacusis-specific characteristics and behavior, and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated individuals with physician-diagnosed (n = 66) and self-reported (n = 313) hyperacusis in comparison to individuals without hyperacusis (n = 2995)...
July 2016: Noise & Health
https://www.readbyqxmd.com/read/27531021/pathophysiology-of-the-inner-ear-after-blast-injury-caused-by-laser-induced-shock-wave
#15
Katsuki Niwa, Kunio Mizutari, Toshiyasu Matsui, Takaomi Kurioka, Takeshi Matsunobu, Satoko Kawauchi, Yasushi Satoh, Shunichi Sato, Akihiro Shiotani, Yasushi Kobayashi
The ear is the organ that is most sensitive to blast overpressure, and ear damage is most frequently seen after blast exposure. Blast overpressure to the ear results in sensorineural hearing loss, which is untreatable and is often associated with a decline in the quality of life. In this study, we used a rat model to demonstrate the pathophysiological and structural changes in the inner ear that replicate pure sensorineural hearing loss associated with blast injury using laser-induced shock wave (LISW) without any conductive hearing loss...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27473923/noise-induced-hearing-loss-neuropathic-pain-via-ntrk1-signaling
#16
Senthilvelan Manohar, Kimberly Dahar, Henry J Adler, Ding Dalian, Richard Salvi
Severe noise-induced damage to the inner ear leads to auditory nerve fiber degeneration thereby reducing the neural input to the cochlear nucleus (CN). Paradoxically, this leads to a significant increase in spontaneous activity in the CN which has been linked to tinnitus, hyperacusis and ear pain. The biological mechanisms that lead to an increased spontaneous activity are largely unknown, but could arise from changes in glutamatergic or GABAergic neurotransmission or neuroinflammation. To test this hypothesis, we unilaterally exposed rats for 2h to a 126dB SPL narrow band noise centered at 12kHz...
September 2016: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/27445661/decreased-speech-in-noise-understanding-in-young-adults-with-tinnitus
#17
Annick Gilles, Winny Schlee, Sarah Rabau, Kristien Wouters, Erik Fransen, Paul Van de Heyning
OBJECTIVES: Young people are often exposed to high music levels which make them more at risk to develop noise-induced symptoms such as hearing loss, hyperacusis, and tinnitus of which the latter is the symptom perceived the most by young adults. Although, subclinical neural damage was demonstrated in animal experiments, the human correlate remains under debate. Controversy exists on the underlying condition of young adults with normal hearing thresholds and noise-induced tinnitus (NIT) due to leisure noise...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27402091/gm2-gangliosidosis-ab-variant-novel-mutation-from-india-a-case-report-with-a-review
#18
Jayesh Sheth, Chaitanya Datar, Mehul Mistri, Riddhi Bhavsar, Frenny Sheth, Krati Shah
BACKGROUND: GM2 gangliosidosis-AB variants a rare autosomal recessive neurodegenerative disorder occurring due to deficiency of GM2 activator protein resulting from the mutation in GM2A gene. Only seven mutations in nine cases have been reported from different population except India. CASE PRESENTATION: Present case is a one year old male born to 3rd degree consanguineous Indian parents from Maharashtra. He was presented with global developmental delay, hypotonia and sensitive to hyperacusis...
2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27329351/hearing-thresholds-tinnitus-and-headphone-listening-habits-in-nine-year-old-children
#19
Sara Båsjö, Claes Möller, Stephen Widén, Göran Jutengren, Kim Kähäri
OBJECTIVE: Investigate hearing function and headphone listening habits in nine-year-old Swedish children. DESIGN: A cross-sectional study was conducted and included otoscopy, tympanometry, pure-tone audiometry, and spontaneous otoacoustic emissions (SOAE). A questionnaire was used to evaluate headphone listening habits, tinnitus, and hyperacusis. STUDY SAMPLE: A total of 415 children aged nine years. RESULTS: The prevalence of a hearing threshold ≥20 dB HL at one or several frequencies was 53%, and the hearing thresholds at 6 and 8 kHz were higher than those at the low and mid frequencies...
October 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27259524/prevalence-of-tinnitus-and-hyperacusis-in-children-and-adolescents-a-systematic-review
#20
Susanne Nemholt Rosing, Jesper Hvass Schmidt, Niels Wedderkopp, David M Baguley
OBJECTIVES: To systematically review studies of the epidemiology of tinnitus and hyperacusis in children and young people, in order to determine the methodological differences implicated in the variability of prevalence estimates and the influence of population characteristics on childhood tinnitus and hyperacusis. DATA SOURCES: Articles were retrieved from PubMed, EMBASE and Scopus databases and from the relevant reference lists using the methods described in the study protocol, which has previously been published...
2016: BMJ Open
keyword
keyword
24133
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"