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Hyperacusis

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https://www.readbyqxmd.com/read/28627931/hyperacoustic-hypoacusis-a-new-pontine-syndrome-case-report
#1
Mohammad Hassan A Noureldine, Raghid Kikano, Naji Riachi, Rechdi Ahdab
We herein report a unique case of a lateral pontine demyelinating lesion presenting with unilateral sensorineural hearing loss and paradoxical ipsilateral hyperacusis. The association of unilateral hearing loss and ipsilateral hyperacusis is a rare manifestation of a central nervous system lesion. The paradoxical combination of these symptoms strongly suggests pontine dysfunction and prompts urgent neurological evaluation.
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28625091/factors-related-to-tinnitus-and-hyperacusis-handicap-in-older-people
#2
Hashir Aazh, Karen Lammaing, Brian C J Moore
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people. DESIGN: Retrospective cross-sectional. STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years. RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2...
June 18, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28622055/factors-related-to-uncomfortable-loudness-levels-for-patients-seen-in-a-tinnitus-and-hyperacusis-clinic
#3
Hashir Aazh, Brian C J Moore
OBJECTIVES: The aims were as follows: (1) to explore patterns of uncomfortable loudness levels (ULLs) across frequency and their associated factors for patients with tinnitus and hyperacusis, and (2) to re-evaluate the criteria for diagnosing hyperacusis based on ULLs and scores for the Hyperacusis Questionnaire (HQ). DESIGN: This was a retrospective cross-sectional study. STUDY SAMPLE: 573 consecutive patients for whom ULLs had been measured were included...
June 16, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28592687/efferent-inhibition-strength-is-a-physiological-correlate-of-hyperacusis-in-children-with-autism-spectrum-disorder
#4
Uzma S Wilson, Kate M Sadler, Kenneth E Hancock, John J Guinan, Jeffery T Lichtenhan
Autism spectrum disorder (ASD) is a developmental disability that is poorly understood. ASD can influence communication, social interaction, and behavior. Children with ASD often have sensory hypersensitivities, including auditory hypersensitivity (hyperacusis). In adults with hyperacusis who are otherwise neurotypical, the medial olivocochlear (MOC) efferent reflex is stronger than usual. In children with ASD the MOC reflex has been measured, but without also assessing hyperacusis. We assessed the MOC reflex in children with ASD by measuring the strength of MOC-induced inhibition of transient-evoked otoacoustic emissions (TEOAEs), a non-invasive, physiological measure that reflects cochlear amplification...
June 7, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28583912/noise-trauma-induced-behavioral-gap-detection-deficits-correlate-with-reorganization-of-excitatory-and-inhibitory-local-circuits-in-the-inferior-colliculus-and-are-prevented-by-acoustic-enrichment
#5
Joshua J Sturm, Ying-Xin Zhang-Hooks, Hannah Roos, Tuan Nguyen, Karl Kandler
Hearing loss leads to a host of cellular and synaptic changes in auditory brain areas, which are thought to give rise to auditory perception deficits such as temporal processing impairments, hyperacusis, or tinnitus. However, little is known about possible changes in synaptic circuit connectivity that may underlie these hearing deficits. Here, we show that mild hearing loss as a result of brief noise exposure leads to a pronounced reorganization of local excitatory and inhibitory circuits in the mouse inferior colliculus...
June 5, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28503164/superior-canal-dehiscence-syndrome-lessons-from-the-first-20-years
#6
REVIEW
Bryan K Ward, John P Carey, Lloyd B Minor
Superior semicircular canal dehiscence syndrome was first reported by Lloyd Minor and colleagues in 1998. Patients with a dehiscence in the bone overlying the superior semicircular canal experience symptoms of pressure or sound-induced vertigo, bone conduction hyperacusis, and pulsatile tinnitus. The initial series of patients were diagnosed based on common symptoms, a physical examination finding of eye movements in the plane of the superior semicircular canal when ear canal pressure or loud tones were applied to the ear, and high-resolution computed tomography imaging demonstrating a dehiscence in the bone over the superior semicircular canal...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28463806/salicylate-induced-hyperacusis-in-rats-dose-and-frequency-dependent-effects
#7
Kelly Radziwon, David Holfoth, Julia Lindner, Zoe Kaier-Green, Rachael Bowler, Maxwell Urban, Richard Salvi
The use of auditory reaction time is a reliable measure of loudness perception in both animals and humans with reaction times (RT) decreasing with increasing stimulus intensity. Since abnormal loudness perception is a common feature of hyperacusis, a potentially debilitating auditory disorder in which moderate-intensity sounds are perceived as uncomfortable or painfully loud, we used RT measures to assess rats for salicylate-induced hyperacusis. A previous study using an operant conditioning RT procedure found that high-dose sodium salicylate (SS) induced hyperacusis-like behavior, i...
July 2017: Hearing Research
https://www.readbyqxmd.com/read/28431308/hyperexcitability-of-inferior-colliculus-and-acoustic-startle-reflex-with-age-related-hearing-loss
#8
Binbin Xiong, Ana'am Alkharabsheh, Senthilvelan Manohar, Guang-Di Chen, Ning Yu, Xiaoming Zhao, Richard Salvi, Wei Sun
Chronic tinnitus and hyperacusis often develop with age-related hearing loss presumably due to aberrant neural activity in the central auditory system (CAS) induced by cochlear pathologies. However, the full spectrum of physiological changes that occur in the CAS as a result age-related hearing loss are still poorly understood. To address this issue, neurophysiological measures were obtained from the cochlea and the inferior colliculus (IC) of 2, 6 and 12 month old C57BL/6J mice, a mouse model for early age-related hearing loss...
March 27, 2017: Hearing Research
https://www.readbyqxmd.com/read/28418328/internet-based-intervention-for-tinnitus-outcome-of-a-single-group-open-trial
#9
Eldré W Beukes, Peter M Allen, Vinaya Manchaiah, David M Baguley, Gerhard Andersson
BACKGROUND: Managing chronic tinnitus is challenging, and innovative ways to address the resulting health-care burden are required. Internet-based cognitive behavioral therapy (iCBT) for tinnitus shows promise as a cost-effective treatment option. The feasibility and effectiveness of iCBT in the United Kingdom are yet to be explored. Furthermore, it is not known if iCBT can be supported by an audiologist rather than a psychologist. PURPOSE: This study aimed to determine the feasibility of guided iCBT using audiological support on tinnitus distress and tinnitus-related comorbidities...
April 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28418323/the-personality-profile-of-tinnitus-sufferers-and-a-nontinnitus-control-group
#10
Mithila Durai, Mary G O'Keeffe, Grant D Searchfield
BACKGROUND: Chronic tinnitus (phantom perception of sound) significantly disrupts quality of life in 15-20% of those who experience it. Understanding how certain personality traits impact tinnitus perception and distress can be beneficial for the development of interventions to improve the lives of tinnitus sufferers. PURPOSE: Four key self-reported personality traits (social closeness, stress reaction, alienation, and self-control) were identified from previous research as being associated with tinnitus...
April 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28394666/assessment-of-hyperacusis-with-a-newly-produced-japanese-version-of-the-khalfa-hyperacusis-questionnaire
#11
Naoki Oishi, Hiroyuki Yamada, Sho Kanzaki, Akihiro Kurita, Yoichiro Takiguchi, Isamu Yuge, Yoji Asama, Masatsugu Masuda, Kaoru Ogawa
OBJECTIVES: The purpose of this study was to determine the validity and reliability of a Japanese version of the Khalfa hyperacusis questionnaire (KHQ) and proposed a threshold KHQ score for classifying hyperacusis. METHODS: In total, 112 patients with hyperacusis (group A) and 103 patients without hyperacusis (group B). The patients in group A were further classified into the following subgroups: subjects with hyperacusis as their chief complaint (n = 26, group A1) and subjects with hyperacusis accompanied by chief complaints of tinnitus and/or hearing loss (n = 86, group A2)...
April 10, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28384694/auditory-phenotype-of-smith-magenis-syndrome
#12
Megan A Brendal, Kelly A King, Christopher K Zalewski, Brenda M Finucane, Wendy Introne, Carmen C Brewer, Ann C M Smith
Purpose: The purpose of this study was to describe the auditory phenotype of a large cohort with Smith-Magenis syndrome (SMS), a rare disorder including physical anomalies, cognitive deficits, sleep disturbances, and a distinct behavioral phenotype. Method: Hearing-related data were collected for 133 individuals with SMS aged 1-49 years. Audiogram data (97 participants) were used for cross-sectional and longitudinal analyses. Caregivers completed a sound sensitivity survey for 98 individuals with SMS and a control group of 24 unaffected siblings...
April 4, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28382131/superior-semicircular-canal-dehiscence-syndrome-diagnosis-and-surgical-management
#13
Marite Palma Diaz, Juan Carlos Cisneros Lesser, Alfredo Vega Alarcón
Introduction Superior semicircular canal dehiscence syndrome was described by Minor et al in 1998. It is a troublesome syndrome that results in vertigo and oscillopsia induced by loud sounds or changes in the pressure of the external auditory canal or middle ear. Patients may present with autophony, hyperacusis, pulsatile tinnitus and hearing loss. When symptoms are mild, they are usually managed conservatively, but surgical intervention may be needed for patients with debilitating symptoms. Objective The aim of this manuscript is to review the different surgical techniques used to repair the superior semicircular canal dehiscence...
April 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28286368/a-sound-therapy-based-intervention-to-expand-the-auditory-dynamic-range-for-loudness-among-persons-with-sensorineural-hearing-losses-case-evidence-showcasing-treatment-efficacy
#14
REVIEW
Craig Formby, LaGuinn P Sherlock, Monica L Hawley, Susan L Gold
Case evidence is presented that highlights the clinical relevance and significance of a novel sound therapy-based treatment. This intervention has been shown to be efficacious in a randomized controlled trial for promoting expansion of the dynamic range for loudness and increased sound tolerance among persons with sensorineural hearing losses. Prior to treatment, these individuals were unable to use aided sound effectively because of their limited dynamic ranges. These promising treatment effects are shown in this article to be functionally significant, giving rise to improved speech understanding and enhanced hearing aid benefit and satisfaction, and, in turn, to enhanced quality of life posttreatment...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28286367/structured-counseling-for-auditory-dynamic-range-expansion
#15
REVIEW
Susan L Gold, Craig Formby
A structured counseling protocol is described that, when combined with low-level broadband sound therapy from bilateral sound generators, offers audiologists a new tool for facilitating the expansion of the auditory dynamic range (DR) for loudness. The protocol and its content are specifically designed to address and treat problems that impact hearing-impaired persons who, due to their reduced DRs, may be limited in the use and benefit of amplified sound from hearing aids. The reduced DRs may result from elevated audiometric thresholds and/or reduced sound tolerance as documented by lower-than-normal loudness discomfort levels (LDLs)...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28286365/auditory-brainstem-and-middle-latency-responses-measured-pre-and-posttreatment-for-hyperacusic-hearing-impaired-persons-successfully-treated-to-improve-sound-tolerance-and-to-expand-the-dynamic-range-for-loudness-case-evidence
#16
REVIEW
Craig Formby, Peggy Korczak, LaGuinn P Sherlock, Monica L Hawley, Susan Gold
In this report of three cases, we consider electrophysiologic measures from three hyperacusic hearing-impaired individuals who, prior to treatment to expand their dynamic ranges for loudness, were problematic hearing aid candidates because of their diminished sound tolerance and reduced dynamic ranges. Two of these individuals were treated with structured counseling combined with low-level broadband sound therapy from bilateral sound generators and the third case received structured counseling in combination with a short-acting placebo sound therapy...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28286099/tinnitus-and-hyperacusis-contributions-of-paraflocculus-reticular-formation-and-stress
#17
Yu-Chen Chen, Guang-Di Chen, Benjamin D Auerbach, Senthilvelan Manohar, Kelly Radziwon, Richard Salvi
Tinnitus and hyperacusis are common and potentially serious hearing disorders associated with noise-, age- or drug-induced hearing loss. Accumulating evidence suggests that tinnitus and hyperacusis are linked to excessive neural activity in a distributed brain network that not only includes the central auditory pathway, but also brain regions involved in arousal, emotion, stress and motor control. Here we examine electrophysiological changes in two novel non-auditory areas implicated in tinnitus and hyperacusis: the caudal pontine reticular nucleus (PnC), involved in arousal, and the paraflocculus lobe of the cerebellum (PFL), implicated in head-eye coordination and gating tinnitus and we measure the changes in corticosterone stress hormone levels...
June 2017: Hearing Research
https://www.readbyqxmd.com/read/28277857/usefulness-of-self-report-questionnaires-for-psychological-assessment-of-patients-with-tinnitus-and-hyperacusis-and-patients-views-of-the-questionnaires
#18
Hashir Aazh, Brian C J Moore
OBJECTIVE: The objective was to determine the relevance and applicability of psychological questionnaires to patients seeking help for tinnitus and/or hyperacusis. DESIGN: This was a questionnaire-based survey. The following questionnaires were administered: Generalised Anxiety Disorder (GAD-7), Short Health Anxiety Inventory (SHAI), Mini-Social Phobia Inventory (Mini-SPIN), Obsessive Compulsive Inventory-Revised (OCI-R), Panic Disorder Severity Scale-Self Report (PDSS-SR), Patient Health Questionnaire (PHQ-9) and Penn State Worry Questionnaire-Abbreviated version (PSWQ-A)...
March 9, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28252196/health-relevant-personality-is-associated-with-sensitivity-to-sound-hyperacusis
#19
Karin Villaume, Dan Hasson
Hyperacusis, over-sensitivity to sounds, causes distress and disability and the etiology is not fully understood. The study aims to explore possible associations between health-relevant personality traits and hyperacusis. Hyperacusis was assessed using the Hyperacusis Questionnaire (HQ), and clinical uncomfortable loudness levels (ULL). Personality was measured with the Health-relevant Personality (HP5i) Inventory. The study sample was 348 (140 men and 208 women; age 23-71 years). Moderate correlations were found between the personality trait negative affectivity (NA; a facet of neuroticism) and dimensions of the HQ and weak correlations were found with the ULLs...
April 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28087419/cochlear-synaptopathy-in-acquired-sensorineural-hearing-loss-manifestations-and-mechanisms
#20
REVIEW
M Charles Liberman, Sharon G Kujawa
Common causes of hearing loss in humans - exposure to loud noise or ototoxic drugs and aging - often damage sensory hair cells, reflected as elevated thresholds on the clinical audiogram. Recent studies in animal models suggest, however, that well before this overt hearing loss can be seen, a more insidious, but likely more common, process is taking place that permanently interrupts synaptic communication between sensory inner hair cells and subsets of cochlear nerve fibers. The silencing of affected neurons alters auditory information processing, whether accompanied by threshold elevations or not, and is a likely contributor to a variety of perceptual abnormalities, including speech-in-noise difficulties, tinnitus and hyperacusis...
June 2017: Hearing Research
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