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https://www.readbyqxmd.com/read/29676141/-design-and-implementation-of-xinshenghua-granule-traceability-system-based-on-data-authenticity
#1
Zi-Bo Shen, Yang Lu, Sheng-Liang Huang, Chong Liu, Cun-Yu Li, Yun-Feng Zheng, Guo-Ping Peng
The quality of traditional Chinese medicine affects the clinical efficacy and the market research at home or abroad, which is closely related to the standardization of production. At present, Chinese market still exist in drug quality and nonstandard production phenomenon. In addition to the existing GMP production standards, it is still necessary to ensure the authenticity and reliability of traditional Chinese medicine by means of retrospect. Based on the Xinshenghua granule, starting from the authenticity of the whole process of production, this study designs and constructs the traditional Chinese medicine traceability system which is equipped with the Internet platform by using two-dimensional code as a trace tool...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29674799/assessment-of-nonsteroidal-anti-inflammatory-drug-use-pattern-using-world-health-organization-indicators-a-cross-sectional-study-in-a-tertiary-care-teaching-hospital-of-chhattisgarh
#2
P R R Vaishnavi, Nitin Gaikwad, S P Dhaneria
OBJECTIVE: The objective of this study is to assess drug utilization pattern of nonsteroidal anti-inflammatory drugs (NSAIDs) in a tertiary care teaching hospital, Raipur, Chhattisgarh. MATERIALS AND METHODS: A prospective, cross-sectional observational study was conducted in the outpatient department during 2-month period. After informed consent, the patients visiting pharmacy shop with a prescription were enrolled in the study. Their demographic details and prescription data were recorded in a case record form...
November 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29673600/online-drug-information-platform-for-the-public-in-hong-kong-review-of-local-drug-information-use-and-needs
#3
F W T Cheng, S W K So, B W T Fung, W H Hung, V W Y Lee
INTRODUCTION: In view of the popularity of Internet usage in Hong Kong, an interactive web-based drug information platform entitled "Ask My Pharmacist - Online University Led drug Enquiry Platform" (AMPOULE) was launched in 2009 to better serve the needs of drug information in Hong Kong. This paper aimed to evaluate the utility of AMPOULE in improving drug-related knowledge among the public and to reassess the needs of the general public in Hong Kong. METHODS: All enquiries sent via AMPOULE were reviewed...
June 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29666228/deep-learning-improves-prediction-of-drug-drug-and-drug-food-interactions
#4
Jae Yong Ryu, Hyun Uk Kim, Sang Yup Lee
Drug interactions, including drug-drug interactions (DDIs) and drug-food constituent interactions (DFIs), can trigger unexpected pharmacological effects, including adverse drug events (ADEs), with causal mechanisms often unknown. Several computational methods have been developed to better understand drug interactions, especially for DDIs. However, these methods do not provide sufficient details beyond the chance of DDI occurrence, or require detailed drug information often unavailable for DDI prediction. Here, we report development of a computational framework DeepDDI that uses names of drug-drug or drug-food constituent pairs and their structural information as inputs to accurately generate 86 important DDI types as outputs of human-readable sentences...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29663572/a-review-of-studies-evaluating-the-effectiveness-of-risk-minimisation-measures-in-europe-using-the-european-union-electronic-register-of-post-authorization-studies
#5
REVIEW
Pareen Vora, Esther Artime, Montse Soriano-Gabarró, Nawab Qizilbash, Vineet Singh, Alex Asiimwe
PURPOSE: An important element of risk management is the planning and implementation of risk minimisation measures (RMMs) and the evaluation of their effectiveness by process or outcome indicators. The aim of this review is to summarize the characteristics of risk minimisation (RM) effectiveness studies in Europe and provide an overview of RMMs and their effectiveness. METHODS: This was a qualitative review of RM effectiveness studies in the European Union electronic Register of Post-Authorization Studies (EU PAS Register); data extracted included study design, population, sample size, data sources, drug information, RMMs, study period, indicators, and their reported effectiveness...
April 16, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29651437/questions-frequently-asked-of-healthcare-professionals-a-2-year-data-survey-conducted-at-a-medical-center
#6
Chi-Lien Hou, Ying-Hao Lu, Shun-Ching Chien, Hsu-Hui Chen, Chung-Yu Chen
In this descriptive, retrospective study, we analyzed the types of questions posed by healthcare professionals to drug counselors at a medical center and the types of provision of pharmaceutical advice solicited to improve pharmaceutical care quality and establish clear directions for clinical pharmacist training. We collected 8,558 questions posed by healthcare professionals (physicians, 38%; pharmacists, 39%; nurses, 23%) from the electronic drug information record system from May 2013 to April 2015 in one medical center...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29619140/challenges-and-opportunities-of-clinical-pharmacy-services-in-ethiopia-a-qualitative-study-from-healthcare-practitioners-perspective
#7
Henok G Tegegn, Ousman A Abdela, Abebe B Mekuria, Akshaya S Bhagavathula, Asnakew A Ayele
Background: Currently, clinical pharmacists have in-depth therapeutic knowledge and scientific skills to act as drug therapy experts in healthcare settings. Objective: The aim of this study was to assess the opportunities and challenges of clinical pharmacy services from the health practitioners' perspective in University of Gondar (UOG) hospital Ethiopia. Methods: A qualitative study was performed using face-to-face in-depth interviews with health practitioners who were directly involved in clinical pharmacy services (clinical pharmacists, physicians, and nurses) in UOG hospital...
January 2018: Pharmacy Practice
https://www.readbyqxmd.com/read/29592848/consumer-mobile-apps-for-potential-drug-drug-interaction-check-systematic-review-and-content-analysis-using-the-mobile-app-rating-scale-mars
#8
REVIEW
Ben Yb Kim, Anis Sharafoddini, Nam Tran, Emily Y Wen, Joon Lee
BACKGROUND: General consumers can now easily access drug information and quickly check for potential drug-drug interactions (PDDIs) through mobile health (mHealth) apps. With aging population in Canada, more people have chronic diseases and comorbidities leading to increasing numbers of medications. The use of mHealth apps for checking PDDIs can be helpful in ensuring patient safety and empowerment. OBJECTIVE: The aim of this study was to review the characteristics and quality of publicly available mHealth apps that check for PDDIs...
March 28, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29589473/evaluation-of-point-of-care-resources-for-dietary-supplement-information
#9
Ashley E Montgomery, Robert D Beckett, Kaitlin J Montagano, Samah Kutom
OBJECTIVE: To evaluate 6 tertiary, point-of-care drug information resources' dietary supplement content. METHODS: This was a cross-sectional evaluation of Lexicomp Natural Products Database, Micromedex Alternative Medicine, Clinical Pharmacology, Natural Medicines, The Review of Natural Products, and Handbook of Nonprescription Drugs. Each resource was evaluated for scope, completeness, consistency, and ease of use. RESULTS: For a sample of 66 supplements, scope scores ranged from 69...
January 2018: Journal of evidence-based integrative medicine
https://www.readbyqxmd.com/read/29579074/prevalence-and-determinants-of-self-medication-practice-among-selected-households-in-addis-ababa-community
#10
Mensur Shafie, Mebrahtu Eyasu, Kedija Muzeyin, Yoseph Worku, Sagrario Martín-Aragón
BACKGROUND AND AIM: Self-medication (SM) is one part of self-care which is known to contribute to primary health care. If practiced appropriately, it has major benefits for the consumers such as self-reliance and decreased expense. However, inappropriate practice can have potential dangers such as incorrect self-diagnosis, dangerous drug-drug interactions, incorrect manner of administration, incorrect dosage, incorrect choice of therapy, masking of a severe disease, and/or risk of dependence and abuse...
2018: PloS One
https://www.readbyqxmd.com/read/29567847/reliability-of-coded-data-to-identify-earliest-indications-of-cognitive-decline-cognitive-evaluation-and-alzheimer-s-disease-diagnosis-a-pilot-study-in-england
#11
Grazia Dell'Agnello, Urvi Desai, Noam Y Kirson, Jody Wen, Mark K Meiselbach, Catherine C Reed, Mark Belger, Alan Lenox-Smith, Carlos Martinez, Jill Rasmussen
OBJECTIVES: Evaluate the reliability of using diagnosis codes and prescription data to identify the timing of symptomatic onset, cognitive assessment and diagnosis of Alzheimer's disease (AD) among patients diagnosed with AD. METHODS: This was a retrospective cohort study using the UK Clinical Practice Research Datalink (CPRD). The study cohort consisted of a random sample of 50 patients with first AD diagnosis in 2010-2013. Additionally, patients were required to have a valid text-field code and a hospital episode or a referral in the 3 years before the first AD diagnosis...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29553427/acute-poisoning-in-the-gaza-strip-a-retrospective-study
#12
Mohammed K El-Habil
BACKGROUND: Acute poisoning is a major public health problem worldwide and a common cause of patient admissions to emergency departments and intensive care units. The aim of this study was to assess the acute poisoning cases admitted to three hospitals in the Gaza Strip and to assess the need for a poison control and drug information centre in the Gaza Strip. METHODS: All patients diagnosed with acute poisoning between 2010 and 2015 at the emergency departments of Al-Shifa Hospital, European Gaza Hospital, and Al-Nassr Paediatric Hospital in the Gaza Strip were included in this retrospective study...
February 21, 2018: Lancet
https://www.readbyqxmd.com/read/29545755/exploration-of-the-anti-inflammatory-drug-space-through-network-pharmacology-applications-for-drug-repurposing
#13
Guillermo de Anda-Jáuregui, Kai Guo, Brett A McGregor, Junguk Hur
The quintessential biological response to disease is inflammation. It is a driver and an important element in a wide range of pathological states. Pharmacological management of inflammation is therefore central in the clinical setting. Anti-inflammatory drugs modulate specific molecules involved in the inflammatory response; these drugs are traditionally classified as steroidal and non-steroidal drugs. However, the effects of these drugs are rarely limited to their canonical targets, affecting other molecules and altering biological functions with system-wide effects that can lead to the emergence of secondary therapeutic applications or adverse drug reactions (ADRs)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29534349/most-effective-pain-control-procedure-for-open-liver-surgery-a-network-meta-analysis
#14
REVIEW
Ling Zhou, Jian Huang, Changwang Chen
BACKGROUND: To determine the most effective pain-control procedure for open liver surgery through a network meta-analysis and provide a best developing direction in this field. METHODS: PubMed, Embase and Cochrane Library database were searched for randomized controlled trials up to 1 July 2016. We extracted data on post-operative pain score at the 4th-8th hour and 24th hour from studies that compared various pain-control strategies. Network meta-analysis was conducted in Aggregate Data Drug Information System software by evaluating the parametric pain score at rest and on movement...
March 13, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29527829/determination-of-nursing-students-attitudes-towards-the-use-of-technology
#15
Nurten Terkes, Ferya Celik, Hicran Bektas
AIM: The use of technology is increasingly important in nursing education and practice. For this reason, it is necessary to determine the attitudes of nursing students towards technology. METHODS: This study was conducted with 508 nursing students. A personal information form that was prepared by the researchers and the Attitudes Toward Technology Scale were used as the data collection tools. RESULTS: The mean score that was obtained by the nursing students from the Attitudes Toward Technology Scale was 61...
March 11, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29503426/-quantitative-prediction-of-drug-drug-interaction-caused-by-cyp-inhibition-and-induction-from-in-vivo-data-and-its-application-in-daily-clinical-practices-proposal-for-the-pharmacokinetic-interaction-significance-classification-system-piscs
#16
Yoshiyuki Ohno
 Drug-drug interactions (DDIs) can affect the clearance of various drugs from the body; however, these effects are difficult to sufficiently evaluate in clinical studies. This article outlines our approach to improving methods for evaluating and providing drug information relative to the effects of DDIs. In a previous study, total exposure changes to many substrate drugs of CYP caused by the co-administration of inhibitor or inducer drugs were successfully predicted using in vivo data. There are two parameters for the prediction: the contribution ratio of the enzyme to oral clearance for substrates (CR), and either the inhibition ratio for inhibitors (IR) or the increase in clearance of substrates produced by induction (IC)...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29503423/-current-status-and-issues-of-electronic-information-provision-for-risk-minimization-coordination-between-electronic-medicine-notebook-and-patient-drug-information
#17
Takao Orii
 In the collaboration between community pharmacies and hospitals or clinics, the use of electronic medicine notebook may allow information sharing, including among out-of-network hospitals, clinics, and community pharmacies. For risk minimization, mobile or smart phones, which patients always carry with them, should be used as a tool allowing drug information to be accessed at any time. An advantage of the electronic conversion of patient drug information is that it allows patients not only to obtain round-the-clock information on drugs, etc...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29503420/-risk-benefit-communication-international-developments-and-prospects-for-the-future
#18
Michiko Yamamoto
 While expectations for the benefits of pharmaceuticals are high, the occurrence of health damage from adverse drug reactions remains a problem. One of the reasons for this seems to be insufficient risk communication among stakeholders. Healthcare professionals (HCPs), relevant agencies, and pharmaceutical companies have responsibilities to communicate useful information on the risks/benefits of the pharmaceuticals they provide in addition to basic policies and services. Four years have passed since the risk management plan system was introduced in Japan...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29498322/navigating-manuscript-assessment-the-new-practitioner-s-guide-to-primary-literature-peer-review
#19
Devlin V Smith, Laura B Stokes, Kayleigh Marx, Samuel L Aitken
For pharmacists, the first years after graduation are spent developing their knowledge base, advancing as a practitioner, and honing their abilities as healthcare providers and drug information experts. New practitioners encounter many challenges during this time, which for many include publishing original research or reviewing manuscripts for colleagues and medical journals. Inexperience navigating the publication process, from submission to receipt of (and response to) peer review commentary, is often cited as a major barrier to timely publication of resident and new practitioner research...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29491499/impact-of-spacing-of-practice-on-learning-brand-name-and-generic-drugs
#20
James Terenyi, Heidi Anksorus, Adam M Persky
Objective. To test the impact of schedules of retrieval practice on learning brand and generic name drug information in a self-paced course. Methods. Students completed weekly quizzes on brand and generic name conversions for 100 commonly prescribed drugs. Each student completed part of the drug list on a schedule of equal, expanding, or contracting spacing, one practice (massed) or study only in a partial block design. Results. On measures of long-term retention, the contracting spacing schedule led to superior retention (67%) compared to the massed practice (50%) and study-only condition (46%); contracting practice also was significantly higher than expanding practice (58%,) or equal practice (59%)...
February 2018: American Journal of Pharmaceutical Education
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