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https://www.readbyqxmd.com/read/29035337/role-of-information-anxiety-and-information-load-on-processing-of-prescription-drug-information-leaflets
#1
Shweta S Bapat, Harshali K Patel, Sujit S Sansgiry
In this study, we evaluate the role of information anxiety and information load on the intention to read information from prescription drug information leaflets (PILs). These PILs were developed based on the principals of information load and consumer information processing. This was an experimental prospective repeated measures study conducted in the United States where 360 (62% response rate) university students (>18 years old) participated. Participants were presented with a scenario followed by exposure to the three drug product information sources used to operationalize information load...
October 16, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29032849/mapping-the-landscape-of-patient-centric-activities-within-clinical-research
#2
Mary Jo Lamberti, Josephine Awatin
PURPOSE: Although there has been more involvement by patients in the drug-development process, there are not a lot of published data that quantify patient-centric activities or that document these activities across a large scale. In order to examine the patient-centricity landscape and to quantify the adoption and implementation of these initiatives, the Tufts Center for the Study of Drug Development and the Drug Information Association collaborated on a research study. The study examined patient-centric activities implemented by pharmaceutical, biotechnology, and contract research organizations, as well as activities being piloted or in the planning stages...
October 9, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29029665/mohs-micrographic-surgery-key-pharmacologic-considerations
#3
Diana Fischer, Patricia Orlando, Laura Shane-McWhorter
OBJECTIVE: To describe Mohs micrographic surgery and evaluate whether direct oral anticoagulants should be withheld in patients with atrial fibrillation (Afib) prior to the procedure and to consider what type of antibiotic prophylaxis should be used. SETTING: A community setting in which an elderly patient is living independently at home. PRACTICE DESCRIPTION: Academic-affiliated internal medicine clinic that cares for adult patients of all ages, including elderly patients living independently in their own home...
August 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29029375/treatment-and-disease-management-of-multiple-sclerosis-patients-a-review-for-nurse-practitioners
#4
Cortnee Roman, Kara Menning
BACKGROUND AND PURPOSE: This review discusses the role of the nurse practitioner (NP) in evaluating the clinical effects, potential side effects, and monitoring requirements for treatment options in multiple sclerosis (MS) and provides guidance on how to help patients understand these issues. METHODS: A literature search was conducted on PubMed to identify publications on monitoring and disease management of MS patients. Additional resources included drug information web sites and package inserts...
October 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29028228/preventing-emergence-of-drug-resistant-tuberculosis-in-myanmar-s-transitioning-health-system
#5
Mishal S Khan, Coll Hutchison, Richard J Coker, Joanne Yoong, Khaung M Hane, Anh L Innes, Tin M Khaing, Sithu Aung
Multidrug-resistant tuberculosis (MDR-TB) is a particular threat to the populations of resource-limited countries. Although inadequate treatment of TB has been identified as a major underlying cause of drug resistance, essential information to inform changes in health service delivery and policy is missing. We investigate factors that may be driving the emergence of MDR-TB in Myanmar, a country where investment and health system reforms are ongoing to address the unexplained, high occurrence of MDR-TB. We conducted a multi-centre, retrospective case-control study in 10 townships across Yangon...
October 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29026844/an-interprofessional-collaboration-between-medicine-and-pharmacy-schools-designing-and-evaluating-a-teaching-program-on-practical-prescribing
#6
Mohammad Reza Javadi, Mina Khezrian, Anahita Sadeghi, Seyed Hossein Hajimiri, Kaveh Eslami
OBJECTIVE: Medical students need proper education in drug prescription. The aim of the present study is to introduce a course that improves the students' prescribing skills and also promotes an interprofessional collaboration between medicine and pharmacy schools. METHODS: This study was done in a skill laboratory at the pharmacotherapy department of Tehran University of Medical Sciences, Tehran, Iran. The course was an 18-h interactive workshop in 3 days under the supervision of clinical pharmacists...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29021111/exploring-mortality-among-drug-treatment-clients-the-relationship-between-treatment-type-and-mortality
#7
Belinda Lloyd, Renee Zahnow, Monica J Barratt, David Best, Dan I Lubman, Jason Ferris
AIMS: Studies consistently identify substance treatment populations as more likely to die prematurely compared with age-matched general population, with mortality risk higher out-of-treatment than in-treatment. While opioid-using pharmacotherapy cohorts have been studied extensively, less evidence exists regarding effects of other treatment types, and clients in treatment for other drugs. This paper examines mortality during and following treatment across treatment modalities. METHODS: A retrospective seven-year cohort was utilised to examine mortality during and in the two years following treatment among clients from Victoria, Australia, recorded on the Alcohol and Drug Information Service database by linking with National Death Index...
November 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28978832/clinical-sequencing-in-leukemia-with-the-assistance-of-artificial-intelligence
#8
Arinobu Tojo
Next generation sequencing (NGS) of cancer genomes is now becoming a prerequisite for accurate diagnosis and proper treatment in clinical oncology. Because the genomic regions for NGS expand from a certain set of genes to the whole exome or whole genome, the resulting sequence data becomes incredibly enormous and makes it quite laborious to translate the genomic data into medicine, so-called annotation and curation. We organized a clinical sequencing team and established a bidirectional (bed-to-bench and bench-to-bed) system to integrate clinical and genomic data for hematological malignancies...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/28975584/overview-of-pharmacovigilance-system-in-vietnam-lessons-learned-in-a-resource-restricted-country
#9
Khac-Dung Nguyen, Phuong-Thuy Nguyen, Hoang-Anh Nguyen, Anne Roussin, Jean-Louis Montastruc, Haleh Bagheri, Sten Olsson
Drug safety issues in developing countries are complex and sensitive, and health authorities cannot always simply implement decisions from developed countries because the health system, disease patterns, and lists of marketed drugs all differ. A system for proactive and effective surveillance of drugs in each nation is needed to identify and manage the exact drug-related problems faced by patients in these countries. Vietnam launched its university-based National Drug Information and Adverse Drug Reaction Monitoring Centre (NDIADRMC) in 2009, a significant step towards catching up with international trends...
October 3, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28970611/improving-pharmacy-student-communication-outcomes-using-standardized-patients
#10
Chris Gillette, Michael Rudolph, Nicole Rockich-Winston, Robert Stanton, H Glenn Anderson
Objective. To examine whether standardized patient encounters led to an improvement in a student pharmacist-patient communication assessment compared to traditional active-learning activities within a classroom setting. Methods. A quasi-experimental study was conducted with second-year pharmacy students in a drug information and communication skills course. Student patient communication skills were assessed using high-stakes communication assessment. Results. Two hundred and twenty students' data were included...
August 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28970463/prevalence-of-self-medication-among-students-of-pharmacy-and-medicine-colleges-of-a-public-sector-university-in-dammam-city-saudi-arabia
#11
Fatimah Ali Albusalih, Atta Abbas Naqvi, Rizwan Ahmad, Niyaz Ahmad
Pharmacy and medical students are expected to be more knowledgeable regarding rational use of medications as compared to the general public. A cross-sectional study was conducted among students of pharmacy and medicine colleges of Imam Abdulrahman Bin Faisal University in Dammam, Saudi Arabia using a survey questionnaire. The duration of the study was six months. The aim was to report self-medication prevalence of prescription and non-prescription drugs among pharmacy and medical students. The prevalence of self-medication in the pharmacy college was reported at 19...
September 4, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28970449/assessment-of-drug-information-service-in-public-and-private-sector-tertiary-care-hospitals-in-the-eastern-province-of-saudi-arabia
#12
Sawsan Abdullah Alamri, Raniah Ali Al Jaizani, Atta Abbas Naqvi, Mastour Safer Al Ghamdi
Drug information service is a dedicated and specialized service provided by pharmacists to enhance knowledge of medicines use, promote rational prescribing among prescribers, and reduce medication errors. Saudi Arabia has a National Drug and Poison Information Center (NDPIC) responsible for answering drug queries. There is a lack of literature that reports the current scenario of drug information services in the country, especially the Eastern Province. This study reported the current status of drug information services being provided among tertiary care hospitals of the Eastern Province of Saudi Arabia...
July 4, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28970246/u-s-vaccine-and-immune-globulin-product-shortages-2001-15
#13
Victoria C Ziesenitz, Maryann Mazer-Amirshahi, Mark S Zocchi, Erin R Fox, Larissa S May
PURPOSE: Trends in shortages of vaccines and immune globulin products from 2001 through 2015 in the United States are described. METHODS: Drug shortage data from January 2001 through December 2015 were obtained from the University of Utah Drug Information Service. Shortage data for vaccines and immune globulins were analyzed, focusing on the type of product, reason for shortage, shortage duration, shortages requiring vaccine deferral, and whether the drug was a single-source product...
October 2, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28951876/the-needs-and-resources-of-drug-information-at-community-pharmacies-in-gondar-town-northwest-ethiopia
#14
Dessalegn Asmelashe Gelayee, Gashaw Binega Mekonnen, Mequanent Kassa Birarra
BACKGROUND: Community pharmacists are in a key position to provide information on drugs and thus promote the rational use of drugs. OBJECTIVES: The present study was designed to determine the needs and resources of drug information in community pharmacies. METHODS: A prospective institution based cross-sectional study was carried out and data were collected on 48 community pharmacists in Gondar, Northwest Ethiopia, using interviewer administered structured questionnaire...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28947434/discrepancies-in-drug-histories-at-admission-to-gastrointestinal-surgery-internal-medicine-and-geriatric-hospital-wards-in-central-norway-a-cross-sectional-study
#15
Janne Kutschera Sund, Olav Sletvold, Trude Cecilie Mellingsæter, Randi Hukari, Torstein Hole, Per Einar Uggen, Petra Thiemann Vadset, Olav Spigset
OBJECTIVES: To compare discrepancies in drug histories among patients acutely admitted to different hospital wards, classify the discrepancies according to their potential clinical impact and identify appropriate selection criteria for patients that should be subject to a detailed drug history at admission. DESIGN: Cross-sectional study. SETTING: Two gastrointestinal surgery wards and one geriatric ward at St Olav's University Hospital in Trondheim and two general internal medicine wards at Ålesund Hospital in Ålesund, Norway...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28947411/information-about-medications-in-the-district-of-bamako-mali
#16
M Koné, T Diallo, A Dénou, B F Coulibaly, B Dackouo, B Coulibaly, B Y Koumaré, A Maiga
The aim of our study was to investigate the quality of information about pharmaceutical products in Mali. The study surveyed 98 prescribers, 60 pharmacists, and the package inserts of a basket of 30 generic medicines, compared to those of the corresponding proprietary versions. We made a rational choice of 98 doctors from various specialties and levels of the health system and randomly selected 60 of the 215 pharmacies in the district of Bamako (Mali). A rational sampling of generic medicines provided us with a basket of 30 drug notices for the antimalarial, antibiotic, antalgic, antipyretic, and anti-inflammatory agents used most in the Republic of Mali...
August 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28944731/the-fda-unapproved-drugs-initiative-an-observational-study-of-the-consequences-for-drug-prices-and-shortages-in-the-united-states
#17
Ravi Gupta, Sanket S Dhruva, Erin R Fox, Joseph S Ross
BACKGROUND: Hundreds of drug products are currently marketed in the United States without approval from the FDA. The 2006 Unapproved Drugs Initiative (UDI) requires manufacturers to remove these drug products from the market or obtain FDA approval by demonstrating evidence of safety and efficacy. Once the FDA acts against an unapproved drug, fewer manufacturers remain in the market, potentially enabling drug price increases and greater susceptibility to drug shortages. There is a need for systematic study of the UDI's effect on prices and shortages of all targeted drugs...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28929445/physicians-questions-concerning-drug-use-among-older-patients-experience-from-norwegian-drug-information-centres-relis-in-the-period-2010-2015
#18
Jan Schjøtt
Questions from physicians to regional medicines information and pharmacovigilance centres in Norway (RELIS) concerning older patients were described. Question-answer pairs (QAPs) from the RELIS database indexed with the category "older", and concerning individual patients from the period 01 Jan 2010 to 31 Dec 2015, were analysed. Two-hundred and eight QAPs categorized with "older" were retrieved from a total of 16 710 in the study period, and 122 of 208 QAPs fulfilled the inclusion criteria. The most common categories of drugs in question (n = 228) according to the ATC system were N: Nervous system (30...
September 19, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28918098/identifying-novel-factor-xiia-inhibitors-with-pca-ga-svm-developed-vhts-models
#19
Jonathan Jun Feng Chen, Donald P Visco
There currently is renewed interest in blood clotting Factor XII as a potential target for thrombosis inhibition. Historically untargeted, there is little drug information with which to start drug candidate searches. Typical high-throughput screening can identify potential drug candidates, but is inefficient. Virtual high-throughput screening can be used to raise efficiency by focusing experimental efforts on compounds predicted to be active and is applied here to identify new Factor XIIa inhibitors. We combine principal component analysis, genetic algorithm and support vector machine to create the models used in the virtual high-throughput screening...
September 1, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28913813/pharmacotherapy-pearls-for-emergency-neurological-life-support
#20
Gretchen M Brophy, Theresa Human
The appropriate use of medications during Emergency Neurological Life Support (ENLS) is essential to optimize patient care. Important considerations when choosing the appropriate agent include the patient's organ function and medication allergies, potential adverse drug effects, drug interactions and critical illness and aging pathophysiologic changes. Critical medications used during ENLS include hyperosmolar therapy, anticonvulsants, antithrombotics, anticoagulant reversal and hemostatic agents, anti-shivering agents, neuromuscular blockers, antihypertensive agents, sedatives, vasopressors and inotropes, and antimicrobials...
September 14, 2017: Neurocritical Care
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