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Otitis media effusion

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https://www.readbyqxmd.com/read/28340091/effect-of-antimicrobial-treatment-on-the-resolution-of-middle-ear-effusion-after-acute-otitis-media
#1
Aino Ruohola, Miia K Laine, Paula A Tähtinen
Background.: Acute otitis media (AOM) induces middle-ear effusion (MEE), which affects hearing. The effect of antimicrobial treatment on the resolution of MEE is controversial, and the factors that affect resolution are unknown. Methods.: We studied the effect of antimicrobial treatment on the time to the resolution of MEE as a secondary objective in our randomized double-blind placebo-controlled trial. Children aged 6 to 35 months with stringently diagnosed AOM were allocated to receive amoxicillin-clavulanate (161 patients) or placebo (158 patients) for 7 days and closely followed for 3 months...
March 16, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28325168/impact-of-pharyngofixation-in-cleft-palate-repair-surgery-on-the-development-of-chronic-adhesive-otitis-media
#2
L Otruba, P Schalek, Z Hornáčková
BACKGROUND: A significant percentage of children with cleft palate suffer from otitis media with effusion and its consequences, such as deafness, chronic adhesive otitis and cholesteatoma. This study aimed to determine whether these effects can be minimised by selecting pharyngofixation as the surgical technique for cleft palate correction. METHODS: A retrospective study was performed of 155 patients (308 ears) who underwent surgery from age 5 months to 8 years and were followed up for 36-84 months...
March 22, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28290230/cilia-and-ear
#3
Gioia Piatti, Maria Margherita De Santi, Sara Torretta, Lorenzo Pignataro, Daniela Soi, Umberto Ambrosetti
OBJECTIVE: To investigate the prevalence of otological complications derived from primary ciliary dyskinesia (PCD) in adulthood. METHODS: Twenty-three patients with diagnosed PCD underwent medical history aimed at recording the presence of ear, nose, and throat manifestations (ENT) and any surgical treatments. The ENT objectivity was annotated, and then patients were subjected to audiometric test, tympanometry, registration of otoacoustic emission, and vestibular evaluation...
April 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28283791/balloon-eustachian-tuboplasty-in-children
#4
A Leichtle, D Hollfelder, B Wollenberg, K-L Bruchhage
Endonasal ballon dilatation of the Eustachian tube (BET) is a promising treatment for Eustachian tube dysfunction with encouraging results over the last years in adults. In addition, in children, single studies demonstrated promising results, but revealed the necessity for broader and additional studies. Our retrospective analysis presents outcomes with BET in children with chronic obstructive dysfunction of the Eustachian tube, showing resistance to the conventional therapy after adenotomy with paracentesis or grommets (ventilation tubes)...
March 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28244296/bacterial-species-and-antibiotic-sensitivity-in-korean-patients-diagnosed-with-acute-otitis-media-and-otitis-media-with-effusion
#5
Sang Hoon Kim, Eun Ju Jeon, Seok Min Hong, Chang Hoon Bae, Ho Yun Lee, Moo Kyun Park, Jae Yong Byun, Myung Gu Kim, Seung Geun Yeo
Changes over time in pathogens and their antibiotic sensitivity resulting from the recent overuse and misuse of antibiotics in otitis media (OM) have complicated treatment. This study evaluated changes over 5 years in principal pathogens and their antibiotic sensitivity in patients in Korea diagnosed with acute OM (AOM) and OM with effusion (OME). The study population consisted of 683 patients who visited the outpatient department of otorhinolaryngology in 7 tertiary hospitals in Korea between January 2010 and May 2015 and were diagnosed with acute AOM or OME...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28231295/the-pathogens-profile-in-children-with-otitis-media-with-effusion-and-adenoid-hypertrophy
#6
G P Buzatto, E Tamashiro, J L Proenca-Modena, T H Saturno, M C Prates, T B Gagliardi, L R Carenzi, E T Massuda, M A Hyppolito, F C P Valera, E Arruda, W T Anselmo-Lima
OBJECTIVES: To evaluate the presence of viruses and bacteria in middle ear and adenoids of patients with and without otitis media with effusion (OME). METHODS: Adenoid samples and middle ear washes (MEW) were obtained from children with OME associated with adenoid hypertrophy undergoing adenoidectomy and tympanostomy, and compared to those obtained from patients undergoing cochlear implant surgery, as a control group. Specific DNA or RNA of 9 respiratory viruses (rhinovirus, influenza virus, picornavirus, syncytial respiratory virus, metapneumovirus, coronavirus, enterovirus, adenovirus and bocavirus) and 5 bacteria (S...
2017: PloS One
https://www.readbyqxmd.com/read/28229060/vitamin-d-levels-in-children-with-adenotonsillar-hypertrophy-and-otitis-media-with-effusion
#7
Alimohamad Asghari, Zohreh Bagheri, Maryam Jalessi, Mohammad Mahdi Salem, Elahe Amini, Sahand GhalehBaghi, Sepideh Bakhti
INTRODUCTION: Vitamin D has been suggested to play a considerable role in the function of the immune system in various infectious, inflammatory, and autoimmune conditions. Otitis media with effusion (OME), defined as the presence of non-purulent fluid within the middle ear without signs or symptoms of suppurative otitis media, has a number of inflammatory predisposing factors. This study was designed to explore the association between vitamin D deficiency and OME. MATERIALS AND METHODS: In this cross-sectional study, 74 children aged 2-7 years with an obstructive indication for adenotonsillectomy were included...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28167007/sinuclean-nebules-treatment-in-children-suffering-from-otitis-media-with-effusion
#8
A Varricchio, A De Lucia, A M Varricchio, A Della Volpe, N Mansi, V Pastore, G Ciprandi
OBJECTIVE: Otitis media with effusion (OME) is an ear disorder defined by the presence of fluid in the middle ear without signs or symptoms of acute infection. The current randomized, double-blind, controlled study aimed to evaluate whether Sinuclean Nebules treatment, administered by nasal douche (Rinowash), could induce ear healing better than isotonic saline in children with OME. METHODS: The study was randomized, double-blind, and controlled. Group A (30 children) was treated with Sinuclean Nebules 45 and Group B (31 children) was treated with isotonic saline; both compounds were administered by nasal nebulization with Rinowash nasal douche twice/day in the morning and in the evening for 10 days, followed by a one-week suspension, and after by a second course as the first...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28157838/purification-and-characterization-of-micrornas-within-middle-ear-fluid-exosomes-implication-in-otitis-media-pathophysiology
#9
Stéphanie Val, Stephanie Jeong, Marian Poley, Anna Krueger, Gustavo Nino, Kristy Brown, Diego Preciado
BACKGROUND: Otitis Media (OM) is characterized by acute infection progressing to chronic middle ear effusion (MEE). Extracellular secretion of microRNAs (miRNAs) in exosomes is a newly discovered mechanism for cells exerting distant cell genetic regulation. Whether MEE contains exosomes with specific miRNAs is unknown. This study aimed to purify and characterize the exosomal and miRNA content of MEE. METHOD: MEEs were subjected to Exoquick exosomal purification and EXOCET exosomal quantification...
February 3, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28141649/values-range-of-tympanometric-gradient-in-otitis-media-with-effusion
#10
Sertac Duzer, Oner Sakallioglu, Abdulvahap Akyigit, Cahit Polat, Hasan Cetiner, Nihat Susaman
INTRODUCTION: The aim of this study was to establish how reliable a given tympanogram is in predicting the presence or absence of a middle ear effusion, and to provide new views for the diagnostic information of tympanometry. The use of tympanometric gradient in addition to static admittance is the focus of this study. MATERIALS AND METHODS: The authors enrolled 146 female and 129 male patients. The participants were allocated into groups as follow: Group A1 consisted of 50 healthy children...
January 30, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28116997/the-burden-and-epidemiology-of-eustachian-tube-dysfunction-in-adults
#11
Peter M Vila, Tom Thomas, Carrie Liu, Dennis Poe, Jennifer J Shin
Objectives Pediatric eustachian tube dysfunction (ETD), otitis media with effusion (OME), and tympanic membrane retraction (TMR) have been well studied, but no large analyses have described the associated burden beyond childhood. The potential impact and feasibility of prospective trials designed to optimize management of affected adults are thus unclear. Our objectives were therefore (1) to determine the national visit burden associated with ETD/OME/TMR beyond childhood and (2) to examine risk factors specific to adults, highlighting differences in comparison with children...
February 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28109498/nasopharyngeal-radium-irradiation-the-lessons-of-history
#12
Kees Graamans
In the Netherlands, nasopharyngeal radium irradiation was started in 1945. The indications included refractory symptoms of otitis media with effusion and other adenoid-related disorders after adenoidectomy. It was considered a safe and effective therapy. Its use decreased sharply in 1958, following a worldwide media avalanche around the dramatic events in the treatment of a 5-year-old child in Utrecht, enhancing the widespread fear of radioactivity. This case history illustrates the powerful role of the media in medical decision-making...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28109489/impact-of-environmental-volatile-organic-compounds-on-otitis-media-in-children-correlation-between-exposure-and-urinary-metabolites
#13
So Young Kim, Bu-Soon Son, Hee-Jin Park, Seung Ha Oh, Jun Ho Lee, Myung-Hwan Suh, Moo Kyun Park
INTRODUCTION: Volatile organic compounds (VOCs) induce inflammatory responses. Tobacco smoke contains numerous VOCs and is a risk factor for otitis media effusion (OME); however, no previous studies have investigated the association between VOCs and OME. OBJECTIVES: We used urinary metabolites and exposure to environmental risk factors to investigate the association between VOC and polycyclic aromatic hydrocarbon exposure and recurrent OME in children. METHODS: Children with recurrent OME who visited the Otorhinolaryngology Department of Seoul National University Hospital between November 2014 and June 2015 were prospectively enrolled in the study...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28106700/the-predictive-value-of-neutrophil-lymphocyte-and-platelet-lymphocyte-ratio-for-the-effusion-viscosity-in-otitis-media-with-chronic-effusion
#14
Mustafa Suphi Elbistanli, Hasan Emre Koçak, Harun Acipayam, Ayşe Pelin Yiğider, Mehmet Keskin, Fatma Tülin Kayhan
OBJECTIVE: The objective of the authors' study was to investigate the predictive value of the neutrophil-lymphocyte rate (NLR) and platelet-lymphocyte rate (PLR) in otitis media with effusion and the correlation of the effusion type with these ratios. STUDY DESIGN: Retrospective case-control study. METHODS: One hundred twenty-six pediatric patients diagnosed otitis media with chronic effusion and had ventilation tube inserted between October 2015 and July 2016 were included in the study group and 124 healthy children, who applied for the routine examination and had blood count analysis, were included in the control group...
January 18, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28103950/the-effects-of-ventilation-tubes-versus-no-ventilation-tubes-for-recurrent-acute-otitis-media-or-chronic-otitis-media-with-effusion-in-9-to-36%C3%A2-month-old-greenlandic-children-the-siutit-trial-study-protocol-for-a-randomized-controlled-trial
#15
Malene Nøhr Demant, Ramon Gordon Jensen, Janus Christian Jakobsen, Christian Gluud, Preben Homøe
BACKGROUND: The prevalence of otitis media in Greenlandic children is one of the highest in the world. International studies have shown that otitis-prone children may benefit from tubulation of the tympanic membrane. However, it is unknown whether these results can be applied to Greenlandic children and trials on the effects of ventilation tubes in high-risk populations have, to our knowledge, never been conducted. METHODS: The trial is an investigator-initiated, multicentre, randomized, blinded superiority trial of bilateral ventilation tube insertion versus treatment as usual (no tube) in Greenlandic children aged 9-36 months with chronic otitis media with effusion or recurrent acute otitis media...
January 19, 2017: Trials
https://www.readbyqxmd.com/read/28101414/anti-confocal-assessment-of-middle-ear-inflammation
#16
David S Jung, John A Crowe, John P Birchall, Michael G Somekh, Chung W See
To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28056905/determinants-of-chronic-otitis-media-with-effusion-in-preschool-children-a-case-control-study
#17
Rebecca E Walker, Jim Bartley, David Flint, John M D Thompson, Edwin A Mitchell
BACKGROUND: Chronic otitis media with effusion (COME) is a prevalent upper airway infection resulting in hearing loss. The aim of this research was to determine risk factors for COME in preschool children. METHODS: A case-control design was conducted in Auckland, New Zealand from May 2011 until November 2013. The cases were children aged 3 and 4 years referred for tympanostomy tube placement due to a diagnosis of COME (n = 178). The controls were a random sample of healthy children aged 3 and 4 years from primary care practices (n = 209)...
January 6, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28027286/the-relationship-of-the-middle-ear-effusion-microbiome-to-secretory-mucin-production-in-pediatric-patients-with-chronic-otitis-media
#18
Anna Krueger, Stéphanie Val, Marcos Pérez-Losada, Karuna Panchapakesan, Joe Devaney, Vanessa Duah, Christine DeMasson, Marian Poley, Mary Rose, Diego Preciado
BACKGROUND: Acute otitis media (AOM), an infection of the middle ear, can become chronic (COM) following multiple episodes. Microbial influence on COM remains unclear. It's been reported that mucin glycoproteins are required for middle ear immune defense against pathogens. We aim to characterize the middle ear effusion (MEE) microbiome using high-throughput sequencing and assess potential associations in microbiome diversity with the presence of the secretory mucins MUC5B and MUC5AC. We hypothesize that MEEs containing MUC5B will exhibit a microbiome largely devoid of typical AOM bacteria...
December 23, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28025609/indications-for-tonsillectomy-stratified-by-the-level-of-evidence
#19
REVIEW
Jochen P Windfuhr
Background: One of the most significant clinical trials, demonstrating the efficacy of tonsillectomy (TE) for recurrent throat infection in severely affected children, was published in 1984. This systematic review was undertaken to compile various indications for TE as suggested in the literature after 1984 and to stratify the papers according to the current concept of evidence-based medicine. Material and methods: A systematic Medline research was performed using the key word of "tonsillectomy" in combination with different filters such as "systematic reviews", "meta-analysis", "English", "German", and "from 1984/01/01 to 2015/05/31"...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/27995276/seasonal-differences-of-tympanogram-and-middle-ear-findings-in-children
#20
S Knopke, A Böttcher, P Chadha, H Olze, F Bast
BACKGROUND: It is a known fact that bacterial or viral acute otitis media occurs more frequently in the winter months. Only a few older studies on seasonal differences in middle ear findings are available. These studies are based solely on tympanography, without correlation to intraoperative middle ear findings. This study addresses the question of whether seasonal differences can be found in the preoperative tympanogram and in the corresponding intraoperative findings in children with chronic middle ear problems...
December 19, 2016: HNO
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