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Otitis media effusion

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https://www.readbyqxmd.com/read/29135867/analysis-of-otologic-features-of-patients-with-primary-ciliary-dyskinesia
#1
Kazuhiko Takeuchi, Masako Kitano, Hiroshi Sakaida, Satoko Usui, Sawako Masuda, Satoru Ogawa, Makoto Ikejiri, Mizuho Nagao, Takao Fujisawa, Kaname Nakatani
OBJECTIVE: To evaluate otologic features of primary ciliary dyskinesia (PCD), especially eardrum features, audiometric findings, and clinical course. STUDY DESIGN: Retrospective patient review. SETTING: Tertiary referral center. PATIENTS: Fifteen patients (mean age, 16.9 years [range, 1-32 yr]; 8 males and 7 females) diagnosed with PCD at our university hospital in the last 12 years. INTERVENTION: Diagnostic...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29125825/understanding-the-aetiology-and-resolution-of-chronic-otitis-media-from-animal-and-human-studies
#2
REVIEW
Mahmood F Bhutta, Ruth B Thornton, Lea-Ann S Kirkham, Joseph E Kerschner, Michael T Cheeseman
Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, and Eustachian tube function...
November 1, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29106777/quality-of-questionnaires-for-the-assessment-of-otitis-media-with-effusion-in-children
#3
Richard Wei Chern Gan, Matija Daniel, Matthew Ridley, Johanna G Barry
INTRODUCTION: Audiometric tests provide information about hearing in otitis media with effusion (OME). Questionnaires can supplement this information by supporting clinical history-taking as well as potentially providing a standardized and comprehensive assessment of the impact of the disease on a child. There are many possible candidate questionnaires. This study aimed to assess the quality and usability of parent / child questionnaires in OME assessment. METHODS: Fifteen, published questionnaires, commonly used in audiological departments (ABEL, CHAPS, CHILD, COW, ECLiPS, ELF, FAPC, HL-7, LIFE-R Student, LIFE-UK IHP, LittlEARS, LSQ, OM-6, OMQ-14, PEACH) were assessed according to the following 8 criteria: conceptual clarity, respondent burden, reliability, validity, normative data, item bias, ceiling/ floor effects, and administrative burden...
November 6, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29075980/tubomanometry-value-as-an-associated-factor-for-medication-outcomes-in-adult-acute-otitis-media-with-effusion
#4
Junbo Zhang, Zhen Zhong, Shuifang Xiao, Yuhe Liu, Zhen Zhen, Lei Ren, Lei Zhang
Tubomanometry (TMM) is a relatively novel method for testing the eustachian tube (ET) function, which is speculated to be closely related to otitis media with effusion (OME). The purpose of this study is to explore the predictive power of TMM value for medication outcomes in adult acute OME. A cohort of 41 adult acute OME patients with 53 affected ears was studied retrospectively. All these patients completed a 2-week treatment including oral Myrtol Standardized Enteric capsules, nasal steroid, and oral antihistamine...
October 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29062709/encapsulated-pleural-effusion-due-to-haemophilus-influenzae-biotype-ii-in-a-child-with-trisomy-21-a-case-report-and-literature-review
#5
Masanori Kaneko, Yuki Bando, Tomohiro Fujita, Yoneji Hirose, Eisuke Suganuma, Masahiro Ishii, Takashi Takahashi
Haemophilus influenzae (Hi) can colonize in the upper respiratory tract and cause severe pulmonary infections, especially among immunocompromised children. Herein, we report a case of left encapsulated pleural effusion (EPE) due to Hi in a 24-month-old girl with trisomy 21. She was already vaccinated against Hi type b. The Hi biotype II was isolated from both the blood and aspirated sputum obtained upon admission. Ampicillin/sulbactam 180 mg/kg/day was administered intravenously for 34 days with oxygen supplementation for 4 days...
2017: IDCases
https://www.readbyqxmd.com/read/29054432/expression-pattern-of-eya4-in-the-common-marmoset-callithrix-jacchus-cochlea
#6
Saeko Matsuzaki, Makoto Hosoya, Hideyuki Okano, Masato Fujioka, Kaoru Ogawa
The eyes absent (EYA)-like genes are essential for the formation of sensory organs among fly (Drosophila melanogaster) and mammals. EYA4, one of the vertebrate genes of Eya family, is reported to be causative for late-onset mid-frequency sensorineural hearing loss in humans, while Eya4-deficient mice exhibited congenital profound deafness and otitis media with effusion due to the eustachian tube dysmorphology. Because of the species difference in the phenotype, the pathophysiology of EYA4 in the human cochlea has yet to be elucidated...
October 18, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29040145/neutrophil-lymphocyte-and-platelet-lymphocyte-ratio-for-the-effusion-viscosity-in-otitis-media
#7
Satvinder Singh Bakshi
No abstract text is available yet for this article.
October 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29039253/stakeholder-driven-quality-improvement-a-compelling-force-for-clinical-practice-guidelines
#8
Richard M Rosenfeld, Peter C Wyer
Clinical practice guideline development should be driven by rigorous methodology, but what is less clear is where quality improvement enters the process: should it be a priority-guiding force, or should it enter only after recommendations are formulated? We argue for a stakeholder-driven approach to guideline development, with an overriding goal of quality improvement based on stakeholder perceptions of needs, uncertainties, and knowledge gaps. In contrast, the widely used topic-driven approach, which often makes recommendations based only on randomized controlled trials, is driven by epidemiologic purity and evidence rigor, with quality improvement a downstream consideration...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29037099/eosinophilic-otitis-media-diagnosis-using-flow-cytometric-immunophenotyping
#9
Issam Saliba, Musaed Alzahrani, Xiaoduan Weng, Alain Bestavros
OBJECTIVES: (1) To assess the ability of flow cytometric immunophenotyping to detect and quantitate eosinophils in patients with eosinophilic otitis media (EOM). (2) to evaluate the association of EOM to bronchial asthma. METHODS: Twenty-one patients with chronic otorrhea or middle ear effusion (MEE) were included in this prospective cohort study. Group I composed of 10 patients (14 ears) and associated to bronchial asthma. Group II included 11 patients (11 ears) without bronchial asthma...
October 16, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29033123/diagnosis-and-treatment-of-otitis-media-with-effusion-codepeh-recommendations
#10
Faustino Núñez-Batalla, Carmen Jáudenes-Casaubón, Jose Miguel Sequí-Canet, Ana Vivanco-Allende, Jose Zubicaray-Ugarteche
The incidence and the prevalence rates of otitis media with effusion (OME) are high. However, there is evidence that only a minority of professionals follow the recommendations provided in clinical practice guidelines. For the purpose of improving diagnosis and treatment of OME in children to prevent and/or reduce its impact on children's development, the Commission for the Early Detection of Deafness (CODEPEH) has deeply reviewed the scientific literature on this field and has drafted a document of recommendations for a correct clinical reaction to of OME, including diagnosis and medical and surgical treatment methodology...
October 13, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28992951/the-role-of-allergy-in-otologic-disease
#11
REVIEW
Betty Yang, Christopher D Brook
Allergy is commonly associated with conditions such as rhinitis, sinusitis, and asthma, but the relationship between allergy and otologic diseases is less clear. This article examines the evidence for a relationship between allergic disease and several common otologic conditions, including otitis media with effusion, eosinophilic otitis media, and Ménière's disease.
October 6, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28970529/a-mouse-to-man-candidate-gene-study-identifies-association-of-chronic-otitis-media-with-the-loci-tgif1-and-fbxo11
#12
Mahmood F Bhutta, Jane Lambie, Lindsey Hobson, Anuj Goel, Lena Hafrén, Elisabet Einarsdottir, Petri S Mattila, Martin Farrall, Steve Brown, Martin J Burton
Chronic otitis media with effusion (COME) is the most common cause of hearing loss in children, and known to have high heritability. Mutant mouse models have identified Fbxo11, Evi1, Tgif1, and Nisch as potential risk loci. We recruited children aged 10 and under undergoing surgical treatment for COME from 35 hospitals in the UK, and their nuclear family. We performed association testing with the loci FBXO11, EVI1, TGIF1 and NISCH and sought to replicate significant results in a case-control cohort from Finland...
October 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28964306/expression-of-calcium-binding-proteins-s100a8-s100a9-and-s100a12-in-otitis-media
#13
Wenzhou Hong, Pawjai Khampang, Tina L Samuels, Joseph E Kerschner, Ke Yan, Pippa Simpson
OBJECTIVES: Calgranulins (calcium-binding proteins S100A8, S100A9 and S100A12) are predominant cytoplasmic proteins of neutrophils and produced by various cells, playing multiple functions in innate immunity and the inflammatory process. Although up-regulated expression of S100A8 and S100A9 genes were observed in an animal model of otitis media (OM), their expressions have not been studied in human middle ear epithelial cells in response to the OM pathogen or in patients with recurrent or chronic OM (recurrent OM/RecOM or chronic OM with effusion/COME)...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28964286/the-expression-and-correlation-of-hsp-70-and-hsp-27-in-serous-middle-ear-effusion-fluids-of-pediatric-patients-a-preliminary-study
#14
Hyun Jin Min, Ji Won Choe, Moon Young Chang, Kyung Soo Kim, Sei Young Lee, Seog-Kyun Mun
OBJECTIVES: Several cytokines and innate immune-associated molecules are present in middle ear effusions, but damage-associated molecular patterns (DAMPs) in middle ear effusion have not been studied. Therefore, we evaluated the role of heat shock proteins (Hsps) in the development of otitis media with effusion (OME). METHODS: Serous middle ear effusions from 22 pediatric patients who were diagnosed with OME and underwent ventilation tube insertion from June 2015 to March 2017 were evaluated in our study...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28955677/acute-lymphoblastic-leukemia-following-nasopharyngeal-carcinoma-report-of-an-unusual-case
#15
Hamid Farhangi, Mahdi Silanian Toosi, Seied Ali Alamdaran, Sepideh Bagheri
INTRODUCTION: Nasopharyngeal carcinoma (NPC) is a rare malignancy in children. Nasal obstruction, otitis media with effusion, pain in the ear, hearing problems, and unusual neck mass are among the signs and symptoms of this malignancy. CASE REPORT: We report the case of a 13-year-old girl with NPC who later developed acute lymphoblastic leukemia (ALL) through the course of her disease. To our knowledge, this is the first report of ALL following childhood nasopharyngeal carcinoma in the English-language literature...
September 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28918655/what-not-to-do-in-acute-otitis-media-the-top-five-recommendations-proposed-by-the-italian-society-of-preventive-and-social-pediatrics
#16
Elena Chiappini, Barbara Bortone, Mattia Doria, Massimo Landi, Giuseppe Di Mauro, Paola Marchisio
With the aim to reduce inappropriate procedures and antibiotic therapy in the management of acute otitis media (AOM) in children, the Italian Society of Preventive and Social Pediatrics (SIPPS) proposed a top five list of recommendations for clinical practice. Areas covered: AOM is one of the most frequent reasons for antibiotic prescription in pediatric age. The over-estimation of AOM is associated with inappropriate treatment, increased costs, adverse events and spread of antibiotic resistance. Thus, the most recent guidelines provided stringent diagnostic criteria and considered the 'watchful waiting' approach, limiting the immediate antibiotic therapy to a well-characterized subgroup of children...
October 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28894768/clinical-improvement-of-subacute-and-chronic-otitis-media-with-effusion-treated-with-hyaluronic-acid-plus-hypertonic-solution-via-nasal-lavage-a-randomized-controlled-trial
#17
Luigi Cioffi, Patrizia Gallo, Antonio D'Avino, Francesco Carlomagno, Giuseppe Aloi, Antonietta D'Onofrio, Donatella Del Gaizo, Maria Giuliano, Raffaella De Franchis, Maria L Sandomenico, Anna Pecoraro
Background. This study, a randomized controlled trial, aims to demonstrate a clinically significant improvement in subacute and chronic otitis media with effusion through the administration of hyaluronic acid associated with hypertonic solution compared with the administration of hypertonic solution alone. The setting was an outpatient clinic of 20 primary care pediatrician offices affiliated with the 3 Local Health Units (Azienda Sanitaria Locale) of Naples. Materials and Methods. The study was conducted for 6 months, from October 2014 to the end of March 2015...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28894551/montelukast-versus-inhaled-mometasone-for-treatment-of-otitis-media-with-effusion-in-children-a-randomized-controlled-trial
#18
Mohammad Bagher Rahmati, Fatemeh Safdarian, Babak Shiroui, Shahram Zare, Naser Sadeghi
BACKGROUND: Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate in this issue. OBJECTIVE: To compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28865502/-validation-of-the-otitis-media-6-questionnaire-for-european-portuguese
#19
Ana Rita Lameiras, Deodato Silva, Assunção O'Neill, Pedro Escada
INTRODUCTION: Otitis media is one of the most prevalent childhood diseases. The impact of otitis media on quality of life of Portuguese children is unknown, because of the unavailability of a tool validated in European Portuguese to assess this consequence of otitis media. The Otitis Media-6 questionnaire (Otitis Media-6) is the most frequently used tool to assess health-related quality of life in children with otitis media. This study aims to create a version in the Portuguese language and culturally adapted to Portugal of the otitis media-6 questionnaire...
May 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28829840/tone-perception-in-mandarin-speaking-school-age-children-with-otitis-media-with-effusion
#20
Ting Cai, Bradley McPherson, Caiwei Li, Feng Yang
OBJECTIVES: The present study explored tone perception ability in school age Mandarin-speaking children with otitis media with effusion (OME) in noisy listening environments. The study investigated the interaction effects of noise, tone type, age, and hearing status on monaural tone perception, and assessed the application of a hierarchical clustering algorithm for profiling hearing impairment in children with OME. METHODS: Forty-one children with normal hearing and normal middle ear status and 84 children with OME with or without hearing loss participated in this study...
2017: PloS One
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