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https://www.readbyqxmd.com/read/29765395/progressive-neurological-decline-with-deep-bilateral-imaging-changes-a-protean-presentation-of-dural-arteriovenous-fistulae
#1
Rene A Colorado, Marcelo Matiello, Hyun-Sik Yang, James D Rabinov, Aman Patel, Joshua A Hirsch, Ram Chavali, Thabele M Leslie-Mazwi
Intracranial dural arteriovenous fistulae (DAVF) within the deep cerebral vasculature are diagnostically challenging because of their variable clinical presentation and typical bilateral neuroimaging findings mimicking inflammatory, infectious, and metabolic processes. Increasingly, reports have emerged highlighting the diagnostic and treatment challenges of these lesions and their associated high morbidity and rapid clinical deterioration when untreated. We describe here a case series of 4 patients with deep cerebral DAVF who presented with impaired arousal or memory and behavioral changes...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29762436/preoperative-analysis-of-venous-anatomy-before-deep-inferior-epigastric-perforator-free-flap-breast-reconstruction-using-ferumoxytol-enhanced-magnetic-resonance-angiography
#2
John Dortch, Antonio J Forte, Candice Bolan, Pujan Kandel, Galen Perdikis
BACKGROUND: Venous congestion after deep inferior epigastric artery perforator (DIEP) flap breast reconstruction is a complication that may be partially attributable to variations in venous abdominal wall anatomy. In previous work, we have shown that ferumoxytol may be used as a bloodpool contrast agent to perform high-resolution venous imaging. Our current aim was to use this technology to perform a detailed analysis of the venous anatomy among patients undergoing DIEP flap breast reconstruction...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29732225/cortical-blindness-and-altered-mental-status-following-routine-hemodialysis-a-case-of-iatrogenic-cerebral-air-embolism
#3
Lawrence Lau, Kory London
Cerebral air embolism is a known complication from a myriad of iatrogenic causes. This case describes a 60-year-old female presenting from hemodialysis with altered mental status, bilateral homonymous hemianopia, and repetitive speech. A noncontrast head CT revealed air in the vein of Galen and the deep cerebral veins of the left thalamus and occipital sulcus, a complication from air being introduced into the patient via improper flushing of dialysis tubing. The retrograde flow of air bubbles in the upright patient during dialysis was likely responsible for the air embolus lodging in the cerebral vasculature...
2018: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/29682048/choroidal-type-of-vein-of-galen-aneurysmal-malformation-in-adult-patient-with-unusual-presentation-of-orthostatic-headache
#4
Kapil Pareek, Trilochan Shrivastava, Virendra Deo Sinha
Vein of Galen aneurysmal malformations (VGAMs) are rare vascular malformations occurring commonly in the pediatric age group. They comprise only 1% of all intracranial vascular malformations, but in pediatric population, they represent 30% of all intracranial vascular malformations. They are of two types-mural and choroidal. Choroidal type of VGAM is more primitive and most severe form of disease. It usually causes high cardiac output failure in newborn period because of multiple high flow fistulas. Adult presentation of choroidal type VGAM is very rare, and only few cases have been reported in literature so far...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29657906/imaging-characteristics-of-dural-arteriovenous-fistulas-involving-the-vein-of-galen-a-comprehensive-review
#5
REVIEW
Mohammad W Kassem, Paul J Choi, Joe Iwanaga, Martin M Mortazavi, R Shane Tubbs
Vein of Galen aneurysmal malformation (VGAM) is a rare angiopathy, which most commonly presents in infancy. Although very rare, it is associated with high morbidity and mortality rates. In order to minimize such morbid rates, a prompt diagnosis followed by a timely initiation of management is crucial. Multiple antenatal and postnatal imaging techniques for the diagnosis have been described and discussed in the literature. However, to our knowledge, a comprehensive review exploring such a list of imaging options for VGAM has never been established...
February 11, 2018: Curēus
https://www.readbyqxmd.com/read/29649643/estimating-the-global-incidence-of-aneurysmal-subarachnoid-hemorrhage-a-systematic-review-for-central-nervous-system-vascular-lesions-and-meta-analysis-of-ruptured-aneurysms
#6
REVIEW
Joshua D Hughes, Kamila M Bond, Rania A Mekary, Michael C Dewan, Abbas Rattani, Ronnie Baticulon, Yoko Kato, Hildo Azevedo-Filho, Jacques J Morcos, Kee B Park
INTRODUCTION: There is increasing acknowledgement that surgical care is important in global health initiatives. In particular, neurosurgical care is as limited as 1-to-10 million people in parts of the world. We performed a systematic literature review to examine the worldwide incidence of central nervous system vascular lesions (CNS-VL) and a meta-analysis of aneurysmal subarachnoid hemorrhage (ASAH) in order to define the disease burden and inform neurosurgical global health efforts...
April 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29596666/discovery-of-a-cause-of-vein-of-galen-malformations
#7
James F Meschia
No abstract text is available yet for this article.
April 1, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29535897/adjuvant-coil-assisted-glue-embolization-of-vein-of-galen-aneurysmal-malformation-in-pediatric-patients
#8
Dong Joon Kim, Dae Chul Suh, Byung Moon Kim, Dong Ik Kim
Purpose: Adjuvant coils may offer advantages in flow control during glue embolization of high flow vein of Galen aneurysmal malformation (VGAM) patients but involves specific issues such as feasibility, durability and coil mass effect. The purpose of this study is to assess the outcome of adjuvant coils in addition to transarterial glue embolization for treatment of these patients. Materials and Methods: Five pediatric VGAM patients (age range; 11 weeks to 2 yrs 2 mos) with high flow fistulous angioarchitecture were treated with adjuvant coils 1) in the distal feeding artery and/or 2) in the vein of Galen followed by glue embolization of the shunt...
March 2018: Neurointervention
https://www.readbyqxmd.com/read/29510637/-vein-of-galen-aneurysmal-malformation
#9
A Drobníková, Z Vocásek, M Kacerovský
OBJECTIVE: A case report of the pregnancy complicated by the presence of vein of Galen aneurysmal malformation in fetus. DESIGN: The case report. SETTING: Department of Obstetrics and Gynaecology, Masaryks Hospital, Jilemnice; Obstetrics and Gynecology Clinic, University Hospital in Hradec Králové. CASE REPORT: The description of the pregnancy complicated by the presence of vein of Galen aneurysmal malformation in a fetus 32 weeks gestation which led to a progressive heart failure and the development of the hydrocephalus...
December 0: Ceská Gynekologie
https://www.readbyqxmd.com/read/29444212/loss-of-function-mutations-in-ephb4-are-responsible-for-vein-of-galen-aneurysmal-malformation
#10
Alexandre Vivanti, Augustin Ozanne, Cynthia Grondin, Guillaume Saliou, Loic Quevarec, Helène Maurey, Patrick Aubourg, Alexandra Benachi, Marta Gut, Ivo Gut, Jelena Martinovic, Marie Victoire Sénat, Marcel Tawk, Judith Melki
See Meschia (doi:10.1093/brain/awy066) for a scientific commentary on this article.Vein of Galen aneurysmal malformation is a congenital anomaly of the cerebral vasculature representing 30% of all paediatric vascular malformations. We conducted whole exome sequencing in 19 unrelated patients presenting this malformation and subsequently screened candidate genes in a cohort of 32 additional patients using either targeted exome or Sanger sequencing. In a cohort of 51 patients, we found five affected individuals with heterozygous mutations in EPHB4 including de novo frameshift (p...
April 1, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29442365/vein-of-galen-malformation-optimizing-the-management-of-postneonatal-presentations
#11
Dan Meila
No abstract text is available yet for this article.
April 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29436506/non-enhanced-mr-imaging-for-preinterventional-assessment-of-the-angioarchitecture-in-vein-of-galen-malformations
#12
Nikola Reinhard Dürr, Waleed Brinjikji, Anne Pohrt, Henrich Lanfermann, Friedhelm Brassel, Dan Meila
BACKGROUND AND PURPOSE: Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. MATERIALS AND METHODS: We retrospectively evaluated a consecutive series of VGM patients who underwent a 1...
February 7, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29408495/multimodality-management-of-vein-of-galen-malformations-an-institutional-experience
#13
Arthur Hosmann, Ahmed El-Garci, Brigitte Gatterbauer, Gerhard Bavinzski, Engelbert Knosp, Andreas Gruber
BACKGROUND: The vein of Galen aneurysmal malformation (VGM) is a rare intracranial arteriovenous fistula with a dramatic manifestation during infancy and 100% mortality without treatment. Therapeutic strategies for VGMs have changed over time as a result of advances in endovascular techniques. We present our experience and multimodality approach within the last 4 decades. METHODS: A retrospective analysis and angiographic review were performed of patients with VGM between 1975 and 2016 at our institution...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29372854/adenosine-induced-cardiac-standstill-for-endovascular-treatment-of-pediatric-vein-of-galen-malformations
#14
Nam K Yoon, Jonathan P Scoville, Philipp Taussky
Vein of Galen malformations are congenital high-flow vascular malformations that often present with heart failure, hydrocephalus, developmental delay, and intracranial hemorrhage. Because open surgical treatment is associated with high morbidity and mortality, endovascular embolization is increasingly becoming the preferred method of intervention. However, embolization of these lesions can be difficult because of their high-flow nature. The use of adenosine-induced cardiac standstill for treatment of vein of Galen malformations has not been previously described in neonates...
April 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29359331/presentation-course-and-outcome-of-postneonatal-presentations-of-vein-of-galen-malformation-a-large-single-institution-case-series
#15
Vignesh Gopalan, Adam Rennie, Fergus Robertson, Lakshmi Kanagarajah, Claire Toolis, Sanjay Bhate, Vijeya Ganesan
AIM: To describe presentation, clinical course, and outcome in postneonatal presentations of vein of Galen malformation (VGM). METHOD: Children older than 28 days presenting with VGM (from 2006-2016) were included. Notes/scans were reviewed. Outcome was dichotomized into 'good' or 'poor' using the Recovery and Recurrence Questionnaire. Logistic regression was performed to explore relationships between clinico-radiological features and outcome. RESULTS: Thirty-one children (18 males, 13 females) were included, presenting at a median age of 9...
April 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29350590/human-genetics-and-molecular-mechanisms-of-vein-of-galen-malformation
#16
Daniel Duran, Philipp Karschnia, Jonathan R Gaillard, Jason K Karimy, Mark W Youngblood, Michael L DiLuna, Charles C Matouk, Beverly Aagaard-Kienitz, Edward R Smith, Darren B Orbach, Georges Rodesch, Alejandro Berenstein, Murat Gunel, Kristopher T Kahle
Vein of Galen malformations (VOGMs) are rare developmental cerebrovascular lesions characterized by fistulas between the choroidal circulation and the median prosencephalic vein. Although the treatment of VOGMs has greatly benefited from advances in endovascular therapy, including technical innovation in interventional neuroradiology, many patients are recalcitrant to procedural intervention or lack accessibility to specialized care centers, highlighting the need for improved screening, diagnostics, and therapeutics...
April 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29322704/evaluation-of-cerebral-venous-thrombosis-by-ct-mri-and-mr-venography
#17
Pratibha Issar, Sirasapalli Chinna, Sanjeev Kumar Issar
Objective: To study and compare cerebral parenchymal changes and sinuses involvement in CT with MRI and MRV in Cerebral Venous Thrombosis patients. Method: This study was carried out in the Department of Radiodiagnosis, JLN Hospital and Research Center, Bhilai, Chhattisgarh from October 2012 to Nov 2014 and includes fifty patients of all age groups presenting with clinical symptoms of CVT, admitted in Neurology, Neurosurgery, Medicine, Pediatric, obstetric and Gynecology wards...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29125026/delayed-and-incomplete-treatment-may-result-in-dural-fistula-development-in-children-with-vein-of-galen-malformation
#18
Dan Meila, Cynthia Schmidt, Katharina Melber, Dominik Grieb, Cornelius Jacobs, Collin Jacobs, Heinrich Lanfermann, Friedhelm Brassel
The association of dural arteriovenous fistulas (DAVF) in children with Vein of Galen malformation (VGM) has recently been reported for the first time. In a larger series of cases treated with transarterial NBCA embolization, 30% had DAVF. We wanted to analyze the development of DAVF in our cohort of children with VGM and to evaluate whether their occurrence depends on different treatment timing and embolic materials. We analyzed 43 VGM cases treated with a combined transarterial and transvenous approach between 2003 and 2016...
February 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29082570/galenic-pial-arteriovenous-fistulas-angioarchitecture-clinical-presentation-and-therapeutic-considerations
#19
REVIEW
Michael George Zaki Ghali
Vein of Galen (VG) aneurysmal malformations (VGAMs) are complex vascular lesions. Their etiopathogenesis is extensively debated and remains poorly understood. Strictly speaking, true VGAMs are Galenic pial arteriovenous fistulas. They are believed to arise in utero and are contended to drain either into the true VG or the median prosencephalic vein of Markowski. Several classification systems have been proposed and are widely used. With the advent of endovascular therapy, precise understanding of the angioarchitecture is critical for management and therapeutic decision making...
March 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/28982789/endovascular-treatment-of-vein-of-galen-malformations-a-systematic-review-and-meta-analysis
#20
W Brinjikji, T Krings, M H Murad, A Rouchaud, D Meila
BACKGROUND: Outcomes after endovascular embolization of vein of Galen malformations remain relatively poorly described. PURPOSE: We performed a systematic review of the literature to determine outcomes and predictors of good outcomes following endovascular treatment of vein of Galen malformations. DATA SOURCES: We used Ovid MEDLINE, Ovid Embase, and the Web of Science. STUDY SELECTION: Our study consisted of all case series with ≥4 patients receiving endovascular treatment of vein of Galen malformations published through January 2017...
December 2017: AJNR. American Journal of Neuroradiology
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