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Juan Gros-Otero, Montserrat Garcia-Gonzalez, Miguel A Teus, MariLuz Iglesias-Iglesias, Carlos Gimenez-Vallejo
PURPOSE: To compare femtosecond laser-assisted sub-Bowman keratomileusis (FSBK) versus laser-assisted subepithelial keratomileusis (LASEK) to correct moderate to high myopic astigmatism. METHODS: Retrospective, nonrandomized, interventional, comparative case series. A total of eight hundred and fifty-two eyes with myopic astigmatism of -1.5 diopters (D) or higher were included in the study. We compared 427 eyes treated with FSBK versus 425 eyes treated with LASEK with or without mitomycin C...
October 13, 2016: Journal of Optometry
P Puz, A Lasek-Bal, P Radecka
BACKGROUND: Transcranial sonography may be applied to assess the basal ganglia nuclei and brain atrophy by the measurement of the width of the third ventricle. The aim of this study was to assess usefulness of transcranial sonography (TCS) in patients with multiple sclerosis (MS) by examining the echogenicity of subcortical structures and the width of the third ventricle. METHOD: Transcranial sonography evaluation of substantia nigra, brain stem raphe nuclei, diameter of the third ventricle, width of the anterior horn of the lateral ventricle, thalamus, lenticular nucleus, and head of the caudate nucleus in 41 patients with relapsing-remitting MS (RRMS), 23 with secondary progressive MS (SPMS), and 20 healthy controls was compared...
September 18, 2016: Acta Neurologica Scandinavica
F Gonzales, N Ramdane, C Delebarre-Sauvage, P Modiano, A Duhamel, A Lasek
Atopic dermatitis (AD), is a chronic, inflammatory disease with a worldwide prevalence of 10 to 20% (1). Although topical corticosteroids (TCS) are known to be efficient and safe for the treatment of AD (2), there is a widespread fear about their use (topical corticosteroid phobia (TCSP)) in 40 to 73% of patients (3,4). TCSP represents the main cause of treatment failure. Until now, TCSP has been evaluated with a single binary question which is not adapted for this complex phenomenon. This article is protected by copyright...
September 8, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Przemyslaw Puz, Anetta Lasek-Bal, Tomasz Urbanek, Zofia Kazibutowska
AIM: Carotid artery stenosis can result in the brain tissue injury related to the intracranial aterial flow disturbances as well as microembolic complications. The choice of the proper therapy in patients with carotid artery stenosis, especially asymptomatic, remains still a significant clinical problem. The study aim was an assessment of the cerebral embolism and brain vascular reserve parameters in patients with carotid artery stenosis regarding the occurrence of the clinical symptoms, the degree of stenosis as well as plaque morphology...
2016: Neurologia i Neurochirurgia Polska
Amy W Lasek
The brain extracellular matrix (ECM) occupies the space between cells and is involved in cell-matrix and cell-cell adhesion. However, in addition to providing structural support to brain tissue, the ECM activates cell signaling and controls synaptic transmission. The expression and activity of brain ECM components are regulated by alcohol exposure. This review will discuss what is currently known about the effects of alcohol on the activity and expression of brain ECM components. An interpretation of how these changes might promote alcohol use disorder (AUD) will be also provided...
October 2016: Alcoholism, Clinical and Experimental Research
Anna Majewska, Witold Lasek, Michał Janyst, Grazyna Młynarczyk
Key issues in the development of novel antivirals are the emergence of resistant strains. The development of new drugs effective against herpes diseases has proven to be both difficult and time-consuming. Some alternative may be to optimize the efficacy and selectivity of existing antiviral drugs or combining them with other well known agents. Inosine pranobex exerts a direct antiviral effect as well as secondary effect to its immunomodulatory activity. We found that increasing concentrations of inosine pranobex (50-400 µg/mL) produced progressively growing inhibitory effect on HHV-1 replication, following infection of different cell lines...
May 2016: Acta Poloniae Pharmaceutica
Katarzyna Zbierska, Jakub Kenig, Anna Lasek, Mateusz Rubinkiewicz, Piotr Wałęga
UNLABELLED: Acute appendicitis (AA) still remains the most common acute surgical abdominal emergency. Although 90% of cases occur in children and young adults, the incidence in the elderly amounts up to 10% and is constantly rising. The aim of the study was to assess the differences between clinical presentation in the elderly patients with AA compared to the younger patients. Additional aim was to assess the correlation between in-hospital time delays and patients' outcomes. MATERIAL AND METHODS: We conducted a retrospective analysis of medical data of 274 patients admitted to 3rd Department of General Surgery in Cracow between January 2011 and December 2013 due to AA...
May 1, 2016: Polski Przeglad Chirurgiczny
Dan Fu, Zhen-Yong Zhang, Lin Wang, Xing-Tao Zhou, Zhi-Qiang Yu
This retrospective study aimed to explore refractive regression and central corneal thickness (CCT) following laser-assisted subepithelial keratectomy (LASEK) performed for the correction of high myopia in eyes with thin corneas. Forty patients (19 male, 21 female; mean age, 28.5 years) representing 76 treated eyes were included. The mean optical zone was 6.10 ± 0.32 mm, and the mean ablation depth was 121.53 ± 15.48 µm. CCT was significantly greater three years after surgery than at three months after surgery (425...
July 1, 2016: Seminars in Ophthalmology
R Autrata, I Krejčířová, L Griščíková, Z Doležel
UNLABELLED: Our study evaluated the visual and refractive results of LASEK and anterior chamber phakic intraocular lens (pIOL) implantation performed for high myopic anisometropia with amblyopia and contact lens intolerance in children compared with conventional treatment by contact lenses.Fourty-three patients (Group A) aged 3 to 7 years (mean, 5,6 years) with high myopic anisometropia and amblyopia had performed multizonal LASEK (27 eyes) or pIOL Verisyse implantation (16 eyes) on the more myopic eye in general anesthesia...
2016: Ceská a Slovenská Oftalmologie
Anetta Lasek-Bal, Zbigniew Gąsior
INTRODUCTION: Approximately 10-15% of patients with stroke are under 65 years of age. The aim of the study was to determine types of stroke In people below 65. We analysed the incidence and types of associated cardiovascular diseases in patients with non-cardiogenic stroke. MATERIAL AND METHODS: In this prospective study patients (aged ≤ 65) with stroke underwent physical examination, computed tomography of the head, blood tests, electrocardiogram, echocardiography, and transcranial and carotid artery ultrasound...
June 1, 2016: Archives of Medical Science: AMS
Piotr Budzyński, Michał Pędziwiatr, Jakub Kenig, Anna Lasek, Marek Winiarski, Piotr Major, Piotr Wałęga, Michał Natkaniec, Mateusz Rubinkiewicz, Joanna Rogala, Andrzej Budzyński
UNLABELLED: Bowel obstruction is a common condition in acute surgery. Among the patients, those with a history of cancer consist a particular group. Difficulties in preoperative diagnosis - whether obstruction is benign or malignant and limited treatment options in patients with reoccurrence or dissemination of the cancer are typical for this group. The aim of the study was to analyze causes of bowel obstruction in patients with history of radical treatment due to malignancy. MATERIAL AND METHODS: Patients with symptoms of bowel obstruction and history of radical treatment for malignancy who were operated in 2nd and 3rd Department of General Surgery JUCM between 2000 and 2014 were included into the study...
March 1, 2016: Polski Przeglad Chirurgiczny
Anetta Lasek-Bal, Tomasz Urbanek, Przemysław Puz, Marek Piekarski
No abstract text is available yet for this article.
2016: Kardiologia Polska
Joanna Wieczorek, Katarzyna Mizia-Stec, Anetta Lasek-Bal, Piotr Wieczorek, Andrzej Hoffmann, Seweryn Nowak, Jarosław Kolasa, Maciej Faryan, Iwona Woźniak-Skowerska, Anna Wnuk-Wojnar
BACKGROUND: The aim was to assess the occurrence, severity and risk factors for silent white matter hyperintensities (WMH) in brain magnetic resonance imaging (MRI) in patients with atrial fibrillation (AF) and to determine the potential relationship between WHM and cognitive decline. METHODS: Seventy-four patients with paroxysmal non-valvular AF were enrolled (age 59 (IQR 50-63)years, males 45/61%). All patients were on adequate warfarin treatment before inclusion and had no history of stroke or TIA...
July 15, 2016: International Journal of Cardiology
Minjie Chen, Manrong Yu, Jinhui Dai
PURPOSE: To compare the corneal biomechanical properties after small incision lenticule extraction (SMILE) group and laser-assisted subepithelial keratomileusis (LASEK) group. METHODS: The SMILE group comprised 39 patients (75 eyes) while it was 38 patients (76 eyes) in the LASEK group. Corneal hysteresis (CH) and the corneal resistance factor (CRF) parameters were determined using the Ocular Response Analyzer preoperatively and at 1 and 3 months postoperatively...
April 29, 2016: Acta Ophthalmologica
Joanna Galindo, Ali Fadlallah, Steve Robinson, Elias Chelala, Samir A Melki
PURPOSE: To evaluate risk factors leading to loss of epithelial flap integrity in laser-assisted subepithelial keratectomy (LASEK). SETTING: Boston Eye Group, Brookline, Massachusetts, USA. DESIGN: Retrospective case study. METHODS: This retrospective chart review was performed for LASEK surgeries that occurred between January 2009 and October 2013. Logistic regression was performed to determine whether epithelium preservation was correlated with age, sex, sphere, cylinder, spherical equivalent (SE), keratometry, and central corneal thickness (CCT)...
April 2016: Journal of Cataract and Refractive Surgery
Sücattin İlker Kocamış, Hasan Basri Çakmak, Sıdıka Gerçeker, Nurullah Çağıl
PURPOSE: To investigate and compare the long-term safety, efficacy, and accuracy of PRK (photorefractive keratectomy) and LASEK (laser epithelial keratomileusis) in myopic corneas having residual corneal thickness less than 400 micron meters (µm). METHODS: The medical reports of the patients who had undergone excimer laser surface ablation between 2007-2011 and had a residual corneal thickness less than 400 µm were retrospectively reviewed. RESULTS: Forty-two eyes of 42 patients with a mean age of 28...
April 14, 2016: Seminars in Ophthalmology
Michał Adamczyk, Janusz Lasek, Agnieszka Skawińska
CO2 biofixation was investigated using tubular bioreactors (15 and 1.5 l) either in the presence of green algae Chlorella vulgaris or Nannochloropsis gaditana. The cultivation was carried out in the following conditions: temperature of 25 °C, inlet-CO2 of 4 and 8 vol%, and artificial light enhancing photosynthesis. Higher biofixation were observed in 8 vol% CO2 concentration for both microalgae cultures than in 4 vol%. Characteristic process parameters such as productivity, CO2 fixation, and kinetic rate coefficient were determined and discussed...
August 2016: Applied Biochemistry and Biotechnology
Sung A Lim, Yooyeon Park, Yu Jin Cheong, Kyung Sun Na, Choun-Ki Joo
PURPOSE: High myopia is known to be a risk factor for long-term regression after laser refractive surgery. There have been few studies about the correction of moderate myopias that did not need retreatment after long-term follow-up. We evaluated 10 years of change in visual acuity and refractive power in eyes with moderate myopia after laser refractive surgery. METHODS: We included patients that had undergone laser in situ keratomileusis (LASIK) or laser-assisted subepithelial keratectomy (LASEK) to correct their myopia and that had at least 10 years of follow-up...
April 2016: Korean Journal of Ophthalmology: KJO
M-H Commin, E Schmidt, S Duvert-Lehembre, A Lasek, C Morice, J-L Estival, S Debarbieux, E Rigal, C Pauwels, J De Quatrebarbes, A Roussel, E Goujon, P-E Stoebner, F Jouen, P Joly
BACKGROUND: Anti-p200 pemphigoid is a rare autoimmune blistering disease (AIBD) of the dermoepidermal junction, characterized by autoantibodies to laminin γ1. The clinical course of anti-p200 pemphigoid in patients remains poorly investigated. OBJECTIVES: We aimed to describe the clinical and immunological features and the course of a series of patients with anti-p200 pemphigoid. METHODS: We conducted a retrospective study by immunoblotting detection of sera on 200-kDa dermal protein extracts from the register of the French reference centre for AIBD...
October 2016: British Journal of Dermatology
J Bonigen, A Phan, S Hadj-Rabia, F Boralévi, A-C Bursztejn, C Bodemer, M Ferneiny, A-L Souillet, C Chiavérini, E Bourrat, J Miquel, P Vabres, S Barbarot, D Bessis, C Eschard, J Mazereeuw-Hautier, M Piram, P Plantin, C Abasq, A Lasek-Duriez, A Maruani, A Beauchet, E Mahé
BACKGROUND: The prevalence of childhood psoriasis is estimated at between 0.4% and 0.7%. Clinical aspects of the diseases depend on age. The aim of this study was to investigate the clinical aspects of psoriasis according to age and sex. PATIENTS AND METHODS: A cross-sectional, multicentre study of children with psoriasis was performed by investigators belonging to the Research Group of the French Society of Paediatric Dermatology. The study was conducted from April 2012 to March 2013...
May 2016: Annales de Dermatologie et de Vénéréologie
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