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https://www.readbyqxmd.com/read/29672182/oral-anticoagulant-use-in-cardiovascular-disorders-a-perspective-on-present-and-potential-indications-for-rivaroxaban
#1
A John Camm, Keith A A Fox
BACKGROUND: Four nonvitamin K antagonist oral anticoagulants (NOACs) have been approved for use in various cardiovascular indications. The direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors apixaban, edoxaban, and rivaroxaban are now increasingly used in clinical practice. For some of these agents, available data from real-world studies support the efficacy and safety data in phase III clinical trials. OBJECTIVES: This review aims to summarize the current status of trials and observational studies of oral anticoagulant use over the spectrum of cardiovascular disorders (excluding venous thrombosis), provide a reference source beyond stroke prevention for atrial fibrillation (AF) and examine the potential for novel applications in the cardiovascular field...
April 19, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29671105/mapping-and-ablation-of-rvot-type-arrhythmias-comparison-between-the-conventional-and-reversed-u-curve-methods
#2
Zhuo Liang, Xuejun Ren, Tao Zhang, Zhihong Han, Jianzeng Dong, Yunlong Wang
PURPOSE: We assessed conventional and reversed U curve methods for mapping and ablation of RVOT-type VAs. METHODS: Single-center data were reviewed from consecutive cases of symptomatic VAs of RVOT-type origin that were mapped and ablated successfully using conventional method in RVOT (pulmonary artery might be included) from January 2014 to December 2015 (cohort 1, n = 75) or conventional method in RVOT and reversed U curve in PSC (for first ablation attempt) from January 2016 to March 2017 (cohort 2, n = 60)...
April 18, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29667097/an-elevated-respiratory-quotient-predicts-complications-after-cardiac-surgery-under-extracorporeal-circulation-an-observational-pilot-study
#3
J Piot, A Hébrard, M Durand, J F Payen, P Albaladejo
Following cardiac surgery, hyperlactatemia due to anaerobic metabolism is associated with an increase in both morbidity and mortality. We previously found that an elevated respiratory quotient (RQ) predicts anaerobic metabolism. In the present study we aimed to demonstrate that it is also associated with poor outcome following cardiac surgery. This single institution, prospective, observational study includes all those patients that were consecutively admitted to the intensive care unit (ICU) after cardiac surgery with cardiopulmonary bypass, that had also been monitored using pulmonary artery catheter...
April 17, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29666905/balloon-occluded-carbon-dioxide-gas-angiography-for-internal-iliac-arteriography-and-intervention
#4
Mitsuhiro Kishino, Shuichiro Nakaminato, Yoshio Kitazume, Naoyuki Miyasaka, Toshifumi Kudo, Yukihisa Saida, Ukihide Tateishi
INTRODUCTION: The usefulness of carbon dioxide (CO2 ) gas digital subtraction angiography (DSA) has been reported for patients with renal insufficiency and allergy to iodinated contrast agents. However, CO2 gas cannot replace the iodinated contrast agent in all cases owing to some disadvantages. We describe balloon-occluded CO2 DSA (B-CO2 DSA) as an improved CO2 DSA procedure for interventions in the internal iliac artery (IIA) region and compare the quality of images obtained using conventional CO2 DSA and B-CO2 DSA...
April 17, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29664428/-case-report-and-the-surgical-treatment-of-two-cases-with-pulmonary-atresia-in-which-pulmonary-arteries-is-circulated-by-coronary-arteries
#5
Kahraman Yakut, Kürşad Tokel, Birgül Varan, İlkay Erdoğan, Murat Özkan
Pulmonary atresia (PA) and ventricular septal defect (VSD) can occur in a variety of ways, from simple valve atresia to a condition in which circulation to the pulmonary bed occurs through collateral arteries separated from the aorta and there are no real pulmonary arteries, or they are present but hypoplastic. The size of the pulmonary arteries and concomitant complex cardiac lesions are important in making decisions about treatment and correctional alternatives. While complete correction surgeries in the style of a correction of tetralogy of Fallot are performed in simpler cases, many very invasive procedures are also performed and the resulting quality of life is very variable...
April 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29663449/mild-hypothermia-33%C3%A2-c-increases-the-inducibility-of-atrial-fibrillation-an-in-vivo-large-animal-model-study
#6
Martin Manninger, Alessio Alogna, David Zweiker, Birgit Zirngast, Stefan Reiter, Viktoria Herbst, Heinrich Maechler, Burkert M Pieske, Frank R Heinzel, Helmut Brussee, Heiner Post, Daniel Scherr
OBJECTIVE: Application of therapeutic mild hypothermia in patients after resuscitation, often accompanied by myocardial infarction, cardiogenic shock and systemic inflammation may impact on cardiac rhythm. We therefore tested susceptibility to atrial arrhythmias during hyperthermia (HT, 40.5°C), normothermia (NT, 38.0°C) and mild hypothermia (MH, 33.0°C). METHODS: Nine healthy, anesthetized closed-chest landrace pigs were instrumented with a quadripolar stimulation catheter in the high right atrium and a decapolar catheter in the coronary sinus...
April 16, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29663177/intravascular-ultrasound-assessment-of-the-effects-of-rotational-atherectomy-in-calcified-coronary-artery-lesions
#7
Sung Sik Kim, Myong Hwa Yamamoto, Akiko Maehara, Novalia Sidik, Kohei Koyama, Colin Berry, Keith G Oldroyd, Gary S Mintz, Margaret McEntegart
We sought to clarify intravascular ultrasound (IVUS) features of rotational atherectomy (RA) of calcified lesions. IVUS was performed post-RA and post-stent in 38 lesions and analyzed every 1 mm. Pre-intervention IVUS was performed when the IVUS catheter crossed the lesion (n = 11). Calcium Index was average calcium angle multiplied by calcium length. We compared lowest (n = 13), middle (n = 13), and highest (n = 12) Calcium Index tertiles. Reverberations (multiple reflections from calcium) with a concave-shaped lumen in the post-RA IVUS were considered to represent RA-related calcium modification...
April 16, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29662732/institutional-review-of-hemorrhagic-pelvic-emergencies-effectively-managed-with-percutaneous-arterial-embolization
#8
Muhammad Azeemuddin, Raza Sayani, Nauman Turab, Syed M Mustahsan, Mohammad Hasan, Dawar B Khan, Fatima Mubarak
OBJECTIVE: Our aim was to review the results of pelvic arterial embolization (PAE) performed in the interventional radiology suite. METHOD: The data of all patients in whom pelvic angioembolization was performed was collected from July 2011 to June 2017. Procedures were performed by an experienced interventional radiologist. The clinical and laboratory data, as well as the outcome data, were obtained from the medical records of our hospital. The following parameters were collected for each patient, including the age, gender, presenting symptoms, site of bleeding, catheters used for embolization, material used for embolization, previous computed tomography (CT) scan and/or focused assessment with sonography for trauma (FAST) ultrasound, average hemoglobin before the procedure, and patient clinical status on discharge...
February 15, 2018: Curēus
https://www.readbyqxmd.com/read/29658870/descending-thoracic-aortic-aneurysm-rupture-treated-with-thoracic-endovascular-aortic-repair-in-a-patient-with-peripheral-artery-disease
#9
Ovidiu Stiru, Roxana Carmen Geana, Platon Pavel, Marian Croitoru, Cristian Boros, Ion Iovu, Vlad Anton Iliescu
Descending thoracic aortic aneurysm rupture is a life-threatening disease associated with high rates of morbidity and mortality. Treatment in these cases is a surgical emergency. Less invasive therapies for the treatment of this pathology have been developed over time. For descending thoracic aneurysm rupture, endovascular stent grafting is less invasive, life-saving, and a unique alternative to open repair. However, this approach is subject to anatomical and logistic limitations. The purpose of the present study is to report a case of an emergency endovascular repair for a ruptured thoracic aortic aneurysm in a patient with peripheral arterial disease, and to discuss some important issues related to this approach...
March 20, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29658281/-treatment-of-metastatic-progression-following-the-synchronous-occurrence-of-cutaneous-and-ocular-primary-melanomas
#10
Eleonóra Imrédi, Vanda Plótár, Péter Szavcsur, Gitta Pánczél, Krisztina Melegh, Krisztina Schlachter, Gabriella Liszkay
The incidence rates of cutaneous melanoma in non-Hispanic whites show an increasing tendency with age. While uveal melanoma in general is a rare disease, representing only 4% of all melanomas with an incidence rate of 0.6 per 100 000, it is still the most frequent malignancy of the eye. Synchronous occurrence of ocular and cutaneous melanoma is an exceptional rarity, due to the distinct genetic background of the diseases. We report the case of a 80-year-old man who underwent total excision of a cutaneous melanoma in 2008...
April 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29655510/histopathological-validation-of-optical-coherence-tomography-findings-of-the-coronary-arteries
#11
REVIEW
Kenichi Fujii, Rika Kawakami, Seiichi Hirota
Optical coherence tomography (OCT), a catheter-based imaging modality for the visualization of coronary arteries, is widely used during percutaneous coronary intervention to improve the understanding of the anatomy of coronary artery stenosis and to elucidate the mechanisms of atherosclerosis. In this review, we provide a short description of the histopathological validations of OCT for visualizing atherosclerotic plaques and vascular healing response after drug-eluting stent (DES) implantation. Because OCT measures the intensity of light returning from within a tissue, tissue having a higher heterogeneity of optical index of refraction, such as microcalcification deposition and foam cell accumulation on the luminal surface, may exhibit stronger optical scattering that appears as a thin-cap fibroatheroma image...
April 11, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29652685/blood-patch-in-a-jehovah-s-witness-case-report-of-a-novel-arterial-to-epidural-closed-circuit-technique
#12
Kevin R Olsen, Ashley L Screws, Stephen O Vose
Jehovah's Witness patients have unique perioperative challenges involving blood products. We describe the use of a novel method to maintain a closed circuit between a Jehovah's Witness patient's arterial blood and the epidural space while performing a blood patch for postdural puncture headache. Previously described methods have utilized venous catheters to maintain a closed circuit between the body and the epidural space. This is the first report we are aware of that utilizes a closed-circuit arterial blood supply to create an epidural blood patch in a Jehovah's Witness patient...
April 15, 2018: A&A practice
https://www.readbyqxmd.com/read/29651581/single-15-min-protocol-yields-the-same-cryoablation-size-and-margin-as-the-conventional-10-8-10-min-protocol-results-of-kidney-and-liver-swine-experiment
#13
John D Werner, Aline C Tregnago, George J Netto, Constantine Frangakis, Christos S Georgiades
INTRODUCTION: The objective was to determine the ablation size of a single 15-min freeze and compare it with the conventional 10-min freeze-8-min thaw-10-min freeze protocol. Secondary objectives were to determine the ablation margin and to ascertain whether islands of viable tissue remain within the ablation zone. MATERIALS AND METHODS: Five adult swine under general anesthesia were used. After surgical abdominal exposure, two ablations were performed in liver and two in kidney...
April 12, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29649820/accuracy-of-acid-base-diagnoses-using-the-central-venous-blood-gas-in-the-medical-intensive-care-unit
#14
Sarah J Schrauben, Dan Negoianu, Cristiana Costa, Raphael M Cohen, Stanley Goldfarb, Barry D Fuchs, Jeffrey S Berns
BACKGROUND: Acid-base disturbances are frequent in critically ill patients. Arterial blood gas (ABG) is the gold standard in the diagnosis of these disturbances, but it is invasive with potential hazards. For patients with a central venous catheter, venous blood gas (VBG) sampling may be an alternative, less-invasive diagnostic tool. However, the accuracy of a central VBG-based acid-base disorder diagnosis compared to an ABG is unknown. The primary objective of this study was to assess the accuracy of a central VBG-based acid-base disorder diagnosis compared to the "gold standard" ABG in critically ill patients...
April 12, 2018: Nephron
https://www.readbyqxmd.com/read/29642755/successful-treatment-of-ventricular-arrhythmic-storm-with-percutaneous-coronary-intervention-and-catheter-ablation-in-a-patient-with-left-ventricular-assist-device
#15
Nihat Firat Sipahi, Arash Mehdiani, Diyar Saeed, Udo Boeken, Hisaki Makimoto, Artur Lichtenberg, Hannan Dalyanoglu
INTRODUCTION: Ventricular arrhythmias are common in patients with advanced heart failure, which may also persist after sufficient intensive therapy for heart failure even with a left ventricular assist device. Although most ventricular arrhythmias have no hemodynamic relevance during left ventricular assist device support, some patients suffer from right ventricular decompensation due to ventricular arrhythmias resulting in severe hemodynamic deterioration and poor clinical outcomes. METHODS: We describe herein an left ventricular assist device patient with refractory ventricular arrhythmic storm early after left ventricular assist device implantation...
April 1, 2018: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29628942/clinical-and-angiographic-outcomes-with-the-combined-local-aspiration-and-retriever-in-the-north-american-solitaire-stent-retriever-acute-stroke-nasa-registry
#16
Tim W Malisch, Osama O Zaidat, Alicia C Castonguay, Franklin A Marden, Rishi Gupta, Chung-Huan J Sun, Coleman O Martin, William E Holloway, Nils Mueller-Kronast, Joey English, Italo Linfante, Guilherme Dabus, Hormozd Bozorgchami, Andrew Xavier, Ansaar T Rai, Michael Froehler, Aamir Badruddin, Thanh N Nguyen, M Asif Taqi, Michael G Abraham, Vallabh Janardhan, Hashem Shaltoni, Robin Novakovic, Albert J Yoo, Alex Abou-Chebl, Peng Roc Chen, Gavin W Britz, Ritesh Kaushal, Ashish Nanda, Raul G Nogueira
Background: Various techniques are used to enhance the results of mechanical thrombectomy with stent-retrievers, including proximal arrest with balloon guide catheter (BGC), conventional large bore proximal catheter (CGC), or in combination with local aspiration through a large-bore catheter positioned at the clot interface (Aspiration-Retriever Technique for Stroke [ARTS]). We evaluated the impact of ARTS in the North American Solitaire Acute Stroke (NASA) registry. Summary: Data on the use of the aspiration technique were available for 285 anterior circulation patients, of which 29 underwent ARTS technique, 131 CGC, and 125 BGC...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628223/the-distal-left-radial-artery-access-for-coronary-angiography-and-intervention-a-new-era
#17
Karim M Al-Azizi, Amir S Lotfi
BACKGROUND: Patients' intra and post procedural comfort, quick recovery, as well as procedure success, are key elements for choosing the right arterial access site. Radial artery access has been of increasing interest since it was first described. Advanced treatments of coronary lesions, from primary percutaneous interventions during ST elevation myocardial infarction cases to chronic total occlusion cases, have been increasingly done through the radial access. Distal left trans radial artery (dlTRA) is a new technique first described by Kiemineij...
March 26, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29627787/tyrosine-kinase-inhibitor-induced-rapidly-progressive-vasculopathy-after-intracranial-stent-placement
#18
Ching-Jen Chen, Brian J Sorace, Aria Shakeri, Min S Park, Andrew M Southerland, Bradford B Worrall, M Yashar S Kalani
Tyrosine kinase inhibitor (TKI) therapy for chronic myeloid leukemia (CML) has been associated with progressive peripheral arterial disease and, more recently, rare cases of intracranial vascular stenosis have been reported. We report the fourth case of TKI treatment associated intracranial vasculopathy and rapid progression of intracranial vascular stenosis following intracranial stent placement. This was a 49-year-old woman who developed right-sided weakness, paresthesias, numbness, and speech difficulties 7 years following TKI treatment for CML...
April 7, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29626978/a-novel-scoring-system-for-predicting-adherent-placenta-in-women-with-placenta-previa
#19
Kenji Tanimura, Mayumi Morizane, Masashi Deguchi, Yasuhiko Ebina, Utaru Tanaka, Yoshiko Ueno, Kazuhiro Kitajima, Tetsuo Maeda, Kazuro Sugimura, Hideto Yamada
INTRODUCTION: Placenta previa (PP) is one of the most significant risk factors for adherent placenta (AP). The aim of this study was to evaluate the diagnostic efficacy of a novel scoring system for predicting AP in pregnant women with PP. METHODS: This prospective cohort study enrolled 175 women with PP. The placenta previa with adherent placenta score (PPAP score) is composed of 2 categories: (1) past history of cesarean section (CS), surgical abortion, and/or uterine surgery; and (2) ultrasonography and magnetic resonance imaging findings...
April 2018: Placenta
https://www.readbyqxmd.com/read/29625195/idiopathic-premature-ventricular-complexes-originating-from-the-distal-great-cardiac-vein-clinical-cardiac-and-electrophysiological-characteristics-and-catheter-ablation-outcome
#20
Wenkui Lv, Xianhui Zhou, Gulinuer Yiming, Ling Zhang, Qina Zhou, Yaodong Li, Qiang Xing, Jianghua Zhang, Yanmei Lu, Hongli Wang, Guiqiu Cao, Baopeng Tang
AIMS: Although catheter ablation for idiopathic ventricular arrhythmia (VA) has been generally well-established, VA originating from the great cardiac vein (GCV) may be clinically challenging due to its epicardial origin, proximity to coronary arteries and limited accessibility. The purpose of this study was to explore its electrophysiological characteristics and identify effective mapping/ablation strategies for idiopathic premature ventricular complexes (PVCs) originating from the GCV...
April 3, 2018: Life Sciences
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