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https://www.readbyqxmd.com/read/28928586/coiling-of-central-venous-catheter-a-rare-and-preventable-complication
#1
Nitin Hayaran, Nitin Goyal, Sudipta Joy, Aruna Jain
Central venous catheter (CVC) placement is not only restricted to Intensive Care Units and operation theaters but its horizon has also expanded to the bedside placements. Meticulous care and aids such as ultrasound and fluoroscopy dramatically increase the successful placement of needles, guidewires, and catheters, but still a large number of catheter misplacements can occur. The formation of a loop in CVC is a rare complication occurring mostly during right-sided catheterization. We report a rare complication of coiling of left subclavian CVC...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28915484/spontaneous-vesicle-formation-and-vesicle-to-micelle-transition-of-sodium-2-ketooctanate-in-water
#2
Huifang Xu, Na Du, Yawen Song, Shue Song, Wanguo Hou
Single-tailed short-chain alkyl keto-acids/salts, a class of fatty acid/salt derivatives, such as sodium 2-ketooctanate (KOCOONa), are a kind of weakly acid/salt type amphiphiles and plausible prebiotic molecules, and the current understanding of their aggregation behavior in aqueous solutions is still limited. Herein, the aggregation behavior of KOCOONa in aqueous solution was studied by changing its concentration (C), using equilibrium surface tension, conductivity, and fluorescence measurements. The aggregates formed were characterized using freeze-fracture and cryogenic transmission electron microscopy, dynamic light scattering, atomic force microscopy, and confocal laser scanning microscopy...
September 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28910354/differential-impact-of-the-dual-ccr2-ccr5-inhibitor-cenicriviroc-on-migration-of-monocyte-and-lymphocyte-subsets-in-acute-liver-injury
#3
Tobias Puengel, Oliver Krenkel, Marlene Kohlhepp, Eric Lefebvre, Tom Luedde, Christian Trautwein, Frank Tacke
A hallmark of acute hepatic injury is the recruitment of neutrophils, monocytes and lymphocytes, including natural killer (NK) or T cells, towards areas of inflammation. The recruitment of leukocytes from their reservoirs bone marrow or spleen into the liver is directed by chemokines such as CCL2 (for monocytes) and CCL5 (for lymphocytes). We herein elucidated the impact of chemokine receptor inhibition by the dual CCR2 and CCR5 inhibitor cenicriviroc (CVC) on the composition of myeloid and lymphoid immune cell populations in acute liver injury...
2017: PloS One
https://www.readbyqxmd.com/read/28904468/gyriform-infarction-in-cerebral-air-embolism-imaging-mimicker-of-status-epilepticus
#4
Konark Malhotra, Appaji Rayi
Cerebral air embolism (CAE) is a potentially fatal iatrogenic complication related to common procedures including central venous catheter (CVC) removal. We report an interesting case of CAE related to CVC removal that was further complicated with status epilepticus. Neuroimaging of CAE and status epilepticus could pose diagnostic dilemmas and require consideration of wide diagnostic differentials. We discuss the clinical presentation, mechanism, and diagnostic approach, especially neuroimaging to differentiate various etiologies in CAE patients...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28902944/fixation-of-the-short-term-central-venous-catheter-a-comparison-of-two-techniques
#5
Mário Lúcio Marques Leal, Ana Beatriz Alkmim Teixeira Loyola, Alexandre Ciappina Hueb, José Dias da Silva, Marcos Mesquita, Luiz Francisley de Paiva, Mauricio Landulfo Jorge Guerrieri, João Paulo Nunes Fernandes, Artur Costa Barros, Lydia Masako Ferreira
Purpose: To compare the fixation of the central venous catheter (CVC) using two suture techniques. Methods: A clinical, analytical, interventional, longitudinal, prospective, controlled, single-blind and randomized study in adult, intensive care unit (ICU) patients. After admission and indication of CVC use, the patients were allocated to the Wing group (n = 35, catheter fixation with clamping wings and retainers) or Shoelace group (n = 35, catheter fixation using shoelace cross-tied sutures around the device)...
August 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28886075/incorporating-abundance-information-and-guiding-variable-selection-for-climate-based-ensemble-forecasting-of-species-distributional-shifts
#6
Evan P Tanner, Monica Papeş, R Dwayne Elmore, Samuel D Fuhlendorf, Craig A Davis
Ecological niche models (ENMs) have increasingly been used to estimate the potential effects of climate change on species' distributions worldwide. Recently, predictions of species abundance have also been obtained with such models, though knowledge about the climatic variables affecting species abundance is often lacking. To address this, we used a well-studied guild (temperate North American quail) and the Maxent modeling algorithm to compare model performance of three variable selection approaches: correlation/variable contribution (CVC), biological (i...
2017: PloS One
https://www.readbyqxmd.com/read/28883293/usefulness-of-a-peripherally-inserted-central-catheter-for-total-parenteral-nutrition-in-patients-with-inflammatory-bowel-disease
#7
Hirofumi Chiba, Katsuya Endo, Yasuhiro Izumiyama, Takeru Nakano, Daisuke Okamoto, Ryo Ichikawa, Hiroshi Nagai, Shin Matsumoto, Naonobu Yokoyama, Katsutoshi Yamamoto, Yusuke Shimoyama, Takeo Naito, Motoyuki Onodera, Jun Kusaka, Keiichiro Hiramoto, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Yoichi Kakuta, Yoshitaka Kinouchi, Tooru Shimosegawa
BACKGROUNDS AND AIMS: Peripherally inserted central catheters (PICC) have been widely used as a blood access route for total parenteral nutrition (TPN) in recent years. However, there have been few reports that evaluated the usefulness of PICC for patients with inflammatory bowel disease (IBD). In this study, we compared the clinical courses in patients with IBD who received TPN during their hospitalization by conventional central venous catheters (CVC) and PICC. PATIENTS AND METHODS: A total of 137 IBD patients were enrolled...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28877671/surveillance-of-device-associated-infections-and-mortality-in-a-major-intensive-care-unit-in-the-republic-of-cyprus
#8
Stelios Iordanou, Nicos Middleton, Elizabeth Papathanassoglou, Vasilios Raftopoulos
BACKGROUND: Device-associated health care-associated infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit. The aim of this study was to assess the incidence of DA-HAIs, mortality and crude excess mortality at a General Hospital's Intensive Care Unit (ICU) in the Republic of Cyprus for 1 year period. METHODS: A prospective cohort, active DA-HAIs surveillance study with the use of Health Acquired Infections (HAIs) ICU Protocol (v1...
September 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28868995/central-line-associated-bloodstream-infections-in-australian-icus-evaluating-modifiable-and-non-modifiable-risks-in-victorian-healthcare-facilities
#9
T Spelman, D V Pilcher, A C Cheng, A L Bull, M J Richards, L J Worth
Central line-associated bloodstream infections (CLABSIs) in intensive care units (ICUs) result in poor clinical outcomes and increased costs. Although frequently regarded as preventable, infection risk may be influenced by non-modifiable factors. The objectives of this study were to evaluate organisational factors associated with CLABSI in Victorian ICUs to determine the nature and relative contribution of modifiable and non-modifiable risk factors. Data captured by the Australian and New Zealand Intensive Care Society regarding ICU-admitted patients and resources were linked to CLABSI surveillance data collated by the Victorian Healthcare Associated Infection Surveillance System between 1 January 2010 and 31 December 2013...
September 4, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28859034/six-weeks-versus-3-months-of-anticoagulant-treatment-for-pediatric-central-venous-catheter-related-venous-thromboembolism
#10
Rowenne Smith, Sophie Jones, Fiona Newall
OBJECTIVE: Central venous catheters (CVCs) are the single most important predisposing factor for the development of pediatric venous thromboembolism (VTE). Treatment recommendations suggest anticoagulation for the duration of 6 weeks to 3 months. This project investigated clinical outcomes associated with 6 weeks compared with 3 months of enoxaparin therapy following diagnosis of a CVC-related VTE. METHODS: This retrospective cohort study enrolled patients aged 18 years and below treated with enoxaparin with/without unfractionated heparin for a radiologically confirmed CVC-related VTE...
August 30, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28844205/ultrasound-guided-central-venous-catheter-placement-a-structured-review-and-recommendations-for-clinical-practice
#11
REVIEW
Bernd Saugel, Thomas W L Scheeren, Jean-Louis Teboul
The use of ultrasound (US) has been proposed to reduce the number of complications and to increase the safety and quality of central venous catheter (CVC) placement. In this review, we describe the rationale for the use of US during CVC placement, the basic principles of this technique, and the current evidence and existing guidelines for its use. In addition, we recommend a structured approach for US-guided central venous access for clinical practice. Static and real-time US can be used to visualize the anatomy and patency of the target vein in a short-axis and a long-axis view...
August 28, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28839334/central-venous-catheter-related-thrombosis-in-intensive-care-patients-incidence-and-risk-factors-a-prospective-observational-study
#12
Ondrej Hrdy, Eva Strazevska, Petr Suk, Robert Vach, Radim Karlik, Jiri Jarkovsky, Igor Sas, Roman Gal
BACKGROUND: One of the complications associated with central venous catheter (CVC) placement is catheter related deep vein thrombosis (CR-DVT). However a literature search revealed little evidence of this recognised complication. The primary aim of this study was to establish the incidence rate and risk factors for the development of CR-DVT in our critically ill adult patients. METHODS: All critically ill adult patients admitted to the medical-surgical ICU with CVC inserted were included in this observational prospective study...
August 24, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/28833331/a-randomized-placebo-controlled-trial-of-cenicriviroc-for-treatment-of-nonalcoholic-steatohepatitis-with-fibrosis
#13
Scott L Friedman, Vlad Ratziu, Stephen A Harrison, Manal F Abdelmalek, Guruprasad P Aithal, Juan Caballeria, Sven Francque, Geoffrey Farrell, Kris V Kowdley, Antonio Craxi, Krzysztof Simon, Laurent Fischer, Liza Melchor-Khan, Jeffrey Vest, Brian L Wiens, Pamela Vig, Star Seyedkazemi, Zachary Goodman, Vincent Wai-Sun Wong, Rohit Loomba, Frank Tacke, Arun Sanyal, Eric Lefebvre
The aim of this study was to evaluate cenicriviroc (CVC), a dual antagonist of C-C chemokine receptor types 2 and 5, for treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. A randomized, double-blind, multinational phase 2b study enrolled subjects with NASH, a nonalcoholic fatty liver disease activity score [NAS] ≥4, and liver fibrosis (stages 1-3, NASH Clinical Research Network) at 81 clinical sites. Subjects (N = 289) were randomly assigned CVC 150 mg or placebo. Primary outcome was ≥2-point improvement in NAS and no worsening of fibrosis at year 1...
August 17, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28833129/volume-loading-augments-cutaneous-vasodilatation-and-cardiac-output-of-heat-stressed-older-adults
#14
Daniel Gagnon, Steven A Romero, Hai Ngo, Satyam Sarma, William K Cornwell, Paula Y S Poh, Douglas Stoller, Benjamin D Levine, Craig G Crandall
Primary ageing markedly attenuates cutaneous vasodilatation and the increase in cardiac output during passive heating. However, it remains unclear if these responses are maximally restrained by age-related changes in cutaneous microvascular and cardiac functions. We hypothesized that rapid volume loading performed during heat stress would increase cardiac output in older adults without parallel increases in cutaneous vasodilatation. Twelve young (Y: 26 ± 5 yrs) and ten older (O: 69 ± 3 yrs) healthy adults were passively heated until core temperature increased by 1...
August 21, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28819481/misplaced-subclavian-central-venous-catheter
#15
Negussie Alula Bekele, Worknehe Agegnehu Abebe, Jemal Zeberga Shifa
Percutaneous Central Venous Catheter (CVC) insertion using internal jugular and Subclavian veins routes is common procedure for all intensive care admitted patients and some patients in the ward as demand arises in central and referral hospitals of Botswana. This is a case report of a patient on whom a third attempt of re-inserting a CVC for fluid and total parenteral nutrition (TPN) was made. X-ray showed that left Subclavian inserted catheter was mis-directed to internal jugular vein of the same side creating discomfort to the patient...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28811093/risk-factors-for-infective-endocarditis-in-children-with-congenital-heart-diseases-a-nationwide-population-based-case-control-study
#16
Li-Chuan Sun, Chih-Cheng Lai, Cheng-Yi Wang, Ya-Hui Wang, Jen-Yu Wang, Yo-Ling Hsu, Yin-Lan Hu, En-Ting Wu, Ming-Tai Lin, Leticia B Sy, Likwang Chen
BACKGROUND: Infective endocarditis (IE) is uncommon in childhood. Its associated epidemiological characteristics in patients with congenital heart disease (CHD) remain unclear. METHODS: The study population included children born in Taiwan during the years 1997 to 2005 who were diagnosed as having CHD before 3years of age. All children were followed up until the end year of 2010, the diagnosis of infective endocarditis, or death. The demographic characteristics of patients with and without IE, the invasive procedures performed during 6months before the index date, the prophylactic antibiotics related to dental procedures, and in-hospital mortality were collected...
August 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28807074/a-model-to-predict-central-line-associated-bloodstream-infection-among-patients-with-peripherally-inserted-central-catheters-the-mpc-score
#17
Erica Herc, Payal Patel, Laraine L Washer, Anna Conlon, Scott A Flanders, Vineet Chopra
BACKGROUND Peripherally inserted central catheters (PICCs) are associated with central-line-associated bloodstream infections (CLABSIs). However, no tools to predict risk of PICC-CLABSI have been developed. OBJECTIVE To operationalize or prioritize CLABSI risk factors when making decisions regarding the use of PICCs using a risk model to estimate an individual's risk of PICC-CLABSI prior to device placement. METHODS Using data from the Michigan Hospital Medicine Safety consortium, patients that experienced PICC-CLABSI between January 2013 and October 2016 were identified...
August 15, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28801985/between-day-reliability-of-local-thermal-hyperaemia-in-the-forearm-and-index-finger-using-single-point-laser-doppler-flowmetry
#18
Gregory W McGarr, Gary J Hodges, Stephen S Cheung
OBJECTIVE: To assess between-day reliability for local thermal hyperaemia (LTH) in glabrous and non-glabrous index finger skin and non-glabrous forearm skin, with single point laser-Doppler flowmetry. METHODS: Part-1: In healthy, habitually active males (n=10), LTH was examined twice (~7-10 d apart) for both skin types on the index finger. Part-2: Identical testing was performed on the volar forearm. Local heating (33-42°C at 1°C·20 s(-1) +20 min at 44°C) was performed at all skin sites and baseline, initial peak, and plateau phases were identified...
August 12, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/28796444/the-michigan-risk-score-to-predict-peripherally-inserted-central-catheter-associated-thrombosis
#19
Vineet Chopra, Scott Kaatz, Anna Conlon, David Paje, Paul J Grant, Mary A M Rogers, Steven J Bernstein, Sanjay Saint, Scott A Flanders
BACKGROUND: Peripherally inserted central catheters (PICCs) are associated with upper extremity deep vein thrombosis (DVT). We developed a score to predict risk of PICC-related thrombosis. METHODS: Using data from the Michigan Hospital Medicine Safety consortium, image-confirmed upper-extremity DVT cases were identified. A logistic, mixed effects model with hospital-specific random intercepts was used to identify factors associated with PICC-DVT. Points were assigned to each predictor, stratifying patients into four classes of risk...
August 10, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28793993/taurolidine-citrate-heparin-lock-reduces-catheter-related-bloodstream-infections-in-intestinal-failure-patients-dependent-on-home-parenteral-support-a-randomized-placebo-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Siri Tribler, Christopher F Brandt, Anne H Petersen, Jørgen H Petersen, Kristian A Fuglsang, Michael Staun, Per Broebech, Claus E Moser, Palle B Jeppesen
Background: In patients with intestinal failure who are receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.Objective: This study investigates the efficacy and safety of the antimicrobial catheter lock solution, taurolidine-citrate-heparin, compared with heparin 100 IE/mL on CRBSI occurrence.Design: Forty-one high-risk patients receiving HPS followed in a tertiary HPS unit were randomly assigned in a double-blinded, placebo-controlled trial...
September 2017: American Journal of Clinical Nutrition
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