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Surgical ventricular restoration

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https://www.readbyqxmd.com/read/28329206/precise-moulded-autologous-pericardial-configurations-for-aortic-cusp-reconstruction
#1
Mohammad Bashar Izzat, Khaled Hamzeh, Farouk Almohammad
OBJECTIVES: In order to facilitate surgical repair of complex aortic cusp deformities and restoration of aortic valve competence, new moulds were developed to shape the glutaraldehyde-treated autologous pericardium into precise cusp-like configurations that can be used in aortic cusp reconstruction. METHODS: The new moulds embodied the natural geometry of single aortic cusps, and a series of moulds were made available to correspond with all potential aortic cusp sizes...
February 27, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28329110/mid-term-outcomes-of-concomitant-surgical-ablation-of-atrial-fibrillation-in-patients-undergoing-cardiac-surgery-for-hypertrophic-cardiomyopathy%C3%A2
#2
Elisabetta Lapenna, Alberto Pozzoli, Michele De Bonis, Giovanni La Canna, Teodora Nisi, Simona Nascimbene, Luca Vicentini, Stefania Di Sanzo, Benedetto Del Forno, Davide Schiavi, Ottavio Alfieri
OBJECTIVES: Atrial fibrillation (AF) is common in patients with hypertrophic cardiomyopathy (HCM) and it is often poorly tolerated because of loss of atrial contraction and reduced filling time with rapid ventricular rates. Restoring sinus rhythm is of great clinical benefit to HCM patients. Very few data exist regarding surgical ablation of concomitant AF in this setting. The aim of this study was to evaluate the mid-term outcome of surgical AF ablation in patients who underwent cardiac surgery due to HCM...
February 17, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28327144/computational-medical-imaging-and-hemodynamics-framework-for-functional-analysis-and-assessment-of-cardiovascular-structures
#3
REVIEW
Kelvin K L Wong, Defeng Wang, Jacky K L Ko, Jagannath Mazumdar, Thu-Thao Le, Dhanjoo Ghista
Cardiac dysfunction constitutes common cardiovascular health issues in the society, and has been an investigation topic of strong focus by researchers in the medical imaging community. Diagnostic modalities based on echocardiography, magnetic resonance imaging, chest radiography and computed tomography are common techniques that provide cardiovascular structural information to diagnose heart defects. However, functional information of cardiovascular flow, which can in fact be used to support the diagnosis of many cardiovascular diseases with a myriad of hemodynamics performance indicators, remains unexplored to its full potential...
March 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28248409/immediate-and-long-term-outcomes-of-percutaneous-transcatheter-pulmonary-valve-implantation
#4
Roland Fiszer, Paweł Dryżek, Małgorzata Szkutnik, Sebastian Góreczny, Alexandra Krawczuk, Jadwiga Moll, Tomasz Moszura, Szymon Pawlak, Jacek Białkowski
BACKGROUND: Transcutaneous pulmonary valve replacement (TPVR) has become an alternative to heart surgery for patients after previous right ventricular outflow tract (RVOT) or pulmonary artery (PA) surgical interventions. The objective was to present immediate and long-term outcomes of transcutaneous pulmonary valve replacement. METHODS: Between 06/2009 and 06/2016, 46 patients underwent TPVR. Initial diagnoses included tetralogy of Fallot, common arterial trunk, transposition of great arteries post Rastelli correction, left ventricle outflow obstruction after Ross operation, pulmonary atresia, and isolated dysplastic pulmonary valve stenosis...
March 1, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28242257/exendin-4-inhibits-structural-remodeling-and-improves-ca-2-homeostasis-in-rats-with-heart-failure-via-the-glp-1-receptor-through-the-enos-cgmp-pkg-pathway
#5
Jingjing Chen, Dandan Wang, Fangai Wang, Shaobo Shi, Yuting Chen, Bo Yang, Yanhong Tang, Congxin Huang
The glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 is a long-acting analog of GLP-1, which stimulates insulin secretion and is clinically used in the treatment of type 2 diabetes. Previous studies have demonstrated that GLP-1 agonists and analogs serve as cardioprotective factors in various conditions. Disturbances in calcium cycling are characteristic of heart failure (HF); therefore, the aim of this study was to investigate the effect of exendin-4 (a GLP-1 mimetic) on the regulation of calcium handling and to identify the underlying mechanisms in an HF rat model after myocardial infarction (MI)...
February 24, 2017: Peptides
https://www.readbyqxmd.com/read/28161770/posterior-ventricular-restoration-treatment-for-heart-failure-a-review-past-present-and-future-aspects
#6
REVIEW
Tadashi Isomura, Yasuhisa Fukada, Takuya Miyazaki, Minoru Yoshida, Akimasa Morisaki, Masahiro Endo
Congestive heart failure (CHF) is one of the major causes of death and occurs in more than 15,000,000 patients worldwide. The incidence is expected to increase in parallel with the aging population. Most current therapies for CHF are medications, and biventricular pacing implantation as appropriated by cardiologists, or surgical interventions. The heart transplantation for indicated patients is still gold standard surgery although the 10-year survival rate is approximately 60% based on the worldwide data. However, the cardiac transplantation remains epidemiologically insignificant because of donor pool limitations...
March 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28123985/catheter-directed-interventions-for-pulmonary-embolism
#7
REVIEW
Mehrzad Zarghouni, Hearns W Charles, Thomas S Maldonado, Amy R Deipolyi
Pulmonary embolism (PE), a potentially life-threatening entity, can be treated medically, surgically, and percutaneously. In patients with right ventricular dysfunction (RVD), anticoagulation alone may be insufficient to restore cardiac function. Because of the morbidity and mortality associated with surgical embolectomy, clinical interest in catheter-directed interventions (CDI) has resurged. We describe specific catheter-directed techniques and the evidence supporting percutaneous treatments.
December 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28120058/endoscopic-reconstruction-of-csf-pathways-in-ventricular-tumors
#8
Piero Andrea Oppido
Neuroendoscopy is now considered to be a minimally invasive surgical approach for expanding lesions bulging into the ventricle, and it is also considered to be a relevant tool for performing biopsy procedures, fenestration of cystic walls, or for performing tumor removal in selected cases. Furthermore, the use of neuroimaging and the accurate follow-up of brain tumor patients have allowed the documentation of tumoral and pseudotumoral cystic areas that cause the obstruction of cerebrospinal fluid (CSF) pathways...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28073576/preoperative-right-ventricular-dysfunction-should-not-preclude-surgical-ventricular-restoration
#9
EDITORIAL
Constantine L Athanasuleas
No abstract text is available yet for this article.
December 1, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28054895/concomitant-cabg-left-ventricular-restoration-and-mitral-valve-repair-for-ischemic-heart-disease
#10
Yin Zhaohua, Feng Wei, Xu Fei, Zhang Jiqiang, Du Junzhe, Song Yangwu
AIM: To evaluate the effects of combined coronary artery bypass grafting (CABG), surgical left ventricular restoration (LVR), and mitral valve repair (MVP) in treating ischemic heart disease combined with mitral regurgitation; and to evaluate the different strategies of LVR and MVP. METHODS: From January 2001 to December 2015, 61 consecutive patients with left ventricular aneurysm and ischemic mitral regurgitation underwent concomitant CABG, LVR and MVP. We evaluated the clinical and echocardiographic outcomes of the patients...
December 6, 2016: Heart Surgery Forum
https://www.readbyqxmd.com/read/28040767/endocardial-linear-infarct-exclusion-technique-for-infarcted-lateral-wall
#11
Hitoshi Yaku, Suguru Ohira, Sachiko Yamazaki, Kiyoshi Doi, Hidetake Kawajiri, Kazuki Morimoto, Satoshi Numata
We report a novel method of surgical ventricular restoration for an infarcted lateral wall: the endocardial linear infarct exclusion technique. First, transmural ventriculotomy is performed at the centre of the scar longitudinally along the coronary artery. Second, the inner layer is sutured in a longitudinal direction with 4-0 polypropylene continuous sutures to approximate the border between the normal and infarcted myocardium. Finally, the outer layer is closed with a combination of interrupted buttress and continuous over-and-over sutures with outer felt reinforcement...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27817007/contrast-enhanced-shunt-series-shuntography-compare-favorably-to-other-shunt-imaging-modalities-in-detecting-shunt-occlusion
#12
Kajetan L von Eckardstein, Kai Kallenberg, Marios-Nikos Psychogios, Bawarjan Schatlo, Veit Rohde, Hans Christoph Ludwig, Hans Christoph Bock
BACKGROUND: Obstruction is a common cause of ventriculo-peritoneal shunt failure. Head computed tomography and plain x-ray examinations of shunt tubing ("shunt series") are routinely used in patients readmitted for reemerging symptoms but are of limited value. The validity of shunt series can be improved by applying contrast agent into the system (contrast-enhanced shunt series, a.k.a. a "shuntogram" or "shuntography"). We hypothesized that contrast-enhanced shunt series have a high predictive value for shunt revision surgeries...
January 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27751580/right-ventricular-dysfunction-affects-survival-after-surgical-left-ventricular-restoration
#13
Lotte E Couperus, Victoria Delgado, Meindert Palmen, Marieke E van Vessem, Jerry Braun, Marta Fiocco, Laurens F Tops, Harriëtte F Verwey, Robert J M Klautz, Martin J Schalij, Saskia L M A Beeres
OBJECTIVE: Several clinical and left ventricular parameters have been associated with prognosis after surgical left ventricular restoration in patients with ischemic heart failure. The aim of this study was to determine the prognostic value of right ventricular function. METHODS: A total of 139 patients with ischemic heart failure (62 ± 10 years; 79% were male; left ventricular ejection fraction 27% ± 7%) underwent surgical left ventricular restoration. Biventricular function was assessed with echocardiography before surgery...
September 23, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27470639/alternative-splicing-of-titin-restores-diastolic-function-in-an-hfpef-like-genetic-murine-model-ttn%C3%AE-iajxn
#14
Mathew Bull, Mei Methawasin, Joshua Strom, Pooja Nair, Kirk Hutchinson, Henk Granzier
RATIONALE: Patients with heart failure with preserved ejection fraction (HFpEF) experience elevated filling pressures and reduced ventricular compliance. The splicing factor RNA-binding motif 20 (RBM20) regulates the contour length of titin's spring region and thereby determines the passive stiffness of cardiomyocytes. Inhibition of RBM20 leads to super compliant titin isoforms (N2BAsc) that reduce passive stiffness. OBJECTIVE: To determine the therapeutic potential of upregulating compliant titin isoforms in an HFpEF-like state in the mouse...
September 2, 2016: Circulation Research
https://www.readbyqxmd.com/read/27436878/transapical-beating-heart-mitral-valve-repair-with-an-expanded-polytetrafluoroethylene-cordal-implantation-device-initial-clinical-experience
#15
MULTICENTER STUDY
James S Gammie, Peter Wilson, Krzysztof Bartus, Andrzej Gackowski, Judy Hung, Michael N D'Ambra, Piotr Kolsut, Gregory J Bittle, Piotr Szymanski, Jerzy Sadowski, Boguslaw Kapelak, Agata Bilewska, Mariusz Kusmierczyk, Mehrdad Ghoreishi
BACKGROUND: Degenerative mitral valve (MV) disease is a common cause of severe mitral regurgitation (MR) and accounts for the majority of MV operations. Conventional MV surgery requires cardiopulmonary bypass, aortic cross-clamping, cardioplegia, and a thoracotomy or sternotomy and, therefore, is associated with significant disability, risks, and unpredictable rates of MV repair. Transesophageal echocardiography-guided beating-heart MV repair with expanded polytetrafluoroethylene cordal insertion has the potential to significantly reduce surgical morbidity...
July 19, 2016: Circulation
https://www.readbyqxmd.com/read/27434273/hemodynamic-assessment-of-a-murine-heterotopic-biventricularly-loaded-cardiac-transplant-in-vivo-model
#16
Agnieszka A Książek, Katharyn J Mitchell, Laurent Morax, Colin C Schwarzwald, Simon P Hoerstrup, Benedikt Weber
BACKGROUND: Heterotopic heart transplantation (HHT) in rodent animal models represents an important technique enabling studies on organ transplantation immunology and pharmaceutical development. Recent investigations used nonworking HHT designs, with the left ventricle (LV) bypassed in the anastomosis system. In spite of their principal success, the lack of orthogonal ventricular filling leads to myocardial atrophy. However, when focusing on the cellular and molecular mechanisms involved in the in vivo remodeling of the myocardium or cell-based cardiovascular implants, a nonworking model is suboptimal as it lacks the native-analogous hemodynamic and metabolic situation...
2016: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/27344282/primary-cardiac-tumors-in-infants-and-children-surgical-strategy-and-long-term-outcome
#17
Eva Maria Delmo Walter, Mariano Francisco Javier, Frank Sander, Bernd Hartmann, Axel Ekkernkamp, Roland Hetzer
BACKGROUND: Primary cardiac tumors in infants and children are extremely rare; hence, there is very little literature available, and most knowledge is based on collections of case reports. This report is a comprehensive review of our 26-year experience with primary cardiac tumors in children with emphasis on surgical indications, strategies, and long-term outcome. METHODS: Between 1986 and 2012, 47 children (mean age 5.9 ± 2.4 months; range, 1 day to 17 years) underwent either subtotal or total resection of cardiac tumors (rhabdomyoma, 13; fibroma, 12; teratoma, 9; myxoma, 8; hemangioma, 2; rhabdomyosarcoma, 1; non-Hodgkin's lymphoma, 1; lymphangioma, 1)...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27335197/-corrected-transposition-of-the-great-arteries
#18
REVIEW
Carlos Alva-Espinosa
Corrected transposition of the great arteries is one of the most fascinating entities in congenital heart disease. The apparent corrected condition is only temporal. Over time, most patients develop systemic heart failure, even in the absence of associated lesions. With current imaging studies, precise visualization is achieved in each case though the treatment strategy remains unresolved. In asymptomatic patients or cases without associated lesions, focalized follow-up to assess systemic ventricular function and the degree of tricuspid valve regurgitation is important...
May 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27329296/approach-to-residual-pulmonary-valve-dysfunction-in-adults-with-repaired-tetralogy-of-fallot
#19
REVIEW
Yuli Y Kim, Emily Ruckdeschel
Residual right ventricular outflow tract and pulmonary valve disease is common in adults with repaired tetralogy of Fallot. Chronic severe pulmonary regurgitation as a result of surgical repair can lead to myriad complications including right ventricular dysfunction, decreased exercise tolerance, right heart failure and symptomatic arrhythmias. The aim of restoring pulmonary valve integrity is to preserve right ventricular size and function with the intent of mitigating the development of symptoms and poor long-term outcomes...
October 1, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27222185/-surgical-ventricular-restoration-versus-isolated-coronary-artery-bypass-grafting-for-left-ventricular-aneurysm-comparison-of-mid-to-long-term-outcomes
#20
COMPARATIVE STUDY
Lei-Lei Shen, Cheng Wang, Rong Wang, Cang-Song Xiao, Yang Wu, Yao Wang, Zhi-Yun Gong, Peng-Fei Guo, Hai-Zhi Zhao, Chang-Qing Gao
OBJECTIVE: To compare the mid- to long-term outcomes of patients receiving isolated coronary artery bypass grafting (CABG) versus surgical ventricular restoration (SVR) plus CABG for left ventricular aneurysms. METHODS: The clinical data were retrospectively analyzed in 205 patients with left ventricular aneurysms admitted to our hospital between January, 1997 and December, 2012, including 115 patients receiving SVR plus CABG and 90 undergoing isolated CABG. By matching preoperative echocardiographic parameters including aneurysm size, left ventricular ejection fraction (LVEF), left ventricular end-systolic volume index (LVESVI) and EuroSCORE risk factors, 32 patients receiving SVR plus CABG and another 32 with isolated CABG were enrolled in this study...
May 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
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