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https://www.readbyqxmd.com/read/28818424/interlaboratory-study-for-the-establishment-of-brazilian-bothrops-reference-venom-and-antivenom-for-potency-evaluation-of-bothrops-antivenom
#1
Humberto Pinheiro de Araújo, Elizabeth Porto Reis Lucas, Wlamir Corrêa de Moura, Celia de Fátima Barbosa, Raquel Joane Rodrigues, Josefina Farina Morais, Joseana Zaja Almada, Barbara Carino Guimarães, Antonio Eugenio Castro Cardoso de Almeida, Maria Aparecida Affonso Boller
A collaborative study was performed for the establishment of the 5th lot of Brazilian Bothrops Reference Venom and the 1st lot of Brazilian Bothrops Reference Antivenom. All Brazilian manufacturers of Antibothrops Immunoglobulins and the National Control Laboratory participated of the study. The declared potency of the 5th lot of the Bothrops Reference Venom is 40.29 μg/0.5 ml, and the potency of the 1st lot of Bothrops Reference Antivenom is 6.51 mg/ml. For the potency evaluation of Bothrops Reference Venom the inter assay precision (gCV) was 3...
August 14, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28817241/association-between-vitamin-d-deficiency-and-heart-failure-risk-in-the-elderly
#2
Catarina Magalhães Porto, Vanessa De Lima Silva, João Soares Brito da Luz, Brivaldo Markman Filho, Vera Magalhães da Silveira
AIMS: The aim of this study was to evaluate the association between vitamin D deficiency and risk of heart failure in elderly patients of cardiology outpatient clinics. METHODS AND RESULTS: A cross-sectional study with an analytical approach was employed. Clinical data were collected from the elderly from August 2015 to February 2016. The dependent variable was the risk of heart failure; the independent variable was vitamin D deficiency; and intervening factors were age, gender, education, ethnicity, hypertension, diabetes mellitus, hypothyroidism, renal failure, dementia, stroke, dyslipidaemia, depression, smoking, alcoholism, obesity, andropause, and cardiac arrhythmia...
August 17, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28809798/socioeconomic-inequalities-in-green-space-quality-and-accessibility-evidence-from-a-southern-european-city
#3
Elaine Hoffimann, Henrique Barros, Ana Isabel Ribeiro
Background: The provision of green spaces is an important health promotion strategy to encourage physical activity and to improve population health. Green space provision has to be based on the principle of equity. This study investigated the presence of socioeconomic inequalities in geographic accessibility and quality of green spaces across Porto neighbourhoods (Portugal). Methods: Accessibility was evaluated using a Geographic Information System and all the green spaces were audited using the Public Open Space Tool...
August 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28809744/effect-of-vitamin-d-serum-levels-and-gc-gene-polymorphisms-in-liver-fibrosis-due-to-chronic-hepatitis-c
#4
Laura A Azevedo, Ursula Matte, Themis R Silveira, Jacqueline W Bonfanti, Juliana P Bruch, Mário R Álvares-da-Silva
INTRODUCTION AND AIM: Vitamin D has been associated with chronic liver diseases and low vitamin levels may contribute to progression of chronic hepatitis C. The aim of this study was to evaluate the influence of vitamin D serum levels and GC gene polymorphisms in the severity of liver fibrosis in patients with chronic hepatitis C genotype 1. MATERIAL AND METHODS: Cross-sectional study that enrolled 132 adult patients with chronic hepatitis C genotype 1 attended at the outpatient Clinic of Gastroenterology Division at Hospital de Clínicas de Porto Alegre...
August 8, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28803786/distribution-of-hla-a-b-and-drb1-antigenic-groups-and-haplotypes-from-the-brazilian-bone-marrow-donor-registry-redome
#5
Leandro Torres, Luis Fernando da Silva Bouzas, Alexandre Almada, Luis Cristovão Moraes de Sobrino Porto, Eliana Abdelhay
To improve assistance for patients awaiting a bone marrow transplant from an unrelated donor, it is important to genetically characterize the Brazilian volunteer bone marrow donors registry (REDOME). Our objective was to describe the antigenic groups and haplotype frequencies of HLA-A, HLA-B and HLA-DRB1 in the five regions of Brazil and by self-reported ethnicity groups using the REDOME data. Our study included 3,038,286 individuals. HLA antigenic groups and haplotype frequencies were estimated using an Expectation-Maximization (EM) algorithm...
August 10, 2017: Human Immunology
https://www.readbyqxmd.com/read/28797856/neuropathic-pain-after-breast-cancer-treatment-characterization-and-risk-factors
#6
Susana Pereira, Filipa Fontes, Teresa Sonin, Teresa Dias, Maria Fragoso, José Castro-Lopes, Nuno Lunet
CONTEXT: Neuropathic pain (NP) may be an important contributor to the morbidity burden of breast cancer. OBJECTIVES: We aimed to quantify the incidence of NP in the first year after diagnosis of breast cancer, and to identify its main determinants. METHODS: We performed a prospective cohort study including 506 patients with incident breast cancer, recruited at the Portuguese Institute of Oncology of Porto, and followed for one year; patients with incident NP were additionally evaluated when this condition was diagnosed and after six months, to identify chronic NP...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28793129/clinical-characteristics-of-women-with-gestational-diabetes-comparison-of-two-cohorts-enrolled-20-years-apart-in-southern-brazil
#7
Angela Jacob Reichelt, Letícia Schwerz Weinert, Livia Silveira Mastella, Vanessa Gnielka, Maria Amélia Campos, Vânia Naomi Hirakata, Maria Lúcia Rocha Oppermann, Sandra Pinho Silveiro, Maria Inês Schmidt
CONTEXT AND OBJECTIVE: The prevalence and characteristics of gestational diabetes mellitus (GDM) have changed over time, reflecting the nutritional transition and changes in diagnostic criteria. We aimed to evaluate characteristics of women with GDM over a 20-year interval. DESIGN AND SETTING: Comparison of two pregnancy cohorts enrolled in different periods, in university hospitals in Porto Alegre, Brazil: 1991 to 1993 (n = 216); and 2009 to 2013 (n = 375). METHODS: We applied two diagnostic criteria to the cohorts: International Association of Diabetes and Pregnancy Study Groups (IADPSG)/World Health Organization (WHO); and National Institute for Health and Care Excellence (NICE)...
July 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28765729/new-species-records-of-culicoides-biting-midges-diptera-ceratopogonidae-for-the-state-of-rond%C3%A3-nia-in-brazilian-amazon
#8
Luis Paulo Costa Carvalho, Emanuelle de Sousa Farias, Luiz Herman Soares Gil, Felipe Arley Costa Pessoa, Jansen Fernandes Medeiros
BACKGROUND: Culicoides biting midges are small insects that are proven vectors of pathogens that cause disease in animals and humans. There are 1,368 species of Culicoides in the world, including 149 species in Brazil and 122 species in the Brazilian Amazon Basin. This study documents specimens that were collected between 2013 and 2015 in the municipalities of Alvorada d'Oeste, Buritis, Cacoal, Costa Marques, Espigão d'Oeste, Guajará-Mirim, Pimenta Bueno, Porto Velho and São Francisco Guaporé...
2017: Biodiversity Data Journal
https://www.readbyqxmd.com/read/28763428/cmv-infection-in-pediatric-severe-ulcerative-colitis-a-multicenter-study-from-the-pediatric-ibd-porto-group-of-espghan
#9
Shlomi Cohen, Christine Martinez-Vinson, Marina Aloi, Dan Turner, Amit Assa, Lissy de Ridder, Victorien M Wolters, Tim de Meij, Patrizia Alvisi, Jiri Bronsky, Uri Kopylov
BACKGROUND: Data on the clinical course and outcomes of pediatric patients with cytomegalovirus (CMV) infection complicating acute severe ulcerative colitis (ASC) are very limited. The aim of our study was to compare outcomes of children with ASC who were CMV-positive or CMV-negative. METHODS: This was a multicenter retrospective case-controlled study, from centers affiliated with the Pediatric IBD Porto Group of ESPGHAN. We included CMV -positive children hospitalized for ASC and compared their colectomy rate during hospitalization and up to 1 year thereafter, matched with CMV-negative controls...
July 31, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28762147/pahs-in-water-and-surface-sediments-from-douro-river-estuary-and-porto-atlantic-coast-portugal-impacts-on-human-health
#10
Maria João Rocha, José Luís Dores-Sousa, Catarina Cruzeiro, Eduardo Rocha
This study investigated the presence of 16 priority polycyclic aromatic compounds (PAHs) in waters from the Douro River estuary and nearby Atlantic seacoast, which both bath the Porto metropolis. In the area, there is an oil refinery, an important harbour, an intense maritime traffic, small marinas and highly inhabited cities. For the analysis of PAHs, water samples were taken from four sampling sites, at six different times of the year (2011), and extracted by solid-phase extraction (dissolved fraction) and by ultrasound technique (suspended fraction), before their quantification by gas chromatography-mass spectrometry...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28760367/effects-of-metformin-on-endometrial-cancer-systematic-review-and-meta-analysis
#11
REVIEW
Cinthia G Meireles, Sidney A Pereira, Luciana P Valadares, Daniela F Rêgo, Luiz A Simeoni, Eliete N S Guerra, Adriana Lofrano-Porto
BACKGROUND: Endometrial cancer is one of the most common gynecological cancers, which is frequently preceded by atypical endometrial hyperplasia, a premalignant lesion. Metformin, an antidiabetic drug, has emerged as a new adjunctive strategy for different cancer types, including endometrial cancer. This systematic review and meta-analysis aimed to evaluate the effects of metformin in atypical endometrial hyperplasia and endometrial cancer patients. METHODS: The search was conducted on January 2017 and the articles were collected in Cochrane, LILACS, PubMed, Scopus and Web of Science...
July 28, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28753103/effect-of-alcohol-consumption-on-clinical-attachment-loss-progression-in-an-urban-population-from-south-brazil-a-5-years-longitudinal-study
#12
Marcius C Wagner, Alex N Haas, Rui V Oppermann, Cassiano K Rosing, Jasim M Albandar, Cristiano Susin
OBJECTIVES: To investigate the impact of alcohol consumption on clinical attachment loss (CAL) progression over a period of 5-years. METHODS: A multistage probability sampling strategy was used to draw a representative sample of the metropolitan area of Porto Alegre, Brazil. 502 individuals (209 males and 293 females) who at baseline were 18-65 years old, had no medical history of diabetes, and at least 6 teeth were included in this analysis. Full-mouth six sites per tooth periodontal examinations were conducted at baseline and after 5 years...
July 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28751482/associations-of-anthropometry-since-birth-with-sagittal-posture-at-age-7-in-a-prospective-birth-cohort-the-generation-xxi-study
#13
Fábio A Araújo, Raquel Lucas, Andrew J Simpkin, Jon Heron, Nuno Alegrete, Kate Tilling, Laura D Howe, Henrique Barros
OBJECTIVES: Adult sagittal posture is established during childhood and adolescence. A flattened or hypercurved spine is associated with poorer musculoskeletal health in adulthood. Although anthropometry from birth onwards is expected to be a key influence on sagittal posture design, this has never been assessed during childhood. Our aim was to estimate the association between body size throughout childhood with sagittal postural patterns at age 7. DESIGN: Prospective cohort study...
July 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/28746615/estimated-evolution-of-total-pollutant-gas-emissions-associated-with-vehicle-activity-in-the-metropolitan-region-of-porto-alegre-until-2030
#14
Angel D Chovert, Marcelo F Alonso
In recent years, the majority of economic sectors in Brazil have gone through processes of development and transformation. These processes have led to increases in environmental pollution of all kinds; air pollution being one of the most adverse. The Brazilian transportation sector, which heavily affects the air quality, experienced a significant increase in its vehicle fleet thus provoking larger emissions of pollutant gases, mainly in regions with high population density such as the Metropolitan Region of Porto Alegre (MRPA)...
July 24, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28746528/simple-motor-tasks-independently-predict-extubation-failure-in-critically-ill-neurological-patients
#15
Fernanda Machado Kutchak, Marcelo de Mello Rieder, Josué Almeida Victorino, Carla Meneguzzi, Karla Poersch, Luiz Alberto Forgiarini, Marino Muxfeldt Bianchin
Objective: To evaluate the usefulness of simple motor tasks such as hand grasping and tongue protrusion as predictors of extubation failure in critically ill neurological patients. Methods: This was a prospective cohort study conducted in the neurological ICU of a tertiary care hospital in the city of Porto Alegre, Brazil. Adult patients who had been intubated for neurological reasons and were eligible for weaning were included in the study. The ability of patients to perform simple motor tasks such as hand grasping and tongue protrusion was evaluated as a predictor of extubation failure...
May 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28746451/histopathological-changes-induced-by-hysterothylacium-deardorffoverstreetorum-larvae-nematoda-raphidascarididae-in-priacanthus-arenatus-cuvier-1829-actinopterygii
#16
Bianca Porto Kuraiem, Marcelo Knoff, Nilza Nunes Felizardo, Rodrigo Caldas Menezes, Delir Corrêa Gomes, Sérgio Carmona de São Clemente
Priacanthus arenatus is a fish that occurs in the waters of the western Atlantic Ocean and has few records of parasitism. This study aimed to report histological changes caused by the larvae of Hysterothylacium deardorffoverstreetorum. Between July and December, 2013, 30 samples of P. arenatus were obtained from fish markets in the cities of Niterói and Rio de Janeiro, state of Rio de Janeiro, Brazil. Fragments of spleen, liver, stomach wall and mesentery tissues containing nodules and free parasites were extracted to histopathological study...
April 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/28745749/comparison-of-dairy-desserts-produced-with-a-potentially-probiotic-mixed-culture-and-dispersions-obtained-from-gracilaria-birdiae-and-gracilaria-domingensis-seaweeds-used-as-thickening-agents
#17
Adriana Carneiro Tavares Estevam, Michele Correia de Almeida, Tiago Almeida de Oliveira, Eliane Rolim Florentino, Flávia Carolina Alonso Buriti, Ana Lúcia Figueiredo Porto
Dairy desserts have emerged as interesting options for the incorporation of probiotics, bioactive ingredients and alternative sources of thickeners. This shows an opportunity to investigate the use of Gracilaria seaweeds in the formulation of potentially probiotic dairy desserts. This study aimed to compare the effects of dispersions obtained from Gracilaria domingensis and Gracilaria birdiae used as thickening agents on texture properties of dairy desserts fermented with SAB 440-A, composed of the starter Streptococcus thermophilus and the potential probiotics Bifidobacterium animalis and Lactobacillus acidophilus, and also to study their physicochemical characteristics, microbial viability and sensory acceptability...
July 26, 2017: Food & Function
https://www.readbyqxmd.com/read/28742086/predictive-models-for-estimating-visceral-fat-the-contribution-from-anthropometric-parameters
#18
Claudia Porto Sabino Pinho, Alcides da Silva Diniz, Ilma Kruze Grande de Arruda, Ana Paula Dornelas Leão Leite, Marina de Moraes Vasconcelos Petribú, Isa Galvão Rodrigues
BACKGROUND: Excessive adipose visceral tissue (AVT) represents an independent risk factor for cardiometabolic alterations. The search continues for a highly valid marker for estimating visceral adiposity that is a simple and low cost tool able to screen individuals who are highly at risk of being viscerally obese. The aim of this study was to develop a predictive model for estimating AVT volume using anthropometric parameters. OBJECTIVE: Excessive adipose visceral tissue (AVT) represents an independent risk factor for cardiometabolic alterations...
2017: PloS One
https://www.readbyqxmd.com/read/28722484/consumer-perceptions-of-the-safety-of-ready-to-eat-foods-in-retail-food-store-settings
#19
Katrina Levine, Mary Yavelak, John B Luchansky, Anna C S Porto-Fett, Benjamin Chapman
To better understand how consumers perceive food safety risks in retail food store settings, a survey was administered to 1,041 nationally representative participants who evaluated possible food safety risks depicted in selected photographs and self-reported their perceptions, attitudes, and behaviors. Participants were shown 12 photographs taken at retail stores portraying either commonly perceived or actual food safety contributing factors, such as cross-contamination, product and equipment temperatures, worker hygiene, and/or store sanitation practices...
July 19, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28720962/minimally-processed-beetroot-waste-as-an-alternative-source-to-obtain-functional-ingredients
#20
Anne Porto Dalla Costa, Vanessa Stahl Hermes, Alessandro de Oliveira Rios, Simone Hickmann Flôres
Large amounts of waste are generated by the minimally processed vegetables industry, such as those from beetroot processing. The aim of this study was to determine the best method to obtain flour from minimally processed beetroot waste dried at different temperatures, besides producing a colorant from such waste and assessing its stability along 45 days. Beetroot waste dried at 70 °C originates flour with significant antioxidant activity and higher betalain content than flour produced from waste dried at 60 and 80 °C, while chlorination had no impact on the process since microbiological results were consistent for its application...
June 2017: Journal of Food Science and Technology
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