keyword
https://read.qxmd.com/read/38537226/can-platelet-activation-markers-predict-preeclampsia-and-or-its-severity
#1
JOURNAL ARTICLE
Tuğçe Arslanoğlu, Kübra Kurt-Bilirer, Nihal Çallıoğlu, Selvi Aydın-Şenel, Işıl Turan-Bakırcı, İklil N Koç-Erol, Emre Kar, Zeliha Bayram, Ibrahim Polat
OBJECTIVE: This study aimed to evaluate the value of platelet activation markers in predicting preeclampsia and its severity. Preeclampsia is a serious pregnancy complication that affects 3-5% of pregnancies and can lead to significant morbidity and mortality for both the mother and the fetus. METHODS: The study included 99 patients diagnosed with preeclampsia and 60 healthy pregnant women as a control group. Platelet activation markers such as mean platelet volume (MPV), platelet distribution width (PDW), platelet count, and plateletcrit were evaluated along with other clinical parameters...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38536953/fetoscopic-laser-coagulation-for-twin-to-twin-transfusion-syndrome-a-comparison-of-flexible-1-0-1-2%C3%A2-mm-fetoscopes-with-curved-sheaths-of-2-7-3-3%C3%A2-mm-2-vs-2%C3%A2-mm-fetoscopic-lens-technique-with-sheaths-of-6-6-11-3%C3%A2-mm-2
#2
JOURNAL ARTICLE
Michael Tchirikov, Anja Zühlke, Natalia Schlabritz-Lutsevich, Michael Entezami, Gregor Seliger, Michael Bergner, Weijing Li, Angela Köninger, Andreas Wienke, Rustem Yusupbaev, Andreas D Ebert
OBJECTIVES: Fetoscopic laser coagulation of placental anastomoses is usually performed for a treatment of twin-to-twin transfusion syndrome (TTTS). A common complication of fetoscopic laser coagulation for TTTS is preterm preliminary rupture of fetal membranes (PPROM) aggravating the neonatal outcome significantly. However, use of an flexible 1 mm fetoscope with an curved sheath could reduce iatrogenic damage of the amniotic membrane and improve neonatal outcomes after laser treatment...
March 28, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38536594/pathologic-maternal-and-neonatal-outcomes-associated-with-programmed-embryo-transfer
#3
REVIEW
Kirk P Conrad, Frauke von Versen-Höynck, Valerie L Baker
PURPOSE: In this first of two companion papers, we critically review the evidence recently published in the primary literature, which addresses adverse maternal and neonatal pregnancy outcomes associated with programmed embryo transfer cycles. We next consider whether these pathological pregnancy outcomes might be attributable to traditional risk factors, unknown parental factors, embryo culture, culture duration, or cryopreservation. Finally, in the second companion article, we explore potential etiologies and suggest strategies for prevention...
March 27, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38533951/impact-of-an-impaired-maternal-fetal-environment-on-death-in-children-with-congenital-heart-defects-undergoing-surgery-in-denmark-from-1994-to-2018
#4
JOURNAL ARTICLE
Rasmus Kristensen, Camilla Omann, Charlotte K Ekelund, J William Gaynor, Vibeke E Hjortdal
BACKGROUND: Studies show that an impaired maternal-fetal environment (iMFE) increases the mortality risk in children with single-ventricle congenital heart defects (CHDs). We investigated the impact of an iMFE on death in children with various surgically corrected CHDs. METHODS AND RESULTS: In this nationwide register-based study, we examined the association between an iMFE (including preeclampsia, gestational hypertension, gestational diabetes, maternal smoking during pregnancy) and death in a large cohort of children with surgically corrected CHDs in Denmark (1994-2018)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533148/a-rare-recurrence-of-a-thyroglossal-duct-cyst-accompanied-by-several-postoperative-complications-in-an-eight-year-old-boy-a-case-report
#5
Ethan Dimock, Jithin John, Jatin Ahluwalia, Alise Haddad, Michael Haupert
A thyroglossal duct cyst (TGDC) is a fluid-filled mass in the neck resulting from the persistence of a duct from fetal development that typically regresses spontaneously. When it persists, it is most often removed in a surgical procedure known as a Sistrunk operation. This case study presents the intriguing case of an eight-year-old boy who presented to an otolaryngology clinic with both a recurrence of his TGDC, as well as several postoperative complications, after the Sistrunk operation was performed...
February 2024: Curēus
https://read.qxmd.com/read/38523954/management-of-acute-saddle-pulmonary-embolism-in-pregnancy-following-fetal-surgery
#6
Patrick J Connell, Leonardo A Marquez Roa, Jorge Araujo-Duran, Monica Cheriyan, Sabry Ayad
A 33-year-old gravidity three parity three (G3P3) woman at 34 weeks of pregnancy underwent fetal surgery to repair an open lumbosacral myelomeningocele at 22 weeks gestation and experienced preterm premature rupture of membranes as a result. She developed a saddle pulmonary embolus with signs of right heart strain while on prolonged bed rest. She was treated emergently with aspiration thrombectomy and suprarenal inferior vena cava (IVC) filter placement, followed by an uncomplicated cesarean delivery thereafter...
February 2024: Curēus
https://read.qxmd.com/read/38522950/influence-of-cancer-in-pregnancy-on-obstetric-and-neonatal-outcomes-an-observational-retrospective-cohort-study
#7
JOURNAL ARTICLE
Xuan Huang, Chen Zhang, Jialei Zhu, Yueyan Li, Jing Tang
OBJECTIVE: The study aimed to review the oncological characteristics and treatment of pregnancy-associated cancers and analyze the obstetric and neonatal outcomes to provide evidence-based recommendations for reproductive function preservation, oncological treatment, and obstetric management. METHODS: We conducted an observational retrospective cohort study among pregnant patients with cancer in 7 Chinese tertiary A hospitals from 2003 to 2021. We conducted multiple logistic regression to determine the influence of various factors on preterm birth and small-for-gestational-age infants, log-binomial regression to analyze temporal changes, and χ² tests to explore the effects of cancer type/treatment...
March 11, 2024: Journal of Gynecologic Oncology
https://read.qxmd.com/read/38521500/comparison-of-terbutaline-and-atosiban-as-tocolytic-agents-in-intrauterine-repair-of-myelomeningocele-a-retrospective-cohort-study
#8
JOURNAL ARTICLE
Shirley Andrade Santos, Fernando Souza Nani, Elaine Imaeda de Moura, Diogo Lima de Carvalho, Guilherme Jorge Mattos Miguel, Cristiane Maria Federicci Haddad, Joaquim Edson Vieira, Victor Bunduki, Mário Henrique Burlacchini de Carvalho, Rossana Pulcineli Vieira Francisco, Daniel Dante Cardeal, Hermann Dos Santos Fernandes
BACKGROUND: Myelomeningocele (MMC) is a neural tube defect disease. Antenatal repair of fetal MMC is an alternative to postnatal repair. Many agents can be used as tocolytics during the in utero fetal repair such as β2-agonists and oxytocin receptor antagonists, with possible maternal and fetal repercussions. This study aims to compare maternal arterial blood gas analysis between terbutaline or atosiban, as tocolytic agents, during intrauterine MMC repair. METHODS: Retrospective cohort study...
March 21, 2024: Brazilian Journal of Anesthesiology
https://read.qxmd.com/read/38521344/untreated-combined-persistent-fetal-vasculature-with-coralliform-cataract-in-a-hispanic-21-year-old-male
#9
A Garza-Garza Lucas, Villarreal-Martinez Priscila, Garza-Leon Manuel
Persistent fetal vasculature is a spectrum of ocular abnormalities linked to an incomplete regression of the fetal ocular vasculature. A 21-years old male patient came to the outpatient clinic reporting low vision and strabismus in his left eye since 3 years of age. Ophtalmological examination revealed a normal right eye, while the left eye had a best corrected visual acuity of hand-motion perception, a 30 prism diopters esotropia, a "coralliform" cataract and a vitreous stalk joining the posterior face of the lens and the optic nerve...
March 21, 2024: Archivos de la Sociedad Española de Oftalmología
https://read.qxmd.com/read/38519389/antenatal-administration-of-extracellular-vesicles-derived-from-amniotic-fluid-stem-cells-improves-lung-function-in-neonatal-rats-with-congenital-diaphragmatic-hernia
#10
JOURNAL ARTICLE
Rebeca L Figueira, Naghmeh Khoshgoo, Fabian Doktor, Kasra Khalaj, Tasneem Islam, Nazgol Moheimani, Matisse Blundell, Lina Antounians, Martin Post, Augusto Zani
BACKGROUND: The severity of pulmonary hypoplasia is a main determinant of outcome for babies with congenital diaphragmatic hernia (CDH). Antenatal administration of extracellular vesicles derived from amniotic fluid stem cells (AFSC-EVs) has been shown to rescue morphological features of lung development in the rat nitrofen model of CDH. Herein, we evaluated whether AFSC-EV administration to fetal rats with CDH is associated with neonatal improvement in lung function. METHODS: AFSC-EVs were isolated by ultracentrifugation and characterized by size, morphology, and canonical marker expression...
February 28, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38515378/successful-late-repair-of-truncus-arteriosus-a-single-center-experience
#11
JOURNAL ARTICLE
Mohamed M Elgayar, Mohamed M Mostafa, Mohamed Adel, Hatem Hosny
Background: Truncus arteriosus is a rare congenital heart defect resulting from the failure of the truncus arteriosus to divide during fetal development. It leads to a single outflow tract from the heart and, if left untreated, can be fatal. Late presentation and repair can also increase the risk of pulmonary hypertensive crises, which can lead to morbidity and mortality after repair. Methods: We performed a retrospective study examining outcomes of late-presenting patients who were repaired for this anomaly at our institution...
March 22, 2024: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/38515292/acute-fetal-metabolomic-changes-in-twins-undergoing-fetoscopic-surgery-for-twin-twin-transfusion-syndrome
#12
JOURNAL ARTICLE
Braxton Forde, Samuel Martin, Miki Watanabe-Chailland, Foong-Yen Lim
Fetuses undergo major surgical stress as well as fluid shifts secondary to both twin-twin transfusion (TTTS) as well as the fetoscopic surgery for treatment of TTTS. While the pathophysiology of TTTS is understood, the acute metabolic changes that fetuses experience from fetoscopic surgery are not. We sought to evaluate the changes in recipient metabolomic profile secondary to TTTS surgery. Amniotic fluid was collected at the beginning and end of four TTTS surgical cases performed from 12/2022-2/2023. Samples were immediately processed and evaluated via NMR-based Metabolomics Facility protocol...
March 22, 2024: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://read.qxmd.com/read/38514967/anchoring-device-to-prevent-membrane-detachment-and-preterm-premature-rupture-of-membranes-after-fetal-intervention
#13
JOURNAL ARTICLE
E P Bergh, L K Mann, J H Won, A Nobles, A Johnson, R Papanna
OBJECTIVE: Anchoring the fetal membrane to the uterine wall via a novel suture delivery system could reduce the risk of preterm premature rupture of membranes (PPROM) after fetoscopic surgery. This study assesses the feasibility of using a novel device designed for minimally invasive suturing to anchor fetal membranes to the uterine wall and to close surgical defects after fetoscopy. METHODS: We tested the suturing device both ex vivo and in vivo. In the ex vivo studies, 12-French trocar defects were created with a fetoscope in five specimens of human uterine tissue with fetal membranes attached...
March 21, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38512489/congenitally-corrected-transposition-of-the-great-arteries-in-utero-morphological-spectrum-outcomes-and-pitfalls-in-fetal-diagnosis
#14
JOURNAL ARTICLE
Maria Kavga, Adeolu Banjoko, Esther Poole, John Stickley, Tarak Desai, Paul Miller, Michael Harris, Adrian Crucean, Natasha Khan, Anna N Seale
Congenitally corrected transposition of the great arteries (ccTGA) is a rare malformation with diverse morphology. We assessed features of fetuses with ccTGA and evaluated neonatal and pediatric outcomes. This was a retrospective review of fetuses with ccTGA at Birmingham Women's and Children's Hospital born from 2005 to 2019. Of thirty-six fetuses identified, six had unavailable prenatal data, one was postnatally diagnosed with isomerism and 29 fetuses were evaluated. ccTGA without associated cardiac lesions was found in 28% (8/29), ccTGA with significant VSD in 31% (9/29), ccTGA with pulmonary obstruction in 24% (7/29) and ccTGA with complex anomalies in 17% (5/29)...
March 21, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38505161/our-experience-with-management-of-congenital-urological-pathologies-in-adulthood-what-pediatric-urologists-should-know-and-adult-urologists-adopt-in-pediatric-practice-experience
#15
JOURNAL ARTICLE
Leon Chertin, Binyamin B Neeman, Jawdat Jaber, Guy Verhovsky, Amnon Zisman, Ariel Mamber, Ilan Kafka, Ala Eddin Natsheh, Dmitry Koulikov, Ofer Z Shenfeld, Boris Chertin, Stanislav Koucherov, Amos Neheman
PURPOSE: To summarize our experience in the management of congenital anomalies in the kidney and urinary tract (CAKUT) in adults. MATERIALS AND METHODS: We conducted a retrospective chart review of all adult patients who underwent primary surgical intervention for CAKUT between 1998 and 2021. RESULTS: The study included 102 patients with a median age of 25 (interquartile range, 23-36.5). Of these, 85 (83.3%) patients reported normal prenatal ultrasound, and the remaining 17 (16...
March 2024: Current Urology
https://read.qxmd.com/read/38502848/retroperitoneoscopic-simple-nondismembered-pyeloplasty-with-da-vinci-si-assistance-to-prevent-alignment-shift
#16
JOURNAL ARTICLE
Go Miyano, Hisae Iida, Yu Ebata, Eri Abe, Haruki Kato, Takafumi Mikami, Junya Ishii, Geoffrey J Lane, Atsuyuki Yamataka, Tadaharu Okazaki
Aims: Retroperitoneoscopic simple nondismembered pyeloplasty (SNDP) with da Vinci Si assistance was developed because of a possible risk for alignment shift after retroperitoneoscopic diamond-shaped bypass pyeloplasty (Diamond-Bypass; DP). Outcomes of SNDP and DP were compared. Materials and Methods: For SNDP, a small longitudinal incision is made on the border of the dilated pelvis and narrowed ureter at the ureteropelvic junction (UPJ). Extending this incision toward the pelvis allows identification of mucosa while maintaining the integrity of surrounding tissues that are so thin and fragile that they will not influence lumen alignment...
March 19, 2024: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://read.qxmd.com/read/38502037/length-of-hysterotomy-for-fetal-spina-bifida-repair-is-associated-with-prematurity-risk
#17
JOURNAL ARTICLE
Kanokwaroon Watananirun, Anna M L F Vargas, Simen Vergote, Liesbeth Lewi, Marcelo O L Filippo, Peter McCulloch, Roland Devlieger, Cleisson F A Peralta, Jan Deprest
OBJECTIVE: To investigate whether prenatal repair of spina bifida aperta through mini-hysterotomy results in less prematurity, as compared to standard hysterotomy, when adjusting for known prematurity risks. METHODS: We performed a bi-centric, propensity score matched, controlled study, that is, adjusting for factors earlier reported to result in premature delivery or membrane rupture, in consecutive women having prenatal repair either through stapled hysterotomy or sutured mini-hysterotomy (≤3...
March 19, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38498203/pulmonary-vasculature-development-in-congenital-diaphragmatic-hernia-a-novel-automated-quantitative-imaging-analysis
#18
JOURNAL ARTICLE
Emrah Aydın, Furkan Durmuş, Nilhan Torlak, Marc Oria, Nilgün Güler Bayazıt, Esin Öztürk Işık, Birol Aslanyürek, Jose L Peiro
PURPOSE: Impaired fetal lung vasculature determines the degree of pulmonary hypertension in the congenital diaphragmatic hernia (CDH). This study aims to demonstrate the morphometric measurements that differ in pulmonary vessels of fetuses with CDH. METHODS: Nitrofen-induced CDH Sprague-Dawley rat fetuses were scanned with microcomputed tomography. The analysis of the pulmonary vascular tree was performed with artificial intelligence. RESULTS: The number of segments in CDH was significantly lower than that in the control group on the left (U = 2...
March 18, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38498162/does-overweight-and-obesity-have-an-impact-on-delivery-mode-and-peripartum-outcome-in-breech-presentation-a-frabat-cohort-study
#19
JOURNAL ARTICLE
Lukas Jennewein, Lena Agel, Samira Catharina Hoock, Anna Elisabeth Hentrich, Frank Louwen, Nadja Zander
PURPOSE: Obesity is a worldwide and growing issue affecting women in childbearing age, complicating surgical procedures as well as pregnancy. Through a reduction of not necessarily required cesarean deliveries-for instance in pregnancies with breech presentation-obesity mediated and surgery-associated morbidity might be contained. Date on the impact of maternal BMI in vaginally attempted breech delivery is not existing. To give insight into whether an elevated BMI leads to an increased perinatal morbidity in vaginally intended deliveries out of breech presentation, we analyzed delivery outcome of laboring women with a singleton baby in breech presentation with overweight and obesity (BMI ≥ 25 kg/m2 ) in comparison to women with a BMI of below 25 kg/m2 ...
March 18, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38495654/an-overview-of-arrhythmias-in-pregnancy
#20
REVIEW
Kamala P Tamirisa, Estefania Oliveros, Shweta Paulraj, Adriana C Mares, Annabelle Santos Volgman
Cardiovascular disease significantly jeopardizes pregnancies in the United States, impacting 1% to 4% of pregnancies annually. Among complications, cardiac arrhythmias are prevalent, posing concerns for maternal and fetal health. The incidence of arrhythmias during pregnancy is rising, partly due to advances in congenital heart surgery and a growing population of women with structural heart disease. While most arrhythmias are benign, the increasing prevalence of more serious arrhythmias warrants a proactive approach...
2024: Methodist DeBakey Cardiovascular Journal
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