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https://www.readbyqxmd.com/read/28651372/living-arrangements-disability-and-gender-of-older-adults-among-rural-south-africa
#1
Enid Schatz, Margaret Ralston, Sangeetha Madhavan, Mark A Collinson, F Xavier Gómez-Olivé
Objective: A limited understanding exists of the relationship between disability and older persons' living arrangements in low and middle-income countries (LMICs). We examine the associations between living arrangements, disability, and gender for individuals older than 50 years in rural South Africa. Method: Using the Study on global AGEing and adult health (SAGE) survey and Agincourt Health and socio-Demographic Surveillance System (HDSS) data, we explore older persons' self-reported disability by living arrangements and gender, paying particular attention to various multigenerational arrangements...
June 23, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28649711/point-of-care-ultrasound-in-general-surgery-residency-training-a-proposal-for-milestones-in-graduate-medical-education-ultrasound
#2
Eliza W Beal, Benjamin R Sigmond, Latifa Sage-Silski, Samantha Lahey, Victor Nguyen, David P Bahner
The use of point-of-care ultrasound (US) in the clinical setting has undergone massive growth, although its incorporation into training and practice is variable. Surgeons are interested in using point-of-care US and can incorporate it effectively into clinical practice. However, the current state of point-of-care US training in general surgery is inadequate. The Accreditation Council for Graduate Medical Education introduced the Milestones Project to evaluate resident and fellow performance. Emergency medicine is the only specialty with a point-of-care US milestone...
June 26, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28648130/communication-in-palliative-care-the-applicability-of-the-sage-and-thyme-model-in-singapore
#3
Ang Seng Hock Martin, John Costello, Jane Griffiths
BACKGROUND: Majority of the progress and development in palliative care in the last decade has been improvements in physical aspects of treatment, namely pain and symptom management. Psychosocial aspects of care have improved, although not enough to meet the needs of many patients and family members. This is evident in many parts of the world and notably in Singapore, where palliative care is seen as an emerging medical and nursing specialty. AIM: To discuss the implementation of the SAGE and THYME communication model in a palliative care context...
June 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28646562/argininosuccinate-synthase-1-ass1-a-marker-of-unclassified-hepatocellular-adenoma-and-high-bleeding-risk
#4
Elodie Henriet, Aya Abou Hammoud, Jean-William Dupuy, Benjamin Dartigues, Zakaria Ezzoukry, Nathalie Dugot-Senant, Thierry Leste-Lasserre, Nestor Pallares-Lupon, Macha Nikolski, Brigitte Le Bail, Jean-Frédéric Blanc, Charles Balabaud, Paulette Bioulac-Sage, Anne-Aurélie Raymond, Frédéric Saltel
Hepatocellular adenomas (HCA) are rare benign tumors divided into three main subgroups defined by patho-molecular features, HNF1A (H-HCA), mutated β-catenin (b-HCA) and inflammatory (IHCA). In the case of unclassified HCA (UHCA), which are currently identified by default, a high risk of bleeding remains a clinical issue. The objective of this study was to explore UHCA proteome with the aim to identify specific biomarkers. Following dissection of the tumoral (T) and non-tumoral (NT) tissue on formalin-fixed paraffin-embedded (FFPE) from HCA tissue sections using laser capture methodology, we performed mass spectrometry analysis to compare T and NT protein expression levels in HCA, H-HCA, IHCA, b-HCA, UHCA and focal nodular hyperplasia...
June 23, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28643072/sages-guidelines-for-the-use-of-laparoscopy-during-pregnancy
#5
Jonathan P Pearl, Raymond R Price, Allison E Tonkin, William S Richardson, Dimitrios Stefanidis
No abstract text is available yet for this article.
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28643067/sages-endoluminal-treatments-for-gerd
#6
Jonathan Pearl, Eric Pauli, Brian Dunkin, Dimitrios Stefanidis
No abstract text is available yet for this article.
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28643060/sages-technology-and-value-assessment-committee-safety-and-effectiveness-analysis-on-immunofluorescence-in-the-operating-room-for-biliary-visualization-and-perfusion-assessment
#7
Bryan J Sandler, Danny Sherwinter, Lucian Panait, Richard Parent, Jennifer Schwartz, David Renton
No abstract text is available yet for this article.
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28639535/corrigendum
#8
(no author information available yet)
Cawley N, Tur C, Prados F, et al. Spinal cord atrophy as a primary outcome measure in phase II trials of progressive multiple sclerosis. Mult Scler. Epub ahead of print 18 May 2017. DOI: 10.1177/1352458517709954. On page 9 of this article, the Declaration of Conflicting Interests and Funding statements were incorrect. The correct declarations are shown below. Declaration of Conflicting Interests The author(s) declared the following potential conflicts of interest with respect to the research, authorship and/or publication of this article: A...
June 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28639170/bistability-and-asynchrony-in-a-boolean-model-of-the-l-arabinose-operon-in-escherichia-coli
#9
Andy Jenkins, Matthew Macauley
The lactose operon in Escherichia coli was the first known gene regulatory network, and it is frequently used as a prototype for new modeling paradigms. Historically, many of these modeling frameworks use differential equations. More recently, Stigler and Veliz-Cuba proposed a Boolean model that captures the bistability of the system and all of the biological steady states. In this paper, we model the well-known arabinose operon in E. coli with a Boolean network. This has several complex features not found in the lac operon, such as a protein that is both an activator and repressor, a DNA looping mechanism for gene repression, and the lack of inducer exclusion by glucose...
June 21, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28639045/passing-the-fundamentals-of-endoscopic-surgery-fes-exam-linking-specialty-choice-and-attitudes-about-endoscopic-surgery-to-success
#10
Aimee K Gardner, Michael B Ujiki, Brian J Dunkin
INTRODUCTION: Previous work has shown that up to 30% of graduating surgery residents fail the fundamentals of endoscopic surgery (FES) exam. This study investigated the extent to which FES pass rates differ in a specific sample of individuals who have chosen a career in GI surgery and to examine the relationships between FES performance and confidence in performing flexible endoscopy. METHODS: Fellows attending the 2016 SAGES Flexible Endoscopy Course were invited to complete the FES manual skills examination...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28635261/novel-protein-based-solid-biosensor-for-determining-pro-oxidant-activity-of-phenolic-compounds
#11
Esin Akyüz, Kevser Sözgen Başkan, Esma Tütem, Reşat Apak
To develop a protein‒based biosensor measuring the pro-oxidant activities of phenolic compounds, egg white proteins were precipitated with calcium chloride to obtain an insoluble calcium proteinate complex. This biosensor was used for the determination of Cu(II)‒induced pro-oxidant activity of antioxidants such as gallic acid, catechin, epicatechin, quercetin, chlorogenic acid and myricetin, and ascorbic acid. This assay involved the reduction of Cu(II) ions to Cu(I) by antioxidant compounds (simultaneously giving rise to reactive oxygen species) and binding of the formed Cu(I) to the solid biosensor...
June 21, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28634631/sages-university-masters-program-a-structured-curriculum-for-deliberate-lifelong-learning
#12
Daniel B Jones, Dimitrios Stefanidis, James R Korndorffer, Justin B Dimick, Brian P Jacob, Linda Schultz, Daniel J Scott
BACKGROUND: Postgraduate training has been haphazard to date. Surgeons have relied on attendance to annual meetings and multiple choice study guides to demonstrate maintenance of certification and continuing medical education. METHODS: SAGES held a retreat to develop the concept and scope of the Masters Program. Surveys were sent to SAGES members to guide curriculum development and selection of anchoring operations. RESULTS: SAGES has developed an educational curriculum across eight domains (Acute Care, Biliary, Bariatric, Colorectal, Hernia, Foregut, Flex Endoscopy, and Robotic Surrey) incorporating SAGES educational materials and guidelines, social media, coaching and mentoring...
June 20, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28633661/prevalence-of-arthritis-according-to-age-sex-and-socioeconomic-status-in-six-low-and-middle-income-countries-analysis-of-data-from-the-world-health-organization-study-on-global-ageing-and-adult-health-sage-wave-1
#13
Sharon L Brennan-Olsen, S Cook, M T Leech, S J Bowe, P Kowal, N Naidoo, I N Ackerman, R S Page, S M Hosking, J A Pasco, M Mohebbi
BACKGROUND: In higher income countries, social disadvantage is associated with higher arthritis prevalence; however, less is known about arthritis prevalence or determinants in low to middle income countries (LMICs). We assessed arthritis prevalence by age and sex, and marital status and occupation, as two key parameters of socioeconomic position (SEP), using data from the World Health Organization Study on global AGEing and adult health (SAGE). METHODS: SAGE Wave 1 (2007-10) includes nationally-representative samples of older adults (≥50 yrs), plus smaller samples of adults aged 18-49 yrs...
June 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28633052/disinfection-efficiencies-of-sage-and-spearmint-essential-oils-against-planktonic-and-biofilm-staphylococcus-aureus-cells-in-comparison-with-sodium-hypochlorite
#14
Dimitrios Vetas, Eleni Dimitropoulou, Gregoria Mitropoulou, Yiannis Kourkoutas, Efstathios Giaouris
Staphylococcus aureus causes human infections and foodborne intoxications. This study explored the potential antibacterial actions of sage and spearmint essential oils (EOs) against both its planktonic and biofilm cells, in comparison with sodium hypochlorite (NaOCl), a commonly applied chemical sanitizer. Initially, the minimum inhibitory and bactericidal concentrations (MICs, MBCs) of each plant mixture were determined against planktonic cultures, following growth at 30°C for 24h. Stationary phase planktonic bacteria were then individually exposed for 6min to either each EO (applied at 1-2×MBC; 2...
June 8, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28632988/solid-sampling-with-a-diode-laser-for-portable-ambient-mass-spectrometry
#15
Yeni P Yung, Raveendra Wickramasinghe, Anu Vaikkinen, Tiina Johanna Kauppila, Igor V Veryovkin, Luke Hanley
A handheld diode laser is implemented for solid sampling in portable ambient mass spectrometry (MS). Specifically, a pseudo-continuous wave battery-powered surgical laser diode is employed for portable laser diode thermal desorption (LDTD) at 940 nm and compared with nanosecond pulsed laser ablation at 2940 nm. Postionization is achieved in both cases using atmospheric pressure photoionization (APPI). The laser ablation atmospheric pressure photoionization (LAAPPI) and LDTD-APPI mass spectra of sage leaves (Salvia officinalis) using a field-deployable quadrupole ion trap MS display many similar ion peaks, as do the mass spectra of membrane grown biofilms of Pseudomonas aeruginosa...
June 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28624414/corneal-kindled-c57bl-6-mice-exhibit-saturated-dentate-gyrus-long-term-potentiation-and-associated-memory-deficits-in-the-absence-of-overt-neuron-loss
#16
Gregory J Remigio, Jaycie L Loewen, Sage Heuston, Colin Helgeson, H Steve White, Karen S Wilcox, Peter J West
Memory deficits have a significant impact on the quality of life of patients with epilepsy and currently no effective treatments exist to mitigate this comorbidity. While these cognitive comorbidities can be associated with varying degrees of hippocampal cell death and hippocampal sclerosis, more subtle changes in hippocampal physiology independent of cell loss may underlie memory dysfunction in many epilepsy patients. Accordingly, animal models of epilepsy or epileptic processes exhibiting memory deficits in the absence of cell loss could facilitate novel therapy discovery...
June 15, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28623842/what-are-they-thinking-a-national-study-of-stability-and-change-in-divorce-ideation
#17
Alan J Hawkins, Adam M Galovan, Steven M Harris, Sage E Allen, Sarah M Allen, Kelly M Roberts, David G Schramm
This study reports on a nationally representative sample of married individuals ages 25-50 (N = 3,000) surveyed twice (1 year apart) to investigate the phenomenon of divorce ideation, or what people are thinking when they are thinking about divorce. Twenty-eight percent of respondents had thought their marriage was in serious trouble in the past but not recently. Another 25% had thoughts about divorce in the last 6 months. Latent Class Analysis revealed three distinct groups among those thinking about divorce at Time 1: soft thinkers (49%), long-term-serious thinkers (45%), and conflicted thinkers (6%)...
June 17, 2017: Family Process
https://www.readbyqxmd.com/read/28620068/x-box-binding-protein-1-dependent-plasma-cell-responses-limit-the-development-of-atherosclerosis
#18
Andrew P Sage, Meritxell Nus, Jayashree Bagchi Chakraborty, Dimitrios Tsiantoulas, Stephen A Newland, Alison J Finigan, Leanne Masters, Christoph J Binder, Ziad Mallat
Rationale: Diverse B cell responses and functions may be involved in atherosclerosis. Protective antibody responses, such as those against oxidized lipid epitopes, are thought to mainly derive from T cell-independent innate B cell subsets. In contrast, both pathogenic and protective roles have been associated with T cell-dependent antibodies and their importance in both humans and mouse models is still unclear. Objective: To specifically target antibody production by plasma cells and determine the impact on atherosclerotic plaque development in mice with and without CD4+ T cells...
June 15, 2017: Circulation Research
https://www.readbyqxmd.com/read/28619996/farnesoid-x-receptor-and-liver-x-receptor-ligands-initiate-formation-of-coated-platelets
#19
Amanda J Unsworth, Alexander P Bye, Dionne S Tannetta, Michael J R Desborough, Neline Kriek, Tanya Sage, Harriet E Allan, Marilena Crescente, Parveen Yaqoob, Timothy D Warner, Chris I Jones, Jonathan M Gibbins
OBJECTIVES: The liver X receptors (LXRs) and farnesoid X receptor (FXR) have been identified in human platelets. Ligands of these receptors have been shown to have nongenomic inhibitory effects on platelet activation by platelet agonists. This, however, seems contradictory with the platelet hyper-reactivity that is associated with several pathological conditions that are associated with increased circulating levels of molecules that are LXR and FXR ligands, such as hyperlipidemia, type 2 diabetes mellitus, and obesity...
June 15, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28619795/genome-sequence-of-leuconostoc-citreum-dmw_111-isolated-from-wild-drosophila
#20
Sage M Wright, Courtney Carroll, Amber Walters, Peter D Newell, John M Chaston
Isolates of the lactic acid bacterium Leuconostoc citreum are a major part of fermentation processes, especially in Korean kimchi. Here, we present the genome of L. citreum DmW_111, isolated from wild Drosophila melanogaster; analysis of this genome will expand the diversity of genome sequences for non-Lactobacillus spp. isolated from D. melanogaster.
June 15, 2017: Genome Announcements
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