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https://www.readbyqxmd.com/read/28632246/declines-noted-in-cognitive-processes-and-association-with-achievement-among-children-with-leukemia
#1
Kathleen C Insel, Marilyn J Hockenberry, Lynette L Harris, Kari M Koerner, Zhenqiang Lu, Kristin B Adkins, Olga A Taylor, Patricia M Gundy, Ida M Moore
PURPOSE/OBJECTIVES: To assess change in specific cognitive processes during treatment with chemotherapy only among children with acute lymphoblastic leukemia (ALL). 
. DESIGN: A prospective, repeated measures design.
. SETTING: Pediatric oncology treatment centers at Banner-University Medical Center Tucson/Banner Children's-Diamond Medical Center (University of Arizona) and Texas Children's Cancer and Hematology centers (Baylor College of Medicine) in Houston...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28576259/-adolescents-and-young-adults-with-acute-lymphoblastic-leukemia-a-specific-management
#2
Nicolas Boissel, Stéphane Ducassou
The acute lymphoblastic leukemia (ALL) is one of the first cancer for which emerged the particularity of the adolescent and young adult population. After decades of poorly concerted approaches, adult and pediatric haematologists found out that adolescents treated according to pediatric approaches had a better outcome than those treated in adult protocols. Therefore, pediatric-inspired therapies have been successfully implemented in the young adult population, leading to decreased criteria for allogeneic stem cell transplantation...
May 30, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28575176/global-oncofertility-index-data-gap-slows-progress
#3
Saskia F de Roo, Alexandra S Rashedi, Catharina C M Beerendonk, Antoinette Anazodo, Anne Marie de Man, Willianne L D M Nelen, Teresa K Woodruff
The number of pediatric and young adult cancer survivors is increasing globally due to earlier diagnostics and expansion of targeted chemo- and biologic-based therapeutics. As a consequence, cancer-related infertility and reproductive hormone loss is of increasing concern for both male and female survivors. We attempted to estimate the reproductive loss in oncofertility-practicing countries and to develop a global oncofertility index (OFI). This would allow an accounting of the level of urgency of the issue and would provide national comparisons of fertility loss, which differ based on the prevalence and/or diagnosis frequency and treatment variables by countries or region...
May 30, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28561716/breast-cancer-after-childhood-adolescent-and-young-adult-cancer-it-s-not-just-about-chest-radiation
#4
David Hodgson, Flora van Leeuwen, Andrea Ng, Lindsay Morton, Tara O Henderson
Women who have been treated for a childhood, adolescent, or young adult cancer are at an increased risk for developing breast cancer at a young age, and breast cancer accounts for the most common subsequent malignant neoplasm among female childhood and adolescent cancer survivors. Risk of breast cancer in these survivors appears to be a multifaceted relationship between constitutional factors, exposures to radiation therapy (RT) and chemotherapy, and genetic predisposition. Given the significant morbidities and mortality associated with a breast cancer diagnosis, it is imperative that health care providers understand the risks, biology and genetics, recommended surveillance guidelines for early detection, and potential prevention strategies for women who have survived pediatric and young adult cancer...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28557375/identifying-metrics-of-success-for-transitional-care-practices-in-childhood-cancer-survivorship-a-qualitative-study-of-survivorship-providers
#5
Karim Thomas Sadak, Joseph P Neglia, David R Freyer, Eileen Harwood
BACKGROUND: Long-term survival in childhood cancer is excellent. Most survivors will have a therapy-related chronic condition, yet very few receive survivor-focused care as they transition from adolescence to young adulthood. The purpose of this study is to identify indicators of success in current transitional care practices for young adult survivors of childhood cancer as defined by all members of survivorship care teams. PROCEDURE: An exploratory, phenomenologic qualitative study was conducted with key informants from medical teams involved in transitional care of childhood cancer survivors...
May 30, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28546377/respiratory-care-considerations-in-the-childhood-cancer-patient
#6
Lama Elbahlawan, K Jason Rains, Dennis C Stokes
This article reviews the common pulmonary complications seen in the pediatric oncology population and our approach to diagnosis, management, and therapy considerations in this specialized population, including patients receiving chemotherapy, radiation, and hematopoietic stem cell transplantation. Although infections cause the most significant complications in this population, non-infectious complications, including acute lung injury from chemotherapy or radiation, idiopathic interstitial pneumonia, diffuse alveolar hemorrhage, bronchiolitis obliterans, and cryptogenic organizing pneumonia, also occur commonly...
June 2017: Respiratory Care
https://www.readbyqxmd.com/read/28541785/long-term-follow-up-consultation-after-childhood-cancer-in-the-rh%C3%A3-ne-alpes-region-of-france-feedback-from-adult-survivors-and-their-general-practitioners
#7
Claire Berger, Léonie Casagranda, Cécile Faure-Conter, Claire Freycon, Florentina Isfan, Aurélie Robles, Béatrice Trombert-Paviot, Isabelle Guichard, Isabelle Durieu, Pascal Cathebras
PURPOSE: We evaluated the satisfaction of adult survivors of childhood cancers and their general practitioners (GP) after a long-term consultation. METHODS: The first Long-term Follow-up Study in Oncology (SALTO1) is a prospective cohort study of survivors of childhood cancers (except leukemia) diagnosed between 1987 and 1992 in the Rhône-Alpes and Auvergne regions of France. Of the 481 patients eligible for the study, 150 participated in a long-term consultation with a pediatric oncologist and an internist, after which survivors and their GPs received long-term plans and recommendations based on consultation findings...
May 25, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28539897/long-term-effects-of-haematopoietic-stem-cell-transplantation-after-pediatric-cancer-a-qualitative-analysis-of-life-experiences-and-adaptation-strategies
#8
Magali Lahaye, Isabelle Aujoulat, Christiane Vermylen, Bénédicte Brichard
Haematopoietic stem cell transplantation (HSCT) improves the survival rate of children and adolescents with malignant and non-malignant conditions; however, the physical, psychological and social burden of such a procedure is considerable both during and after treatment. The present qualitative study investigated the long-term effects of HSCT after pediatric cancer. Thirty adolescent and young adult (AYA) survivors (Mage = 23.61 years, SD = 5.21) participated in individual interviews and were invited to speak about their life experiences following their treatment and strategies they use to deal with their past medical experiences and the long-term sequelae...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28534144/coordination-of-care-in-survivorship-after-treatment-of-hematological-malignancies-the-journey-is-not-over-yet
#9
REVIEW
Catherine J Lee, Lori S Muffly
The number of adult survivors of hematologic malignancies is steadily growing. This population is at moderate to high risk for cancer survivorship issues including physical and psychosocial sequelae of intensive cancer therapies. Although cancer survivorship is a growing field in pediatric and solid tumor oncology, survivorship care and research has often been overlooked in the hematologic malignancies. In this review, we focus specifically on survivorship issues related to adult patients with hematologic malignancies and provide commentary on the role of cancer survivorship, proposed survivorship care models, and the economic and health policy obstacles associated with moving the cancer survivorship field forward in this very important patient population...
May 22, 2017: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/28478851/-having-cancer-was-awful-but-also-something-good-came-out-post-traumatic-growth-among-adult-survivors-of-pediatric-and-adolescent-cancer
#10
Eduardo R Zamora, Jaehee Yi, Jesmin Akter, Jonghee Kim, Echo L Warner, Anne C Kirchhoff
PURPOSE: The cancer experience may cultivate positive psychological changes that can help reduce distress during adult survivors of childhood and adolescent cancer life course. The aim of this study is to examine the positive impact of cancer in adult survivors utilizing posttraumatic growth as a guiding framework. METHOD: Participants were identified and recruited through the Utah Cancer Registry. Eligible cases were diagnosed with cancer age ≤20 years from 1973 to 2009, born in Utah, and were age ≥18 at study...
June 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28458460/childbirth-and-fertility-preservation-in-childhood-and-adolescent-cancer-patients-a-second-national-survey-of-japanese-pediatric-endocrinologists
#11
Yoko Miyoshi, Tohru Yorifuji, Reiko Horikawa, Ikuko Takahashi, Keisuke Nagasaki, Hiroyuki Ishiguro, Ikuma Fujiwara, Junko Ito, Mari Oba, Hiroyuki Fujisaki, Masashi Kato, Chikako Shimizu, Tomoyasu Kato, Kimikazu Matsumoto, Haruhiko Sago, Tetsuya Takimoto, Hiroshi Okada, Nao Suzuki, Susumu Yokoya, Tsutomu Ogata, Keiichi Ozono
Although existing guidelines recommend long-term follow-up of childhood cancer survivors (CCSs), their fertility has not been fully investigated in Japan. To address this issue, we organized a working panel consisting of medical specialists in foundation hospitals. We conducted questionnaire surveys targeting pediatric endocrinologists regarding reproduction in pediatric and adolescent cancer patients in collaboration with the CCS committee of the Japanese Society for Pediatric Endocrinology (JSPE). The first questionnaire was sent to 178 directors or councilors of the JSPE, and the second was sent to those who had provided answers on their experience with childbirth or fertility preservation...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/28455130/a-nonsurgical-approach-to-adolescent-breast-asymmetry-using-external-prostheses
#12
Carolyn M Pike, Joseph M Firriolo, Nicole C Ontiveros, Sarada P Kuchibhotla, Olivia K Oppel, Lauren C Monoxelos, Arin K Greene, Brian I Labow
PURPOSE: Currently, there are few nonsurgical treatment options for pediatric patients with developmental breast asymmetry. Our group established a partnership with a prosthetic unit within a local oncology center to provide custom-fit breast prostheses for young women with breast asymmetry. The purpose of this study was to describe the effect of this experience on patients' self-esteem and body image. METHODS: Patients were administered an anonymous satisfaction survey at least 1 month after their first fitting at the prosthetic unit...
April 25, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28453898/electrophysiological-effects-of-anthracyclines-in-adult-survivors-of-pediatric-malignancy
#13
Timothy M Markman, Kathryn Ruble, David Loeb, Allen Chen, Yiyi Zhang, Gary S Beasley, W Reid Thompson, Saman Nazarian
BACKGROUND: Anthracycline use is limited by cardiotoxicity, including arrhythmias and left ventricular (LV) dysfunction. We aim to characterize the association between electrophysiological changes and LV dysfunction. METHODS: A retrospective chart review was conducted, including all 147 pediatric cancer survivors at our institution over 18 years of age and treated with an anthracycline. One hundred thirty-four patients who had at least one electrocardiogram (ECG) and echocardiogram were analyzed...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28453181/understanding-predictors-of-continued-long-term-pediatric-cancer-care-across-the-region-a-report-from-the-consortium-for-new-england-childhood-cancer-survivors
#14
Jennifer J G Welch, Lisa B Kenney, Priya Hirway, G Naheed Usmani, Nina Kadan-Lottick, Satkiran S Grewal, Mary Huang, Heather Bradeen, Jeremy Ader, Lisa Diller, Cindy L Schwartz
BACKGROUND: Many survivors of childhood cancer do not receive recommended longitudinal oncology care. Factors present at the time of childhood cancer diagnosis may identify patients who are vulnerable to poor adherence to follow-up. METHODS: This cohort of survivors of acute lymphoblastic leukemia (ALL) diagnosed from 1996 to 1999 at seven Consortium for New England Childhood Cancer Survivors institutions was evaluated for attendance at oncology clinics at 5 and 10 years from diagnosis...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28426850/second-primary-malignant-neoplasms-and-survival-in-adolescent-and-young-adult-cancer-survivors
#15
Theresa H M Keegan, Archie Bleyer, Aaron S Rosenberg, Qian Li, Melanie Goldfarb
Importance: Although the increased incidence of second primary malignant neoplasms (SPMs) is a well-known late effect after cancer, few studies have compared survival after an SPM to survival of the same cancer occurring as first primary malignant neoplasm (PM) by age. Objective: To assess the survival impact of SPMs in adolescents and young adults (AYAs) (15-39 years) compared with that of pediatric (<15 years) and older adult (≥40 years) patients with the same SPMs...
April 20, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28425203/educational-and-career-goal-attainments-in-young-adult-childhood-cancer-survivors
#16
Lisa Bashore, Emma Breyer
PURPOSE: Examine the educational and career outcomes of young adult childhood cancer survivors. DESIGN AND METHODS: Descriptive study design using a survey sent to 336 survivors. Quantitative and qualitative data were analyzed separately. RESULTS: Only 50 completed surveys were returned. Having a central nervous system tumor and radiation were associated with physical impairments. Four themes also emerged: future as medical professionals, dreams fallen short, peer relationships, and positive outlook on life...
April 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28410182/parent-and-health-care-provider-perceptions-for-development-of-a-web-based-weight-management-program-for-survivors-of-pediatric-acute-lymphoblastic-leukemia-a-mixed-methods-study
#17
Sara Folta, Winnie Chang, Rachel Hill, Michael Kelly, Susan Meagher, W Paul Bowman, Fang Fang Zhang
BACKGROUND: Survivors of pediatric acute lymphoblastic leukemia (ALL) may experience unhealthy weight gain during treatment, which has been associated with higher risk for chronic health issues. OBJECTIVE: The purpose of this study was to obtain feedback on weight management in pediatric ALL survivors and on the content and implementation of a Web-based weight management program. METHODS: Study participants included 54 parent survey respondents and 19 pediatric oncology professionals in 4 focus groups...
February 9, 2017: JMIR Cancer
https://www.readbyqxmd.com/read/28387491/-experimental-study-on-the-intolerance-of-uncertainty-and-cognitive-biases-in-parents-of-child-cancer-survivor
#18
M Vander Haegen, A M Etienne, C Piette
Studies in pediatric oncology describe a relative good quality of life in child cancer survivor. However, few studies were interested in the parents of a child cancer survivor. 61 parents are recruited in the Belgian hospitals. Three groups of parents are constituted : the parents whose child is in 4 years of survivorship (group 1), in 5 years of survivorship (group 2) and in 6 years of survivorship (group 3). Clinical scales and a Stroop emotion task are administered. Parents (of the 3 groups) present a low tolerance of uncertainty, have excessive worries about the evolution of the health of their child, and suffer from anxious symptoms...
March 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28383822/preparing-childhood-cancer-survivors-for-transition-to-adult-care-the-young-adult-perspective
#19
Natasha N Frederick, Sharon L Bober, Lexie Berwick, Mary Tower, Lisa B Kenney
BACKGROUND: Childhood cancer survivors (CCSs) remain at risk for developing treatment-associated health conditions as they age; however, many do not obtain recommended follow-up, putting them at unnecessary risk for morbidity. Educational interventions targeted at providing survivors with the knowledge and skills necessary for healthcare independence might improve adherence and outcomes as they transition care to the adult medical system. OBJECTIVE: To identify informational needs, educational preferences, and support that young adult CCSs perceive as beneficial for transition from pediatric to adult medical care...
April 6, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28371178/impact-of-shared-care-program-in-follow-up-of-childhood-cancer-survivors-an-intervention-study
#20
Stéphane Ducassou, Maïté Chipi, Aurélie Pouyade, Mélanie Afonso, Jean-Louis Demeaux, Gérard Ducos, Yves Pérel, Sophie Ansoborlo
BACKGROUND: With the growing rate of childhood cancer cure and the risks of sequelae, long-term follow-up (FU) of survivors is a central issue. Several models have been proven far from satisfactory. Shared care FU is the result of collaboration between general practitioners (GPs) and cancer centers. We sought to demonstrate the feasibility of setting up a shared care program based on the patient-centered education of GPs and to evaluate the impact of this model in an intervention study...
April 1, 2017: Pediatric Blood & Cancer
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