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https://www.readbyqxmd.com/read/28544665/humidified-high-flow-nasal-cannula-oxygen-in-bronchiolitis-reduces-need-for-invasive-ventilation-but-not-intensive-care-admission
#1
Chong Tien Goh, Lynette J Kirby, David N Schell, Jonathan R Egan
AIM: To describe the changes to paediatric intensive care unit (PICU) admission patterns and ventilation requirements for children with bronchiolitis following the introduction of humidified high-flow nasal cannula oxygen outside the PICU. METHODS: Retrospective study comparing patients <24 months of age with a discharge diagnosis of bronchiolitis admitted to the PICU. A comparison was made between those before humidified high-flow nasal cannula oxygen use (year 2008) to those immediately following the introduction of humidified high-flow nasal cannula oxygen use (year 2011) and those following further consolidation of humidified high-flow nasal cannula oxygen use outside the PICU (year 2013)...
May 23, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28544539/intensive-care-unit-admissions-and-ventilation-support-in-infants-with-bronchiolitis
#2
Ed Oakley, Vi Chong, Meredith Borland, Jocelyn Neutze, Natalie Phillips, David Krieser, Stuart Dalziel, Andrew Davidson, Susan Donath, Kim Jachno, Mike South, Amanda Fry, Franz E Babl
OBJECTIVES: To describe the rate of intensive care unit (ICU) admission, type of ventilation support provided and risk factors for ICU admission in infants with bronchiolitis. DESIGN: Retrospective review of hospital records and Australia and New Zealand Paediatric Intensive Care (ANZPIC) registry data for infants 2-12 months old admitted with bronchiolitis. SETTING: Seven Australian and New Zealand hospitals. These infants were prospectively identified through the comparative rehydration in bronchiolitis (CRIB) study between 2009 and 2011...
May 19, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28544511/computational-fluid-dynamics-evaluation-of-posterior-septectomy-as-a-viable-treatment-option-for-large-septal-perforations
#3
Bradley A Otto, Chengyu Li, Alexander A Farag, Benjamin Bush, Jillian P Krebs, Ryan D Hutcheson, Kanghyun Kim, Bhakthi Deshpande, Kai Zhao
BACKGROUND: Numerous surgical techniques exist to treat nasal septal perforation (NSP). The surgical closure of large NSPs (>2 cm) is still challenging. Posterior septectomy has been reported as a simple alternative to treat large NSP, yet its mechanisms for symptom relief are not clear, and if failed, its consequence cannot be easily reversed. METHODS: Ten NSP patients were recruited: 5 underwent posterior septectomy and 5 underwent conventional flap or button repair...
May 23, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28534235/nasal-high-flow-in-management-of-children-with-status-asthmaticus-a-retrospective-observational-study
#4
Florent Baudin, Alexandra Buisson, Blandine Vanel, Bruno Massenavette, Robin Pouyau, Etienne Javouhey
BACKGROUND: Asthma is the most common obstructive airway disease in children and adults. Nasal high flow (NHF) is a recent device that is now used as a primary support for respiratory distress. Several studies have reported use of NHF as a respiratory support in status asthmaticus; however, there are no data to recommend such practice. We therefore conducted this preliminary study to evaluate NHF therapy for children with status asthmaticus admitted to our PICU in order to prepare a multicentre randomized controlled study...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28524026/-high-flow-nasal-cannulae-oxygen-in-patients-with-respiratory-failure-a-meta-analysis
#5
Weigang Yue, Zhigang Zhang, Caiyun Zhang, Liping Yang, Jufang He, Yuying Hou, Ying Tang, Jinhui Tian
OBJECTIVE: To systematically evaluate the efficacy of high-flow nasal cannulae oxygen (HFNC) in patients with respiratory failure. METHODS: Computerized PubMed, Embase, Web of Science, the Cochrane Library, CNKI, CBM, VIP, Wanfang Database up to March 31st, 2017, all published available randomized controlled trials (RCTs) or cohort studies about HFNC therapy for patients with respiratory failure were searched. The control group was treated with face mask oxygen therapy (FM) or non-invasive positive pressure ventilation (NIPPV), while the experimental group was treated with HFNC...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28523583/respiratory-support-after-extubation-noninvasive-ventilation-or-high-flow-nasal-cannula-as-appropriate
#6
Tommaso Mauri, Giacomo Grasselli, Samir Jaber
No abstract text is available yet for this article.
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28506664/heliox-delivered-by-high-flow-nasal-cannula-improves-oxygenation-in-infants-with-respiratory-syncytial-virus-acute-bronchiolitis
#7
Wael Seliem, Amira M Sultan
OBJECTIVE: The objective of this study is to evaluate the hypothesis that use of heliox would result in improvement of gas exchange when used with high flow nasal cannula in infants with RSV acute bronchiolitis. METHODS: All patients that met the inclusion criteria were randomized to either heliox (70:30) or air-oxygen mixture 30% via high flow nasal cannula at 8L/min for a continuous 24h. Measurements were taken at baseline, after 2h, and at the end of the 24h...
May 12, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28505486/respiratory-support-techniques-to-avoid-desaturation-in-critically-ill-patients-requiring-endotracheal-intubation-a-systematic-review-and-meta-analysis
#8
REVIEW
Vincenzo Russotto, Andrea Cortegiani, Santi Maurizio Raineri, Cesare Gregoretti, Antonino Giarratano
PURPOSE: To evaluate which respiratory support method for critically ill patients undergoing endotracheal intubation (ETI) is associated with less desaturation. METHODS: We searched PubMed, Cochrane Library, Scopus and CINAHL databases. We included randomized (RCT) and non-randomized (non-RCT) studies investigating any method of respiratory support before/during ETI compared to a reference control. RESULTS: Apneic oxygenation (ApOx) was the most commonly investigated respiratory support technique for critically ill patients undergoing intubation (4 RCTs, 358 patients)...
May 8, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28504355/home-high-flow-nasal-cannula-as-a-treatment-for-severe-tracheomalacia-a-pediatric-case-report
#9
Kevin Vézina, Sophie Laberge, The Thanh Diem Nguyen
Tracheomalacia refers to a softness of the tracheal cartilage that makes the airway more susceptible to collapse. In contrast to milder cases where conservative therapy is preferred, severe tracheomalacia is often a life threatening condition requiring more aggressive management. For children with this condition, a variety of treatment options are available. To our knowledge, this is the first report of home high-flow nasal cannula as an alternative therapy to continuous positive airway pressure (CPAP) and surgical procedures in a pediatric patient with severe extensive tracheomalacia...
May 15, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28489289/introducing-high-flow-nasal-cannula-to-the-neonatal-transport-environment
#10
Michael A Boyle, Arunava Dhar, Susan Broster
We are encouraged to see that other neonatal transport services are using High-Flow nasal cannula (HFNC) respiratory support during neonatal transport as outlined by Brunton et al (1). The experiences appear to be broadly similar across the two services, however, due to the central location of the neonatal transport base and the well served road network in the East of England region air transports are not conducted. Despite the increasing numbers of articles relating to HFNC use in neonatal units and consensus statements on best practice there is a relative paucity of data relating to its use on transport (2,3)...
May 10, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28487415/randomized-comparison-of-helmet-cpap-versus-high-flow-nasal-cannula-oxygen-in-pediatric-respiratory-distress
#11
Giovanna Vitaliti, Maria Concetta Vitaliti, Maria Carla Finocchiaro, Vita Antonella Di Stefano, Piero Pavone, Nassim Matin, Nazgol Motamed-Gorji, Riccardo Lubrano, Raffaele Falsaperla
BACKGROUND: The current study aimed to compare the efficacy and safety of 2 noninvasive respiratory support methods, which included helmet CPAP and high-flow nasal cannula (HFNC) in children with respiratory distress admitted to a pediatric intermediate care unit. METHODS: This study was a prospective observational study conducted on children with respiratory distress (age 1-24 months) who were admitted to our acute and emergency operative unit. All included subjects were randomly treated with helmet CPAP or HFNC in a 1:1 fashion until their clinical picture, oxygen saturation, and arterial blood gas (ABG) parameters resolved...
May 9, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28474861/group-2-innate-lymphoid-cells-are-elevated-and-activated-in-chronic-rhinosinusitis-with-nasal-polyps
#12
Julie A Poposki, Aiko I Klingler, Bruce K Tan, Pejman Soroosh, Homayon Banie, Gavin Lewis, Kathryn E Hulse, Whitney W Stevens, Anju T Peters, Leslie C Grammer, Robert P Schleimer, Kevin C Welch, Stephanie S Smith, David B Conley, Joseph R Raviv, James G Karras, Omid Akbari, Robert C Kern, Atsushi Kato
BACKGROUND: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. Although T helper cytokines are released from T cells, innate lymphoid cells (ILC) are also known to produce high levels of the same cytokines. However, the presence of various types of ILC in CRS is poorly understood. OBJECTIVE: The objective of this study was to fully characterize the presence of all ILC subsets in CRS and to identify phenotypical differences of group 2 ILC (ILC2) in CRSwNP compared to ILC2 from non-type 2 inflamed areas...
April 19, 2017: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/28470831/physiological-effects-of-titrated-oxygen-via-nasal-high-flow-cannulae-in-copd-exacerbations-a-randomized-controlled-cross-over-trial
#13
Janine Pilcher, Leonie Eastlake, Michael Richards, Sharon Power, Terrianne Cripps, Susan Bibby, Irene Braithwaite, Mark Weatherall, Richard Beasley
BACKGROUND AND OBJECTIVE: Increased arterial carbon dioxide tension (PaCO2 ) is an important complication of acute exacerbations of COPD. The effects of nasal high-flow cannulae (NHF) on PaCO2 in patients with COPD exacerbations, and whether this therapy should be used in this clinical situation, are less certain. We aimed to investigate the effect of NHF on PaCO2 in patients admitted to hospital with a COPD exacerbation. METHODS: We performed a single-centre randomized controlled cross-over trial in 24 hospital inpatients with acute exacerbations of COPD receiving oxygen via standard nasal prongs (SNPs)...
May 4, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28466461/high-flow-nasal-cannula-to-prevent-postextubation-respiratory-failure-in-high-risk-non-hypercapnic-patients-a-randomized-multicenter-trial
#14
Rafael Fernandez, Carles Subira, Fernando Frutos-Vivar, Gemma Rialp, Cesar Laborda, Joan Ramon Masclans, Amanda Lesmes, Luna Panadero, Gonzalo Hernandez
BACKGROUND: Extubation failure is associated with increased morbidity and mortality, but cannot be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation respiratory failure in low-risk patients. OBJECTIVE: To demonstrate that HFNC reduces postextubation respiratory failure in high-risk non-hypercapnic patients compared with conventional oxygen. METHODS: Randomized, controlled multicenter trial in patients who passed a spontaneous breathing trial...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28463044/aerosol-delivery-with-two-nebulizers-through-high-flow-nasal-cannula-a-randomized-cross-over-single-photon-emission-computed-tomography-computed-tomography-study
#15
Jonathan Dugernier, Michel Hesse, Thibaud Jumetz, Emilie Bialais, Jean Roeseler, Virginie Depoortere, Jean-Bernard Michotte, Xavier Wittebole, Stephan Ehrmann, Pierre-François Laterre, François Jamar, Gregory Reychler
BACKGROUND: High-flow nasal cannula use is developing in ICUs. The aim of this study was to compare aerosol efficiency by using two nebulizers through a high-flow nasal cannula: the most commonly used jet nebulizer (JN) and a more efficient vibrating-mesh nebulizer (VN). METHODS: Aerosol delivery of diethylenetriaminepentaacetic acid labeled with technetium-99m (4 mCi/4 mL) to the lungs by using a VN (Aerogen Solo(®); Aerogen Ltd., Galway, Ireland) and a constant-output JN (Opti-Mist Plus Nebulizer(®); ConvaTec, Bridgewater, NJ) through a high-flow nasal cannula (Optiflow(®); Fisher & Paykel, New Zealand) was compared in six healthy subjects...
May 2, 2017: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/28462226/preventive-post-extubation-high-flow-nasal-oxygen-therapy-versus-non-invasive-ventilation-a-substitutive-or-a-complementary-ventilatory-strategy
#16
EDITORIAL
Christophe Girault, Gaëtan Béduneau, Dorothée Carpentier, Benoît Misset
No abstract text is available yet for this article.
March 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28459761/a-novel-weaning-protocol-for-high-flow-nasal-cannula-in-the-picu
#17
Kristina A Betters, Kiran B Hebbar, Courtney McCracken, David Heitz, Stephanie Sparacino, Toni Petrillo
OBJECTIVE: High-flow nasal cannula use in the PICU continues to increase; however, a protocol for weaning patients has yet to be published. This study aimed to create an efficient and safe protocol for weaning high-flow nasal cannula. DESIGN: A Respiratory Assessment Score was created using two validated scoring systems. A protocol was established for set "holidays" off high-flow nasal cannula, where nasal cannula flow was reduced to age-based low-flow nasal cannula rates if Respiratory Assessment Scores met certain criteria...
April 27, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28459412/-high-flow-nasal-cannula-in-patients-after-trachea-extubation
#18
Jiawei Shen, Youzhong An
Acute respiratory failure (ARF) is one primary cause of intensive care unit (ICU) admittance, which is usually treated with intubation and mechanical ventilation in order to maintain a necessary ventilation and oxygenation function. After the remove of trachea tube, available oxygenation supports include nasal cannula, venturi mask, non-invasive ventilator and high flow nasal cannula (HFNC). In this article we reviewed the physiological mechanism related to HFNC therapy and trails about the application of HFNC in extubated patients...
January 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28459344/not-just-oxygen-mechanisms-of-benefit-from-high-flow-nasal-cannula-in-hypoxemic-respiratory-failure
#19
Ewan C Goligher, Arthur S Slutsky
No abstract text is available yet for this article.
May 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28459282/use-of-nasal-high-flow-in-stable-copd-rationale-and-physiology
#20
Lara Pisani, Maria Laura Vega
High-flow nasal cannula (HFNC) is a device able to deliver heated and humidified oxygen at high flows (up to 60 L/minutes). Potential benefits of HFNC are several and include the improvement of lung mucociliary clearance, the washout of upper airway dead space, the generation of a low level of positive airway pressure (PEEP effect), the decrease in inspiratory resistance and at the same time the increase in expiratory resistance. The present review aimed to describe the evidence surrounding the use of HFNC in stable chronic obstructive pulmonary disease patients...
May 1, 2017: COPD
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