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Biovascular scaffold

Sundeep Mishra
In the field of medicine and cardiology newer therapy and devices have been launched with a huge promise and a lot of hype. Unfortunately, over the course of time, a good many of them like biovascular scaffold, renal denervation and intra-aortic balloon pump have failed to live up to their initial promise so much so that some of them have been withdrawn. The reason for this downfall may be multifold from incomplete understanding of the patho-physiology of disease, incomplete understanding of mechanism of action of the therapy, in-appropriate application in clinical practice, in-efficient therapy development related to flawed trial design, regulatory impediments placed on the trials or deficits in application of scientific techniques...
January 2018: Indian Heart Journal
Diego A Arroyo, Sara Schukraft, Zacharenia Kallinikou, Jean-Christophe Stauffer, Gérard Baeriswyl, Jean-Jacques Goy, Mario Togni, Stéphane Cook, Serban Puricel
Aims: To compare endothelium-dependent vasomotor function and vascular healing 15 months after implantation of two new-generation drug-eluting stents and biovascular scaffolds (BVS). Methods and results: A total of 28 patients previously treated with a SYNERGY stent (bioabsorbable polymer everolimus-eluting stents (BP-EES)), a PROMUS stent (persistent polymer everolimus-eluting stents (PP-EES)) or an ABSORB (BVS) underwent control coronary angiography, 15 months after implantation, coupled with optical coherence tomography imaging and supine bicycle exercise...
2018: Open Heart
Bernardo Cortese, Alfonso Ielasi, Elisabetta Moscarella, Bruno Loi, Giuseppe Tarantini, Francesco Pisano, Alessandro Durante, Giampaolo Pasquetto, Alessandro Colombo, Gabriele Tumminello, Luciano Moretti, Paolo Calabrò, Pietro Mazzarotto, Attilio Varricchio, Maurizio Tespili, Roberto A Latini, Gianfranco Defilippi, Donatella Corrado, Giuseppe Steffenino
The Absorb biovascular scaffold (BVS) is a bioresorbable, everolimus-eluting scaffold whose data on real-world patients with complex lesions are limited. Short-term follow-up from recent studies point to a higher rate of 30-day thrombosis than observed with drug-eluting stents. We aimed to understand the short-term safety and efficacy of BVS. Registro Absorb Italiano (RAI, is an Italian, prospective, multicenter registry not funded, whose aim is to investigate BVS performance through a 5-year follow-up of all consecutive patients who have undergone successful implantation of ≥1 BVS in different clinical/lesion subsets...
June 15, 2017: American Journal of Cardiology
Bernardo Cortese, Davide Piraino, Roberto A Latini, Dennis Zavalloni, Alfonso Ielasi, Piefrancesco Agostoni, Pietro Mazzarotto, Maurizio Tespili, Romano Seregni
AIMS: Radial strength of bioresorbable vascular scaffolds (BVS) implanted in coronary arteries is still under debate. Moreover, their final shape patterns, when implanted in an all-comer, unselected population, have not yet been completely correlated with clinical outcome and should be better investigated. METHODS AND RESULTS: A multicenter collaborative analysis was performed on all consecutive patients with native coronary artery disease undergoing PCI with intravascular imaging-guided BVS implantation...
February 1, 2017: International Journal of Cardiology
Dario Buccheri, Davide Piraino, Giuseppe Andolina
No abstract text is available yet for this article.
July 1, 2016: International Journal of Cardiology
Bernardo Cortese, Pedro Silva Orrego, Kazuyuki Yahagi, Renu Virmani
No abstract text is available yet for this article.
July 1, 2016: International Journal of Cardiology
Enrico Cerrato, Francesco Tomassini, Cristina Rolfo, Andrea Gagnor, Ferdinando Varbella
We reported a case of a fit and active 48 years' old woman presented with acute coronary syndrome due to a spontaneous coronary dissection (SCAD) treated with bioresorbable scaffolds (BVS) implantation guided by intravascular ultrasounds (IVUS) with immediate and long-term good results.
April 2017: Cardiovascular Intervention and Therapeutics
Bernardo Cortese, Dario Buccheri, Pedro Silva Orrego, Giuseppe Biondi-Zoccai
We present a case of late acquired bare-metal stent malapposition and uncovered struts, visible at angiography and confirmed by optical frequency domain imaging. In the same patient, an everolimus-eluting biovascular scaffold in another vessel was well apposed and all struts were covered. This case highlights the potential heterogeneity in the evolution of atherosclerotic plaques and response to different devices in the same patient.
August 2015: Journal of Invasive Cardiology
Pratap Chandra Rath, Krupal C Reddy, Manoj K Agarwala, Bharat V Purohit
The everolimus-eluting biovascular scaffold (BVS) does not contain any metal, therefore struts are not evident angiographically. Two adjacent platinum radio-opaque markers at each end facilitate precise location of stent ends. Here we report one case of anomalous left main stenting using BVS. The BVS got accidentally distorted in left main during the procedure, which was not visible on angiography but detected on OCT.
May 2015: Indian Heart Journal
Dario Buccheri, Marco Valgimigli, Bernardo Cortese
No abstract text is available yet for this article.
June 1, 2015: International Journal of Cardiology
Bernardo Cortese, Pedro Silva Orrego, Renu Virmani
Late strut malapposition of currently available stents is a major issue, associated with an increased risk of stent thrombosis. To this day, biovascular scaffolds showed an increased immediate risk of struts malapposition, that however resulted reduced after a few months. Little is known about late acquired struts malapposition of biovascular scaffolds. We here describe two cases that recently occurred in our patients, and we speculate on possible mechanisms for this unexpected and potentially lethal complication...
October 2015: Catheterization and Cardiovascular Interventions
Bernardo Cortese, Pedro Silva Orrego, Rodrigo Sebik, Marco Sesana, Francesco Pisano, Dennis Zavalloni, Giuseppe Steffenino, Romano Seregni
No abstract text is available yet for this article.
December 15, 2014: International Journal of Cardiology
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