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Proliferative vitreoretinopathy

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https://www.readbyqxmd.com/read/28225198/adjunctive-steroid-therapy-versus-antibiotics-alone-for-acute-endophthalmitis-after-intraocular-procedure
#1
REVIEW
Carole H Kim, Monica F Chen, Anne L Coleman
BACKGROUND: Endophthalmitis refers to severe infection within the eye that involves the aqueous humor or vitreous humor, or both, and threatens vision. Most cases of endophthalmitis are exogenous (i.e. due to inoculation of organisms from an outside source), and most exogenous endophthalmitis is acute and occurs after an intraocular procedure. The mainstay of treatment is emergent administration of broad-spectrum intravitreous antibiotics. Due to their anti-inflammatory effects, steroids in conjunction with antibiotics have been proposed to be beneficial in endophthalmitis management...
February 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28196061/therapeutic-outcomes-after-endoresection-of-complex-retinal-capillary-hemangioblastoma
#2
Murat Karacorlu, Mumin Hocaoglu, Isil Sayman Muslubas, Mehmet Giray Ersoz, Serra Arf
PURPOSE: To evaluate the anatomical and functional outcomes after endoresection of complex retinal capillary hemangioblastoma (RCH). METHODS: Retrospective case series of 12 patients (13 eyes), all treated with pars plana vitrectomy, endodiathermy of feeding and draining vessels, endoresection of RCH and silicone oil injection. RESULTS: The mean age at the time of surgery was 32.5 ± 15.9 years. The mean follow-up duration after initial surgery was 50...
February 10, 2017: Retina
https://www.readbyqxmd.com/read/28195617/pediatric-traumatic-retinal-detachments-clinical-characteristics-and-outcomes
#3
Sabahattin Sul, Gökhan Gurelik, Safak Korkmaz, Sengül Ozdek, Berati Hasanreisoglu
BACKGROUND AND OBJECTIVE: To compare clinical characteristics and surgical outcomes of retinal detachment (RD) after open globe injuries (OGIs) and closed globe injuries (CGIs). PATIENTS AND METHODS: One hundred ten eyes of 110 patients aged 17 years or younger who underwent primary RD repair after OGI and CGI between 2010 and 2013 were reviewed retrospectively. RESULTS: Cataract (59.8% vs. 21.7%; P = .002) and vitreous hemorrhage (54% vs...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28163930/surgical-management-of-traumatic-retinal-detachment-with-primary-vitrectomy-in-adult-patients
#4
Katarzyna Nowomiejska, Tomasz Choragiewicz, Dorota Borowicz, Agnieszka Brzozowska, Joanna Moneta-Wielgos, Ryszard Maciejewski, Anselm G Jünemann, Robert Rejdak
Purpose. To evaluate functional and anatomical results of pars plana vitrectomy (PPV) in the retinal detachment (RD) followed by severe eye trauma. Methods. Retrospective analysis of medical records of forty-one consecutive patients treated with 23-gauge PPV due to traumatic RD. Age, gender, timing of PPV, visual acuity, and presence of intraocular foreign body (IOFB) and proliferative vitreoretinopathy (PVR) were included in the analysis. Results. Mean age of patients was 47 years; the majority of patients were men (88%)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28160248/gas-tamponade-for-retinectomy-in-pvr-related-retinal-detachments-a-retrospective-study
#5
Vasileios T Papastavrou, Irini Chatziralli, Dominic McHugh
INTRODUCTION: The purpose of the study was to evaluate the anatomical and functional results in patients with proliferative vitreoretinopathy (PVR) treated with retinectomy and perfluoro-octane gas (C3F8) as a tamponade agent. METHODS: 12 patients with inferior and anterior complicated PVR-related retinal detachment, who were treated with retinectomy, where C3F8 was used as the tamponade agent were examined. Primary outcome was the anatomical success, while visual acuity, existence of an epiretinal membrane (ERM) and intraocular pressure (IOP) postoperatively were secondary outcomes...
February 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28157410/short-term-vitreoretinal-tamponade-with-heavy-liquid-following-surgery-for-giant-retinal-tear
#6
Maya Eiger-Moscovich, Assaf Gershoni, Ruth Axer-Siegel, Dov Weinberger, Rita Ehrlich
PURPOSE: To study the efficacy and outcomes of short-term postoperative vitreoretinal tamponade with perfluorocarbon heavy liquid in patients with giant retinal tear. MATERIALS AND METHODS: The study group consisted of 13 consecutive patients (13 eyes) who presented with giant retinal tear at a tertiary medical center in 2011-2015 and were treated with vitrectomy followed by short-term tamponade with perfluorocarbon heavy liquid. A minimum of 3 months' follow-up was required for inclusion...
February 3, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28147403/intraocular-dexamethasone-implant-as-adjunct-to-silicone-oil-tamponade-for-proliferative-vitreoretinopathy
#7
M Sherif, T J Wolfensberger
Background Proliferative vitreoretinopathy (PVR) occurs in 10 % of patients with retinal detachment and is characterized by excessive epi-, sub- or intraretinal contraction. Corticosteroids have been shown to counter this contraction. Patients and Methods Retrospective review of 5 patients (3 females, 2 males) with recurrent retinal detachment with stage C PVR. The mean age was 61.2 ± 20.5 years and myopia > - 5.0 dioptres was present in 3 eyes. Patients were treated with 23 g vitrectomy, retinectomy and endolaser, dexamethasone (Ozurdex®) injection under perfluorocarbone and 5500 cs silicone oil tamponade...
February 1, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28138811/pars-plana-vitrectomy-with-360%C3%A2-versus-localized-laser-retinopexy-in-the-management-of-retinal-detachment-with-undetected-breaks-intraoperatively-a-retrospective-comparative-interventional-study
#8
Chuandi Zhou, Zhi Zheng, Qinghua Qiu
The purpose of this study is to compare the efficacy of intraoperative 360° and localized laser retinopexy in 23-gauge pars plana vitrectomy (PPV) for rhegmatogenous retinal detachments (RRD) with undetected retinal breaks intraoperatively. This is a retrospective, comparative, interventional study. Medical records of 48 consecutive eyes with RRD of intraoperative undetected retinal breaks were reviewed. Nineteen patients (group I) received 360° laser retinopexy in PPV, while the remaining 29 patients (group II) underwent localized laser retinopexy...
January 30, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28138219/resveratrol-inhibits-transforming-growth-factor-%C3%AE-2-induced-epithelial-to-mesenchymal-transition-in-human-retinal-pigment-epithelial-cells-by-suppressing-the-smad-pathway
#9
Ching-Long Chen, Yi-Hao Chen, Ming-Cheng Tai, Chang-Min Liang, Da-Wen Lu, Jiann-Torng Chen
Proliferative vitreoretinopathy (PVR) is the main cause of failure following retinal detachment surgery. Transforming growth factor (TGF)-β2-induced epithelial-to-mesenchymal transition (EMT) plays an important role in the development of PVR, and EMT inhibition decreases collagen gel contraction and fibrotic membrane formation, resulting in prevention of PVR. Resveratrol is naturally found in red wine and has inhibitory effects on EMT. Resveratrol is widely used in cardioprotection, neuroprotection, chemotherapy, and antiaging therapy...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28128794/patching-retinal-breaks-with-seprafilm-for-treating-retinal-detachments-in-humans-9-years-of-follow-up
#10
M Haruta, M Arai, J Sueda, T Hirose, R Yamakawa
PurposeTo describe the long-term surgical outcomes of four patients treated for retinal detachment using Seprafilm as a novel technique.MethodsRetinal breaks in four eyes were covered with Seprafilm using a transvitreal approach after cataract surgery, pars plana vitrectomy, fluid-air exchange, and laser photocoagulation. Neither long-standing gas nor silicone oil was used. The patients were not instructed to maintain a specific head positioning postoperatively.ResultsSuccessful retinal reattachment was achieved with a single surgery in all four eyes, and none developed proliferative vitreoretinopathy...
January 27, 2017: Eye
https://www.readbyqxmd.com/read/28125442/a-surgical-technique-for-the-management-of-retinal-detachment-associates-with-severe-proliferative-vitreoretinopathy
#11
Homayoun Tabandeh
No abstract text is available yet for this article.
January 25, 2017: Retina
https://www.readbyqxmd.com/read/28114583/role-of-caveolin-1-for-blocking-the-epithelial-mesenchymal-transition-in-proliferative-vitreoretinopathy
#12
Yosuke Nagasaka, Hiroki Kaneko, Fuxiang Ye, Shu Kachi, Tetsu Asami, Seiichi Kato, Kei Takayama, Shiang-Jyi Hwang, Keiko Kataoka, Hideyuki Shimizu, Takeshi Iwase, Yasuhito Funahashi, Akiko Higuchi, Takeshi Senga, Hiroko Terasaki
Purpose: Proliferative vitreoretinopathy (PVR) is one of the most severe ocular diseases. Fibrotic changes in retinal cells are considered to be involved in the pathogenesis of PVR. Epithelial-mesenchymal transition (EMT) of RPE cells is one of the main concepts in the pathogenesis of fibrovascular membranes (FVMs) in PVR. In this study, we examined the expression of Caveolin-1 in human FVMs from patients with PVR. We also examined the role of Caveolin-1 in the pathogenesis of PVR. Methods: Western blotting, real-time PCR, and immunohistochemistry were performed with human FVMs and mouse eyes with PVR...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28106707/association-study-between-polymorphisms-of-the-p53-and-lymphotoxin-alpha-lta-genes-and-the-risk-of-proliferative-vitreoretinopathy-retinal-detachment-in-a-mexican-population
#13
Natalia Quiroz-Casian, David Lozano-Giral, Antonio Miranda-Duarte, Ivan Garcia-Montalvo, Jose L Rodriguez-Loaiza, Juan C Zenteno
PURPOSE: To report the results of an association study between single-nucleotide polymorphisms of the p53 and LTA genes and the risk of proliferative vitreoretinopathy (PVR)/retinal detachment (RD) in a Mexican cohort. METHODS: A total of 380 unrelated subjects were studied, including 98 patients with primary rhegmatogenous RD without PVR, 82 patients with PVR after RD surgery, and 200 healthy, ethnically matched subjects. Genotyping of single-nucleotide polymorphisms rs1042522 (p53 gene) and rs2229094 (LTA gene) was performed by direct nucleotide sequencing...
January 18, 2017: Retina
https://www.readbyqxmd.com/read/28101042/use-of-internal-limiting-membrane-autograft-in-primary-vitrectomy-for-rhegmatogenous-retinal-detachment
#14
Sergio Eustolio Hernández-Da Mota, Jorge Francisco Béjar-Cornejo
During a pars plana vitrectomy, an unplanned retinotomy in the raphe was performed in a 55-year-old female patient with rhegmatogenous retinal detachment and proliferative vitreoretinopathy. Since diathermy and laser therapy were not available at that moment, it was decided to peel off a small graft of the internal limiting membrane adjacent to the retinotomy site which had been previously stained with Brilliant Blue G. The graft was displaced under perfluorocarbon fluids and placed inside the retinotomy. Three weeks after surgery, the apparent closure of the retinotomy was observed clinically...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28088932/trauma-of-the-globe-state-of-art-in-global-and-in-china
#15
Zhuo Chen, Shi-Ming Li
Current states of traumatic eye injury are reviewed in terms of epidemiology in the developing countries and developed countries, causes of the trauma, eye injury types, traumatic eye injury diagnostic methods and treatments. Trauma-caused vision-threatening conditions such as open global injury, traumatic optic neuropathy and proliferative vitreoretinopathy are particularly discussed. Also the most updated clinic research in China as Eye Injury Vitrectomy Study is discussed. At the end, the current achievements and research in traumatic eye injury in the world are summerized...
December 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28077370/preoperative-aqueous-humour-flare-values-do-not-predict-proliferative-vitreoretinopathy-in-patients-with-rhegmatogenous-retinal-detachment
#16
Verena C Mulder, Jan Tode, Elon Hc van Dijk, Konstantine Purtskhvanidze, Johann Roider, Jan C van Meurs, Felix Treumer
BACKGROUND/AIMS: Patients with rhegmatogenous retinal detachment (RRD) who develop postoperative proliferative vitreoretinopathy (PVR) have been found to have higher preoperative laser flare values than patients with RRD who do not develop this complication. Measurement of laser flare has therefore been proposed as an objective, rapid and non-invasive method for identifying high-risk patients. The purpose of our study was to validate the use of preoperative flare values as a predictor of PVR risk in two additional patient cohorts, and to confirm the sensitivity and specificity of this method for identifying high-risk patients...
January 11, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28057646/incidence-mechanism-and-outcomes-of-schisis-retinal-detachments-revealed-through-a-prospective-population-based-study
#17
Kanmin Xue, Mahiul M K Muqit, Eric Ezra, Stephen J Charles, David Yorston, Arijit Mitra, Chetan K Patel
AIM: To determine the incidence, presentation and outcomes of progressive sight-threatening retinal detachment (RD) complicating degenerative retinoschisis. METHODS: We conducted the first prospective population-based epidemiological study of progressive schisis detachment over a 1-year period (2014-2015) in the UK. Case ascertainment was via monthly British Ophthalmological Surveillance Unit reporting cards sent to all ophthalmologists in the UK. For each reported case, data were collected using incident and 6 months follow-up questionnaires gathering information including demographic, presenting symptoms, retinal findings, primary management, primary outcome, secondary management and secondary outcome...
January 5, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28053500/comparison-of-outcomes-scleral-buckling-and-pars-plana-vitrectomy-versus-vitrectomy-alone-for-primary-repair-of-rhegmatogenous-retinal-detachment
#18
Luke B Lindsell, Robert A Sisk, Daniel M Miller, Robert E Foster, Michael R Petersen, Christopher D Riemann, Robert K Hutchins
OBJECTIVE: To assess the combination of scleral buckling (SB) and pars plana vitrectomy (PPV) versus PPV alone in the primary repair of rhegmatogenous retinal detachments (RRDs). METHODS: The current study was a retrospective, comparative, interventional, consecutive case series of 179 eyes of 174 patients who underwent primary RRD repair by five surgeons between January 1, 2008 and December 31, 2010, utilizing SB with PPV or PPV. Univariate and multivariate analyses were used to compare the efficacy of the two surgical strategies and assess for risk factors of proliferative vitreoretinopathy (PVR)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28045788/staining-assisted-removal-of-silicone-oil-for-the-identification-of-subclinical-proliferative-vitreoretinopathy
#19
Stanislao Rizzo, Francesco Barca, Francesco Faraldi, Tomasso Caporossi, Gianni Virgili
PURPOSE: Retinal detachment is a frequent complication after removal of silicone oil (ROSO). A retrospective study was conducted to determine whether staining-assisted removal of silicone oil (st-ROSO) allowed better identification and removal of proliferative vitreoretinopathy (PVR) processes compared with a conventional removal of silicone oil technique. METHODS: All individuals underwent pars plana vitrectomy (PPV) and silicone oil fill-in for complicated retinal detachments...
December 30, 2016: Retina
https://www.readbyqxmd.com/read/28033232/choroidal-thickness-changes-after-vitrectomy-with-silicone-oil-tamponade-for-proliferative-vitreoretinopathy-retinal-detachment
#20
Dominik Odrobina, Joanna Gołębiewska, Iwona Maroszyńska
PURPOSE: To access the potential effect of vitrectomy and silicone oil tamponade on the choroid. METHODS: Eighteen patients (18 eyes) who had undergone pars plana vitrectomy with 1,000-cSt silicone oil tamponade for proliferative vitreoretinopathy retinal detachment were included in this retrospective study. All patients underwent ophthalmologic examinations before treatment and 1 week and 1, 3, and 6 months after vitrectomy with silicone oil tamponade. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography (Spectralis; Heidelberg Engineering) in a horizontal and vertical section beneath the fovea...
December 28, 2016: Retina
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