keyword
MENU ▼
Read by QxMD icon Read
search

Cloaca

keyword
https://www.readbyqxmd.com/read/28069328/antimicrobial-activity-of-ceftazidime-avibactam-and-comparator-agents-when-tested-against-bacterial-isolates-causing-infection-in-cancer-patients-2013-2014
#1
Helio S Sader, Mariana Castanheira, Ronald N Jones, Robert K Flamm
We evaluated the antimicrobial susceptibility of 623 Gram-negative organisms causing infection in patients with cancer in 52 United States hospitals (2013-2014) as part of the International Network for Optimal Resistance Monitoring (INFORM) program. Isolates were tested for susceptibility by broth microdilution method. β-lactamase encoding genes were evaluated for all Escherichia coli and Klebsiella spp. with an extended-spectrum β-lactamase (ESBL) phenotype by microarray-based assay. ESBL-phenotype was observed among 17...
November 29, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28058485/the-current-profile-of-persistent-cloaca-and-cloacal-exstrophy-in-japan-the-results-of-a-nationwide-survey-in-2014-and-a-review-of-the-literature
#2
Masayuki Kubota
PURPOSE: The current profile of persistent cloaca (PC) and cloacal exstrophy (CE) in Japan was first examined in 2014. MATERIALS AND METHODS: Information was obtained by sending a questionnaire to 244 university hospitals and children's hospitals. RESULTS: Responses from 113 institutions reported 466 PC cases and 229 CE cases. The incidences of PC and CE from 1980 to 2012 were 0.97 and 0.49 per 100,000 live births, respectively. In the previous 5 years, antenatal abnormalities were found in 57...
January 5, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28039276/the-pharmacodynamics-of-avibactam-in-combination-with-ceftaroline-or-ceftazidime-against-%C3%AE-lactamase-producing-enterobacteriaceae-studied-in-an-in-vitro-model-of-infection
#3
Alasdair MacGowan, Sharon Tomaselli, Alan Noel, Karen Bowker
OBJECTIVES: Pharmacodynamics of β-lactamase inhibitors are an area of intense interest as new β-lactam/β-lactamase inhibitor combinations enter clinical development and clinical practice. Avibactam, a non-β-lactam β-lactamase inhibitor, has been combined with ceftaroline or ceftazidime but these two combinations have not been directly compared. METHODS: Using an in vitro pharmacokinetic model we simulated human drug concentration-time courses associated with ceftaroline 600 mg every 8 h and ceftazidime 2000 mg every 8 h...
December 30, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28032700/management-of-acute-hematogenous-infection-following-total-knee-arthroplasty-a-case-series-of-11-patients
#4
Rui He, Liu Yang, Lin Guo, Hao Chen, Ying Zhang, Dian-Ming Jiang
OBJECTIVE: Acute hematogenous infection is a devastating complication that can occur after total knee arthroplasty (TKA). The best strategies for management of this infection remain controversial. Two-stage revision has been well described as the gold standard for the management of chronic late infections. However, there is a paucity of information presently available on the management and outcomes of patients treated for acute hematogenous infections. The purpose of the present study was to report the outcome of acute hematogenous infections following TKA with the treatment of irrigation, debridement, and retention of the prosthetic components...
November 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28027944/antibiofilm-efficacy-of-green-synthesized-graphene-oxide-silver-nanocomposite-using-lagerstroemia-speciosa-floral-extract-a-comparative-study-on-inhibition-of-gram-positive-and-gram-negative-biofilms
#5
Shatavari Kulshrestha, Shariq Qayyum, Asad U Khan
Biofilm architecture provides bacteria with enhanced antibiotic resistance, thus raising the need to search for alternative therapies that can inhibit the bacterial colonization. In the present study, we synthesized graphene oxide-silver nanocomposite (GO-Ag) by non-toxic and eco-friendly route using a floral extract of Legistromia speciosa (L.) Pers. The gas chromatography-mass spectrometry (GC-MS) analysis of plant extract revealed the presence of compounds which can simultaneously act as reducing and capping agents...
December 24, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28018328/a-mechanism-of-synergistic-effect-of-streptomycin-and-cefotaxime-on-ctx-m-15-type-%C3%AE-lactamase-producing-strain-of-e-cloacae-a-first-report
#6
Lubna Maryam, Asad U Khan
A blaCTX-M-15 gene is one of the most prevalent resistant marker found in member of enterobacteriaceae. It encodes cefotaxime hydrolysing β-lactamase-15 (CTX-M-15) causing resistance against beta lactam antibiotics. Since single antibiotic therapy fails to control infection caused by multidrug resistance strain, therefore combination therapy was came into practice as an effective treatment. We have first time explained the mechanism where two antibiotics of different classes work against resistant strains...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28010058/-epidemiology-and-risk-factors-of-patients-with-intra-abdominal-postsurgical-infection-treated-with-tigecycline-a-cohort-study
#7
G Torres, M Paredes, A Hernández, C García, F Sánchez Bueno, M Canteras, P Parrilla, J Gómez
OBJECTIVE: To study a cohort of patients with intra-abdominal postsurgical infection treated with tigecycline to analyze its effectiveness and mortality related factors. METHODS: Prospective study of patients with intra-abdominal postsurgical infection with microbiological isolation and treated with tigecycline. RESULTS: Out of 103 patients only 61 full fit inclusion criteria. Mean age was 67 year-old and 72% were male. Charlson score was ≥ 3 in 65...
December 23, 2016: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28009141/operative-cystoscopy-in-the-neonatal-period
#8
Salvatore Arena, Tiziana Russo, Patrizia Perrone, Carmelo Romeo
Aim of the study is to report the experience in the last three years about endourological treatment of newborns affected by genito- and urinary malformation, implying critical urinary tract dilatation and bladder mass requiring a neonatal operative management. Seven - four males and three female - patients were treated cystoscopically during the neonatal period. Three newborns with a posterior urethral valves (PUV), underwent a successful ablation of PUV. In a male with infected persistent large mullerian duct and subsequent acute urinary retention, a cystoscopically-assisted catheterization was performed...
December 20, 2016: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/28002109/neonatal-bacterial-conjunctivitis-in-korea-in-the-21st-century
#9
Kang Yeun Pak, Sung Il Kim, Jong Soo Lee
PURPOSE: To investigate the microbial cause and antibiotic susceptibility of neonatal bacterial conjunctivitis in Korean patients in the 21st century. METHODS: We retrospectively reviewed the medical records of patients diagnosed with neonatal bacterial conjunctivitis between January 2000 and December 2015. We recorded the organism, antibiotic susceptibility, and antibiotics used. RESULTS: A total of 82 neonates were included in the study (53 males and 29 females), with a mean age of 17...
December 20, 2016: Cornea
https://www.readbyqxmd.com/read/28000197/-efficacy-evaluation-of-laparoscopic-surgery-for-children-with-persistent-cloaca
#10
Chen Wang, Shuli Liu, Zhen Chen, Long Li, Wei Zheng
OBJECTIVE: To explore the feasibility and efficacy of laparoscopic surgery in the treatment of children with persistent cloaca. METHODS: Clinical data of 26 female children with high type persistent cloaca undergoing operation in the Capital Pediatric Institution between November 2005 and February 2015 were retrospectively analyzed. Mean age of these children was (1.4±1.6) years old. Distal end of rectum locating in the superior border of pubis was the standard of diagnosis...
December 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27994915/intravenous-colistin-use-for-multidrug-resistant-gram-negative-infections-in-pediatric-patients
#11
Ayşe Karaaslan, Eren Çağan, Eda Kepenekli Kadayifci, Serkan Atıcı, Gülşen Akkoç, Nurhayat Yakut, Sevliya Öcal Demir, Ahmet Soysal, Mustafa Bakır
BACKGROUND: The emergence of infections due to multidrug-resistant Gram-negative bacilli (MDR-GNB) has led to the resurrection of colistin use. The data on colistin use and drug-related adverse effects in children are scarce. AIMS: In this study, we aimed to evaluate the clinical efficacy and safety of colistin use in critically ill pediatric patients. STUDY DESIGN: This study has a retrospective study design. METHODS: Sixty-one critically ill children were identified through the department's patient files archive during the period from January 2011 to November 2014...
November 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27993423/corrigendum-to-carbapenem-susceptibility-among-escherichia-coli-klebsiella-pneumoniae-and-enterobacter-cloacae-isolates-obtained-from-patients-in-intensive-care-units-in-taiwan-in-2005-2007-and-2009-diagn-microbiol-infect-dis-2015-81-4-290-295
#12
Shio-Shin Jean, Wen-Sen Lee, Kuan-Jen Bai, Kwok-Woon Yu, Chin-Wang Hsu, Chun-Hsing Liao, Feng-Yi Chang, Wen-Chien Ko, Jiunn-Jong Wu, Yen-Hsu Chen, Yao-Shen Chen, Jien-Wei Liu, Min-Chi Lu, Cheng-Yi Liu, Ray-Jade Chen, Po-Ren Hsueh
No abstract text is available yet for this article.
December 16, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27989362/complications-in-colorectal-surgery
#13
Jason S Frischer, Beth Rymeski
Colorectal pediatric surgery is a diverse field that encompasses many different procedures. The pullthrough for Hirschsprung disease, the posterior sagittal anorectoplasty for anorectal malformations including complex cloaca reconstructions and the ileal pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis present some of the most technically challenging procedures pediatric surgeons undertake. Many children prevail successfully following these surgical interventions, however, a small number of patients suffer from complications following these procedures...
December 2016: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/27988548/a-new-species-of-the-genus-i-paramesotriton-i-caudata-salamandridae-from-fujian-southeastern-china
#14
Zhiyong Yuan, Yunke Wu, Jiajun Zhou, Jing Che
New amphibian species have been constantly discovered throughout southern China, including from areas close to heavily populated cities that remain poorly surveyed for amphibian diversity. We describe a new species of the newt genus Paramesotriton from Fujian, a developed province on the southeastern coast of mainland China. The mitochondrial genealogy suggests that the new species is the sister taxon to Paramesotriton hongkongensis, separated by an uncorrected pairwise distances of 5.8% at the ND2 gene fragment analyzed...
December 12, 2016: Zootaxa
https://www.readbyqxmd.com/read/27986632/structural-insight-into-mode-of-binding-of-meropenem-to-ctx-m-15-type-%C3%AE-lactamase
#15
Lubna Maryam, Asad U Khan
Among Enterobacteriaceae, CTX-M type extended spectrum beta lactamase confers potent hydrolytic activity against cephalosporin group of antibiotics. Strains producing CTX-M type beta lactamase enzymes, show high level of resistance against cefotaxime. Therefore carbapenem antibiotics are used against beta lactamase producing strains. Hence, this study was designed to understand an insight of molecular basis of CTX-M-15 interaction with meropenem, and its effect on CTX-M-15 efficiency. Clinical strain of Enterobacter cloacae (EC-15) was used to clone blaCTX-M-15 gene in E...
December 14, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27986535/reduction-of-quinones-and-nitroaromatic-compounds-by-escherichia-coli-nitroreductase-a-nfsa-characterization-of-kinetics-and-substrate-specificity
#16
Benjaminas Valiauga, Elsie M Williams, David F Ackerley, Narimantas Čėnas
NfsA, a major FMN-associated nitroreductase of E. coli, reduces nitroaromatic compounds via consecutive two-electron transfers. NfsA has potential applications in the biodegradation of nitroaromatic environment pollutants, e.g. explosives, and is also of interest for the anticancer strategy gene-directed enzyme prodrug therapy. However, the catalytic mechanism of NfsA is poorly characterized. Here we examined the NADPH-dependent reduction of quinones (n = 16) and nitroaromatic compounds (n = 12) by NfsA...
December 13, 2016: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/27981921/emerging-trends-of-bloodstream-infections-a-six-year-study-at-a-paediatric-tertiary-care-hospital-in-kabul
#17
Tariq Mahmud Tariq, Esmatullah Rasool
OBJECTIVE: To determine the frequency of pathogens causing bloodstream infections and evaluate their trends and antibiogram patterns among in-patients in a paediatric tertiary care centre. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan in two phases, from January 2010 to December 2015. METHODOLOGY: Results of blood cultures from suspected cases of sepsis admitted in the FMIC, from January 2010 to December 2012 (Period-1), and from January 2013 to December 2015 (Period-2) were completed...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27965626/high-prevalence-of-gut-microbiota-colonization-with-broad-spectrum-cephalosporin-resistant-enterobacteriaceae-in-a-tunisian-intensive-care-unit
#18
Elaa Maamar, Sana Ferjani, Ali Jendoubi, Samia Hammami, Zaineb Hamzaoui, Laure Mayonnove-Coulange, Mabrouka Saidani, Aouatef Kammoun, Amel Rehaiem, Salma Ghedira, Mohamed Houissa, Ilhem Boutiba-Ben Boubaker, Amine Slim, Veronique Dubois
Healthcare-associated infections due to cefotaxime-resistant (CTX-R) Enterobacteriaceae have become a major public health threat, especially in intensive care units (ICUs). Often acquired nosocomially, CTX-R Enterobacteriaceae can be introduced initially by patients at admission. This study aimed to determine the prevalence and genetic characteristics of CTX-R Enterobacteriaceae-intestinal carriage in ICU patients, to evaluate the rate of acquisition of these organisms during hospitalization, and to explore some of the associated risk factors for both carriage and acquisition...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27965456/comprehensive-genome-analysis-of-carbapenemase-producing-enterobacter-spp-new-insights-into-phylogeny-population-structure-and-resistance-mechanisms
#19
Kalyan D Chavda, Liang Chen, Derrick E Fouts, Granger Sutton, Lauren Brinkac, Stephen G Jenkins, Robert A Bonomo, Mark D Adams, Barry N Kreiswirth
: Knowledge regarding the genomic structure of Enterobacter spp., the second most prevalent carbapenemase-producing Enterobacteriaceae, remains limited. Here we sequenced 97 clinical Enterobacter species isolates that were both carbapenem susceptible and resistant from various geographic regions to decipher the molecular origins of carbapenem resistance and to understand the changing phylogeny of these emerging and drug-resistant pathogens. Of the carbapenem-resistant isolates, 30 possessed blaKPC-2, 40 had blaKPC-3, 2 had blaKPC-4, and 2 had blaNDM-1 Twenty-three isolates were carbapenem susceptible...
December 13, 2016: MBio
https://www.readbyqxmd.com/read/27964935/molecular-and-in-silico-analysis-of-a-new-plasmid-mediated-ampc-%C3%AE-lactamase-cmh-2-in-clinical-isolates-of-klebsiella-pneumoniae
#20
Birson Ingti, Monjur Ahmed Laskar, Sudip Choudhury, Anand Prakash Maurya, Deepjyoti Paul, Anupam Das Talukdar, Manabendra Dutta Choudhury, Debadatta Dhar, Atanu Chakravarty, Amitabha Bhattacharjee
Two Klebsiella strains isolated from urine samples were positive for blaAmpC by PCR and showed sequence similarity with CMH-1 (98.6%) after sequencing. It also shares 82% similarity with ACT-1, 85% with MIR-1 and 81% with the chromosomal AmpC gene of Enterobacter cloacae. This gene was associated with the plasmid of IncK type. It has an open reading frame of 381 amino acid with four amino acid substitutions at position D144A, C189R, Q192E, and A195T as compared to CMH-1. When expressed in E.coli DH5α and E...
December 10, 2016: Infection, Genetics and Evolution
keyword
keyword
24027
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"